KINDAI UNIVERSITY


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Kenichi Oshio

Profile

FacultyDepartment of Medicine
PositionLecturer
Degree
Commentator Guidehttps://www.kindai.ac.jp/meikan/686-oshio-kenichi.html
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Mail
Last Updated :2019/07/19

Education and Career

Education

  •  - 1996 , Hiroshima University, Graduate School, Division of Natural Science
  •  - 1991 , Hiroshima University, Faculty of Science

Academic & Professional Experience

  •   2012 ,  - 現在, Lecturer, Kinki University, Faculty of Medicine
  •   1999 ,  - 2007 , Kinki University School of Medicine, Research Associate
  •   2007 , - Kinki University School of Medicine, Assistant Professor
  •   1997 ,  - 1999 , Keio University, Research Assistant
  •   1996 ,  - 1997 , Research Center for Nanodevices
  • Post Doctral Researcher
  • and Systems Hiroshima University,

Research Activities

Research Areas

  • Neuroscience, Neuroscience in general
  • Neuroscience, Neurophysiology and muscle physiology
  • Physics, Mathematical physics/Fundamental condensed matter physics

Research Interests

  • Neuro Science in General, Non-linear Dynamics

Published Papers

  • Neuronal representation of duration discrimination in the monkey striatum., Atsushi Chiba, Ken-ichi Oshio, Masahiko Inase, Physiological Reports, 3(2), e12283, Feb. 2015 , Refereed
  • Possible Functions of Prefrontal Cortical Neurons in Duration Discrimination, Ken-ichi Oshio, Front Integr Neurosci, 5, 25, Jun. 2011 , Refereed
  • Temporal filtering by prefrontal neurons in duration discrimination, Ken-ichi Oshio, Atsushi Chiba, Masahiko Inase, European Journal of Neuroscience, 28, 2333 - 2343, 2008 , Refereed
  • Striatal neurons encoded temporal information in duration discrimination task, Atsushi Chiba, Ken-ichi Oshio, Masahiko Inase, Exp Brain Res, 186, 671 - 676, 2008 , Refereed
  • Delay period activity of monkey prefrontal neurones during duration-discrimination task, Ken-ichi Oshio, Atsushi Chiba, Masahiko Inase, European Journal of Neuroscience, 23, 2779 - 2790, 2006 , Refereed
  • Neuron classification based on temporal firing patterns by the dynamical analysis with changing time resolution (DCT) method, 88(6), 438 - 449, 2003 , Refereed
  • Magnetically evoked EMGs in rats, Chiba A, Oshio K, Inase M, Neurological Research, 25, 87 - 91, 2003 , Refereed
  • Current Oscillations Induced by Recombination Instability in Semiconductors, Ken-ichi Oshio, Hideo Yahata, 65(5), 1490 - 1499, 1996 , Refereed
  • Non-Periodic Current Oscillations in the Gunn-Effect Device with the Impact-Ionization Effect, Ken-ichi Oshio, Hideo Yahata, 64(5), 1823 - 1836, 1995 , Refereed
  • Chaotic Current Oscillations in the Gunn-Effect Device Under the dc and the rf Bias Voltages, Ken-ichi Oshio, Hideo Yahata, 62(10), 3639 - 3650, 1993 , Refereed
  • A trial of the objective structured skill examination in PBL tutorial course, Journal of Medical Education, 7(4), 73 - 75, Aug. 2004
  • Prophylactic effect of repetitive magnetic stimulation against stroke in malignant stroke-prone spontaneously hypertensive rats, The Journal of Japan Biomagnetism and Bioelectromagnetics Society, 19(1), 258 - 259, Jun. 2006
