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MATSUMURA Koichiro

    Department of Medicine　Lecturer in Medical School
Last Updated :2024/04/25

Researcher Information

URL

Research funding number

  • 00728868

ORCID ID

J-Global ID

Research Interests

  • Cardiology   

Research Areas

  • Life sciences / Cardiology

Academic & Professional Experience

  • 2021/04 - Today  Kindai UniversityDepartment of Cardiology医学部講師
  • 2014/04 - 2021/03  Kansai Medical University循環器内科助教
  • 2012/04 - 2014/03  University of California, Los Angeles (UCLA)リサーチフェロー
  • 2009/04 - 2012/03  京都桂病院心臓血管センター内科医員
  • 2008/04 - 2009/03  関西医科大学附属病院第二内科後期レジデント
  • 2006/04 - 2008/03  関西医科大学附属病院初期レジデント

Education

  • 2017/03 -   Kansai Medical University

Published Papers

  • Kazuyoshi Kakehi; Masafumi Ueno; Takayuki Kawamura; Nobuhiro Yamada; Kuniaki Takahashi; Kosuke Fujita; Masakazu Yasuda; Koichiro Matsumura; Tatsuya Miyoshi; Kazuki Mizutani; Toru Takase; Genichi Sakaguchi; Gaku Nakazawa
    Journal of cardiology 2023/08 
    BACKGROUND: Early prediction of aorta-related events is important for determining subsequent treatment strategies in patients with acute aortic dissection. However, most studies evaluated long-term aortic growth rates by annual assessment. The purpose of our study was to determine whether the in-hospital growth rate of aortic volume was associated with aorta-related events. METHODS: We studied 116 patients with uncomplicated type B acute aortic dissection. We analyzed whether changes in aortic volume were associated with aorta-related events during a 5-year follow-up. According to the growth rate from admission to discharge, patients were divided into two groups: Increase >0 (aortic volume: n = 59, aortic diameter: n = 43) and Reduction ≤0 (aortic volume: n = 57, aortic diameter: n = 73) in maximum aortic diameter or aortic volume. The primary endpoint was the discriminative ability of the growth rate of aortic volume for aorta-related events. RESULTS: According to the evaluation of aortic volume changes, the Increase group had significantly higher aorta-related event rates than those in the Reduction group (49.2 % vs. 3.5 %, respectively; p < 0.001). Receiver operating characteristics analysis showed that the growth rate of aortic volume had a clearly useful discrimination, with an area under the curve of 0.84, whereas the discriminative ability of the growth rate of maximum aortic diameter was poor (area under the curve: 0.53). Multivariate analysis showed that the growth rate of aortic volume from admission to discharge was an independent predictor of aorta-related events (hazard ratio, 26.3; 95 % confidence interval, 2.04-286.49; p = 0.001). CONCLUSIONS: In-hospital evaluation of aortic volume was helpful to predict long-term aorta-related events in patients with uncomplicated type B acute aortic dissection.
  • Koichiro Matsumura; Takeshi Ijichi; Junko Morimoto; Kensuke Takabayashi; Mitsunori Miho; Keisuke Ueno; Eijiro Yagi; Toru Takase; Masafumi Ueno; Gaku Nakazawa
    Journal of cardiovascular pharmacology and therapeutics 28 10742484221146375 - 10742484221146375 2023/01 [Refereed]
     
    AIMS: In recent large trials, sacubitril/valsartan demonstrated favorable effects in patients with HF. However, many patients do not achieve the target dose of treatment. This study investigated the factors linked to up-titration of sacubitril/valsartan in patients with heart failure and preserved ejection fraction (HFpEF). METHODS: Using a multicenter retrospective database, 204 consecutive patients with HFpEF (left ventricular ejection fraction ≥ 40%) who were treated with sacubitril/valsartan between October 2020 and March 2022 were analyzed. Up-titration was defined as an increase in dosage above 24/26 mg BID beyond 12 weeks after the initiation of sacubitril/valsartan. RESULTS: Among the patients, 55% underwent up-titration, and 8% discontinued the drug. The baseline systolic blood pressure (SBP) was higher in patients with up-titration than in those with no up-titration; SBP values similar to that at baseline were observed between the 2 groups at 2 to 4 weeks and at 12 weeks after the commencement of sacubitril/valsartan treatment. The majority of those who discontinued sacubitril/valsartan did so because of hypotension. The multivariable logistic regression model showed that a history of hypertension, history of atrial fibrillation, baseline SBP, and baseline estimated glomerular filtration rate <60 mL/min/1.73 m2 were associated with sacubitril/valsartan up-titration. CONCLUSION: Approximately half of all patients did not undergo up-titration, and 8% of those with HFpEF discontinued the sacubitril/valsartan therapy. For aggressive up-titration and continuation of sacubitril/valsartan, patients with lower baseline SBP, renal dysfunction, absence of a history of hypertension, and presence of atrial fibrillation may require more careful monitoring.
  • Ohki Hayashi; Seishi Nakamura; Tetsuro Sugiura; Shun Hasegawa; Yoshiaki Tsuka; Nobuyuki Takahashi; Sanae Kikuchi; Koichiro Matsumura; Toshika Okumiya; Masato Baden; Ichiro Shiojima
    BMC nephrology 24 (1) 1 - 1 2023/01 [Refereed]
     
    BACKGROUND: The improvement of anaemia over time by erythropoiesis stimulating agent (ESA) is associated with better survival in haemodialysis patients. We previously reported that erythrocyte creatine content, a marker of erythropoietic capacity, was a reliable marker to estimate the effectiveness of ESA. The aim of this study was to examine the accuracy and clinical usefulness of erythrocyte creatine content to predict the improvement of anaemia in haemodialysis patients. METHODS: ESA dose was fixed 3 months prior to the enrollment and was maintained throughout the study period. Erythrocyte creatine content and haematologic indices were measured at baseline in 92 patients receiving maintenance haemodialysis. Haemoglobin was also measured 3 months after. Improvement of anaemia was defined as ≥ 0.8 g/dL change in haemoglobin from baseline to 3 months. RESULTS: Erythrocyte creatine content was significantly higher in 32 patients with improvement of anaemia compared to 60 patients with no improvement of anaemia (2.47 ± 0.74 vs. 1.57 ± 0.49 μmol/gHb, P = 0.0001). When 9 variables (erythrocyte creatine content, ESA dose, reticulocyte, haptoglobin, haemoglobin at baseline, serum calcium, intact parathyroid hormone, transferrin saturation and serum ferritin) were used in the multivariate logistic regression analysis, erythrocyte creatine emerged as the most important variable associated with the improvement of anaemia (P = 0.0001). The optimal cut-off point of erythrocyte creatine content to detect the improvement of anaemia was 1.78 μmol/gHb (Area under the curve: 0.86). Sensitivity and specificity of erythrocyte creatine content to detect the improvement of anaemia were 90.6% and 83.3%. CONCLUSION: Erythrocyte creatine content is a reliable marker to predict the improvement of anaemia 3 months ahead in patients receiving maintenance haemodialysis.
  • COVID禍から我々は何を学んだか? COVID-19パンデミックによる医療機関の受診控えと関連因子 長期化する感染の影響と今後の対策
    松村 光一郎; 田淵 貴大; 八木 英次郎; 高瀬 徹; 上野 雅史; 中澤 学; 中村 貴裕
    日本心臓病学会学術集会抄録 (一社)日本心臓病学会 70回 S14 - 6 2022/09
  • Koichiro Matsumura; Yasuhiro Kakiuchi; Takahiro Tabuchi; Toru Takase; Masafumi Ueno; Masahiro Maruyama; Kazuki Mizutani; Tatsuya Miyoshi; Kuniaki Takahashi; Gaku Nakazawa
    European journal of cardiovascular nursing 22 (4) 392 - 399 2022/07 [Refereed]
     
    AIM: Psychological distress is associated with poor prognosis in patients with cardiovascular disease (CVD). However, factors related to psychological distress in elderly patients with CVD is less understood. We aimed to investigate the rate of psychological distress in elderly patients with CVD in comparison with that of patients without CVD and to examine the clinical, socioeconomic, and lifestyle factors associated with this condition. METHODS AND RESULTS: Data from a nationwide population-based study in Japan of patients aged ≥ 60 years were extracted, and 1:1 propensity score matching was conducted of patients with and without CVD. Psychological distress was assessed using the K6 scale, on which a score ≥ 6 was defined as psychological distress. Of the 24,388 matched patients, the rate of psychological distress was significantly higher among patients with CVD compared to those without CVD (29.8% vs. 20.5%, p < 0.0001). The multivariate analysis revealed that female sex, comorbidities except hypertension, current smoking, daily sleep duration of < 6  h versus ≥ 8  h, home renter versus owner, retired status, having a walking disability, and lower monthly household expenditure were independently associated with psychological distress. Walking disability was observed in greatest association with psychological distress (odds ratio 2.69, 95% confidence interval 2.46-2.93). CONCLUSION: Elderly patients with CVD were more likely to have psychological distress compared to those without CVD. Multiple factors, including clinical, socioeconomic, and lifestyle variables, were associated with psychological distress. These analyses may help health care providers to identify high risk patients with psychological distress in a population of older adults with CVD.
  • 大学病院全体で取り組むACPの推進 学生教育・院内教育・各領域での実践・地域連携・市民啓発まで
    吉田 健史; 松村 光一郎; 三長 孝輔; 柏田 孝美; 藤野 崇; 森脇 裕子; 隅野 幸江; 仲里 美穂; 中川 和彦
    Palliative Care Research (NPO)日本緩和医療学会 17 (Suppl.) S.195 - S.195 2022/07
  • Koichiro Matsumura; Yasuhiro Kakiuchi; Takahiro Tabuchi; Toru Takase; Masahiro Maruyama; Masafumi Ueno; Gaku Nakazawa
    Journal of cardiology 80 (2) 133 - 138 2022/03 [Refereed]
     
