KINDAI UNIVERSITY


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KAWASAKI Naohito

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FacultyDepartment of Pharmacy / Graduate School of Medicine / Pharmaceutical Research and Technology Institute
PositionProfessor
Degree
Commentator Guidehttps://www.kindai.ac.jp/meikan/910-kawasaki-naohito.html
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Last Updated :2020/08/10

Education and Career

Academic & Professional Experience

  •   2010 ,  - 現在, Faculty of Pharmacy, Kindai University
  •   2007 ,  - 2010 , Faculty of Pharmacy, Kindai University
  •   2002 ,  - 2007 , Faculty of Pharmacy, Kindai University
  •   1998 ,  - 2002 , Faculty of Pharmacy, Kindai University

Research Activities

Research Areas

  • Life sciences, Pharmaceuticals - health and biochemistry
  • Life sciences, Healthcare management, medical sociology
  • Life sciences, Hygiene and public health (non-laboratory)
  • Life sciences, Hygiene and public health (laboratory)
  • Life sciences, Hygiene and public health (non-laboratory)
  • Life sciences, Hygiene and public health (laboratory)
  • Life sciences, Healthcare management, medical sociology
  • Environmental science/Agricultural science, Environmental policy and society
  • Environmental science/Agricultural science, Environmental impact assessment

Research Interests

  • Anti-ageing, Environmetal hygine, Toxicology, Water Purification, Surface Modification, Air Pollution