  • Effects of isotonic contraction excised vas deferens of guinea-pigs under pain-related drugs, Biomagnetism interdisciplinary reserch and exploration, 275 - 277, Aug. 2008
  • Neuronal activity in the monkey striatum during a duration discrimination task, Atsushi Chiba, Ken-ichi Oshio, Masahiko Inase, Neuroscience 2005, 35th Annual Meeting of Society for Neuroscience, Washington DC, USA, Program No. 413.5, 2005
  • Analysis of neuronal network of C. elegans by using database of synaptic connectivity for computation, Kawamura K, Oshio K, Iwasaki Y, Morita S, Osana Y, Gomi S, Akiyama E, Omata K, Matsuura T, Oka K, SfN Neuroscience 2004, Program No. 658.3, 2004 , Refereed
  • Neural mechanism for time perception in dorsolateral prefrontal cortex using duration-discrimination task, 4th Forum of European Neuroscience, 2004
  • Neuron classification based on temporal firing patterns by the dynamical analysis with changing time resolution (DCT) method, Ken-ichi Oshio, Michio Nakashima, Satoshi Yamada, Biological Cybernetics, 88(6), 438 - 449, 2003 , Refereed
  • Motor evoked potentials in rats with congential hydrocephalus, Chiba A, Ohta Y, Oshio K, Inase M, Neurological Research, 25, 305 - 308, 2003 , Refereed
  • A trial of the objective structured skill examination in PBL tutorial course, Matsuo O, Inase M, Murata A, Chiba A, Oshio K, Okada K, Ueshima S, Journal of Medical Education, 7(4), 73 - 75, 2003 , Refereed
  • Neuronal Circuit and Native Responses of C. elegans "jointly worked", 14th biennial International C. elegans, June 29 - July 3, 2003, California, USA, 2003
  • Neuronal activity in monkey dorsolateral prefrontal cortex during duration-discrimination task, Sixth IBRO World Congress of Neuroscience, July 10-15, 2003, Prague, Czech Republic., 2003
  • Geometrical structure of the neuronal network of Caenorhabditis elegans, Morita S, Oshio K, Osana Y, Funabashi Y, Oka K, Kawamura K, Physica A, 298, 553 - 561, 2001 , Refereed
  • Does a Randomly Organized Electrical Circuit Function as a Neuronal System, Kawamura K, Funabashi Y, Morita S, Omata K, Oshio K, Osana Y, Oka K, Japanese Journal of Applied Physics, 40, 2095 - 2099, 2001 , Refereed
  • Native Response of C. elegans Encoded in Its Neuron Network, Funabashi Y, Kawamura K, Oshio K, Morita S, Osana Y, Akiyama E, Oka K, J Phys Soc Jpn, 70(4), 1154 - 1161, 2001 , Refereed
  • Analysis of Neural Connectivity of C.elegans using Random walker(jointly worked), 12th International C.elegans Meeting, 1999
  • Simulational study on neural network of C. elegans(CCE Program)(]G0001[), 54th Annual Meeting. The Physical Society of Japan, 1999, 1999
  • Bifurcation and Chaos of Current Oscillations in Semiconductors with NDC, Ken-ichi Oshio, Journal ot the Physical Society of Japan, 67(7), 2538 - 2545, 1998 , Refereed
  • Analysis of spike trains from Aplysia abdominal ganglia neurons, 36th Annual Meeting. The Biophysical Society of Japan, 1998, 1998
  • Simulational Study on Sb Pile-up at Si/SiO2 Interface, The 44th Spring Meeting, 1997 ; The Japan Society of Applied Physics and Related Societies, 1997
  • High-field Domains and Chaotic Current Oscillations in Semiconductor with NDC, TECHNICAL REPORT OF IEICE, ED96(210), 9 - 16, 1997