    BACKGROUND: Cardiovascular disease and cancer share a number of risk factors and pathophysiologic mechanisms. Although risk management and early detection of cancer in patients with cardiovascular disease are important, preventive efforts in cardiology and oncology have been relatively disconnected. This study aimed to investigate the rate of cancer screening in a population of older adults with cardiovascular disease. METHODS: This study used data from the 2019 Comprehensive Survey of Living Conditions. Data on participants aged 60 years or older were extracted. The rate of cancer screening and cancer type were investigated between participants with and without cardiovascular disease. RESULTS: Of the 132,442 individuals, participants with cardiovascular disease had a significantly lower rate of cancer screening than those without cardiovascular disease [male: 4401 of 7972 participants (55.2%) vs. 33,744 of 52,106 participants (64.8%), p < 0.001; female: 2500 of 4984 participants (50.2%) vs. 41,319 of 67,380 participants (61.3%), p < 0.001]. The rate of cancer screening was significantly lower in participants with cardiovascular disease than in those without cardiovascular disease, regardless of cancer type, including gastric, colorectal, lung, breast, and gynecologic cancer screening. A history of cardiovascular disease was a negative factor for cancer screening (odds ratio 0.71, 95% confidence interval 0.67-0.74 in male participants; odds ratio 0.80, 95% confidence interval, 0.75-0.85 in female participants). CONCLUSIONS: The rate of cancer screening in elderly participants with cardiovascular disease was lower than that in participants without cardiovascular disease. Physicians should raise awareness regarding early cancer detection in patients with cardiovascular disease.
  • Shun Hasegawa; Seishi Nakamura; Tetsuro Sugiura; Yoshiaki Tsuka; Nobuyuki Takahashi; Koichiro Matsumura; Toshika Okumiya; Masato Baden; Ichiro Shiojima
    BMC nephrology 22 (1) 413 - 413 2021/12 [Refereed]
     
    BACKGROUND: One of the main causes of anaemia in patients with end-stage renal disease is relative deficiency in erythropoietin production. Eythropoiesis stimulating agent (ESA), a potent haematopoietic growth factor, is used to treat anaemia in haemodialysis patients. The effect of ESA is usually assessed by haematological indices such as red blood cell count, haemoglobin concentration and haematocrit, but erythrocyte indices do not provide information of the rapid change in erythropoietic activity. As erythrocyte creatine directly assess erythropoiesis, the aim of this study was to evaluate the effect of ESA in haemodialysis patients by measuring the erythrocyte creatine content. METHODS: ESA dose was fixed 3 months prior to the enrollment and was maintained throughout the entire study period. Erythrocyte creatine was measured with haematologic indices in 83 haemodialysis patients. Haemoglobin was also measured 3 months after. RESULTS: ESA dose (152.4 ± 62.9 vs. 82.2 ± 45.5 units/kg/week, P = 0.0001) and erythrocyte creatine (2.07 ± 0.73 vs. 1.60 ± 0.41 μmol/gHb, p = 0.0003) were significantly higher in 27 patients with haemoglobin <10 g/dL compared to 56 patients with haemoglobin ≥10 g/dL. There was a fair correlation between ESA dose and the concentration of creatine in the erythrocytes (r = 0.55, P < 0.0001). Increase in haemoglobin (>0.1 g/dL) was observed in 37 patients, whereas haemoglobin did not increase in 46 patients. Erythrocyte creatine levels were significantly higher in those patients with an increase in haemoglobin compared to those without (2.04 ± 0.64 vs. 1.52 ± 0.39 μmol/gHb, p < 0.0001). When 8 variables (ESA dose, erythropoietin resistance index, C-reactive protein, intact parathyroid hormone, iron supplementation, presence of anaemia, erythrocyte creatine and reticulocyte) were used in the multivariate logistic analysis, erythrocyte creatine levels emerged as the most important variable associated with increase in haemoglobin (Chi-square = 6.19, P = 0.01). CONCLUSION: Erythrocyte creatine, a useful marker of erythropoietic capacity, is a reliable marker to estimate ameliorative effectiveness of ESA in haemodialysis patients.
  • Hiroki Shibutani; Kenichi Fujii; Manabu Shirakawa; Kazutaka Uchida; Kiyofumi Yamada; Rika Kawakami; Takahiro Imanaka; Kenji Kawai; Kenta Hashimoto; Koichiro Matsumura; Hiroyuki Hao; Seiichi Hirota; Ichiro Shiojima; Shinichi Yoshimura
    The American journal of cardiology 156 123 - 128 2021/07 [Refereed]
     
    This study investigated whether optical frequency domain imaging (OFDI) can identify carotid artery vulnerable plaque characteristics, focusing on lipid-rich necrotic core (NC) and intraplaque hemorrhage (IPH). Fourteen patients scheduled for carotid endarterectomy underwent OFDI scan during preoperative angiography. Atherosclerotic plaque specimens obtained from carotid endarterectomy were cut every 3-4 mm into 4-μm transverse cross-sections and stained with standard methods. Each cross-section was matched with OFDI, and histologically classified into either fibrous, calcific, pathological intimal thickening (PIT), and NC. Of 75 histologic cross-sections, 6 were categorized as fibrous (8%), 18 as calcific (24%), 9 as PIT (12%), and 42 as NC (56%). Tissues categorized as NC had significantly higher OFDI signal attenuation rates than the other tissues (p <0.001), followed by PIT, calcific, and fibrous tissues. The receiver operating characteristic analysis indicated that attenuation rates of >0.023 and >0.031 predicted the presence of NC and IPH with high areas under the curve of 0.91 and 0.88, respectively. OFDI provides potential capability for the detection of NCs with IPH of carotid artery plaques by quantitatively analyzing the attenuation rate.
  • Hiroki Shibutani; Kenichi Fujii; Daiju Ueda; Rika Kawakami; Takahiro Imanaka; Kenji Kawai; Koichiro Matsumura; Kenta Hashimoto; Akira Yamamoto; Hiroyuki Hao; Seiichi Hirota; Yukio Miki; Ichiro Shiojima
    Atherosclerosis 328 100 - 105 2021/07 [Refereed]
     
    BACKGROUND AND AIMS: We developed a deep learning (DL) model for automated atherosclerotic plaque categorization using optical frequency domain imaging (OFDI) and performed quantitative and visual evaluations. METHODS: A total of 1103 histological cross-sections from 45 autopsy hearts were examined to compare the ex vivo OFDI scans. The images were segmented and annotated considering four histological categories: pathological intimal thickening (PIT), fibrous cap atheroma (FA), fibrocalcific plaque (FC), and healed erosion/rupture (HER). The DL model was developed based on pyramid scene parsing network (PSPNet). Given an input image, a convolutional neural network (ResNet50) was used as an encoder to generate feature maps of the last convolutional layer. RESULTS: For the quantitative evaluation, the mean F-score and IoU values, which are used to evaluate how close the predicted results are to the ground truth, were used. The validation and test dataset had F-score and IoU values of 0.63, 0.49, and 0.66, 0.52, respectively. For the section-level diagnostic accuracy, the areas under the receiver-operating characteristic curve produced by the DL model for FC, PIT, FA, and HER were 0.91, 0.85, 0.86, and 0.86, respectively, and were comparable to those of an expert observer. CONCLUSIONS: DL semantic segmentation of coronary plaques in OFDI images was used as a tool to automatically categorize atherosclerotic plaques using histological findings as the gold standard. The proposed method can support interventional cardiologists in understanding histological properties of plaques.
  • Hiroki Shibutani; Kenichi Fujii; Kenta Hashimoto; Satoshi Tsujimoto; Koichiro Matsumura; Munemitsu Otagaki; Shun Morishita; Ichiro Shiojima
    Heart and vessels 2021/04 [Refereed]
     
    Maximal hyperemia at the time of fractional flow reserve (FFR) measurement is generally induced by vasodilators, even when hyperemia at the onset of angina symptoms is caused by exercise stress. This study was designed to evaluate whether pharmacological hyperemia could be used as a substitute for exercise-induced hyperemia during FFR measurement. Twenty-two patients with angiographically intermediate stenosis in the left anterior descending artery (LAD) were prospectively enrolled. FFR measurements were repeated in the following two conditions while the pressure-wire was positioned in the same segment; (1) during pharmacological hyperemia induced by intracoronary administration of 2 mg nicorandil, (2) immediately after isotonic hand-grip exercise for 90 s (50% of maximum voluntary contraction) followed by intracoronary administration of 2 mg nicorandil. Isotonic hand-grip exercise increased systolic blood pressure (130 ± 19 versus 150 ± 22 mmHg, p < 0.001), heart rate (71 ± 11 versus 79 ± 13 bpm, p < 0.001), and cardiac output (5.1 ± 1.2 versus 5.9 ± 1.5 L/min, p < 0.001), which indicated an increased afterload on the left ventricle. After the hand-grip exercise, FFR significantly decreased from 0.86 ± 0.06 to 0.84 ± 0.06 (p < 0.001). A percent increase in systolic blood pressure and cardiac output after hand-grip exercise strongly correlated with ΔFFR (r = - 0.65, p < 0.001 and r = - 0.55, p < 0.001, respectively). An increase in cardiac output with hand-grip exercise during pharmacological hyperemia could induce an additional decrease in FFR for lesions located in the LAD.
  • Koichiro Matsumura; Wakana Teranaka; Masanao Taniichi; Munemitsu Otagaki; Hiroki Takahashi; Kenichi Fujii; Yoshihiro Yamamoto; Gaku Nakazawa; Ichiro Shiojima
    ESC heart failure 8 (3) 1819 - 1826 2021/03 [Refereed]
     
    AIMS: We aimed to investigate the differences in the prevalence, severity, and prognostic impact of malnutrition between patients with new-onset heart failure (HF) and worsening of chronic HF. METHODS AND RESULTS: In older (≥60 years) hospitalized patients with acute HF, malnutrition was assessed according to the Geriatric Nutritional Risk Index (GNRI). A score <92 was defined as malnutrition. The primary endpoint was a composite endpoint, including cardiac death or rehospitalization for HF. Among 210 patients, 37% (52/142) of patients with new-onset HF and 31% (21/68) of patients with worsening of chronic HF had malnutrition (P = 0.41). The GNRI classification was comparable between the two groups. Kaplan-Meier analysis revealed a significant difference in the incidence of the composite endpoint in patients with new-onset HF (GNRI < 92 vs. GNRI ≥ 92: 50% vs. 32%, P = 0.007), but not in patients with worsening of chronic HF (GNRI < 92 vs. GNRI ≥ 92: 67% vs. 68%, P = 0.91). The adjusted Cox proportional hazards model demonstrated that a GNRI of <92 was an independent prognostic factor for the composite endpoint in patients with new-onset HF only. CONCLUSIONS: Among older hospitalized patients with acute HF, the prevalence and severity of malnutrition were comparable between the two categories of patients. Malnutrition was an independent prognostic factor in patients with new-onset HF, while clinical prognosis was poor in patients with worsening of HF, irrespective of malnutrition. The prognostic impact of malnutrition differs between new-onset HF and worsening of chronic HF.
  • Munemitsu Otagaki; Kenichi Fujii; Koichiro Matsumura; Teppei Noda; Hiroki Shibutani; Kenta Hashimoto; Shun Morishita; Satoshi Tsujimoto; Yoshihiro Yamamoto; Haengnam Park; Kei Yoshioka; Ichiro Shiojima
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 2021/02 [Refereed]
     