Published Papers

  • Evaluation of nickel-aluminium complex hydroxide for adsorption of chromium(VI) ion, Fumihiko Ogata, Takehiro Nakamura, Megumu Toda, Masashi Otani, Naohito Kawasaki, Chemical and Pharmaceutical Bulletin, Chemical and Pharmaceutical Bulletin, 68(1), 70 - 76, 2020 , Refereed
    Summary:© 2020 The Pharmaceutical Society of Japan In this study, nickel-aluminium complex hydroxides at different molar ratios (nickel-aluminium=1:2, 1:1, 2:1, 3:1, and 4:1, referred to as NA12, NA11, NA21, NA31, and NA41) were prepared, and their adsorption capability for chromium(VI) ion was investigated. Firstly, physicochemical characteristics (SEM images, X-ray diffraction (XRD) patterns, specific surface area, amount of hydroxyl groups, and surface pH) of nickel-aluminum complex hydroxide were evaluated. The amount of chromium(VI) ion adsorbed onto NA11 (15.3mg/g) was greater than that adsorbed onto the other adsorbents. This research elucidated that the amount of chromium(VI) ion adsorbed using nickel-aluminium complex hydroxide was related to the adsorbent surface properties (r=0.818-0.875). Subsequently, the adsorbent (NA11) surface before and after adsorption of chromium(VI) ion was evaluated, and chromium energy (577 and 586eV) detected after adsorption onto the NA11 surface. These results revealed that the NA11 surface properties were very important for the removal of chromium(VI) ion from aqueous solution. In addition, the effects of pH, contact time, and temperature on the adsorption of chromium(VI) ion were evaluated. We confirmed a high recovery percentage of chromium(VI) ion when using sodium hydroxide solution at 10-1000mmol/L (approximately greater than 80%) in this experimental condition. Thus, NA11 is a promising adsorbent for the removal of chromium(VI) ion from aqueous solution.
  • PO43- adsorption in a complex solution by nickel-cobalt hydroxide, and its cytotoxicity on bovine aortic endothelial cells, Fumihiko Ogata, Takehiro Nakamura, Masataka Nakajima, Megumu Toda, Masashi Otani, Naohito Kawasaki, Journal of Environmental Chemical Engineering, Journal of Environmental Chemical Engineering, 7(4), Aug. 2019 , Refereed
    Summary:© 2019 Elsevier Ltd. All rights reserved. A nickel-cobalt complex hydroxide was prepared by mixing nickel and cobalt in the ratio of 9:1 (NC91-virgin) and then performing calcination at 280 °C (NC91-280). The adsorption of PO43- by both NC91-virgin and NC91-280 in a complex solution system was evaluated. A higher amount of PO43- was adsorbed by NC91-280 than by NC91-virgin. These results suggest that the adsorption of PO43- is related to the physicochemical properties of the adsorbents. In addition, PO43- was selectively adsorbed by NC91-280 in the complex solution. A pH of approximately 2-3 was optimal for the adsorption of PO43-. The amount of adsorbed PO43- increased with temperature. The adsorption isotherm data were applied to both the Freundlich and Langmuir models. NC91-280 was reused for the adsorption/desorption of PO43- at five times. We could confirm a high recovery percentage of PO43- using a NaOH solution at 1000 mmol/L under the tested experimental conditions. Moreover, we could elucidate the mechanism behind PO43- adsorption in the complex solution. The intensity of P on the surface of NC91-280 increased after adsorption, and peaks of P(2s) and P(2p) were detected by X-ray photoelectron spectroscopy. Finally, we showed that NC91-280 had low a cytotoxic effect on vascular endothelial cells.
  • Combination with l-Menthol Enhances Transdermal Penetration of Indomethacin Solid Nanoparticles., Nagai N, Ogata F, Yamaguchi M, Fukuoka Y, Otake H, Nakazawa Y, Kawasaki N, International journal of molecular sciences, International journal of molecular sciences, 20(15), Jul. 2019 , Refereed
  • Interaction between phosphate ions and Fe-Mg type hydrotalcite for purification of wastewater, Ogata Fumihiko, Nagai Noriaki, Kishida Mao, Nakamura Takehiro, Kawasaki Naohito, JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING, JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING, 7(1), Feb. 2019 , Refereed
  • Adsorption Capability of Fe-HT3.0 for Nitrite and Nitrate Ions in a Binary Solution System., Fumihiko Ogata, Noriaki Nagai, Takehiro Nakamura, Naohito Kawasaki, Chemical & pharmaceutical bulletin, Chemical & pharmaceutical bulletin, 67(10), 1168 - 1170, 2019 , Refereed
    Summary:In this study, the adsorption capability of Fe-HT3.0 for nitrite and nitrate ions in a binary solution system was evaluated. It was found that the amount of nitrite and nitrate ions adsorbed in a single solution (1.19 and 1.27 mmol/g, respectively) was higher than that in a binary solution (0.36 and 0.90 mmol/g, respectively). Equilibrium adsorption was attained within 6-24 h. The adsorption data were fitted to a pseudo-second-order model (correlation coefficient: 0.999), and indicated that the adsorption of both nitrite and nitrate ions is controlled by chemical sorption. Additionally, the binding energies before and after the adsorption of nitrite and nitrate ions in the binary solution system were measured. After adsorption, new nitrogen peaks (approx. 399 and 403 eV) were detected. The results of this study show the potential of Fe-HT3.0 for the removal of nitrite and nitrate ions from aqueous solution systems.
  • Adsorption capability of virgin and calcined wheat bran for molybdenum present in aqueous solution and elucidating the adsorption mechanism by adsorption isotherms, kinetics, and regeneration, Ogata Fumihiko, Nakamura Takehiro, Kawasaki Naohito, JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING, JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING, 6(4), 4459 - 4466, Aug. 2018 , Refereed
  • Involvement of Endocytosis in the Transdermal Penetration Mechanism of Ketoprofen Nanoparticles, Noriaki Nagai, Fumihiko Ogata, Miyu Ishii, Yuya Fukuoka, Hiroko Otake, Yosuke Nakazawa, Naohito Kawasaki, International Journal of Molecular Sciences, International Journal of Molecular Sciences, 19(7), 2138, Jul. 23 2018
    Summary:© 2018 by the authors. Licensee MDPI, Basel, Switzerland. We previously designed a novel transdermal formulation containing ketoprofen solid nanoparticles (KET-NPs formulation), and showed that the skin penetration from the KET-NPs formulation was higher than that of a transdermal formulation containing ketoprofen microparticles (KET-MPs formulation). However, the precise mechanism for the skin penetration from the KET-NPs formulation was not clear. In this study we investigated whether energy-dependent endocytosis relates to the transdermal delivery from a 1.5% KET-NPs formulation. Transdermal formulations were prepared by a bead mill method using additives including methylcellulose and carbopol 934. The mean particle size of the ketoprofen nanoparticles was 98.3 nm. Four inhibitors of endocytosis dissolved in 0.5% DMSO (54 µM nystatin, a caveolae-mediated endocytosis inhibitor; 40 µM dynasore, a clathrin-mediated endocytosis inhibitor; 2 µM rottlerin, a macropinocytosis inhibitor; 10 µM cytochalasin D, a phagocytosis inhibitor) were used in this study. In the transdermal penetration study using a Franz diffusion cell, skin penetration through rat skin treated with cytochalas
  • Evaluation of phosphate ion adsorption from aqueous solution by nickel-aluminum complex hydroxides., Ogata F, Toda M, Otani M, Nakamura T, Kawasaki N, Water science and technology : a journal of the International Association on Water Pollution Research, Water science and technology : a journal of the International Association on Water Pollution Research, 2017(3), 913 - 921, Jul. 2018 , Refereed
  • Involvement of Endocytosis in the Transdermal Penetration Mechanism of Ketoprofen Nanoparticles., Nagai N, Ogata F, Ishii M, Fukuoka Y, Otake H, Nakazawa Y, Kawasaki N, International journal of molecular sciences, International journal of molecular sciences, 19(7), Jul. 2018 , Refereed
  • Simultaneous Removal of Dye and Chemical Oxygen Demand from Aqueous Solution by Combination Treatment with Ozone and Carbonaceous Material Produced from Waste Biomass, Ogata Fumihiko, Nagahashi Eri, Kobayashi Yuhei, Nakamura Takehiro, Kawasaki Naohito, E-JOURNAL OF SURFACE SCIENCE AND NANOTECHNOLOGY, E-JOURNAL OF SURFACE SCIENCE AND NANOTECHNOLOGY, 16, 229 - 235, Jun. 07 2018 , Refereed
  • Improvement of the Homogeneous Fenton Reaction for Degradation of Methylene Blue and Acid Orange II., Ogata F, Nakamura T, Kawasaki N, Chemical & pharmaceutical bulletin, Chemical & pharmaceutical bulletin, 66(5), 585 - 588, May 2018 , Refereed
  • Characteristics of a novel adsorbent Fe-Mg-type hydrotalcite and its adsorption capability of As(III) and Cr(VI) from aqueous solution, Ogata Fumihiko, Ueta Erimi, Kawasaki Naohito, JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY, JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY, 59, 56 - 63, Mar. 25 2018 , Refereed
  • 水溶性薬物の角膜透過性向上を目指して:チモロールマレイン酸・マグネシウムヒドロキシドナノ粒子配合剤の開発, NAKAZAWA Yosuke, 日本眼科学会雑誌, 日本眼科学会雑誌, 122(1), 61 - 62, Jan. 20 2018
  • Effects of Water Addition to Prevent Deterioration of Soybean Oil by Calcium Silicate Adsorbent., Ogata F, Obayashi M, Nagahashi E, Nakamura T, Kawasaki N, Journal of oleo science, Journal of oleo science, 67(1), 95 - 103, Jan. 2018 , Refereed
  • Design of a transdermal formulation containing raloxifene nanoparticles for osteoporosis treatment., Nagai N, Ogata F, Otake H, Nakazawa Y, Kawasaki N, International journal of nanomedicine, International journal of nanomedicine, 13, 5215 - 5229, 2018 , Refereed
  • Adsorption of tungsten ion with a novel Fe-Mg type hydrotalcite prepared at different Mg2+/Fe3+ ratios, Ogata Fumihiko, Nakamura Takehiro, Ueta Erimi, Nagahashi Eri, Kobayashi Yuhei, Kawasaki Naohito, JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING, JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING, 5(4), 3083 - 3090, Aug. 2017 , Refereed
  • Adsorption Capability of Ionic Dyes onto Pristine and Calcined Activated Clay, Ogata Fumihiko, Ueta Erimi, Kawasaki Naohito, E-JOURNAL OF SURFACE SCIENCE AND NANOTECHNOLOGY, E-JOURNAL OF SURFACE SCIENCE AND NANOTECHNOLOGY, 14, 209 - 215, Oct. 08 2016 , Refereed
  • Elucidation of Hair Loss Factors and Hair Growth Promoting Effects of Broccoli Sprouts Extract, TSUZUKI HIROAKI, WATANABE NAOKO, OKAMURA KATSUMASA, YAMADA HIDEKAZU, YAMADA HIDEKAZU, OGATA FUMIHIKO, KAWASAKI NAOHITO, KAWASAKI NAOHITO, Fragr J, Fragr J, 44(1), 14 - 20, Jan. 15 2016
  • Adsorption of nitrate and nitrite ions onto carbonaceous material produced from soybean in a binary solution system, Ogata Fumihiko, Imai Daisuke, Kawasaki Naohito, JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING, JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING, 3(1), 155 - 161, Mar. 2015 , Refereed
  • Corneal Wound Healing Rate Delay in Ovariectomized Rats Receiving Low-calcium Diet, NAGAI NORIAKI, OGATA FUMIHIKO, FUNAKAMI YOSHINORI, ITO YOSHIMASA, KAWASAKI NAOHITO, あたらしい眼科, あたらしい眼科, 30(11), 1623 - 1627, Nov. 30 2013
    Summary:加齢に伴う全身性機能の変化が視覚(眼領域)へ及ぼす影響を明確にすることは、超高齢化社会を迎えるわが国において非常に重要である。本研究では、閉経後のカルシウム不足と角膜上皮傷害の自己修復機能の関係を明らかとすべく、卵巣摘出ラットへの低カルシウム食投与時における角膜上皮傷害治癒速度について検討を行った。1ヵ月間の低カルシウム食(低カルシウム飼料および精製水)投与は体重、飼料摂取量および飲水量に影響を与えなかったが、血中および骨中カルシウム量の低下がみられた。また、これらカルシウム欠乏ラットの角膜上皮を剥離し、一次速度式にて角膜傷害治癒速度定数を算出したところ、正常ラットと比較し、角膜傷害治癒速度定数が有意に低値を示した。以上、本研究では卵巣摘出モデルを用いたin vivo実験において、低カルシウム食摂取時には角膜傷害治癒速度が低下することを明らかとした。(著者抄録)
  • Phosphate-ion-adsorption capability of granulated boehmite fabricated using organic binder (polyethylene terephthalate)., Ogata F, Ueda A, Kawasaki N, Chemical & pharmaceutical bulletin, Chemical & pharmaceutical bulletin, 61(10), 1030 - 1036, Oct. 2013 , Refereed
  • Study on Relationship between Physical Fitness and Lifestyle of University Students in Japan, TOMINAGA HISATO, SAGAWA KAZUNORI, OGATA FUMIHIKO, KAWASAKI NAOHITO, KAWASAKI NAOHITO, 保健医療学雑誌(Web), 保健医療学雑誌(Web), 4(1), 9-16 (WEB ONLY) - 16, Apr. 01 2013
    Summary:2011年に生涯スポーツ講義を受講した男子学生2198名、女子学生794名(平均18.6歳)を対象に、体力測定と生活習慣・心身の健康状態に関するアンケート調査を行い、その関連性について検討した。その結果、学生の体力項目の測定値は、男女とも背筋力を除きほぼ全国水準であった。男子学生では朝食摂取していない割合が、女子学生に比べ有意に高かった。また、各生活習慣に関する指標について男女別で比較すると、男子学生は女子学生に比べ身体的状態が高く、精神的状態はPositive思考であった。食習慣、睡眠習慣、運動習慣の満足度については、男子学生で有意に高値を示し、生活習慣および心身の健康状態の自己評価は男子学生の方が高かった。体力との関連では、男子学生は身体的状態、精神的状態、運動習慣との間に、女子学生は身体的状態との間に有意な相関関係が示された。
  • Practical safety of using essential medicines and their market products in Thailand, Int. J. Risk Safety Med, Int. J. Risk Safety Med, 17, 251 - 256, Jun. 2010
  • Adsorption of phosphate by cerium hydroxide, e-J. Surf. Sci. Nanotech, e-J. Surf. Sci. Nanotech, 8, 258 - 260, May 2010
  • Factors associated with the market availability of systemic anti-infective products in Thailand (no.743), J. Public Health, J. Public Health, 17, 251 - 256, Mar. 2009
  • Relationship between anion adsorption and physicochemical properties of aluminum oxide, J. Health Sci., J. Health Sci., 53(3), 324 - 329, Mar. 2008
  • Relationship between strength and life style on pharmaceutical university students in Japan and Thailand, Jpn. B. Health Fit. Nutr., Jpn. B. Health Fit. Nutr., 13(1), 44 - 51, Jan. 2008
  • Relationship between mood states and heart rate variability coefficient & event related potential P300 by long-term auditory stimuli with strong 1/f fluctuation in healthy young women, Jpn. B. Health Fit. Nutr., Jpn. B. Health Fit. Nutr., 13(1), 10 - 18, Jan. 2008
  • Effect of long-term auditory stimuli with strang 1/f fluctuation on food intake and taste in healthy young women, Jpn. B. Health Fit. Nutr., Jpn. B. Health Fit. Nutr., 13(1), 19 - 31, Jan. 2008
  • タイおよび日本における大学生の身体的・精神的状態と睡眠習慣との関連性, KAWASAKI NAOHITO, TANEI SHIGEHARU, BURAPADAJA SIRIPORN, LOETKHAM CHAOWALIT, OGATA FUMIHIKO, TANADA SEIKI, 日本生理人類学会誌, 日本生理人類学会誌, 12, 66 - 67, Jun. 15 2007
  • Relationship between states of physical or mental and sleeping habits among university students in Thailand and Japan, Jpn. B. Haelth Fit. Nutr., Jpn. B. Haelth Fit. Nutr., 12(1), 20 - 27, Jan. 2007
  • Survey on cellular phone usage on students in Thailand., Kawasaki N, Tanei S, Ogata F, Burapadaja S, Loetkham C, Nakamura T, Tanada S, Journal of physiological anthropology, Journal of physiological anthropology, 25(6), 377 - 382, Nov. 2006 , Refereed
  • Survey on meal habit, hours of sleep and exercise habit of university students in Japan and Thailand, Jpn. B. Health Fit. Nutr., Jpn. B. Health Fit. Nutr., 11, 15 - 22, Nov. 2006
  • Survey on body stature and body habitus among university students in Japan and Thailand, Jpn. B. Health Fit. Nutr., Jpn. B. Health Fit. Nutr., 11, 3 - 14, Nov. 2006
  • Removal of lead and iron ions by vegetable biomass in drinking water, J. Oleo Sci., J. Oleo Sci., 55(8), 423 - 427, Aug. 2006
  • Survey on cellular phone usage on students in Thailand, J. Physiological Anthropology, J. Physiological Anthropology, 25(6), 377 - 382, Jun. 2006
  • Structural transformation of gibbsite by calcination, e-J. Surf. Sci. Nanotech., e-J. Surf. Sci. Nanotech., 4, 267 - 269, Mar. 2006
  • Water treatment technology of mineral release type using vegetable biomass, J. Water Environ. Technol., J. Water Environ. Technol., 4(1), 73 - 82, Jan. 2006
  • Relationship between surface polarity and moisture control onto carbonaceous materials produced from bean curd lees, J. Oleo Sci., J. Oleo Sci., 55(1), 23 - 29, Jan. 2006
  • Deodorization of ammonia by coffee grounds, J. Oleo Sci., J. Oleo Sci., 55(1), 31 - 35, Jan. 2006
  • Paraquat and diquat removal by chitosan derivatives, Bull. Pharm. Res. Technol. Inst., Bull. Pharm. Res. Technol. Inst., 13, 35 - 41, Mar. 2005
  • Adsorption/desorption characteistics of phosphate ion onto calcined boehmite surface, e-J. Surf.Sci.Nanotech., e-J. Surf.Sci.Nanotech., 3, 63 - 69, Jan. 2005
  • Effect of particle size on the adsorption of theophylline onto activated charcoal, in vitro study, Bull. Pharm. Res. Tschnol. Inst., Bull. Pharm. Res. Tschnol. Inst., 12, 91 - 98, Mar. 2004
  • Performance of poly-γ-glutamic acid–calcium hydroxide treatment for phosphate removal and applicability of the resulting flocculant as a phosphate-based fertilizer, Fumihiko Ogata, Yuuna Kagiyama, Chalermpong Saenjum, Takehiro Nakamura, Naohito Kawasaki, Bioresource Technology Reports, Bioresource Technology Reports, 11, Sep. 2020 , Refereed
    Summary:© 2020 Elsevier Ltd Herein, we focused on poly-γ-glutamic acid (PG) as a bioresource material for phosphate removal and assessed the efficiency of a combined PG and calcium hydroxide (CH) treatment via elemental distribution and X-ray diffraction analysis. Additionally, this study briefly assessed the applicability of the flocculants obtained from the phosphate removal process as phosphate-based fertilizers. The results showed that phosphate removal capacity was higher when treated with the PG–CH mixture than that with pure PG or CH. Additionally, the phosphate removal treatment with the PG–CH mixture had the advantage of straightforward separation of the supernatant from the flocculant. Moreover, the mechanism of phosphate removal by the PG + CH treatment was evaluated on the basis of elemental distribution and X-ray diffraction analysis. Finally, the flocculants obtained from the PG + CH treatment had 20.5% citric acid-soluble content, indicating their potential as phosphate-based fertilizers.
  • Zeolite produced from fly ash by thermal treatment in alkaline solution and its capability to adsorb Cs(I) and Sr(II) in aqueous solution, Fumihiko Ogata, Yuhei Kobayashi, Yugo Uematsu, Takehiro Nakamura, Naohito Kawasaki, Yakugaku Zasshi, Yakugaku Zasshi, 140(5), 729 - 737, May 01 2020 , Refereed
    Summary:© 2020 The Pharmaceutical Society of Japan In this study, we evaluated the efficiency of fly ash (FA) recycling technology, produced from a coal-fired power plant, with the capability to adsorb cesium ion[Cs(I)] and strontium ion [Sr(II)] from aqueous phase. Zeolite was produced from FA by hydrothermal treatment in an alkaline solution. Zeolite 12, 24, and 48 have a Garronite structure. Moreover, the specific surface area of Zeolite was greater than that of FA. Zeolite 12 demonstrated the adsorption capability of Cs(I) and Sr(II) from aqueous phase. Adsorption isotherms data fitted both the Langmuir equation (correlation coeffiient: >0.895) and the Freundlich equation (correlation coefficient: >0.881). In addition, the kinetic data fitted the pseudo-second-order model when compared to the pseudo-first-order model. Cs(I) and Sr(II) were selectively adsorbed by Zeolite 12 in complex solution system. Our findings indicate that Zeolite can be produced from FA by hydrothermal treatment in an alkaline solution and shows the capability to adsorb Cs(I) and Sr(II) from aqueous phase. Therefore, Zeolite can be useful adsorbent for purification in water environments.
  • Removing Sr(II) and Cs(I) from the aqueous phase using basil seed and elucidating the adsorption mechanism, Yugo Uematsu, Fumihiko Ogata, Chalermpong Saenjum, Takehiro Nakamura, Naohito Kawasaki, Sustainability (Switzerland), Sustainability (Switzerland), 12(7), Apr. 2020 , Refereed
    Summary:© 2020 by the authors. To confirm the capability and mechanisms of Sr(II) and Cs(I) adsorption from the aqueous phase using basil seed (BS), virgin BS, calcined BS (BS500 and BS1000), and enzymatically treated BS, namely Mannanase BGM (M-BS), Pectinase G (P-BS), Hemicellulase (H-BS), and Cellulase A (C-BS) was evaluated. The adsorption capabilities of Sr(II) and Cs(I) of various BS adsorbents were also evaluated. The quantity of Sr(II) and Cs(I) adsorbed onto BS was greater than that of BS500 or BS1000, suggesting that the physicochemical characteristics of the BS surface affected Sr(II) and Cs(I) removal from the aqueous phase. Furthermore, the quantity of Sr(II) and Cs(I) adsorbed onto virgin BS was greater than that of enzymatically treated BS, indicating that glucomannan or (1,4)-xylan in the cellulosic hydrocolloid of the BS strongly affected the adsorption capability of Cs(I) or Sr(II) (except for M-BS in Sr(II) adsorption). Our obtained results indicate that, as an adsorbent, BS was capable of removing Sr(II) and Cs(I) from the aqueous solution.
  • Adsorption of phosphate ions on novel Mg/Fe/Al hydroxides (MFA) prepared at different Mg2+/Fe3+/Al3+ ratios, Takehiro Nakamura, Riku Nagafuji, Fumihiko Ogata, Naohito Kawasaki, Chemical and Pharmaceutical Bulletin, Chemical and Pharmaceutical Bulletin, 68(4), 339 - 344, Apr. 2020 , Refereed
    Summary:© 2020 The Pharmaceutical Society of Japan In this study, we prepared novel Mg/Fe/Al hydroxides (MFA series: denoted by MFA1, MFA2, MF, and MA) and investigated their properties using scanning electron microscopy, X-ray diffraction, the specific surface area, and amount of hydroxyl groups. Additionally, the phosphate adsorption capabilities of the MFA series or Fe–Mg type hydrotalcites (FHT3.0 and FHT5.0) were evaluated by examining the effects of the solution pH and contact time, and analyzing the adsorption isotherm and desorption characteristics. In MFA1, a strong correlation exists between the amount of adsorbed phosphate ions and surface hydroxyl groups, with a correlation coefficient of 0.95. The adsorption kinetics data fitted using the pseudo-second-order model performs better than the pseudo-first-order model. The adsorption isotherm data were also fitted using both the Freundlich and Langmuir models. Finally, the phosphate ions adsorbed on the MFA1 surfaces were desorbed using sodium hydroxide solution. These results indicate that MFA1 offers great potential for phosphate ion adsorption from aqueous solutions and functions as a renewable adsorbent.
  • Oral administration system based on meloxicam nanocrystals: Decreased dose due to high bioavailability attenuates risk of gastrointestinal side effects, Noriaki Nagai, Fumihiko Ogata, Hiroko Otake, Naohito Kawasaki, Pharmaceutics, Pharmaceutics, 12(4), Apr. 2020 , Refereed
    Summary:© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Meloxicam (MLX) is widely applied as a therapy for rheumatoid arthritis (RA); however, it takes far too long to reach its peak plasma concentration for a quick onset effect, and gastrointestinal toxicity has been observed in RA patients taking it. To solve these problems, we designed MLX solid nanoparticles (MLX-NPs) by the bead mill method and used them to prepare new oral formulations. The particle size of the MLX-NPs was approximately 20-180 nm, and they remained in the nano-size range for 1 month. The tmax of MLX-NPs was shorter than that of traditional MLX dispersions (MLX-TDs), and the intestinal penetration of MLX-NPs was significantly higher in comparison with MLX-TDs (P < 0.05). Caveolae-dependent endocytosis (CavME), clathrin-dependent endocytosis (CME), and micropinocytosis (MP) were found to be related to the high intestinal penetration of MLX-NPs. The area under the plasma MLX concentration-time curve (AUC) for MLX-NPs was 5-fold higher than that for MLX-TDs (P < 0.05), and the AUC in rats administered 0.05 mg/kg MLX-NPs were similar to rats administered the therapeutic dose of 0.2 mg/kg MLX-TDs. In addition, the anti-inflammatory effect of the MLX-NPs was also significantly higher than that of MLX-TDs at the corresponding dose (P < 0.05), and the therapeutic effect of 0.2 mg/kg MLX-TDs and 0.05 mg/kg MLX-NPs in adjuvant-induced arthritis (AA) rats showed no difference. Furthermore, the gastrointestinal lesions in AA rats treated repetitively with 0.05 mg/kg MLX-NPs were fewer than in rats receiving 0.2 mg/kg MLX-TDs (P < 0.05). In conclusion, we demonstrate that MLX solid nanoparticles allow a quick onset of therapeutic effect and that three endocytosis pathways, CavME, CME, and MP, are related to the high absorption of solid nanoparticles. In addition, we found that MLX solid nanoparticles make it possible to reduce the amount of orally administered drugs, and treatment with low doses of MLX-NPs allows RA therapy without intestinal ulcerogenic responses to MLX. These findings are useful for designing therapies for RA patients.
  • Potential of virgin and calcined wheat bran biomass for the removal of chromium(VI) ion from a synthetic aqueous solution, Fumihiko Ogata, Noriaki Nagai, Ryo Itami, Takehiro Nakamura, Naohito Kawasaki, JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING, JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING, 8(2), Apr. 2020 , Refereed
    Summary:Virgin wheat bran (WB) and calcined wheat bran were prepared at 500 or 1000 degrees C (WB500 or WB1000, respectively), and their physicochemical properties (such as morphological, thermal, specific surface area, point of zero charge pH, and surface functional groups) were investigated to assess their chromium(VI) ion adsorption capability. The amount of chromium(VI) ion adsorbed was in the order WB < WB500 < WB1000. These results showed that the chromium(VI) ion adsorption was related to the WB surface characteristics. Additionally, the amount of chromium (Cr) and oxygen (O) on the WB1000 surface increased after adsorption, which indicated chromium(VI) ions were adsorbed onto the WB1000 surface. Adsorption isotherm and adsorption kinetic data fit the Freundlich (0.879-0.991) and pseudo-second-order models (0.979-0.997), respectively. The optimal pH condition for the removal of chromium(VI) ion from aqueous solution was approximately 2. Finally, WB1000 could be useful for repetition of chromium(VI) ion adsorption/desorption using sodium hydroxide at 1000 mmol/L (at least five times). It was shown that WB1000 has the potential for adsorption and recovery of chromium(VI) ion from aqueous solution using sodium hydroxide.
  • Removing Sr(II) and Cs(I) from the Aqueous Phase Using Basil Seed and Elucidating the Adsorption Mechanism, Yugo Uematsu, Fumihiko Ogata, Chalermpong Saenjum, Takehiro Nakamura, Naohito Kawasaki, SUSTAINABILITY, SUSTAINABILITY, 12(7), Apr. 2020 , Refereed
    Summary:To confirm the capability and mechanisms of Sr(II) and Cs(I) adsorption from the aqueous phase using basil seed (BS), virgin BS, calcined BS (BS500 and BS1000), and enzymatically treated BS, namely Mannanase BGM (M-BS), Pectinase G (P-BS), Hemicellulase (H-BS), and Cellulase A (C-BS) was evaluated. The adsorption capabilities of Sr(II) and Cs(I) of various BS adsorbents were also evaluated. The quantity of Sr(II) and Cs(I) adsorbed onto BS was greater than that of BS500 or BS1000, suggesting that the physicochemical characteristics of the BS surface affected Sr(II) and Cs(I) removal from the aqueous phase. Furthermore, the quantity of Sr(II) and Cs(I) adsorbed onto virgin BS was greater than that of enzymatically treated BS, indicating that glucomannan or (1,4)-xylan in the cellulosic hydrocolloid of the BS strongly affected the adsorption capability of Cs(I) or Sr(II) (except for M-BS in Sr(II) adsorption). Our obtained results indicate that, as an adsorbent, BS was capable of removing Sr(II) and Cs(I) from the aqueous solution.
  • Oral Administration System Based on Meloxicam Nanocrystals: Decreased Dose Due to High Bioavailability Attenuates Risk of Gastrointestinal Side Effects., Noriaki Nagai, Fumihiko Ogata, Hiroko Otake, Naohito Kawasaki, Pharmaceutics, Pharmaceutics, 12(4), Apr. 01 2020 , Refereed
    Summary:Meloxicam (MLX) is widely applied as a therapy for rheumatoid arthritis (RA); however, it takes far too long to reach its peak plasma concentration for a quick onset effect, and gastrointestinal toxicity has been observed in RA patients taking it. To solve these problems, we designed MLX solid nanoparticles (MLX-NPs) by the bead mill method and used them to prepare new oral formulations. The particle size of the MLX-NPs was approximately 20-180 nm, and they remained in the nano-size range for 1 month. The tmax of MLX-NPs was shorter than that of traditional MLX dispersions (MLX-TDs), and the intestinal penetration of MLX-NPs was significantly higher in comparison with MLX-TDs (P < 0.05). Caveolae-dependent endocytosis (CavME), clathrin-dependent endocytosis (CME), and micropinocytosis (MP) were found to be related to the high intestinal penetration of MLX-NPs. The area under the plasma MLX concentration-time curve (AUC) for MLX-NPs was 5-fold higher than that for MLX-TDs (P < 0.05), and the AUC in rats administered 0.05 mg/kg MLX-NPs were similar to rats administered the therapeutic dose of 0.2 mg/kg MLX-TDs. In addition, the anti-inflammatory effect of the MLX-NPs was also significantly higher than that of MLX-TDs at the corresponding dose (P < 0.05), and the therapeutic effect of 0.2 mg/kg MLX-TDs and 0.05 mg/kg MLX-NPs in adjuvant-induced arthritis (AA) rats showed no difference. Furthermore, the gastrointestinal lesions in AA rats treated repetitively with 0.05 mg/kg MLX-NPs were fewer than in rats receiving 0.2 mg/kg MLX-TDs (P < 0.05). In conclusion, we demonstrate that MLX solid nanoparticles allow a quick onset of therapeutic effect and that three endocytosis pathways, CavME, CME, and MP, are related to the high absorption of solid nanoparticles. In addition, we found that MLX solid nanoparticles make it possible to reduce the amount of orally administered drugs, and treatment with low doses of MLX-NPs allows RA therapy without intestinal ulcerogenic responses to MLX. These findings are useful for designing therapies for RA patients.
  • Characterization and Phosphate Adsorption Capability of Novel Nickel-Aluminum Zirconium Complex Hydroxide, Fumihiko Ogata, Shouko Iijima, Megumu Toda, Masashi Otani, Takehiro Nakamura, Naohito Kawasaki, CHEMICAL & PHARMACEUTICAL BULLETIN, CHEMICAL & PHARMACEUTICAL BULLETIN, 68(3), 292 - 297, Mar. 2020 , Refereed
    Summary:In this study, the adsorption capability of phosphate ion using a novel tri-metals complex hydroxide was evaluated for preventing the eutrophication in water environment. A nickel aluminum zirconium complex hydroxide (NAZ) was synthesized using each inorganic sulfate mixing ratio of 0.9 :1.0 :0.1 and was calcined at different temperatures. The characteristics of the NAZ were analyzed by scanning electron microscopy images, X-ray diffraction analysis, elemental distribution, and binding energy. Moreover, the amount adsorbed of phosphate ion onto uncalcined and calcined NAZ was measured. That of phosphate ions onto the uncalcined was the largest of all. These results suggested that the adsorption of phosphate ions tends to depend on the physicochemical properties (e.g., amount of hydroxyl groups, pore volumes, and pH) of the adsorbents. Moreover, the adsorption mechanism of phosphate ions was evaluated on the basis of binding energy and elemental analysis. After adsorption, the binding energy of phosphorus P (2s and 2p) peaked and the sulfur peak intensity S(2s) reduced. This result indicated that the adsorption mechanism of phosphate would be exchanged with sulfate ions.
  • Novel Sustained-Release Drug Delivery System for Dry Eye Therapy by Rebamipide Nanoparticles., Noriaki Nagai, Miyu Ishii, Ryotaro Seiriki, Fumihiko Ogata, Hiroko Otake, Yosuke Nakazawa, Norio Okamoto, Kazutaka Kanai, Naohito Kawasaki, Pharmaceutics, Pharmaceutics, 12(2), Feb. 14 2020 , Refereed
    Summary:The commercially available rebamipide ophthalmic suspension (CA-REB) was approved for clinical use in patients with dry eye; however, the residence time on the ocular surface for the traditional formulations is short, since the drug is removed from the ocular surface through the nasolacrimal duct. In this study, we designed a novel sustained-release drug delivery system (DDS) for dry eye therapy by rebamipide nanoparticles. The rebamipide solid nanoparticle-based ophthalmic formulation (REB-NPs) was prepared by a bead mill using additives (2-hydroxypropyl-β-cyclodextrin and methylcellulose) and a gel base (carbopol). The rebamipide particles formed are ellipsoid, with a particle size in the range of 40-200 nm. The rebamipide in the REB-NPs applied to eyelids was delivered into the lacrimal fluid through the meibomian glands, and sustained drug release was observed in comparison with CA-REB. Moreover, the REB-NPs increased the mucin levels in the lacrimal fluid and healed tear film breakup levels in an N-acetylcysteine-treated rabbit model. The information about this novel DDS route and creation of a nano-formulation can be used to design further studies aimed at therapy for dry eye.
  • Removal of Sr(II) ions from aqueous solution by human hair treated with EDTA, Fumihiko Ogata, Noriaki Nagai, Akane Soeda, Kaito Yamashiro, Takehiro Nakamura, Chalermpong Saenjum, Naohito Kawasaki, Bioresource Technology Reports, Bioresource Technology Reports, 9, Feb. 2020 , Refereed
    Summary:© 2020 Elsevier Ltd Disposed human hair was treated with different concentrations of ethylenediamine-N,N,N′,N′-tetraacetic acid (EDTA) (10%, 25%, and 50% denoted as ED10, ED25, and ED50, respectively), and its Sr(II) adsorption capacity from the aqueous phase was evaluated. The amount of Sr(II) adsorbed onto ED25 was 17 mg/g. The amount of Sr(II) adsorbed using ED25 depended on the solution pH, and the optimal pH condition was approximately 4 in our experiment. Because the point of zero charge of human hair is approximately 3.67 to 3.70, electrostatic interaction between Sr(II) and human hair easily occurred. Finally, the Sr(II) adsorbed onto ED25 was easily desorbed using a sodium hydroxide solution at a pH of 3 (desorption percentage of 95.4%). EDTA treatment of human hair was useful for producing a novelty adsorbent to adsorb Sr(II) from aqueous solution. These results can be applied to the solution of problems regarding the water environment and waste materials.
  • Characterization and Phosphate Adsorption Capability of Novel Nickel-Aluminum-Zirconium Complex Hydroxide., Fumihiko Ogata, Shouko Iijima, Megumu Toda, Masashi Otani, Takehiro Nakamura, Naohito Kawasaki, Chemical & pharmaceutical bulletin, Chemical & pharmaceutical bulletin, 68(3), 292 - 297, 2020 , Refereed
    Summary:In this study, the adsorption capability of phosphate ion using a novel tri-metals complex hydroxide was evaluated for preventing the eutrophication in water environment. A nickel-aluminum-zirconium complex hydroxide (NAZ) was synthesized using each inorganic sulfate mixing ratio of 0.9 : 1.0 : 0.1 and was calcined at different temperatures. The characteristics of the NAZ were analyzed by scanning electron microscopy images, X-ray diffraction analysis, elemental distribution, and binding energy. Moreover, the amount adsorbed of phosphate ion onto uncalcined and calcined NAZ was measured. That of phosphate ions onto the uncalcined was the largest of all. These results suggested that the adsorption of phosphate ions tends to depend on the physicochemical properties (e.g., amount of hydroxyl groups, pore volumes, and pH) of the adsorbents. Moreover, the adsorption mechanism of phosphate ions was evaluated on the basis of binding energy and elemental analysis. After adsorption, the binding energy of phosphorus P (2s and 2p) peaked and the sulfur peak intensity S(2s) reduced. This result indicated that the adsorption mechanism of phosphate would be exchanged with sulfate ions.
  • Adsorption of Phosphate Ions on Novel Mg/Fe/Al Hydroxides (MFA) Prepared at Different Mg2+/Fe3+/Al3+ Ratios., Takehiro Nakamura, Riku Nagafuji, Fumihiko Ogata, Naohito Kawasaki, Chemical & pharmaceutical bulletin, Chemical & pharmaceutical bulletin, 68(4), 339 - 344, 2020 , Refereed
    Summary:In this study, we prepared novel Mg/Fe/Al hydroxides (MFA series: denoted by MFA1, MFA2, MF, and MA) and investigated their properties using scanning electron microscopy, X-ray diffraction, the specific surface area, and amount of hydroxyl groups. Additionally, the phosphate adsorption capabilities of the MFA series or Fe-Mg type hydrotalcites (FHT3.0 and FHT5.0) were evaluated by examining the effects of the solution pH and contact time, and analyzing the adsorption isotherm and desorption characteristics. In MFA1, a strong correlation exists between the amount of adsorbed phosphate ions and surface hydroxyl groups, with a correlation coefficient of 0.95. The adsorption kinetics data fitted using the pseudo-second-order model performs better than the pseudo-first-order model. The adsorption isotherm data were also fitted using both the Freundlich and Langmuir models. Finally, the phosphate ions adsorbed on the MFA1 surfaces were desorbed using sodium hydroxide solution. These results indicate that MFA1 offers great potential for phosphate ion adsorption from aqueous solutions and functions as a renewable adsorbent.
  • [Zeolite Produced from Fly Ash by Thermal Treatment in Alkaline Solution and Its Capability to Adsorb Cs(I) and Sr(II) in Aqueous Solution]., Fumihiko Ogata, Yuhei Kobayashi, Yugo Uematsu, Takehiro Nakamura, Naohito Kawasaki, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 140(5), 729 - 737, 2020 , Refereed
    Summary:In this study, we evaluated the efficiency of fly ash (FA) recycling technology, produced from a coal-fired power plant, with the capability to adsorb cesium ion[Cs(I)] and strontium ion [Sr(II)] from aqueous phase. Zeolite was produced from FA by hydrothermal treatment in an alkaline solution. Zeolite 12, 24, and 48 have a Garronite structure. Moreover, the specific surface area of Zeolite was greater than that of FA. Zeolite 12 demonstrated the adsorption capability of Cs(I) and Sr(II) from aqueous phase. Adsorption isotherms data fitted both the Langmuir equation (correlation coefficient: >0.895) and the Freundlich equation (correlation coefficient: >0.881). In addition, the kinetic data fitted the pseudo-second-order model when compared to the pseudo-first-order model. Cs(I) and Sr(II) were selectively adsorbed by Zeolite 12 in complex solution system. Our findings indicate that Zeolite can be produced from FA by hydrothermal treatment in an alkaline solution and shows the capability to adsorb Cs(I) and Sr(II) from aqueous phase. Therefore, Zeolite can be useful adsorbent for purification in water environments.
  • Determining of the Water Quality of the Ping River at Different Seasons in Northern Thailand., Fumihiko Ogata, Chalermpong Saenjum, Eri Nagahashi, Yuhei Kobayashi, Takehiro Nakamura, Naohito Kawasaki, Chemical & pharmaceutical bulletin, Chemical & pharmaceutical bulletin, 68(6), 546 - 551, 2020 , Refereed
    Summary:The water quality in a river (water environment) is very important for human health and aquatic organisms. In 2015, the highly regarded Water Resources Management Strategy of Thailand was announced by The Ministry of Industry in Thailand. In this study, the water quality of the Ping river in Northern Thailand, including Chiang Mai and Lamphun provinces, was focused on and measured for three different seasons (summer, rainy, and winter seasons). Anions (F-, Cl-, NO2-, NO3-, and SO42-) and cations (Na+, Mg2+, Si4+, S6+, K+, and Ca2+) were qualified by an ion chromatograph and an inductively coupled plasma optical emission spectrometry, respectively. The concentration of anions and cations (except for Mg2+ and Ca2+) in the Ping river at upstream (countryside) locations were lower than that at downstream (closer main city) locations, which indicated that the fertilizers, industrial or household wastewaters had been flowing into the Ping river at downstream locations. Additionally, the concentration of anions and cations in the rainy season was higher than other seasons. The present results provide the water quality of the Ping river which was not yet reported officially by the Thailand government.
  • Interaction between phosphate ions and Fe-Mg type hydrotalcite for purification of wastewater, Fumihiko Ogata, Noriaki Nagai, Mao Kishida, Takehiro Nakamura, Naohito Kawasaki, JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING, JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING, 7(1), Feb. 2019 , Refereed
    Summary:In this study, Fe-Mg type hydrotalcite at different molar ratios (Mg/Fe=3.0 and 5.0, Fe-HT3.0 and Fe-HT5.0) was prepared, and its physicochemical properties were investigated. The adsorption isotherms were measured, and the effects of contact time, temperature, and pH on the adsorption of phosphate ions, and the ad-desorption capability were evaluated. Elemental analysis and binding energy values of the Fe-HT adsorbent surface before and after adsorption of phosphate ions indicated that the adsorption mechanism of phosphate ions was related to the physicochemical properties of adsorbent surface. Adsorption mechanism of phosphate ion relates to ion exchange, electrostatic attraction, and surface inner sphere complex formation in this study. Moreover, the phosphate ions adsorbed onto Fe-HT were easily desorbed using sodium hydroxide solution; thus, five cycles of ad-desorption were carried out. Collectively, these results suggest that Fe-HT is promising for the adsorption and recovery of phosphate ions using sodium hydroxide solution.
  • Energy-dependent endocytosis is responsible for drug transcorneal penetration following the instillation of ophthalmic formulations containing indomethacin nanoparticles., Noriaki Nagai, Fumihiko Ogata, Hiroko Otake, Yosuke Nakazawa, Naohito Kawasaki, International journal of nanomedicine, International journal of nanomedicine, 14, 1213 - 1227, 2019 , Refereed
    Summary:Purpose: We previously found that ophthalmic formulations containing nanoparticles prepared by a bead mill method lead to an increase in bioavailability in comparison with traditional formulations (solution type). However, the transcorneal penetration pathway for ophthalmic formulations has not been explained yet. In this study, we investigated the mechanism of transcorneal penetration in the application of ophthalmic formulations containing indomethacin nanoparticles (IMC-NPs). Materials and methods: IMC-NPs was prepared by the bead mill method. For the analysis of energy-dependent endocytosis, corneal epithelial (HCE-T) cell monolayers and removed rabbit cornea were thermoregulated at 4°C, where energy-dependent endocytosis is inhibited. In addition, for the analysis of different endocytosis pathways using pharmacological inhibitors, inhibitors of caveolae-mediated endocytosis (54 µM nystatin), clathrin-mediated endocytosis (40 µM dynasore), macropinocytosis (2 µM rottlerin) or phagocytosis (10 µM cytochalasin D) were used. Results: The ophthalmic formulations containing 35-200 nm sized indomethacin nanoparticles were prepared by treatment with a bead mill, and no aggregation or degradation of indomethacin was observed in IMC-NPs. The transcorneal penetration of indomethacin was significantly decreased by the combination of nystatin, dynasore and rottlerin, and the decreased penetration levels were similar to those at 4°C in HCE-T cell monolayers and rabbit cornea. In the in vivo experiments using rabbits, dynasore and rottlerin tended to decrease the transcorneal penetration of indomethacin (area under the drug concentration - time curve in the aqueous humor [AUCAH]), and the AUCAH in the nystatin-treated rabbit was significantly lower than that in non-treatment group. In addition, the AUCAH in rabbit corneas undergoing multi-treatment was obviously lower than that in rabbit corneas treated with each individual endocytosis inhibitor. Conclusion: We found that three energy-dependent endocytosis pathways (clathrin-dependent endocytosis, caveolae-dependent endocytosis and macropinocytosis) are related to the trans-corneal penetration of indomethacin nanoparticles. In particular, the caveolae-dependent endocytosis is strongly involved.
  • Evaluation of the Interaction between Borate Ions and Nickel-Aluminum Complex Hydroxide for Purification of Wastewater., Fumihiko Ogata, Noriaki Nagai, Megumu Toda, Masashi Otani, Takehiro Nakamura, Naohito Kawasaki, Chemical & pharmaceutical bulletin, Chemical & pharmaceutical bulletin, 67(5), 487 - 492, 2019 , Refereed
    Summary:A new mixed metal hydroxide adsorbent (NA11, molar ratioNi-Al = 1 : 1) was prepared and its physicochemical properties (specific surface area, amount of hydroxyl group, scanning electron microscopy images, X-ray diffraction analysis, elemental distribution, and binding energy) were studied. In addition, the amount of borate ion adsorbed using several adsorbents, including NA11, was evaluated in this study. The specific surface area of and amount of hydroxyl group in NA11 was greater than those of the other studied adsorbents. The amount of borate ion adsorbed showed similar trends to those of the specific surface area and number of hyrdroxyl groups, which indicated that the adsorption mechanism of borate ion was related to the specific surface area and the amount of hydroxyl group. After adsorption, the binding energy of boron B(1s) peaked, and the sulfur peak intensity S(2s) and S(2p) reduced. These results suggest that ion exchange between borate and sulfate ions was one of the adsorption mechanisms. Equilibrium adsorption was reached within 6 h in the case of NA11. These data were fitted into a pseudo-second-order model (r = 0.813-0.998). The solution pH affected the capacity of NA11 for adsorbing borate ion from aqueous solution. It was found that adsorbance was greatest at pH 10. Adsorption isotherm data were fitted to both the Freundlich (r = 0.986-0.994) and Langmuir (r = 0.997-0.999) isotherm equations. Collectively, it is suggested that NA11 is prospectively useful for the adsorption of borate ion from aqueous solutions.
  • Adsorption capability of virgin and calcined wheat bran for molybdenum present in aqueous solution and elucidating the adsorption mechanism by adsorption isotherms, kinetics, and regeneration, Fumihiko Ogata, Takehiro Nakamura, Naohito Kawasaki, JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING, JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING, 6(4), 4459 - 4466, Aug. 2018 , Refereed
    Summary:In this study, we prepared wheat bran (WB), a type of waste biomass, and studied the characteristics of virgin WB and WB calcined at 200, 400, 600, 800, and 1000 degrees C (denoted by WB200, WB400, WB600, WB800, and WB1000). Subsequently, their adsorption isotherms, kinetics, and regeneration were evaluated. Specific surface area of calcined WB is larger compared to that of virgin WB. Amount of molybdenum (Mo) adsorbed is in the following order: WB400 (0 mg/g) = WB600 (0 mg/g) < WB800 (2.9 mg/g) < WB200 (12.9 mg/g) < WB (24.7 mg/g) < WB1000 (29.8 mg/g). The data for adsorption isotherms was applied to both the Freundlich (0.911-0.989) and the Langmuir (0.985-0.992) models. The amount of Mo adsorbed increased with increasing temperature and decreasing pH of the solution. We confirmed that the intensity of Mo on the adsorbent surface was greater after the adsorption treatment than before the treatment. In addition, the amount of Mo adsorbed on virgin WB was greater than that adsorbed on WB treated with different concentrations of hydrochloric acid, which suggests that the adsorption mechanism was related to the three-dimensional protein structure. Finally, adsorbed Mo on WB could be easily desorbed by treatment with sodium hydroxide solution. The recovery percentage of Mo using 1 and 100 mmol/L sodium hydroxide solution is 95.0% and 94.2% respectively. These results indicate that WB has great potential for Mo adsorption from aqueous solutions.
  • Adsorption of Nitrite and Nitrate Ions from an Aqueous Solution by Fe-Mg-Type Hydrotalcites at Different Molar Ratios, Fumihiko Ogata, Noriaki Nagai, Yukine Kariya, Eri Nagahashi, Yuhei Kobayashi, Takehiro Nakamura, Naohito Kawasaki, CHEMICAL & PHARMACEUTICAL BULLETIN, CHEMICAL & PHARMACEUTICAL BULLETIN, 66(4), 458 - 465, Apr. 2018 , Refereed
    Summary:In this study, we prepared Fe-Mg-type hydrotalcites (Fe-HT3.0 and Fe-HT5.0) with different molar ratios and evaluated their adsorption capability for nitrite and nitrate ions from aqueous solution. Fe-HT is a typical hydrotalcite-like layered double hydroxide. Adsorption isotherms, as well as the effects of contact time and pH were investigated, and it was found that Fe-HT can adsorb larger amounts of nitrite and nitrate ions than Al-HT (normal-type hydrotalcite). Adsorption isotherm data were fitted to both Freundlich (correlation coefficient: 0.970-1.000) and Langmuir (correlation coefficient: 0.974-0.999) equations. Elemental analysis and binding energy of Fe-HT surface before and after adsorption indicated that the adsorption mechanism was related to the interaction between the adsorbent surface and anions. In addition, the ion exchange process is related to the adsorption mechanism. The adsorption amount increased with increasing temperature (7-25 degrees C). The experimental data fit the pseudo-second-order model better than the pseudo-first order model. The effect of pH on adsorption was not significant, which suggested that Fe-HT could be used over a wide pH range (4-12). These results indicate that Fe-HT is a good adsorbent for the removal of nitrite and nitrate ions from aqueous solution.
  • Biomass Potential of Virgin and Calcined Tapioca (Cassava Starch) for the Removal of Sr(II) and Cs(I) from Aqueous Solutions, Fumihiko Ogata, Noriaki Nagai, Erimi Ueta, Takehiro Nakamura, Naohito Kawasaki, CHEMICAL & PHARMACEUTICAL BULLETIN, CHEMICAL & PHARMACEUTICAL BULLETIN, 66(3), 295 - 302, Mar. 2018 , Refereed
    Summary:In this study, we prepared novel adsorbents containing virgin and calcined tapioca products for removing strontium (Sr(II)) and cesium (Cs(I)) from aqueous solutions. The characteristics of tapioca, along with its capacity to adsorb Sr(II) and Cs(I), were evaluated. Multiple tapioca products were prepared and tested. The adsorbent prepared by boiling the tapioca followed by calcination at 300 degrees C (BTP300) was the most effective. In addition, adsorption was affected by the adsorbent's surface properties. The Sr(II) and Cs(I) adsorbed onto BTP300 could be recovered through desorption by hydrochloric acid at different concentrations, which indicates that BTP300 can be used several times for adsorption/desorption. The results of this study suggest that BTP300, which was produced from tapioca biomass, can remove Sr(II) and Cs(I) from aqueous solutions.
  • Synergistic cytotoxicity caused by forming a complex of copper and 2,9-dimethyl-1,10-phenanthroline in cultured vascular endothelial cells, Takehiro Nakamura, Eiko Yoshida, Tomoya Fujie, Fumihiko Ogata, Chika Yamamoto, Naohito Kawasaki, Toshiyuki Kaji, JOURNAL OF TOXICOLOGICAL SCIENCES, JOURNAL OF TOXICOLOGICAL SCIENCES, 42(6), 683 - 687, Dec. 2017 , Refereed
    Summary:Organic-inorganic hybrid molecules, which are composed of organic-ligand(s) and metal(s), are indispensable as synthetic reagents in chemistry, but they have made very little in the way of contributions to biological research. Previously, we reported that the cytotoxicity of organic-inorganic hybrid molecules in vascular endothelial cells depends on interactions between the intramolecular metal and ligand, but remains independent of the hydrophobicity of the intramolecular metal(s). Herein, we show a synergistic cytotoxicity produced by forming a complex of copper and 2,9-dimethyl-1,10-phenanthroline in vascular endothelial cells that depends on the intracellular accumulation of copper.
  • Co-instillation of nano-solid magnesium hydroxide enhances corneal permeability of dissolved timolol, Noriaki Nagai, Fumihiko Ogata, Hiroko Otake, Naohito Kawasaki, Yosuke Nakazawa, Kazutaka Kanai, Norio Okamoto, Yoshikazu Shimomura, EXPERIMENTAL EYE RESEARCH, EXPERIMENTAL EYE RESEARCH, 165, 118 - 124, Dec. 2017 , Refereed
    Summary:We prepared magnesium hydroxide (MH) nanoparticles by a bead mill method, and investigated whether the co-instillation of MH nanoparticles improves the low transcorneal penetration of watersoluble drugs, such as the anti-glaucoma eye drug timolol maleate (TM). MH particle size was decreased by the bead mill treatment to a mean particle size of 71 nm. In addition, the MH nanoparticles were highly stable. Next, we demonstrated the effect of MH nanoparticles on the corneal surface. MH shows only slight solubility in lacrimal fluid, and the instillation of MH nanoparticles for 14 days did not affect the behavior (balance of secretion and excretion) of the lacrimal fluid in rabbit corneas. Moreover, there was no observable corneal toxicity of MH nanoparticles, and treatment with MH nanoparticles enhanced the intercellular space ratio in the eyes of rats. MH alone did not permeate into the cornea; however, the co-instillation of MH nanoparticles and dissolved TM (nMTFC) enhanced the corneal penetration of TM. In addition, the intraocular pressure (IOP)-reducing effect of nMTFC was significantly higher than those of the TM solution or the co-instillation of MH microparticles and TM. In conclusion, we found that MH nanoparticles enhance the corneal penetration of dissolved TM with no observable corneal stimulation or obstruction of the nasolacrimal duct by the MH nanoparticles. It is possible that the co-instillation of MH nanoparticles may provide a useful way to improve the bioavailability of watersoluble drugs in the ophthalmic field. These findings provide significant information that can be used to design further studies aimed at developing anti-glaucoma eye drugs. (C) 2017 Elsevier Ltd. All rights reserved.
  • Adsorption of tungsten ion with a novel Fe-Mg type hydrotalcite prepared at different Mg2+/Fe3+ ratios, Fumihiko Ogata, Takehiro Nakamura, Erimi Ueta, Eri Nagahashi, Yuhei Kobayashi, Naohito Kawasaki, JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING, JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING, 5(4), 3083 - 3090, Aug. 2017 , Refereed
    Summary:A novel Fe-Mg type hydrotalcite at different Mg2+/Fe3+ ratio (Fe-HT3.0 and Fe-HT5.0) were prepared, and their properties were investigated by scanning electron microscopy, X-ray diffraction analysis, electron probe microanalysis, specific surface area, and binding energy studies. In addition, the adsorption capability of tungsten onto Fe-HT3.0 and Fe-HT5.0 was evaluated. The amount of tungsten adsorbed onto Fe-HT3.0 and Fe-HT5.0 increased with increasing temperatures. The results of the adsorption isotherm studies suggested that tungsten adsorption can be well described by both the Freundlich (R-2: 0.895-0.998) and Langmuir (R-2: 0.890-0.998) equations. The tungsten adsorbed onto the adsorbent surface was confirmed by electron probe microanalysis and binding energy. The obtained data on thermodynamic parameters showed a decrease in Delta G with the increase in temperature, which indicated that tungsten adsorption was spontaneous. The adsorption of tungsten onto FeHT3.0 and Fe-HT5.0 reached equilibrium within 3 and 10 h, respectively, and the adsorption kinetic data fit the pseudo-second-order kinetic model better than the pseudo-first-order kinetic model. The optimal pH condition for the adsorption of tungsten onto Fe-HT3.0 and Fe-HT5.0 is approximately 2.0. The results of this study indicate that the adsorption mechanism of tungsten onto Fe-HT3.0 and Fe-HT5.0 involves ion exchange, electrostatic attraction, and surface inner-sphere complex formation between tungsten ion and hydroxide ion. Finally, tungsten adsorbed onto the Fe-HT3.0 and Fe-HT5.0 surfaces was desorbed by sodium hydroxide solution at different concentrations. Collectively, these results suggest that Fe-HT3.0 and Fe-HT5.0 can be useful for the adsorption and recovery of tungsten from aqueous solutions.
  • Relationship between Hay Fever and Mineral Concentration in the Hair, Lifestyle or Aging, Kaito Yamashiro, Fumihiko Ogata, Naohito Kawasaki, YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 137(8), 1035 - 1040, Aug. 2017 , Refereed
    Summary:It is important to ingest just proportions of minerals to prevent disease, but these minerals are also secreted into the hair. Meanwhile, the number of hay fever patients in Japan is increasing, causing an increase in national medical expenses. In this study, we investigated the relationship between hay fever and mineral concentrations in hair to obtain findings on the risk of developing pollen allergies. A questionnaire survey was conducted for 275 men and 977 women on their lifestyle habits and ten kinds of mineral concentrations present in their hair were measured with subsequent analysis using nominal logistic regression analysis. The results indicated that half the patients in each age group had hay fever, with no significant difference between hay fever and aging, exercise habits, sleep and dietary rhythms. On the other hand, there was a significant difference between hay fever and mineral concentrations in the hair, and in men with hay fever, iron (odds ratio: 0.55, p < 0.05) was low, while in women calcium (odds ratio: 0.67, p < 0.05), chromium (odds ratio: 0.46, p < 0.001), cadmium (odds ratio: 0.68, p < 0.01) were low and selenium (odds ratio: 1.78, p < 0.01) was high. These results, suggest that measurements mineral concentrations in hair are indicators of hay fever risk.
  • Evaluation of a novel method for measurement of intracellular calcium ion concentration in fission yeast, Fumihiko Ogata, Ryosuke Satoh, Ayako Kita, Reiko Sugiura, Naohito Kawasaki, JOURNAL OF TOXICOLOGICAL SCIENCES, JOURNAL OF TOXICOLOGICAL SCIENCES, 42(2), 159 - 166, Apr. 2017 , Refereed
    Summary:The distribution of metal and metalloid species in each of the cell compartments is termed as "metallome". It is important to elucidate the molecular mechanism underlying the beneficial or toxic effects exerted by a given metal or metalloid on human health. Therefore, we developed a method to measure intracellular metal ion concentration (particularly, intracellular calcium ion) in fission yeast. We evaluated the effects of nitric acid (HNO3), zymolyase, and westase treatment on cytolysis in fission yeast. Moreover, we evaluated the changes in the intracellular calcium ion concentration in fission yeast in response to treatment with/without micafungin. The fission yeast undergoes lysis when treated with 60% HNO3, which is simpler and cheaper compared to the other treatments. Additionally, the intracellular calcium ion concentration in 60% HNO3-treated fission yeast was determined by inductively coupled plasma atomic emission spectrometry. This study yields significant information pertaining to measurement of the intracellular calcium ion concentration in fission yeast, which is useful for elucidating the physiological or pathological functions of calcium ion in the biological systems. This study is the first step to obtain perspective view on the effect of the metallome in biological systems.
  • Combination Ointment Containing Solid Tranilast Nanoparticles and Dissolved Sericin Is Efficacious for Treating Skin Wound-Healing Deficits and Redness in Diabetic Rats, Noriaki Nagai, Fumihiko Ogata, Saori Deguchi, Akina Ueno, Naohito Kawasaki, Yoshimasa Ito, BIOLOGICAL & PHARMACEUTICAL BULLETIN, BIOLOGICAL & PHARMACEUTICAL BULLETIN, 40(4), 444 - 450, Apr. 2017 , Refereed
    Summary:We attempted to design a combination ointment containing solid tranilast nanoparticles and dissolved sericin as a wound-healing drug (TS-combination ointment), and evaluated its usefulness as therapy for wound-healing deficits in streptozotocin-induced diabetic rat (STZ rat) using kinetic analyses as an index. Solid tranilast nanoparticles were prepared by bead mill methods with low-substituted methylcellulose; the mean particle size of the tranilast nanoparticles was 70 nm. The ointment was designed to contain the tranilast nanoparticles plus sericin powder and/or Carbopol 934. Skin wound healing in STZ rats begins significantly later than in normal rats. Although the skin wound healing rate in STZ rats treated with an ointment containing tranilast nanoparticles was lower than in STZ rats treated with vehicle, the ointment was effective' in reducing redness. An ointment containing sericin enhanced the skin-healing rate, but the preventive effect on redness was weak. On the other hand, the combination of tranilast and sericin increased both the skin healing rate and reduction in redness. In conclusion, we have adapted kinetic analyses to skin wound healing in rats, and found these analyses to be useful as an index of wound healing ability by a wound-healing drug. In addition, we show that treatment with the TS-combination ointment enhances the skin wound healing rate and reduces redness. These findings provide information significant to the search for new wound-healing therapies and for the design of wound-healing drugs.
  • Adsorption Capability of Cationic Dyes (Methylene Blue and Crystal Violet) onto Poly-gamma-glutamic Acid, Fumihiko Ogata, Noriaki Nagai, Naohito Kawasaki, CHEMICAL & PHARMACEUTICAL BULLETIN, CHEMICAL & PHARMACEUTICAL BULLETIN, 65(3), 268 - 275, Mar. 2017 , Refereed
    Summary:In this study, the adsorption capability of cationic dyes, which were methylene blue and crystal violet, by poly-gamma-glutamic acid (PGA) in a single or binary solution system was investigated. The effect of the molecular weight of PGA, initial dye concentration, solution pH, and temperature on the adsorption of dyes was evaluated. The adsorption mechanism of dyes onto PGA was the interaction between -COOH group on the PGA surface and the polarity groups of dyes. These results indicated that PGA is useful for removal of dyes and cationic organic compounds from a single or binary solution system.
  • Adsorption of phosphate ions from an aqueous solution by calcined nickel-cobalt binary hydroxide, Fumihiko Ogata, Erimi Ueta, Megumu Toda, Masashi Otani, Naohito Kawasaki, WATER SCIENCE AND TECHNOLOGY, WATER SCIENCE AND TECHNOLOGY, 75(1), 94 - 105, Jan. 2017 , Refereed
    Summary:Different molar ratios of a Ni/Co binary hydroxide (NiCo82, NiCo91, and Ni100) were prepared and calcined at 270 degrees C (NiCo82-270, NiCo91-270, and Ni100-270). The properties of the adsorbents and the amount of adsorbed phosphate ions were evaluated. The adsorbents calcined at 270 degrees C had a nickel oxide structure. The amount of adsorbed phosphate ions, the amount of hydroxyl groups, and the specific surface area of the calcined adsorbents at 270 degrees C were greater than those of the uncalcined adsorbents. The amount of adsorbed phosphate ions was related to the amount of hydroxyl groups and the specific surface area; the correlation coefficients were 0.966 and 0.953, respectively. The adsorption isotherm data for NiCo91 and NiCo91-270 were fit to both the Freundlich and Langmuir equations. The amount of adsorbed phosphate ions increased with increasing temperature. The experimental data fit the pseudo-second-order model better than the pseudo-first-order model. A neutral pH was optimal for phosphate ion adsorption. In addition, the phosphate ions that were adsorbed onto NiCo91-270 could be recovered using sodium hydroxide, and the adsorbent was useful for the repetitive adsorption/desorption of phosphate ions. Collectively, these results suggest that NiCo91-270 is prospectively useful for the adsorption of phosphate ions from aqueous solutions.
  • Regeneration of Waste Edible Oil by the Use of Virgin and Calcined Magnesium Hydroxide as Adsorbents, Fumihiko Ogata, Naohito Kawasaki, JOURNAL OF OLEO SCIENCE, JOURNAL OF OLEO SCIENCE, 65(11), 941 - 948, Nov. 2016 , Refereed