Conference Activities & Talks

  • Magnetically evoked EMGs in congenital hydrocephalic rats,   2000 03
  • Numerical study on excitatory and inhibitory pathways in neural network of C. elegans, Third east asian biophysics symposium EABS 2000,   2000 05 , Third east asian biophysics symposium EABS 2000
  • Changes in spinal cord function caused by injuries at different levels of the lumbar spinal cord,   2000 05
  • Prediction of brain and spinal cord damages in M-SHRSP by magnetically evopked EMGs,   2000 05
  • Classification of neurons with dynamical analysis with changing time resolution (DCT) method from multi-channel recording data,   2000 07
  • Neuron classification based on firing pattern with "Dynamical analysis with changing time resolution (DCT) method" from multi-channel recording data,   2000 09
  • Analysis on excitatory and inhibitory pathways in neural network of C. elegans III,   2000 09
  • The necessary factor for muscle contraction by magnetic stimulation,   2000 11
  • Impact spinal cord injury on magnetically evoked EMGs,   2000 11
  • Scanning microscopy of gastric vascular casts in hypertensive rats,   2001 03
  • Effects of magnetic stimulation on the smooth muscle contraction,   2001 05
  • Magnetically evoked EMGs in congenital hydrocephalus SHR,   2001 06
  • Pituitary vascular casts in hypertensive model rats,   2001 11
  • Effects of magnetic stimulation on the response of the isolated guinea pig vas deferens,   2002 03
  • Objective structured skill examination in phygiological student practice,   2002 03
  • Fatigue in muscular contraction caused by magnetic stimulation,   2002 05
  • Effects of magnetic field on the response of the isolated guinea pig vas deferens by capsaicin,   2002 07
  • Pathways from sensory neurons to motor neurons determined by McCulloch-Pitts algorithm, The third C. elegans meeting,   2002 08 , The third C. elegans meeting
  • Revision of synaptic connectivity database, The third japanese C. elegans meeting,   2002 08 , The third japanese C. elegans meeting
  • Effects of static magnetic field on the response of the isolated guinea pig vas deferens by capsaicin,   2002 08
  • PBL trial of the objective structured skill examination (OSSE) in PBL tutorial course, The 3rd Asian-Pacific Conference on PBL in Health Sciences,   2002 11 , The 3rd Asian-Pacific Conference on PBL in Health Sciences
  • The relation between pain and magnetic field in smooth muscle contraction,   2003 03
  • Behavioral characteristics during duration-discrimination task in the monkey,   2003 07
  • Effects of static magnetic field on the smooth muscle contraction by capsaicin pain model,   2003 11
  • Delay period activity fo dorsolateral prefrontal cortex during duration-discrimination task, The 31st NIPS International Symposium, Multidisciplinary Approaches to Sensorimotor Integration,   2004 03 , The 31st NIPS International Symposium, Multidisciplinary Approaches to Sensorimotor Integration
  • Anatomical data of synaptic connectivity of C. elegans are almost perfectly self-contained, 2004 East Asia Worm Meeting,   2004 07 , 2004 East Asia Worm Meeting
  • Relation of magnetically evoked EMGs and the spinal vascular lesions in M-SHRSP,   2004 06
    Summary:M-SHRSP
  • Functional roles of prefrontal cortex in time perception,   2004 08
  • Effects of static magnetic field for muscular contraction by pain,   2004 11
  • Neural mechanisms of monkey prefrontal cortex for time perception,   2004 12
  • The development of the objective strucured skill examination in Physiology education, XXXV International Congress of Physiological Sciences,   2005 04 , XXXV International Congress of Physiological Sciences
  • Phasic neuronal activity in the monkey striatum during duration discrimination task,   2005 05
  • Neuronal modulation in the monkey striatum related to duration discrimination task,   2005 07
  • Detection of rat spinal cord injuries by magnetic stimulation,   2005 07
  • Prophylactic effect and detection against stroke by magnetic stimulation,   2006 03
  • Prophylactic effect of repetitive magnetic stimulation against stroke in malignant stroke-prone spontaneously hypertensive rats,   2006 06
  • Delay period activity of the monkey striatum in duration discrimination task,   2006 07
  • Prophylactic effect of repetitive magnetic stimulation against stroke in malignant stroke-prone spontaneously hypertensive rats (M-SHRSP),   2006 12
  • Effects of transcranial magnetic stimulation on H-reflex in rats,   2007 03
  • Prophylactic effect of repetitive pulsed magnetic stimulation against stroke in malignant stroke-prone spontaneously hypertensive rats (M-SHRSP),   2007 06
  • Modulation of magnetically evoked H-reflex after moxibustion,   2007 06
  • Cue-period activity of monkey prefrontal neurons during a duration-discrimination task,   2007 09
  • Learning of leg position in crayfish using magnetic stimulation,   2008 03
  • Learning of leg position in crayfish with magnetic stimulation,   2008 06
  • Monkey striatal neurons encoded temporal information in duration discrimination task,   2008 07
  • Effects of isotonic contraction excised vas deferens of guinea-pigs under pain-related drugs, 16th International conference on Biomagnetism,   2008 08 , 16th International conference on Biomagnetism
  • Analgesia effects of static magnetic fields on muscular contraction,   2008 10
  • Effects of isolated crayfish heart by pulsed magnetic stimulation,   2009 05
  • Physiological effects of the upright sitting on the knees, 36th International congress of physiological sciences,   2009 07 , 36th International congress of physiological sciences
  • Response properties of monkey striatal neurons during a duration discrimination task,   2010 05
  • Cue response properties of monkey striatal neurons during duration discrimination task,   2010 09

Works

  • Simulational study on Neural Network of C. elegans
  • Analysis of spike data from Aplysia abdominal ganglion neurons