    OBJECTIVES AND BACKGROUND: Although tissue protrusion (TP) between the stent struts after stent implantation has been implicate as a potential factor of stent failure, the incidence, natural history, and predictive factor of TP after stent implantation remains unclear. This prospective study evaluated the fate of TP after drug-eluting stent (DES) deployment using optical coherence tomography (OCT). METHOD AND RESULT: This study analyzed TP for 42 lesions after DES in which three serial OCTs, including preprocedure, postprocedure, and 1-month after the procedure were performed. TP was classified into the five groups: (a) persistent, (b) progressive, (c) healed, (d) regressive, and (e) late-acquired. Immediately after the procedure, 100 TPs in 37 lesions (88%) were identified. Of those, 53 (53%) were persistent, 3 (3%) were progressive, 20 (20%) were healed, and 24 (24%) were regressed at 1-month follow-up. Seven TPs in five patients (13%) were observed only at 1-month follow-up (late-acquired). CONCLUSION: In lesions with late-acquired TP, calcified nodule was identified as an underlying plaque morphology on preprocedural OCT. A serial OCT analysis found TP occurred not only immediately after DES implantation, but also 1-month after DES implantation.
  • Kensaku Wada; Kenichi Fujii; Keita Horitani; Hiroshi Kishimoto; Kenta Hashimoto; Hiroki Shibutani; Satoshi Tsujimoto; Koichiro Matsumura; Munemitsu Otagaki; Shun Morishita; Masayoshi Iwasaki; Ichiro Shiojima
    Heart and vessels 2021/02 [Refereed]
     
    BACKGROUND: Although the left coronary artery (LCA) has a flow profile in that most blood flow occurs during diastole rather than systole, the right coronary artery (RCA) has a flow pattern that is less diastolic dominant. This study assessed whether coronary pressure waveforms distal to stenoses with the same fractional flow reserve (FFR) was the same between the LCA and RCA. METHODS: A total of 347 vessels from 318 patients who underwent FFR measurements were included. Conventional FFR was calculated as the ratio of the mean coronary distal pressure (Pd) to the mean aortic pressure (Pa) at maximal hyperemia. The pressure drop ratios in systole (PDRsystole) and diastole (PDRdiastole) were calculated as the sum of (Pa minus Pd) divided by the sum of Pa at the intracoronary diastolic and systolic pressure phases, respectively. RESULTS: Analysis of covariance of the regression line of correlation between conventional FFR and PDRsystole revealed that the slope was significantly greater in the RCA than in the left anterior descending artery (LAD) and left circumflex artery (LCX) (-0.765, -0.578, and -0.589, p < 0.001). On the other hand, the regression line of correlation between conventional FFR and PDRdiastole found that the slope was significantly greater in the LAD and LCX than in the RCA (-1.349, -1.318, and -1.223, p < 0.001). CONCLUSIONS: The pressure waveform distal to the stenosis differs between the LCA and RCA. In the LCA, the decrease in diastolic pressure mainly contributed to the drop in FFR, whereas in the RCA, it was the decrease in systolic pressure.
  • Hiroki Shibutani; Kenichi Fujii; Rika Kawakami; Takahiro Imanaka; Kenji Kawai; Satoshi Tsujimoto; Koichiro Matsumura; Munemitsu Otagaki; Shun Morishita; Kenta Hashimoto; Hiroyuki Hao; Seiichi Hirota; Ichiro Shiojima
    The international journal of cardiovascular imaging 2021/01 [Refereed]
     
    The accurate identification of in-stent fibroatheroma by in vivo imaging is clinically important to preventing the late catch-up phenomenon after stent deployment. This study investigated the diagnostic accuracy of optical coherence tomography (OCT) for the detection of "in-stent fibroatheroma" following stent implantation. Fifty stented coronary arteries from the 31 autopsy hearts were examined to compare OCT and histological image findings. A histological in-stent fibroatheroma was defined as a neointima containing an acellular necrotic core generated by macrophage infiltration. OCT-derived in-stent fibroatheroma comprised a heterogeneous pattern with an invisible stent strut behind the low-signal-intensity region. A total of 122 matched OCT and histology cross-sections were evaluated. Using histological findings as the gold standard, the sensitivity, specificity, positive predictive value, and negative predictive value for OCT-derived in-stent fibroatheroma were 100%, 99%, 80%, and 100%, respectively. The only histological finding underlying the false-positive diagnosis of OCT-derived in-stent fibroatheroma was foam cell accumulation without a necrotic core on the neointimal surface. No false-negative diagnosis of OCT for in-stent fibroatheroma was apparent in this analysis. This study demonstrated the potential capability of OCT based on stent strut visualization behind low-signal-intensity regions to discriminate in-stent fibroatheroma from other neointimal tissues.
  • Koichiro Matsumura; Toshiji Iwasaka; Satoshi Mizuno; Ikuko Mizuno; Hikaru Hayanami; Kiyoshi Sawada; Junji Iwasaka; Kotaro Takeuchi; Toshimitsu Suga; Tetsuro Sugiura; Ichiro Shiojima
    Geriatrics (Basel, Switzerland) 6 (1) 2021/01 [Refereed]
     
    BACKGROUND: This study evaluated the effect of exercise training on body temperature and clarified the relationship between body temperature and body composition in the elderly. METHODS: In this retrospective cohort study, a total of 91 elderly participants performed aerobic and anaerobic exercise training twice a week for 2 years. Non-contact infrared thermometer and bioelectrical impedance analysis were performed at baseline and at 2 years. RESULTS: Mean age of study participants was 81.0 years. The participants were divided into two groups by baseline body temperature of 36.3 °C; lower body temperature group (n = 67) and normal body temperature group (n = 24). Body temperature rose significantly after exercise training in the lower body temperature group (36.04 ± 0.11 °C to 36.30 ± 0.13 °C, p < 0.0001), whereas there was no significant difference in the normal body temperature group (36.35 ± 0.07 °C to 36.36 ± 0.13 °C, p = 0.39). A positive correlation was observed between the amount of change in body temperature and baseline body temperature (r = -0.68, p < 0.0001). Increase in skeletal muscle mass was an independent variable related to the rise in body temperature by the multivariate logistic regression analysis (odds ratio: 4.77, 95% confidence interval: 1.29-17.70, p = 0.02). CONCLUSIONS: Exercise training raised body temperature in the elderly, especially those with lower baseline body temperature.
  • Hiroki Shibutani; Kenichi Fujii; Rika Kawakami; Takahiro Imanaka; Kenji Kawai; Satoshi Tsujimoto; Koichiro Matsumura; Munemitsu Otagaki; Shun Morishita; Kenta Hashimoto; Hiroyuki Hao; Seiichi Hirota; Ichiro Shiojima
    Journal of cardiology 2020/11 [Refereed]
     
    BACKGROUND: To date, there have been no data available regarding the diagnostic performance of optical frequency domain imaging (OFDI) for in vivo histological classification of atherosclerotic lesions. This study investigated whether OFDI can be used to diagnose and classify histological atherosclerotic lesions in the coronary artery by ex vivo histological examinations. METHODS: Three-hundred-fifteen histological cross-sections from 21 autopsy hearts were matched with the OFDI images. Histological cross-sections were classified into six categories: adaptive intimal thickening (AIT), pathological intimal thickening (PIT), fibrous cap atheroma (FA), fibrocalcific plaque (FC), calcified nodule, and healed erosion/rupture. The five observers with different years of experience in the interpretation of OFDI provided a single diagnosis for the OFDI scans of each cross-section according to the aforementioned six histological categories. The diagnostic accuracy and interobserver variability of lesion types for each OFDI observer were determined using histology as the gold standard. RESULTS: The overall agreement rates between OFDI and histopathologic diagnosis for OFDI observers 1-5 were 81%, 70%, 68%, 61%, and 50% (κ values of 0.75, 0.61, 0.58, 0.49, and 0.36), respectively. Although the diagnostic accuracy of OFDI for detecting AIT and FC was excellent for all five observers, the sensitivity, and positive predictive values of OFDI for detecting PIT and FA were low in proportion to years of experience. CONCLUSION: The diagnostic accuracy of atherosclerotic tissue properties from OFDI scans correlated with the observers' years of experience, especially when lesions contained lipid components.
  • Kenta Hashimoto; Kenichi Fujii; Hiroki Shibutani; Koichiro Matsumura; Satoshi Tsujimoto; Munemitsu Otagaki; Shun Morishita; Ichiro Shiojima
    The international journal of cardiovascular imaging 2020/10 [Refereed]
     
    This study evaluated whether intravascular ultrasound (IVUS) examination before rotational atherectomy (RA) can predict the optimal route of passage of the RA burr along the vessel. 30 patients with calcified lesions who underwent IVUS before and immediately after RA were enrolled. IVUS analyses were performed at the minimum lumen area (MLA) site and at 0.5 mm intervals. Each IVUS cross-section was divided into 4 quadrants around the center of the lumen, and pre- and post-RA IVUS cross-section images were merged. Of 1140 cross-sections, 498 (44%) contained debulked regions. When the guidewire and IVUS were located within the same quadrant, the debulked region were distributed within the same quadrant in 96% of cross-sections. The debulked region and the guidewire were distributed within the same quadrant in 81% and the debulked region and the IVUS in 72% of cross-sections, in case the guidewire and IVUS were located in different quadrants. When the guidewire and the IVUS was apart > 1.0 mm, the debulked regions were distributed within the same quadrant as the guidewire in 100% and the IVUS in 0% of cross-sections. The position of the guidewire rather than that of the IVUS catheter on pre-RA IVUS images could predict the course of the RA burr's passage, especially when the guidewire and IVUS catheter were located apart from each other.
  • Koichiro Matsumura; Toshika Okumiya; Tetsuro Sugiura; Nobuyuki Takahashi; Yoshihiro Yamamoto; Sanae Kikuchi; Kenichi Fujii; Munemitsu Otagaki; Ichiro Shiojima
    BMC nephrology 21 (1) 418 - 418 2020/09 [Refereed]
     