    Summary:In this study, we prepared virgin (S, L) and calcined (S-380, S-1000, L-380, L-1000) magnesium hydroxide for regeneration of waste edible oil. Deterioration of soybean oil, rapeseed oil, and olive oil was achieved by heat and aeration treatment. The properties of the different adsorbents were investigated using specific surface area measurements, scanning electron microscopy, X-ray diffraction analysis, thermogravimetric-differential thermal analysis, and surface pH measurement. Moreover, the relationship between the changes in acid value (AV) and carbonyl value (CV) and the adsorbent properties were evaluated. The specific surface areas of S-380 and L-380 were greater than that of other adsorbents. In addition, the XRD results show that S-380 and L-380 contain both magnesium hydroxide and magnesium oxide structures. The decreases in AV and CV using S-380 and L-380 were greater than achieved using other adsorbents. The correlation coefficients between the decrease in AV and CV and specific surface area were 0.947 for soybean oil, 0.649 for rapeseed oil, and 0.773 for olive oil, respectively. The results obtained in this study suggest that a physical property of the adsorbent, namely specific surface area, was primarily responsible for the observed decreases in AV and CV. Overall, the results suggest that S-380 and L-380 are useful for the regeneration of waste edible oil.
  • Simultaneous removal of phosphate and nitrite ions from aqueous solutions using modified soybean waste, Fumihiko Ogata, Ayaka Ueda, Shigeharu Tanei, Daisuke Imai, Naohito Kawasaki, JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY, JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY, 35, 287 - 294, Mar. 2016 , Refereed
    Summary:We investigated the simultaneous removal of phosphate and nitrite ions from aqueous solutions by a combination treatment that used both PG-Ca (polyl-gamma-glutamic acid combined with flocculating agents) and SB600 (soybeans treated with calcium chloride, hydrochloric acid and calcined at 600 degrees C). Phosphate ions and nitrite ions were selectivity adsorbed by PG-Ca and SB600, respectively. The removal mechanism of phosphate ions from aqueous solution was related to the presence of calcium hydroxide (derived from PG-Ca), and that of nitrite ions was related to the presence of chloride ions at the surface of SB600. (C) 2016 The Korean Society of Industrial and Engineering Chemistry. Published by Elsevier B.V. All rights reserved.
  • Properties of a novel adsorbent produced by calcination of nickel hydroxide and its capability for phosphate ion adsorption, Fumihiko Ogata, Daisuke Imai, Megumu Toda, Masashi Otani, Naohito Kawasaki, JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY, JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY, 34, 172 - 179, Feb. 2016 , Refereed
    Summary:Nickel hydroxide (Ni) was calcined at 270 and 400 degrees C (denoted Ni270 and Ni400), and the properties of Ni, Ni270, and Ni400 were investigated. In addition, the phosphate adsorption capabilities of Ni, Ni270, and Ni400 were evaluated by examination of the effects of contact time and solution pH, analysis of an adsorption isotherm, and study of desorption. The amounts of phosphate ion adsorbed by the different samples showed the order Ni < Ni400 < Ni270. Finally, phosphate ions adsorbed onto Ni270 could be desorbed using sodium hydroxide, indicating that Ni270 can be used as a renewable adsorbent. (C) 2015 The Korean Society of Industrial and Engineering Chemistry. Published by Elsevier B.V. All rights reserved.
  • Increased Expression of Interleukin-18 in Lenses of Ovariectomized Rats, Noriaki Nagai, Fumihiko Ogata, Naohito Kawasaki, Yoshimasa Ito, BIOLOGICAL & PHARMACEUTICAL BULLETIN, BIOLOGICAL & PHARMACEUTICAL BULLETIN, 39(1), 138 - 142, Jan. 2016 , Refereed
    Summary:Previous studies showed an increased prevalence of cataracts in postmenopausal women. In this study, we investigated changes in the levels of calcium ion (Ca2+) and interleukin (IL)-18, which are factors in cataract development, in the lenses of ovariectomized (OVX) rats, a model of postmenopausal woman. Although the Ca2+ content in the blood of OVX rats increased 1 month after ovariectomy and subsequently decreased, the Ca2+ content in the lenses was unchanged in OVX rats 1-3 months after ovariectomy. The Ca2+-ATPase activity in the lenses of OVX rats peaked 1 month after ovariectomy, and the behavior of Ca2+-ATPase activity in lenses of OVX rats was similar to that of the Ca2+ concentration in the blood. It is possible that hypercalcemia increases the Ca2+ inflow into the lens; however, the enhanced Ca2+-ATPase activity prevents the Ca2+ level from rising. On the other hand, we found that the levels of both IL-18 and interferon (IFN)-y in the lenses of OVX rats were significantly increased as compared with the lenses of sham (control) rats during the period 1-3 months after surgery. These results suggest that the expression of IFN-gamma via IL-18 in the lenses of OVX rats is induced by ovariectomy, and that excessive IL-18 and IFN-gamma production in the lenses may be related to cataract development in postmenopausal women. These findings support those of previous studies that assessed lens opacification in postmenopausal women.
  • Adsorption of As(III) from Aqueous Solutions by Novel Fe-Mg Type Hydrotalcite, Fumihiko Ogata, Naohito Kawasaki, CHEMICAL & PHARMACEUTICAL BULLETIN, CHEMICAL & PHARMACEUTICAL BULLETIN, 63(12), 1040 - 1046, Dec. 2015 , Refereed
    Summary:Morphological and chemical evaluation of Fe-Mg hydrotalcite (Fe-HT) was performed using scanning electron microscopy, X-ray diffraction analysis, and electron microanalysis for application as an adsorbent for water treatment. The adsorption of arsenic III (As(III)) on Fe-HT was evaluated via examination of the effect of the contact time and analysis of the adsorption isotherm. The amount of As(III) adsorbed increased slightly with increasing temperature. The results of the adsorption isotherm studies suggested that As(III) adsorption can be well described by both the Freundlich and Langmuir equations. The adsorption of As(III) on Fe-HT reached equilibrium within 24 h, and the adsorption kinetic data fit the pseudo-second-order kinetic model better than the pseudo-first-order model. The amount of As(III) present on the surface of Fe-HT increased after As(III) adsorption, and the crystalline structure of Fe-HT was maintained after adsorption of As(III). The (003) and (006) peaks in the X-ray diffraction patterns were attributed to basal reflections, and these peaks shifted from respective 2 theta values of 10.86 and 21.94 degrees to 11.12 and 22.52 degrees, indicating exchange of As(III) with chloride ions in Fe-HT with consequent narrowing of the inter-layer spacing. Collectively, these results suggest that Fe-HT is prospectively useful for the adsorption of As(III) from aqueous solutions.
  • Hypercalcemia Leads to Delayed Corneal Wound Healing in Ovariectomized Rats, Noriaki Nagai, Fumihiko Ogata, Naohito Kawasaki, Yoshimasa Ito, Yoshinori Funakami, Norio Okamoto, Yoshikazu Shimomura, BIOLOGICAL & PHARMACEUTICAL BULLETIN, BIOLOGICAL & PHARMACEUTICAL BULLETIN, 38(7), 1063 - 1069, Jul. 2015 , Refereed
    Summary:Hypercalcemia is often observed in postmenopausal women as well as in patients with primary hyperparathyroidism or malignant tumors. In this study, we investigated the relationship between calcium ion (Ca2+) levels in lacrimal fluid and the rate of corneal wound healing in hypercalcemia using ovariectomized (OVX) rat debrided corneal epithelium. We also determined the effects of Ca2+ levels on cell adhesion, proliferation and viability in a human cornea epithelial cell line (HCE-T). The calcium content in bones of OVX rats decreased after ovariectomy. Moreover, the Ca2+ content in the blood of OVX rats was increased 1 month after ovariectomy, and decreased. The Ca2+ content in the lacrimal fluid of OVX rats was also increased after ovariectomy, and then decreased similarly as in blood. Corneal wound healing in OVX rats was delayed in comparison with Sham rats (control rats), and a close relationship was observed between the Ca2+ levels in lacrimal fluid and the rate of corneal wound healing in Sham and OVX rats (y=-0.7863x+8.785, R=0.78, n=25). In addition, an enhancement in Ca2+ levels caused a decrease in the viability in HCE-T cells. It is possible that enhanced Ca2+ levels in lacrimal fluid may cause a decrease in the viability of corneal epithelial cells, resulting in a delay in corneal wound healing. These findings provide significant information that can be used to design further studies aimed at reducing corneal damage of patients with hypercalcemia.
  • Adsorption of Tungsten onto Zeolite Fly Ash Produced by Hydrothermally Treating Fly Ash in Alkaline Solution, Fumihiko Ogata, Yuka Iwata, Naohito Kawasaki, CHEMICAL & PHARMACEUTICAL BULLETIN, CHEMICAL & PHARMACEUTICAL BULLETIN, 62(9), 892 - 897, Sep. 2014 , Refereed
    Summary:Fly ash (FA) was hydrothermally treated in an alkaline solution to produce zeolite fly ash (Z-FA). The properties of the FA and Z-FA were investigated. The amounts of tungsten (W) adsorbed onto the FA and Z-FA surfaces were evaluated. Z-FA was produced by hydrothermally treating FA in an alkaline solution. The specific surface area and pore volume of the Z-FA were greater than those of the FA. More W was adsorbed onto the Z-FA surface than onto the FA surface. The adsorption isotherms for W were fitted using both the Freundlich and Langmuir equations. The equilibrium concentrations of W adsorbed onto the FA and Z-FA surfaces were subsequently reached within 20h. The pseudo-second-order model more accurately described the data than did the pseudo-first-order model. Sodium hydroxide solutions (1-50 mmol/L) were used to easily recover W from Z-FA, indicating that Z-FA was useful for recovering W from aqueous solutions.
  • Adsorption of Orthophosphoric, Pyrophosphoric, and Tripolyphosphoric Acids from Aqueous Solutions by Calcined Gibbsite, Fumihiko Ogata, Ayaka Ueda, Naohito Kawasaki, CHEMICAL & PHARMACEUTICAL BULLETIN, CHEMICAL & PHARMACEUTICAL BULLETIN, 62(8), 799 - 805, Aug. 2014 , Refereed
    Summary:In this research, gibbsite (GB) samples calcined at 200-1000 degrees C (GB200-GB1000) were produced. These GBs were used to adsorb orthophosphoric, pyrophosphoric, and tripolyphosphoric acids from aqueous solutions. The properties (amounts of hydroxyl groups, specific surface areas, mean pore diameters, and solution pHs) of the GBs were investigated, and their adsorption capacities for phosphoric acids evaluated. The amount of hydroxyl groups (0.46 mmol/g) and specific surface area (295.3 m(2)/g) of GB400 were greater than those of the other GBs. The mechanism of phosphoric acid adsorption on the GBs was related to the amount of hydroxyl groups and specific surface area. The optimal pH for phosphoric acid adsorption by GBs was 2.0-3.0. Equilibrium adsorption was reached within 24h. The adsorption processes followed a pseudo-second-order kinetic model (correlation coefficient, 0.998-0.999). The adsorption capacity increased with increasing temperature. The adsorption isotherm data fitted the Langmuir (correlation coefficient: 0.921-0.992) and Freundlich (correlation coefficient: 0.948-0.997) equations well. Our results will be useful when developing methods for the adsorption of phosphoric acids from aqueous solutions.
  • Fundamental Study on Effect of High-mineral Drinking Water for Osteogenesis in Calciprivia Ovariectomized Rats, Fumihiko Ogata, Noriaki Nagai, Yoshimasa Ito, Naohito Kawasaki, YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 134(5), 679 - 685, May 2014 , Refereed
    Summary:Since osteoporosis is a major public health problem in Japan, it is important to clarify the effect of high-mineral drinking water consumption on osteogenesis. Therefore, in this study, we investigated the relationship between high-mineral drinking water consumption and osteogenesis in ovariectomized rats that received a low-calcium diet and purified water (PW group) or a low-calcium diet and high-mineral drinking water (CR group). High-mineral drinking water affected the rats' body weight. After 3 months, the bone density of the CR group was higher than that of the PW group (p<0.05). Furthermore, the CR group showed a decrease in the amount of calcium in the bones after 3 months. These results suggest that high-mineral drinking water contributes to the maintenance of bone density and not to the amount of calcium in bone. On the other hand, serum alkaline phosphatase levels in the PW group at 3 months were higher than those in the CR group, which indicates that the blood concentration of calcium in the CR group was maintained. Moreover, the amount of magnesium in the bones and the blood concentration of magnesium in the CR group after 3 months were higher than the corresponding values in the PW group. These results suggest that consumption of high-mineral drinking water could be beneficial for osteogenesis (i.e., for maintaining bone quantity)
  • A Study on the Adsorption of Heavy Metals by Using Raw Wheat Bran Bioadsorbent in Aqueous Solution Phase, Fumihiko Ogata, Moe Kangawa, Yuka Iwata, Ayaka Ueda, Yuko Tanaka, Naohito Kawasaki, CHEMICAL & PHARMACEUTICAL BULLETIN, CHEMICAL & PHARMACEUTICAL BULLETIN, 62(3), 247 - 253, Mar. 2014 , Refereed
    Summary:Raw wheat bran (R-WB) was used as a biomass adsorbent. The properties of R-WB were investigated. Moreover, the adsorption of cadmium and lead ions onto R-WB was evaluated. Adsorption equilibrium of cadmium and lead ions onto R-WB was achieved within 10h, indicating that the adsorption followed a pseudo-second-order model rather than a pseudo-first-order kinetic model. The adsorption amount increased with increasing temperature. Correlation coefficient of the Langmuir equation is 0.999 for cadmium and 0.996 for lead ions, and that of the Freundlich equation is 0.994 for cadmium and 0.993 for lead ions. The negative Delta G value implied that the adsorption of cadmium and lead ions onto R-WB is a spontaneous process. The positive Delta S value indicated an increase in randomness at the solid-liquid interface. The optimal conditions for the adsorption column experiment were investigated (space velocity (SV) 2.2 1/h, linear velocity (LV) 0.1 m/h for cadmium; SV 6.511/h, LV 0.23 m/h for lead ions). Further, repeated adsorption-desorption of the cadmium and lead ions could be effected by using 0.01 mol/L HC1 or 0.01 mol/L HNO3 solution. Consequently, polluted water could be successfully purified by using a column filled with this bioadsorbent.
  • Effect of Tocopherol Treatment on Deterioration of Edible Oil Quality (Acid Value, Carbonyl Value, Free Fatty Acid and Radical Activity), Fumihiko Ogata, Yuko Tanaka, Naohito Kawasaki, JOURNAL OF OLEO SCIENCE, JOURNAL OF OLEO SCIENCE, 63(2), 187 - 191, Feb. 2014 , Refereed
    Summary:In this study, waste edible oil was prepared by both heat and aeration treatment, and the increasing inhibitive effect of tocopherol treatment on the acid value (AV) and carbonyl value (CV) of the oil was investigated. The AV and CV of waste edible oil treated with tocopherol were 0.1-1.0% lower than those of the nontreated oil, indicating that tocopherol exerted a radical-scavenging activity. The concentration of tocopherol decreased with time, while that of the remaining 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals increased. These results suggest that the addition of tocopherol proved to be useful for preventing the deterioration of waste edible oil.
  • Team-based Learning (TBL) in the Interdisciplinary Lecture, Keiji Nishiwaki, Atsushi Kawase, Tetsuyuki Wada, Hideki Yagi, Naohito Kawasaki, Eiji Ito, Masahiro Iwaki, YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 134(2), 171 - 177, Feb. 2014 , Refereed
    Summary:We conducted team-based learning (TBL) with interdisciplinary lectures as a part of "Introduction to Pharmacy", divided among the pharmacy department's six pharmacist education curricula in the first semester. The interdisciplinary lecture is led by seven lecturers, each specializing in one area: cell biology, biochemistry, chemistry, public health pharmacology, pharmacokinetics, and clinical science. This lecture's purpose is to demonstrate to the students that all field subjects relate to each other and they must learn the basic science subjects to understand pharmaceutical sciences. The TBL contents have two themes, "cancer" and "aspirin", each of which had two lectures, each 90 minutes long and were conducted using TBL as expansive learning. On receiving knowledge of a wide range of fields in one lecture, a small number of students indicated that they were unable to understand the contents very well. However, in the questionnaire about TBL, many students reported "I have understood" and "I have enjoyed studying" using TBL, especially group readiness assessment test (GRAT). By incorporating TBL, they reported "increasing eagerness to learn pharmacy". Overall, students seem to have accepted TBL favorably, but they still find peer review difficult. We believe that their discomfort with peer review results from their unfamiliarity in evaluating others, and the time before the evaluation is short because TBL is conducted only twice.
  • Study of Adsorption Mechanism of Heavy Metals onto Waste Biomass (Wheat Bran), Fumihiko Ogata, Moe Kangawa, Hisato Tominaga, Yuko Tanaka, Ayaka Ueda, Yuka Iwata, Naohito Kawasaki, JOURNAL OF OLEO SCIENCE, JOURNAL OF OLEO SCIENCE, 62(11), 949 - 953, Nov. 2013 , Refereed
    Summary:In this study, raw wheat bran (R-WB), a type of waste biomass (WB) was treated with Pectinase PL (P-WB), and the properties (yield percentage, carboxy group surface concentration, the solution pH, and specific surface area) of R-WB and P-WB were investigated. The surface concentration of carboxy groups on R-WB (3.56 mmol/g) was greater than that of P-WB (2.11 mmol/g). In contrast, the specific surface area of P-WB (24.98 m(2)/g) was greater than that of R-WB (3.25 m(2)/g). In addition, the adsorption of cadmium and lead ions to WB was evaluated. Adsorption of the heavy-metal ions reached equilibrium within 9 h, and the experimental data was fitted to a pseudo-second-order model. More heavy-metal ions were adsorbed onto R-WB than onto P-WB. The correlation coefficient between the amount of ions adsorbed and the number of carboxy groups or pectin exceeded 0.884 and 0.975, respectively. This study indicated that wheat bran was useful for the removal of cadmium or lead ions from aqueous solutions. The adsorption mechanism of cadmium and lead ions to WB was associated with presence of carboxy group in pectin.
  • Development of Actual Dyestuff Wastewater Treatment by Ozone with Carbonaceous Materials Produced from Waste Fiber, Naohito Kawasaki, Hisato Tominaga, Fumihiko Ogata, SEN-I GAKKAISHI, SEN-I GAKKAISHI, 69(7), 125 - 131, Jul. 2013 , Refereed
    Summary:The methylene blue and dyestuff removal efficiency in a textile factory by ozonation and/or carbonaceous material treatment was investigated. Three kinds of carbonaceous materials were prepared from wool (WL), polyester (PET), and cotton (CT) discharged from the textile factory. The physical properties of the carbonaceous materials were very different. The specific surface area and pore volume of WL were the lowest, while those of CT were the highest. The dyestuff removal efficiency from actual dyestuff water was the highest when using the carbonaceous material (CT) prepared from cotton waste fiber. The decreases in the chromaticity, turbidity, COD, and TOC of the actual dyestuff wastewater depended upon the mean pore diameter of the carbonaceous material. The COD and TOC of the actual dyestuff wastewater were only slightly decreased by ozonation. The ozonation with CT would be useful for the removal of the dyestuff from actual textile wastewater. These results indicated that the waste cotton fiber could be converted into a carbonaceous material as an adsorbent for the removal of dyestuff from actual wastewater.
  • Application of Activated Carbons from Coal and Coconut Shell for Removing Free Residual Chlorine, Fumihiko Ogata, Hisato Tominaga, Ayaka Ueda, Yuko Tanaka, Yuka Iwata, Naohito Kawasaki, JOURNAL OF OLEO SCIENCE, JOURNAL OF OLEO SCIENCE, 62(4), 241 - 244, Apr. 2013 , Refereed
    Summary:This study investigated the removal of free residual chlorine by activated carbon (AC). ACs were prepared from coal (AC1) and coconut shell (AC2). The specific surface area of AC1 was larger than that of AC2. The removal of free residual chlorine increased with elapsed time and amount of adsorbent. The removal mechanism of free residual chlorine was the dechlorination reaction between hypochlorous acid or hypochlorite ion and AC. Moreover, AC1 was useful in the removal of free residual chlorine in tap water. The optimum condition for the removal of free residual chlorine using a column is space velocity 306 1/h; liner velocity 6.1 m/h.
  • Study on analysis of waste edible oil with deterioration and removal of acid value, carbonyl value, and free fatty acid by a food additive (calcium silicate), Fumihiko Ogata, Yuko Tanaka, Hisato Tominaga, Moe Kangawa, Kenji Inoue, Ayaka Ueda, Yuka Iwata, Naohito Kawasaki, JOURNAL OF OLEO SCIENCE, JOURNAL OF OLEO SCIENCE, 62(2), 109 - 114, Feb. 2013 , Refereed
    Summary:This study investigated the regeneration of waste edible oil using a food additive (calcium silicate, CAS). Waste edible oil was prepared by combined heat and aeration treatment. Moreover, the deterioration of edible oil by combined heat and aeration treatment was greater than that by heat treatment alone. The acid value (AV) and carbonyl value (CV) increased with increasing deterioration; conversely, the tocopherol concentration decreased with increasing deterioration. The specific surface area, pore volume, and mean pore diameter of the 3 CAS formulations used (CAS30, CAS60, and CAS90) were evaluated, and scanning electron microscopic images were taken. The specific surface area increased in the order of CAS30 (115.54 m(2)/g) < CAS60 (163.93 m(2)/g) < CAS90 (187.47 m(2)/g). The mean pore diameter increased in the order of CAS90 (170.59 angstrom) < CAS60 (211.60 angstrom) < CAS30 (249.70 angstrom). The regeneration of waste edible oil was possible with CAS treatment. The AV reduced by 15.2%, 10.8%, and 23.1% by CAS30, CAS60, and CAS90 treatment, respectively, and the CV was reduced by 35.6%, 29.8%, and 31.3% by these 3 treatments, respectively. Moreover, the concentrations of tocopherol and free fatty acids did not change with CAS treatment. The characteristics of CAS were not related to the degree of change of AV and CV. However, the adsorption mechanism of polar and non-polar compounds generated in waste edible oil by CAS was related with the presence of silica gel molecules in CAS. The findings indicated that CAS was useful for the regeneration of waste edible oil.
  • Development of Novel Carbon Fiber produced from Waste Fiber by Cabonization, Naohito Kawasaki, Hisato Tominaga, Fumihiko Ogata, Kenji Inoue, Moe Kankawa, JOURNAL OF OLEO SCIENCE, JOURNAL OF OLEO SCIENCE, 61(10), 593 - 600, Oct. 2012 , Refereed
    Summary:The volume of waste fiber has increased rapidly in recent years, and this trend is expected to continue. In this study, therefore, we attempted to convert waste fiber to carbonaceous materials by carbonization and investigated the basic properties of the resulting carbonized fibers. The results demonstrated that pores tend to form and specific surface areas change substantially, depending on the carbonization conditions. The carbonization conditions resulting in the largest specific surface areas included a temperature increase and retention times of 2 h. Carbonization temperatures resulting in the maximum values of 1000 degrees C were 900-1000 degrees C for wool and 1000 degrees C for both polyester and cotton. In particular, the specific surface area of cotton after carbonization at 1000 degrees C was 1253 m(2)/g, and scanning electron microscopy (SEM) micrographs showed that cotton retained its fibrous form after carbonization. Thus, it is possible to inexpensively convert waste fibers to carbonaceous material by carbonization. The results indicate that for cotton fiber in particular, the practical application of this process to the production of low-cost fibrous activated carbon would be possible, since cotton fiber retains its fibrous form under carbonization.
  • Characteristics of Granular Boehmite and Its Ability to Adsorb Phosphate from Aqueous Solution, Fumihiko Ogata, Hisato Tominaga, Moe Kangawa, Kenji Inoue, Naohito Kawasaki, CHEMICAL & PHARMACEUTICAL BULLETIN, CHEMICAL & PHARMACEUTICAL BULLETIN, 60(8), 985 - 988, Aug. 2012 , Refereed
    Summary:In this study, we investigated the surface properties of granulated boehmite with vinyl acetate (G-BE20) and measured the amount of phosphate it adsorbed and the effect of contact time and solution pH on the adsorption process. The specific surface area (144.9 m(2)/g) and the number of surface hydroxyl groups (0.88 mmol/g) of G-BE20 were smaller than those of virgin boehmite (BE), which gave a specific surface area and number of surface hydroxyl groups of 297.0 m(2)/g and 1.08mmol/g, respectively. The amount of phosphate adsorbed increased with the temperature. The isotherm model of Langmuir was used to fit experimental adsorption equilibrium data for phosphate adsorption onto G-BE20. The calculated thermodynamic parameters show the spontaneous and endothermic nature of the adsorption process. The equilibrium adsorption onto G-BE20 was reached within 16h and the amount of phosphate adsorbed was 8.4 mg/g. The kinetic mechanism of phosphate uptake was evaluated with two different models: the Largergren pseudo first- and pseudo second-order models. The data obtained showed a better fit to the pseudo second-order model (0.991) than to the pseudo first-order model (0.967), as indicated by the r values. The rate constants for the adsorption of phosphate onto G-BE20 were calculated as 0.4811/h and 0.029g/mgh. The adsorption of phosphate onto G-BE20 was the maximum in the pH range 3.0-4.0.
  • Removal of Sulfa Drugs by Sewage Treatment in Aqueous Solution Systems: Activated Carbon Treatment and Ozone Oxidation, Fumihiko Ogata, Hisato Tominaga, Moe Kangawa, Kenji Inoue, Naohito Kawasaki, JOURNAL OF OLEO SCIENCE, JOURNAL OF OLEO SCIENCE, 61(4), 217 - 225, Apr. 2012 , Refereed
    Summary:This study investigates the activated carbon (AC) treatment and ozone oxidation of the sulfa drugs - sulfamethoxazole (SMX), sulfamonomethoxine (SMM), sulfadimidine (SDD), and sulfadimethoxine (SDM) - in aqueous solution systems. Three AC samples were prepared from Shirasagi (AC1 and AC2) and coal (AC3), and the surface functional groups, solution pH, specific surface areas, pore volumes, and morphologies of the three samples were evaluated. The specific surface areas were in the following order: AC! (1391 m(2)/g) > AC2 (1053 m(2)/g) > AC3 (807 m(2)/g). The pore volume and mean pore diameter of AC3 were greater than those of AC1 and AC2. The concentration of sulfa drugs adsorbed onto the AC samples reached equilibrium within 150 h. Experimental data of the adsorption rate were fitted to a pseudo-second-order model. The amount of sulfa drugs adsorbed onto the AC samples was in the order of SUM < SMM < SDD < SMX; the mechanism of adsorption of the sulfa drugs onto the AC samples depended on the hydrophobicity of the AC surface. The adsorption isotherm data were fitted to Freundlich and Langmuir models. Ozone was generated from oxygen gas using an A-27 ozone generator, and the complete degradation of the sulfa drugs by ozone treatment at 60 mL/min was achieved within 50 min. Ozone treatment caused the structure of the sulfa drugs to decompose via ozone oxidation.
  • Adsorption Capacity of Cu (II) and Pb (II) onto Carbon Fiber Produced from Wool, Fumihiko Ogata, Hisato Tominaga, Moe Kangawa, Kenji Inoue, Naohito Kawasaki, JOURNAL OF OLEO SCIENCE, JOURNAL OF OLEO SCIENCE, 61(3), 149 - 154, Mar. 2012 , Refereed
    Summary:The potential utility of the widely available waste product, wool textiles, in the adsorption of heavy metals from industrial and other wastewater systems was investigated by proxy experimentation. Carbon fiber was prepared from dyed wool (DW) by calcination at different temperatures (400, 600, 800, and 1000 degrees C, referred to as DW400, DW600, DW800, and DW1000, respectively). The samples were analyzed in terms of scanning electron microscope images, percentage yield, specific surface area, pore volume, and the pH of an aqueous suspension of virgin dyed wool (V-DW) or the calcined DW. The adsorption of Cu (II) and Pb (II) from aqueous solutions was studied using the batch method, and the effect of contact time and co-existence of metal ions was investigated. Cu (II) and Pb (11) adsorption increased with increasing DW calcination temperature in the order V-DW < DW400 < DW600 < DW800 < DW1000. The maximum equilibrium adsorption of Cu (II) and Pb (11) achieved with DW1000 (79% and 57%, respectively) was reached within 6 h. Fitting of the adsorption isotherm data for Cu (11) and Pb (II) adsorption onto DW1000 to the Freundlich equation was consistent with monomolecular adsorption onto a heterogeneous surface. The rate-limiting step was determined to be chemical sorption by fitting the adsorption kinetics data to pseudo first-order and pseudo second-order models, given that the pseudo second-order model best fit our data. The study demonstrated that DW1000 was useful for purification of wastewater containing Cu (II) and Pb (II).
  • Removal of Estrogens from Water Using Activated Carbon and Ozone, Fumihiko Ogata, Hisato Tominaga, Hitoshi Yabutani, Naohito Kawasaki, JOURNAL OF OLEO SCIENCE, JOURNAL OF OLEO SCIENCE, 60(12), 609 - 611, Dec. 2011 , Refereed
    Summary:Estrogens (estron: E1; estradiol: E2; estriol: E3) are major water pollutants. For the removal of estrogens, activated carbon (AC) and ozone treatments were employed, and the chemical oxygen demand (COD) and pH of a single solution and multiple solution systems were investigated. The removal of estrogens increased with the amount of AC. The percentage of removed estrogens by AC in the single solution system was greater than that in the ternary solution system. The estrogens were completely removed using ozone, which also reduced COD and pH. The removal of estrogens increased the water quality and decreased the amount of organic carbon.
  • Removal of Fluoride Ions from Water by Adsorption onto Carbonaceous Materials Produced from Coffee Grounds, Fumihiko Ogata, Hisato Tominaga, Hitoshi Yabutani, Naohito Kawasaki, JOURNAL OF OLEO SCIENCE, JOURNAL OF OLEO SCIENCE, 60(12), 619 - 625, Dec. 2011 , Refereed
    Summary:Carbonaceous material for the removal of fluoride ions from water was prepared from coffee grounds (CGs) by calcination and subsequent HCl treatment. The characteristics of the CGs, including the surface area, mean pore diameter, pore volume, and surface functional groups were determined, and the morphological characteristics were evaluated using scanning electron microscopy. The adsorption isotherms, saturated amount of fluoride ions adsorbed, and the effect of contact time and temperature on the adsorption of fluoride ions were investigated for a sample of tap water. The specific surface area of CG calcined at 600 degrees C (CG600) was larger than that of CGs calcined at 400, 800, and 1000 degrees C. Phenolic, lactonic, and carboxyl groups were detected on the CG600 surface. The adsorption capacity of the carbonized CGs for fluoride was ranked in the order CG400 < CG1000 < CG800 < CG600 (where the numeral indicates the carbonization temperature), whereas virgin CG and CG600-NAT (not treated with hydrochloric acid solution) did not exhibit any adsorption ability for fluoride ions. The amount of fluoride ions adsorbed onto CG600 increased with increasing temperature and was consistent with chemical adsorption. The mechanism of adsorption of fluoride ions onto CG600 proceeded via ion exchange with chloride ions (1:1) present on the surface of CG600. The adsorption isotherms were fitted to the Freundlich and Langmuir equations. Moreover, CG600 showed an acceptable adsorption capacity for fluoride ions present in tap water.
  • Adsorption of Cadmium Ions by Wheat Bran Treated with Pectinase, Fumihiko Ogata, Hisato Tominaga, Moe Kangawa, Naohito Kawasaki, CHEMICAL & PHARMACEUTICAL BULLETIN, CHEMICAL & PHARMACEUTICAL BULLETIN, 59(11), 1400 - 1402, Nov. 2011 , Refereed
    Summary:In this study, we investigated the surface properties of raw wheat bran (R-WB) and wheat bran treated with Pectinase PL (P-WB) to evaluating its efficacy for removal of cadmium from waste water. The concentration of cadmium ions adsorbed by them was evaluated. The concentration of carboxyl groups of R-WB (3.56 mmol/g) was greater than that of P-WB (2.11 mmol/g), which indicated that the pectin of R-WB was broken down, resulting in a decrease in the concentration of carboxyl groups due to the enzyme treatment. From the scanning electron microscope (SEM) images of P-WB, the pores were newly generated with enzyme treatment. The concentration of cadmium ions adsorbed onto R-WB was greater than that of cadmium ions adsorbed onto P-WB. These results show that the adsorption mechanism of cadmium ions onto R-WB and P-WB depends on the carboxyl groups of pectin.
  • Adsorption Mechanism of Copper and Cadmium onto Defatted Waste Biomass, Fumihiko Ogata, Hisato Tominaga, Hitoshi Yabutani, Naohito Kawasaki, JOURNAL OF OLEO SCIENCE, JOURNAL OF OLEO SCIENCE, 60(7), 363 - 368, Jul. 2011 , Refereed
    Summary:In this study, the amount of copper or cadmium adsorbed using waste biomass (i.e., coffee grounds (CG) and rice bran (RB)) was investigated. The amount of crude protein in defatted CG (D-CG) or RB (D-RB) was greater than that in CG or RB, respectively. The amount of copper or cadmium adsorbed using CG was greater than that using RB. Additionally, the amount of copper or cadmium adsorbed was not affected by the presence of fat in CG. Adsorption data was fitted to the Freundlich equation, and the correlation coefficients were in the range of 0.794-0.991. The main adsorption mechanism was thought to be monolayer adsorption onto the surface of the waste biomass. The adsorption rate data was fitted to the pseudo-second-order model, and the correlation coefficient average was in the range of 0.891-0.945. This result showed that the rate-limiting step may be chemisorption. Moreover, the amount of copper or cadmium desorbed from CG or RB using 0.01 mol/L or 1.00 mol/L HNO3 was investigated. Desorption with 0.01 mol/L HNO3 resulted in the recovery of 86-97% of the copper and cadmium, indicating that copper or cadmium that was adsorbed using waste biomass was recoverable.
  • Phosphate Adsorption Ability of Granular Gibbsite and Cerium Hydroxide, Fumihiko Ogata, Hisato Tominaga, Hitoshi Yabutani, Naohito Kawasaki, JOURNAL OF OLEO SCIENCE, JOURNAL OF OLEO SCIENCE, 60(3), 133 - 138, Mar. 2011 , Refereed
    Summary:In the present study, the phosphate adsorption abilities of granular materials, gibbsite (GB) and cerium hydroxide (CE), granulated with ethyl cellulose and ethanol, were investigated. For suitable granular conditions using GB or CE, the percentage of binder and amount of solvent were 10% and 3.25 mL/5 g for GB and 7.5% and 2.50 mL/5 g for CE. The amount of phosphate adsorbed by granular GB or CE was similar to that adsorbed by powdered GB or CE. The adsorption isotherms of phosphate were also similar for the granular and powdered materials. The results of a column experiment showed that when GB was used, the suitable concentration of sodium hydroxide as the desorption solution was 2 mmol/L. In these experiments, the amount of phosphate adsorbed was 31.4 mg/g, the amount of phosphate desorbed was 25.3 mg/g, and the recovery percentage was 80.5%. In contrast, when CE was used, the suitable concentration of sodium hydroxide was 500 mmol/L; the amount of phosphate adsorbed was 77.7 mg/g, the amount of phosphate desorbed was 57.8 mg/g, and the recovery percentage was 74.4%. Results also indicate that granular GB and CE could be used at least five times in a column without loss of absorption or desorption abilities. Moreover, granulation of GB and CE is possible using ethyl cellulose and ethanol.
  • Recovery of molybdenum from fly ash by gibbsite, Fumihiko Ogata, Hisato Tominaga, Hitoshi Yabutani, Atsushi Taga, Naohito Kawasaki, TOXICOLOGICAL AND ENVIRONMENTAL CHEMISTRY, TOXICOLOGICAL AND ENVIRONMENTAL CHEMISTRY, 93(4), 635 - 642, 2011 , Refereed
    Summary:The effectiveness of gibbsite (GB), an amorphous aluminum oxide, for the recovery of Mo(VI) from eluates of fly ash of two coal-fired thermal power stations and of roof tile waste was investigated. Upon the qualitative analysis of an eluate of fly ash, 16 elements were detected. Greater amounts of these elements were eluted under acidic conditions (pH 2) than from the neutral or basic eluate of fly ash. GB was used for the adsorption of Mo(VI). Equilibrium adsorption was reached within 1 min. Optimal solution acidity for the adsorption of Mo(VI) onto GB400 (calcined at 400 degrees C) was pH 2. The main adsorption mechanism was ion exchange with a number of hydroxyl groups of GB400. For repeated ad- and desorption of Mo(VI), GB400 could be used at least four times and the recovery percentage of Mo(VI) with sodium hydroxide solution as eluent surpassed 90%. Our results showed that GB400 was very effective for the recovery of Mo(VI) from fly ash.
  • A Trial of the Integrated Cross-field Pharmaceutical Education in the First Year of Faculty of Pharmacy, Tomohisa Yasuhara, Naohito Kawasaki, Hideki Yagi, Eiji Itoh, Atsushi Kawase, Toru Otori, Tetsuyuki Wada, Kenji Matsuyama, Masahiro Iwaki, YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 130(12), 1647 - 1653, Dec. 2010 , Refereed
    Summary:The six-year pharmacist education course has begun, and now first-year students receive clinical training. Interdisciplinary problem-solving capabilities covering chemistry, biology, molecular biology, pharmacology, pathology, and pharmacokinetics are necessary for new pharmacists. However, the conventional pharmaceutical science education was so separate from other fields that education for interdisciplinary cooperative capability was insufficient. This was especially true of elemental science courses, because they are not directly connected with clinical knowledge, and there is a problem of low student interest in those courses. As a result, students acquired only recall-level knowledge in clinical courses and their problem-solving capabilities in clinical treatment and drug development deteriorated. Therefore we offered a trial lecture aimed to help students recognize the important relationship between elemental science courses and clinical courses and increase their motivation to enroll in these courses. Specifically, the trial lecture covered cancer therapy, in reference to mechanisms of carcinogenesis, epidemiology, physiology of cancer, anticancer drugs with explanations of the mechanism of action of carcinogens, anticancer drugs, and molecular-targeted drugs from the viewpoints of organic chemistry and biochemistry by a specialized teacher. This paper reports on this experimental lecture with evaluations from students.
  • Selective adsorption behavior of phosphate onto aluminum hydroxide gel, Naohito Kawasaki, Fumihiko Ogata, Hisato Tominaga, JOURNAL OF HAZARDOUS MATERIALS, JOURNAL OF HAZARDOUS MATERIALS, 181(1-3), 574 - 579, Sep. 2010 , Refereed
    Summary:The specific surface area and X-ray diffraction patterns for an aluminum hydroxide gel (AHG) calcined at 300-1150 degrees C, the number of surface hydroxyl groups in the AHG, and the adsorption isotherms of phosphate on AHG were measured in order to develop a phosphate recovery agent. AHG was transformed into gamma- and alpha-alumina by the calcinations treatment. The amount of phosphate adsorbed onto AHG increases at calcining temperatures of 300-700 degrees C and decreases above a calcining temperature of 800 degrees C. It was found that AHG selectively adsorbs phosphate ions, but not other anions, and shows the highest adsorption capacity at pH 4-6. Further, the alkali resistance of AHG increased with calcination, and more than 80% of the phosphate adsorbed with an NaOH aqueous solution underwent desorption. The addition of colloidal alumina and colloidal silica resulted in the formation of granules of 500-840 mu m size. The amount of phosphate adsorbed onto AHG after granulation was similar to that before granulation. Thus, the phosphate absorption capacity of AHG did not decrease after granulation suggesting that AHG can be used as a phosphate adsorbent. Published by Elsevier B.V.
  • Removal of cadmium and copper by vegetable biomass treated with hydrochloric acid, Naohito Kawasaki, Hisato Tominaga, Fumihiko Ogata, Kazuaki Kakehi, CHEMICAL ENGINEERING JOURNAL, CHEMICAL ENGINEERING JOURNAL, 157(1), 249 - 253, Feb. 2010
    Summary:Food waste is discharged abundantly, and while some of it is reused, most is incinerated. The recycling of soybean waste and wheat bran as vegetable biomass needs to become established, and the ability to remove Cd(2+) and Cu(2+) by vegetable biomass needs to be estimated. The estimations performed here revealed that the amounts of Cd(2+) and Cu(2+) adsorbed onto untreated vegetable biomass were larger than those adsorbed onto defatted biomass. This indicates that the adsorption of Cd(2+) and Cu(2+) onto vegetable biomass may depend on fat content. On the other hand, the elution percentage of vegetable biomass increased as the concentration of hydrochloric acid increased. The elution is due to the degradation of protein in the biomass by the acid. The amounts of Cd(2+) and Cu(2+) adsorbed decreased as more than 0.10 mol/L of the concentration of hydrochloric acid increased. Cd(2+) and Cu(2+) are adsorbed on vegetable biomass by their adsorption onto protein. The amounts of Cu(2+) adsorbed onto soybean waste and wheat bran in a binary-solution system are larger than those in a single-solution system. However, less Cd(2+) was adsorbed onto wheat bran in the binary system than in the single one. These results indicated that the amount of Cu(2+) adsorbed increases in the presence of Cd(2+). Either the adsorption of Cd(2+) onto wheat bran is inhibited by Cu(2+) or the adsorptions of Cd(2+) and Cu(2+) onto the biomass were affected by each other. (C) 2009 Elsevier B. V. All rights reserved.
  • Removal of Fluoride Ion by Bone Char Produced from Animal Biomass, Naohito Kawasaki, Fumihiko Ogata, Hisato Tominaga, Isao Yamaguchi, JOURNAL OF OLEO SCIENCE, JOURNAL OF OLEO SCIENCE, 58(10), 529 - 535, Oct. 2009 , Refereed
    Summary:Bone char (BC) was prepared by carbonizing four types of animal biomass, and the adsorption of fluoride ions and elution of phosphate ions were investigated. It was found that the BC yield decreased as carbonization temperature increased, and that carbonization temperature had no significant effect on surface pH, base or acid consumptions. Fluoride ion adsorption was increased in BC produced at a low carbonization temperature. The adsorption mechanism of fluoride ion on BCs might be monolayer adsorption. BC can potentially be used to remove fluoride ions in drinking water. However, it was found that phosphate ions from BC are eluted due to adsorption of fluoride ions, and that ingestion of large amounts of phosphate ions inhibits reabsorption of calcium in the human body. Thus there is a need to study the elution behavior of phosphate ions. The adsorption mechanisms of fluoride ions onto BC would be a physical adsorption onto BC and phosphate ion in BC is exchanged to fluoride ion.
  • Survey of Relationship between Measurement of Abdominal Circumference and Metabolic Syndrome on New Health Check in University, Naohito Kawasaki, Tadao Takashima, Kazunori Sagawa, Hidekazu Yamada, Katsuhisa Shindo, Kazuaki Kakehi, YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 129(8), 965 - 974, Aug. 2009 , Refereed
    Summary:In April 2008, a system of special health checks and health guidance was initiated with the aim of identifying people with metabolic syndrome (visceral fat syndrome) and pre-metabolic syndrome. In this study, we investigated the relationship between health check results and abdominal circumference in 632 university faculty members. The standard value for abdominal circumference in women (>= 90) is set higher than that for men (>= 85). When this standard value is used, only 7.4% of women may be able to receive special health guidance. In the future, a follow-up survey of female subjects focusing on the difference in the standard value and an evaluation of its relationship with lifestyle-related diseases will probably be necessary. In the present study, significant positive correlations were seen between abdominal circumference and GPT and gamma-GTP, which are related to hepatic function, and between abdominal circumference and uric acid levels in mates. These results indicate the possibility that abdominal circumference is related to alcohol intake. In addition, white blood cell count, red blood cell count, hemoglobin level, and hematocrit level were significantly higher in subjects with large abdominal circumference, and there were differences in hematopoietic function. There have been virtually no studies on the relationship between visceral fat and hepatic and hematopoietic functions, and a follow-up study of the present subjects in the future may shed new light on risk factors for various diseases with abdominal circumference as an indicator.
  • Degradation Characteristics of 17 beta-Estradiol by Ozone Treatment with Activated Carbon, Naohito Kawasaki, Fumihiko Ogata, Isao Yamaguchi, Hisato Tominaga, JOURNAL OF OLEO SCIENCE, JOURNAL OF OLEO SCIENCE, 58(5), 261 - 266, May 2009 , Refereed
    Summary:The present study investigates (1) ozone treatment, (2) adsorption treatment using activated carbon treatment, and (3) ozone treatment with activated carbon for their efficacy in removing 17 beta-estradiol (E2) present in an aqueous solution. Both ozone and activated carbon treatments for 20 min were effective in removing E2 (initial concentration, 100 mg/L). However, both treatments have been used for two processes, and the disposal time with these treatments is more than that of another treatment. In this study, ozone treatment with activated carbon was investigated with regard to the percentage of E2 removal, pH, and chemical oxygen demand (COD). The physical and chemical characteristics of the activated carbon surface were modified due to the ozone treatment: the surface was oxidized by ozone. The surface of activated carbon exhibited polarity groups and became porous after ozone treatment. The amount of E2 adsorbed onto the ozone-treated activated carbon surface was similar to that adsorbed onto the untreated activated carbon surface. The percentage of E2 removal by ozone treatment with activated carbon was greater than that by ozone treatment alone. Moreover, the rate of E2 removal by ozone treatment with activated carbon was higher than that by ozone or activated carbon treatments alone. Ozone with activated carbon treatment may be used for the removal of E2. However, this ozone treatment for the degradation of E2 may have a greater COD than that in the case of activated carbon treatment alone.
  • Adsorption Properties of As(III) and Cr(VI) in Water Environment by Calcined Gibbsite, Fumihiko Ogata, Naohito Kawasaki, Mineaki Kabayama, Kazuaki Kakehi, CHEMICAL & PHARMACEUTICAL BULLETIN, CHEMICAL & PHARMACEUTICAL BULLETIN, 57(2), 129 - 133, Feb. 2009 , Refereed
    Summary:The adsorption properties of As(III) and Cr(VI) by gibbsite (GB) calcined at 200 to 1150 degrees C was investigated on basis of their specific surface area, number of hydroxyl groups, surface pH and adsorption isotherms. The amount of As(III) and Cr(VI) adsorbed on the calcined GB at 300 or 400 degrees C was the highest. In the case of the calcination temperature was more than 700 degrees C, the amount adsorbed decreased with the increasing calcination temperature. In a single solution system, the amount of As(III) adsorbed on calcined GB was higher than that of Cr(VI). The amount of As(III) and Cr(VI) adsorbed on calcined GB was higher in a binary solution system than those in a single solution system. The pH in solution after As(III) and Cr(VI) adsorption was greater than that before adsorption. These results indicated that the adsorption mechanism of As(III) and Cr(VI) was as followed: the hydroxyl groups on calcined GB were exchanged to As(III) and Cr(VI) and they adsorbed n the calcined GB surface. In the case of coexistence of As(III) and Cr(VI), they could be removed better by calcined GB because the pH in binary solution was lower than that in single solution. Both As(III) and Cr(VI) in water environment could be removed by the calcined GB simultaneously.
  • Removal of Orange II, Methylene Blue and Humic Acid by Ozone-Activated Carbon Combination (OZAC) Treatment, Naohito Kawasaki, Fumihiko Ogata, Isao Yamaguchi, Atsushi Fujii, JOURNAL OF OLEO SCIENCE, JOURNAL OF OLEO SCIENCE, 57(7), 391 - 396, Jul. 2008 , Refereed
    Summary:To prevent formation of trihalomethanes (THMs) in drinking water, removing precursors of trihalomethanes (PTHMs) in water resources for tap water is essential. We compared the following three treatments for removal of PTHMs: activated carbon (AC), ozone (OZ) and ozone-activated carbon combination (OZAC). Orange II (OR, an acidic dye), methylene blue (MB, a basic dye) and humic acid (HA) were used as PTHMs. HA exists abundantly as PTHM in nature. Results demonstrated that PTHMs could be decomposed or removed by either AC or OZ treatment. Efficiency of removal of HA by the three treatment methods was lower than that for removal of OR and MB, as the molecules of HA were larger than those of OR and MB. Decreases of total organic carbon values were achieved by treatment of MB with OZ or HA with AC. As for advanced water treatment, a two-step sequential process of OZ-AC treatments is currently used. However, the present results demonstrated that highly efficient removal of PTHMs could be accomplished by the addition of AC during OZ treatment.
  • Effects of essential medicines on cardiovascular products available for the market in Thailand, Siriporn Burapadaja, Naohito Kawasaki, Suporn Charumanee, Fumihiko Ogata, HEALTH POLICY, HEALTH POLICY, 84(1), 67 - 74, Nov. 2007 , Refereed
    Summary:National List of Essential Medicines (NLEM) is an important policy on drugs, which also covers the drug availability. However, the link between the list and the availability of medicine products for the market is not clear. The objectives of this study were to examine the effects of essential medicines (EM) on the patterns and values of cardiovascular products available for the market in Thailand. Issues investigated were proportions of products, expansions of generic names, involvement of producers and relation between the numbers of EM generic names and production values of products. Data sources were NLEM, Thailand Index of Medical Specialities and drug statistics by Food and Drug Administration (FDA). Results revealed the availability of 623 products from 127 generic names. On average, EM products showed significantly greater proportions and EM generic names demonstrated larger expansions than non-EM. Domestic producers contributed to List A products by a significantly higher percentage than foreign, but only foreign producers introduced List D products. There was a positive and significant relation between the numbers of EM generic names and the production values of products. In conclusion, it was clear that EM had effects on the patterns and the values of cardiovascular products available for the market. Subsequent prices and expenditure due to the patterns and values of product availability could be low or high. These findings could be advantageous in using essential medicines as a means to avoid the negative consequences by addressing the significance of its kinds and numbers when selecting it in the list. (c) 2007 Published by Elsevier Ireland Ltd.
  • Study on variations in price of prescription medicines in Thailand, Siriporn Burapadaja, Naohito Kawasaki, Ornanong Kittipongpatana, Fumihiko Ogata, YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 127(3), 515 - 526, 2007 , Refereed
    Summary:There are evidences describing that the prices of prescription medicines can affect users, suppliers, and, in particular, payers in the health care system. Despite the significant effects of prices, the information regarding their characteristics is scarce. The objective of this study was to examine the prices and price variations of prescription medicines in an actual setting. A cross-sectional study on the prices of prescription medicines listed in a hospital formulary was undertaken. The medicines (n = 1531) listed in the formulary were recorded according to the category of the medicine (essential or non-essential medicines), manufacturer types (local or foreign), dosage forms, therapeutic classifications (classes), and prices per unit in Baht. This study used coefficients of relative variations (CRVs) to determine the extent of price variations. Results revealed that the mean prices of non-essential and foreign medicines were significantly greater than those of its counterparts by 1.7 and 21.2 times, respectively. On an average, the classes with the highest prices were blood-related, antineoplastic, and endocrinological agents, while those with the lowest prices were the psychotherapeutic, CNS, and cardiovascular agents. The majority of the medicines (37%) were in the price range of >10-100 Baht. The price variations of different classes of medicines varied from about 100% to 600%. The mean price and CRV levels (low and high) formed four groups of medicines with different risks of high prices and variations to payers. In conclusion, the prices are associated with the category and manufacturer type. The prices and their variations could be used to distinguish the classes of medicines that possess different risks of high prices and variations to payers. Identifying the classes with high prices and high variations, high prices and low variations, and low prices and high variations is necessary for careful intervention to reduce the effect of prices and their variations on payers.
  • Removal of arsenious ion by calcined aluminum oxyhydroxide (boehmite), Fumihiko Ogata, Naohito Kawasaki, Takeo Nakamura, Seiki Tanada, JOURNAL OF COLLOID AND INTERFACE SCIENCE, JOURNAL OF COLLOID AND INTERFACE SCIENCE, 300(1), 88 - 93, Aug. 2006 , Refereed
    Summary:Aluminum oxyhydroxide (boehmite, BE) shows adsorption ability of arsenious ion. In this study, we calcined BE in the temperature range 200-1150 degrees C, and examined the amount of arsenious ion adsorbed and adsorption mechanism. As a result, the adsorption amount of arsenious ion by BE calcined at 400 degrees C showed the highest value as compared with those by BE calcined at other temperatures. On the other hand, the amounts of arsenious ion adsorbed onto BE showed lower values at 200, 600, and > 1000 degrees C than that by BE before calcination. The amount of surface hydroxyl group of calcined BE showed the highest value at the calcination temperature of 400 degrees C. As a result of X-ray analysis, BE showed boehmite structure at less than the calcination temperature of 300 degrees C, while BE was converted to the transitional state of aluminum oxide at more than 400 degrees C. From the result of the amount of arsenious ion adsorbed and FT-IR, it turned out that calcined BE dissociated water molecule when suspended in the water, hydroxyl group was generated on the surface, and the amount of arsenious ion adsorbed was increased because of the ion exchange of these hydroxyl groups with arsenious ions. It was clarified that an adsorbent with high adsorption ability of arsenious ion was obtained by calcination of BE. (c) 2006 Elsevier Inc. All rights reserved.
  • Removal of lead ions in drinking water by coffee grounds as vegetable biomass, T Tokimoto, N Kawasaki, T Nakamura, J Akutagawa, S Tanada, JOURNAL OF COLLOID AND INTERFACE SCIENCE, JOURNAL OF COLLOID AND INTERFACE SCIENCE, 281(1), 56 - 61, Jan. 2005
    Summary:In an attempt to reuse food waste for useful purposes, we investigated the possibility of using coffee grounds to remove lead ions from drinking water. We studied the lead ion adsorption characteristics of coffee beans and grounds by measuring their fat and protein content, adsorption isotherms for lead ions, and adsorption rates for lead ions. The number of lead ions adsorbed by coffee grounds did not depend on the kind of coffee beans or the temperature at which adsorption tests were performed. The rate of lead ion adsorption by coffee grounds was directly proportional to the amount of coffee grounds added to the solution. When coffee grounds were degreased or boiled, the number of lead ions decreased. When proteins contained in coffee grounds were denatured, the lead ion adsorption was considerably reduced. The lead ion adsorption capacity of coffee grounds decreased with increased concentration of perchloric acid used for treating them and disappeared with 10% perchloric acid. The experiments demonstrated that proteins contained in coffee beans depend upon the adsorption of lead ion. The present study gave an affirmative answer to the possibility Of using, coffee grounds, an abundant food waste, for removing lead ions from drinking water. (C) 2004 Elsevier Inc. All rights reserved.
  • Study on adsorption kinetic of aromatic hydrocarbons onto activated carbon in gaseous flow method, N Kawasaki, H Kinoshita, T Oue, T Nakamura, S Tanada, JOURNAL OF COLLOID AND INTERFACE SCIENCE, JOURNAL OF COLLOID AND INTERFACE SCIENCE, 275(1), 40 - 43, Jul. 2004 , Refereed
    Summary:The adsorption behavior of benzene, toluene, o-xylene, m-xylene, and p-xylene onto activated carbon was investigated using the flow method. The removal efficiency of aromatic hydrocarbons in the gaseous phase was estimated based on the adsorption kinetic constants and the saturated amount of aromatic hydrocarbons adsorbed on the activated carbon. The saturated amount of benzene and toluene adsorbed was greater than that of xylene adsorbed because the molecular sizes of benzene and toluene are smaller than that of xylene. The adsorption kinetic constant increased in the order of xylene, toluene, and benzene. Those of the three xylene isomers were similar. These results indicated that the adsorption rate of benzene by the activated carbon was the fastest and the kinetic constant depended upon the different between the boiling point and the melting point and the molecular size of the aromatic hydrocarbons. (C) 2004 Elsevier Inc. All rights reserved.
  • Study on adsorption kinetic of aromatic hydrocarbons onto activated carbon in gaseous flow method, N Kawasaki, H Kinoshita, T Oue, T Nakamura, S Tanada, JOURNAL OF COLLOID AND INTERFACE SCIENCE, JOURNAL OF COLLOID AND INTERFACE SCIENCE, 275(1), 40 - 43, Jul. 2004
    Summary:The adsorption behavior of benzene, toluene, o-xylene, m-xylene, and p-xylene onto activated carbon was investigated using the flow method. The removal efficiency of aromatic hydrocarbons in the gaseous phase was estimated based on the adsorption kinetic constants and the saturated amount of aromatic hydrocarbons adsorbed on the activated carbon. The saturated amount of benzene and toluene adsorbed was greater than that of xylene adsorbed because the molecular sizes of benzene and toluene are smaller than that of xylene. The adsorption kinetic constant increased in the order of xylene, toluene, and benzene. Those of the three xylene isomers were similar. These results indicated that the adsorption rate of benzene by the activated carbon was the fastest and the kinetic constant depended upon the different between the boiling point and the melting point and the molecular size of the aromatic hydrocarbons. (C) 2004 Elsevier Inc. All rights reserved.
  • Decolorization of indigo carmine by charcoal from extracted residue of coffee beans, T Nakamura, M Hirata, N Kawasaki, S Tanada, T Tamura, Y Nakahori, JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART A-TOXIC/HAZARDOUS SUBSTANCES & ENVIRONMENTAL ENGINEERING, JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART A-TOXIC/HAZARDOUS SUBSTANCES & ENVIRONMENTAL ENGINEERING, 38(3), 555 - 562, 2003 , Refereed
    Summary:The adsorption ability of charcoal from extracted-residue of coffee beans for indigo carmine removal was investigated by the batch-method. Differences in the removal ratio and removal rate of, indigo carmine could be explained by differences in the properties of charcoal. In the relationship between the amount of indigo carmine adsorbed and the square root of elapsed time, a good linearity was recognized. Since the relationship between the amount of indigo carmine adsorbed and square root of elapsed time showed a good linearity, the intraparticle diffusion of indigo carmine onto pores of adsorbents was identified as the rate-limiting step in the adsorption process.
  • Characterization of water adsorption onto carbonaceous materials produced from food wastes, A Nakanishi, M Tamai, N Kawasaki, T Nakamura, M Araki, S Tanada, JOURNAL OF COLLOID AND INTERFACE SCIENCE, JOURNAL OF COLLOID AND INTERFACE SCIENCE, 255(1), 59 - 63, Nov. 2002 , Refereed
    Summary:The recycling of organic wastes has become very important and the development of technology for recycling organic wastes needs to sustain industrial development. In this study, techniques for producing carbonaceous materials from organic wastes are described and water adsorption is characterized. The organic wastes used are coffee grounds and oolong tea leaves carbonized at 673 to 1073 K. The iodine adsorption capacity of the carbonaceous materials increased with increased carbonization temperature. The amount of water adsorbed onto the carbonization materials produced from oolong tea leaves at 873 K for 2 h was the highest. The Freundlich constant 1/n and the differential heat of adsorption of the carbonaceous materials produced from oolong tea leaves were greater than that of the carbonaceous materials produced from coffee grounds. The ability to humidity control can be estimated by the difference between the amount of water adsorbed relative pressure 0.90 and that at relative pressure 0.55. The ability to humidity control was the greatest for the carbonaceous materials produced from the oolong tea leaves at 873 K for 2 h and did not depend upon the adsorption temperature. These results indicated that the carbonaceous materials produced from oolong tea leaves at 873 K for 2 h could have more humidity control. (C) 2002 Elsevier Science (USA).
  • Inhibitory effect of sorbitol on acetaminophen adsorption by activated carbon, T Nakamura, Y Oida, K Matsumoto, N Kawasaki, S Tanada, JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART A-TOXIC/HAZARDOUS SUBSTANCES & ENVIRONMENTAL ENGINEERING, JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART A-TOXIC/HAZARDOUS SUBSTANCES & ENVIRONMENTAL ENGINEERING, 37(5), 905 - 912, 2002 , Refereed
    Summary:The effective use of activated carbon as oral adsorbent in the primary treatment of acute acetaminophen poisoning was studied. The adsorption characteristics of acetaminophen onto activated carbons in presence of sorbitol were investigated in vitro. Both the equilibrium amount adsorbed and the removal rate of acetaminophen onto activated carbon were decreased with the increase of sorbitol concentration in solutions. The sorbitol concentration independency of the inhibition to the acetaminophen adsorption was recognized. It was concluded that the addition of sorbitol to the suspension of activated carbon inhibited the acetaminophen adsorption by activated carbon.
  • MOISTURE SORPTION CHARACTERISTICS OF STEER HIDE COLLAGEN-FIBERS TREATED WITH CALCIUM HYDROXIDE, K BOKI, N KAWASAKI, FOOD HYDROCOLLOIDS, FOOD HYDROCOLLOIDS, 379 - 382, 1993 , Refereed

