KINDAI UNIVERSITY


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Tomohiro Ogawa

Profile

FacultyDepartment of Biotechnology and Chemistry / General Education Division / Research Institute of Fundamental Technology for Next Generation
PositionLecturer
Degree
Commentator Guidehttps://www.kindai.ac.jp/meikan/506-ogawa-tomohiro.html
URL
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Last Updated :2019/09/04

Education and Career

Education

  •  - 2002 , Hiroshima University, Graduate School, Division of Natural Science, Department of Biological Science
  •  - 2000 , Hiroshima University, Faculty of Science, Department of biological Science

Academic & Professional Experience

  •   2016 09 ,  - 2017 08 , University of Southern California

Research Activities

Research Areas

  • Biological science, Molecular biology
  • Clinical internal medicine, Gastroenterology

Research Interests

  • Hepatology

Published Papers

  • Development of Capsular Fibrosis beneath the Liver Surface in Humans and Mice., Balog S, Li Y, Ogawa T, Miki T, Saito T, French SW, Asahina K, Hepatology (Baltimore, Md.), Jun. 2019 , Refereed
  • Isolation of a unique hepatic stellate cell population expressing integrin α8 from embryonic mouse livers., Ogawa T, Li Y, Lua I, Hartner A, Asahina K., Dev Dyn., 247(6), 867 - 881, Jun. 2018 , Refereed
  • Changes in sequences of core region, interferon sensitivity-determining region and interferon and ribavirin resistance-determining region of hepatitis C virus genotype 1 during interferon-alpha and ribavirin therapy, and efficacy of retreatment., Hepatol Res., 42(12), 1157 - 1167, Dec. 2012
  • MicroRNA-221/222 upregulation indicates the activation of stellate cells and the progression of liver fibrosis., Gut., 61(11), 1600 - 1609, Nov. 2012
  • Induction of microRNA-214-5p in human and rodent liver fibrosis., Fibrogenesis Tissue Repair., 5(1), 12, Aug. 2012
  • Down-regulation of cyclin E1 expression by microRNA-195 accounts for interferon-β-induced inhibition of hepatic stellate cell proliferation., J Cell Physiol., 226(10), 2535 - 2542, Oct. 2011
  • Close correlation of liver stiffness with collagen deposition and presence of myofibroblasts in non-alcoholic fatty liver disease., Hepatol Res., 41(9), 897 - 903, Sep. 2011
  • Promotion of liver and lung tumorigenesis in DEN-treated cytoglobin-deficient mice., Am J Pathol., 179(2), 1050 - 1060, Aug. 2011
  • Suppression of hepatic stellate cell activation by microRNA-29b., Biochem Biophys Res Commun., 412(1), 74 - 79, Aug. 2011
  • Usefulness of transient elastography for assessment of liver fibrosis in chronic hepatitis B: Regression of liver stiffness during entecavir therapy., Hepatol Res., 40(9), 853 - 861, Sep. 2010
  • A human-type non-alcoholic steatohepatitis model with advanced fibrosis in rabbits., Am J Pathol., 177(1), 153 - 165, Jul. 2010
  • Reversibility of fibrosis, inflammation, and endoplasmic reticulum stress in the liver of rats fed a methionine-choline-deficient diet., Lab Invest., 90(2), 245 - 256, Feb. 2010
  • Suppression of type I collagen production by microRNA-29b in cultured human stellate cells., Biochem Biophys Res Commun., 391(1), 316 - 321, Jan. 2010
  • Alpha-tocopheryl succinate induces rapid and reversible phosphatidylserine externalization in histiocytic lymphoma through the caspase-independent pathway., Mol Cell Biochem., 333(1-2), 137 - 149, Jan. 2010
  • Induction of tropomyosin during hepatic stellate cell activation and the progression of liver fibrosis., Hepatol Int., 3(2), 378 - 383, Jun. 2009
  • Effect of natural interferon alpha on proliferation and apoptosis of hepatic stellate cells., Hepatol Int., Apr. 2009
  • Pleiotrophin inhibits transforming growth factor beta1-induced apoptosis in hepatoma cell lines., Mol Carcinog., 47(10), 784 - 796, Oct. 2008
  • Attenuation of acute and chronic liver injury in rats by iron-deficient diet., Am J Physiol Regul Integr Comp Physiol., 294(2), R311 - R320, Feb. 2008

Conference Activities & Talks

  • Identification of integrin alpha8 as a specific surface marker for liver mesenchymal cells that negatively regulate maturation of liver progenitor cells in development, 20th Annual Pathology Conference,   2017 03
  • Induction of MicroRNA-221/222 in the Progression of Liver Fibrosis Caused by Chronic Hepatitis C Virus Infection, 10th JSH Single Topic Conference, “Hepatitis C: Best Practice Based on Science”,   2012 11 , 10th JSH Single Topic Conference, “Hepatitis C: Best Practice Based on Science”
  • Micro RNA profiling in activated stellate cells, 2012 ISBRA World Congress,   2012 09 , 2012 ISBRA World Congress
  • Role of CYGB in human HCC and in animal model of carcinogenesis,   2012 06
  • Tumor formation and the role of Cygb in DEN-mediated carcinogenesis,   2011 12
  • Changes in sequences of core region, ISDR and IRRDR of the HCV genotype 1 during and after interferon alpha and ribavirin therapy, and efficacy of retreatment., 62nd AASLD,   2011 11 , 62nd AASLD
  • Indication of the Activation of Stellate Cells and the Progression of Liver Fibrosis by MicroRNA-222, 62nd AASLD,   2011 11 , 62nd AASLD

Research Grants & Projects

  • Basic Science Research Program, Study on liver fibrosis mechanism