    BACKGROUND: The causes of anaemia in patients with end-stage renal disease include a relative deficiency in erythropoietin production and complex clinical conditions. We aimed to investigate the underlying mechanisms of anaemia in patients with end-stage renal disease who were undergoing maintenance dialysis by measuring erythrocyte creatine levels. METHODS: In a cross-sectional study, we evaluated 69 patients with end-stage renal disease who were receiving haemodialysis (n = 55) or peritoneal dialysis (n = 14). Erythrocyte creatine level, a quantitative marker of mean red blood cell (RBC) age, was measured. RESULTS: The mean RBC age was significantly shorter in the haemodialysis group than in the peritoneal dialysis group (47.7 days vs. 59.8 days, p < 0.0001), although the haemoglobin levels were comparable between the groups. A Spearman correlation coefficient analysis revealed that shortened RBC age positively correlated with transferrin saturation (r = 0.54), ferritin level (r = 0.47), and haptoglobin level (r = 0.39) but inversely related with reticulocyte (r = - 0.36), weekly doses of erythropoiesis-stimulating agents (ESAs; r = - 0.62), erythropoietin resistance index (r = - 0.64), and intradialytic ultrafiltration rate (r = - 0.32). CONCLUSIONS: Shortened RBC age was observed in patients who were receiving maintenance haemodialysis and was associated with iron deficiency, greater haptoglobin consumption, higher ESA requirements, and poor erythropoietin responsiveness, as well as with greater intradialytic fluid extraction.
  • Hiroshi Matsumoto; Koichiro Matsumura; Yoshihiro Yamamoto; Kenichi Fujii; Satoshi Tsujimoto; Munemitsu Otagaki; Shun Morishita; Kenta Hashimoto; Hiroki Shibutani; Tetsuro Sugiura; Ichiro Shiojima
    Journal of the American Heart Association 9 (19) e017315  2020/09 [Refereed]
     
    Background Muscle wasting is an important predictor of long-term outcome in patients with cardiovascular disease, but the prognostic value of muscle wasting in patients with non‒ST-segment‒elevation myocardial infarction is not established. The aim of this study is to investigate the prognostic value of muscle wasting, defined by psoas muscle mass index (PMI), in patients with non‒ST-segment‒elevation myocardial infarction. Methods and Results A total of 132 consecutive patients with non‒ST-segment‒elevation myocardial infarction were prospectively enrolled between 2015 and 2018. Primary end point was incidence of cardiovascular events including cardiovascular deaths, non-fatal myocardial infarction, or non-fatal stroke. Cross-sectional area of the psoas muscle at the L3 vertebral level was obtained by computed tomography and PMI was calculated. The median follow-up period was 2.4 years (interquartile range, 1.1-4.0 years). There were 45 cardiovascular events (34%) during the study periods. The optimal cutoff value of PMI to predict cardiovascular events was 772 mm2/m2, as assessed by receiver operating curve analysis. Patients with reduced PMI (PMI<772 mm2/m2) had significantly higher cardiovascular events than those with preserved PMI (PMI≥772 mm2/m2) (48% versus 21%; log-rank test P<0.001). Multivariate Cox proportional hazards model revealed that reduced PMI was a statistically significant predictor of cardiovascular events (hazard ratio, 3.30; 95% CI, 1.70-6.40; P<0.001). Conclusions Muscle wasting defined as PMI is a simple and useful objective marker to predict future cardiovascular outcome in patients with non‒ST-segment‒elevation myocardial infarction. Registration Information URL: https://www.umin.ac.jp/ctr/; Unique identifier: UMIN000013445.
  • Koichiro Matsumura; Wakana Teranaka; Hiroshi Matsumoto; Kenichi Fujii; Satoshi Tsujimoto; Munemitsu Otagaki; Shun Morishita; Kenta Hashimoto; Hiroki Shibutani; Yoshihiro Yamamoto; Ichiro Shiojima
    ESC heart failure 2020/09 [Refereed]
     
    AIMS: Loss of skeletal muscle mass is an important determinant associated with poor long-term prognosis in patients with acute decompensated heart failure (ADHF). However, limited evidence is available. This study investigated the prognostic value of the psoas muscle mass index (PMI) in patients with ADHF. METHODS AND RESULTS: A total of 210 consecutive patients aged ≥60 years with ADHF were enrolled using a prospective database between 2015 and 2017. Primary endpoint was incidence of cardiac death. Cross-sectional psoas muscle area at the L3 vertebral level was obtained by computed tomography, and PMI was calculated by height. Reduced PMI was defined as a PMI below the 25th sex-specific percentile. Patients were also classified by their left ventricular ejection fraction (EF) as having either heart failure with a reduced ejection fraction (HFrEF, EF < 50%) or heart failure with a preserved ejection fraction (HFpEF, EF ≥ 50%). The median follow-up period was 1.8 years. There were 44 cardiac deaths (21%) during the study period. Patients with reduced PMI had significantly higher cardiac death rates than those with preserved PMI (33% vs. 17%, log-rank test P = 0.006). In subgroup analysis, HFpEF patients with reduced PMI had significantly higher cardiac death rates than those with preserved PMI (38% vs. 16%, log-rank test P = 0.006); conversely, HFrEF patients had comparable cardiac death rates regardless of their PMI group (27% for reduced PMI vs. 18% for preserved PMI, log-rank test P = 0.24). Multivariate Cox proportional hazards model revealed that patients with reduced PMI had a 2.3-fold higher risk of cardiac death compared with patients with preserved PMI (95% confidence interval 1.23-4.42, P = 0.01). CONCLUSIONS: Reduced PMI helps to predict long-term outcome in patients with HFpEF but not HFrEF.
  • Hiromi Kin; Koichiro Matsumura; Yoshihiro Yamamoto; Kenichi Fujii; Munemitsu Otagaki; Hiroki Takahashi; Haengnam Park; Kei Yoshioka; Mitsuru Yokoi; Tetsuro Sugiura; Ichiro Shiojima
    ESC heart failure 7 (4) 1764 - 1770 2020/05 [Refereed]
     
    AIMS: Although tolvaptan has been reported to prevent worsening renal function (WRF) in patients with advanced acute heart failure (AHF), evidence regarding the effect of tolvaptan on renal function in patients with new-onset AHF is not available. This study aimed to investigate the renoprotective effect of tolvaptan in patients hospitalized with new-onset AHF. METHODS AND RESULTS: A total of 122 consecutive patients hospitalized with new-onset AHF between May 2015 and December 2018 were retrospectively evaluated. WRF was defined as an absolute increase in serum creatinine ≥0.3 mg/dL (≥26.4 μmol/L) within 48 h or a 1.5-fold increase in serum creatinine after hospitalization. The furosemide group (n = 75) and the tolvaptan add-on group (n = 47) were compared. The tolvaptan group consists of patients who received tolvaptan as an individual physicians' decision. The incidence of WRF was significantly lower in the tolvaptan add-on group (8.5%) than in the furosemide group (24.0%, P = 0.03). Multivariate logistic regression analysis revealed that tolvaptan treatment was an independent variable related to the prevention of WRF [odds ratio (OR), 0.20; 95% confidence interval (CI), 0.05-0.85]. Furthermore, subgroup analysis revealed a more favourable effect of tolvaptan in patients with serum creatinine ≥1.1 mg/dL on admission (OR, 0.23; 95% CI, 0.06-0.98) and an ejection fraction <50% (OR, 0.19; 95% CI, 0.04-0.90). CONCLUSIONS: A lower incidence of WRF was observed in patients with new-onset AHF who were treated with the tolvaptan add-on therapy, specifically those with left ventricular systolic dysfunction and renal impairment on admission.
  • Hiroki Shibutani; Kenichi Fujii; Rika Kawakami; Takahiro Imanaka; Kenji Kawai; Satoshi Tsujimoto; Koichiro Matsumura; Munemitsu Otagaki; Shun Morishita; Kenta Hashimoto; Seiichi Hirota; Ichiro Shiojima
    EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 2020/04 [Refereed]
     
    AIMS: This study evaluated the optical frequency domain imaging (OFDI) artifact of tangential signal dropout (TSD), which mimics the appearance of lipid-rich plaque and macrophage (Mø) infiltration. METHODS AND RESULTS: A total of 1,019 histological cross-sections from 23 autopsy hearts were matched with the corresponding OFDI images. Of those, 232 OFDI cross-sections that contained signal-poor regions with diffuse borders were classified as lipid-rich plaques. The angle θ was calculated between the OFDI beam that strikes the edge of the luminal surface of the low-intensity region and that which strikes the surface line of the low-intensity region. On histological evaluation, 182 (78%) cross-sections were classified as histologically lipidic/Mø infiltration, while the remaining 50 (22%) cross-sections as histologically non-lipidic/Mø infiltration. The angle θ was significantly smaller in the non-lipidic/Mø infiltration group than in the lipidic/Mø infiltration group (12±6° versus 37±14°, p<0.001). Receiver operating curve analysis revealed that the optimal cutoff value of the incident angle for predicting TSD was 23° with area under the curve 0.98. CONCLUSIONS: When the OFDI imaging beam strikes the tissue at an angle q<23°, TSD artifact could occur. To eliminate image misinterpretation, our findings suggest that the OFDI catheter geometry should be considered for the accurate diagnosis of lipid-rich plaques and Mø infiltration.
  • Koichiro Matsumura; Munemitsu Otagaki; Kenichi Fujii; Hiroki Shibutani; Shun Morishita; Kenta Hashimoto; Satoshi Tsujimoto; Yoshihiro Yamamoto; Tetsuro Sugiura; Ichiro Shiojima
    Resuscitation 147 67 - 72 2020/02 [Refereed]
     