Conference Activities & Talks

  • Recovery of Phosphate by Dried Aluminum Hydroxide Gel, The 13th Asia Pacific Confederation of Chemical Engineering Congress,   2010 10 , The 13th Asia Pacific Confederation of Chemical Engineering Congress
  • Removal of Fluoride Ion by New Carbonaceous Materials in Aqueous Phase, 39th International Conference on Coordination Chemistry,   2010 07 , 39th International Conference on Coordination Chemistry
  • Formation of trihalomethanes from dyes by ozone treatment,   2009 08
  • Ozone-Activated carbon combination treatment of precursors of trihalomethanes,   2008 11
  • Removal of Fluoride Ion by Bone Char Produced from Animal Biomass,   2008 08
  • Production of Carbonaceous Materials from Waste Fibre,   2008 08
  • Recovery of phosphate from sea water using boehmite with sulfate group,   2007 12
  • Adsorption Mechanism of Arsenic and Chromium onto Calcined Gibbsite,   2007 12
  • Removal of heavy metal ions by vegetable biomass,   2006 08
  • Removal of arsenious ion by calcined boehmite in drinking water,   2006 08
  • Effective removal of diquat by activated carbon, The 4th International Congress of Asian Society of Toxicology,   2006 06 , The 4th International Congress of Asian Society of Toxicology
  • Production of Adsorbents from Soybean Residue for Humic Acid Removal, Biomass-Asia Form,   2006 01 , Biomass-Asia Form
  • Removal of arsenious acid by calcined boehmite in drinking water,   2005 11
  • Adsorption behavior of phosphate aluminum compounds for preventing eutrophication,   2005 11
  • Recycle technology of coffee grounds as vegetable biomass for preventing of global warming, 8th International Global Atomospheric Chemistry Conference,   2005 09 , 8th International Global Atomospheric Chemistry Conference
  • Hydrogen sulfide removal by iron and zinc containing activated carbon, The 16th Rgional Conference of Clean Air and Environment in Asia Pacifc Area,   2005 08 , The 16th Rgional Conference of Clean Air and Environment in Asia Pacifc Area
  • Development of water treatment technology by vegetable biomass,   2005 01
  • Recycling use of food waste, the lees of YUZU(Citrus junos), as an adsorbent for dye,   2004 10
  • Adsorption properties of CFC onto plasma-treated activated carbon,   2004 01
  • Removal of noneylphenol by carbonous materials produced from cottonseed shell,   2001 03

Works

  • Ozone and Activated Carbon Treatment of Endocrine Disruptors
  • Studies on Carbon Circulation and Recycling by Carbonization of Organic By-Products

