KINDAI UNIVERSITY


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KUMAMOTO Kazumasa

Profile

FacultyGeneral Education Division
PositionAssociate Professor
Degree
Commentator Guidehttps://www.kindai.ac.jp/meikan/1190-kumamoto-kazumasa.html
URL
Mail
Last Updated :2020/07/08

Education and Career

Education

  •  - 1986 , Nippon Sport Science University, Graduate School, Division of Physical Recreation

Research Activities

Research Areas

  • Life sciences, Physiology
  • Life sciences, Nutrition and health science
  • Life sciences, Sports science

Research Interests

  • Bioengineering, and Nutritional physiology), Environmental Physiology (including Physical Fitness and Sports Medicine, Physical Education

Misc

  • Determination of mazimum fat oxydation rate during walking in middle aged health men and women, The Reserch Bulletin of Health and Sports Sciences, 8, 1, 47, 54,   2009 03
  • Identification of a radical formed in the reaction mixtures of oxidized phosphatidylcholine with ferrous ions using HPLC-ESR and HPLC-ESR-MS, K Kumamoto, T Hirai, S Kishioka, H Iwahashi, FREE RADICAL RESEARCH, 39, 9, 987, 993,   2005 09 , 10.1080/10715760500232073
    Summary:Identification of free radicals was performed for the reaction mixtures of autoxidized 1.2-dilinoleoylphosphatidylcholine (DLPC) with ferrous ions (or DLPC hydroperoxide with ferrous ions) and of DLPC with soybean lipoxygenase using electron spin resonance (ESR), high performance liquid chromatography (HPLC)-ESR and HPLC-ESR-mass spectrometry (MS) combined use of spin trapping technique. ESR measurements of the reaction mixtures showed prominent signals with hyperfine coupling constants (a(N) = 1.58 mT and a(H)beta = 0.26 mT). Outstanding peaks with almost same retention times (autoxidized DLPC, 36.9 min; DLPC hydroperoxicle, 35.0 min; DLPC with soybean lipoxygenase, 37.1 min) were observed on the elution profile of the HPLC-ESR analyses of the reaction mixtures. HPLC-ESR-MS analyses of the reaction mixtures gave two ions at m/z 266 and 179, suggesting that 4-POBN/pentyl radical adduct forms in these reaction mixtures.
  • Identification of 1-ethoxyethyl radicals in the reaction of ferrous ions with serums from rats exposed to diethyl ether., Toxicology Letters, 154(3): 235-239,   2004 , 10.1016/j.toxlet.2004.08.007
  • The formation of the 7-carboxyheptyl radical from 13-hydroperoxy-9,11-octadecadienoic acid catalyzed by hemoglobin and myoglobin under anaerobic conditions, H Iwahashi, K Kumamoto, T Hirai, JOURNAL OF BIOCHEMISTRY, 133, 5, 679, 685,   2003 05 , 10.1093/jb/mvg087
    Summary:Methemoglobin (MetHb), oxyhemoglobin (oxyHb), metmyoglobin (metMb), and oxymyoglobin (oxyMb) catalyze formation of the 7-carboxyheptyl and pentyl radicals from 13-hydroperoxy-9,11-octadecadienoic acid. The relative HPLG-ESR peak height of the pentyl radical to the 7-carboxyheptyl radical was found to depend on the oxygen concentration in the reaction mixture. Under aerobic conditions, the 7-carboxyheptyl radical was predominant for the reaction mixture with ferrous ions (or cytochrome c, metHb, or metMb). On the other hand, under anaerobic conditions, the pentyl radical was predominant for the reaction mixture with ferrous ions (or cytochrome c), but the 7-carboxyheptyl radical was still predominant for the reaction mixture with metHb (or metMb), suggesting that metHb (or metMb) catalyzes the reaction through a mechanism different from that in the case of ferrous ions (or cytochrome c). In order to explain the above results, a mechanism, in which molecular oxygen is not involved, is proposed for the formation of the 7-carboxyheptyl radical in the reaction mixture of 13-HPODE with metHb (or metMb) under anaerobic conditions.
  • The formation of the 7-carboxyheptyl radical from 13-hydroperoxy-9,11-octadecadienoic acid catalyzed by hemoglobin and myoglobin under anaerobic conditions, H Iwahashi, K Kumamoto, T Hirai, JOURNAL OF BIOCHEMISTRY, 133, 5, 679, 685,   2003 05 , 10.1093/jb/mvg087
    Summary:Methemoglobin (MetHb), oxyhemoglobin (oxyHb), metmyoglobin (metMb), and oxymyoglobin (oxyMb) catalyze formation of the 7-carboxyheptyl and pentyl radicals from 13-hydroperoxy-9,11-octadecadienoic acid. The relative HPLG-ESR peak height of the pentyl radical to the 7-carboxyheptyl radical was found to depend on the oxygen concentration in the reaction mixture. Under aerobic conditions, the 7-carboxyheptyl radical was predominant for the reaction mixture with ferrous ions (or cytochrome c, metHb, or metMb). On the other hand, under anaerobic conditions, the pentyl radical was predominant for the reaction mixture with ferrous ions (or cytochrome c), but the 7-carboxyheptyl radical was still predominant for the reaction mixture with metHb (or metMb), suggesting that metHb (or metMb) catalyzes the reaction through a mechanism different from that in the case of ferrous ions (or cytochrome c). In order to explain the above results, a mechanism, in which molecular oxygen is not involved, is proposed for the formation of the 7-carboxyheptyl radical in the reaction mixture of 13-HPODE with metHb (or metMb) under anaerobic conditions.
  • Mechanical Efficiency of Squatting Exercise with Countermovement, The Research Bulletin of the Faculty of General Education, 23, 3,   1992
  • Physical Fitness Testing : Evaluation and Issues, Osaka Research Journal of Physical Education, 28,29,   1991
  • Trends of Physical Fitness in Freshmen of Osaka University of Pharmaceutical Sciences from 1986 to 1989, 14,   1990
  • Net joint forces and moments on ankle, knee, and hip joints during full squat movement,   1986

Research Grants & Projects

  • mechanical efficiency of human movement in sports