    AIM: Acute myocardial infarction (AMI) is the leading cause of out-of-hospital cardiac arrest (OHCA). A highly predictive marker is needed to identify AMI in survivors of OHCA without ST-segment elevation because the appropriate indication for emergency coronary artery angiography in patients without ST-segment segment elevation has not been determined. Accordingly, the aim of this study was to elucidate the clinical significance of coronary artery calcification in identifying survivors of OHCA without ST-segment elevation who could benefit from emergency coronary artery angiography. METHODS: Survivors of OHCA without ST-segment elevation with no obvious extra-cardiac cause who underwent emergency computed tomography and coronary artery angiography were enrolled. Unstable coronary lesion was diagnosed using coronary artery angiography, and presence of coronary artery calcification and coronary artery calcium score were evaluated by non-contrast, non-electrocardiography gated computed tomography. RESULTS: Thirty of 100 consecutive survivors of OHCA were diagnosed to have unstable coronary lesion. Sensitivity and specificity of coronary artery calcification in identifying unstable coronary lesion were 87% and 60%, respectively. Multivariate logistic regression analysis revealed that coronary artery calcification was an independent predictor of unstable coronary lesion (odds ratio: 7.28, 95% confidence interval: 2.00-26.56, p < 0.001). CONCLUSION: Evaluation of coronary artery calcification by computed tomography is useful in identifying patients with unstable coronary lesion who could benefit from emergency coronary artery angiography among survivors of OHCA without ST-segment elevation on post-resuscitation electrocardiography.
  • Matsumura K; Sugiura T
    Cardiovascular Ultrasound 2019/12 [Refereed]
  • Shibutani H; Fujii K; Matsumura K; Otagaki M; Morishita S; Bando K; Motohiro M; Umemura S; Shiojima I
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 95 (6) E168-E174  1522-1946 2019/08 [Refereed]
     
    OBJECTIVES: This study evaluated whether the influence of lesion length on functional significance is similar between each target artery. BACKGROUND: In the presence of a similar moderate degree of stenosis, the fractional flow reserve (FFR) in the left anterior descending coronary artery (LAD) is more often <0.80 than in the other arteries. METHODS: A total of 221 lesions with intermediate stenosis on coronary angiography that underwent FFR measurement for the evaluation of myocardial ischemia were enrolled. Quantitative coronary angiographic analysis including percent diameter stenosis and lesion length was performed. The area under the receiver operating characteristics (ROC) curve was estimated for the best cutoff value as a predictor of FFR value of ≤0.80 for each coronary artery. RESULTS: Although lesion length was similar among the lesions with an FFR >0.80 at different locations, the mean lesion length was significantly longer for lesions in the right coronary artery (RCA) with an FFR ≤0.80 than for those in the LAD and left circumflex artery (13.4 ± 3.4 vs. 8.6 ± 3.1 vs. 12.0 ± 3.7 mm, p < .001). ROC analysis demonstrated that the optimal cutoff value of lesion length for predicting an FFR ≤0.80 was 10.0 mm in the LAD (0.56 area under the curve [AUC], 48% sensitivity, and 76% specificity), whereas 13.1 mm in the RCA (0.84 AUC, 67% sensitivity, and 93% specificity). CONCLUSIONS: The impact of lesion length on myocardial ischemia is different for each coronary artery. A longer lesion length is required in the RCA than in the LAD to achieve an FFR ≤0.80.
  • Matsumura K; Kin H; Otagaki M; Fujii K; Shibutani H; Yamamoto Y; Sugiura T; Shiojima I
    Circulation Reports 2434-0790 2019/08 [Refereed]
  • Otagaki M; Matsumura K; Kin H; Fujii K; Shibutani H; Matsumoto H; Takahashi H; Park H; Yamamoto Y; Sugiura T; Shiojima I
    Cardiovascular Drugs and Therapy Springer Science and Business Media {LLC} 33 (4) 435 - 442 0920-3206 2019/08 [Refereed]
     
    PURPOSE: Recent studies have shown that sodium glucose cotransporter 2 (SGLT2) inhibitors have a favorable effect on cardiovascular events in diabetic patients. However, the underlying mechanism associated with a favorable outcome has not been clearly identified. The purpose of this study was to investigate the effect of tofogliflozin, SGLT2 inhibitor, on systolic and diastolic cardiac function in patients with type 2 diabetes mellitus (T2DM). METHODS: We enrolled 26 consecutive T2DM out-patients on glucose-lowering drugs who initiated tofogliflozin and underwent echocardiography before and ≥ 6 months after tofogliflozin administration. During this period, we also enrolled 162 T2DM out-patients taking other glucose-lowering drugs as a control group. Propensity score analysis was performed to match the patient characteristics. As a result, 42 patients (tofogliflozin group 21 patients and control group 21 patients) were finally used for analysis. Left ventricular systolic function was assessed by measuring 2D-echocardiographic left ventricular ejection fraction (LVEF) and diastolic cardiac function by pulsed wave Doppler-derived early diastolic velocity (E/e'). RESULTS: There were no significant differences in patient characteristics and echocardiographic parameters at baseline. The change in LVEF from baseline to follow-up was 5.0 ± 6.9% in the tofogliflozin group and - 0.6 ± 5.5% in the control group; difference significant, p = 0.006. The change in E/e' was - 1.7 ± 3.4 in the tofogliflozin group and 0.7 ± 4.1 in the control group; difference significant, p = 0.024. CONCLUSIONS: In addition to conventional oral glucose-lowering drugs, additional tofogliflozin administration had a favorable effect on left ventricular systolic and diastolic function in patients with T2DM.
  • Matsumura K; Kin H; Matsuki R; Adachi K; Goda T; Yamamoto Y; Sugiura T; Shiojima I
    International Heart Journal 60 (4) 974 - 978 1349-3299 2019/07 [Refereed]
     
    A 72-year-old woman with hypertension, dyslipidemia, and diabetes mellitus presented to our hospital because of the sudden onset of chest pain. Emergency coronary angiography showed acute occlusion of the distal left anterior descending artery and coronary intervention with a drug-eluting stent was performed. Sudden cardiopulmonary arrest occurred on the sixth day of hospitalization, but coronary angiography showed no remarkable progression of the coronary artery diseases, including the site of stent implantation. An autopsy revealed that the cause of the sudden death was apical free wall rupture. In addition, the different timing of acute and sub-acute infarct findings were observed in the apical wall by histology, which indicated cardiac rupture was due to reinfarction at early phase of apical acute myocardial infarction. Although the rate of mechanical complications, including cardiac rupture, is decreasing in the era of primary coronary intervention, in addition to the well-known risk factors of cardiac rupture, the reinfarction of the culprit myocardial site in the early phase of acute myocardial infarction was considered as a possible risk factor of cardiac rupture.
  • Matsumura K; Morishita S; Taniguchi N; Takehana K; Takahashi H; Otagaki M; Yoshioka K; Yamamoto Y; Takagi M; Shiojima I
    Heart and vessels 34 (4) 607 - 615 1615-2573 2019/04 [Refereed]
     
    Inconsistent results have been reported concerning the effect of tolvaptan treatment on long-term prognostic outcomes in patients with acute decompensated heart failure (ADHF) and data are limited on prognostic factors affecting this patient population. We investigated prognostic factors influencing long-term clinical outcomes in patients with ADHF treated with tolvaptan in a real-world setting. A total of 263 consecutive patients hospitalized for ADHF and treated with tolvaptan were retrospectively enrolled. The patients were stratified into those who developed the combined event of cardiac death or rehospitalization for worsening heart failure within 1 year (n = 108) and those who were free of this combined event within 1 year (n = 155). Adjusted multivariate Cox proportional hazards model revealed that change in serum sodium level between pre-treatment and 24 h after tolvaptan administration [hazard ratio (HR) 0.913, 95% confidence interval (CI) 0.841-0.989, p = 0.025] and the time taken for tolvaptan initiation from admission (HR 1.043, 95% CI 1.009-1.074, p = 0.015) were independent predictors of combined event occurrence within 1 year. Moreover, change in serum sodium level > 1 mEq/L between pre-treatment and 24 h after administration and initiation of tolvaptan < 5 days after admission correlated significantly with the incidence of the combined event (log-rank test p = 0.003 and p = 0.002, respectively). In conclusion, increased serum sodium level early after administration and early initiation of tolvaptan are possibly useful for assessing the long-term prognosis after tolvaptan treatment in patients with ADHF.
  • Nagashima K; Hiro T; Fukamachi D; Okumura Y; Watanabe I; Hirayama A; Tanaka M; Tanaka T; Takamisawa I; Taguchi I; Sato A; Aonuma K; Fukamizu S; Nakada A; Watanabe A; Amioka N; Suzuki Y; Matsumoto N; Koizumi J; Kumagai K; Naya M; Higuchi Y; Naito Y; Masuyama T; Kawamura M; Tsunoda R; Suzuki S; Ishii H; Murohara T; Shimizu T; Takeishi Y; Shiina K; Yamashita J; Imamura T; Sumitomo N; Noguchi T; Aso T; Furukawa K; Yamauchi Y; Okishige K; Sakata K; Yamagishi M; Shimizu S; Ohno M; Sugano T; Matsumura K; Matsumoto K; Ozaki K; Hayashidani S; Meno H; Iwata A; Higuma T; Tomita H; Yoshino H; Taniai S; Shishido K; Murakami M; Negishi K; Nii M; Wakatsuki D; Suzuki H; Motoike Y; Ozaki Y; Nakazato J; Hayashi H; Higuchi S; Shoda M
    European Heart Journal - Cardiovascular Imaging 21 (2) 222 - 230 2047-2412 2019/04 [Refereed]
     
    AIMS: Anomalous origin of the coronary artery (AOCA) with an inter-arterial course (IAC) between the great vessels poses a risk for a life-threatening cardiovascular event. We assessed, in a registry-based study, the clinical features, treatment strategies, and prognoses of life-threatening cardiovascular events ensuant to AOCA. METHODS AND RESULTS: Included were 65 AOCA patients (48 men/17 women, aged 41 ± 23 years) from 40 clinical centres who had experienced sudden cardiac arrest (SCA) (n = 30), acute myocardial infarction (AMI) (n = 5), angina (n = 23), or syncope (n = 7). The anomalous vessel was the right coronary artery in 72% of patients and left coronary artery in 28%; the ostium was slit-like in 42%. Coronary luminal narrowing ≥75% was absent in patients with SCA or syncope (86% and 57%, respectively), but occlusion or narrowing was seen in those with AMI (100%) or angina (52%). Age ≤40 years, male sex, sporting activity, absence of prodromal symptoms, acutely angled (≤30°) take-off from the aorta, and absence of luminal narrowing of the IAC segment were associated with SCA in this patient group. Coronary vasospasm was inducible in 12 of 17 patients without coronary narrowing. Management included surgical revascularization (n = 26) percutaneous coronary intervention (n = 9), and medical treatment (n = 26). Four SCA patients died while hospitalized; no others died during the median 5.0 (range, 1.8-7.0)-year follow-up period. CONCLUSIONS: In patients with AOCA, age ≤40 years, male sex, sporting activity, and an acute take-off angle appear to be risk factors for SCA. Appropriate management can be beneficial. Confirmation in a large-scale study is warranted.
  • Otagaki M; Matsumura K; Fujii K; Kin H; Yamamoto Y; Shiojima I
    Circulation journal : official journal of the Japanese Circulation Society 83 (9) 1971 - 1971 1346-9843 2019/03 [Refereed]
  • Koichiro Matsumura; Hiroshi Matsumoto; Yoshihiro Hata; Takanao Ueyama; Tatsuomi Kinoshita; Shintaro Kuwauchi; Yoshiyuki Takami; Kohei Kawazoe; Ichiro Shiojima
    INTERNAL MEDICINE JAPAN SOC INTERNAL MEDICINE 55 (1) 55 - 58 0918-2918 2016 [Refereed]
     