Misc

  • Basic study of relationships between androgenetic alopecia and some lifestyle habits, like stress, 渡邉尚子, 岡村勝正, 山田秀和, 山田秀和, 緒方文彦, 川崎直人, 川崎直人, Fragrance Journal, 47, 10, 27‐33, 33,   2019 10 15 , https://jglobal.jst.go.jp/detail?JGLOBAL_ID=201902258919453430
  • ココヤシファイバーによるメチレンブルー除去, 植松勇伍, 緒方文彦, 中村武浩, 山城海渡, 川崎直人, 川崎直人, 日本公衆衛生学会総会抄録集, 78th, 580,   2019 10 10 , https://jglobal.jst.go.jp/detail?JGLOBAL_ID=201902242705793565
  • 大学生における睡眠と生活習慣および身体的・精神的健康状態との関連性, 山城海渡, 緒方文彦, 中村武浩, 植松勇伍, 川崎直人, 川崎直人, 日本公衆衛生学会総会抄録集, 78th, 222,   2019 10 10 , https://jglobal.jst.go.jp/detail?JGLOBAL_ID=201902244614063005
  • 特定健診における腹囲と血液検査結果との関連性, 川崎直人, 川崎直人, 山城海渡, 緒方文彦, 中村武浩, 多根井重晴, 日本公衆衛生学会総会抄録集, 78th, 338,   2019 10 10 , https://jglobal.jst.go.jp/detail?JGLOBAL_ID=201902266951062131
  • 女性における脱毛症と加齢,生活習慣および毛髪中ミネラル濃度との関連性, 中村武浩, 山城海渡, 緒方文彦, 川崎直人, 日本公衆衛生学会総会抄録集, 78th, 429,   2019 10 10 , https://jglobal.jst.go.jp/detail?JGLOBAL_ID=201902270352184192
  • 廃繊維由来炭素材料の創製とオゾンによる実排水処理, 川崎直人, 緒方文彦, 中村武浩, 日本オゾン協会年次研究講演会講演集, 28th, 155,   2019 06 20 , https://jglobal.jst.go.jp/detail?JGLOBAL_ID=201902213421496704
  • ニッケルおよびコバルトを基材とした金属複合水酸化物による水質浄化効果および細胞毒性に関する基礎研究, 緒方文彦, 中村武浩, 中島誠隆, 川崎直人, Journal of Toxicological Sciences, 44, Supplement, S283, S283,   2019 06 , https://jglobal.jst.go.jp/detail?JGLOBAL_ID=201902270060039428
  • コーヒー豆かすによる飲料水中の鉛イオンの除去能の評価と吸着制御因子の解明, 山城海渡, 緒方文彦, 中村武浩, 川崎直人, 川崎直人, Journal of Toxicological Sciences, 44, Supplement, S238, S238,   2019 06 , https://jglobal.jst.go.jp/detail?JGLOBAL_ID=201902298235471832
  • 流通法による活性白土を用いた導電率の低減に関する検討, 永橋瑛梨, 岩城宇亮, 岩城宇亮, 緒方文彦, 中村武浩, 川崎直人, 日本薬学会年会要旨集(CD-ROM), 139th, 3, ROMBUNNO.21PO‐pm248, 219,   2019 03 , https://jglobal.jst.go.jp/detail?JGLOBAL_ID=201902253131760415
  • 健康障害防止のための変敗食用油における脂肪酸組成の改善, 緒方文彦, 阿美はるか, 中村武浩, 川崎直人, 日本薬学会年会要旨集(CD-ROM), 139th, 3, ROMBUNNO.21PO‐pm219, 215,   2019 03 , https://jglobal.jst.go.jp/detail?JGLOBAL_ID=201902256796822580
  • 大学生の朝食欠食や睡眠状況と身体的及び精神的健康指標との関連性, 川崎直人, 川崎直人, 佐川和則, 佐川和則, 緒方文彦, 山城海渡, 中村武浩, 日本薬学会年会要旨集(CD-ROM), 139th, 3, ROMBUNNO.21PO‐am244, 200,   2019 03 , https://jglobal.jst.go.jp/detail?JGLOBAL_ID=201902274139149951
  • 活性白土による網羅的な陽イオン吸着による導電率の低減, 永橋瑛梨, 緒方文彦, 中村武浩, 川崎直人, 岩城宇亮, 岩城宇亮, 日本水環境学会年会講演集, 53rd, 57,   2019 03 01 , https://jglobal.jst.go.jp/detail?JGLOBAL_ID=201902211870025866
  • フライアッシュから創製した新規Na型とK型ゼオライトへの水銀および鉛の除去能, 小林悠平, 緒方文彦, 中村武浩, 川崎直人, 日本水環境学会年会講演集, 53rd, 59,   2019 03 01 , https://jglobal.jst.go.jp/detail?JGLOBAL_ID=201902282712317371
  • 水質改善を指向したFe‐Mg型ハイドロタルサイトとリン酸イオンとの相互作用に関する基礎研究, 緒方文彦, 岸田真央, 中村武浩, 川崎直人, 日本水環境学会年会講演集, 53rd, 241,   2019 03 01 , https://jglobal.jst.go.jp/detail?JGLOBAL_ID=201902284393541688
  • 男性における毛髪中の金属濃度と生活習慣及び数種の疾病との関連性, 川崎直人, 川崎直人, 山城海渡, 緒方文彦, 中村武浩, Fundamental Toxicological Sciences (Web), 5, Supplement, 122,   2018 11 12 , http://jglobal.jst.go.jp/public/201902249888912129
  • 毛髪中の金属濃度測定による骨粗しょう症の予測に関する研究, 山城海渡, 緒方文彦, 中村武浩, 川崎直人, 川崎直人, Fundamental Toxicological Sciences (Web), 5, Supplement, 96,   2018 11 12 , http://jglobal.jst.go.jp/public/201902251318581767
  • 粘土鉱物による網羅的イオンの吸着による伝導度の低減, 永橋瑛梨, 岩城宇亮, 緒方文彦, 中村武浩, 川崎直人, 日本吸着学会研究発表会講演要旨集, 32nd, 68,   2018 11 08 , http://jglobal.jst.go.jp/public/201902239127930274
  • フライアッシュ由来新規K型ゼオライトの創製とPb2+吸着能, 小林悠平, 緒方文彦, 中村武浩, 川崎直人, 日本吸着学会研究発表会講演要旨集, 32nd, 67,   2018 11 08 , http://jglobal.jst.go.jp/public/201902263594600023
  • 新規院内製剤セレン含有口腔内崩壊錠の作製と実用化についての検討, 中尾元紀, 松尾世為子, 大橋香菜子, 田邨保之, 永井聡子, 覺野律, 中村明美, 福永聖子, 川端成佐, 寺倉智子, 松野純男, 緒方文彦, 川崎直人, 大竹裕子, 長井紀章, 国立病院総合医学会(Web), 72nd, ROMBUNNO.O‐19‐4 (WEB ONLY), 656,   2018 11 , http://jglobal.jst.go.jp/public/201902227131229724
  • 日本およびタイの大学生における理想体型と疲労・ストレスに関する調査研究, 山城海渡, 多根井重晴, BURAPADAJA Siriporn, 緒方文彦, 川崎直人, 川崎直人, 日本公衆衛生学会総会抄録集, 77th, 581, 581,   2018 10 09 , http://jglobal.jst.go.jp/public/201802219784041658
  • 日本およびタイの薬学部生における食習慣と運動習慣に関する調査研究, 川崎直人, 川崎直人, 山城海渡, 緒方文彦, 多根井重晴, BURAPADAJA Siriporn, 日本公衆衛生学会総会抄録集, 77th, 581, 581,   2018 10 09 , http://jglobal.jst.go.jp/public/201802269189273196
  • 新規ニッケル‐アルミニウム系ハイブリッド型吸着剤によるホウ酸イオンの吸着挙動, 緒方文彦, 山城海渡, 川崎直人, 日本公衆衛生学会総会抄録集, 77th, 576,   2018 10 09 , http://jglobal.jst.go.jp/public/201802211543388425
  • 日本およびタイの大学生における理想体型と疲労・ストレスに関する調査研究, 山城 海渡, 多根井 重晴, Burapadaja Siriporn, 緒方 文彦, 川崎 直人, 日本公衆衛生学会総会抄録集, 77回, 581, 581,   2018 10
  • 日本およびタイの薬学部生における食習慣と運動習慣に関する調査研究, 川崎 直人, 山城 海渡, 緒方 文彦, 多根井 重晴, Burapadaja Siriporn, 日本公衆衛生学会総会抄録集, 77回, 581, 581,   2018 10
  • 新規Mg‐Fe‐Al金属複合体の創製およびそのリン吸着能, 長藤陸, 中村武浩, 小林悠平, 緒方文彦, 川崎直人, 衛生薬学・環境トキシコロジー講演要旨集, 2018, 197,   2018 08 23 , http://jglobal.jst.go.jp/public/201802220145215239
  • 有機系及び無機系材料を用いた環境水質の改善に関する研究, 永橋瑛梨, 緒方文彦, 中村武浩, 川崎直人, 衛生薬学・環境トキシコロジー講演要旨集, 2018, 193,   2018 08 23 , http://jglobal.jst.go.jp/public/201802240178634999
  • 植物バイオマスである小麦ふすまを用いた希少金属モリブデンの回収能に関する基礎研究, 緒方文彦, 笹野文, 中村武浩, 川崎直人, 衛生薬学・環境トキシコロジー講演要旨集, 2018, 185,   2018 08 23 , http://jglobal.jst.go.jp/public/201802256984994040
  • 毛髪中ミネラル濃度と花粉症,皮膚および脱毛との関連性, 川崎直人, 川崎直人, 山城海渡, 緒方文彦, 中村武浩, 衛生薬学・環境トキシコロジー講演要旨集, 2018, 247,   2018 08 23 , http://jglobal.jst.go.jp/public/201802273357485491
  • フライアッシュ由来新規ゼオライトの創製と鉛(II)イオンの吸着機構の解明, 小林悠平, 緒方文彦, 中村武浩, 川崎直人, 衛生薬学・環境トキシコロジー講演要旨集, 2018, 192,   2018 08 23 , http://jglobal.jst.go.jp/public/201802277334623728
  • 非侵襲的毛髪中ミネラル濃度の測定による生活習慣病の早期診断, 山城海渡, 緒方文彦, 中村武浩, 川崎直人, 川崎直人, 衛生薬学・環境トキシコロジー講演要旨集, 2018, 246,   2018 08 23 , http://jglobal.jst.go.jp/public/201802278744590200
  • バジルシードのハイドロコロイドはストロンチウムおよびセシウムイオン吸着に関与する, 植松勇伍, 緒方文彦, 中村武浩, 川崎直人, 衛生薬学・環境トキシコロジー講演要旨集, 2018, 165,   2018 08 23 , http://jglobal.jst.go.jp/public/201802287891532977
  • 男性型脱毛症(AGA)とヘモグロビン量またはストレスとの関連性に関する基礎研究, 川崎 直人, 渡邉 尚子, 岡村 勝正, 緒方 文彦, 山田 秀和, 日本抗加齢医学会総会プログラム・抄録集, 18回, 185, 185,   2018 05
  • ラロキシフェンを用いたナノ経皮吸収製剤の開発と骨粗鬆症治療への有用性評価, 出口 粧央里, 梁 宇紀, 大竹 裕子, 緒方 文彦, 川崎 直人, 長井 紀章, 日本薬剤学会年会講演要旨集, 33年会, 145, 145,   2018 05
  • 男性型脱毛症(AGA)とヘモグロビン量またはストレスとの関連性に関する基礎研究, 川崎直人, 川崎直人, 渡邉尚子, 岡村勝正, 緒方文彦, 山田秀和, 山田秀和, 日本抗加齢医学会総会プログラム・抄録集, 18th, 185, 185,   2018 05 , http://jglobal.jst.go.jp/public/201802250902913830
  • ラロキシフェンを用いたナノ経皮吸収製剤の開発と骨粗鬆症治療への有用性評価, 出口 粧央里, 梁 宇紀, 大竹 裕子, 緒方 文彦, 川崎 直人, 長井 紀章, 日本薬剤学会年会講演要旨集, 33年会, 145, 145,   2018 05
  • 環境水中における窒素およびリンの回収・除去技術の開発, 川崎直人, 緒方文彦, 中村武浩, 日本水環境学会年会講演集, 52nd, 55,   2018 03 09 , http://jglobal.jst.go.jp/public/201802216162746522
  • 水環境保全のためのリグニンによる亜鉛イオンの除去機構の解明, 永橋瑛梨, 緒方文彦, 中村武浩, 川崎直人, 日本水環境学会年会講演集, 52nd, 52,   2018 03 09 , http://jglobal.jst.go.jp/public/201802234466427068
  • オゾンおよび植物バイオマス由来炭素材料の併用処理による染料の分解能, 緒方文彦, 金原真子, 中村武浩, 川崎直人, 日本水環境学会年会講演集, 52nd, 488,   2018 03 09 , http://jglobal.jst.go.jp/public/201802264388560011
  • 創製したフライアッシュ由来ゼオライトを用いたPb2+およびHg2+の除去技術に関する研究, 小林悠平, 緒方文彦, 中村武浩, 川崎直人, 日本水環境学会年会講演集, 52nd, 51,   2018 03 09 , http://jglobal.jst.go.jp/public/201802268609759143
  • 新規炭化処理リグニンの創製およびその亜鉛イオン吸着能, 永橋 瑛梨, 緒方 文彦, 中村 武浩, 川崎 直人, 日本薬学会年会要旨集, 138年会, 3, 258, 258,   2018 03
  • 毛根を標的とした新規薬物送達技術の開発 ナノ結晶技術はミノキシジルの発毛効果を高める, 長井 紀章, 岩井 淑恵, 川瀬 七愛, 坂本 茜, 大竹 裕子, 緒方 文彦, 川崎 直人, 日本薬学会年会要旨集, 138年会, 4, 158, 158,   2018 03
  • フェントン反応を利用した難分解性有機化合物の分解・除去, 緒方 文彦, 中村 武浩, 川崎 直人, 日本薬学会年会要旨集, 138年会, 3, 231, 231,   2018 03
  • 血管内皮細胞の増殖を強力に促進する亜鉛錯体, 中村 武浩, 吉田 映子, 滝田 良, 緒方 文彦, 川崎 直人, 内山 真伸, 鍜冶 利幸, 日本薬学会年会要旨集, 138年会, 3, 249, 249,   2018 03
  • フライアッシュ由来新規ゼオライトの諸物性評価および有害重金属との相互作用, 小林 悠平, 緒方 文彦, 中村 武浩, 川崎 直人, 日本薬学会年会要旨集, 138年会, 3, 254, 254,   2018 03
  • フライアッシュ由来新規ゼオライトの諸物性評価および有害重金属との相互作用, 小林悠平, 緒方文彦, 中村武浩, 川崎直人, 日本薬学会年会要旨集(CD-ROM), 138th, 3, ROMBUNNO.26PA‐pm391, 254,   2018 03 , http://jglobal.jst.go.jp/public/201802246871292782
  • 血管内皮細胞の増殖を強力に促進する亜鉛錯体, 中村武浩, 中村武浩, 吉田映子, 滝田良, 緒方文彦, 川崎直人, 内山真伸, 鍜冶利幸, 日本薬学会年会要旨集(CD-ROM), 138th, 3, ROMBUNNO.26PA‐pm361, 249,   2018 03 , http://jglobal.jst.go.jp/public/201802269416137198
  • フェントン反応を利用した難分解性有機化合物の分解・除去, 緒方文彦, 中村武浩, 川崎直人, 日本薬学会年会要旨集(CD-ROM), 138th, 3, ROMBUNNO.26PA‐am380, 231,   2018 03 , http://jglobal.jst.go.jp/public/201802281099949818
  • 新規炭化処理リグニンの創製およびその亜鉛イオン吸着能, 永橋瑛梨, 緒方文彦, 中村武浩, 川崎直人, 日本薬学会年会要旨集(CD-ROM), 138th, 3, ROMBUNNO.26PA‐pm412, 258,   2018 03 , http://jglobal.jst.go.jp/public/201802282469742544
  • 毛根を標的とした新規薬物送達技術の開発:ナノ結晶技術はミノキシジルの発毛効果を高める, 長井紀章, 岩井淑恵, 川瀬七愛, 坂本茜, 大竹裕子, 緒方文彦, 川崎直人, 日本薬学会年会要旨集(CD-ROM), 138th, 4, ROMBUNNO.28PA‐pm142, 158,   2018 03 , http://jglobal.jst.go.jp/public/201802287421642773
  • 毛髪中のミネラル濃度の測定による健康指標への適用, 川崎直人, 川崎直人, 緒方文彦, 中村武浩, 日本公衆衛生学会総会抄録集, 76th, 282, 282,   2017 10 15 , http://jglobal.jst.go.jp/public/201702219917129643
  • フェノール性の天然高分子化合物による亜鉛の吸着能, 永橋瑛梨, 緒方文彦, 中村武浩, 小林悠平, 川崎直人, 衛生薬学・環境トキシコロジー講演要旨集, 2017, 203,   2017 08 18 , http://jglobal.jst.go.jp/public/201702211797450085
  • 見た目のアンチエイジングのための毛髪中ミネラル濃度の適用に関する研究, 山城海渡, 緒方文彦, 中村武浩, 川崎直人, 川崎直人, 衛生薬学・環境トキシコロジー講演要旨集, 2017, 316,   2017 08 18 , http://jglobal.jst.go.jp/public/201702247614682178
  • バジルシードによるストロンチウム及びセシウムイオンの吸着能, 植松勇伍, 緒方文彦, 中村武浩, 川崎直人, 衛生薬学・環境トキシコロジー講演要旨集, 2017, 192,   2017 08 18 , http://jglobal.jst.go.jp/public/201702250006121232
  • 新規Fe‐Mg型ハイドロタルサイトによるタングステンの吸着能, 緒方文彦, 川上真理奈, 中村武浩, 川崎直人, 衛生薬学・環境トキシコロジー講演要旨集, 2017, 164,   2017 08 18 , http://jglobal.jst.go.jp/public/201702261453120117
  • アルカリ水熱処理により創製したフライアッシュ由来ゼオライトへの鉛イオン吸着能, 小林悠平, 緒方文彦, 中村武浩, 永橋瑛梨, 川崎直人, 衛生薬学・環境トキシコロジー講演要旨集, 2017, 202,   2017 08 18 , http://jglobal.jst.go.jp/public/201702280406257351
  • 血管内皮細胞の増殖を強力に促進する亜鉛錯体, 中村武浩, 中村武浩, 吉田映子, 滝田良, 緒方文彦, 川崎直人, 内山真伸, 鍛冶利幸, 衛生薬学・環境トキシコロジー講演要旨集, 2017, 205,   2017 08 18 , http://jglobal.jst.go.jp/public/201702291778031095
  • The effect of NaCl concentration and permeability of medicines, administred using simple suspension method, by feeding tube, 緒方文彦, 林友典, 平田敦士, 能登啓介, 松岡寛, 川崎直人, 川崎直人, 臨床環境医学(Web), 26, 1, 45‐54 (WEB ONLY), 54,   2017 07 15 , http://jglobal.jst.go.jp/public/201702266324366191
    Summary:本研究では、簡易懸濁法実施時におけるNaClの影響およびチューブの通過性に関する基礎的検討を実施した。簡易懸濁法に使用する近畿大学医学部奈良病院内の水道水質調査を実施した結果、温湯および冷水ともにNa、Mg、Ca、B、Mn、Fe、Ni、Cu、Zn、Cd、およびBaの計11種が検出され、水道水質基準値を満たしていることが明らかとなった。アムロジピン、ファモチジンおよびメキシレチンを用いて薬剤主成分の溶出量を測定した結果、時間経過に伴い溶出量は増大する傾向が認められた。また、10%NaCl溶液を用いた場合、薬剤主成分の溶出量の低減が確認された。これらのことから、簡易懸濁法実施時におけるNaClの添加は、薬剤主成分の溶出量に影響をおよぼすことが明らかとなった(塩析現象)。さらに、懸濁薬剤のチューブ通過性に関する検討では、投与薬剤の全量を回収できることを明らかとした。(著者抄録)
  • 簡易懸濁法適応時におけるNaClの影響およびチューブ通過性に関する基礎的研究, 緒方 文彦, 林 友典, 平田 敦士, 能登 啓介, 松岡 寛, 川崎 直人, 臨床環境医学, 26, 1, 45, 54,   2017 07
    Summary:本研究では、簡易懸濁法実施時におけるNaClの影響およびチューブの通過性に関する基礎的検討を実施した。簡易懸濁法に使用する近畿大学医学部奈良病院内の水道水質調査を実施した結果、温湯および冷水ともにNa、Mg、Ca、B、Mn、Fe、Ni、Cu、Zn、Cd、およびBaの計11種が検出され、水道水質基準値を満たしていることが明らかとなった。アムロジピン、ファモチジンおよびメキシレチンを用いて薬剤主成分の溶出量を測定した結果、時間経過に伴い溶出量は増大する傾向が認められた。また、10%NaCl溶液を用いた場合、薬剤主成分の溶出量の低減が確認された。これらのことから、簡易懸濁法実施時におけるNaClの添加は、薬剤主成分の溶出量に影響をおよぼすことが明らかとなった(塩析現象)。さらに、懸濁薬剤のチューブ通過性に関する検討では、投与薬剤の全量を回収できることを明らかとした。(著者抄録)
  • 大学生の朝食欠食と身体的・精神的健康指標との関連性, 川崎 直人, 佐川 和則, 山田 秀和, 緒方 文彦, 日本抗加齢医学会総会プログラム・抄録集, 17回, 212, 212,   2017 06
  • 大学生の朝食欠食と身体的・精神的健康指標との関連性, 川崎直人, 川崎直人, 佐川和則, 佐川和則, 山田秀和, 山田秀和, 緒方文彦, 日本抗加齢医学会総会プログラム・抄録集, 17th, 212, 212,   2017 06 , http://jglobal.jst.go.jp/public/201702287381616906
  • ポリエチレンテレフタラートを用いたニッケル‐コバルト複合水酸化物の造粒およびそのリン酸イオン吸着能, 緒方文彦, 川崎直人, 戸田徳, 大谷昌司, 日本水環境学会年会講演集, 51st, 281,   2017 03 09 , http://jglobal.jst.go.jp/public/201702281046328312
  • 納豆による高血圧予防効果の解明 納豆菌酵素発酵代謝物は本態性高血圧の発症を抑制する, 長井 紀章, 真野 裕, 船上 仁範, 緒方 文彦, 伊藤 吉將, 後藤 和子, 川崎 直人, 日本薬学会年会要旨集, 137年会, 3, 204, 204,   2017 03
  • 簡易懸濁法適応時におけるNaClの影響およびチューブ通過性に関する基礎的研究, 緒方 文彦, 林 友典, 平田 敦士, 能登 啓介, 松岡 寛, 川崎 直人, 日本薬学会年会要旨集, 137年会, 3, 222, 222,   2017 03
  • 毛髪中の金属濃度測定による花粉症発症の予測に関する研究, 川崎 直人, 山城 海渡, 緒方 文彦, 日本薬学会年会要旨集, 137年会, 3, 228, 228,   2017 03
  • 簡易懸濁法適応時におけるNaClの影響およびチューブ通過性に関する基礎的研究, 緒方文彦, 林友典, 平田敦士, 能登啓介, 松岡寛, 川崎直人, 日本薬学会年会要旨集(CD-ROM), 137th, 3, ROMBUNNO.27PA‐pm003, 222,   2017 03 , http://jglobal.jst.go.jp/public/201702249516746720
  • 毛髪中の金属濃度測定による花粉症発症の予測に関する研究, 川崎直人, 川崎直人, 山城海渡, 緒方文彦, 日本薬学会年会要旨集(CD-ROM), 137th, 3, ROMBUNNO.27PA‐pm037, 228,   2017 03 , http://jglobal.jst.go.jp/public/201702269296438165
  • 納豆による高血圧予防効果の解明:納豆菌酵素発酵代謝物は本態性高血圧の発症を抑制する, 長井紀章, 真野裕, 船上仁範, 緒方文彦, 伊藤吉將, 後藤和子, 川崎直人, 日本薬学会年会要旨集(CD-ROM), 137th, 3, ROMBUNNO.26PB‐am120, 204,   2017 03 , http://jglobal.jst.go.jp/public/201702282312281858
  • Adsorption Capability of Cationic Dyes (Methylene Blue and Crystal Violet) onto Poly-gamma-glutamic Acid, Fumihiko Ogata, Noriaki Nagai, Naohito Kawasaki, CHEMICAL & PHARMACEUTICAL BULLETIN, 65, 3, 268, 275,   2017 03 , http://ci.nii.ac.jp/naid/130005397366
    Summary:In this study, the adsorption capability of cationic dyes, which were methylene blue and crystal violet, by poly-gamma-glutamic acid (PGA) in a single or binary solution system was investigated. The effect of the molecular weight of PGA, initial dye concentration, solution pH, and temperature on the adsorption of dyes was evaluated. The adsorption mechanism of dyes onto PGA was the interaction between -COOH group on the PGA surface and the polarity groups of dyes. These results indicated that PGA is useful for removal of dyes and cationic organic compounds from a single or binary solution system.
  • Development of the novel measurement method of intracellular metal ion in metallomics research, OGATA Fumihiko, SATOH Ryosuke, HAGIHARA Kanako, SUGIURA Reiko, KAWASAKI Naohito, Annual Meeting of the Japanese Society of Toxicology, 44, 0, P, 108,   2017 , http://ci.nii.ac.jp/naid/130006581970
    Summary:【目的】“メタロミクス”は,ゲノミクスおよびプロテオミクスと同様に,生体の機能解明のみならず,疾病や病態の理解においても重要な科学領域であると考えられる。特に,カルシウムや鉄イオンなどの金属イオンの細胞内挙動(細胞内濃度)を正確に把握することは,金属イオンを介した生体機能制御の分子メカニズムを解明するうえで重要である。本研究では,細胞内金属イオン濃度の定量時における条件の最適化を指向し,分裂酵母細胞を用いてICP-AES(OES)による細胞内金属イオン濃度の定量に関する基礎的検討を実施した。<br>【方法】分裂酵母<i>Schizosaccharomyces pombe</i>の野生細胞を用いて,細胞溶解条件の最適化(硝酸処理,zymolyase処理,westase処理)を行った。細胞溶解は微分干渉顕微鏡により評価した。次に,ICP-AESを用いて硝酸処理した野生細胞内のカルシウムイオン濃度を定量した。また,野生細胞および鉄イオントランスポーターであることが示唆されているPcl1のノックアウト(<i>pcl1</i> KO)細胞を用いて,ICP-OESにより細胞内鉄イオン濃度の定量も実施した。<br>【結果・考察】野生細胞を用いた細胞溶解条件の最適化の結果,60%の硝酸処理が最も適していることが明らかとなった。また,野生細胞内のカルシウムイオン濃度を定量した結果,細胞数依存的に濃度の増大が確認された。さらに,野生細胞および<i>pcl1</i> KO細胞内の鉄イオン濃度を比較した結果,<i>pcl1</i> KO細胞内の鉄イオン濃度の方が低いことが示され,先行研究<sup>1)</sup>と同様の結果が得られた。これらのことより,本研究で採用した細胞溶解条件は,酵母細胞内の金属イオンの定量に有効であることが示唆された。今後,各種金属イオンの同時定量法の確立や適用細胞の評価に関しても併せて検討を行う予定である。<br>【参考文献】<br><i>J. Biol. Chem.</i>, <b>287(51)</b>, 43042-43051.
  • Relationship between concentration of minerals in hair and disieases or life styles, KAWASAKI Naohito, OGATA Fumihiko, YAMASHIRO Kaito, Annual Meeting of the Japanese Society of Toxicology, 44, 0, O, 9,   2017 , http://ci.nii.ac.jp/naid/130006581945
    Summary:【目的】我が国では,健康増進や生活習慣病発症の予防を主な目的とし,食事摂取基準が策定されている。ミネラルは,多量ミネラル5種類と微量ミネラル8種類が対象となっている。生体中のミネラルの役割は多岐にわたっており,バランスよく摂取することが重要である。一方,毛髪は大部分がタンパク質であるケラチンから成り,ミネラルが排泄されるため,体内のミネラルの状態を正確に反映すると考えられている。本研究では,生活習慣病の予防などに関する知見を得ることを目的とし,ヒトの毛髪中におけるミネラル濃度を測定し,疾病や生活習慣に関するアンケート調査の結果との関連性について検討した。<br>【方法】本研究は近畿大学薬学部倫理委員会の承認に基づき実施された。内容を説明し,同意が得られた場合,同意書と生活習慣及び疾病に関するアンケートを記入後,毛髪を採取した。対象者は男性185名,女性398名であった。毛髪中ミネラル濃度は,前処理し,酸で溶解後,誘導結合プラズマ質量分析装置(島津ICPM-8500)を用いて定量した。毛髪中ミネラル濃度とアンケートとの関連性はJMP ver. 11(SAS Institute Inc.)により名義ロジスティック回帰分析を行い,有意水準は<i>p</i><0.05とした。<br>【結果・考察】血圧,血糖値,喫煙,肥満,運動及び脱毛の項目で「はい」と回答した男性の割合は,女性に比べて有意に高くなった。一方,貧血,骨密度,もの忘れ及び創傷治癒遅延の項目で「はい」と回答した男性の割合は,女性に比べて有意に低くなった。アンケート調査の結果と毛髪中のミネラル濃度と関連性とし,男性において,肥満の項目で「はい」と回答した人ほどセレン濃度が有意に低く,花粉症の項目で「はい」と回答した人ほどカドミウム濃度が有意に高くなった。一方,女性において,花粉症の項目で「はい」と回答した人ほどカルシウム濃度が有意に低くなった。以上の結果から,特定の毛髪中ミネラル濃度を定期的に測定することにより,健康への意識を向上させることにより,疾病予防に寄与できる可能性が示唆された。
  • Effect of Extract Containing Metabolic Products of Bacillus Subtilis Natto on Hypertension in SHR and SHR-SP Rats, Nagai Noriaki, Mano Yu, Funakami Yoshinori, Ogata Fumihiko, Ito Yoshimasa, Goto Kazuko, Kawasaki Naohito, Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences), 43, 2, 72, 79,   2017 , http://ci.nii.ac.jp/naid/130006342166
    Summary:<p>We investigated the preventive effect of extract containing metabolic products of <i>Bacillus subtilis natto</i> (NFE extract) on essential hypertension. The spontaneously hypertensive rat (SHR rat) and stroke-prone SHR rat (SHR-SP rat) were used in this study, and the NFE extract was administered by free drinking for 6-14 weeks of age (6, 7 weeks of age, 25 mL/day/rat; 8-14 weeks of age, 30 mL/day/rat). The administration of NFE extract did not affect the food intake and body weight in the WKY, SHR and SHR-SP rats. Significant changes in systolic (SBP) and diastolic (DBP) blood pressure levels between WKY rats administered with and without NFE extract were not observed for rats 6-14 weeks of age. On the other hand, the SBP and DBP in SHR and SHR-SP rats increased with aging, and the administration of NFE extract significantly attenuated the increased SBP, DBP in SHR and SHR-SP rats. In conclusion, the administration of NFE extract prevents increased blood pressure in SHR and SHR-SP rats. These findings provide significant information that can be used to design further studies aimed at elucidating the precise mechanism for decrease of blood pressure by NFE extract.</p>
  • Granulation of Cobalt-containing Nickel Hydroxide with Polyethylene Terephthalate and its Phosphate Ion Adsorption Capability, Ogata Fumihiko, Toda Megumu, Otani Masashi, Kawasaki Naohito, Journal of Water and Environment Technology, 15, 1, 22, 34,   2017 , http://ci.nii.ac.jp/naid/130005330431
    Summary:<p>In this study, nickel hydroxide containing cobalt as a co-precipitation hydroxide (NiCo91) was granulated with a binder (polyethylene terephthalate, PET) and characterized (scanning electron microscopy, specific surface area, amount of hydroxyl groups, and surface pH). In addition, the phosphate ion adsorption capability of the granulated adsorbent was evaluated by examining the effects of contact time and solution pH, analysis of adsorption isotherms, and a desorption study. It was confirmed that NiCo91 calcined at 270°C could be granulated using a PET binder. The specific surface area (32 m<sup>2</sup>/g) and hydroxyl group amount (0.19 mmol/g) of PET20S (20% binder content and < 500 μm particle diameter) were greater than those of other adsorbents. The amount of the adsorbed phosphate ions was greater for PET20S than that for other adsorbents, indicating that the adsorbent surface properties were related to the adsorption of phosphate ions. The phosphate ions adsorbed onto PET20S could be desorbed by different concentrations of sodium hydroxide, and at least three-fold increase in adsorption/desorption onto PET20S could be obtained. The results show that PET20S is highly promising as a renewable adsorbent of phosphate ions from aqueous solutions.</p>
  • ニッケル‐コバルト複合水酸化物によるリン酸イオン吸着能に関する基礎研究, 緒方文彦, 川崎直人, 戸田徳, 大谷昌司, 日本水環境学会シンポジウム講演集, 19th, 139‐140,   2016 09 13 , http://jglobal.jst.go.jp/public/201602290898611449
  • カチオン及びアニオン染料の除去能と活性白土の物理化学的性質との関連性, 植田絵里美, 緒方文彦, 川崎直人, 衛生薬学・環境トキシコロジー講演要旨集, 2016, 179,   2016 08 29 , http://jglobal.jst.go.jp/public/201602264117490086
  • 組成比の異なるMg/Feハイドロタルサイトによる3価ヒ素および6価クロムの吸着能に関する基礎研究, 緒方文彦, 植田絵里美, 川崎直人, 衛生薬学・環境トキシコロジー講演要旨集, 2016, 157,   2016 08 29 , http://jglobal.jst.go.jp/public/201602271245501939
  • 男性の毛髪中金属濃度と疾病・生活習慣との関連性, 川崎直人, 緒方文彦, 日本臨床環境医学会学術集会プログラム・抄録集, 25th, 55, 55,   2016 06 15 , http://jglobal.jst.go.jp/public/201702219268161855
  • 特定健診・特定保健指導による行動変容パターンと腹囲とメタボリックシンドロームとの関連性, 川崎直人, 川崎直人, 緒方文彦, 山田秀和, 山田秀和, 日本抗加齢医学会総会プログラム・抄録集, 16th, 195, 195,   2016 06 , http://jglobal.jst.go.jp/public/201602229959747843
  • 焼成処理した新規水酸化ニッケルの諸物性とそのリン酸イオン吸着能に関する基礎研究, 緒方文彦, 川崎直人, 戸田徳, 大谷昌司, 日本水環境学会年会講演集, 50th, 257,   2016 03 10 , http://jglobal.jst.go.jp/public/201602221213474913
  • カルシウム欠乏卵巣摘出ラットを用いた永久硬水および一時硬水の骨形成効果に関する基礎研究, 緒方文彦, 長井紀章, 伊藤吉將, 川崎直人, 日本薬学会年会要旨集(CD-ROM), 136th, 3, ROMBUNNO.29AB-AM380, 235,   2016 03 , http://jglobal.jst.go.jp/public/201602245568660411
  • 特定健康診査・保健指導による行動変容に関する追跡調査, 川崎直人, 緒方文彦, 松谷定, 日本薬学会年会要旨集(CD-ROM), 136th, 3, ROMBUNNO.29AB-AM393, 237,   2016 03 , http://jglobal.jst.go.jp/public/201602268706403905
  • Survey of life style disease and measurement of hair metal concentration in female, KAWASAKI Naohito, OGATA Fumihiko, Annual Meeting of the Japanese Society of Toxicology, 43, 0, O, 15,   2016 , http://ci.nii.ac.jp/naid/130005260573
    Summary:【目的】毛髪の構成成分の大部分は,酵素などにより分解されにくく,システイン含量が高いタンパク質であるケラチンである。一方,ミネラルは骨組織や電解質や酵素の成分として重要であり,体内に取り込まれた後,毛髪へも排泄される。したがって,毛髪中のミネラルを定期的に測定することにより,疾病に罹患する前に細胞レベルでの変動をみる検査に適用できる可能性がある。本研究では,毛髪中のミネラル濃度から疾病予防に関する有益な知見を得るため,疾病や生活習慣などに関するアンケート調査を行い,それらの結果と毛髪中の有害ミネラルおよび必須ミネラル濃度との関連性について検討した。<br>【方法】本研究は近畿大学薬学部倫理委員会の承認に基づき,同意が得られた20~50歳代の女性605名から後頭部より毛髪を採取した。また,特定健康診査に準拠した項目について,アンケートを行った。毛髪中のミネラル濃度は ICP-MSを用いて定量し,その結果とアンケートとの関連性はロジスティック回帰分析により,また,加齢とアンケートとの関連性はχ<sup>2</sup>検定により行い,有意水準は <i>p</i><0.05とした。なお,統計解析にはJMP ver.12(SAS Institute)を用いた。<br>【結果・考察】アンケート結果より,加齢に伴い有意に増大した項目としては,血圧,コレステロール,骨密度に関するものがあった。また,加齢に伴い体重の増加が認められたが,食習慣が悪い女性や一年以内に体重増減のあった女性は有意に減少した。この結果から,食習慣や運動習慣は,年代が低いほど悪いことがわかった。毛髪中のミネラル濃度とアンケートとの関連性において,特に,20代では習慣的な喫煙により,鉄以外の必須ミネラル濃度は増大し,有害ミネラル濃度は増減が認められた。また,40や50代では,体格や運動習慣,食習慣などの多くの項目と毛髪中のミネラル濃度との関連性が認められた。さらに,各年代において,疾病と毛髪中のミネラル濃度との間に特徴的な関連性を認めた。
  • Adsorption Capability of Calcined Gibbsite for V, Sr, and Mo from a Complex Solution System, Ogata Fumihiko, Kawasaki Naohito, Journal of Water and Environment Technology, 14, 5, 362, 371,   2016 , http://ci.nii.ac.jp/naid/130005249560
    Summary:<p>In this study, we have modified gibbsite, one of the mineral forms of aluminum hydroxide, by calcination at 400°C (GB400) to be used as an adsorbent. Properties of pristine gibbsite and GB400 have been investigated. Adsorption of V, Sr, and Mo onto GB400 and the effect of contact time and pH in solution on the adsorption process have been investigated using the adsorption isotherms. Desorption process and the selective adsorption and desorption of the metal ions in binary or ternary solution systems have also been monitored. Adsorption isotherms for V, Sr, and Mo were fitted well using the Langmuir equation in comparison to the Freundlich equation. Adsorption equilibrium for V, Sr, and Mo were attained within 12 h, 10 − 20 min, and 10 − 20 min, respectively. These data can be well described with a pseudo-second-order model than a pseudo-first-order model. V, Sr, and Mo adsorbed onto GB400 were easily desorbed (recovered) using hydrochloric acid or sodium hydroxide solutions of different concentrations. GB400 exhibits selective adsorption and desorption capacities in binary and ternary solution systems, which indicate that GB400 could be used for the selective recovery of rare metals from ternary (complex) solution systems.</p>
  • カルシウム欠乏卵巣摘出ラットを用いた永久硬水および一時硬水の骨形成効果に関する基礎研究, 緒方 文彦, 長井 紀章, 伊藤 吉將, 川崎 直人, 臨床環境医学, 24, 2, 94, 101,   2015 12 31 , http://jglobal.jst.go.jp/public/201702213643254960
    Summary:本研究では、卵巣摘出ラットを用いてミネラル水飲水量と骨粗鬆症との関連性について基礎的検討を実施した。給餌方法は、低カルシウム食と精製水(PW群)、低カルシウム食と永久硬水(PH群)および低カルシウム食と一時硬水(HT群)の3種類とした。実験開始3ヵ月後、PH群およびTH群の骨密度は、PW群のそれと比較し、高値を示した(p<0.05)。これらのことから、永久硬水および一時硬水は、骨量の維持に寄与していることが明らかとなった。さらに、実験開始3ヵ月後のPW群においては、実験開始直後と比較し、骨中および血中のカルシウムおよびマグネシウム濃度は減少傾向を示した。一方、PH群およびHT群では、骨中および血中のカルシウムおよびマグネシウム濃度を維持していた。PH群およびTH群では骨量の維持が可能であることが示唆された。また、PW群、PH群およびTH群間において血清カルカリフォスファターゼに有意な差は認められなかった。(著者抄録)
  • 大学生における運動能力の推移および体格・精神的健康状態と運動能力との関連性, KAWASAKI NAOTO, OGATA FUMIHIKO, 日本公衆衛生学会総会抄録集, 74th, 546, 546,   2015 10 15 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201502216429407187
  • 富栄養化防止を指向した大豆由来炭素材料およびポリグルタミン酸による窒素およびリンの同時除去に関する基礎研究, OGATA FUMIHIKO, KAWASAKI NAOHITO, 日本水環境学会シンポジウム講演集, 18th, 112,   2015 09 14 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201502207156833359
  • 鉄型ハイドロタルサイト(Fe‐HT)による亜ヒ酸イオンの吸着挙動, OGATA FUMIHIKO, IMAI DAISUKE, KAWASAKI NAOHITO, 衛生薬学・環境トキシコロジー講演要旨集, 2015, 135,   2015 08 31 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201602205075048120
  • 焼成水酸化ニッケルによるリン酸イオン吸着能に関する研究, KAWASAKI NAOHITO, OGATA FUMIHIKO, TODA MEGUMI, OTANI MASASHI, 衛生薬学・環境トキシコロジー講演要旨集, 2015, 158,   2015 08 31 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201602205290374659
  • 琵琶湖淀川水系における重金属の挙動と健康影響, OGATA FUMIHIKO, KAWASAKI NAOTO, メタルバイオサイエンス研究会講演要旨集, 2015, 31, 32,   2015 08 27 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201502211205869787
  • 水酸化コバルト焼成物へのリン酸イオンの吸着機構, IMAI DAISUKE, OGATA FUMIHIKO, TODA NOBORU, OTANI SHOJI, KAWASAKI NAOTO, メタルバイオサイエンス研究会講演要旨集, 2015, 44,   2015 08 27 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201502213126226342
  • Adsorption of phosphate ion in aqueous solutions by calcined cobalt hydroxide at different temperatures, Fumihiko Ogata, Daisuke Imai, Megumu Toda, Masashi Otani, Naohito Kawasaki, Naohito Kawasaki, Journal of Environmental Chemical Engineering, 3, 1570, 1577,   2015 06 27 , 10.1016/j.jece.2015.05.028, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84933057026&origin=inward
    Summary:© 2015 Elsevier B.V. All rights reserved. In this study, cobalt hydroxide (Co) was calcined at 130 and 150 °C (Co130 and Co150) and the physical properties of Co, Co130 and Co150 were investigated. Co, Co130, and Co150 were characterized by scanning electron microscopy, X-ray diffraction analysis, and thermogravimetric-differential thermal analysis, and the specific surface area, amount of hydroxyl groups, and surface pH were determined. Moreover, the phosphate adsorption capability of cobalt hydroxide and the cobalt hydroxide calcination products was evaluated via examination of the effect of contact time and solution pH, analysis of an adsorption isotherm, and a desorption study. The amount of hydroxyl groups on the adsorbent decreased in order Co (0.62 mmol/g) > Co130 (0.39 mmol/g) > Co150 (0.06 mmol/g). Similarly, the amount of phosphate ion adsorbed decreased in order Co (155.0 mg/g) > Co130 (120.0 mg/g) > Co150 (2.5 mg/g). These results indicated a linear correlation between the amount of phosphate ions adsorbed and the amount of hydroxyl groups on the adsorbent (correlation coefficient: 0.980). Adsorption kinetic data fit the pseudo-second-order kinetic model better than the pseudo-first-order model, and results from the adsorption isotherm studies suggested that phosphate ion adsorption can be well described by both the Freundlich and Langmuir equations. The ideal pH for phosphate ion adsorption was approximately in the range 6.0-9.0, and the mechanism for phosphate ion adsorption involved ion exchange with surface hydroxyl groups onto the adsorbent. Finally, the desorption results indicated that Co has promising potential for use as a renewable adsorbent.
  • Cationic dye removal from aqueous solution by waste biomass produced from calcination treatment of rice bran, Fumihiko Ogata, Daisuke Imai, Naohito Kawasaki, Naohito Kawasaki, Journal of Environmental Chemical Engineering, 3, 1476, 1485,   2015 06 26 , 10.1016/j.jece.2015.05.025, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84934295024&origin=inward
    Summary:© 2015 Elsevier Ltd. All rights reserved. Biomass-derived adsorbents, prepared from rice bran (RB) and treated by calcination at 600, 800, and 1000 °C (RB600, RB800, and RB1000), were characterized in terms of their properties. The adsorption of methylene blue (MB) and crystal violet (CV) on the biomass adsorbents was evaluated. The amount of MB and CV adsorbed was related to the physical properties of the adsorbent. For both dyes, the adsorption capacity increases with time, and the equilibrium time is about 8 and 48 h for uncalcined RB and RB1000, respectively. The adsorption kinetics of dyes is better described by a pseudo-second-order kinetic model. Moreover, the amount of MB or CV adsorbed onto uncalcined RB decreased with increasing temperature, whereas adsorption onto RB1000 increased with increasing temperature. The enthalpies implied by the temperature dependence were ΔH = -4.89 to -54.77 kJ/mol and 11.13-50.21 kJ/mol, for uncalcined RB and RB1000, respectively, which suggested that the adsorption of the dyes onto uncalcined RB or RB1000 should be regarded as physical adsorption, or between physical adsorption and chemical adsorption but dominated by physical adsorption. The equilibrium data of dyes fitted well to the Freundlich adsorption isotherm models. The amount of dyes adsorbed onto uncalcined RB or RB1000 increased at approximately pH 6.0 or http://dx.doi.org/10.0, respectively, which suggests that MB and CV were adsorbed on the surface of the adsorbent through interactions between the electrons of the negatively charged adsorbent surface and the cationic dyes in solution.
  • 女性における毛髪中の金属濃度と健康との関連性, KAWASAKI NAOTO, OGATA FUMIHIKO, 日本臨床環境医学会学術集会プログラム・抄録集, 24th, 63, 63,   2015 05 22 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201502200062530900
  • 女性における毛髪中の金属濃度と健康との関連性, 川崎 直人, 緒方 文彦, 日本臨床環境医学会総会プログラム・抄録集, 24回, 63, 63,   2015 05
  • 脱毛の簡易分類およびAGAに影響を及ぼす生活習慣の年代別傾向, KAWASAKI NAOTO, WATANABE NAOKO, TSUZUKI HIROAKI, KATO MIZURU, OKAMURA KATSUMASA, NAKAGAWA SONOKO, TAKADA KAORI, OGATA FUMIHIKO, YAMADA HIDEKAZU, 日本抗加齢医学会総会プログラム・抄録集, 15th, 240, 240,   2015 05 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201502219552417641
  • リン資源循環のためのコバルト‐ニッケル共沈水酸化物を用いたリン分離・回収剤の開発, IMAI DAISUKE, OGATA FUMIHIKO, KAWASAKI NAOHITO, TODA MEGUMU, OTANI MASASHI, 日本水環境学会年会講演集, 49th, 354,   2015 03 16 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201502219134787849
  • 焼成ギブサイトによる縮合リン酸の吸着能に関する基礎的検討, OGATA FUMIHIKO, IMAI DAISUKE, KAWASAKI NAOHITO, 日本水環境学会年会講演集, 49th, 309,   2015 03 16 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201502254406937586
  • 毛髪中の金属濃度の測定による健康維持・疾病予防への適用, 川崎 直人, 緒方 文彦, 石井 照樹, 今井 大輔, 岩田 淳, 日本薬学会年会要旨集, 135年会, 3, 226, 226,   2015 03
  • カルシウム欠乏卵巣摘出ラットを用いた高ミネラル水の骨形成促進効果に関する基礎研究, OGATA FUMIHIKO, NAGAI NORIAKI, ITO YOSHIMASA, KAWASAKI NAOHITO, 日本薬学会年会要旨集(CD-ROM), 135th, 3, ROMBUNNO.28PA-AM052, 221,   2015 03 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201502289192020610
  • カルシウム欠乏卵巣摘出ラットを用いた高ミネラル水の骨形成促進効果に関する基礎研究, 緒方 文彦, 長井 紀章, 伊藤 吉將, 川崎 直人, 日本薬学会年会要旨集, 135年会, 3, 221, 221,   2015 03
  • 毛髪中の金属濃度の測定による健康維持・疾病予防への適用, KAWASAKI NAOHITO, OGATA FUMIHIKO, ISHII TERUKI, IMAI DAISUKE, IWATA JUN, 日本薬学会年会要旨集(CD-ROM), 135th, 3, ROMBUNNO.28PA-AM081, 226,   2015 03 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201502251502645716
  • 数種の吸着剤を用いた変敗油脂の再生に関する基礎的検討, SASAKI TERU, OGATA FUMIHIKO, TANIWAKI TAKANORI, KAWASAKI NAOHITO, 日本薬学会年会要旨集(CD-ROM), 135th, ROMBUNNO.28PA-AM120,   2015 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201502289778196904
  • ポリエチレンテレフタラートを用いたニッケル‐コバルト共沈水酸化物の造粒およびそのリン酸イオン吸着能との関連性, KAWAKAMI YUHI, IMAI DAISUKE, OTANI SHOJI, TODA TOKU, OGATA FUMIHIKO, KAWASAKI NAOHITO, 日本薬学会年会要旨集(CD-ROM), 135th, ROMBUNNO.28PA-AM099,   2015 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201502261392911526
  • 多成分系における数種のニッケル水酸化物を用いたリン酸吸着能に関する基礎研究, UEDA ERIMI, IMAI DAISUKE, OGATA FUMIHIKO, KAWASAKI NAOHITO, 日本薬学会年会要旨集(CD-ROM), 135th, ROMBUNNO.28PA-AM100,   2015 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201502205127471967
  • Properties of novel adsorbent produced by hydrothermal treatment of waste fly ash in alkaline solution and its capability for adsorption of tungsten from aqueous solution, Fumihiko Ogata, Yuka Iwata, Naohito Kawasaki, Naohito Kawasaki, Journal of Environmental Chemical Engineering, 3, 333, 338,   2015 01 01 , 10.1016/j.jece.2014.11.015, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84920397190&origin=inward
    Summary:© 2014 Elsevier Ltd. All rights reserved. Zeolites were produced by hydrothermal treatment of fly ash for 48, 60, and 72 h (referred to as FA48, FA60, and FA72) in alkaline solution. Physical and chemical analyses were performed on the FA samples. Moreover, the amount of tungsten adsorbed on the FA samples, derived from the adsorption isotherms under different pH conditions, and the effect of the contact time on the adsorption were evaluated. Parent FA consisted primarily of mullite crystals, whereas the hydrothermally treated FA48, FA60, and FA72 samples consisted of phillipsite, zeolite X, and zeolite A, respectively. The specific surface areas and pore volumes of parent FA were smaller than those of FA48, FA60, and FA72. FA48 generated the largest specific surface area and pore volume. The saturated amount of tungsten adsorbed on FA48 was greater than that of the other FA samples. Tungsten adsorption was more effective (larger amount) at pH 2.0-3.0 than at pH 6.1-6.5 or pH 11.0-12.0. These results suggest that the tungsten was adsorbed on the surface of FA48 through interactions between the electrons of the positively charged FA48 surface and the tungsten anions in solution. Analysis of the equilibrium adsorption data using the Langmuir and Freundlich equations showed that the correlation coefficient of the Freundlich isotherm was higher than that of the Langmuir model. The data obtained in this study fit more adequately to the pseudo-second-order model than the pseudo-first-order model. Collectively, these results suggest that FA48 is prospectively useful for the adsorption of tungsten from aqueous solutions.
  • Kinetic and Equilibrium Investigations of Cobalt(II), Nickel(II), and Tungsten(VI) Adsorption on Fly Ash Processed by Hydrothermal Treatment in an Alkaline Solution, OGATA Fumihiko, IWATA Yuka, KAWASAKI Naohito, Journal of Water and Environment Technology, 13, 5, 359, 370,   2015 , http://ci.nii.ac.jp/naid/130005103404
    Summary:The adsorption of tungsten(VI) from a single solution onto zeolite fly ash (FA60) produced by hydrothermally treating fly ash (FA) in alkaline solution had been reported. However, taking into account practical considerations, the tungsten(VI) adsorption from a complex solution system containing cobalt, nickel, and tungsten should be investigated. In this study, the amounts of cobalt(II), nickel(II), and tungsten(VI) adsorbed onto the FA and FA60 surfaces were evaluated for a complex solution system. It was observed that a higher amount of tungsten(VI) was adsorbed onto the FA60 surface than onto the FA surface. The adsorption isotherms for tungsten(VI) were fitted using both the Freundlich and Langmuir equations. The result suggest that tungsten(VI) was adsorbed onto the FA and FA60 surfaces through electrostatic interactions between the positively charged FA or FA60 surfaces and the tungsten(VI) anions in complex solution. The pseudo-second-order model described the data more accurately than the pseudo-first-order model. The data obtained for various contact times indicated that the adsorption of tungsten(VI) proceeded through a multistep process involving the adsorption of tungsten(VI) onto the external surface and its subsequent diffusion into the interior of the absorbent. These results suggest that FA60 has a promising potential for the adsorption of tungsten(VI) in complex solution.
  • ブリスコールによる油中酸性化合物の吸着除去に関する研究, TANIWAKI TAKANORI, KAMAI IKKI, BANDO AKITO, OGATA FUMIHIKO, KAWASAKI NAOTO, 日本油化学会年会講演要旨集, 53rd, 143,   2014 09 09 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201402246370961280
  • Adsorption of phosphate ions from aqueous solution of nickel hydroxides calcined at different temperatures, Fumihiko Ogata, Daisuke Imai, Megumu Toda, Masashi Otani, Naohito Kawasaki, e-Journal of Surface Science and Nanotechnology, 12, 0, 404, 409,   2014 08 30 , 10.1380/ejssnt.2014.404, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84908246914&origin=inward
    Summary:© 2014 The Surface Science Society of Japan. Nickel hydroxide (Ni100) and nickel hydroxide, including cobalt (NiCo91), were calcined at different temperatures. These materials were investigated by analyzing data obtained from X-ray diffraction (XRD), scanning electron microscopy, specific surface area, thermogravimetric-differential thermal (TG-DTA) technique, and electron-probe microanalysis. The XRD and TG-DTA data obtained indicated that calcination at 250-270°C can promote the conversion of Ni(OH)2 into NiO, and that cobalt hardly affected the structural changes of nickel hydroxide. The specific surface areas of Ni100 and NiCo91 were determined to be in the range 17.9-148.3 and 21.0-145.1 m2/g, respectively. The specific surface area increased suddenly at 260°C. The amount of phosphate adsorbed onto Ni100 and NiCo91 was measured to be in the range 29.2-44.7 and 29.7-54.0 mg/g, respectively. The amount adsorbed onto Ni100 or NiCo91 was greater than that onto another adsorbent previously reported. The correlation coefficient relationships between the specific surface areas of Ni100 and NiCo91 and the saturated amount of the adsorbed phosphate ions were found to be 0.935 and 0.960, respectively. These results suggested that adsorption of phosphate ions with Ni100 or NiCo91 is related to the specific surface area. Our study demonstrated that Ni100 and NiCo91 can be considered as promising materials for the adsorption of phosphate ions from aqueous solutions.
  • ケイ酸マグネシウム(ブリスコール)による食用油の劣化抑制に関する研究, TANIWAKI TAKANORI, KAMAI KAZUKI, BANDO AKIHITO, OGATA FUMIHIKO, KAWASAKI NAOTO, 日本食品科学工学会大会講演集, 61st, 166,   2014 08 28 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201402207907916370
  • デキストリン併用投与がクレメジン細粒経管投与時の低回収率およびチューブ詰まりに与える影響, 長井 紀章, 緒方 文彦, 塚本 あゆみ, 林 友典, 西浦 早織, 松岡 寛, 小竹 武, 川崎 直人, 伊藤 吉將, 薬局薬学, 6, 1, 22, 27,   2014 04
    Summary:クレメジン細粒は簡易懸濁法を用いた経管投与として患者に適応される医薬品であるが、その際にみられる器具内薬物残存およびチューブ詰まりが問題視されている。本研究では、分散性の向上能を有するデキストリンを用い、クレメジン細粒の簡易懸濁法時における器具内薬物残存およびチューブ詰まりの改善効果ついて検討を行った。0.6%デキストリンにてクレメジン細粒を懸濁したところ、精製水にて懸濁した場合と比較し有意に分散および流動性の増加が認められた。一方、0.1%または0.2%デキストリンにてクレメジン細粒を懸濁した場合の分散および流動性は精製水のそれと同程度であった。また、0.1および0.2%のデキストリン添加ではクレメジン細粒簡易懸濁法による経管投与時の回収率は精製水にて懸濁した際と差はなかったが、0.6%デキストリン添加では、精製水にて懸濁した際のものと比較し、高い回収率を示した。(著者抄録)
  • 焼成ギブサイトによる抗がん剤(シスプラチン)の除去に関する基礎的研究, OGATA FUMIHIKO, KAWASAKI NAOHITO, 日本水環境学会年会講演集, 48th, 178,   2014 03 17 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201402220284796693
  • ベシル酸アムロジピン製剤を用いた簡易懸濁法適用時における吸着剤の影響, OGATA FUMIHIKO, NAGAI NORIAKI, HAYASHI TOMONORI, NISHIURA SAORI, MATSUOKA HIROSHI, ITO YOSHIMASA, KAWASAKI NAOTO, 日本薬学会年会要旨集(CD-ROM), 134th, 3, ROMBUNNO.28PML-103, 244,   2014 03 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201402220771359142
  • 富栄養化防止を指向した高速水質浄化システムの実証研究, KAWASAKI NAOHITO, OGATA FUMIHIKO, UEDA AYAKA, 日本薬学会年会要旨集(CD-ROM), 134th, 3, ROMBUNNO.28PML-052, 236,   2014 03 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201402262995009540
  • Zeolite X produced by hydrothermal treatment of fly ash in an alkaline solution, Fumihiko Ogata, Yuka Iwata, Naohito Kawasaki, e-Journal of Surface Science and Nanotechnology, 12, 0, 23, 25,   2014 02 08 , 10.1380/ejssnt.2014.23, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84893851748&origin=inward
    Summary:Fly ash (FA) was hydrothermally treated in an alkaline solution to produce zeolite X (Z-FA). The properties of the FA and Z-FA were then investigated. The FA consisted of spherical particles of various diameters. The X-ray diffraction patterns of FA and Z-FA showed that the FA mainly consisted of mullite crystals (3Al2O3·2SiO2), while the Z-FA consisted of zeolite crystals. The specific surface area (23.3 m2/g) and pore volume (57.6 μL/g) of the Z-FA were greater than those of the FA (2.7 m 2/g and 12.7μL/g, respectively). The pHpzc of the FA and Z-FA were 7.94 and 9.81, respectively. © 2014 The Surface Science Society of Japan.
  • Removal of Phosphate Ions by PGAF (Poly-γ-Glutamic Acid and Flocculants), OGATA Fumihiko, UEDA Ayaka, KAWASAKI Naohito, Journal of Water and Environment Technology, 12, 5, 447, 458,   2014 , http://ci.nii.ac.jp/naid/130004694038
    Summary:Poly-&gamma;-glutamic acid and flocculants (PGAF) were prepared for the removal of phosphate ions from aqueous solution. Scanning electron microscopy images of PGAF were obtained, and the amounts of calcium and oxygen on the PGAF surface were confirmed by electron probe microanalysis. The removal percentage of phosphate ions by PGAF was 98.2% within 10 min. Hydroxyapatite (Ca<SUB>10</SUB>(PO<SUB>4</SUB>)<SUB>6</SUB>(OH)<SUB>2</SUB>) and calcite (calcium carbonate) were produced by adding PGAF to a phosphate ion solution. These products were collected using poly-&gamma;-glutamic acid and precipitated in aqueous solution. The results suggest that the removal rate of phosphate ions is very fast, and solid/liquid separation is achieved very easily using PGAF. Moreover, the removal of phosphate ions by PGAF increased as the amount of adsorbent was increased. The optimal agitation speed for the removal of phosphate ions was 60 - 120 rpm, whereas the temperature and solution pH did not affect the removal of phosphate ions. Therefore, PGAF may be useful for the removal of phosphate ions from aqueous solution.
  • Use of Calcined Gibbsite to Remove Cisplatin from Aqueous Solutions, OGATA Fumihiko, INOUE Kenji, TOMINAGA Hisato, IWATA Yuka, UEDA Ayaka, TANAKA Yuko, KAWASAKI Naohito, Journal of Water and Environment Technology, 12, 1, 13, 23,   2014 , http://ci.nii.ac.jp/naid/130003391640
    Summary:In the present study, GB400 was prepared by calcination of gibbsite (GB) at 400&deg;C. The properties of GB and GB400 were investigated and the adsorption of cisplatin onto GB400 was evaluated. The scanning electron microscopy images were obtained and specific surface area, mean pore diameter, pore volume, number of hydroxyl groups, and the solution pH were measured. The observed values for GB400 were superior to those of GB. The optimal pH condition for adsorption of cisplatin using GB400 was about 8. Equilibrium adsorption of cisplatin onto GB400 was reached within 24 h. These experimental data were fitted to the pseudo-second-order equation. Moreover, the amount of cisplatin adsorbed onto GB400 was increased proportionally with temperature. The experimental data were fitted to the Langmuir equation model. The <I>&Delta;G</I> values were less than -80 kJ/mol, which indicate that the adsorption mechanism of cisplatin onto GB400 is related to chemisorption. The <I>&Delta;H</I> values were negative, indicating that the adsorption of cisplatin onto GB400 is exothermic. The positive values of <I>&Delta;S</I> signify an irregular increase of the randomness at the GB400/solution interface during the adsorption process. Cisplatin adsorbed onto GB400 was desorbed using hydrochloric acid solution.
  • Adsorption of Pt(IV) and Pd(II) by calcined dried aluminum hydroxide gel from aqueous solution system, Fumihiko Ogata, Naohito Kawasaki, Journal of Environmental Chemical Engineering, 1, 1013, 1019,   2013 12 01 , 10.1016/j.jece.2013.08.011, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84888404592&origin=inward
    Summary:In this study, calcined dried aluminum hydroxide gels (Gs) were prepared at 300-1000 C (G300-G1000) as adsorbents. The properties of the adsorbents (i.e., XRD patterns, SEM images, specific surface areas, and number of hydroxyl groups) were investigated. The adsorption of Pt(IV) and Pd(II) onto Gs at different temperatures was evaluated. Calcination transformed virgin G into γ- and α-alumina. G600 had the largest specific surface area (107.2 m 2/g) and number of hydroxyl groups (1.12 mmol/g) of the Gs. G600 also adsorbed the greatest amount of Pt(IV) and Pd(II). The amount of Pt(IV) and Pd(II) adsorbed was more closely related to the number of hydroxyl groups than the specific surface area. The adsorption mechanism of Pt(IV) and Pd(II) onto G600 mainly involved ion exchanges. The optimal pH for the adsorption of Pt(IV) and Pd(II) onto G600 was ∼5.0, which suggests that [PtCl5(OH)] 2- and [PdCl3(OH)]2- species are suitable for adsorption. Pt(IV) and Pd(II) compete with chloride ions for adsorption sites on G600 in the aqueous solution system. The adsorption of Pt(IV) and Pd(II) onto G600 reached equilibrium within 24 h. The experimental data fit the pseudo-second-order model (correlation coefficient: 0.986-0.995) better than the pseudo-first-order model (correlation coefficient: 0.879-0.973). Moreover, the Weber-Morris plot also was evaluated. The adsorption isotherms of Pt(IV) and Pd(II) onto G600 fit the Freundlich and Langmuir models, respectively. Thus, G600 is useful for the adsorption of Pt(IV) and Pd(II) in aqueous solution. © 2013 Elsevier Ltd. All rights reserved.
  • ポリエチレンテレフタラートを用いた新規造粒ベーマイトの創製およびそのリン酸吸着能, OGATA FUMIHIKO, KAWASAKI NAOHITO, 日本水環境学会シンポジウム講演集, 16th, 259,   2013 11 09 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201302255867711824
  • ケイ酸カルシウム処理による食用油の変敗抑制に関する研究, OGATA FUMIHIKO, BANDO AKIHITO, TANIWAKI TAKANORI, HORIKE HIROFUMI, KAWASAKI NAOHITO, 日本油化学会年会講演要旨集, 52nd, 197,   2013 09 03 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201302253970814493
  • ケイ酸マグネシウム(ブリスコール)による食用油の劣化抑制に関する研究, TANIWAKI TAKANORI, HORIKE HIROFUMI, BANDO AKIHITO, OGATA FUMIHIKO, KAWASAKI NAOHITO, 日本油化学会年会講演要旨集, 52nd, 217,   2013 09 03 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201302287487941842
  • Lead (II) adsorption on chemically modified activated carbon in aqueous solution, Fumihiko Ogata, Yuka Iwata, Naohito Kawasaki, e-Journal of Surface Science and Nanotechnology, 11, 0, 93, 98,   2013 08 31 , 10.1380/ejssnt.2013.93, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84885075569&origin=inward
    Summary:In the present study, we developed modified activated carbon (KL) for the adsorption of Pb (II). Chemically modified activated carbons (KL-A and KL-B) were prepared by nitric acid and ethylenediamine treatments, respectively. The properties (specific surface area, pore volume, mean pore diameter, acidic or basic functional groups, and pH) of KL, KL-A, and KL-B were investigated by various methods. Contact time, adsorption isotherms, and recovery of Pb (II) were evaluated. Equilibrium adsorption on KL and KL-B or KL-A was reached in about 12 h and 5 h, respectively. The experimental data was fitted to pseudo-second order model and compared with the pseudo-first order model. The optimal pH conditions for the adsorption of Pb (II) was pH = 5.1-5.5. These data were fitted to Freundlich and Langmuir models. Moreover, the adsorption mechanism of Pb (II) on KL-A was related to the ion exchange with acidic functional groups. It would be possible to recover Pb (II) by using nitric acid. The results suggest that KL-A would be useful in the adsorption of Pb (II). © 2013 The Surface Science Society of Japan.
  • フライアッシュ由来ゼオライトを用いた多成分系におけるタングステン吸着能の評価, IWATA YUKA, OGATA FUMIHIKO, KAWASAKI NAOHITO, 衛生薬学・環境トキシコロジー講演要旨集, 2013, 137,   2013 08 26 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201302247935700744
  • オリーブ油およびトコフェロール添加による大豆油の変敗抑制効果, TANAKA YUKO, OGATA FUMIHIKO, KAWASAKI NAOHITO, 衛生薬学・環境トキシコロジー講演要旨集, 2013, 133,   2013 08 26 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201302253978860702
  • 富栄養化防止を指向した高速水質浄化システムの開発, UEDA AYAKA, OGATA FUMIHIKO, KAWASAKI NAOHITO, 衛生薬学・環境トキシコロジー講演要旨集, 2013, 126,   2013 08 26 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201302294469502382
  • Development of actual dyestuff wastewater treatment by ozone with carbonaceous materials produced from waste fiber, Naohito Kawasaki, Hisato Tominaga, Fumihiko Ogata, Sen'i Gakkaishi, 69, 125, 131,   2013 08 05 , 10.2115/fiber.69.125, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84880885330&origin=inward
    Summary:The methylene blue and dyestuff removal efficiency in a textile factory by ozonation and/or carbonaceous material treatment was investigated. Three kinds of carbonaceous materials were prepared from wool (WL), polyester (PET), and cotton (CT) discharged from the textile factory. The physical properties of the carbonaceous materials were very different. The specific surface area and pore volume of WL were the lowest, while those of CT were the highest. The dyestuff removal efficiency from actual dyestuff water was the highest when using the carbonaceous material (CT) prepared from cotton waste fiber. The decreases in the chromaticity, turbidity, COD, and TOC of the actual dyestuff wastewater depended upon the mean pore diameter of the carbonaceous material. The COD and TOC of the actual dyestuff wastewater were only slightly decreased by ozonation. The ozonation with CT would be useful for the removal of the dyestuff from actual textile wastewater. These results indicated that the waste cotton fiber could be converted into a carbonaceous material as an adsorbent for the removal of dyestuff from actual wastewater.
  • Evaluation of Moisture Adsorbent Produced from Fly Ash and Its Adsorption Ability of Moisture, OGATA Fumihiko, TOMINAGA Hisato, IWATA Yuka, UEDA Ayaka, TANAKA Yuko, KAWASAKI Naohito, 化学工学論文集 = Kagaku kogaku ronbunshu, 39, 3, 231, 237,   2013 07 20 , 10.1252/kakoronbunshu.39.231, http://ci.nii.ac.jp/naid/10031188054
    Summary:Moisture adsorbent was prepared from fly ash treated by heating (FA, FA300, FA500, and FA700) or alkaline hydration (FA48, FA60, and FA72). Ash content, specific surface area, pore volume, mean pore diameter, X-ray diffraction, and scanning electron microscopy of the adsorbents were investigated. Among the adsorbents, FA60 had the highest specific surface area (85.7 m<sup>2</sup>/g) and the highest amount of moisture adsorbed/desorbed, which indicated that adsorption mechanism was related to the specific surface area, the pore volume, and hydrophilicity or hydrophobicity of adsorbent. Adsorption/desorption isotherms of moisture were fitted to the BET equation. FA60 had a humidity control capacity of 116.8 mg/g and was usable for repeated adsorption/desorption of moisture. The results suggest that moisture adsorbent prepared from fly ash has the potential for practical application.
  • Evaluation of Moisture Adsorbent Produced from Fly Ash and Its Adsorption Ability of Moisture, Ogata Fumihiko, Tominaga Hisato, Iwata Yuka, Ueda Ayaka, Tanaka Yuko, Kawasaki Naohito, Chemical engineering, 39, 3, 231, 237,   2013 05 01 , 10.1252/kakoronbunshu.39.231, http://ci.nii.ac.jp/naid/130003365343
    Summary:Moisture adsorbent was prepared from fly ash treated by heating (FA, FA300, FA500, and FA700) or alkaline hydration (FA48, FA60, and FA72). Ash content, specific surface area, pore volume, mean pore diameter, X-ray diffraction, and scanning electron microscopy of the adsorbents were investigated. Among the adsorbents, FA60 had the highest specific surface area (85.7 m2/g) and the highest amount of moisture adsorbed/desorbed, which indicated that adsorption mechanism was related to the specific surface area, the pore volume, and hydrophilicity or hydrophobicity of adsorbent. Adsorption/desorption isotherms of moisture were fitted to the BET equation. FA60 had a humidity control capacity of 116.8 mg/g and was usable for repeated adsorption/desorption of moisture. The results suggest that moisture adsorbent prepared from fly ash has the potential for practical application.
  • Adsorption of Pt(IV) and Pd(II) from aqueous solution by calcined gibbsite (Aluminum Hydroxide), Fumihiko Ogata, Kenji Inoue, Hisato Tominaga, Yuka Iwata, Ayaka Ueda, Yuko Tanaka, Naohito Kawasaki, e-Journal of Surface Science and Nanotechnology, 11, 0, 40, 46,   2013 03 23 , 10.1380/ejssnt.2013.40, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84875542746&origin=inward
    Summary:In the present study, calcined gibbsite (GB) was prepared by calcination treatment between 200 and 1000°C (GB200-GB1000). The properties of GBs (i.e., the amount of hydroxyl groups, specific surface area, mean pore diameter, and pore volume) were evaluated. GB400 had the highest amount of hydroxyl groups (0.46 mmol/g), as well as the highest specific surface area (295.3 m2/g) and micropore volume (0.036 mL/g). It also provided the highest amount of the adsorbed Pt(IV) and Pd(II), which suggests that the adsorption of Pt(IV) and Pd(II) onto GB is related to the amount of hydroxyl groups, specific surface area, and micropore volume. The optimal pH values for the adsorption of Pt(IV) and Pd(II) onto GB400 were 4.5-5.0 and about 6.0, respectively. The equilibrium adsorption of both cations onto GB400 was reached within 30 min. Moreover, the experimental data of the adsorption of Pt(IV) and Pd(II) onto GB400 was fitted by pseudo-second-order model (r = 0:997-0.999) and the Langmuir equation (r = 0:934-0.953). The calculated thermodynamic parameters δG, δH, and, δS indicate that the adsorption of Pt(IV) onto GB400 is feasible, spontaneous, and exothermic. In addition, the amount of Pt(IV) and Pd(II) adsorbed onto GB400 decreased with increasing chloride ion concentration. © 2013 The Surface Science Society of Japan.
  • 大学教職員を対象とした特定健診における腹囲測定と生活状況調査の有用性, TOMINAGA HISAHITO, OGATA FUMIHIKO, SAGAWA KAZUNORI, KINOSHITA MITSUHIRO, KAKEHI KAZUAKI, KAWASAKI NAOHITO, 日本薬学会年会要旨集(CD-ROM), 133rd, 3, ROMBUNNO.30AME-184, 251,   2013 03 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201302201374762923
  • 大学教職員を対象とした特定健診における腹囲の測定評価と生活状況調査の有用性, KAWASAKI NAOHITO, TOMINAGA HISAHITO, OGATA FUMIHIKO, SAGAWA KAZUHIKO, 日本薬学会年会要旨集(CD-ROM), 133rd, 3, ROMBUNNO.30AME-185, 251,   2013 03 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201302244619885180
  • 食用油へのトコフェロール添加による劣化抑制に関する基礎的研究, TANAKA YUKO, OGATA FUMIHIKO, TOMINAGA HISAHITO, KAWASAKI NAOTO, 日本薬学会年会要旨集(CD-ROM), 133rd, 3, ROMBUNNO.29AME-068, 232,   2013 03 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201302262166457628
  • 配合剤を使用した簡易懸濁時における主成分溶出能に関する基礎的検討, OGATA FUMIHIKO, HAYASHI TOMONORI, NISHIURA SAORI, MATSUOKA HIROSHI, KAKEHI KAZUAKI, KAWASAKI NAOHITO, 日本薬学会年会要旨集(CD-ROM), 133rd, 3, ROMBUNNO.30PME-253, 263,   2013 03 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201302229745825844
  • ポリグルタミン酸を用いた水浄化剤によるリン酸の高速吸着に関する研究, UEDA AYAKA, OGATA FUMIHIKO, TOMINAGA HISAHITO, KAWASAKI NAOHITO, 日本薬学会年会要旨集(CD-ROM), 133rd, ROMBUNNO.30S-AM08,   2013 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201302219032586879
  • 表面改質酸化水酸化アルミニウムによる富栄養化の防止対策, KAWASAKI NAOHITO, OGATA FUMIHIKO, KABAYAMA MINEAKI, エネルギー・資源学会研究発表会講演論文集(CD-ROM), 32nd, ROMBUNNO.1-1,   2013 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201302255186400707
  • フライアッシュのアルカリ水熱反応による再資源化およびタングステンの吸着挙動, IWATA YUKA, TOMINAGA HISAHITO, OGATA FUMIHIKO, KAWASAKI NAOHITO, 日本薬学会年会要旨集(CD-ROM), 133rd, ROMBUNNO.30S-AM09,   2013 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201302290743072149
  • Preventive Effect of Dextrin on Residue in Syringe and Tube Obstruction for Kalimate® in the Simple Suspension Method by Feeding Tube, Nagai Noriaki, Ogata Fumihiko, Hayashi Tomonori, Nishiura Saori, Matsuoka Hiroshi, Kawasaki Naohito, Ito Yoshimasa, Japanese Journal of Hospital Pharmacy, 39, 1, 33, 38,   2013 , 10.5649/jjphcs.39.33, http://ci.nii.ac.jp/naid/130004502778
    Summary:Kalimate® is often administered to patients via a simple suspension method by feeding tube. However, this method has a low recovery ratio and tube obstruction can occur. In this study, we investigated whether adding dextrin to decrease the adhesiveness and dispersibility improves the low recovery ratio and reduce tube obstruction. The addition of 0.6% dextrin significantly increased the dispersibility and fluidity of kalimate® compared to the dispersibility and fluidity of kalimate in purified water, but the addition of 0.1% and 0.2% dextrin did not. On the other hand, the 0.1 - 0.6% dextrin improved the low recovery ratio of kalimate® in the simple suspension method by feeding tube. These results show that the addition of dextrin improves the low recovery ratio and prevents tube obstruction in the simple suspension method of kalimate®. In addition, it was suggested that the decrease in recovery ratio of kalimate® is related to the adhesiveness, and the increase of dispersibility suppressed the tube obstruction in the simple suspension method by feeding tube. These findings provide significant information that can be used in improving the low recovery ratio and tube obstruction in the simple suspension method by feeding tube.
  • Granulation of Boehmite without a Binder and its Capacity for Phosphate Adsorption in Aqueous Solution, OGATA Fumihiko, TOMINAGA Hisato, IWATA Yuka, UEDA Ayaka, TANAKA Yuko, KAWASAKI Naohito, Journal of Water and Environment Technology, 11, 3, 225, 234,   2013 , http://ci.nii.ac.jp/naid/130003363023
    Summary:In this study, GA (granulated aluminum oxyhydroxide) was prepared from aluminum oxyhydroxide without a binder, and its phosphate adsorption capacity was investigated. Scanning electron microscopy images, specific surface area, pore volume, mean pore diameter, and solution pH of GA were analyzed. The amount of phosphate adsorbed was studied using batch techniques, and was shown to increase at higher temperatures. Moreover, adsorption isotherms were fitted to both the Freundlich equation (correlation coefficient: 0.866 - 0.972) and the Langmuir equation (correlation coefficient: 0.993 - 0.999). Adsorption equilibrium was reached within 24 h. The kinetic data for adsorption was best described by a pseudo-first-order rate equation. A pH of about 3 was the most suitable for phosphate adsorption. Moreover, the adsorption mechanism of phosphate onto GA could be related to the specific surface area and surface hydroxyl groups on GA. Both adsorption and desorption could be performed on GA using NaOH at different concentrations. These results suggest that the GA prepared in this work is appropriate for practical applications.
  • 大学生の生活習慣と体力・運動能力との関連性に関する調査研究, TOMINAGA HISATO, SAGAWA KAZUNORI, OGATA FUMIHIKO, KAWASAKI NAOHITO, 衛生薬学・環境トキシコロジー講演要旨集, 2012, 335,   2012 10 13 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201302247292125453
  • 多成分系におけるコーヒー豆かす由来炭素材料によるアニオン吸着能, OGATA FUMIHIKO, TOMINAGA HISATO, KANGAWA MOE, INOUE KENJI, KAWASAKI NAOHITO, 衛生薬学・環境トキシコロジー講演要旨集, 2012, 283,   2012 10 13 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201302276150876192
  • Production of granulated boehmite by compression and its adsorption of phosphate in a single-solution system, Fumihiko Ogata, Hisato Tominaga, Yuka Iwata, Ayaka Ueda, Yuko Tanaka, Naohito Kawasaki, e-Journal of Surface Science and Nanotechnology, 10, 0, 518, 520,   2012 09 22 , 10.1380/ejssnt.2012.518, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84867202312&origin=inward
    Summary:In this study, powdered boehmite (AlO(OH)) was compressed to obtain a granulated form without using a binder. The granulated product was assessed via SEM imagery, TG-DTA, specific surface area, surface pH, and hydroxyl groups. The SEM images showed that powdered BE could be successfully granulated by compression without binders. TG-DTA showed that dehydration of adhesion and bound water occurred at 96.0 and 394.6°C, respectively. The amount of phosphate adsorbed onto granulated boehmite increased with temperature, indicating a chemisorption mechanism. Moreover, equilibrium adsorption was reached within 20-24 h. Adsorption kinetics data was fitted to the pseudo-second-order model. © 2012 The Surface Science Society of Japan.
  • 新規造粒ベーマイトによるリン酸吸着能に関する基礎的検討, OGATA FUMIHIKO, TOMINAGA HISATO, KABAYAMA MINEAKI, KAWASAKI NAOHITO, 日本水環境学会シンポジウム講演集, 15th, 209,   2012 09 10 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201202258683064119
  • Adsorption of nitrate, nitrite, and fluoride ions by carbonaceous material produced from coffee grounds in a complex solution system, Fumihiko Ogata, Hisato Tominaga, Moe Kangawa, Kenji Inoue, Yuko Tanaka, Ayaka Ueda, Yuka Iwata, Naohito Kawasaki, e-Journal of Surface Science and Nanotechnology, 10, 0, 493, 498,   2012 09 08 , 10.1380/ejssnt.2012.493, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84866351983&origin=inward
    Summary:Carbonaceous materials produced from coffee ground (virgin CG, CG600, CG800, and CG1000) were prepared. Specific surface areas, mean pore diameters, pore volumes, and SEM images of the CGs were investigated. The specific surface areas were in the order CG1000 (23.5 m 2/g) < CG800 (31.5 m 2/g) < CG600 (52.6 m 2/g), and the mean pore diameters were in the order CG600 (77.0 Å) < CG800 (139.3 Å) < CG1000 (273.8 Å). The amounts of nitrate, nitrite, and fluoride ions adsorbed in a single solution system were greater than the amounts adsorbed in a ternary solution system; this indicated that the ions were competitively adsorbed onto the CGs in the complex solution system. Moreover, the adsorption mechanism was ion exchange with chloride ion onto the CGs in a 1:1 ratio. Adsorption isotherms were fitted to both the Freundlich equation and the Langmuir equation. The amounts adsorbed increased with increasing temperature. The adsorption affinities onto the CGs were in the order nitrate ion < nitrite ion < fluoride ion. The most suitable breakthrough curve conditions were Space velocity: 4.24 1/h and Linear velocity: 0.38 m/h. Thus, carbonaceous materials produced from coffee grounds were useful for the adsorption of nitrate, nitrite, and fluoride ions in a ternary solution system. © 2012 The Surface Science Society of Japan.