Misc

  • Current Oscillations Induced by Recombination Instability in Semiconductors, Journal of the Physical Society of Japan, 65, 5, 1490, 1499,   1996 , Refereed, 10.1143/JPSJ.65.1490
  • Non-Periodic Current Oscillations in the Gunn-Effect Device with the Impact-Ionization Effect, Journal of the Physical Society of Japan, 64, 5, 1823, 1836,   1995 , Refereed, 10.1143/JPSJ.64.1823
  • Chaotic Current Oscillations in the Gunn-Effect Device Under the dc and the rf Bias Voltages, Journal of the Physical Society of Japan, 62, 10, 3639, 3650,   1993 , Refereed, 10.1143/JPSJ.62.3639

Research Grants & Projects

  • Ministry of Education, Culture, Sports, Science and Technology, Grants-in-Aid for Scientific Research(基盤研究(C)), Functional roles of prefrontal cortex and striatum in duration discrimination, Kenichi OSHIO, The prefrontal cortex and the basal ganglia are considered to be related with temporal estimation. However, their functions remains unclear. We recorded single-unit activity from the brain regions while monkeys were performing a duration discrimination task. We found that, in the striatum, phasic(transient) activity with various time intervals from the cue onset, which was previously found in the prefrontal cortex. Furthermore, striatal neurons showed duration-responsive activity in the following delay periods.
  • Ministry of Education, Culture, Sports, Science and Technology, Grants-in-Aid for Scientific Research(基盤研究(C)), A study on neural mechanisms in time perception using duration discrimination tas, Ken-ichi OSHIO
  • Ministry of Education, Culture, Sports, Science and Technology, Grants-in-Aid for Scientific Research(基盤研究(C)), Temporal Information Processing in Prefrontal-Basal Ganglia Circuit, Masahiko INASE, We have been conducting neurophysiological experiments to reveal neuronal mechanisms for temporal information processing in the prefrontal-basal ganglia circuit. Monkeys were trained to perform a duration discrimination task. In the task, two visual cues were presented successively in different duration (0.2〜1.6 sec). Each cue presentation was followed by a 1-sec delay period. The subjects were instructed to choose a longer presented cue after the second delay period. Single-unit activity was recorded from the prefrontal cortex and the striatum while the monkeys were performing the task.Prefrontal neurons showed phasic activity during the first cue period. The activity had peak time around 800ms that was close to the midpoint between long and short cue duration. This activity might have functioned for filtering cue duration to discriminate between long and short cues. In the first delay period prefrontal neurons exhibited differential activity following long and short cues. In the neurons with preference for long cues the delay activity after longer cues was uniformly high regardless of cue duration, but that after shorter cues was uniformly low. This binary change in the delay activity indicates that the prefrontal cortex could represent cue duration categorically as long or short. Striatal neurons phasically responded during the first and second delay periods. Responses during the first delay period changed depending on the first cue duration. Activity of populations of these neurons correlated with the first cue duration positively or negatively. Responses during the second delay period differed between long-short and short-long trials. These findings suggest that striatal neurons could encode cue duration with monotonically changing responses and discrimination results between the two cue durations.
  • Ministry of Education, Culture, Sports, Science and Technology, Grants-in-Aid for Scientific Research(基盤研究(C)), Functional roles of cortico-basal gangila loops in conditional motor learning, Masahiko INASE, In order to examine functional roles of the prefrontal cortex in arbitrary visuomotor association, we recorded neuronal activity in the medial prefrontal cortex, area 9m, of a behaving monkey during conditional visuomotor learning. The monkey was presented a cueing visual stimulus, and following a delay period required to push, pull, or turn a manipulator according to the cue. Under the control condition three cues instructed the monkey to the three responses in a block of trials. After a few months of training the animal was familiar with these associations. Under the learning condition, two of the three familiar cues and one novel cue were presented in a block. The monkey needed to learn a new cue-response association by trial and error. Area 9m neurons responded to cue presentation. The Cue responses changed whether a cue was familiar or novel. A group of area 9m neurons responded to a novel cue, bur not to familiar ones. Other group of neurons responded to familiar cues, but not to a novel one. In a subgroup of these familiar cue-selective neurons the cue responses were enhanced under the learning condition compared to the control condition. These results suggest that cue familiarity is represented in area 9m activity and/or that the activity may be involved in action selection during the arbitrary visuomotor association learning.
  • Analysis of Multi-channel Recording Data in Central Nervou System
  • Study on higher brain function of the Monkey
  • Simulational Study on Neural Network of C. elegans
  • Study on Non-linear Phenomena in Semiconductors and The Applications
  • Data ayalysis of stock market
  • Analysis of Multi-recording data
  • Simulational Study on Neural Network of C. elegans