    Cardiac events associated with congenital coronary abnormalities are rare but potentially life-threatening in a young population. Most of these patients are not diagnosed before their initial cardiac event. Amongst such coronary artery anomalies, sudden death is frequently seen in an anomalous origination of a coronary artery from the opposite sinus. We herein present the case of a patient who presented with sudden cardiac arrest associated with an anomalous right coronary artery originating from the left sinus of Valsalva. Surgical treatment was selected because there was evidence of reversible ischemia based on the findings of a stress test.
  • Koichiro Matsumura; Rubine Gevorgyan; Daniel Mangels; Reza Masoomi; Mohammad Khalid Mojadidi; Jonathan Tobis
    CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS WILEY-BLACKWELL 84 (3) 455 - 463 1522-1946 2014/09 [Refereed]
     
    Objectives: To assess the effective closure rate among devices used for transcatheter patent foramen ovale (PFO) closure, and to discuss the management of patients with large residual shunts. Background: Several devices are used off-label for transcatheter closure of a PFO in the United States. The rate of residual shunting after PFO closure varies by device. Failure of effective closure poses risk of a recurrent cerebrovascular event, persistent migraine, or recurrent orthodeoxia. Methods: Patients who underwent PFO closure in the Cardiac Catheterization Laboratory at UCLA between 2001 and 2013 and had baseline and adequate follow-up transcranial Doppler studies following device placement were enrolled in the study. Results: Of 167 patients whose records were analyzed, effective PFO closure occurred in 90% (150/167) of patients. The highest effective closure rate was with the Amplatzer Septal Occluder (ASO; 100%), followed by the Amplatzer Cribriform (93%), Gore Helex (90%), Amplatzer PFO (86%), and CardioSEAL (86%) device. The highest rate of residual shunting was observed after placement of the 30-mm Gore Helex device (55%). Of the 17 patients with a residual shunt, three required a repeat PFO closure procedure due to a significant residual shunt associated with recurrent pulmonary emboli or profound orthodeoxia. All three patients received an ASO which successfully closed the residual shunt. Conclusions: Transcatheter PFO closure has a high success rate, but a moderate residual shunt occurs in about 10% of cases. The observed incidence of residual shunting after PFO closure is significantly larger with the 30-mm Helex device. (C) 2014 Wiley Periodicals, Inc.
  • 江島恵美子; 松村光一郎; 林典行; 柴田兼作; 溝渕正寛; 舩津篤史; 小林智子; 中村茂
    日本心血管インターベンション治療学会誌 5 (3) 193 - 197 1884-0027 2013/11
  • Koichiro Matsumura; Rubine Gevorgyan; William M. Suh; Jonathan Tobis
    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY ELSEVIER SCIENCE INC 62 (18) B195 - B195 0735-1097 2013/10 [Refereed]
  • Koichiro Matsumura; Rubine Gevorgyan; Jonathan Tobis
    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY ELSEVIER SCIENCE INC 62 (18) B206 - B206 0735-1097 2013/10 [Refereed]
  • 鈴木幸園; 松村光一郎; 江島恵美子; 中村茂; 大石享; 山原康裕
    乙訓医学会集録 22nd 72 - 78 2013/03
  • Tomohito Saito; Yukihito Saito; Koichiro Matsumura; Yu Tsubota; Tomohiro Maniwa; Hiroyuki Kaneda; Ken-Ichiro Minami; Noriko Sakaida; Yoshiko Uemura; Gen Kawa; Nae Yamamoto; Yoshimitsu Fujii; Kazumasa Isobe; Yasushi Kawakami; Tadashi Matsuda; Kazuhiro Takekoshi
    Endocrine Journal 56 (3) 451 - 458 0918-8959 2009 [Refereed]
     
    Recently, nuclear genes encoding two mitochondrial complex II subunit proteins, SDHD and SDHB, have been found to be associated with the development of familial pheochromocytomas and paragangliomas (hereditary pheochromocytoma/paraganglioma syndrome: HPPS). Growing evidence suggests that the mutation of SDHB is highly associated with abdominal paraganglioma and the following distant metastasis (malignant paraganglioma). In the present study, we report the case of a novel SDHB mutation (L157X) in a Japanese patient with abdominal paraganglioma following malignant lung metastasis. In addition, we identified an asymptomatic carrier of the SDHB mutation in this family.
  • 堀越幹人; 宮坂陽子; 拝殿未央; 山本哲史; 前羽宏史; 五十野剛; 杉山千晶; 小倉常敬; 妹尾健; 松村光一郎; 中東三聖; 横江洋之; 万木孝富; 岩坂壽二
    Heart Nursing メディカ出版 20 (11) 1138 - 1143 0914-2819 2007/11