  • Evaluation of carbonaceous material produced from fireproofed cotton and its adsorption of Methylene blue, Fumihiko Ogata, Hisato Tominaga, Moe Kangawa, Kenji Inoue, Yuko Tanaka, Yuka Iwata, Ayaka Ueda, Naohito Kawasaki, e-Journal of Surface Science and Nanotechnology, 10, 0, 374, 378,   2012 07 21 , 10.1380/ejssnt.2012.374, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84864433123&origin=inward
    Summary:We report herein on the fabrication of carbonaceous material produced from cotton treated with Tricresyl phosphate (TCP) for fireproofing and its evaluation for adsorbing Methylene blue (MB). We prepared two carbonaceous materials: cotton calcined at 900 ? C (CT900) and cotton calcined at 900 ? C with TCP (F-CT900). These materials were evaluated in terms of their scanning electron microscope images, specific surface area, pore volume, mean pore diameter, and solution pH. We found that the specific surface area of F-CT900 (1492 m2/g) is greater than that of CT900 (910 m2/g), and that the mean pore diameter of F-CT900 (2.41 ?A) is smaller than that of CT900 (9.09 ?A). The adsorption of MB onto CT900 and F-CT900 reached equilibrium within 5 h. We fitted the experimental data with the pseudo-second-order model and obtained correlation coefficients between 0.993 and 0.999. We found that more MB adsorbed onto F-CT900 (about 650 mg/g) than onto CT900 (about 350 mg/g). We also fitted these experimental data with both the Freundlich and Langmuir equations. Thus, carbonaceous material for MB removal could be produced from fireproofed cotton, and it is useful for the purification of dye solution systems. © 2012 The Surface Science Society of Japan.
  • バイオ吸着剤による有害重金属カドミウムおよび鉛の除去能, SAMUKAWA MOE, OGATA FUMIHIKO, TOMINAGA HISAHITO, INOUE KENJI, KAWASAKI NAOTO, 日本薬学会年会要旨集, 132nd, 3, 231, 231,   2012 03 05 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201202216138434877
  • 啓発活動による大学生の朝食欠食改善に関する調査研究, TOMINAGA HISAHITO, OGATA FUMIHIKO, SAGAWA KAZUNORI, KINOSHITA MITSUHIRO, KAKEHI KAZUAKI, KAWASAKI NAOTO, 日本薬学会年会要旨集, 132nd, 3, 228, 228,   2012 03 05 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201202216925590258
  • 大学生を対象とした食習慣および体格誤認改善のための介入研究, KAWASAKI NAOHITO, TOMINAGA HISAHITO, OGATA FUMIHIKO, SAGAWA KAZUNORI, KINOSHITA MITSUHIRO, KAKEHI KAZUAKI, 日本薬学会年会要旨集, 132nd, 3, 262, 262,   2012 03 05 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201202274143736903
  • ベシル酸アムロジピン製剤を用いた簡易懸濁法適用時における溶出能, OGATA FUMIHIKO, HAYASHI TOMONORI, NISHIURA SAORI, MATSUOKA HIROSHI, TACHIBANA SADANOBU, KAKEHI KAZUAKI, KAWASAKI NAOHITO, 日本薬学会年会要旨集, 132nd, 3, 264,   2012 03 05 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201202226092323701
  • Development of 1GHz High Gain 2-Stage Amplifier with Excellent Gain Flatness, NAKATANI Keigo, KAWASAKI Naoto, HOTTA Masayuki, SAWAHARA Yuichi, ISHIZAKI Toshio, IEICE technical report. Microwaves, 111, 458, 23, 26,   2012 02 23 , http://ci.nii.ac.jp/naid/110009546155
    Summary:To realize an excellent gain flatness for 2-stage high-gain amplifier, a circuit configuration, which can achieve both high-gain and stable performance, is studied. This time, an input/output damping circuit and a negative feedback circuit are introduced to stabilize the circuit. The effects on the frequency characteristics by the both circuits are investigated. Then, the amplifier is designed and fabricated based on the simulation results, where the both circuits are properly combined. As a result, the experimental amplifier are successfully demonstrated with an excellent performance, of which is fundamental gain of 40.9dB and in-band gain ripple of 0.2dB for 20% fractional bandwidth.
  • 1GHz 2-Stage Compact Amplifier Stabilized by Feedback Circuit, SAWAHARA Yuichi, HOTTA Masayuki, KAWASAKI Naoto, NAKATANI Keigo, ISHIZAKI Toshio, IEICE technical report. Microwaves, 111, 458, 31, 34,   2012 02 23 , http://ci.nii.ac.jp/naid/110009546157
    Summary:We designed a two-stage microwave amplifier stabilized by negative feedback through air-core coil. The air-core coil is a hand-made one and the effects of its self-resonance on the amplifier performance are investigated. A two-stage amplifier is designed and fabricated. Very small chip components, except for the air-core coil, are used for fabricating the amplifier. The size of the amplifier is 22mm by 35mm. Thus, drastic miniaturization is achieved.
  • Results and problems on health enhancement program in Kinki University Antiaging Center, 田中 ひかる, 松浪 登久馬, 岡田 龍司, 大島 寛, 熊本 和正, 高島 規郎, 佐川 和則, 直井 愛里, 成川 輝明, 村上 哲男, 川崎 直人, 掛樋 一晃, 近畿大学教養・外国語教育センター紀要. 一般教養編, 2, 1, 43, 50,   2012 , http://ci.nii.ac.jp/naid/120005729771
  • Study on recovery and recycling of platinum by calcined gibbsite, Inoue Kenji, Ogata Fumihiko, Kawasaki Naohito, Proceedings of the Annual Conference of Japan Society of Material Cycles and Waste Management, 23, 0,   2012 , http://ci.nii.ac.jp/naid/130005453443
    Summary:Platinum is used in ornaments, catalytic agent, and medical chemical, have been much in demand recently, in spite of the limited natural resource in the crust. White cisplatin, anticancer agent, contains platinum in structure. That becomes unaltered substance and metabolites, they have been discharged into water environmental. Gibbsite, aluminum hydroxide, is a very cheep adsorbent and has an anion exchange ability. Therefore, the cisplatin which contains platinum, will be recovered by calcined gibbsite. In this study, a calcined gibbsite at 400 (GB400) was used for adsorbent, the adsorption properties of H<sub>2</sub>PtCl<sub>6</sub> and cisplatin by GB400 were investigated based on the amount adsorbed and the phyco-chemical properties of GB400. In H<sub>2</sub>PtCl<sub>6 </sub>and cisplatin solutions, adsorption ability of Pt(IV) by GB400 at pH 5 and pH8, respectively, was the greatest. The amount adsorbed of cisplatin was smaller than that of H<sub>2</sub>PtCl<sub>6.</sub> Platinum is adsorbed as [PtCl<sub>5</sub>(OH)]<sup>2- </sup>onto GB400, because H<sub>2</sub>PtCl<sub>6</sub> is present as that in the solution of pH5. These results indicated that GB400 may be utilized for the recovery of platinum.
  • Recovery Technique for Phosphate Using Granular Gibbsite with Binder, OGATA Fumihiko, TOMINAGA Hisato, KANGAWA Moe, INOUE Kenji, KAWASAKI Naohito, Journal of Water and Environment Technology, 10, 2, 177, 191,   2012 , http://ci.nii.ac.jp/naid/130001907906
    Summary:In the present study, granular gibbsite with vinyl acetate (20%, G-GB20) was used for the removal of phosphate from artificial sewage. The amount of phosphate adsorbed was studied using batch techniques. The effect of different parameters, namely contact time, initial concentration, solution pH, and temperature were investigated. The adsorption kinetics data were best described by the pseudo-second-order rate equation and equilibrium was achieved after 12 h. The Langmuir and Freundlich equations for describing adsorption equilibrium were applied to the experimental data. The correlation coefficients of the Langmuir and Freundlich equations were 0.960 - 0.996 and 0.960 - 0.995, respectively. A number of thermodynamic parameters, namely free energy, enthalpy, and entropy change for the adsorption of phosphate were evaluated and it was found that the reaction was spontaneous and endothermic in nature. Adsorbent (G-GB20) was used for repeated adsorption and desorption of phosphate and a breakthrough curve was obtained. It was shown that G-GB20 could be used three times for repetitive adsorption and desorption of phosphate. Results suggest that the prepared G-GB20 has great potential in the remediation of water contaminated by phosphate.
  • Adsorption Capacity of Dye in the Presence of Dying Assistant Auxiliaries by Carbonaceous Material Produced from Cotton, OGATA Fumihiko, TOMINAGA Hisato, KANGAWA Moe, INOUE Kenji, KAWASAKI Naohito, 表面科学 : hyomen kagaku = Journal of the Surface Science Society of Japan, 32, 12, 804, 808,   2011 12 10 , 10.1380/jsssj.32.804, http://ci.nii.ac.jp/naid/10030442812
  • 特定健診・特定保健指導の有効性と腹囲の測定誤差に関する評価, KAWASAKI NAOTO, OGATA FUMIHIKO, 日本公衆衛生学会総会抄録集, 70th, 187, 187,   2011 10 15 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201102203426021984
  • Properties of carbonaceous material produced from cotton and its dye adsorption capabilities, Fumihiko Ogata, Hisato Tominaga, Moe Kangawa, Kenji Inoue, Naohito Kawasaki, e-Journal of Surface Science and Nanotechnology, 9, 380, 385,   2011 10 15 , 10.1380/ejssnt.2011.380, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=80054737039&origin=inward
    Summary:In this study, methylene blue (MB), orange II (ORII), and indigo carmine (IC) were used as adsorbates. Untreated (CT) and treated cotton (CT400, CT600, CT800, and CT1000) were prepared from waste cotton, and their respective physical (i.e., specific surface area, pore volume, and mean pore diameter) and chemical properties (i.e., yield percentage, base consumption, and amount of pH solution added to the adsorbent) were investigated. Scanning electron microscope images of CT, the adsorption rate, and the adsorption isotherm were also analyzed. The specific surface area, pore volume, and mean pore diameter of CT1000 was greater than that of other CT varieties, indicating that the pores on the CT surface were generated by carbonization. Additionally, yield percentage and base consumption decreased because of carbonization. Equilibrium adsorption (i.e., MB, ORII, and IC) was reached within 12 h. The experimental data were fitted to a pseudo-second-order model, suggesting that the adsorption might be a chemisorption process, for which the correlation coefficient, R, equals 1.000. The amount of dye adsorbed onto CT1000 was as follows: IC (290 mg/g) > MB (446 mg/g) ∼ ORII (452 mg/g). These experimental data were fitted to the Freundlich equation. The present study implies that the adsorbent for dye removal can be produced from waste cotton and that it is useful for the purification of dye solution systems. © 2011 The Surface Science Society of Japan.
  • 小麦ふすまへのカドミウムおよび鉛イオンの吸着機構解明のための酵素処理, KANGAWA MOE, OGATA FUMIHIKO, TOMINAGA HISATO, INOUE KENJI, KAWASAKI NAOHITO, 衛生薬学・環境トキシコロジー講演要旨集, 2011, 185,   2011 10 05 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201202280279607970
  • 琵琶湖・淀川水系域の水質調査とリンの連続回収技術に関する研究, INOUE KENJI, OGATA FUMIHIKO, TOMINAGA HISATO, KANGAWA MOE, KAWASAKI NAOHITO, 衛生薬学・環境トキシコロジー講演要旨集, 2011, 182,   2011 10 05 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201202291204824438
  • Removal of Nitrate Ion or Nitrite Ion onto Carbonaceous Material Produced from Coffee Grounds by Ion Exchange, OGATA Fumihiko, TOMINAGA Hisato, YABUTANI Hitoshi, KAWASAKI Naohito, Journal of the Surface Science Society of Japan, 32, 7, 461, 466,   2011 07 10 , 10.1380/jsssj.32.461, http://ci.nii.ac.jp/naid/10029411087
  • 大学生の肥満と朝食欠食およびやせ志向との関連性に関する研究, KAWASAKI NAOTO, TOMINAGA HISATO, OGATA FUMIHIKO, SAGAWA KAZUNORI, KINOSHITA MITSUHIRO, KAKEHI KAZUAKI, 日本薬学会年会要旨集, 131st, 3, 249, 249,   2011 03 05 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201102259934003938
  • 大学生の朝食欠食と体格誤認に関する実態調査, TOMINAGA HISAHITO, OGATA FUMIHIKO, SAGAWA KAZUNORI, KINOSHITA MITSUHIRO, KAKEHI KAZUAKI, KAWASAKI NAOTO, 日本薬学会年会要旨集, 131st, 3, 222, 222,   2011 03 05 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201102278918671704
  • 琵琶湖における造粒ベーマイトを用いたリン酸吸着能, OGATA FUMIHIKO, KABAYAMA MINEAKI, WADA KEIKO, TOMINAGA HISAHITO, YABUTANI HITOSHI, KAWASAKI NAOTO, 日本薬学会年会要旨集, 131st, 3, 261,   2011 03 05 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201102265203178992
  • 有機性廃棄物の炭素材料への変換による循環型社会構築, KAWASAKI NAOHITO, OGATA FUMIHIKO, TOMINAGA HISAHITO, YABUTANI HITOSHI, エネルギーシステム・経済・環境コンファレンス講演論文集(CD-ROM), 27th, ROMBUNNO.4-2,   2011 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201102293188039720
  • Adsorption Capacity of Dye in the Presence of Dying Assistant Auxiliaries by Carbonaceous Material Produced from Cotton, OGATA Fumihiko, TOMINAGA Hisato, KANGAWA Moe, INOUE Kenji, KAWASAKI Naohito, Hyomen Kagaku, 32, 12, 804, 808,   2011 , http://ci.nii.ac.jp/naid/130004486630
    Summary:In this study, carbonaceous material was prepared from waste cotton (CT1000). Yield, base consumption, pH, specific surface area, pore volume, and mean pore diameter of CT1000 were investigated. Specific surface area and pore volume of CT1000 was greater than that of CT (virgin waste cotton). Kayacryl Yellow (KY: yellow dye) was used for adsorbate. The equilibrium adsorption was reached within 48 h. The adsorption rate data was fitted to the pseudo-second-order kinetic equation, which indicated that reaction rate was in proportion to the square of adsorbate concentration in aqueous solution systems. Moreover, the adsorption isotherm data was fitted to the Freundlich equation. Amount of KY adsorbed onto CT1000 in the presence of dye assistant auxiliaries was similar trend to that onto CT1000 in the absence of dye assistant auxiliaries. These results showed that CT1000 was useful for purification of wastewater containing dyestuffs.
  • Removal of Nitrate Ion or Nitrite Ion onto Carbonaceous Material Produced from Coffee Grounds by Ion Exchange, OGATA Fumihiko, TOMINAGA Hisato, YABUTANI Hitoshi, KAWASAKI Naohito, Hyomen Kagaku, 32, 7, 461, 466,   2011 , http://ci.nii.ac.jp/naid/130004486680
    Summary:In this study, carbonaceous material was prepared from coffee grounds as follows: coffee grounds were treated with 1 mol/L calcium chloride solution, and calcined at 600, 800, and 1000<SUP>o</Sup>C (CG600, CG800, and CG1000). Subsequently, CGs were treated with 6 mol/L hydrochloric acid solution. Amount of nitrate ion or nitrite ion adsorbed was in the order CG1000 < CG800 < CG600, which indicated that amount adsorbed depended on properties of CG surface (specific surface area and pore volume). The adsorption mechanism of nitrate ion or nitrite ion was ion exchange (1:1) present on the surface of CG600. The adsorption isotherm date were fitted to the Freundlich and Langmuir equations. In binary solution, nitrate ion and nitrite ion were competitive adsorption. CG600 was applied for tap water with a column. Condition 3 (S.V.: 4.3 l/hr, L.V.: 0.4 m/hr) was the most suitable for adsorption of nitrate ion.
  • Development of the Treatment Technology for Dye Removal from Aqueous Solution Using Activated Carbon Treatment and Ozone Oxidation, OGATA Fumihiko, TOMINAGA Hisato, YABUTANI Hitoshi, KAWASAKI Naohito, Journal of Water and Environment Technology, 9, 3, 297, 309,   2011 , http://ci.nii.ac.jp/naid/130001190405
    Summary:Activated carbon treatment and ozone oxidation were used for decolorization or total organic carbon (TOC) removal from an aqueous solution. Acid, neutral, and basic activated carbon (A-AC, N-AC, and B-AC) were prepared with particle sizes of 44 - 297 &mu;m (S), 297 - 500 &mu;m (M), and 500 - 840 &mu;m (L), respectively. Methylene blue (MB) and orange II (ORII) were used as adsorbates, and the amount of MB or ORII adsorbed onto AC depended on the specific surface area of the AC. The adsorption data were fitted to the Freundlich and Langmuir equations, which suggested that the mechanism by which dye is adsorbed onto AC is that of monomolecular adsorption onto a heterogeneous surface. After ozone treatment, the MB and ORII structures were degraded and decolorized. However, TOC was not significantly reduced because the dye structure was broken down by ozone oxidation, which generated low-molecular-weight molecules but did not remove them. Activated carbon treatment after ozone oxidation was very effective for dye and TOC removal. This treatment enhanced the TOC removal by up to 20 - 30% from that achieved solely by ozone treatment.
  • A Trial of the Integrated Cross-field Pharmaceutical Education in the First Year of Faculty of Pharmacy, Tomohisa Yasuhara, Naohito Kawasaki, Hideki Yagi, Eiji Itoh, Atsushi Kawase, Toru Otori, Tetsuyuki Wada, Kenji Matsuyama, Masahiro Iwaki, YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 130, 12, 1647, 1653,   2010 12 , http://ci.nii.ac.jp/naid/130000451722
    Summary:The six-year pharmacist education course has begun, and now first-year students receive clinical training. Interdisciplinary problem-solving capabilities covering chemistry, biology, molecular biology, pharmacology, pathology, and pharmacokinetics are necessary for new pharmacists. However, the conventional pharmaceutical science education was so separate from other fields that education for interdisciplinary cooperative capability was insufficient. This was especially true of elemental science courses, because they are not directly connected with clinical knowledge, and there is a problem of low student interest in those courses. As a result, students acquired only recall-level knowledge in clinical courses and their problem-solving capabilities in clinical treatment and drug development deteriorated. Therefore we offered a trial lecture aimed to help students recognize the important relationship between elemental science courses and clinical courses and increase their motivation to enroll in these courses. Specifically, the trial lecture covered cancer therapy, in reference to mechanisms of carcinogenesis, epidemiology, physiology of cancer, anticancer drugs with explanations of the mechanism of action of carcinogens, anticancer drugs, and molecular-targeted drugs from the viewpoints of organic chemistry and biochemistry by a specialized teacher. This paper reports on this experimental lecture with evaluations from students.
  • タイと日本の大学生における健康意識と生活習慣との関連性, 川崎 直人, 緒方 文彦, ブラパダジャ・シリポーン, 日本公衆衛生学会総会抄録集, 69回, 566, 566,   2010 10
  • 吸着法による廃食用油のリサイクルに関する研究, OGATA FUMIHIKO, AOYAMA HIDEYUKI, KOSEN TOMOHIDE, TANIWAKI TAKANORI, KAWASAKI NAOTO, 日本油化学会年会講演要旨集, 49th, 284,   2010 09 15 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201002292643298728
  • 大学生における睡眠習慣と身体的・精神的状態との関連性, OGATA FUMIHIKO, TOMINAGA HISATO, SAGAWA KAZUNORI, KINOSHITA MITSUHIRO, KAKEHI KAZUAKI, KAWASAKI NAOHITO, 衛生薬学・環境トキシコロジー講演要旨集, 2010, 216,   2010 08 10 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201002259196104719
  • 大学生の食習慣および体格評価の誤認に関する調査, TOMINAGA HISATO, OGATA FUMIHIKO, SAGAWA KAZUNORI, KINOSHITA MITSUHIRO, KAKEHI KAZUAKI, KAWASAKI NAOHITO, 衛生薬学・環境トキシコロジー講演要旨集, 2010, 217,   2010 08 10 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201002263465707562
  • コーヒー豆かす由来炭素材料による飲料水中におけるアニオンの吸着性能, YABUTANI HITOSHI, OGATA FUMIHIKO, TOMINAGA HISATO, KAWASAKI NAOHITO, 衛生薬学・環境トキシコロジー講演要旨集, 2010, 158,   2010 08 10 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201002265405052993
  • 有機性副産物を用いた炭素材料の創製とアンモニアの脱臭, KAWASAKI NAOTO, OGATA FUMIHIKO, TOMINAGA HISAHITO, 日本臨床環境医学会学術集会プログラム・抄録集, 19th, 31,   2010 07 01 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201002241068189497
  • Practical safety of using essential medicines and their market products in Thailand, Siriporn Burapadaja, Naohito Kawasaki, Suporn Charumanee, International Journal of Risk and Safety in Medicine, 22, 17, 25,   2010 03 24 , 10.3233/JRS-2010-0488, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=77949553362&origin=inward
    Summary:Safety is one of the very important elements of medicines, especially in daily practice. It is expected that the medicines listed by the Thai Essential Medicine Lists (EML) and their market products registered by the Thai Food and Drug Administration (FDA) should be comparable with respect to practical safety. The objective was to investigate if there are differences in practical safety between anti-infective essential medicines and their products assigned by the two authorities in Thailand. Data were based on Thai EML, Thai FDA registration, and Thailand Index of Medical Specialities 2008. Results showed that Thai EML and Thai FDA divided anti-infective items (n = 101) and their products into groups varying in practical safety. Two thirds of the items and their products were comparable with respect to practical safety, but one third of them were not. The products of the latter were defined as having a lower practical safety compared to their corresponding items. This study has demonstrated that there are differences in practical safety between several essential medicines and their products. Consistent practical safety is very necessary for safe use of anti-infective products. Thus, there should be deliberations between the two authorities to reconsider the practical safety of these items and their products. © 2010 - IOS Press and the authors. All rights reserved.
  • 琵琶湖における水質調査および造粒GBを用いた水質浄化に関する研究, OGATA FUMIHIKO, KABAYAMA MINEAKI, WADA KEIKO, KUMAGAI YOSHIYA, KAKEHI KAZUAKI, KAWASAKI NAOTO, 日本水環境学会年会講演集, 44th, 567,   2010 03 15 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201002280883899569
  • 簡易懸濁法におけるベシル酸アムロジピンを主成分とする先発品および後発品の溶出量の比較検討, HAYASHI TOMONORI, OGATA FUMIHIKO, KAWASAKI NAOTO, NISHIURA SAORI, MATSUOKA HIROSHI, TACHIBANA SADANOBU, KAKEHI KAZUAKI, 日本薬学会年会要旨集, 130th, 4, 227, 227,   2010 03 05 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201002234287968608
  • 塩化カルシウム処理したコーヒー豆かす由来炭素材料によるフッ素の除去, YABUTANI HITOSHI, OGATA FUMIHIKO, TOMINAGA HISAHITO, YAMAGUCHI ISAO, KAWASAKI NAOTO, 日本薬学会年会要旨集, 130th, 3, 232,   2010 03 05 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201002233674465308
  • 繊維産業における繊維由来炭素材料による合成染料の除去, YAMASHITA YUJI, YAMAGUCHI ISAO, OGATA FUMIHIKO, TOMINAGA HISAHITO, YABUTANI HITOSHI, KAWASAKI NAOTO, 日本薬学会年会要旨集, 130th, 3, 232,   2010 03 05 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201002284629942433
  • 食品廃棄物の炭化による循環型社会の形成, KAWASAKI NAOHITO, OGATA FUMIHIKO, エネルギーシステム・経済・環境コンファレンス講演論文集(CD-ROM), 26th, ROMBUNNO.16-1,   2010 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201002216396525963
  • Removal of NO3--N and NO2--N with Coffee Grounds by Ion Exchange, Fumihiko Ogata, Hitoshi Yabutani, Hisato Tominaga, Isao Yamaguchi, Naohito Kawasaki, KAGAKU KOGAKU RONBUNSHU, 36, 4, 293, 298,   2010 , 10.1252/kakoronbunshu.36.293, http://ci.nii.ac.jp/naid/10027040838
    Summary:To investigate the recycling of coffee grounds (CGs), the surfaces of CGs were modified with CaCl2 solution, and the adsorption mechanism of NO3--N and NO2--N on these surfaces was evaluated. Maximun adsorption of NO3--N and NO2--N was observed with CGs carbonized at 600 degrees C (CG600), and the amounts adsorbed increased with temperature, at the time of adsorption, reaching equilibrium after 24 h. The amount of chloride ions eluted from CG600 increased with the amount of NO3--N and NO2--N adsorbed. The adsorption isotherms of NO3--N and NO2--N were fitted by the Freundlich and the Langmuir equations. These results indicated that NO3--N and NO2--N were adsorbed onto CG600 by ion exchange. CGs treated with CaCl2 solution can be utilized for the removal of NO3--N and NO2--N from drinking water.
  • Amount of Amlodipine Besilate Released from Tablets (Originator and Generic Drugs) in Simple Suspension Method, Ogata Fumihiko, Kawasaki Naohito, Hayashi Tomonori, Nishiura Saori, Matsuoka Hiroshi, Tachibana Sadanobu, Kakehi Kazuaki, Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences), 36, 12, 874, 879,   2010 , http://ci.nii.ac.jp/naid/130004894750
    Summary:In the present study,we examined whether distilled water or tap water affects the release of the major component from the tablet in the simple suspension method.We first analyzed hospital tap water for the presence of 22 different elements and 11 of them (B,Na,Mg,Ca,Ni,Fe,Cu,Zn,Ba,Mn and Cd) were detected.However,the concentrations of all these elements were below the limits prescribed by the water quality standards for drinking water specified in the Waterworks Law of Japan.We then studied the release of amlodipine besilate from the originator product containing it as the active ingredient and 5 generic versions using the simple suspension method.The amlodipine contents of the originator product and generics were 98.2-101.7%,within the range specified in the Japanese Pharmacopoeia.After suspending in distilled water for 30 and 120 min,the amounts of amlodipine released from the originator drug were 15 and 38%,respectively.Those for generics at 30 and 120 min were similar to the originator except for one generic which was designed to release the active ingredient in the mouth.In conclusion,for the simple suspension method,the amounts of amlodipine released from originator drug with time into water were similar to those for generics.
  • Adsorption Rate of Dyes onto Carbonaceous Materials Produced from Waste Fibers, OGATA Fumihiko, KAWASAKI Naohito, YAMAGUCHI Isao, TOMINAGA Hisato, Journal of the Surface Science Society of Japan, 30, 12, 680, 687,   2009 12 10 , 10.1380/jsssj.30.680, http://ci.nii.ac.jp/naid/10026319064
  • 造粒ギブサイトによる3価ヒ素および6価クロムの吸着能, OGATA FUMIHIKO, KABAYAMA MINEAKI, TOMINAGA HISATO, YAMAGUCHI ISAO, YABUTANI HITOSHI, KAWASAKI NAOTO, 衛生薬学・環境トキシコロジー講演要旨集, 2009, 324,   2009 10 02 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=200902232753042032
  • 無機態窒素除去のための塩化カルシウムによる炭素材料表面処理, YABUTANI HITOSHI, OGATA FUMIHIKO, TOMINAGA HISATO, YAMAGUCHI ISAO, KAWASAKI NAOHITO, 衛生薬学・環境トキシコロジー講演要旨集, 2009, 322,   2009 10 02 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=200902235593780081
  • 廃繊維由来炭素材料を用いた繊維事業所からの染料排水処理, YAMAGUCHI ISAO, OGATA FUMIHIKO, TOMINAGA HISATO, YABUTANI HITOSHI, KAWASAKI NAOTO, 衛生薬学・環境トキシコロジー講演要旨集, 2009, 325,   2009 10 02 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=200902251250371661
  • 希少金属であるバナジウムおよびモリブデンの造粒GBによる回収, TOMINAGA HISATO, OGATA FUMIHIKO, YAMAGUCHI ISAO, YABUTANI HITOSHI, KAWASAKI NAOHITO, 衛生薬学・環境トキシコロジー講演要旨集, 2009, 168,   2009 10 02 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=200902261526748530
  • Factors associated with the market availability of systemic anti-infective products in Thailand (no. 743), Siriporn Burapadaja, Naohito Kawasaki, Suporn Charumanee, Ornanong Kittipongpatana, Fumihiko Ogata, Journal of Public Health, 17, 251, 256,   2009 08 01 , 10.1007/s10389-009-0247-8, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=68249160898&origin=inward
    Summary:Background: Despite the fact that the market availability of medicines has been recognized as one of the most important components in the health-care system, its association with other factors is still in doubt. Objective: This study aimed at determining the factors associated with the number of trade names and products of systemic anti-infective medicines available for the market in Thailand. Methods: A cross-sectional study on the data from the Thai National List of Essential Medicines (Thai EML) 2008 and Thailand Index of Medical Specialties 2008 was undertaken. Results: Results showed a total of 702 trade names and 1,262 products from 137 generic drugs. Half of the products belonged to the classes of beta-lactam antibacterials (39%) and quinolone antibacterials (11.3%). The significant factors found were dosage forms of medicines, manufacturer types and category. The generic drugs that were prepared in more than one dosage form, produced by local manufacturers and categorized as essential medicines (EMs) would have a greater number of trade names and products than those done in one dosage form by foreign manufacturers and as non-EMs. Conclusion: There are at least three factors associated with the number of trade names and products of systemic anti-infective medicines, which include dosage forms of medicines, manufacturer types and EM category. These factors have involved the technical issue, private sector and Thai EML. One suggestion from this finding is to use the Thai EML as a means to control the market availability of systemic anti-infective products in the country. © 2009 Springer-Verlag.
  • 日本およびタイの大学生における食習慣,運動習慣との関連性, KAWASAKI NAOHITO, OGATA FUMIHIKO, BURAPADAJA SIRIPORN, LOETKHAM CHAOWALIT, 日本生理人類学会誌, 14, 140, 141,   2009 06 05 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201102275402794592
  • 琵琶湖におけるアルミニウム系化合物を用いたリン酸回収に関する研究, OGATA FUMIHIKO, KABAYAMA MINEAKI, WADA KEIKO, KUNO MAKOTO, KAKEHI KAZUAKI, KAWASAKI NAOHITO, 日本水環境学会年会講演集, 43rd, 502,   2009 03 16 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=200902251911853951
  • 簡易懸濁法におけるベシル酸アムロジピンを主成分とする先発品および後発品と金属イオンとの相互作用, HAYASHI TOMONORI, OGATA FUMIHIKO, KAWASAKI NAOTO, NISHIURA SAORI, MATSUOKA HIROSHI, TACHIBANA SADANOBU, KAKEHI KAZUAKI, 日本薬学会年会要旨集, 129th, 4, 244, 244,   2009 03 05 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=200902230776577399
  • 廃繊維由来炭素材料による染料の除去, YAMAGUCHI ISAO, OGATA FUMIHIKO, TOMINAGA HISATO, KAWASAKI NAOTO, 日本薬学会年会要旨集, 129th, 3, 233,   2009 03 05 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=200902259656314970
  • 火力発電所におけるフライアッシュからのレアメタルの回収, TOMINAGA HISATO, OGATA FUMIHIKO, YAMAGUCHI ISAO, SHODA TOMOKO, KAWASAKI NAOTO, 日本薬学会年会要旨集, 129th, 3, 232,   2009 03 05 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=200902282094165684
  • 繊維事業所内における染色排水処理システムの構築, KAWASAKI NAOHITO, OGATA FUMIHIKO, OMORI HIDEKI, TASAKI KEITA, エネルギー・資源学会研究発表会講演論文集(CD-ROM), 28th, ROMBUNNO.18-1,   2009 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=200902220579319722
  • Adsorption Ability of Arsenic (III) and Chromium (VI) onto Granular GB, Fumihiko Ogata, Naohito Kawasaki, Mineaki Kabayama, Kazuaki Kakehi, KAGAKU KOGAKU RONBUNSHU, 35, 1, 42, 46,   2009 , 10.1252/kakoronbunshu.35.42, http://ci.nii.ac.jp/naid/10025306882
    Summary:Arsenic (III) and chromium (VI) are known to be harmful for human health. In this study, gibbsite (GB) was granulated using ethyl cellulose or alumina sol 520 for the removal of arsenic (III) and chromium (VI). Two kinds of granular GBs had the ability to adsorb arsenic (III) and chromium (VI), with arsenic (III) being adsorbed in greater amount. Use of ethyl cellulose to prepare granular GB may not be economically suitable, because the production process is complex and requires the use of solvent. The amount of arsenic (III) and chromium (VI) adsorbed onto GB was slightly decreased by the granulation. The amount of arsenic (III) adsorbed onto granular GB in a binary solution system was greater than that in single solution system, while the amount of chromium (VI) adsorbed was similar in both systems. The adsorption mechanism of arsenic (III) and chromium (VI) is thought to dependent on the affinity between the metals and the surface or porosity of granular GB. The prepared GB could be utilized for removal of arsenic (III) or chromium (VI) in an aqueous environment.
  • Adsorption Rate of Dyes onto Carbonaceous Materials Produced from Waste Fibers, OGATA Fumihiko, KAWASAKI Naohito, YAMAGUCHI Isao, TOMINAGA Hisato, Hyomen Kagaku, 30, 12, 680, 687,   2009 , http://ci.nii.ac.jp/naid/130004486526
    Summary:Waste fibers are produced by textile industry and colored wastewater is released, the people hope to development the useful reused methods of it. And the release of colored wastewater induced aesthetically unpleasant, produced the carcinogen from chlorination. In this study, we produced the carbonaceous materials produced from waste fibers, developed the amount adsorbed and the adsorption rate of dyes. As a results, the specific surface area of waste fibers is increasing with increasing the carbonized temperatures. Amount adsorbed of each dyes onto carbonaceous materials produced from waste fibers at 1000<SUP>o</SUP>C is highest. In waste fibers, amount adsorbed of each dyes onto 2 h heating-2 h maintaining carbonaceous materials produced from waste fibers is increasing colored wool < untreated wool < colored wool-polyester < polyester, it showed the waste fiber from polyester is more suitable for adsorption than that of wool. Carbonaceous materials produced from waste fibers at 1000<SUP>o</SUP>C could treat to adsorbed the Methylene blue and Orange II in 20 min from the adsorption beginning. The carbonaceous materials produced from waste fiber would be utilized for adsorbates to remove dyes.
  • タイ及び日本の薬学部大学生の身体的,精神的状態に関する調査, KAWASAKI NAOTO, OGATA FUMIHIKO, 日本公衆衛生学会総会抄録集, 67th, 655, 655,   2008 10 15 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=200902215171895314
  • 水酸化アルミニウムゲルによるリン酸イオンの吸・脱着能, OGATA FUMIHIKO, KAWASAKI NAOTO, KAKEHI KAZUAKI, KABAYAMA MINEAKI, 化学工学会秋季大会研究発表講演要旨集(CD-ROM), 40th, U303,   2008 08 24 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=200902213448779004
  • Removal ability of copper and cadmium by biomass treated with enzymes, 緒方 文彦, 川崎 直人, 佐伯 美由紀, Journal of water and waste, 50, 5, 405, 411,   2008 05 , http://ci.nii.ac.jp/naid/40016036574
  • 簡易懸濁法に使用される薬剤と水道水中の金属イオンとの相互作用, HAYASHI TOMONORI, OGATA FUMIHIKO, KAWASAKI NAOTO, NISHIURA SAORI, MATSUOKA HIROSHI, TACHIBANA SADANOBU, KAKEHI KAZUAKI, 日本薬学会年会要旨集, 128th, 4, 189, 189,   2008 03 05 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=200902256966447415
  • 染料含有排水処理のための廃繊維由来炭素材料の創製, OGATA FUMIHIKO, KAWASAKI NAOHITO, KAKEHI KAZUAKI, TANADA SHIGENORI, 日本薬学会年会要旨集, 128th, 3, 152, 152,   2008 03 05 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=200902260985334963
  • Structural of Recycle System by Carbonization of Waste Fiber, KAWASAKI Naohito, OGATA Fumihiko, TANADA Seiki, エネルギーシステム・経済・環境コンファレンス講演論文集 = Proceedings of the ... Conference on Energy, Economy, and Environment, 24, 101, 102,   2008 01 30 , http://ci.nii.ac.jp/naid/10022534248
  • 染料の活性炭を同時併用したオゾン処理(OZAC)に関する研究, KAWASAKI NAOHITO, OGATA FUMIHIKO, YAMAGUCHI ISAO, TOMINAGA HISAHITO, 化学工学会九州支部大会研究発表講演要旨集, 2008, CD-ROM, D104,   2008 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=200902211389138170
  • Adsorption-desorption ability of phosphate by calcined aluminum hydroxide gel, Kawasaki Naohito, Ogata Fumihiko, Kabayama Mineaki, Abstract of annual meeting of the Surface Science of Japan, 28, 0, 131, 131,   2008 , http://ci.nii.ac.jp/naid/130004673923
    Summary:湖沼,海域におけるリン,窒素などの栄養塩類の増加は,富栄養化と言われ,アオコや赤潮という環境問題の原因となっている。また,有用な資源であるリンは,枯渇が懸念されており,リンを回収し,再資源化する技術が必要となる。今回,制酸剤として用いられている乾燥水酸化アルミニウムゲルを異なる温度で焼成し,その表面官能基とリン回収能との関連性について検討した。
  • シックハウス症候群防止を指向した生活環境中からのホルムアルデヒド除去, TANADA SHIGENORI, KAWASAKI NAOTO, OGATA FUMIHIKO, 日本公衆衛生学会総会抄録集, 66th, 651, 651,   2007 10 15 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=200902221872729150
  • 内分泌撹乱物質ノニルフェノールの廃棄物由来炭素材料による除去, KAWASAKI NAOTO, OGATA FUMIHIKO, TANADA SHIGENORI, 日本公衆衛生学会総会抄録集, 66th, 651, 651,   2007 10 15 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=200902273005474459
  • ギブサイト由来新規亜ヒ酸除去剤の開発, OGATA FUMIHIKO, KAWASAKI NAOTO, TAKAHASHI KOZO, KAKEHI KAZUAKI, TANADA SHIGENORI, 化学工学会秋季大会研究発表講演要旨集(CD-ROM), 39th, 0, O125, 275,   2007 08 13 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=200902229774584438
  • 3種のアルミニウム系化合物による6価クロムの吸着能, KAWASAKI NAOTO, OGATA FUMIHIKO, SAEKI MIYUKI, TANADA SHIGENORI, 化学工学会秋季大会研究発表講演要旨集(CD-ROM), 39th, O126,   2007 08 13 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=200902230104208310
  • 酵素処理植物バイオマスによるカドミウム・銅の吸着能, OGATA FUMIHIKO, KAWASAKI NAOHITO, TAKAHASHI KOZO, NAKAMURA TAKEO, TANADA SEIKI, 日本水環境学会年会講演集, 41st, 42,   2007 03 15 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=200902219819346953
  • リン循環型社会を目指した水酸化アルミニウムゲルによる新規吸着剤の開発, TAKAHASHI KOZO, KAWASAKI NAOHITO, OGATA FUMIHIKO, TANADA SEIKI, NAKAMURA TAKEO, 日本水環境学会年会講演集, 41st, 144,   2007 03 15 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=200902243683892256
  • タイの主要河川(チャオプラヤ川,ピン川)における水質調査, TANADA SHIGENORI, KAWASAKI NAOTO, OGATA FUMIHIKO, TAKAHASHI KOZO, NAKAMURA TAKEO, BURAPADAJA SIRIPORN, 日本薬学会年会要旨集, 127th, 2, 195, 195,   2007 03 05 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=200902282678360357
  • 簡易懸濁法に影響を及ぼす金属カチオンおよび一般細菌数の院内水質調査, HAYASHI TOMONORI, NISHIURA SAORI, MATSUOKA HIROSHI, TACHIBANA SADANOBU, KUBO SHUICHI, OGATA FUMIHIKO, KAWASAKI NAOTO, TANATA SHIGENORI, KAKEI KAZUAKI, 日本薬学会年会要旨集, 127th, 3, 223, 223,   2007 03 05 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=200902289020058147
  • りん酸回収における造粒水酸化セリウムの実用性, TAKAHASHI KOZO, KAWASAKI NAOTO, OGATA FUMIHIKO, NAKAMURA TAKEO, TANADA SHIGENORI, 日本薬学会年会要旨集, 127th, 2, 195,   2007 03 05 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=200902200146607218
  • Structural of Carbonaceous Circulation Society by Recycle of Organic Wastes, KAWASAKI Naohito, BUN-EI Ryoma, OGATA Fumihiko, NAKAMUTA Takeo, TANADA Seiki, エネルギーシステム・経済・環境コンファレンス講演論文集 = Proceedings of the ... Conference on Energy, Economy, and Environment, 23, 559, 560,   2007 01 25 , http://ci.nii.ac.jp/naid/10021972116
  • ギブサイトによる6価クロムイオンの吸着能, OGATA FUMIHIKO, KAWASAKI NAOTO, TAKAHASHI KOZO, SAEKI MIYUKI, TANADA SHIGENORI, 日本環境学会研究発表会予稿集, 33rd, 161, 164,   2007 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=200902224821269978
  • P-1 Relationship between States of Physical or Mental and Sleeping Habits among University Students in Thailand and Japan(Proceedings of the 56th Meeting of Japan Society of Physiological Anthropology) :, KAWASAKI Naohito, TANEI Sigeharu, BURAPADAJA Siriporn, LOETKHAM Chaowalit, OGATA Fumihiko, TANADA Seiki, Journal of physiological anthropology, 26, 6,   2007 , http://ci.nii.ac.jp/naid/110006474196
  • 水酸化アルミニウムゲルによる亜ヒ酸イオンの吸着能, OGATA FUMIHIKO, KAWASAKI NAOHITO, NAKAMURA TAKEO, TANADA SEIKI, 日本化学会西日本大会講演予稿集, 2006, 240,   2006 11 15 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=200902200189706406
  • 有機性廃棄物の種々の炭化法による調湿剤の開発, KAWASAKI NAOHITO, OGATA FUMIHIKO, NAKAMURA TAKEO, TANADA SEIKI, 日本化学会西日本大会講演予稿集, 2006, 241,   2006 11 15 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=200902268811937937
  • 酸処理植物バイオマスによるカドミウムおよび銅の除去能, OGATA FUMIHIKO, KAWASAKI NAOHITO, NAKAMURA TAKEO, TANADA SHIGEKI, 日本環境学会研究発表会予稿集, 32nd, 13, 16,   2006 06 10 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=200902230675839910
  • Structure transformation of gibbsite by calcination, Fumihiko Ogata, Naohito Kawasaki, Mineaki Kabayama, Takeo Nakamura, Seiki Tanada, e-Journal of Surface Science and Nanotechnology, 4, 267, 269,   2006 03 11 , 10.1380/ejssnt.2006.267, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=33644975364&origin=inward
    Summary:Gibbsite, which is aluminum oxide, was calcined in the temperature range from 200 to 1150°C, and the relation between the calcination temperature and various properties of gibbsite has been examined. It is speculated based on the results of TG-DTA experiment that the structure of gibbsite changed greatly at a calcination temperature of 282.7° C. Specific surface area of gibbsite kept on increasing as the calcination temperature is elevated up to 400° C, where it reached a maximum value. In the range where the calcination temperature is higher than 400° C, specific surface area, decreased as the temperature was elevated further. In addition, it became evident from the results of XRD measurement that in the calcination temperature range lower than 200° C, the crystal kept gibbsite structure, but it changed to the structure of aluminum oxide of transition type above 300° C. and that it changed further to the structure of stable aluminum oxide when the calcination temperature was elevated over 1000°C. From these results, it is verified that by making use of the fact that the structure of gibbsite changes greatly in the calcination temperature range from 300 to 400° C, a novel adsorbent having boehmite structure can be produced. © 2006 The Surface Science Society of Japan.
  • 焼成ベーマイトによる亜ヒ酸と六価クロムの除去, OGATA FUMIHIKO, KAWASAKI NAOTO, NAKAMURA TAKEO, TANADA SHIGENORI, KABAYAMA MINEAKI, 日本薬学会年会要旨集, 126th, 3, 160, 160,   2006 03 06 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=200902218441877932
  • 鉛イオン除去およびマグネシウムイオン溶出の両機能を有する高機能性吸着剤の開発, TANADA SEIKI, KAWASAKI NAOTO, NAKAMURA TAKEO, OGATA FUMIHIKO, 日本薬学会年会要旨集, 126th, 3, 191,   2006 03 06 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=200902217947990811
  • ベーマイトの表面水酸基とリン吸着能との関連性, KAWASAKI NAOTO, NAKAMURA TAKEO, OGATA FUMIHIKO, TANADA SEIKI, KABAYAMA MINEAKI, 日本薬学会年会要旨集, 126th, 3, 191,   2006 03 06 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=200902234403961941
  • Removal of Lead and Iron in Water by Waste Biomass, KAWASAKI Naohito, NAKAMUTA Takeo, TANADA Seiki, エネルギーシステム・経済・環境コンファレンス講演論文集 = Proceedings of the ... Conference on Energy, Economy, and Environment, 22, 511, 514,   2006 01 26 , http://ci.nii.ac.jp/naid/10021970757
  • 植物バイオマスによる飲料水中の鉄・鉛イオンの除去, OGATA FUMIHIKO, KAWASAKI NAOTO, NAKAMURA TAKEO, TANADA NARINORI, 農業環境工学関連学会合同大会講演要旨集(CD-ROM), 2006, W203,14NICHI,DAI5SESSHON,1,   2006 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=200902239071096615
  • コーヒー豆かすによるアンモニアの脱臭効果に関する基礎的研究, KAWASAKI NAOTO, NAKAMURA TAKEO, OGATA FUMIHIKO, TANADA NARINORI, 農業環境工学関連学会合同大会講演要旨集(CD-ROM), 2006, W203,14NICHI,DAI1SESSHON,3,   2006 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=200902252107334603
  • Preliminary Study on the Education Program of Information (2) Consideration about the information processing education in care worker training, Kawasaki Akihiro, Fujiwara Naohito, Journal of Ryukoku University, 467, 53, 75,   2006 01 , http://ci.nii.ac.jp/naid/110009553131
  • Water Treatment Technology Using Carbonaceous Materials Produced from Vegetable Biomass, Kawasaki Naohito, Bun-ei Ryoma, Ogata Fumihiko, Nakamura Takeo, Tanei Shigeharu, Tanada Seiki, Journal of Water and Environment Technology, 4, 1, 73, 82,   2006 , http://ci.nii.ac.jp/naid/130000099891
    Summary:This study investigated the adsorptive capacity for lead ions of wheat bran (WB), which is a vegetable biomass. The results show that in adsorption by WB, lead ions are competitive with calcium ions. Also, the ability of WB carbonized at 1000&deg;C, to remove lead ions, was higher than that by WB in the low concentration range. The amount of magnesium ions eluted from carbonized WB per unit mass was highest for WB carbonized at 800&deg;C, and was approximately 8 times the amount eluted from WB. Furthermore, the total viable bacteria count after 36 h of WB treatment at 15 - 35&deg;C was 7380 or more. However, the total viable bacteria count after 48h for carbonized WB was 20 - 280, suggesting the possible usage for treatment of drinking water. These results suggest that carbonized WB can be a new adsorbent, have the mineral release ability -- i.e. an adsorbent which removes lead ions which are harmful to people, and releases calcium ions and magnesium ions which are beneficial to people.
  • Indigo carmine removal by charcoal from rice bran as an agricultural by-product, T. Nakamura, N. Kawasaki, S. Tanada, T. Tamura, Y. Shimizu, Toxicological and Environmental Chemistry, 87, 321, 327,   2005 07 01 , 10.1080/02772240500126952, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=30344458477&origin=inward
    Summary:On the utilization of agricultural by-product, charcoal from rice bran was produced. The adsorption characteristics of indigo carmine onto charcoals from rice bran were investigated by the batch method. The yield and surface area of charcoal were decreased and increased with increase of carbonization temperature, respectively. The removal ratio of indigo carmine was high with the charcoal carbonized at higher temperature. In the relationship between the amount of indigo carmine adsorbed and the square root of elapsed time, a good linearity was recognized. The kinetic constant of adsorption removal for indigo carmine was rapid in the charcoal carbonized at higher temperature. The adsorption characteristics for indigo carmine removal by charcoal from rice bran were dominated by the value of their surface area. © 2005 Taylor & Francis.
  • Adsorption/desorption characteristics of phosphate ion onto calcined boehmite surface, Mineaki Kabayama, Naohito Kawasaki, Takeo Nakamura, Seiki Tanada, e-J. Surf. Sci. Nanotech., 3, 63, 69,   2005 02 20 , 10.1380/ejssnt.2005.63, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=18444382041&origin=inward
    Summary:Boehmite (aluminum oxyhydroxide, BE) selectively adsorbs phosphate ion. Recently, we studied the recovery efficiency of phosphate ion and the adsorption/desorption mechanism by calcining the BE surface in the temperature range of 200-1150°C. As a result, the amount of phosphate ion adsorbed/desorbed by BE at a calcining temperature of 400-700°C exhibited a higher value than the BE at other calcining temperatures, and the recovery efficiency of the phosphate ion was 90% or higher. On the other hand, the amount of phosphate ion adsorbed/desorbed onto BE at a calcining temperature of 1100°C or higher exhibited a lower value than the BE before calcining. Based on the phosphate ion adsorption/desorption behavior results, and the XRD and FT-IR results, it was determined that when the calcined BE is suspended in water, water molecules are dissociated, producing hydroxyl groups on the surface, and these hydroxyl groups exchange ions with the phosphate ion, thus the amount of phosphate adsorbed ion reaches a maximum. The phosphate ion adsorbed by BE was adsorbed by a sodium hydroxide solution, just like the BE before calcination. It became evident that by calcining BE, it is possible to obtain an adsorbent with a high phosphate ion recovery efficiency. © 2005 The Surface Science Society of Japan.
  • Abilities of Intensified Humidity-control-charcoal Produced from Wood Waste, NAKANISHI Akio, TAMAI Motoharu, TANADA Seiki, NAKAMURA Takeo, KAWASAKI Naohito, Journal of the Japan Society of Waste Management Experts, 14, 1, 13, 19,   2005 01 31 , 10.3985/jswme.16.13, http://ci.nii.ac.jp/naid/10013813045
  • Development of Water Treatment Technology by Vegetable Biomass, KAWASAKI Naohito, NAKAMUTA Takeo, TANADA Seiki, エネルギーシステム・経済・環境コンファレンス講演論文集 = Proceedings of the ... Conference on Energy, Economy, and Environment, 21, 137, 138,   2005 01 26 , http://ci.nii.ac.jp/naid/10021968798
  • 開発途上国における飲料水中の重金属イオン除去法, KAWASAKI NAOTO, OGATA FUMIHIKO, NAKAMURA NAOFUMI, NAKAMURA TAKEO, TANADA SHIGENORI, 日本環境学会研究発表会予稿集, 31st, 118, 119,   2005 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=200902279491885056
  • A Preliminary Study on the Education Program of Information Processing in Social Welfare Course of Junior College, Fujiwara Naohito, Kawasaki Akihiro, Journal of Ryukoku University, 465, 25, 39,   2005 01 , http://ci.nii.ac.jp/naid/110009555012
  • Abilities of Intensified Humidity-control-charcoal Produced from Wood Waste, Nakanishi Akio, Tamai Motoharu, Tanada Seiki, Nakamura Takeo, Kawasaki Naohito, Journal of the Japan Society of Waste Management Experts, 16, 1, 13, 19,   2005 , http://ci.nii.ac.jp/naid/130001758536
    Summary:Intensified humidity-control-charcoals (IHCCs) are produced from wood waste. IHCCs are intensified by two kinds of salt, sodium chloride and calcium chloride. Conventional charcoals have no high humidity control capacity; the absorption of steam into charcoals is particularly limited in the high humidity range (over 60% RH) . IHCCs are free from that limitation.<BR>Absorption of steam into IHCCs occurs in two phases, an adsorption phase and a reserve phase. The absorption phase is the process by which the salts attract steam from the atmosphere. The reserve phase is the process by which the charcoal retains that steam as water. Analyzing and improving IHCCs using this division of processes, the humidity control ability of IHCCs was increased to 1.2-4.0 times that of conventional charcoals. Moreover, IHCCs using calcium chloride have a higher humidity control ability than those using sodium chloride.<BR>Humidity-control materials require durability for their practical application. Silica gel has a higher humidity control ability than charcoals and IHCCs, but the durability of its absorption ability of steam is lower than that of other materials. Considering these characteristics together, IHCCs offer higher humidity control ability than regular charcoal and a higher durability of steam absorption than silica gel.
  • Adsorption of phosphate ions from sea water by use of surface-modified boehmite, KABAYAMA Mineaki, KAWASAKI Naohito, NAKAMURA Takeo, TOKIMOTO Toshimitsu, TANADA Seiki, J. Surface. Sci. Jpn., 25, 8, 499, 504,   2004 08 10 , 10.1380/jsssj.25.499, http://ci.nii.ac.jp/naid/10013444837
    Summary:In an attempt to develop materials to remove phosphorus that causes eutrophication or red tide, boehmite (aluminum oxide hydroxide) was surface-treated with sulfuric acid, nitric acid, hydrochloric acid, and sulfates, and the adsorption rates and adsorption isotherms of phosphate ions onto them were measured. The amount of phosphate ions adsorbed onto the boehmite, which was treated with sulfuric acid, was the greatest. This suggests that hydroxyl groups located in the boehmite are exchanged for sulfate groups by the sulfuric acid treatment. When boehmite was surface-treated with sulfuric acid of different concentrations, the amount of phosphate ions adsorbed increase with the increasing concentration of sulfuric acid. This result indicates that the adsorption of phosphate ions can be controlled by the amount of sulfate groups introduced in boehmite. The sulfate group of boehmite could also be introduced by an acidic sulfate solution treatment. When boehmite was treated with sulfuric acid, its capacity to adsorb a low concentration of phosphate ions from sea water increased to approximately 3 times that of the untreated boehmite. This suggests that the boehmite after the treatment of sulfuric acid or an acidic sulfate solution could be utilized for removing phosphate ions from sea water.
  • Carbonization of Coffee Grounds Surface by Microwave and Adsorption Behavior of Nitrite Nitrogen, KAWASAKI Naohito, TOKIMOTO Toshimitsu, NAKAMURA Takeo, SATOH Kiyomi, KABAYAMA Mineaki, TANADA Seiki, J. Surf. Sci. Soc. Jpn., 25, 7, 382, 386,   2004 07 10 , 10.1380/jsssj.25.382, http://ci.nii.ac.jp/naid/10013275178
    Summary:Recently, some harmful compounds and bacteria have been detected from tap water. Particularly, the nitrite nitrogen causes methemoglobinemia and cyanosis for infants. In this study, the surfaces of coffee grounds were carbonized by microwave and carbonaceous materials were produced. The specific surface area of the coffee grounds did not change by carbonization, while the base consumption decreased. Moreover, we estimated the extent of the adsorption of nitrite nitrogen onto the coffee grounds in terms of its removal from tap water. The adsorption mechanism of nitrite nitrogen onto coffee grounds would be monolayer adsorption, because the adsorption isotherms fitted to Freundlich or Langmuir equations. It is suggested that the adsorption of nitrite nitrogen onto coffee grounds is related to the phenolic hydroxyl and carboxyl groups. The coffee grounds thus can be utilized for the removal nitrite nitrogen from tap water.
  • Simple Analog Filter to Improve the Voice Articulation of Mobile Phones and PHS Under Noisy Environment, KOGA Jun-ichi, KAWASAKI Naoto, FUJII Shigekiyo, TAKAGI Hideyuki, The Transactions of the Institute of Electronics, Information and Communication Engineers. A, 87, 7, 881, 889,   2004 07 01 , http://ci.nii.ac.jp/naid/110003311837
    Summary:街頭雑音環境下における携帯電話・PHSの単音めいりょう度を改善するための簡易なアナログフィルタを設計し,評価を行う.小振幅の音声をより聞きやすくすることを設計方針とし,高域強調型の音声補正フィルタ,及び一定以上の振幅波形をカットするリミッタ,リミッタで生じた非線形ひずみを低減する低域通過型フィルタを組み合わせる.背景雑音の騒音レベルが70dB(A)及び80dB(A)の環境下で,24名の被験者による評価実験を行った結果,このフィルタを装着したPHSは,装着していない従来のPHSに比べ,単音めいりょう度を平均9%改善できることが明らかになった.
  • Accelerating effect of sodium chloride on mexiletine adsorption onto activated charcoal, T. Nakamura, Y. Oida, N. Kawasaki, S. Tanada, T. Tamura, Toxicol. Environ. Chem., 86, 205, 209,   2004 01 01 , 10.1080/02772240400007096, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=13444309506&origin=inward
    Summary:The effective use of activated charcoal as an oral adsorbent for primary treatment of acute poisoning was investigated in vitro by evaluating the characteristics of mexiletine, an anti-arrhythmic drug, adsorbed onto activated charcoal in the presence of sodium chloride solutions at various concentrations. The equilibrium amount of mexiletine adsorbed onto activated charcoal was increased by the addition of sodium chloride. In particular, there was a marked increase in the amount adsorbed from a solution of lower mexiletine concentration. The removal rate is another important factor in the evaluation of activated charcoal, and a rapid decrease of mexiletine concentration by the addition of sodium chloride was recognized. The acceleration of mexiletine adsorption onto activated charcoal by the addition of sodium chloride was due to the occurrence of salting-out. It could be concluded that the administration of activated charcoal suspended in saline solution was more effective in the primary treatment of acute poisoning by mexiletine overdose.
  • Paraquat and Diquat Removal by Chitosan Derivatives, 棚田 成紀, 中村 武夫, 川崎 直人, Bulletin of Pharmaceutical Research and Technology Institute, 13, 35, 41,   2004 , http://ci.nii.ac.jp/naid/40007000273
  • Adsorption and Desorption Properties of Phosphate Ion by Burning of Boehmite Surface, Kabayama Mineaki, Kawasaki Naohito, Nakamura Takeo, Tanada Seiki, Abstract of annual meeting of the Surface Science of Japan, 24, 0, 176, 176,   2004 , http://ci.nii.ac.jp/naid/130004673207
    Summary:これまでに,ベーマイトはリン酸イオンを選択的にかつ,高効率で吸着できることを明らかにしている。焼成今回,ベーマイト表面を200_-_1150℃の異なる温度で焼成し,リン酸イオンの吸・脱着特性について検討した。その結果,焼成によりX線回折の結果に変化が認められたが,表面構造(SEM画像)はほとんど影響されず,リン酸イオンを吸着後,焼成したべーマイトの方がアルカリにより再生しやすいことが明らかになった。
  • Water Sorption Behavior onto Carbonaceous Materials Produced from Bean Curd Lees, Kawasaki Naohito, Nakamura Takeo, Tanada Seiki, Kabayama Mineaki, Abstract of annual meeting of the Surface Science of Japan, 24, 0, 177, 177,   2004 , http://ci.nii.ac.jp/naid/130004673208
    Summary:調湿材としてオカラを適用するため,異なる温度でオカラを焼成し製した炭素材料への水分吸・脱着挙動について検討した。比表面積を測定した結果,焼成温度900℃の炭素材料において最も高値を示した。この結果より,焼成温度の上昇に伴い微細構造が発達するが,さらに高温にした場合,細孔が消失することが判った。市販の備長炭の調湿性能は22であり,オカラ由来炭素材料では最大で198となった。
  • Removal of Formaldehyde by Surface-modified Carbonaceous Materials, HIRATA Mizuho, KAWASAKI Naohito, NAKAMURA Takeo, BUNEI Ryoma, TANADA Seiki, Journal of the Surface Science Society of Japan, 24, 7, 417, 422,   2003 07 10 , 10.1380/jsssj.24.417, http://ci.nii.ac.jp/naid/10011228207
    Summary:Recently, formaldehyde liberated from wallpapers, furnitures and adhesive agents in new buildings and houses cause troubles in human health, and this is called the sick building symdrome. In this study, the carbonaceous materials are prepared from coffee grounds by microwave treatment or by surface-treatments with two different silane coupling agents. We estimated the removal efficiency of formaldehyde by such materials. The water contents of coffee grounds are larger than those of other wastes and thus they were easily carbonized. Both the amount of formaldehyde adsorbed onto the carbonaceous materials and the adsorption rate increased with increasing microwave treatment period, and increased with increasing concentration of silane coupling agents, because the numbers of amino groups on the carbonaceous materials increase. The carbonaceous materials prepared from the coffee grounds would be utilized for adsorbates to remove formaldehyde.
  • Moisture Control In-house by Carbon Produced from Woods Wastes-Iron System Constructional Materials, NAKANISHI Akio, TAMAI Motoharu, KAWASAKI Naohito, NAKAMURA Takeo, MATSUMOTO Kazuoki, TANADA Seiki, Journal of the Japan Society of Material Cycles and Waste Management, 14, 2, 69, 75,   2003 03 31 , 10.3985/jswme.14.69, http://ci.nii.ac.jp/naid/130001758135
    Summary:Recently, the recycling of organic by-products and wood wastes has become very important. The development of technology for recycling organic by-products needs to have sustainable development and be helpful to human life. In this study, the techniques for producing carbonaceous adsorbents from a wood waste and iron, and the application to humidity control in the house are described. The amount of water adsorbed onto carbon produced from woods wastes-iron system constructional materials was greater than that adsorbed onto the carbonaceous materials. The carbon produced from woods wastes-iron system constructional materials could be used repeatedly. These results indicated that the carbon produced from woods wastes-iron system constructional materials could be useful for the humidity control.
  • Inhibitory Effect of Sorbitol on Acetaminophen Adsorption by Activated Carbon, Tanada Seiki, Nakamura Takeo, Kawasaki Naohito, Bulletin of Pharmaceutical Research and Technology Institute, 11, 123, 130,   2003 03 05 , http://ci.nii.ac.jp/naid/110000970422
  • Relationship between Surface Polarity of Carbonaceous Materials and Removal Ability of Bisphenol A, ARAKI Mamiko, KAWASAKI Naohito, NAKAMURA Takeo, MATSUMOTO Kazuoki, TANADA Seiki, Journal of the Surface Science Society of Japan, 23, 7, 437, 442,   2002 07 10 , 10.1380/jsssj.23.437, http://ci.nii.ac.jp/naid/10009298907
  • Inhibitory effect of sorbitol on acetaminophen adsorption by activated carbon, 棚田 成紀, 中村 武夫, 川崎 直人, J. Environ. Sci. Health, A37(5) 905-912, 11, 123, 130,   2002 06 03 , 10.1081/ESE-120003596, http://ci.nii.ac.jp/naid/40005727645
    Summary:The effective use of activated carbon as oral adsorbent in the primary treatment of acute acetaminophen poisoning was studied. The adsorption characteristics of acetaminophen onto activated carbons in presence of sorbitol were investigated in vitro. Both the equilibrium amount adsorbed and the removal rate of acetaminophen onto activated carbon were decreased with the increase of sorbitol concentration in solutions. The sorbitol concentration independency of the inhibition to the acetaminophen adsorption was recognized. It was concluded that the addition of sorbitol to the suspension of activated carbon inhibited the acetaminophen adsorption by activated carbon.
  • IN VITRO Adsorption Characteristics of Acetaminophen with Activated Carbon Varying in Particle Size, Tanada Seiki, Nakamura Takeo, Kawasaki Noohito, Bulletin of Pharmaceutical Research and Technology Institute, 10, 55, 61,   2002 03 05 , http://ci.nii.ac.jp/naid/110000560600
  • Relationship between Surface Polarity of Carbonaceous Materials and Removal Ability of Bisphenol A., ARAKI Mamiko, KAWASAKI Naohito, NAKAMURA Takeo, MATSUMOTO Kazuoki, TANADA Seiki, Hyomen Kagaku, 23, 7, 437, 442,   2002 , http://ci.nii.ac.jp/naid/130004486090
    Summary:Today, over 70,000 synthetic organic chemicals are in general use. Some of the chemicals causes hormone imbalance. Those chemicals were called endocrine disruptors, for example bisphenol. In this study, the interaction between the surface of activated carbons and bisphenol A was estimated from the relation of the Freundlich constants and surface properties of activated carbons. The polarity groups of the activated carbon inhibited the adsorption of bisphenol A onto the pore of activated carbons the radius of which was from 7.5 to 20 &Aring;. Adsorption of bisphenol A onto the activated carbons depended upon both the polarity and pore structure of activated carbon. The reduced activated carbon was utilized for the removal of bisphenol A in water.
  • Comfortable Moisture Control in House by Carbon Produced from Woods By-products : Iron System Constructional Materials :, TANADA Seiki, NAKANISHI Akio, TAMAI Motoharu, KAWASAKI Naohito, NAKAMURA Takeo, Journal of physiological anthropology and applied human science, 21, 2,   2002 , http://ci.nii.ac.jp/naid/110002528595
  • IN VITRO Adsorption Characteristics of Acetaminophen with Activated Carbon Varying in Particle Size, 棚田 成紀, 中村 武夫, 川崎 直人, Bulletin of Pharmaceutical Research and Technology Institute, 81, 10, 55, 61,   2001 12 01 , 10.1080/02772240109359027, http://ci.nii.ac.jp/naid/40005013589