MISC

  • Salt Restriction Risks in Heart Failure Patients(タイトル和訳中)
    Funauchi Yohei; Takase Toru; Matsumura Koichiro; Ueno Masafumi; Nakazawa Gaku  日本循環器学会学術集会抄録集  87回-  OE59  -2  2023/03
  • Prognostic Impact of TIMI Frame Count in Patients with Dilated Cardiomyopathy(タイトル和訳中)
    Kawamura Takayuki; Matsumura Koichiro; Funauchi Yohei; Soejima Naoko; Okune Mana; Kakehi Kazuyoshi; Yasuda Masakazu; Mizutani Kazuki; Ueno Masafumi; Nakazawa Gaku  日本循環器学会学術集会抄録集  87回-  PE52  -1  2023/03
  • Association of Lifestyle Changes and Weight Gain in Adult Population during the COVID-19 Pandemic(タイトル和訳中)
    松村 光一郎; 八木 英次郎; 高林 健介; 伊地知 健; 長谷川 実咲; 大西 教平; 筧 和剛; 河村 尚幸; 上野 雅史; 中澤 学  日本循環器学会学術集会抄録集  87回-  OJ40  -2  2023/03
  • COVID禍から我々は何を学んだか? COVID-19パンデミックによる医療機関の受診控えと関連因子 長期化する感染の影響と今後の対策
    松村 光一郎; 田淵 貴大; 八木 英次郎; 高瀬 徹; 上野 雅史; 中澤 学; 中村 貴裕  日本心臓病学会学術集会抄録  70回-  S14  -6  2022/09
  • 大学病院全体で取り組むACPの推進 学生教育・院内教育・各領域での実践・地域連携・市民啓発まで
    吉田 健史; 松村 光一郎; 三長 孝輔; 柏田 孝美; 藤野 崇; 森脇 裕子; 隅野 幸江; 仲里 美穂; 中川 和彦  Palliative Care Research  17-  (Suppl.)  S.195  -S.195  2022/07
  • 松村 光一郎; 寺中 若菜; 松本 宙士; 太田垣 宗光; 山本 克浩; 杉浦 哲朗; 塩島 一朗  福田記念医療技術振興財団情報  (34)  111  -122  2021/12
  • SGLT2阻害薬が心機能に与える影響とその潜在的メカニズム
    松村 光一郎  日本循環器学会学術集会抄録集  85回-  LS16  -1  2021/03
  • Influence of Different Physiological Hemodynamics on Fractional Flow Reserve in the Left Coronary Artery and Right Coronary Artery(和訳中)
    Wada Kensaku; Fujii Kenichi; Shibutani Hiroki; Hashimoto Kenta; Morishita Shun; Otagaki Munemitsu; Matsumura Koichiro; Tsujimoto Satoshi; Kishimoto Hiroshi; Iwasaki Masayoshi; Shiojima Ichiro  日本循環器学会学術集会抄録集  85回-  OE065  -3  2021/03
  • Nodular Calcification Does not Always Have a Convex Shape of the Luminal Surface: Histopathological Validation of Optical Frequency Domain Imaging(和訳中)
    Hashimoto Kenta; Fujii Kenichi; Kawakami Rika; Shibutani Hiroki; Imanaka Takahiro; Kawai Keiji; Tsujimoto Satoshi; Matsumura Koichiro; Otagaki Munemitsu; Morishita Shun; Shiojima Ichiro  日本循環器学会学術集会抄録集  85回-  OE031  -4  2021/03
  • Frequency and Distribution of Sheet and Nodular Calcification in Human Coronary Arteries in Japanese Patients: An Autopsy Study(和訳中)
    Hashimoto Kenta; Fujii Kenichi; Kawakami Rika; Shibutani Hiroki; Imanaka Takahiro; Kawai Keiji; Tsujimoto Satoshi; Matsumura Koichiro; Otagaki Munemitsu; Morishita Shun; Shiojima Ichiro  日本循環器学会学術集会抄録集  85回-  OE031  -5  2021/03
  • Importance of Quantitative and Qualitative Assessments of Skeletal Muscle in Older Patients with Acute Heart Failure(和訳中)
    Matsumura Koichiro; Fujii Kenichi; Yamamoto Yoshihiro; Otagaki Munemitsu; Morishita Shun; Hashimoto Kenta; Shibutani Hiroki; Tsujimoto Satoshi; Shiojima Ichiro  日本循環器学会学術集会抄録集  85回-  OE099  -5  2021/03
  • Validation of the Academic Research Consortium High Bleeding Risk Criteria for Patients with Aortic Stenosis(和訳中)
    Tsujimoto Satoshi; Fujii Kenichi; Shibutani Hiroki; Hashimoto Kenta; Morishita Shun; Otagaki Munemitsu; Matsumura Koichiro; Shiojima Ichiro  日本循環器学会学術集会抄録集  85回-  OE139  -3  2021/03
  • 経食道エコーで過小評価したバルーン大動脈弁形成術後の急性大動脈弁逆流
    辻本 悟史; 渋谷 裕樹; 橋本 健太; 田中 真沙美; 森下 瞬; 松村 光一郎; 太田垣 宗光; 藤井 健一; 塩島 一朗  日本心血管インターベンション治療学会抄録集  29回-  637  -637  2021/02
  • Sarcopenia predicts poor long-term prognosis in patients with non-ST-segment elevation myocardial infarction(和訳中)
    松村 光一郎; 松本 宙士; 太田垣 宗光; 藤井 健一; 朴 幸男; 山本 克浩; 塩島 一朗  日本心血管インターベンション治療学会抄録集  29回-  1089  -1089  2021/02
  • The Prevalence and Natural History of Tissue Protrusion After Drug-eluting Stent Implantation: A Serial Optical Coherence Tomography Study(和訳中)
    太田垣 宗光; 藤井 健一; 松村 光一郎; 朴 幸男; 山本 克浩  日本心血管インターベンション治療学会抄録集  29回-  1343  -1343  2021/02
  • The Optical Frequency Domain Imaging Artifact of Tangential Signal Dropout Mimicking the Appearance of Lipid-rich Plaques: An Ex-Vivo Imaging Study(和訳中)
    澁谷 裕樹; 藤井 健一; 川上 りか; 今仲 崇裕; 河合 健志; 辻本 悟史; 松村 光一郎; 太田垣 宗光; 森下 瞬; 橋本 健太; 廣田 誠一; 塩島 一朗  日本心血管インターベンション治療学会抄録集  29回-  1344  -1344  2021/02
  • Predictive Values of the Debulking Segment by Rotational Atherectomy on Pre-Procedural Intravascular Ultrasound Imaging(和訳中)
    橋本 健太; 藤井 健一; 辻本 悟史; 森下 瞬; 渋谷 裕樹; 松村 光一郎; 太田垣 宗光; 元廣 将之; 杉田 洋; 田中 真沙美  日本心血管インターベンション治療学会抄録集  29回-  1360  -1360  2021/02
  • 高齢者に対する2年間の短時間機能訓練の効果 体温に注目して
    武内 孝太郎; 岩坂 壽二; 松村 光一郎; 岩坂 潤二; 菅 俊光; 清水 祐司; 岡本 博美; 能口 司; 早浪 光; 澤田 清; 水野 郁子; 水野 智志  日本臨床生理学会雑誌  50-  (5)  173  -178  2020/12
  • Shibutani Hiroki; Fujii Kenichi; Hashimoto Kenta; Morishita Shun; Tanaka Masami; Otagaki Munemitsu; Sugita Hiroshi; Matsumura Koichiro; Tsujimoto Satoshi; Umemura Shigeo; Motohiro Masayuki; Shiojima Ichiro  日本循環器学会学術集会抄録集  84回-  OE9  -2  2020/07
  • Prediction of the Debulking Segment by Rotational Atherectomy on Pre-Procedural Intravascular Ultrasound Imaging(和訳中)
    Hashimoto Kenta; Fujii Kenichi; Tsujimoto Satoshi; Morishita Shun; Shibutani Hiroki; Matsumura Koichiro; Otagaki Munemitsu; Motohiro Masayuki; Umemura Shigeo; Sugita Hiroshi; Tanaka Masami; Shiojima Ichiro  日本循環器学会学術集会抄録集  84回-  OE36  -3  2020/07
  • The Fate of Tissue Protrusion after Drug-Eluting Stents: A Serial Optical Coherence Tomography-Based Natural History Study(和訳中)
    Otagaki Munemitsu; Fujii Kenichi; Matsumura Koichiro; Shibutani Hiroki; Hashimoto Kenta; Morishita Shun; Tsujimoto Satoshi; Yoshioka Kei; Park Haeng; Yamamoto Yoshihiro; Shiojima Ichiro  日本循環器学会学術集会抄録集  84回-  OE115  -1  2020/07
  • Potential Mechanism of Early In-stent Restenosis of Drug-eluting Stent after Rotational Atherectomy: A Serial Intravascular Ultrasound Study(和訳中)
    Morishita Shun; Fujii Kenichi; Shibutani Hiroki; Hashimoto Kenta; Tanaka Masami; Otagaki Munemitsu; Sugita Hiroshi; Matsumura Koichiro; Tsujimoto Satoshi; Umemura Shigeo; Motohiro Masayuki; Shiojima Ichiro  日本循環器学会学術集会抄録集  84回-  PE25  -6  2020/07
  • 血液透析による血管内溶血の影響と臨床的意義
    松村 光一郎; 奥宮 敏可; 杉浦 哲朗; 菊池 早苗; 藤井 健一; 山本 克浩; 高橋 延行; 塩島 一朗  日本内科学会雑誌  109-  (Suppl.)  208  -208  2020/02
  • 院外心停止患者における急性心筋梗塞早期スクリーニングのための冠動脈石灰化スコアの有用性
    松村 光一郎; 山本 克浩; 杉浦 哲朗; 塩島 一朗  日本心臓病学会学術集会抄録  67回-  O  -102  2019/09
  • 初回急性心不全患者に対するトルバプタンの腎保護効果
    松村 光一郎; 山本 克浩; 杉浦 哲朗; 塩島 一朗  日本心臓病学会学術集会抄録  67回-  O  -226  2019/09
  • 薬剤溶出性ステント留置後のステント内への組織逸脱の発生率、自然史、予測因子について
    太田垣 宗光; 藤井 健一; 松村 光一郎; 朴 幸男; 山本 克浩  日本心血管インターベンション治療学会抄録集  28回-  [MO7  -003]  2019/09
  • 院外心停止患者における冠動脈カルシウム量の有用性(The Utility of the Coronary Artery Calcium Volume in Patients with Out-of-Hospital Cardiac Arrest)
    Matsumura Koichiro; Matsumoto Hiroshi; Yamaguchi Mayuko; Takahashi Hiroki; Yokoi Mitsuru; Otagaki Munemitsu; Yoshio Takuro; Yoshioka Kei; Yoh Masue; Park Haeng; Yamamoto Yoshihiro; Takagi Masahiko; Shiojima Ichiro  日本循環器学会学術集会抄録集  83回-  PE16  -4  2019/03
  • 心イベントを伴う冠動脈異常起始 臨床的プロフィール、管理および長期転帰(Anomalous Origin of the Coronary Artery with Cardiac Events: Clinical Profile, Management and Long-Term Outcome)
    Nagashima Koichi; Fukamachi Daisuke; Hirayama Atsushi; Tanaka Masashi; Sato Akira; Aonuma Kazutaka; Fukamizu Seiji; Nakada Akihiro; Suzuki Yasuyuki; Matsumoto Naoya; Koizumi Junichi; Kumagai Kazuya; Naya Masanao; Higuchi Yoshiharu; Furukawa Kojiro; Yamauchi Yasuteru; Okishige Kaoru; Sakata Kenji; Yamagishi Masakazu; Shimizu Shigeo; Ohno Masakazu; Sugano Teruyasu; Matsumura Koichiro; Matsumoto Kensuke; Ozaki Kazuyuki; Hayashidani Shunji; Meno Hiroshi; Taguchi Isao; Iwata Atsushi; Higuma Takumi; Tomita Hirofumi; Yoshino Hideaki; Taniai Seiichi; Naito Yoshiro; Kawamura Mitsuharu; Shishido Koki; Murakami Masato; Negishi Koji; Nii Masaki; Tsunoda Ryusuke; Suzuki Susumu; Ishii Hideki; Wakatsuki Daisuke; Suzuki Hiroshi  日本循環器学会学術集会抄録集  82回-  OE73  -6  2018/03
  • 安達賢太郎; 松本宙士; 山口眞由子; 横井満; 太田垣宗光; 高橋広季; 吉尾拓朗; 松村光一郎; 野田哲平; 吉岡慶; 楊培慧; 朴幸男; 高木雅彦; 山本克浩; 塩島一朗  日本循環器学会近畿地方会(Web)  126th-  KINKI126,B06 (WEB ONLY)  2018
  • 金宏美; 太田垣宗光; 松本宙士; 高橋広季; 山口眞由子; 吉尾拓朗; 横井満; 松村光一郎; 吉岡慶; 朴幸男; 楊培慧; 高木雅彦; 山本克浩; 塩島一朗  日本循環器学会近畿地方会(Web)  126th-  KINKI126,C06 (WEB ONLY)  2018
  • 糖尿病はST部分上昇型心筋梗塞高齢患者におけるno-reflowおよび2年心臓死亡率の増加と関連する(Diabetes Mellitus is Associated with Increase of No-reflow and 2-year Cardiac Mortality in Elderly Patients with ST-segment Elevation Myocardial Infarction)
    Matsumura Koichiro; Yokoi Mitsuru; Otagaki Munemitsu; Yoshio Takuro; Noda Teppei; Yoshioka Kei; Ueyama Takanao; Sakuma Takao; Park Haeng; Iharada Yoshiji; Yamamoto Yoshihiro; Shiojima Ichiro  日本循環器学会学術集会抄録集  81回-  PE  -656  2017/03
  • 堀茜衣; 太田垣宗光; 横井満; 吉尾拓朗; 松村光一郎; 野田哲平; 吉岡慶; 上山敬直; 朴幸男; 山本克浩; 塩島一朗  日本循環器学会近畿地方会(Web)  123rd-  KINKI123,D27 (WEB ONLY)  2017
  • 横井満; 朴幸男; 太田垣宗光; 吉尾拓朗; 松村光一郎; 野田哲平; 吉岡慶; 上山敬直; 山本克浩; 塩島一朗  日本循環器学会近畿地方会(Web)  123rd-  KINKI123,E18 (WEB ONLY)  2017
  • 金宏美; 太田垣宗光; 山口眞由子; 横井満; 高橋広季; 吉尾拓朗; 松村光一郎; 野田哲平; 吉岡慶; 上山敬直; 朴幸男; 山本克浩; 塩島一朗  日本循環器学会近畿地方会(Web)  124th-  KINKI124,D17 (WEB ONLY)  2017
  • 林旺城; 吉尾拓朗; 野田哲平; 山口眞由子; 横井満; 太田垣宗光; 高橋広季; 松村光一郎; 吉岡慶; 上山敬直; 朴幸男; 高木雅彦; 山本克浩; 塩島一朗  日本循環器学会近畿地方会(Web)  124th-  KINKI124,F33 (WEB ONLY)  2017
  • ST上昇型心筋梗塞患者において糖尿病が心筋血流および心血管死亡率に及ぼす影響(Impact of Diabetes Mellitus on Myocardial Perfusion and Cardiovascular Mortality in Patients with ST-segment Elevation Myocardial Infarction)
    Matsumura Koichiro; Park Haeng; Yoshio Takuro; Hata Yoshihiro; Noda Teppei; Yoshioka Kei; Ueyama Takanao; Sakuma Takao; Iharada Yoshiji; Yamamoto Yoshihiro; Shiojima Ichiro  Circulation Journal  80-  (Suppl.I)  2939  -2939  2016/03
  • 西浦崇; 大谷雄一; 吉尾拓朗; 野田哲平; 佐久間孝雄; 横井満; 太田垣宗光; 松村光一郎; 吉岡慶; 上山敬直; 朴幸男; 居原田善司; 山本克浩; 塩島一朗  日本循環器学会近畿地方会(Web)  122nd-  KINKI122,H22 (WEB ONLY)  2016
  • 岩崎慧; 松村光一郎; 横井満; 太田垣宗光; 吉尾拓朗; 野田哲平; 吉岡慶; 佐久間孝雄; 上山敬直; 朴幸男; 居原田善司; 山本克浩; 塩島一朗  日本循環器学会近畿地方会(Web)  122nd-  KINKI122,H14 (WEB ONLY)  2016
  • CTO遠位側の狭窄のある枝の保護にレトロからのCorsairが有用であった一例(Corsair is Effective to Protect Distal Stenotic Branch of CTO Site via Retrograde Septal Channel Crossing)
    Park Haengnam; Matsumura Koichiro; Sakuma Takao; Yamamoto Yoshihiro  日本心血管インターベンション治療学会抄録集  24回-  1759  -1759  2015/07
  • 田中慧; 吉岡慶; 吉尾拓朗; 秦亮嘉; 松村光一郎; 野田哲平; 上山敬直; 佐久間孝雄; 朴幸男; 居原田善司; 山本克浩; 塩島一朗  日本循環器学会近畿地方会(Web)  119th-  KINKI119,C09 (WEB ONLY)  2015
  • 上嶋貴之; 田中慧; 吉尾拓朗; 松村光一郎; 秦亮嘉; 野田哲平; 吉岡慶; 上山敬直; 佐久間孝雄; 朴幸男; 居原田善司; 山本克浩; 塩島一朗  日本循環器学会近畿地方会(Web)  120th-  KINKI120,G07 (WEB ONLY)  2015
  • 松村光一郎; 上山敬直; 秦亮嘉; 野田哲平; 吉岡慶; 朴幸男; 居原田善司; 山本克浩; 大谷肇; 塩島一朗  日本循環器学会近畿地方会(Web)  117th-  KINKI117,C07 (WEB ONLY)  2014
  • 富田英梨; 朴幸男; 秦亮嘉; 松村光一郎; 野田哲平; 吉岡慶; 上山敬直; 居原田善司; 山本克浩; 大谷肇; 塩島一朗  日本循環器学会近畿地方会(Web)  117th-  KINKI117,G09 (WEB ONLY)  2014
  • 松本宙士; 松村光一郎; 秦亮嘉; 野田哲平; 吉岡慶; 上山敬直; 朴幸男; 居原田善司; 山本克浩; 大谷肇; 塩島一朗  日本循環器学会近畿地方会(Web)  117th-  KINKI117,D06 (WEB ONLY)  2014
  • 吉尾拓朗; 佐久間孝雄; 山本克浩; 居原田善司; 朴幸男; 上山敬直; 吉岡慶; 野田哲平; 松村光一郎; 秦亮嘉; 塩島一朗  日本循環器学会近畿地方会(Web)  118th-  KINKI118,B02 (WEB ONLY)  2014
  • 坂東和典; 吉岡慶; 吉尾拓朗; 松村光一郎; 秦亮嘉; 野田哲平; 佐久間孝雄; 上山敬直; 朴幸男; 居原田善司; 山本克浩; 塩島一朗; 木下竜臣; 桑内慎太郎; 高味良行; 川副浩平  日本循環器学会近畿地方会(Web)  118th-  KINKI118,E07 (WEB ONLY)  2014
  • エベロリムス溶出性ステント留置後の初期および中期成績(Initial and midterm results after everolims eluting stent implantation)
    Funatsu Atsushi; Ejima Emiko; Matsumura Koichiro; Hayashi Fumiyuki; Shibata Kensaku; Mizobuchi Masahiro; Kobayashi Tomoko; Nakamura Shigeru  日本心血管インターベンション治療学会誌  4-  (Suppl.2)  459  -459  2012/06
  • 冠血管攣縮性狭心症患者の予後(Prognosis of Patients with Coronary Vasospastic Angina)
    Kobayashi Tomoko; Ejima Emiko; Matsumura Koichiro; Hayashi Fumiyuki; Shibata Kensaku; Mizobuchi Masahiro; Funatsu Atsushi; Nakamura Shigeru  Circulation Journal  76-  (Suppl.I)  1788  -1788  2012/03
  • 急性深部静脈血栓症を伴う腸骨静脈圧迫症候群に対するステント留置(Stent Implantation for Iliac Compression Syndrome with Acute Deep Venous Thrombosis)
    Funatsu Atsushi; Ejima Emiko; Matsumura Koichiro; Hayashi Fumiyuki; Shibata Kensaku; Mizobuchi Masahiro; Kobayashi Tomoko; Nakamura Shigeru  Circulation Journal  76-  (Suppl.I)  2202  -2202  2012/03
  • 林典行; 江島恵美子; 松村光一郎; 柴田兼作; 溝渕正寛; 舩津篤史; 小林智子; 中村茂  日本循環器学会近畿地方会(Web)  113th-  KINKI113,C02 (WEB ONLY)  2012
  • 江島恵美子; 松村光一郎; 林典行; 柴田兼作; 溝渕正寛; 舩津篤史; 小林智子; 中村茂  日本心臓病学会誌  6-  (Supplement 1)  443  2011/08
  • 松村光一郎; 江島恵美子; 林典行; 柴田兼作; 溝渕正寛; 舩津篤史; 小林智子; 中村茂  日本心臓病学会誌  6-  (Supplement 1)  355  2011/08
  • シロリムス溶出性ステント留置後の長期成績に関する検討(Long-term clinical outcome of the patients after Sirolimus-eluting stent implantation)
    Funatsu Atsushi; Matsumura Koichiro; Ejima Emiko; Yazaki Yoshiyuki; Shibata Kensaku; Mizobuchi Masahiro; Kobayashi Tomoko; Nakamura Shigeru  日本心血管インターベンション治療学会抄録集  20回-  411  -411  2011/06
  • 冠動脈慢性完全閉塞病変に対する逆行性アプローチの有効性(Efficacy of retrograde approach intervention for chronic total occlusion of the coronary arteries)
    Kobayashi Tomoko; Matsumura Koichiro; Ejima Emiko; Yazaki Yoshiyuki; Shibata Kensaku; Mizobuchi Masahiro; Funatsu Atsushi; Nakamura Shigeru  日本心血管インターベンション治療学会抄録集  20回-  461  -461  2011/06
  • 非保護主幹部分岐部への待期的cypherステント留置後の臨床成績(Clinical results after elective Cypher stent implantaion in non-protected LMT bifurcation)
    Kobayashi Tomoko; Matsumura Koichiro; Ejima Emiko; Yazaki Yoshiyuki; Shibata Kensaku; Mizobuchi Masahiro; Funatsu Atsushi; Nakamura Shigeru  日本心血管インターベンション治療学会抄録集  20回-  489  -489  2011/06
  • Sirolimus溶出ステント留置後の長期臨床転帰(Long-term Clinical Outcome after Sirolimus-eluting Stent Implantation)
    Funatsu Atsushi; Matsumura Koichiro; Ejima Emiko; Yazaki Yoshiyuki; Shibata Kensaku; Mizobuchi Masahiro; Kobayashi Tomoko; Enjoji Yoshihisa; Nakamura Shigeru  Circulation Journal  75-  (Suppl.I)  80  -80  2011/03
  • 菊池早苗; 正木浩哉; 秦亮嘉; 辻本大輔; 松村光一郎; 山原英樹; 今田崇裕; 西川三重; 岩坂壽二  日本透析医学会雑誌  42-  (Supplement 1)  683  2009/05
  • 松村光一郎; 佐久間孝雄; 万木孝富; 宮坂陽子; 拝殿未央; 森口暁; 湯浅文雄; 岩坂壽二  Circulation Journal  71-  (Supplement 3)  997  -997  2007/10
  • 松村 光一郎; 佐久間 孝雄; 万木 孝富; 宮坂 陽子; 拝殿 未央; 森口 暁; 湯浅 文雄; 岩坂 壽二  Circulation journal : official journal of the Japanese Circulation Society  71-  (0)  997  -997  2007/10

Awards & Honors

  • 2022/12 2022年度日本抗加齢医学会 研究奨励賞
  • 2022/10 第26回日本心不全学会学術集会 優秀演題賞
  • 2022/07 近畿大学医学会賞
  • 2021/06 JACR AsiaPRevent 2021 Award of Excellence

Research Grants & Projects

  • 日本学術振興会：科学研究費助成事業 基盤研究(C)
    Date (from‐to) : 2023/04 -2028/03 
    Author : 松村 光一郎
  • COVID-19パンデミック下における心血管疾患患者の医療機関受診控えとオンライン診療の普及について
    2022年 先進医薬研究振興財団 循環医学分野一般研究助成：
    Date (from‐to) : 2022/12 -2023/11
  • Novel prognostic marker using skeletal muscle mass and function in elderly acute decompensated heart failure
    Fukuda Foundation for Medical Technology：
    Date (from‐to) : 2020/07 -2021/05 
    Author : 松村 光一郎
  • 末期腎不全患者に対する血管内溶血の病態的意義
    2019年 中谷医工計測技術振興財団 調査研究助成：
    Date (from‐to) : 2019/03 -2021/03 
    Author : 松村 光一郎

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