    Summary:Adsorption characteristics of acetaminophen onto activated carbon of varying particle sizes was investigated for emerging treatment of acute poisoning in vitro. No difference in the equilibrium amount of acetaminophen adsorbed among activated carbon of varying particle size was observed. This result could be explained by the properties of activated carbon. The smaller the particle size of activated carbon, the faster the acetaminophen was removed. It was assumed that the increase of contact surface area (external surface area) due to smaller particle size accelerated the adsorption of acetaminophen onto activated carbon.
  • Adsorption of hydrogen sulfide by zinc-containing activated carbon, T. Nakamura, N. Kawasaki, M. Hirata, Y. Oida, S. Tanada, Toxicological and Environmental Chemistry, 82, 93, 98,   2001 10 01 , http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0035480626&origin=inward
    Summary:Zinc-containing activated carbons (Zn-ACs) were prepared by impregnating raw activated carbon (R-AC) with zinc acetate solution. Then, the capacity of Zn-ACs to adsorb hydrogen sulfide as an offensive odor was evaluated. The values of physical properties of Zn-ACs were smaller than those of R-AC due to the filling pores of activated carbon by zinc acetate. However, the amounts of hydrogen sulfide adsorbed onto Zn-ACs were larger than that onto R-AC in equilibrium pressure below 100 hPa. The increase in the amount adsorbed onto Zn-ACs at the lower pressure region may be due to the chemical interaction of the zinc on the adsorbent and hydrogen sulfide.
  • Removal of Bisphenol A in Soil By Cyclodextrin Derivatives, M. Araki, N. Kawasaki, T. Nakamura, S. Tanada, Toxicological and Environmental Chemistry, 79, 23, 29,   2001 01 01 , 10.1080/02772240109358973, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0034981921&origin=inward
    Summary:The apparent aqueous solubility of the endocrine disruptor in hydroxypropyl-cyclodextrin (HPCD) solutions was investigated for evaluating the remediation of soil contamination and ground water pollution. The apparent solubility of bisphenol A (BPA) in water was significantly increased in HP-CD solutions. The solubilization effect of HP-CD's is caused by the formation of inclusion complexes of BPA and cyclodextrin. The relative aqueous-phase concentration of BPA linearly increased with increasing HP-CD concentration. The solubility of BPA increased in the order of the addition of HP-α-CD, HP-γ-CD, and HP-β-CD. However, it did not depend upon the degree of hydroxypropylation substitution. It is concluded that HP-CD may be utilized for the remediation of soil contamination.
  • Formation of trihalomethanes from dyes by ozone treatment, S. Tanada, N. Kawasaki, T. Nakamura, M. Araki, O. Shinohara, Toxicological and Environmental Chemistry, 79, 1, 7,   2001 01 01 , 10.1080/02772240109358971, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0034993890&origin=inward
    Summary:The amount of chloroform produced from dyes (orange II, methylene blue, and methylrosanilinium chloride) and humic acid by adding chlorine after the ozone treatments was investigated. Some dyes and humic acid were degraded by ozone and produced polar and acidic organic compounds. The amount of chloroform produced from orange II increased or decreased with the ozonization time, while that produced from methylene blue and humic acid decreased with ozonization time. Methylrosanilinium chloride did not produce the trihalomethane by chlorine disinfection. Thus, some but not all dyes produce trihalomethanes by ozone treatment and chlorine disinfection.
  • PII-2 Study on Moisture Control in House by Low Cost Carbonaceous Materials Produced from Foods By-products(Proceedings of the 45th Meeting of Japan Society of Physiological Anthropology) :, TANADA Seiki, NAKANISHI Akio, TAMAI Motoharu, KAWASAKI Naohito, NAKAMURA Takeo, Journal of physiological anthropology and applied human science, 20, 5,   2001 , http://ci.nii.ac.jp/naid/110002528399
  • Removal of 4-Nonylphenol by Carbonaceous Materials Produced form Cottonseed Shell as Organic By-products, ABE Ikuo, TABUCHI Takahiro, SHINOHARA Osamu, IWASAKI Satoshi, KAWASAKI Naohito, TANADA Seiki, Environmental science, 13, 5, 580, 585,   2000 12 31 , 10.11353/sesj1988.13.580, http://ci.nii.ac.jp/naid/10005338245
  • Studies on the Difference of Human Serum Metals in Sex and Age, Tanada Seiki, Nakamura Takeo, Kawasaki Naohito, Bulletin of Pharmaceutical Research and Technology Institute, 9, 9, 103, 112,   2000 12 14 , http://ci.nii.ac.jp/naid/110000560723
  • Study of Production of Rubber with Carbon Materials Produced from Organic By-products, ABE Ikuo, KAWASAKI Naohito, NAKAMURA Takeo, KONDO Takeshi, TANADA Seiki, Environmental science, 13, 2, 235, 238,   2000 05 31 , 10.11353/sesj1988.13.235, http://ci.nii.ac.jp/naid/10005337750
  • In Vitro Adsoxption Characteristics of Paraquat and Diquat with Activated Carbon Varying in Particle Size, T. Nakamura, N. Kawasaki, T. Tamura, S. Tanada, Bulletin Environmental Contamination and Toxicology, 64, 3, 377, 382,   2000 04 02 , 10.1007/s001280000011, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0034061091&origin=inward
  • Removal of 4-Nonylphenol by Carbonaceous Materials Produced from Cottonseed Shell as Organic By-products, Ikuo ABE, Takahiro TABUCHI, Osamu SHINOHARA, Satoshi IWASAKI, Naohito KAWASAKI, Seiki TANADA, Environmental Science, 13, 5, 580, 585,   2000 , 10.11353/sesj1988.13.580, http://ci.nii.ac.jp/naid/130004104338
    Summary:The recycling of organic by-products has attracted much interest. In this paper, techniques for producing carbonaceous adsorbents from an organic by-product and the application to removal of endocrine disruptors are described. Cottonseed shell as an organic by-products was carbonized at 873 K, and the cottonseed shell char was then activated in a rotary kiln with steam at 1123 K for different times to obtain microporous carbons. The specific surface area of the carbons obtained was nearly equal to those of commercial activated carbons. The amount of 4-nonylphenol adsorbed at equilibrium concentration above 20 g/L was high for the carbon with high specific surface area. The adsorption amount at extremely low concentration such as 1 g/L was high for the carbon with small mean pore diameter. Microporous carbons were produced next by air activation from cottonseed shell in the one-step treatment. Although the specific surface area of the carbon was small, the pore size was adequate for adsorbing 4-nonylphenol at low concentration. Therefore 4-nonylphenol could be efficiently removed from aqueous solution.
  • Relationship between Surface-Modified Activated Carbons and Volatile Chlorinated Hydrocarbons, O. Shinohara, N. Kawasaki, T. Nakamura, M. Araki, S. Tanada, Toxicological and Environmental Chemistry, 77, 151, 158,   2000 01 01 , 10.1080/02772240009358946, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0033732295&origin=inward
    Summary:The interactions between surface-modified activated carbons and trichloroethylene (TCE) or tetrachloroethylene (PCE) were estimated based on the adsorption isotherms and constants of the Freundlich and Langmuir equations. This result indicated that PCE strongly interacts with the activated carbon surface compared to TCE, because PCE is a more hydrophobic compound than TCE. The adsorption of TCE onto the activated carbon was effected to the presence of water, while that for PCE was not. The removal of TCE has to use for more hydrophobic activated carbon, that is, the activated carbon treated with hydrogen gas (AC-Red). On the other hand, the removal of PCE in water could be removed by the untreated activated carbon (AC). | The interactions between surface-modified activated carbons and trichloroethylene (TCE) or tetrachloroethylene (PCE) were estimated based on the adsorption isotherms and constants of the Freundlich and Langmuir equations. This result indicated that PCE strongly interacts with the activated carbon surface compared to TCE, because PCE is a more hydrophobic compound than TCE. The adsorption of TCE onto the activated carbon was effected to the presence of water, while that for PCE was not. The removal of TCE has to use for more hydrophobic activated carbon, that is, the activated carbon treated with hydrogen gas (AC-Red). On the other hand, the removal of PCE in water could be removed by the untreated activated carbon (AC).
  • Study of Production of Rubber with Carbon Materials Produced from Organic By-products., ABE Ikuo, KAWASAKI Naohito, NAKAMURA Takeo, KONDO Takeshi, TANADA Seiki, Environmental Science, 13, 2, 235, 238,   2000 , http://ci.nii.ac.jp/naid/130004303961
    Summary:The recycling of organic by-products has attracted much interest. In this paper, the technique which uses carbon materials produced from an organic by-product as a reinforcer of synthetic rubber is described. The organic by-products, coffee grounds, chaff and residue of Japanese spirits distilled from sweet potatoes, were carbonized at different carbonization temperatures. The carbon materials and carbon black are used for conventional synthetic rubber as the reinf orcer. The Mooney viscosity, the optimum vulcanization time, the hardness, the tensile strength, the tear strength, the compression set percentage and the permanent set of the carbon materials were measured to estimate the properties of synthetic rubber. The strength of the rubber produced with the carbon materials was weaker than that produced with the carbon black. However, the carbon materials can still be utilized as a reinf orcer of rubber.
  • In Vitro Acceleration on Paraquat and Diquat Adsorption onto Activated Carbon by Addition of Sodium Chloride, Nakamura Takeo, Kawasaki Naohito, Tanada Seiki, Bulletin of Pharmaceutical Research and Technology Institute, 8, 127, 134,   1999 12 14 , http://ci.nii.ac.jp/naid/110000560712
  • Formation of Trihalomethanes from Humic Acid by Ozone and Activated Carbon Fibers Treatments, Masahiro Uchida, Seishiro Ito, Seiki Tanada, Naohito Kawasaki, Takeo Nakamura, Toxicological and Environmental Chemistry, 72, 245, 252,   1999 12 01 , http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0033496143&origin=inward
    Summary:Humic acid, which is a trihalomethane precursor, was produced by the putrefaction of withered leaves. Trihalomethanes are produced by chlorine disinfection when tap water is treated with ozone and activated carbon in a purification plant. The amount of chloroform produced from humic acid by adding chlorine after the ozone and activated carbon fiber treatments was investigated. Humic acid was degraded by ozone to polar and acidic organic compounds by the addition of hypochlorite. The amount of chloroform produced increased with increasing treatment temperature, while it decreased with increasing ozonization time. It was also lowered by the addition of activated carbon fibers after the ozonization.
  • Recovery efficiency of the hydrofluorocarbon (HFC-134a) by activated carbons of different physicochemical properties, Naohito Kawasaki, Seiki Tanada, Takeo Nakamura, Takashi Ohue, Ikuo Abe, Toxicological and Environmental Chemistry, 69, 449, 458,   1999 12 01 , 10.1080/02772249909358724, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0008474849&origin=inward
    Summary:The adsorption characteristics of 1,1,1,2-tetrafluoroethane (HFC-134a) on activated carbon were investigated to evaluate the recovery efficiency of HFC-134a by six activated carbons (two granular activated carbons (GAC1 and GAC2), one high-surface area activated carbon (HAC), and three activated carbon fibers (ACF10, ACF15, and ACF20)). HFC-134a adsorption on the activated carbons increased with increase in the specific surface area and pore volume of the activated carbon. The differential heat of the HFC-134a adsorption decreased with increase in the percentage of the micropore volume to the total pore volume. The adsorption model of HFC-134a on the activated carbon could be based on the Langmuir model. The constant a of the Langmuir plot of HAC and ACF20 is smaller than GAC1 or GAC2 and ACF10 or ACF15, respectively. The constant Ws of HAC has the largest value. The constant a was correlated to the heat of adsorption. It is concluded that the largest amount of HFC-134a was adsorbed on HAC, and the least amount of interaction occurred between HFC-134a and the HAC. The amount of HFC-134a adsorbed on the activated carbons over time was applied to the Sameshima equation. The adsorption rate constant of HFC-134a on HAC was the largest. The HAC could be suitable for the recovery of HFC-134a. © 1999 OPA (Overseas Publishers Association) N.V. Published by license under the Gordon and Breach Science Publishers imprint.
  • A New Blind Signal Separation System Using Trigonometric Function, Shimada Hirokazu, Kawasaki Naoto, Shimada Yasuyuki, Usagawa Tsuyoshi, Ebata Masanao, Technical report of IEICE. EA, 99, 155, 15, 21,   1999 06 25 , http://ci.nii.ac.jp/naid/110003284549
    Summary:Noise cancellers are required for most speech recognition application in noisy environment such as in the compartment of a vehicle, there are many researches on this topic. Although the adaptive algorithm such as LMS are used, they are not always applicable. The blind separation methods are considered to be an alternative. However, most of blind separation methods can't separate the signals when each characteristics of direct-path has a zero-point. In this paper, a new bind separation method is proposed for 2-inputs and 2-outputs system. In this paper, direct- and cross- paths are represented using trigonometric function, the proposed system can separate the target signal from received signals even if the characteristics of direct path has zero-point.
  • Adsorption removal of paraquat and diquat onto activated carbon at different adsorption temperature, T. Nakamura, N. Kawasaki, H. Ogawa, S. Tanada, M. Kogirima, M. Imaki, Toxicological and Environmental Chemistry, 70, 275, 280,   1999 01 01 , http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0032789307&origin=inward
    Summary:The efficacy of activated carbon as an oral adsorbent in removing paraquat and diquat from purified water and physiological saline solution at different temperatures was investigated for the primary treatment of acute poisoning. The amounts of paraquat and diquat adsorbed onto activated carbon were large in low temperature condition. The adsorption mode of paraquat and diquat onto activated carbon was mainly physical adsorption. It was recognized that the high adsorption ratio of paraquat and diquat onto activated carbon was obtained by the administration of low temperature suspended solution which was a mixture of activated carbon and gastrointestinal lavage detergent.
  • Recovery of seven kinds of CFC and CFC replacements on high-surface area activated carbon, Seiki Tanada, Naohito Kawasaki, Takeo Nakamura, Ikuo Abe, Toxicological and Environmental Chemistry, 70, 483, 490,   1999 01 01 , http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0032802474&origin=inward
    Summary:The adsorption isotherms, the constants of the Dubinin-Radushkevich plots, and the constants of the Langmuir plots of chlorofluorocarbon (CFC) and CFC replacements on high-surface area activated carbon were investigated to estimate the recovery efficiency of CFC and CFC replacements. The adsorption and desorption of HFC134a on a high-surface area activated carbon was much easier than that of CFC113 and the CFC replacements. The recovery efficiency of CFC replacements depends on the hydrogen atoms in molecule. It is possible that the saturated amount adsorbed in the pores or on the surface of the activated carbon could be evaluated by the W(s) constant of the the Langmuir equation and the W(o) constant of the Dubinin-Radushkevich equation. The a constant of the Langmuir equation and the BE(o) constant of the Dubinin-Radushkevich equation depend on the molecular composition.
  • In vitro acceleration of paraquat and diquat adsorption onto activated carbon by addition of sodium chloride, NAKAMURA Takeo, OGAWA Hiroki, KAWASAKI Naohito, TANADA Seiki, YOSHIDA Yukie, IMAKI Masahide, Japanese Journal of Clinical Ecology, 7, 2, 74, 79,   1998 12 31
  • In vitro acceleration of paraquat and diquat adsorption onto activated carbon by addition of sodium chloride, NAKAMURA Takeo, OGAWA Hiroki, KAWASAKI Naohito, TANADA Seiki, YOSHIDA Yukie, IMAKI Masahide, 臨床環境医学 : 日本臨床環境医学会会誌 = Japanese journal of clinical ecology, 7, 2, 74, 79,   1998 12 31 , http://ci.nii.ac.jp/naid/10019091398
  • Studies on the Variation of Bio-Markers by Habitual Smoking, Tanada Seiki, Nakamura Takeo, Kawasaki Naohito, Bulletin of Pharmaceutical Research and Technology Institute, 7, 89, 96,   1998 12 20 , http://ci.nii.ac.jp/naid/110000560696
  • Adsorption Properties of Nonylphenol and Bisphenol A onto Activated Carbons, ABE Ikuo, IWASAKI Satoshi, FUKUHARA Tomoko, NAKANISHI Shunsuke, KAWASAKI Naohito, NAKAMURA Takeo, TANADA Seiki, 炭素, 1998, 184, 234, 235,   1998 10 31 , 10.7209/tanso.1998.234, http://ci.nii.ac.jp/naid/10011186068
  • In Vitro Paraquat and Diquat Removal by Substituted Chitosan Beads, NAKAMURA Takeo, KAWASAKI Naohito, TANADA Seiki, Journal of toxicological sciences, 23,   1998 07 24 , http://ci.nii.ac.jp/naid/110001806286
  • Adsorption of oxine copper as a germicide onto chitosan derivatives, NAKAMURA Takeo, TANADA Seiki, KAWASAKI Naohito, HARA Tsukasa, KYOTANI Syojiro, NISHIOKA Yutaka, Japanese Journal of Clinical Ecology, 7, 1, 27, 31,   1998 07 01 , http://ci.nii.ac.jp/naid/10029422459
  • Adsorption Properties of Nonylphenol and Bisphenol A onto Activated Carbons, ABE Ikuo, IWASAKI Satoshi, FUKUHARA Tomoko, NAKANISHI Shunsuke, KAWASAKI Naohito, NAKAMURA Takeo, TANADA Seiki, TANSO, 1998, 184, 234, 235,   1998 , http://ci.nii.ac.jp/naid/130004358364
    Summary:It is suspected that nonylphenol and bisphenol A have endocrine-disrupting effects, and a method of their removal is urgently sought. In this study, in order to obtain fundamental data on their removal by activated carbon adsorption, adsorption isotherms were measured. Adsorption data from four commercial activated carbons used for water treatment indicated that the chemicals were very adsorbable even in extremely low concentration.
  • Adsorption properties of CFC and CFC Replacements on Activated Carbon Containing Introduced Ionic Fluoride and Chloride, Tanada Seiki, Kawasaki Naohito, Nakamura Takeo, Annals of the Environmental Science Research Institute, Kinki University, 26, 1, 10,   1998 , http://ci.nii.ac.jp/naid/40004765348
  • Water sorption characteristics based on amino acid compositions of alkali-processed collagen fiber, K Boki, N Kawasaki, H Takahashi, K Minami, YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 117, 4, 248, 251,   1997 04 , 10.1248/yakushi1947.117.4_248, http://ci.nii.ac.jp/naid/110003649087
    Summary:Experimentally measured water vapor sorption isotherms (Sie) of alkali-processed collagen fibers C-20 and C-30 were compared with the theoretical isotherms (Sit) to elucidate the change of the microporous structure caused by the alkali-treatment during 20 and 30 d. The amino acid compositions of the collagen fibers were analyzed, then Sits were calculated from multiplying the degree of hydrophilicity of the sorption site. The amounts of sorbed water of SIe were greater than those of SI in the range of the water activity higher than 13%. The great difference was observed at C-20 rather than C-30. The difference between Sie and SIt was attributed to the large amount of sorbed water in the micropores. This result confirms that the change of collagen fiber during alkali process is explained by the microporous structure, not by the stability of the triple-helix structure.
  • Water sorption characteristics based on amino acid compositions of alkali-processed collagen fiber, K Boki, N Kawasaki, H Takahashi, K Minami, YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 117, 4, 248, 251,   1997 04 , 10.1248/yakushi1947.117.4_248, http://ci.nii.ac.jp/naid/10016243367
    Summary:Experimentally measured water vapor sorption isotherms (Sie) of alkali-processed collagen fibers C-20 and C-30 were compared with the theoretical isotherms (Sit) to elucidate the change of the microporous structure caused by the alkali-treatment during 20 and 30 d. The amino acid compositions of the collagen fibers were analyzed, then Sits were calculated from multiplying the degree of hydrophilicity of the sorption site. The amounts of sorbed water of SIe were greater than those of SI in the range of the water activity higher than 13%. The great difference was observed at C-20 rather than C-30. The difference between Sie and SIt was attributed to the large amount of sorbed water in the micropores. This result confirms that the change of collagen fiber during alkali process is explained by the microporous structure, not by the stability of the triple-helix structure.
  • Sensory Taste Evaluation of Milled Rice Cooked with Water Different in Hardness, Nakamura Takeo, Yurimoto Mayumi, Matsumoto Kazuoki, Kawasaki Naohito, Tanada Seiki, Japanese journal of food chemistry, 3, 2, 141, 144,   1997 02 24 , http://ci.nii.ac.jp/naid/110007367112
    Summary:食生活の欧米化に伴う慢性疾患への罹患およびそれらの疾患による死亡が懸念されている中にあった、伝統的な米飯を主体とする日本食が疾病予防の観点から注目されている。本研究においては、調理用水の水質、特に硬度の異なる水を用いて炊飯した米飯の食味(におい、かたさ、色つや、味、総合)について、19〜20才の女子学生をパネラーとして食味試験を行った。かたさ、色つや以外の食味試験項目については、比較的硬度の高い水で炊飯した米飯ほど、統計的に有意な高い評価点を示した。また硬度の高い水ほど、60℃および65℃における米に対する吸水率において大きな差が認められた。これらの結果より、炊飯米にカルシウム、マグネシウムといったミネラル成分を補充することにより、食味を向上させ、また慢性疾患の予防にもつながるであろうことが期待される。
  • Adsorption Removal of Chloroform and Bromoform by Activated Carbon Fiber, Masahiro Uchida, Takeo Nakamura, Naohito Kawasaki, Shinzo Kitayama, Seiki Tanada, Toxicological and Environmental Chemistry, 63, 1/4, 227, 231,   1997 01 01 , 10.1080/02772249709358532, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0030663803&origin=inward
    Summary:Adsorption characteristics of chloroform and bromoform onto activated carbon fibers (ACFs) for the safety drinking water were investigated. The amounts of chloroform and bromoform adsorbed onto ACFs decreased with their grade number that is the surface area and pore volume. Bromoform was more easily adsorbed onto ACFs than chloroform due to the difference in water solubility. The dominant factor of chloroform and bromoform adsorption onto ACFs may be the surface hydrophobicity of adsorbent rather than the surface area or pore volume.
  • Adsorption of Inhalational Anesthetics and Hydrochlorofluorocarbons on Activated Carbons as a Biological Model, Seiki TANADA, Naohito KAWASAKI, Takeo NAKAMURA, Ikuo ABE, Chemical and Pharmaceutical Bulletin, 45, 2, 231, 235,   1997 01 01 , 10.1248/cpb.45.231, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0030951778&origin=inward
    Summary:Chlorofluorocarbon (CFC) replacements have recently been used for their lower stability and because they have carbon-hydrogen bonds, which means that their atmospheric lifetime is expected to be much shorter than those of CFCs. The adsorption properties of 1,1,2-trichloro-1,2,2-trifluoroethane (CFC113) and its replacement compounds, 1,1-dichloro-2,2,2-trifluoroethane (HCFC123), 1,1-dichloro-1-fluoroethane (HCFC141b), and 1,1-dichloro-1,2,2,3,3- pentafluoropropane (HCFC225ca) on four kinds of activated carbons were investigated. The amount of CFC and HCFCs adsorbed on the activated carbon was concluded to depend upon the number of chloride and carbon atoms in their molecules. The adsorption isotherms of inhalational anesthetics (halothane, chloroform, enflurane, isoflurane, and methoxyflurane) on the activated carbon were measured to evaluate the action mechanism of inhalational anesthesia. The adsorption isotherms of CFC, HCFC, and the inhalational anesthetics were fitted to the Freundlich equation. The Freundlich constant N was well correlated with the minimum alveolar concentration (MAC) of the inhalational anesthetic: 1 MAC means that 50% of the patients will not move during a surgical operation. The adsorption mechanism of inhalational anesthetics on the surface of the activated carbon is concluded to be similar to the adsorption mechanism on a nerve cell. The anesthesia of CFC replacements can be estimated by the Freundlich constant N of the adsorption isotherms.
  • Studies on the Relationship between White Blood Cell Count and Serum Lipid Levels by the Difference of Smoking Habit, Tanada Seiki, Nakamura Takeo, Kawasaki Naohito, Bulletin of Pharmaceutical Research and Technology Institute, 6, 85, 92,   1997 , http://ci.nii.ac.jp/naid/110000560681
  • Chloroform Adsorption by Activated Carbon, T. Nakamura, N. Kawasaki, S. Tanada, K. Kawabata, M. Imaki, Toxicological and Environmental Chemistry, 57, 187, 192,   1996 12 01 , http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0030454552&origin=inward
    Summary:Chloroform removal by activated carbon with a view to elucidating the dominant factor was investigated for the assurance of safe water. A significant correlation was recognized between the amount of chloroform adsorbed and the amount of water adsorbed as the indicator of surface hydrophobicity of adsorbent. No significant correlations were recognized between the amount of chloroform adsorbed and the surface area, pore volume or surface pH. It was concluded that a dominant factor of chloroform adsorption by activated carbon was the degree of surface hydrophobicity of adsorbent.
  • Hydrogen Sulfide Removal by Iron Containing Activated Carbon, T. Nakamura, S. Tanada, N. Kawasaki, T. Hara, J. Fujisawa, K. Shibata, Toxicological and Environmental Chemistry, 55, 1/4, 279, 283,   1996 12 01 , 10.1080/02772249609358343, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0030498013&origin=inward
    Summary:Activated carbon modified by impregnation with iron (III) chloride solution (Fe-ACs) were studied to try to raise their adsorption capacity for hydrogen sulfide, a malodorous substance. The surface area and pore volume of activated carbon were decreased by impregnation, but the amount of hydrogen sulfide adsorbed onto Fe-AC was larger than that onto raw activated carbon (R-AC). In particular, a large increase of the amount adsorbed onto Fe-AC was noted at low equilibrium pressure. It was assumed that the increase of amount of hydrogen sulfide adsorbed onto Fe-AC was due to the chemical interaction between iron (III) chloride on the pores in addition to the physical adsorption onto pores of activated carbon. Fe-AC shows a high selectivity for hydrogen sulfide.
  • Effect of Activated Carbon Fibers with Different Physicochemical Properties on the Adsorption Rate of Volatile Chlorinated Hydrocarbons, S. Tanada, Y. Torii, T. Nakamura, N. Kawasaki, S. Kitayama, Toxicological and Environmental Chemistry, 54, 1/4, 131, 137,   1996 12 01 , 10.1080/02772249609358305, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0029716151&origin=inward
    Summary:The adsorption rate of volatile chlorinated hydrocarbons (TCE; trichloroethylene, PCE; tetrachloroethylene, MC; 1,1,1-trichloroethane) onto six kinds of activated carbon fibers (ACFs) was investigated. The specific surface area and the total pore volume of the ACFs became larger with an increase in the grade number. The Sameshima equation fit the adsorption isotherms and a correlation exists between the initial adsorption rate constant, k, for TCE and PCE versus the specific surface area. The mean values of the constant k increased in the order of MC, TCE. and PCE. The adsorption rate of TCE, PCE, and MC in the gaseous phase was influenced by the pore structure of the ACFs and the adsorption mechanism of TCE and PCE was almost determined by the pore packing, while that of MC cannot be explained by physicochemical properties of the ACFs alone.
  • Decomposition Degree of Chlorofluorocarbon(CFC)and CFC Replacements during Recovery with Surface-Modified Activated Carbon, Tanada Seiki, Kawasaki Naohito, Nakamura Takeo, Annals of the Environmental Science Research Institute, Kinki University, 24, 101, 106,   1996 12 , http://ci.nii.ac.jp/naid/40004765283
  • Adsorption of Diquat by Activated Carbon Fiber, NAKAMURA Takeo, KAWASAKI Naohito, TORII Yasuhiro, KITAYAMA Shinzo, TANADA Seiki, 臨床環境医学 : 日本臨床環境医学会会誌 = Japanese journal of clinical ecology, 5, 1, 18, 22,   1996 07 31 , http://ci.nii.ac.jp/naid/10029422020
  • Adsorption behavior of water molecules onto alpha-, beta-, and gamma-cyclodextrins and branched alpha-cyclodextrins, S Tanada, T Nakamura, N Kawasaki, T Kurihara, Y Umemoto, JOURNAL OF COLLOID AND INTERFACE SCIENCE, 181, 1, 326, 330,   1996 07 , 10.1006/jcis.1996.0385, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0030586377&origin=inward
    Summary:Moisture adsorption properties of alpha-, beta-, and gamma-cyclodextrin (CD) and branched alpha-CDs were investigated to elucidate the basis of the results of adsorption isotherms of water at 10, 20, and 30 degrees C, the differential heat of adsorption, the entropy of the adsorbed water, and the heat of immersion in water, It is concluded that the water molecules were adsorbed on the hydroxyl groups of the glucose molecule of alpha-CD, were first adsorbed on that of beta-CD and then were included in the pore structure of beta-CD, and were only included in the pare structure of gamma-CD. Branched alpha-CDs were developed and produced to increase the interaction with water molecules. However, the interaction between the branched alpha-CDs and the water was smaller than that between the virgin alpha-CD and the water, The solubility of branched, alpha-CD required a long time because the heat of immersion was larger in the order G(2)-alpha-CD and G(1)-alpha-CD or alpha-CD, It is considered that the side chain, glucosyl and maltosyl groups, decreased the interaction between the water molecule and the surface of the CD because of steric hindrance. Therefore, it is concluded that the side chain inhibited the melter adsorption of the inner molecule of CD. (C) 1996 Academic Press, Inc.
  • Studies on the Variation of Serum Zinc in Aged People by the Difference of Lifestyle, Tanada Seiki, Nakamura Takeo, Kawasaki Naohito, Bulletin of Pharmaceutical Research and Technology Institute, 5, 5, 105, 110,   1996 , http://ci.nii.ac.jp/naid/110000560669
  • Adsorption characteristics of diquat onto activated carbon from saline solution, T. Nakamura, N. Kawasaki, S. Tanada, H. Kondo, M. Imaki, Toxicological and Environmental Chemistry, 53, 153, 158,   1996 01 01 , http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=5744253550&origin=inward
    Summary:For the effective use of activated carbon as an antidote in acute diquat poisoning, the adsorption characteristics of diquat onto activated carbon from saline solution were investigated. The amount of diquat adsorbed onto activated carbon was increased with the increase of sodium chloride concentration in diquat solution. The rate of diquat removal by activated carbon from saline solution was also accelerated with the increase of sodium chloride concentration. These results suggest that the enhanced adsorptivity for diquat is due to the strengthening of electrostatic interaction between the surface of activated carbon and diquat with the increase of sodium chloride concentration in solution.
  • Adsorption Behavior of Water Pollutants onto Activated Carbon at Different Temperatures., NAKAMURA Takeo, IURA Yukihide, HARISHIGE Yoshiaki, ABE Ikuo, KAWASAKI Naohito, TANADA Seiki, SEIKATSU EISEI (Journal of Urban Living and Health Association), 40, 1, 23, 26,   1996 , http://ci.nii.ac.jp/naid/130003723751
    Summary:Using phenol, sodium dodecylbenzene sulfonate (DBS) and trimethyl benzyl ammonium chloride (TMBAC) as models, the adsorption behavior of water pollutant onto activated carbon at different temperatures was investigated. With all three substances and all activated carbon types, it was found that amount adsorbed decreased with increasing temperature, and that the effect of temperature was slight with large volumes of adsorbate and great with small volumes of adsorbate. With phenol and TMBAC, the amount adsorbed was greater with activated carbon with a small mean pore radius.<br>It was concluded that, where adsorption from dilute aqueous solutions is involved, as in the advanced treatment of tap water, treatment efficacy would be improved by lower temperature, but that, in the treatment of wastewater with high pollutant concentrations and in the removal of substances easily adsorbed onto activated carbon, the effect of temperature could be disregarded.
  • Adsorption characteristics of trichloroethylene on plasma-treated activated carbon, T. Nakamura, S. Tanada, N. Kawasaki, J. Izawa, T. Tokimoto, Toxicological and Environmental Chemistry, 47, 213, 222,   1995 01 01 , 10.1080/02772249509358142, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0029138392&origin=inward
    Summary:The adsorption characteristics of trichloroethylene (TCE) on untreated activated carbon (U-AC) and plasma-treated activated carbons (PT-ACs) were investigated on the basis of adsorption isotherms, differential heat of adsorption and entropy of adsorption to elucidate the difference between the U-AC and PT-ACs interactions with TCE. Differences in the amount of TCE adsorbed between U-AC and PT-ACs seemed to be attributable to the surface properties and micropore structure of the activated carbon. The interaction of the TCE - PT-AC surface was stronger than that of the TCE - U-AC surface. The amount of TCE adsorbed and strength of the TCE - activated carbon binding for the surface of the PT-AC depended on the hydrophobicity with inner the surface area of the activated carbon, that is, the porosity due to tetrafluoromethane plasma treatment. © 1995, Taylor & Francis Group, LLC. All rights reserved.
  • Studies on the Variation of Serum Calcium and Magnesium with Exercise for the Primary Prevention of Osteoporosis, Tanada Seiki, Nakamura Takeo, Kawasaki Naohito, Bulletin of Pharmaceutical Research and Technology Institute, 4, 71, 86,   1995 , http://ci.nii.ac.jp/naid/110000560654
  • MOISTURE SORPTION OF GELATIN POWDER AND COLLAGEN-FIBERS, K BOKI, N KAWASAKI, K MINAMI, YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 114, 9, 704, 709,   1994 09 , 10.1248/yakushi1947.114.9_704, http://ci.nii.ac.jp/naid/110003649528
    Summary:Moisture sorption properties of gelatin powder and collagen fibers were investigated on the basis of the moisture sorption isotherm, the differential heat of moisture sorption, the decrease in entropy of moisture sorption and the parameter constants of the applicable isotherm equation. The amount of moisture sorbed on collagen fibers was larger than that on gelatin powder. The water molecules were absorbed on gelatin itself rather than on the active sites of gelatin. They were adsorbed on the polar groups of constitutive amino acids at amounts of moisture sorbed up to one or two monolayers and then were absorbed into collagen fibers at higher monolayers. They were kept loosely in gelatin and tightly in collagen. The structural stability of collagen to moisture was higher than that of gelatin.
  • Micropores in Sodium Carboxymethyl Starch and Their Role in Moisture Sorption, BOKI Keito, KAWASAKI Naohito, MINAMI Kazuo, TADOKORO Sachie, Oyo Toshitsu Kagaku, 41, 2, 187, 191,   1994 , http://ci.nii.ac.jp/naid/130004091063
    Summary:The pore size distribution of sobium Carboxymethyl starch (Na-CMS) was obtained from the nitrogen adsorption isotherm to elucidate the relation between the degree of substitution (DS) and the microstructure of Na-CMSs and to evaluate the importance of the micropores in determining their greater moisture sorption capacity at lower water activity (a<SUB>w</SUB>). Although the total pore volume increased through carboxymethylation, the larger micropores (17.5<r&le;19.5&Aring;) disappeared in Na-CMSs with a lower DS (0.13-0.64) and larger micropores and smaller micropores (13.5&le;r&le;17.5&Aring;) appeared in Na-CMSs with a higher DS (0.81-1.01). The smaller micropores of Na-CMSs, rather than their larger micropores or mosopores (r>20&Aring;), increased the moisture contents at lower aw than 0.4.
  • Studies on the Urinary Mineral Concentrations in the Old, Tanada Seiki, Nakamura Takeo, Kawasaki Naohito, Bulletin of Pharmaceutical Research and Technology Institute, 3, 78, 83,   1994 , http://ci.nii.ac.jp/naid/110000560639
  • In vitro adsorption of paraquat onto substituted chitosan beads, T. Nakamura, S. Kyotani, N. Kawasaki, S. Tanada, Y. Nishioka, Japanese Journal of Hygiene, 48, 5, 973, 979,   1993 12 01 , 10.1265/jjh.48.973, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0027741418&origin=inward
    Summary:Paraquat removal by chitosan with different substituents was investigated in vitro for evaluation of chitosan as a paraquat adsorbent in emergency treatment for acute paraquat poisoning. Chitosan CM and SU, in which the hydroxyl group at the C6 position is replaced by a carboxymethyl and sulfonic group, respectively, removed paraquat abundantly in purified water. However an inhibitory effect of sodium chloride on paraquat removal by CM and SU was recognized. On the other hand, paraquat removal by cross-linked chitosan (BCW) was accelerated in saline solutions. It was recognized that more paraquat was removed by BCW chitosan when the sodium chloride concentration was less than 1.8%. It was confirmed that some chitosan beads (CM and SU) could function as effective paraquat adsorbents through in vitro experiments.
  • Adsorption Characteristics of Chlorhexidine onto Activated Carbon for Medical Waste Water Treatment, NAKAMURA Takeo, TANADA Seiki, KAWASAKI Naohito, HARA Tsukasa, IMAKI Masahide, MIYOSHI Tamotsu, Journal of Urban Living and Health Association, 37, 6, 249, 255,   1993 , 10.11468/seikatsueisei1957.37.249, http://ci.nii.ac.jp/naid/130003877722
    Summary:Adsorption removal of chlorhexidine, one of the disinfectants by activated carbon was discussed from standpoints of equilibrium amount adsorbed and adsorption rate for medical waste water treatment.<br>From the results of correlation between adsorption characteristics for chlorhexidine and properties of activated carbon, it was assumed that the dominant properties for the amount of chlorhexidine adsorbed were the surface area and the micropore volume of activated carbon.<br>And it was assumed that the dominant properties for the adsorption rate was the pore volume (20&Aring; <radius<100&Aring;) of activated carbon.
  • Moisture Sorption of Sodium Carboxymethyl Starch, BOKI Keito, KAWASAKI Naohito, MINAMI Kazuo, TADOKORO Sachie, Denpun Kagaku, 40, 4, 365, 373,   1993 , http://ci.nii.ac.jp/naid/130003866815
    Summary:Sodium carboxymethyl starches (Na-CMSs) with different degrees of substitution (DS) were prepared from potato starch (PS) and their moisture sorption properties were investigated. Little or no difference in moisture content was found between Na-CMSs (DSO&le;0.3) and PS. The moisture-sorption isotherms of Na-CMSs (DS&ge;0.6) rose appreciably at a water activity of 0.7. Appearance of new sorption sites due to sorption and swelling required a certain number of residual hydroxyl groups (DS&le;0.6). It was increasingly difficult for hydroxyl groups to appear at the surface of Na-CMSs with higher DS, and their new sorption sites had weaker activity. The entropy change of the moisture sorption on PS was considerably lower than that on the Na-CMSs. Moisture sorption on Na-CMSs (1) and (Z), and that on Na-CMSs (3)-(5) seemed to be composed of three and two energetic states, respectively. Moisture sorption on Na-CMSs (3)-(5) apparently holds a constant, energetically stable state after a drop in entropy change, while sorbed moisture affects the Na-CMSs because of their unstable porous structure. The Henderson, Chung and Pfost and Smith equations all fit the moisture-sorption isotherms of Na-CMSs. The constants of their equations indicated that the stability of the Na-CMS structure to moisture sorption gradually decreased with increasing DS, and that the bound fraction of sorbed moisture decreased while the condensed fraction increased.
  • Structural analysis of collagen fibres by nitrogen adsorption method, K. Boki, N. Kawasaki, K. Minami, H. Takahashi, Journal of Colloid and Interface Science,   1993 01 01 , 10.1006/jcis.1993.1157, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0027393095&origin=inward
    Summary:The pore size distribution and pore volume of untreated collagen fibres and collagen treated with calcium hydroxide for 10, 20 and 30 days are investigated by the nitrogen adsorption method.
  • Structural Analysis of Micropores of Starches by Moisture Adsorption-Desorption Method., BOKI Keito, KAWASAKI Naohito, MINAMI Kazuo, Journal of the Japanese Society of Starch Science, 39, 4, 271, 276,   1992 , http://ci.nii.ac.jp/naid/130003715676
    Summary:The pore size distribution curves of rice, corn, potato, sweet potato and kuzu starches were investigated to elucidate the relationship between the types of A, B and C forms and their porosity. Pore size distribution curves in the regions of pore radii 4 to 10.5 &Aring; and 10.5 to 300 A were determined by the micropore (MP) method from the moisture adsorption isotherms and the Barrett Joyner Halenda (BJH) method from the moisture desorption isotherms, respectively. Moisture content at higher water activity than 0. 4, saturated moisture content and hysteresis loop of B form (potato) starch were larger than those of C form (kuzu, sweet potato) and A form (rice, corn) starches. The maximum peak at the vicinity of pore radius 8 A was observed not in the A and C form starches but in the B form starch . The plots of pore volume in the region of pore radii 10.5 to 300 A and B form percentage gave a straight line with correlation coefficient of 0.955.
  • Synergistic cytotoxicity caused by forming a complex of copper and 2,9-dimethyl-1,10-phenanthroline in cultured vascular endothelial cells, Takehiro Nakamura, Eiko Yoshida, Tomoya Fujie, Fumihiko Ogata, Chika Yamamoto, Naohito Kawasaki, Toshiyuki Kaji, Journal of Toxicological Sciences, 42, 6, 683, 687,   2017 12 , 10.2131/jts.42.683
    Summary:© 2017, Japanese Society of Toxicology. All rights reserved. Organic-inorganic hybrid molecules, which are composed of organic-ligand(s) and metal(s), are indispensable as synthetic reagents in chemistry, but they have made very little in the way of contributions to biological research. Previously, we reported that the cytotoxicity of organic-inorganic hybrid molecules in vascular endothelial cells depends on interactions between the intramolecular metal and ligand, but remains independent of the hydrophobicity of the intramolecular metal(s). Herein, we show a synergistic cytotoxicity produced by forming a complex of copper and 2,9-dimethyl-1,10-phenanthroline in vascular endothelial cells that depends on the intracellular accumulation of copper.
  • Evaluation of a novel method for measurement of intracellular calcium ion concentration in fission yeast, Fumihiko Ogata, Ryosuke Satoh, Ayako Kita, Reiko Sugiura, Naohito Kawasaki, Journal of Toxicological Sciences, 42, 2, 159, 166,   2017 , 10.2131/jts.42.159
    Summary:© 2017, Japanese Society of Toxicology. All rights reserved. The distribution of metal and metalloid species in each of the cell compartments is termed as “metallome”. It is important to elucidate the molecular mechanism underlying the beneficial or toxic effects exerted by a given metal or metalloid on human health. Therefore, we developed a method to measure intracellular metal ion concentration (particularly, intracellular calcium ion) in fission yeast. We evaluated the effects of nitric acid (HNO3), zymolyase, and westase treatment on cytolysis in fission yeast. Moreover, we evaluated the changes in the intracellular calcium ion concentration in fission yeast in response to treatment with/without micafungin. The fission yeast undergoes lysis when treated with 60% HNO3, which is simpler and cheaper compared to the other treatments. Additionally, the intracellular calcium ion concentration in 60% HNO3-treated fission yeast was determined by inductively coupled plasma atomic emission spectrometry. This study yields significant information pertaining to measurement of the intracellular calcium ion concentration in fission yeast, which is useful for elucidating the physiological or pathological functions of calcium ion in the biological systems. This study is the first step to obtain perspective view on the effect of the metallome in biological systems.
  • Adsorption of Au(III) from Aqueous Solution by Calcined Gibbsite, Fumihiko Ogata, Naohito Kawasaki, JOURNAL OF CHEMICAL AND ENGINEERING DATA, 59, 2, 412, 418,   2014 02 , 10.1021/je400888r, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84894102686&origin=inward
    Summary:Gibbsite (GB) was prepared in this work by calcination between (200 and 1000) degrees C (GB200 and GB1000, respectively). Properties of the GBs prepared over this range of temperatures, such as their morphologies, crystallinities, specific surface areas, the number of hydroxyl groups, pore volumes, and mean pore diameters were investigated. The amount of Au(III) adsorbed onto the GBs was also evaluated., Our findings show that the amount of Au(III) adsorbed onto the GBs is related to the specific surface area and the number of hydroxyl groups. In this study, GB400, that is, GB calcined at 400 degrees C, had the largest specific surface area and number of hydroxyl groups, as well as the largest amount of adsorbed Au(III). Furthermore, the most suitable pH for the adsorption of Au(III) onto GB400 was approximately 6.0, and the gold chloro-hydroxy species [AuCl2(OH)(2)](-) was selectively adsorbed at this temperature. The equilibrium for adsorption was reached within 24 h, and the experimental data were fit to the pseudo-second-order model. The adsorption isotherm data were better characterized by the Langmuir model than the Freundlich model. The presence of chloride ions (Cl-) affected the adsorption of Au(III) onto GB400. The increase of Delta G with temperature showed that the adsorption was endothermic and more favorable at higher temperatures. The positive Delta H values also indicated that Au(III) adsorption on GB400 was endothermic. The positive Delta S values suggest an increase in randomness at the solid solution interface during the adsorption process. GB400 could be used for at least three Au(III) adsorption/desorption cycles. Collectively, these results suggest that GB400 would be useful for the adsorption of Au(III) from aqueous solutions.
  • Adsorption of rhodium(III) from plating solutions by calcined gibbsite, Fumihiko Ogata, Yuka Iwata, Naohito Kawasaki, TOXICOLOGICAL AND ENVIRONMENTAL CHEMISTRY, 95, 6, 890, 898,   2013 07 , 10.1080/02772248.2013.840377, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84887069079&origin=inward
    Summary:Gibbsite calcined at 400 degrees C (GB400) was prepared, and its ability to adsorb rhodium(III) was investigated. Optimal pH, effect of contact time, temperature, adsorption isotherms, and recovery percentage were evaluated. The optimal pH was 6.3. The adsorption equilibrium was achieved within 24h. The adsorption rate was found to be of pseudo-first order. The experimental data were fitted to both the Freundlich (r = 0.90-0.93) and Langmuir (r = 0.94-0.96) equations. The amount of rhodium(III) adsorbed decreased with increasing temperature. Rhodium(III) being adsorbed from phosphate or sulfate plating solution was recovered using hydrochloric acid and sodium hydroxide solutions at 1, 10, and 100mmol L-1.
  • Development of Novel Carbon Fiber produced from Waste Fiber by Cabonization, Naohito Kawasaki, Hisato Tominaga, Fumihiko Ogata, Kenji Inoue, Moe Kankawa, JOURNAL OF OLEO SCIENCE, 61, 10, 593, 600,   2012 10 , http://ci.nii.ac.jp/naid/40019417198
    Summary:The volume of waste fiber has increased rapidly in recent years, and this trend is expected to continue. In this study, therefore, we attempted to convert waste fiber to carbonaceous materials by carbonization and investigated the basic properties of the resulting carbonized fibers. The results demonstrated that pores tend to form and specific surface areas change substantially, depending on the carbonization conditions. The carbonization conditions resulting in the largest specific surface areas included a temperature increase and retention times of 2 h. Carbonization temperatures resulting in the maximum values of 1000 degrees C were 900-1000 degrees C for wool and 1000 degrees C for both polyester and cotton. In particular, the specific surface area of cotton after carbonization at 1000 degrees C was 1253 m(2)/g, and scanning electron microscopy (SEM) micrographs showed that cotton retained its fibrous form after carbonization. Thus, it is possible to inexpensively convert waste fibers to carbonaceous material by carbonization. The results indicate that for cotton fiber in particular, the practical application of this process to the production of low-cost fibrous activated carbon would be possible, since cotton fiber retains its fibrous form under carbonization.
  • Development of Novel Carbon Fiber produced from Waste Fiber by Cabonization, Naohito Kawasaki, Hisato Tominaga, Fumihiko Ogata, Kenji Inoue, Moe Kankawa, JOURNAL OF OLEO SCIENCE, 61, 10, 593, 600,   2012 10 , http://ci.nii.ac.jp/naid/130004435952
    Summary:The volume of waste fiber has increased rapidly in recent years, and this trend is expected to continue. In this study, therefore, we attempted to convert waste fiber to carbonaceous materials by carbonization and investigated the basic properties of the resulting carbonized fibers. The results demonstrated that pores tend to form and specific surface areas change substantially, depending on the carbonization conditions. The carbonization conditions resulting in the largest specific surface areas included a temperature increase and retention times of 2 h. Carbonization temperatures resulting in the maximum values of 1000 degrees C were 900-1000 degrees C for wool and 1000 degrees C for both polyester and cotton. In particular, the specific surface area of cotton after carbonization at 1000 degrees C was 1253 m(2)/g, and scanning electron microscopy (SEM) micrographs showed that cotton retained its fibrous form after carbonization. Thus, it is possible to inexpensively convert waste fibers to carbonaceous material by carbonization. The results indicate that for cotton fiber in particular, the practical application of this process to the production of low-cost fibrous activated carbon would be possible, since cotton fiber retains its fibrous form under carbonization.
  • Granulation of gibbsite with inorganic binder and its ability to adsorb Mo(VI) from aqueous solution, Fumihiko Ogata, Hisato Tominaga, Hitoshi Yabutani, Atsushi Taga, Naohito Kawasaki, TOXICOLOGICAL AND ENVIRONMENTAL CHEMISTRY, 94, 4, 650, 659,   2012 , 10.1080/02772248.2012.671325, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84859753162&origin=inward
    Summary:In this study, we prepared a new adsorbent and evaluated its ability to adsorb Mo(VI). Gibbsite was granulated with colloidal alumina or colloidal silica. The amount of Mo(VI) adsorbed onto granular gibbsite with a binder, effect of contact time and pH on the adsorption of Mo(VI), and column experiments were investigated. The amount of Mo(VI) adsorbed was greater in the order of ST12 (colloidal silica, 12%) < AS10 (colloidal alumina, 10%) < GB400 (calcined gibbsite at 400 degrees C). Adsorption isotherms data were fitted to the Freundlich equation (correlation coefficient: 0.941-0.978), suggesting monomolecular adsorption on a heterogeneous surface. The amount of Mo(VI) adsorbed onto granular gibbsite with a binder was correlated with the amount of hydroxyl groups rather than the specific surface area. The adsorption rate data of Mo(VI) were fitted to the pseudo-second-order equation, which indicated that the rate limiting step may be chemisorption. Recovery of Mo(VI) using AS10 packed in a column was 95.6%. After five adsorption and desorption steps, adsorption and desorption ability of Mo(VI) using AS10 was unchanged. These results suggest that AS10 packed in a column could be useful for the recovery of Mo(VI).
  • Removal of cadmium and copper by vegetable biomass treated with hydrochloric acid, Naohito Kawasaki, Hisato Tominaga, Fumihiko Ogata, Kazuaki Kakehi, CHEMICAL ENGINEERING JOURNAL, 157, 1, 249, 253,   2010 02 , 10.1016/j.cej.2009.11.028, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=75149117286&origin=inward
    Summary:Food waste is discharged abundantly, and while some of it is reused, most is incinerated. The recycling of soybean waste and wheat bran as vegetable biomass needs to become established, and the ability to remove Cd(2+) and Cu(2+) by vegetable biomass needs to be estimated. The estimations performed here revealed that the amounts of Cd(2+) and Cu(2+) adsorbed onto untreated vegetable biomass were larger than those adsorbed onto defatted biomass. This indicates that the adsorption of Cd(2+) and Cu(2+) onto vegetable biomass may depend on fat content. On the other hand, the elution percentage of vegetable biomass increased as the concentration of hydrochloric acid increased. The elution is due to the degradation of protein in the biomass by the acid. The amounts of Cd(2+) and Cu(2+) adsorbed decreased as more than 0.10 mol/L of the concentration of hydrochloric acid increased. Cd(2+) and Cu(2+) are adsorbed on vegetable biomass by their adsorption onto protein. The amounts of Cu(2+) adsorbed onto soybean waste and wheat bran in a binary-solution system are larger than those in a single-solution system. However, less Cd(2+) was adsorbed onto wheat bran in the binary system than in the single one. These results indicated that the amount of Cu(2+) adsorbed increases in the presence of Cd(2+). Either the adsorption of Cd(2+) onto wheat bran is inhibited by Cu(2+) or the adsorptions of Cd(2+) and Cu(2+) onto the biomass were affected by each other. (C) 2009 Elsevier B. V. All rights reserved.
  • Removal of NO3--N and NO2--N with Coffee Grounds by Ion Exchange, Fumihiko Ogata, Hitoshi Yabutani, Hisato Tominaga, Isao Yamaguchi, Naohito Kawasaki, KAGAKU KOGAKU RONBUNSHU, 36, 4, 293, 298,   2010 , 10.1252/kakoronbunshu.36.293, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=77955353623&origin=inward
    Summary:To investigate the recycling of coffee grounds (CGs), the surfaces of CGs were modified with CaCl2 solution, and the adsorption mechanism of NO3--N and NO2--N on these surfaces was evaluated. Maximun adsorption of NO3--N and NO2--N was observed with CGs carbonized at 600 degrees C (CG600), and the amounts adsorbed increased with temperature, at the time of adsorption, reaching equilibrium after 24 h. The amount of chloride ions eluted from CG600 increased with the amount of NO3--N and NO2--N adsorbed. The adsorption isotherms of NO3--N and NO2--N were fitted by the Freundlich and the Langmuir equations. These results indicated that NO3--N and NO2--N were adsorbed onto CG600 by ion exchange. CGs treated with CaCl2 solution can be utilized for the removal of NO3--N and NO2--N from drinking water.
  • Adsorption Ability of Arsenic (III) and Chromium (VI) onto Granular GB, Fumihiko Ogata, Naohito Kawasaki, Mineaki Kabayama, Kazuaki Kakehi, KAGAKU KOGAKU RONBUNSHU, 35, 1, 42, 46,   2009 , 10.1252/kakoronbunshu.35.42, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=70249095623&origin=inward
    Summary:Arsenic (III) and chromium (VI) are known to be harmful for human health. In this study, gibbsite (GB) was granulated using ethyl cellulose or alumina sol 520 for the removal of arsenic (III) and chromium (VI). Two kinds of granular GBs had the ability to adsorb arsenic (III) and chromium (VI), with arsenic (III) being adsorbed in greater amount. Use of ethyl cellulose to prepare granular GB may not be economically suitable, because the production process is complex and requires the use of solvent. The amount of arsenic (III) and chromium (VI) adsorbed onto GB was slightly decreased by the granulation. The amount of arsenic (III) adsorbed onto granular GB in a binary solution system was greater than that in single solution system, while the amount of chromium (VI) adsorbed was similar in both systems. The adsorption mechanism of arsenic (III) and chromium (VI) is thought to dependent on the affinity between the metals and the surface or porosity of granular GB. The prepared GB could be utilized for removal of arsenic (III) or chromium (VI) in an aqueous environment.
  • Relationship between anion adsorption and physicochemical properties of aluminum oxide, Naohito Kawasaki, Fumihiko Ogata, Kouzou Takahashi, Mineaki Kabayama, Kazuaki Kakehi, Seiki Tanada, JOURNAL OF HEALTH SCIENCE, 54, 3, 324, 329,   2008 06 , 10.1248/jhs.54.324, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=44849109577&origin=inward
    Summary:This study investigated the adsorption capacity and adsorption mechanism of phosphate by calcined aluminum oxide (GB) at temperatures of 200 to 1150 degrees C. The results showed that GB and GB calcined at a temperature of 200 degrees C exhibited almost no adsorption capacity, and GB calcined at temperatures of 300 or 400 degrees C exhibited the highest adsorption capacity. After that, adsorption capacity tended to decrease with increasing calcination temperature. The specific surface area and the concentration of surface hydroxyl groups exhibited the highest values in GB calcined at temperatures of 300 and 400 degrees C. From the above facts, it is conjectured that the specific surface area and concentration of surface hydroxyl groups contribute to the adsorption of phosphate in calcined GB. The results of X-ray diffraction showed that the structure of GB changed drastically at temperatures of 200 to 300 degrees C and 900 to 1000 degrees C. Also, it was evident that phosphate was adsorbed selectively even in complex solution systems containing chloride, nitrate, sulfate, hydrogen carbonate and phosphate ions, and that calcined GB is suitable for adsorption of: phosphate. For the adsorption of phosphate, it was found that the optimum pH is around 4. When calcined GB is suspended in purified water, it is thought that hydroxyl groups form through dissociative adsorption with water molecules, and that these hydroxyl groups conduct ion exchange with phosphate.
  • Removal of lead ions in drinking water by coffee grounds as vegetable biomass, T Tokimoto, N Kawasaki, T Nakamura, J Akutagawa, S Tanada, JOURNAL OF COLLOID AND INTERFACE SCIENCE, 281, 1, 56, 61,   2005 01 , 10.1016/j.jcis.2004.08.083, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=9644255782&origin=inward
    Summary:In an attempt to reuse food waste for useful purposes, we investigated the possibility of using coffee grounds to remove lead ions from drinking water. We studied the lead ion adsorption characteristics of coffee beans and grounds by measuring their fat and protein content, adsorption isotherms for lead ions, and adsorption rates for lead ions. The number of lead ions adsorbed by coffee grounds did not depend on the kind of coffee beans or the temperature at which adsorption tests were performed. The rate of lead ion adsorption by coffee grounds was directly proportional to the amount of coffee grounds added to the solution. When coffee grounds were degreased or boiled, the number of lead ions decreased. When proteins contained in coffee grounds were denatured, the lead ion adsorption was considerably reduced. The lead ion adsorption capacity of coffee grounds decreased with increased concentration of perchloric acid used for treating them and disappeared with 10% perchloric acid. The experiments demonstrated that proteins contained in coffee beans depend upon the adsorption of lead ion. The present study gave an affirmative answer to the possibility Of using, coffee grounds, an abundant food waste, for removing lead ions from drinking water. (C) 2004 Elsevier Inc. All rights reserved.
  • Study on adsorption kinetic of aromatic hydrocarbons onto activated carbon in gaseous flow method, N Kawasaki, H Kinoshita, T Oue, T Nakamura, S Tanada, JOURNAL OF COLLOID AND INTERFACE SCIENCE, 275, 1, 40, 43,   2004 07 , 10.1016/j.jcis.2004.01.066
    Summary:The adsorption behavior of benzene, toluene, o-xylene, m-xylene, and p-xylene onto activated carbon was investigated using the flow method. The removal efficiency of aromatic hydrocarbons in the gaseous phase was estimated based on the adsorption kinetic constants and the saturated amount of aromatic hydrocarbons adsorbed on the activated carbon. The saturated amount of benzene and toluene adsorbed was greater than that of xylene adsorbed because the molecular sizes of benzene and toluene are smaller than that of xylene. The adsorption kinetic constant increased in the order of xylene, toluene, and benzene. Those of the three xylene isomers were similar. These results indicated that the adsorption rate of benzene by the activated carbon was the fastest and the kinetic constant depended upon the different between the boiling point and the melting point and the molecular size of the aromatic hydrocarbons. (C) 2004 Elsevier Inc. All rights reserved.
  • Adsorption of fluoride ions onto carbonaceous materials, Abe, I, S Iwasaki, T Tokimoto, N Kawasaki, T Nakamura, S Tanada, JOURNAL OF COLLOID AND INTERFACE SCIENCE, 275, 1, 35, 39,   2004 07 , 10.1016/j.jcis.2003.12.031, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=2442698693&origin=inward
    Summary:The characteristics of fluoride ion adsorption onto carbonaceous materials were derived as adsorption isotherms at different temperatures and in different pH solutions. The fluoride ion was adsorbed into pores in carbonaceous materials produced from wood; the larger the specific surface area, the more fluoride ions adsorbed. Bone char was the most effective adsorbent. The composition of bone char includes calcium phosphate, calcium carbonate, and so on. This suggests that the phosphate ion in bone char was exchanged with a fluoride ion. Moreover, the mechanism of fluoride ion adsorption onto bone char is clearly chemical in nature because the amount of fluoride ion adsorbed onto bone char increased with increasing temperature and decreasing pH. The amount of fluoride ion adsorbed onto bone char was also shown to depend on the concentration of sodium chloride in solution because of the "salting-out" effect. The adsorption of fluoride ion onto bone char is endothermic. Bone char can be utilized to remove fluoride ions from drinking water. (C) 2004 Elsevier Inc. All rights reserved.
  • Decolorization of acidic dye by charcoal from coffee grounds, T Nakamura, T Tokimoto, T Tamura, N Kawasaki, S Tanada, JOURNAL OF HEALTH SCIENCE, 49, 6, 520, 523,   2003 12 , 10.1248/jhs.49.520, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=24744469419&origin=inward
    Summary:From the viewpoints of decreasing environmental burdens and recycling of materials, the adsorption ability of charcoal from coffee grounds for acidic dye (acid orange 7) removal was investigated by the batch method. Differences in the removal ratio and removal rate of acid orange 7 could be explained by differences in the properties of charcoal such as specific surface area and pore volume. In the relationship between the amount of acid orange 7 adsorbed at each elapsed time and the square root of elapsed time, a good linearity was recognized. Since the good linearity between the acid orange 7 adsorption and the square root of elapsed time was recognized, the intraparticle diffusion of acid orange 7 onto pores of adsorbents was identified as the rate-limiting step in the adsorption process.
  • Paraquat and diquat removal by citosan derivetives, Jpn. J. Clin. Ecol., 7,   2003
  • Characterization of water adsorption onto carbonaceous materials produced from food wastes, A Nakanishi, M Tamai, N Kawasaki, T Nakamura, M Araki, S Tanada, JOURNAL OF COLLOID AND INTERFACE SCIENCE, 255, 1, 59, 63,   2002 11 , 10.1006/jcis.2002.8651
    Summary:The recycling of organic wastes has become very important and the development of technology for recycling organic wastes needs to sustain industrial development. In this study, techniques for producing carbonaceous materials from organic wastes are described and water adsorption is characterized. The organic wastes used are coffee grounds and oolong tea leaves carbonized at 673 to 1073 K. The iodine adsorption capacity of the carbonaceous materials increased with increased carbonization temperature. The amount of water adsorbed onto the carbonization materials produced from oolong tea leaves at 873 K for 2 h was the highest. The Freundlich constant 1/n and the differential heat of adsorption of the carbonaceous materials produced from oolong tea leaves were greater than that of the carbonaceous materials produced from coffee grounds. The ability to humidity control can be estimated by the difference between the amount of water adsorbed relative pressure 0.90 and that at relative pressure 0.55. The ability to humidity control was the greatest for the carbonaceous materials produced from the oolong tea leaves at 873 K for 2 h and did not depend upon the adsorption temperature. These results indicated that the carbonaceous materials produced from oolong tea leaves at 873 K for 2 h could have more humidity control. (C) 2002 Elsevier Science (USA).
  • Adsorption of dyes onto carbonaceous materials produced from coffee grounds by microwave treatment, M Hirata, N Kawasaki, T Nakamura, K Matsumoto, M Kabayama, T Tamura, S Tanada, JOURNAL OF COLLOID AND INTERFACE SCIENCE, 254, 1, 17, 22,   2002 10 , 10.1006/jcis.2002.8570, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0036399287&origin=inward
    Summary:Organic wastes have been burned for reclamation. However, they have to be recycled and reused for industrial sustainable development. Carbonaceous materials were produced from coffee grounds by microwave treatment. There are many phenolic hydroxyl and carboxyl groups on the surface of carbonaceous materials. The base consumption of the carbonaceous materials was larger than that of the commercially activated carbon. The carbonaceous materials produced from coffee grounds were applied to the adsorbates for the removal of basic dyes (methylene blue and gentian violet) in wastewater. This result indicated that the adsorption of dyes depended upon the surface polar groups on the carbonaceous materials. Moreover, the Freundlich constants of isotherms for the adsorption of methylene blue and gentian violet onto the carbonaceous materials produced from coffee grounds were greater than those for adsorption onto activated carbon or ceramic activated carbon. The interaction was greatest between the surface or porosity of the carbonaceous materials and methylene blue and gentian violet. The microwave treatment would be useful for the carbonization of organic wastes to save energy. (C) 2002 Elsevier Science (USA).
  • Adsorption characteristics of bisphenol A onto carbonaceous materials produced from wood chips as organic waste, A Nakanishi, M Tamai, N Kawasaki, T Nakamura, S Tanada, JOURNAL OF COLLOID AND INTERFACE SCIENCE, 252, 2, 393, 396,   2002 08 , 10.1006/jcis.2002.8387, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0036968022&origin=inward
    Summary:Many organic by-products have been discharged by humans, and the development of technology for recycling organic by-products has attracted much interest. In this paper, the techniques for producing carbonaceous adsorbents from an organic by-product an an application to remove endocrine disruptors are described. Wood chips as an organic by-product were carbonized at 873 to 1073 K. The iodine adsorption capacity of the obtained carbonaceous materials increased with increasing carbonization temperature. The amount of bisphenol A adsorbed on the carbonized materials produced from Sugi and Hinoki at a 1073 K carbonization temperature was higher than that of activated carbon. The Freundlich constant, I IN, of the carbonaceous materials produced from Sugi chips, Sugi sawdust, and Hinoki sawdust was similar to that of the activated carbon. This result indicated that the affinity between bisphenol A and the carbonaceous materials or the activated carbon was similar. Their Freundlich constant, K, was greater than that of the activated carbon. Hence, bisphenol A could be efficiently removed by the carbonaceous materials. (C) 2002 Elsevier Science (USA).
  • Adsorption characteristics of bisphenol A onto carbonaceous materials produced from wood chips as organic waste, A Nakanishi, M Tamai, N Kawasaki, T Nakamura, S Tanada, JOURNAL OF COLLOID AND INTERFACE SCIENCE, 252, 2, 393, 396,   2002 08 , 10.1006/jcis.2002.8387, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0037103905&origin=inward
    Summary:Many organic by-products have been discharged by humans, and the development of technology for recycling organic by-products has attracted much interest. In this paper, the techniques for producing carbonaceous adsorbents from an organic by-product an an application to remove endocrine disruptors are described. Wood chips as an organic by-product were carbonized at 873 to 1073 K. The iodine adsorption capacity of the obtained carbonaceous materials increased with increasing carbonization temperature. The amount of bisphenol A adsorbed on the carbonized materials produced from Sugi and Hinoki at a 1073 K carbonization temperature was higher than that of activated carbon. The Freundlich constant, I IN, of the carbonaceous materials produced from Sugi chips, Sugi sawdust, and Hinoki sawdust was similar to that of the activated carbon. This result indicated that the affinity between bisphenol A and the carbonaceous materials or the activated carbon was similar. Their Freundlich constant, K, was greater than that of the activated carbon. Hence, bisphenol A could be efficiently removed by the carbonaceous materials. (C) 2002 Elsevier Science (USA).
  • Inclusion behavior of 4-nonylphenol into cyclodextrin derivatives, N Kawasaki, M Araki, T Nakamura, S Tanada, JOURNAL OF COLLOID AND INTERFACE SCIENCE, 238, 1, 215, 218,   2001 06 , 10.1006/jcis.2001.7517, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0035387947&origin=inward
    Summary:The solubilities of 4-nonylphenol in five kinds of hydroxypropylcyclodextrin (HP-CDs) solutions were investigated in order to evaluate them for soil remediation. The relative aqueous-phase concentration of 4-nonylphenol linearly increased with the increasing HP-CD concentration. The addition of HP-beta -CD (degree of substitution, D,S, = 0.6) produced the largest change because the inner core of HP-beta -CD is the most hydrophobic. The solubility of 4-nonylphenol in the HP-CD solutions depended upon the cavity diameter and the degree of HP-CD substitution. Both ozone and activated carbon treatments have been using for removing organic compounds and foul odor compounds from tap water. As the inclusion complexes moved into the groundwater, the ozone degradation of the inclusion complexes was estimated. The 4-nonylphenol-HP-CD inclusion complexes were easily degraded by ozone. The degree of degradation increased with the increasing ozonization time. Weakly acidic compounds were produced from the 4-nonylphenol-HP-CD inclusion complexes by ozonization, HP-CDs could be used for the removal of 4-nonylphenol from soil, (C) 2001 Academic Press.
  • Formation of Triharomethones from Dyes by Ozone Treatment, Toxicological and Environmental Chemistry, 79, 1,   2001
  • Trihalomethane removal by activated carbon fiber, T Nakamura, N Kawasaki, M Araki, K Yoshimura, S Tanada, JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART A-TOXIC/HAZARDOUS SUBSTANCES & ENVIRONMENTAL ENGINEERING, 36, 7, 1303, 1310,   2001 , 10.1081/ESE-100104879, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0034837501&origin=inward
    Summary:For the safety of drinking water, trihalomethanes are removed by adsorption onto activated carbon fiber from single-component solutions. The amounts adsorbed onto adsorbents with large surface area and/or pore volume were small. Stronger surface hydrophobicity of adsorbent was correlated with a larger amount of trihalomethanes adsorbed. A trihalomethane with bromine was adsorbed to a greater extent than that with chlorine. The differences in the amounts adsorbed among trihalomethanes can be explained by the polarity of trihalomethane molecules. The amount of trihalpmethanes adsorbed was mainly dominated by the strength of hydrophobicity of activated carbon fibers.
  • Characteristics of cyclodextrin adsorption onto activated carbons, Abe, I, T Fukuhara, N Kawasaki, M Hitomi, Y Kera, JOURNAL OF COLLOID AND INTERFACE SCIENCE, 229, 2, 615, 619,   2000 09 , 10.1006/jcis.2000.7070, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0034665926&origin=inward
    Summary:Whereas the amount of cyclodextrin (CD) adsorbed onto the large-pore activated carbon A (AC-A) increased with the number of glucose units, the amount adsorbed onto the small-pore activated carbon B (AC-B) showed the opposite tendency. This behavior can be accounted for in terms of a molecular exclusion. It is known that a good linear relationship is obtained between the Freundlich constants log K and 1/N for hydrophobic adsorption. The adsorption of CDs onto AC-A obeyed this relation, but, because of the molecular exclusion, the plots of AC-B deviated greatly. The adsorption of CDs onto AC-A was not explainable in terms of solubility. This could be because, in the case of a solid compound, adsorbability depends on the chemical potential of the molecule in aqueous solution whereas solubility depends also on the heat of fusion of the solid. In order to estimate the relative chemical potential of CDs in water, a method based on the numbers of carbon atoms and oxygen atoms in the molecule was devised which allowed a more accurate estimation of CD adsorbability than did solubility. The mean pore diameter of AC-A increased after CD adsorption, while that of AC-B showed little change. (C) 2000 Academic Press.
  • Characteristics of nonafluorobutyl methyl ether (NFE) adsorption onto activated carbon fibers and different-size-activated carbon particles, S Tanada, N Kawasaki, T Nakamura, M Araki, Y Tachibana, JOURNAL OF COLLOID AND INTERFACE SCIENCE, 228, 2, 220, 225,   2000 08 , 10.1006/jcis.2000.6949, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0034663966&origin=inward
    Summary:The characteristics of adsorption of 1,1,1,2,2,3,3,4,4-nonafluorobutyl methyl ether (NFE), a chlorofluorocarbon (CFC) replacement, onto six different activated carbon; preparations (three activated carbon fibers and three different-sized activated carbon particles) were investigated to evaluate the interaction between activated carbon surfaces and NFE. The amount of NFE adsorbed onto the three activated carbon fibers increased with increasing specific surface area and pore volume. The amount of NFE adsorbed onto the three different-sized-activated carbon particles increased with an increase in the particle diameter of the granular activated carbon. The differential heat of the NFE adsorption onto three activated carbon fibers depended on the porosity structure of the activated carbon fibers. The adsorption rate of NEE was also investigated in order to evaluate the efficiency of NFE recovery by the activated carbon surface. The Sameshima equation was used to obtain the isotherms of NFE adsorption onto the activated carbon fibers and different-sized-activated carbon particles. The rate constant k for NFE adsorption onto activated carbon fibers was larger for increased specific surface area and pore volume. The rate of NFE adsorption on activated carbons of three different particle sizes decreased with increasing particle diameter at a low initial pressure. The adsorption isotherms of NFE for the six activated carbons conformed to the Dubinin-Radushkevich equation; the constants BE0 (the affinity between adsorbate and adsorbent) and W-0 (the adsorption capacity) were calculated. These results indicated that the interaction between the activated carbon and NFE was larger with the smaller specific surface area of the activated carbon fibers and with the smaller particle diameter of the different-sized-activated carbon particles. The degree of packing of NFE in the pores of the activated carbon fibers was greater than that in the pores of the granular activated carbons. (C) 2000 Academic Press.
  • Reduction of iron(III) ion by activated carbon fiber, M Uchida, O Shinohara, S Ito, N Kawasaki, T Nakamura, S Tanada, JOURNAL OF COLLOID AND INTERFACE SCIENCE, 224, 2, 347, 350,   2000 04 , 10.1006/jcis.2000.6713, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0034655239&origin=inward
    Summary:The mechanisms of adsorption of iron(II) ion, iron(III) ion, and reduced iron(III) ion onto an activated carbon fiber and the ability of carbon fibers to reduce iron(III) ion were investigated on the basis of the amounts of iron ion adsorbed. The amount of iron(II) ion adsorbed onto the activated carbon fiber increased with increasing adsorption temperature. Iron(II) ion was more easily removed by the activated carbon fiber than iron(III) ion, Iron(III) ion was adsorbed onto the activated carbon fiber after being reduced to iron(II) ion. The reduction ability of A-20 was stronger than that of A-10 because the hydrophilic groups of A-20 were larger than those of A-10. It is concluded that the activated carbon fiber has a reduction effect on iron(III) ion and that the reduction effect of the activated carbon fiber depended on the number of hydrophilic groups on the activated carbon fiber. (C) 2000 Academic Press.
  • Study of Production of Rubber with Carbon Materials Produced from Organic By-products, Ikuo ABE, Naohito KAWASAKI, Takeo NAKAMURA, Takeshi KONDO, Seiki TANADA, Environmental Science, 13, 2, 235, 238,   2000 , 10.11353/sesj1988.13.235
  • Advanced adsorption of humic acid for trihalomethanes control, M Uchida, S Ito, S Tanada, N Kawasaki, T Nakamura, JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART A-TOXIC/HAZARDOUS SUBSTANCES & ENVIRONMENTAL ENGINEERING, 35, 2, 245, 251,   2000 , http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0034142149&origin=inward
    Summary:For advanced trihalomethanes control, the removal of humic acid, which is one of trihalomethanes precursors, was investigated. The smaller the particle size of activated carbon, the more humic acid was adsorbed. It will be presumed that the contact surface area dominates the amount of humic acid adsorbed. Moreover, the humic acid solution was treated with ozone, and the adsorption removal by activated carbon was investigated. The amount of humic acid adsorbed increased with ozonization time. It is assumed that degradation to lower molecular weight fragments by ozonolysis contributed to the increase in the amount adsorbed onto activated carbon. It was concluded that preozonation was effective in removing humic acid.
  • Competitive adsorption of chloroform and iron ion onto activated carbon fiber, M Uchida, S Ito, N Kawasaki, T Nakamura, S Tanada, JOURNAL OF COLLOID AND INTERFACE SCIENCE, 220, 2, 406, 409,   1999 12 , 10.1006/jcis.1999.6519, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0033572209&origin=inward
    Summary:Chloroform in tap water has been a significant problem because it may be a carcinogenic substituent. Iron ion exists in tap water because of dissolution from iron water pipes. Iron ions in tap water cause discoloration and a bad odor. The isotherms of chloroform and iron ion adsorption onto activated carbon fibers in a single solution (chloroform or iron ion) and in a binary mixture solution (chloroform and iron ion) were investigated to estimate the competitiveness between chloroform and iron ions. The amount of adsorbed iron ions increased with increasing pore volume of the activated carbon fibers, while that of chloroform decreased. The amount of chloroform adsorbed onto the activated carbon fibers in the binary mixture solution was greater than that in the single solution. These results indicate that the adsorption of chloroform and iron ion onto activated carbon fibers could be competitive. (C) 1999 Academic Press.
  • Removal of aromatic hydrocarbon compounds by hydroxypropyl-cyclodextrin, S Tanada, T Nakamura, N Kawasaki, Y Torii, S Kitayama, JOURNAL OF COLLOID AND INTERFACE SCIENCE, 217, 2, 417, 419,   1999 09 , 10.1006/jcis.1999.6350, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0033567467&origin=inward
    Summary:Activated carbon has been used for the recovery and removal of benzene, toluene, and xylenes in air and water for a long time. However, removal of benzene, toluene, and xylenes from soil is very difficult. They can be removed by an increase in the apparent solubility of organic compounds in soil. The apparent solubilities of benzene, toluene, and xylene were investigated to estimate their inclusion behavior into natural cyclodextrins (CDs) and hydroxypropyl-cyclodextrins (HP-CDs) in the liquid phase. The apparent solubilities of benzene, toluene, and xylenes did not increase by adding natural CDs but did increase when HP-CDs were added. Benzene, toluene, and xylenes in a HP-CD solution depended on the relationship between the molecular diameter of benzene, toluene, and xylenes, the CD cavity size, and the l-octanol-water partition coefficient. That of p-xylene was larger than that of o-xylene and m-xylene because of the smallest steric hindrance of p-xylene. (C) 1999 Academic Press.
  • Removal of formaldehyde by activated carbons containing amino groups, S Tanada, N Kawasaki, T Nakamura, M Araki, M Isomura, JOURNAL OF COLLOID AND INTERFACE SCIENCE, 214, 1, 106, 108,   1999 06 , 10.1006/jcis.1999.6176, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0033150829&origin=inward
    Summary:Formaldehyde has been used for disinfection and antisepsis in hospitals due to its bactericidal action, but it is toxic to humans. Hence, we developed adsorbates for the removal of formaldehyde. The adsorbate was prepared by the amination of an activated carbon surface. The removal efficiency and the adsorption mechanism of formaldehyde onto the aminated activated carbon were studied. The concentrated sulfuric acid and nitric acid treatment introduced nitro groups onto the surface of the activated carbon. The nitro groups were reduced by the reaction of powdered iron and hydrochloric acid to the amino groups. The amount of formaldehyde adsorbed onto the activated carbon increased with the amination of the activated carbon because of the increasing interaction between the surface of the activated carbon and the formaldehyde. (C) 1999 Academic Press.
  • Adsorption Removal of Paraquat and Diquat onto Acitvated Carbon at Different Adsorption Temperature, Toxicological and Environmental Chemistry, 70, 275,   1999
  • Recovery Efficiency of the Hydrofluorocarbon(HFC-134a)by Activated Carbons of Different Physicochmical Properties, Toxicological and Environmental Chemistry, 69, 3/4, 449, 458,   1999 , 10.1080/02772249909358724
  • Adsorption Properties of Nonylphenol and Bisphenol A onto Acitvated Carbons, TANSO, 184, 234,   1998
  • Adsorption characteristics of trihalomethanes onto activated carbon fiber from quarternary mixture solution, M Uchida, T Nakamura, N Kawasaki, S Tanada, BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY, 59, 6, 935, 940,   1997 12 , 10.1007/s001289900572, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0030609778&origin=inward
  • Adsorption mechanisms of pentafluoropropanol (5FP) onto activated carbons produced by tetraethoxysilane sol-gel method, N Kawasaki, S Tanada, T Nakamura, T Ohue, Abe, I, JOURNAL OF COLLOID AND INTERFACE SCIENCE, 195, 1, 164, 168,   1997 11 , 10.1006/jcis.1997.5161, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0031279107&origin=inward
    Summary:2,2,3,3,3-Pentafluoro-1-propanol (5FP) has been considered a viable CFC replacement compound. However, 5FP must be recovered in order to decrease the environmental impact and save energy. Activated carbons have been used for the recovery and removal of organic solvents. From the point of view of "zero emission," 5FP and activated carbon must be completely recycled. The purpose of this study is to recycle the activated carbons and to increase the recovery efficiency of 5FP using the activated carbons (ST-ACs) which were coated with tetraethoxysilane by the sol-gel method. The amount of 5FP adsorbed onto the ST-ACs and the degree of 5FP decomposition by the ST-ACs were measured in order to estimate the relationship between the ST-AC surface and 5FP. The amount of 5FP adsorbed and the degree of 5FP decomposition indicated that the recovery of 5FP is suitable for the use with the ST-ACs. (C) 1997 Academic Press.
  • Adsorbability of 1,1,1,2-tetrafluoromethane (HFC134a) onto plasma-treated activated carbon in CF4 and CCl4, S Tanada, N Kawasaki, T Nakamura, T Ohue, Abe, I, JOURNAL OF COLLOID AND INTERFACE SCIENCE, 191, 2, 337, 340,   1997 07 , 10.1006/jcis.1997.4965, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0031571151&origin=inward
    Summary:The adsorbability of 1,1,1,2-tetrafluoroethane (HFC134a), which has been the CFC12 replacement, onto tetrafluoromethane and tetrachloromethane plasma-treated activated carbon (FT-ACs and CT-ACs) was investigated. It is proved that the fluorine and the chlorine, which were produced by plasma treatment, were introduced into the pores having radii greater 7.5 Angstrom and with less than 7.5 Angstrom by plasma treatment, respectively. The adsorption site of HFC134a onto activated carbon may change with the quantities of fluorine or chlorine on the surface of the activated carbon. The amount of HFC134a adsorbed per unit specific surface area of FT-ACs and CT-ACs slightly increased a little compared to the untreated activated carbon (U-AC). The amount of fluoride ion eluted before the adsorption of HFC134a from the FT-ACs increased with the increasing plasma treatment time. That after the adsorption of HFC134a from only the activated carbon with the shortest plasma treatment time decreased. The amount of chloride ion eluted before the adsorption of HFC134a from the CT-ACs increased after 15 min of plasma treatment, but decreased with 30 min of plasma treatment. The chloride ion amount from the CT-ACs decreased after the adsorption of HCF134a. These results could be explained by the Langmuir constants a and Ws, which represent the adsorption equilibrium constant and the saturated amount of HFC134a adsorbed, respectively. The ratio of fluorine and chlorine species, the adsorption type, the layer interstitial type, and the covalent type, is different based on the plasma treatment time. It is concluded that the amount of HFC134a adsorbed onto the FT-ACs and CT-ACs did not depend upon the change of pore structure by the fluorine and chlorine. (C) 1997 Academic Press.
  • Ozone degradation by fluoride onto plasma-treated activated carbon in CF4, S Tanada, N Kawasaki, T Nakamura, T Ohue, Y Torii, JOURNAL OF COLLOID AND INTERFACE SCIENCE, 190, 2, 485, 487,   1997 06 , 10.1006/jcis.1997.4902, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0031570656&origin=inward
    Summary:The ozone degradation of fluorine was investigated using the tetrafluoromethane plasma-treated activated carbon (PT-AC). The ozone in the stratosphere has been degraded by the chloride and bromide radicals which are produced from chlorofluorocarbons and bromofluorocarbons, respectively. However, we believe that fluorine also was related to the ozone degradation. The fluoride was introduced onto the activated carbon surface by tetrafluoromethane plasma treatment. The breakthrough curve of ozone onto PT-AC was measured to elucidate the relationship between the ozone and the fluoride. The amount of ozone adsorbed/degraded onto the PT-AC was larger than the amount that was adsorbed/degraded onto the untreated activated carbon. The amount of fluoride ion eluted from the PT-AC before the adsorption/degradation of ozone was larger than that which eluted after the adsorption/degradation of ozone. These results indicated that the ozone was degraded by the fluoride on the PT-AC surface. (C) 1997 Academic Press.
  • Water sorption characteristics based on amino acid compositions of alkali-processed collagen fiber, K Boki, N Kawasaki, H Takahashi, K Minami, YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 117, 4, 248, 251,   1997 04 , 10.1248/yakushi1947.117.4_248, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0030922342&origin=inward
    Summary:Experimentally measured water vapor sorption isotherms (Sie) of alkali-processed collagen fibers C-20 and C-30 were compared with the theoretical isotherms (Sit) to elucidate the change of the microporous structure caused by the alkali-treatment during 20 and 30 d. The amino acid compositions of the collagen fibers were analyzed, then Sits were calculated from multiplying the degree of hydrophilicity of the sorption site. The amounts of sorbed water of SIe were greater than those of SI in the range of the water activity higher than 13%. The great difference was observed at C-20 rather than C-30. The difference between Sie and SIt was attributed to the large amount of sorbed water in the micropores. This result confirms that the change of collagen fiber during alkali process is explained by the microporous structure, not by the stability of the triple-helix structure.
  • Inclusion of volatile organic compounds into natural cyclodextrins and their branched cyclodextrins in the gaseous phase, S Tanada, T Nakamura, N Kawasaki, S Kitayama, Y Takebe, JOURNAL OF COLLOID AND INTERFACE SCIENCE, 186, 1, 180, 184,   1997 02 , 10.1006/jcis.1996.4627, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0031075429&origin=inward
    Summary:The adsorption isotherms of water, the differential heat of adsorption, and the entropy of adsorbed water were investigated to elucidate the structure of stability of cyclodextrins (CyD) and branched CyD's. The amount adsorbed on branched CyD's increased with increasing relative humidity. The steep rise in the amount adsorbed at higher relative humidities indicated that the structure of branched CyD's was affected by the water molecules at these higher relative humidities. The bonding force between alpha-CyD's and water molecules was stronger than that between their branched CyD's and water, while that between beta-CyD's and water was weaker than that between their branched CyD's and water. We have used activated carbons for the recovery of organic solvents. There are polar groups on the activated carbon surface. Therefore, the recovered organic solvents were degraded by these groups. However, such polar groups are not expected for the hydroxyl groups of the CyD's. The amounts of 1,1,1-trichloroethane, benzene, and toluene included in natural CyD's and their branched CyD's were measured. The amounts of organic solvents included in the CyD's depended upon the cavity radii and the glycosyl and maltosyl functional groups of the CyD's and the radii of the organic solvent molecules. (C) 1997 Academic Press
  • Adsorption of inhalational anesthetics and hydrochlorofluorocarbons on activated carbons as a biological model, S Tanada, N Kawasaki, T Nakamura, Abe, I, CHEMICAL & PHARMACEUTICAL BULLETIN, 45, 2, 231, 235,   1997 02 , http://ci.nii.ac.jp/naid/130003773688
    Summary:Chlorofluorocarbon (CFC) replacements have recently been used for their lower stability and because they have carbon-hydrogen bonds, which means that their atmospheric lifetime is expected to be much shorter than those of CFCs., The adsorption properties of 1,1,2-trichloro-1,2,2-trifluoroethane (CFC113) and its replacement compounds, 1,1-dichloro-2,2,2-trifluoroethane (HCFC123), 1,1-dichloro-1-fluoroethane (HCFC141b), and 1,1-dichloro-1,2,2,3,3-pentafluoropropane (HCFC225ca) on four kinds of activated carbons were investigated, The amount of CFC and HCFCs adsorbed on the activated carbon was concluded to depend upon the number of chloride and carbon atoms in their molecules, The adsorption isotherms of inhalational anesthetics (halothane, chloroform, enflurane, isoflurane, and methoxyflurane) on the activated carbon were measured to evaluate the action mechanism of inhalational anesthesia, The adsorption isotherms of CFC, HCFC, and the inhalational anesthetics were fitted to the Freundlich equation, The Freundlich constant N was well correlated with the minimum alveolar concentration (MAC) of the inhalational anesthetic: 1 MAC means that 50% of the patients will not move during a surgical operation, The adsorption mechanism of inhalational anesthetics on the surface of the activated carbon is concluded to be similar to the adsorption mechanism on a nerve cell, The anesthesia of CFC replacements can be estimated by the Freundlich constant N of the adsorption isotherms.
  • Chloroform removal by surface-modified activated carbon, S Tanada, M Uchida, T Nakamura, N Kawasaki, H Doi, Y Takebe, JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART A-ENVIRONMENTAL SCIENCE AND ENGINEERING & TOXIC AND HAZARDOUS SUBSTANCE CONTROL, 32, 5, 1451, 1458,   1997 , http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0031149289&origin=inward
    Summary:Chloroform as a carcinogen removal by surface-modified activated carbon from an aqueous solution was investigated for the assurance of safe water. Surface hydrophobilized activated carbon by hydrogen gas adsorbed the largest amount of chloroform, To elucidate the dominant factor of adsorption removal of chloroform, correlations between the amount adsorbed and physicochemical properties of adsorbents. A significant inverse correlation was recognized between the amount of chloroform adsorbed and the base consumption. It was found that the existence of acidic groups on the surface of activated carbon inhibits the adsorption of chloroform. It was concluded that the suitable adsorbent for chloroform removal was nn activated carbon with more hydrophobic surface.
  • Adsorption properties of CFC and CFC replacements on activated carbon containing introduced ionic fluoride and chloride, S Tanada, N Kawasaki, T Nakamura, Abe, I, JOURNAL OF COLLOID AND INTERFACE SCIENCE, 183, 1, 143, 147,   1996 10 , 10.1006/jcis.1996.0528, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0030588173&origin=inward
    Summary:Plasma technology has been available for the chlorofluorocarbon (CFC) decomposition or etching of silicone, The adsorption properties of CFC (CFC113) and CFC replacements (HCFC141b, HCFC225cb, and 5FP) on several kinds of plasma-treated activated carbons (P-ACs) prepared under different treatment gases were investigated using the adsorption isotherms, the limiting pore volume (W-o) and the affinity coefficient and energy of adsorption (BE(o)) calculated by the Dubinin-Radushkevich plot, and the quality and kinds of introduced fluoride and chloride, The dissolved fluoride and chloride atoms were introduced to the surface of activated carbon by CFC113, HCFC141b, and HCFC225cb, while the dissolved fluoride atoms were those from 5FP and tetrafluoromethane, The adsorbed amount of CFC and CFC replacements, except for 5FP, on P-ACs was larger than that on U-AC, The specific adsorption site on plasma-treated activated carbon of the CFC and CFC replacements was the fluoride atoms which were introduced by plasma treatment. It is concluded that the plasma-treated activated carbon was suitable for the recovery of CFC and CFC replacements, because the adsorbed amount of CFC and CFC replacements was larger than that on untreated activated carbon, and the adsorbed CFC and CFC replacements on activated carbon were decomposed by the plasma treatment. (C) 1996 Academic Press, Inc.
  • Decomposition degree of chlorofluorocarbon (CFC) and CFC replacements during recovery with surface-modified activated carbon, S Tanada, N Kawasaki, T Nakamura, Abe, I, JOURNAL OF COLLOID AND INTERFACE SCIENCE, 177, 2, 329, 334,   1996 02 , 10.1006/jcis.1996.0039
    Summary:The recovery efficiency of 1,1,2-trichloro-1,2,2-trifluoroethane (CFC113) and three CFC replacements (1,1-dichloro-1-fluoroethane, HCFC141b; 1,3-dichloro-1,1,2,2,3-pentafluoro-propane, HCFC225cb; and 2,2,3,3,3-pentafluoro-1-propanol, 5FP) were investigated on the basis of their degree of decomposition and adsorption isotherms, We prepared activated carbons with various surface polarities to elucidate the recovery efficiency, the amount adsorbed, and the degree of decomposition, A correlation between the physicochemical properties of the activated carbon surface and the amount of CFC or CFC replacements adsorbed was not observed, The amount of CFC113 adsorbed onto untreated activated carbon was the largest of all. That of HCFC225cb adsorbed onto activated carbon treated with hydrogen gas was larger than that adsorbed onto untreated activated carbon and activated carbon treated with 6 N nitric acid, The amount of 5FP and HCFC141b adsorbed on the various activated carbons was not substantial, The degree of decomposition of CFC replacements using the untreated activated carbon except for HCFC225cb was the largest of all. In the case without the activated carbon, that of CFC and the CFC replacements increased in the order 5FP, CFC113 or HCFC225cb, and HCFC141b, These results indicated that the stability of CFC and CFC replacements molecules was controlled by the number of carbon-fluoride groups and/or hydrogen atoms, It is concluded that the recovery of CFC replacements was possible using the surface-modified activated carbons rather than the untreated activated carbon. The degree of decomposition of the CFC replacements during recovery using the activated carbon depends on the relationship between the adsorption site of the surface of the activated carbon and the polarity, hydrophilic site, or hydrophobic site of the CFC replacement molecule. It is assumed that the recovery of CFC replacements using HT-AC decreased the amount of hydrofluoric acid produced. (C) 1996 Academic Press, Inc.
  • Decomposition degree of chlorofluorocarbon (CFC) and CFC replacements during recovery with surface-modified activated carbon, S Tanada, N Kawasaki, T Nakamura, Abe, I, JOURNAL OF COLLOID AND INTERFACE SCIENCE, 177, 2, 329, 334,   1996 02 , 10.1006/jcis.1996.0039, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0029969935&origin=inward
    Summary:The recovery efficiency of 1,1,2-trichloro-1,2,2-trifluoroethane (CFC113) and three CFC replacements (1,1-dichloro-1-fluoroethane, HCFC141b; 1,3-dichloro-1,1,2,2,3-pentafluoro-propane, HCFC225cb; and 2,2,3,3,3-pentafluoro-1-propanol, 5FP) were investigated on the basis of their degree of decomposition and adsorption isotherms, We prepared activated carbons with various surface polarities to elucidate the recovery efficiency, the amount adsorbed, and the degree of decomposition, A correlation between the physicochemical properties of the activated carbon surface and the amount of CFC or CFC replacements adsorbed was not observed, The amount of CFC113 adsorbed onto untreated activated carbon was the largest of all. That of HCFC225cb adsorbed onto activated carbon treated with hydrogen gas was larger than that adsorbed onto untreated activated carbon and activated carbon treated with 6 N nitric acid, The amount of 5FP and HCFC141b adsorbed on the various activated carbons was not substantial, The degree of decomposition of CFC replacements using the untreated activated carbon except for HCFC225cb was the largest of all. In the case without the activated carbon, that of CFC and the CFC replacements increased in the order 5FP, CFC113 or HCFC225cb, and HCFC141b, These results indicated that the stability of CFC and CFC replacements molecules was controlled by the number of carbon-fluoride groups and/or hydrogen atoms, It is concluded that the recovery of CFC replacements was possible using the surface-modified activated carbons rather than the untreated activated carbon. The degree of decomposition of the CFC replacements during recovery using the activated carbon depends on the relationship between the adsorption site of the surface of the activated carbon and the polarity, hydrophilic site, or hydrophobic site of the CFC replacement molecule. It is assumed that the recovery of CFC replacements using HT-AC decreased the amount of hydrofluoric acid produced. (C) 1996 Academic Press, Inc.
  • Sensory Taste Evaluation of Milled Rice Cooked with Water Different in Hordness, Japanese Journal of Food Chemistry, 3, 2, 141,   1996
  • Adsorption of Diquat by Actirated Carbon Fiber, Japanes Journal of Clinical Ecology, 5, 1, 18,   1996
  • EFFECT OF VARIOUS FLUORIDE ATOM SPECIES OF ACTIVATED CARBON IN CF4 PLASMA ON RECOVERY OF TRICHLOROETHYLENE, S TANADA, T NAKAMURA, N KAWASAKI, A IWAKI, Y TORII, CHEMISTRY LETTERS, 773-, 9, 773, 774,   1995 09 , 10.1246/cl.1995.773
    Summary:The surface modification of activated carbon using low temperature plasma of tetrafluoromethane was investigated to evaluate the removal of trichloroethylene. The plasma-treated, activated carbon underwent an immersion water and/or heat-treatment. The adsorption isotherms of trichloroethylene onto the activated carbons were measured to elucidate the relationship between the adsorption behavior of trichloroethylene and the introduced fluoride atoms. The trichloroethylene adsorption sites on plasma-treated, activated carbon are related to the fluoride atom species of the adsorption type, that is, the ion type.
  • EFFECT OF VARIOUS FLUORIDE ATOM SPECIES OF ACTIVATED CARBON IN CF4 PLASMA ON RECOVERY OF TRICHLOROETHYLENE, S TANADA, T NAKAMURA, N KAWASAKI, A IWAKI, Y TORII, CHEMISTRY LETTERS, 1995, 9, 773, 774,   1995 09 , http://ci.nii.ac.jp/naid/10006901538
    Summary:The surface modification of activated carbon using low temperature plasma of tetrafluoromethane was investigated to evaluate the removal of trichloroethylene. The plasma-treated, activated carbon underwent an immersion water and/or heat-treatment. The adsorption isotherms of trichloroethylene onto the activated carbons were measured to elucidate the relationship between the adsorption behavior of trichloroethylene and the introduced fluoride atoms. The trichloroethylene adsorption sites on plasma-treated, activated carbon are related to the fluoride atom species of the adsorption type, that is, the ion type.
  • EFFECT OF VARIOUS FLUORIDE ATOM SPECIES OF ACTIVATED CARBON IN CF4 PLASMA ON RECOVERY OF TRICHLOROETHYLENE, S TANADA, T NAKAMURA, N KAWASAKI, A IWAKI, Y TORII, CHEMISTRY LETTERS, 24, 9, 773, 774,   1995 09 , http://ci.nii.ac.jp/naid/130004419940
    Summary:The surface modification of activated carbon using low temperature plasma of tetrafluoromethane was investigated to evaluate the removal of trichloroethylene. The plasma-treated, activated carbon underwent an immersion water and/or heat-treatment. The adsorption isotherms of trichloroethylene onto the activated carbons were measured to elucidate the relationship between the adsorption behavior of trichloroethylene and the introduced fluoride atoms. The trichloroethylene adsorption sites on plasma-treated, activated carbon are related to the fluoride atom species of the adsorption type, that is, the ion type.
  • CHANGE IN THE POROUS STRUCTURE OF COLLAGEN-FIBERS PREPARED IN ACIDIC PH SOLUTION, K BOKI, N KAWASAKI, T TAMURA, JOURNAL OF COLLOID AND INTERFACE SCIENCE, 173, 1, 249, 250,   1995 07 , 10.1006/jcis.1995.1321, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0007754061&origin=inward
    Summary:Pore size distributions of acid collagen fibers were calculated by the micropore method and the Dollimore-Heal method from the adsorption isotherm of nitrogen in order to elucidate the change in pore volume through acidifying the alkali-processed collagen fiber, The micropores with radii of 12 Angstrom or larger appeared after acidifying the raw collagen fiber C-O with pore radii larger than 20 Angstrom. Increases in pore volume were greater within radii of 12-15.5 or 15.5-24.5 Angstrom rather than within radii of 24.5-95 Angstrom. It was suggested that the interspaces of the triple helix or microfibril within the raw collagen fiber or alkali-processed collagen fibers were increased due to the formation of carboxylic acid moieties during acid preparation. (C) 1995 Academic Press, Inc .
  • THE RECOVERY OF CHLOROFLUOROCARBONS AND CHLOROFLUOROCARBON REPLACEMENTS BY SURFACE-MODIFIED ACTIVATED CARBON, N KAWASAKI, S TANADA, T NAKAMURA, ABE, I, JOURNAL OF COLLOID AND INTERFACE SCIENCE, 172, 2, 368, 373,   1995 06 , 10.1006/jcis.1995.1266, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0001514846&origin=inward
    Summary:The adsorption properties of chlorofluorocarbon CFC113 and CFC replacements (HCFC225cb and 5FP) on activated carbon treated with 6 N nitric acid or hydrogen gas were investigated on the basis of their physicochemical adsorption isotherm and Dubinin-Rudshkevich plot to elucidate the difference between untreated activated carbon (U-AC) and surface modified activated carbon (NT-AC and HT-AC) during interaction with CFCs and CFC replacements. No correlation between the physicochemical properties of the activated carbon surface and the polarity of CFCs or CFC replacements was observed. The adsorption isotherms of CFC113, HCFC225cb, and 5FP on U-AC, NT-AC, and HT-AC have different branch points, that is, selective adsorption (HT-AC) and nonselective adsorption (NT-AC). NT-AC is well suited for the recovery of a mixture of CFCs and CFC replacements, while HT-AC is good for a sample of CFC replacements. Studying the adsorption rate is useful for increasing the recovery efficiency. Therefore, the rate of adsorption of CFCs and CFC replacements onto surface modified activated carbon was investigated. The Sameshima equation fits the adsorption isotherms. The initial rate constants k for CFC113, HCFC225cb, and 5FP onto U-AC, HT-AC, and HT-AC, respectively, were the largest. HT-AC could be adapted for the recovery of HCFC225cb and 5FP. (C) 1995 Academic Press, Inc.
  • DECOMPOSITION DEGREE OF CHLOROFLUOROCARBON AND HYDROCHLOROFLUOROCARBON, S TANADA, N KAWASAKI, T NAKAMURA, ABE, I, CHEMISTRY LETTERS, 1995, 2, 143, 144,   1995 02 , 10.1246/cl.1995.143, http://ci.nii.ac.jp/naid/10006897428
    Summary:Hydrochlorofluorocarbons (HCFCs), which have a smaller ozone depleting propensity than the chlorofluorocarbons (CFCs) replacements, have been developed and produced. However, HCFCs decompose more readily than CFCs. Studying their decomposition degree is useful for increasing their recovery efficiency and minimizing their environmental impact. It is concluded that the amount of produced heavy metal ions was caused by a variation in the pH due to the HF and HCl, and the recovery of HCFC14lb is more difficult than CFCl13 or HCFC123.
  • Chage in the porous structure of collagen Fibers Prepared in Acidic pH Solution, Journal of colloid and Interface Science, 173、249,   1995 , 10.1006/jcis.1995.1321
  • INTERACTION BETWEEN METHYLCHLOROFORM AND SURFACE-MODIFIED ACTIVATED CARBON IN CF4 PLASMA, S TANADA, Y TORII, T NAKAMURA, N KAWASAKI, T TOKIMOTO, CHEMISTRY LETTERS, 1994, 12, 2373, 2376,   1994 12 , 10.1246/cl.1994.2373, http://ci.nii.ac.jp/naid/10006896299
    Summary:The interaction between methylchloroform and a surface modified activated carbon, which was treated with tetrafluoromethane plasma, was evaluated on the basis of adsorption isotherms and physicochemical properties of the activated carbon. Tetrafluoromethane plasma-treated activated carbon could be used for the complete recovery of methylchloroform.
  • STRUCTURAL-ANALYSIS OF PLASMA-TREATED ACTIVATED CARBON USING NITROGEN ADSORPTION METHOD, S TANADA, N KAWASAKI, T NAKAMURA, J IZAWA, Y TORII, JOURNAL OF COLLOID AND INTERFACE SCIENCE, 168, 2, 522, 525,   1994 12 , 10.1006/jcis.1994.1450, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0028695732&origin=inward
    Summary:Nitrogen adsorption isotherms on untreated activated carbon (U-AC) and plasma-treated activated carbons (PT-ACs) with tetrafluoromethane were investigated. The pore volume was calculated using the Dollimore-Heal method from the adsorption isotherms to elucidate the relationship between plasma treatment time and porosity. The total pore volume of pores with radii less than 95 Angstrom decreased with plasma treatment. However, the pore volume of pores with radii less than 7.5 Angstrom was unchanged. This result was explained by the results of the C constant calculated from the BET equation. The pores with radii of 7.5 to 20.5 Angstrom were particularly influenced by the plasma treatment. (C) 1994 Academic Press, Inc.
  • INTERACTION BETWEEN METHYLCHLOROFORM AND SURFACE-MODIFIED ACTIVATED CARBON IN CF4 PLASMA, S TANADA, Y TORII, T NAKAMURA, N KAWASAKI, T TOKIMOTO, CHEMISTRY LETTERS, 23, 12, 2373, 2376,   1994 12 , http://ci.nii.ac.jp/naid/130004419279
    Summary:The interaction between methylchloroform and a surface modified activated carbon, which was treated with tetrafluoromethane plasma, was evaluated on the basis of adsorption isotherms and physicochemical properties of the activated carbon. Tetrafluoromethane plasma-treated activated carbon could be used for the complete recovery of methylchloroform.
  • ADSORPTION CHARACTERISTICS OF TRICHLOROETHYLENE REMOVAL BY 16 KINDS OF GRANULAR ACTIVATED CARBONS IN GASEOUS-PHASE, S TANADA, T NAKAMURA, N KAWASAKI, J IZAWA, T TOKIMOTO, Y TORII, T TAMURA, CHEMICAL & PHARMACEUTICAL BULLETIN, 42, 10, 2146, 2149,   1994 10 , 10.1248/cpb.42.2146, http://ci.nii.ac.jp/naid/110003630798
    Summary:The adsorption characteristics of trichloroethylene (TCE), a major volatile chlorinated hydrocarbon, onto 16 kinds of granular activated carbons (GACs) in gaseous phase were investigated. The amount of TCE adsorbed on GACs was proportional to the pore volume, and the adsorption was recognized to be a physical one. Applying the Dubinin-Radushkevich (D-R) equation to the adsorption isotherms of TCE, GACs could be classified into two types: the D-R plot was either a straight line or not depending on pore size distribution. TCE was believed to be adsorbed not only into micropores but also into transitionalpores.
  • ADSORPTION CHARACTERISTICS OF TRICHLOROETHYLENE REMOVAL BY 16 KINDS OF GRANULAR ACTIVATED CARBONS IN GASEOUS-PHASE, S TANADA, T NAKAMURA, N KAWASAKI, J IZAWA, T TOKIMOTO, Y TORII, T TAMURA, CHEMICAL & PHARMACEUTICAL BULLETIN, 42, 10, 2146, 2149,   1994 10 , http://ci.nii.ac.jp/naid/130003772958
    Summary:The adsorption characteristics of trichloroethylene (TCE), a major volatile chlorinated hydrocarbon, onto 16 kinds of granular activated carbons (GACs) in gaseous phase were investigated. The amount of TCE adsorbed on GACs was proportional to the pore volume, and the adsorption was recognized to be a physical one. Applying the Dubinin-Radushkevich (D-R) equation to the adsorption isotherms of TCE, GACs could be classified into two types: the D-R plot was either a straight line or not depending on pore size distribution. TCE was believed to be adsorbed not only into micropores but also into transitionalpores.
  • BLEACHING RAPESEED AND SOYBEAN OILS WITH SYNTHETIC ADSORBENTS AND ATTAPULGITES, K BOKI, H MORI, N KAWASAKI, JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY, 71, 6, 595, 601,   1994 06 , 10.1007/BF02540585, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0028449944&origin=inward
    Summary:Efficiencies of synthetic adsorbents and attapulgites in bleaching alkali-refined rapeseed and soybean oils ranged from 13-53% and 93-97%, respectively. The Freundlich equation was more applicable than the Langmuir equation to the experimental adsorption isotherms of beta-carotene on attapulgites. Bleaching with attapulgites reduced toco pherols by 12.5-29.5% in rapeseed oil and by 18.9-44.8% in soybean oil. Cosmetic-grade attapulgite was superior to the others in bleaching efficiency, equilibrium amount adsorbed and removal of free fatty acids.
  • MOISTURE SORPTION CHARACTERISTICS OF COLLAGEN-FIBERS PREPARED IN DIFFERENT ACIDIC PH SOLUTIONS, K BOKI, N KAWASAKI, JOURNAL OF COLLOID AND INTERFACE SCIENCE, 164, 2, 364, 369,   1994 05 , 10.1006/jcis.1994.1178, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0028425321&origin=inward
    Summary:Moisture sorption isotherms of acid collagen fibers, CSs (pH 2.3-2.9) and CWs (pH 3.7-4.2), prepared from alkali-processed collagen fibers, Cs (pH 5.4-6.2), were measured. The differences in the Cs, CSs, and CWs in moisture content, heat of moisture sorption, entropy change of moisture sorption, and parameter constant value of the Henderson and the Chung and Pfost equations were investigated. At a water activity above approximately 0.3, moisture content increased in the order CSs, CWs, and Cs. The lower order of Cs, CWs, and CSs in heat of sorption at a low moisture content indicated a decrease in linkage force strength between the water molecule and collagen because of a decrease in the change of the carboxyl group due to the preparation at lower pH. The structural stability of CSs toward moisture sorption was less than those of the Cs and CWs. (C) 1994 Academic Press, Inc.
  • Studies on the Urinary Mineral Concentractions in the Old, Bulletin of Pharmaceutical Research and Technology Institute, 3, 78,   1994
  • Adsorption Characteristics of Trichloroethylene on Plasma-Treated Activated Carbon, Toxicological and Environmental Chemistry, 47, 3+4, 213,   1994
  • MOISTURE SORPTION PROPERTIES OF COLLAGENS VARIED IN POLARITY AND POROUS STRUCTURE BY ALKALI-TREATMENT, K BOKI, N KAWASAKI, H TAKAHASHI, JOURNAL OF COLLOID AND INTERFACE SCIENCE, 161, 1, 148, 154,   1993 11 , 10.1006/jcis.1993.1453, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0001087739&origin=inward
    Summary:Moisture sorption properties of steer hide collagen fibers treated with calcium hydroxide were investigated on the basis of sorption isotherm, differential heat of sorption, entropy of moisture sorption, and applicability of isotherm equations to elucidate the difference between untreated and treated collagens in interaction with water molecules. The alkali-treatment resulted in the occurrence of new and more active sorption sites, the increases in both number of free carboxyl and void space of collagen molecules, and also the change to a more disentangled structure. The increase in moisture content and the changes in interactive force between water molecules and various sorption sites of collagens at different ranges of water activity (Aw) were attributed to the changes in number and strength of polar groups and in inner space of collagens due to alkali-treatment. Sorption characteristics of moisture on collagen could well be explained by the strength of interaction of water with collagen and the surface hydrophobicity of collagen. The Henderson and Chung and Pfost equations fitted the moisture sorption isotherms well over a wide Aw range up to 0.90. The large values of constants in the equations to the moisture sorption isotherms of collagens indicated both unstability of the collagen structure to moisture and negative electrification due to polar groups on the surface of collagen. © 1993 Academic Press. All rights reserved.
  • STRUCTURAL-ANALYSIS OF COLLAGEN-FIBERS BY NITROGEN ADSORPTION METHOD, K BOKI, N KAWASAKI, K MINAMI, H TAKAHASHI, JOURNAL OF COLLOID AND INTERFACE SCIENCE, 157, 1, 55, 59,   1993 04 , 10.1006/jcis.1993.1157, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=5744231209&origin=inward
    Summary:Nitrogen adsorption and desorption isotherms on untreated collagen fiber and collagen fibers treated for 10, 20, and 30 days with calcium hydroxide were investigated. Surface area of the untreated collagen fiber was 2.2 m2/g. Pore size distributions of the collagen fibers were calculated by the micropore method and the Dollimore-Heal method from the adsorption isotherms to elucidate the relationship between alkali treatment period and porosity. The differential micropore volumes, with radii of 15.5 to 24.5 Å, and the cumulative pore volumes, with radii larger than 12 Å, of the collagen fibers treated for 20 days were the largest. The result was well explained by the results of the C constant calculated from the BET equation. © 1993 Academic Press. All rights reserved.
  • In Vitro Adsorption of Paraqyat onto Substituted Chitosan Beads, Japanese Journal of Hygiene,   1993 , 10.1265/jjh.48.973
  • ADSORPTION-ISOTHERMS OF PIGMENTS FROM ALKALI-REFINED VEGETABLE-OILS WITH CLAY-MINERALS, K BOKI, M KUBO, N KAWASAKI, H MORI, JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY, 69, 4, 372, 378,   1992 04 , 10.1007/BF02636071
    Summary:Adsorption isotherms of pigments from alkali-refined oils (rapeseed, soybean, wheatgerm, safflower, corn, cottonseed and sunflower) were measured to investigate the applicability of the Langmuir and Freundlich equations and to elucidate the adsorption characteristics of pigments on sepiolites and standard activated clay. The Freundlich equation was more applicable to the experimental adsorption isotherms. The equilibrium amount adsorbed, acidity, pore size distribution and inflection of the Freundlich isotherms could be explained by assuming that pigments were adsorbed on the stronger acid sites in smaller pores at low concentration, and then in the larger ones when the concentration increased. The amount adsorbed increased with a rise in adsorption temperatures from 70 to 110-degrees-C, and the heat of adsorption was below 10 kcal/mol. The results indicate that pigments were physically adsorbed on the acid sites activated at higher adsorption temperatures.
  • ADSORPTION-ISOTHERMS OF PIGMENTS FROM ALKALI-REFINED VEGETABLE-OILS WITH CLAY-MINERALS, K BOKI, M KUBO, N KAWASAKI, H MORI, JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY, 69, 4, 372, 378,   1992 04 , 10.1007/BF02636071, http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=51249167886&origin=inward
    Summary:Adsorption isotherms of pigments from alkali-refined oils (rapeseed, soybean, wheatgerm, safflower, corn, cottonseed and sunflower) were measured to investigate the applicability of the Langmuir and Freundlich equations and to elucidate the adsorption characteristics of pigments on sepiolites and standard activated clay. The Freundlich equation was more applicable to the experimental adsorption isotherms. The equilibrium amount adsorbed, acidity, pore size distribution and inflection of the Freundlich isotherms could be explained by assuming that pigments were adsorbed on the stronger acid sites in smaller pores at low concentration, and then in the larger ones when the concentration increased. The amount adsorbed increased with a rise in adsorption temperatures from 70 to 110-degrees-C, and the heat of adsorption was below 10 kcal/mol. The results indicate that pigments were physically adsorbed on the acid sites activated at higher adsorption temperatures.
  • Adsorption Characteristics of Dizuat onto Activated Carbon from Saline Solution, Toxicological and Environmental Chemistry, 53、153

Research Grants & Projects

  • Development of adsorbents
  • Removal Environmental Hormones onto Inclusion-Adsorption composite
  • Adsorption Characteristics of Chlorinated Hydrocarbons on Plasma-Treated Activated Carbon
  • Studies on Technology for the Recovery of Chlorofluoro Carbon (CFC) Replacements