KINDAI UNIVERSITY


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辻内 俊文ツジウチ トシフミ

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所属部署名理工学部 生命科学科 / 総合理工学研究科
職名教授/学科長
学位博士(医学)
専門分子腫瘍学、病理診断学
ジャンル医療・健康/がん治療
コメンテータガイドhttps://www.kindai.ac.jp/meikan/754-tsujiuchi-toshifumi.html
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Last Updated :2020/11/25

コミュニケーション情報 byコメンテータガイド

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    肺がんや膵がんを代表とする難治性がんの発生・増殖・浸潤・転移に関わる細胞内分子の同定と、それに基づく新しい分子標的療法開発にむけた基礎的研究を行っています。

学歴・経歴

学歴

  •  - 1992年, 奈良県立医科大学, 医学研究科
  •  - 1992年, 奈良県立医科大学

研究活動情報

研究分野

  • ライフサイエンス, 実験病理学
  • ライフサイエンス, 人体病理学

研究キーワード

  • 分子病理学

論文

  • Cooperation of G12/13 and Gi proteins via lysophosphatidic acid receptor-2 (LPA2) signaling enhances cancer cell survival to cisplatin, Minami K, Ueda N, Ishimoto K, Kurisu R, Takamoto M, Ikeda H, Tsujiuchi T, Biochem Biophys Res Commun., Biochem Biophys Res Commun.,   2020年, 査読有り
  • Different effects of lysophosphatidic acid receptor-2 (LPA2) and LPA5 on the regulation of chemoresistance in colon cancer cells, Ishimoto K, Minami A, Minami K, Ueda N, Tsujiuchi T, J Recept Signal Transduct Res, J Recept Signal Transduct Res, 16, 1, 6,   2020年, 査読有り
  • Lysophosphatidic acid receptor-2 (LPA2)-mediated signaling enhances chemoresistance in melanoma cells treated with anticancer drugs, Minami K, Ueda N, Ishimoto K, Tsujiuchi T., MOLECULAR AND CELLULAR BIOCHEMISTRY, MOLECULAR AND CELLULAR BIOCHEMISTRY, 469, 89, 95,   2020年, 査読有り
  • Effects of lysophosphatidic acid (LPA) receptor-2 (LPA2) and LPA3 on the regulation of chemoresistance to anticancer drug in lung cancer cells., Ueda N, Minami K, Ishimoto K, Tsujiuchi T., Cellular Signalling, Cellular Signalling, 69, 109551,   2020年, 査読有り
  • Regulation of cell survival through free fatty acid receptor 1 (FFA1) and FFA4 induced by endothelial cells in osteosarcoma cells., Minami K, Ueda N, Ishimoto K, Tsujiuchi T., J Recept Signal Transduct Res., J Recept Signal Transduct Res., 40, 2, 181, 186,   2020年, 査読有り
  • LPA5-mediated signaling induced by endothelial cells and anticancer drug regulates cellular functions of osteosarcoma cells, Minami K, Ueda N, Ishimoto K, Tsujiuchi T, Exp Cell Res., Exp Cell Res., 388, 111813,   2020年, 査読有り
  • Modulation of chemoresistance by lysophosphatidic acid (LPA) signaling through LPA5 in melanoma cells treated with anticancer drugs, Minami K, Ueda N, Maeda H, Ishimoto K, Otagaki S, Tsujiuchi T, Biochem Biophys Res Commun., Biochem Biophys Res Commun., 517, 359, 363,   2019年, 査読有り
  • Rapid establishment of highly migratory cells from cancer cells for investigating cellular functions, Ishimoto K, Minami K, Otagaki S, Tsujiuchi T, J Recept Signal Transduct Res, J Recept Signal Transduct Res, 39, 194, 198,   2019年, 査読有り
  • Involvement of LPA receptor-5 in the enhancement of cell motile activity by phorbol ester and anticancer drug treatments in melanoma A375 cells., Fukushima K, Takahashi K, Kurokawa A, Ishimoto K, Otagaki S, Minami K, Fukushima N, Honoki K, Tsujiuchi T, Biochem Biophys Res Commun., Biochem Biophys Res Commun., 496, 1, 225, 230,   2018年01月29日, 査読有り
  • Promotion of cell invasive activity through the induction of LPA receptor-1 in pancreatic cancer cells., Fukushima K, Otagaki S, Takahashi K, Minami K, Ishimoto K, Fukushima N, Honoki K, Tsujiuchi T, J Recept Signal Transduct Res., J Recept Signal Transduct Res., 38, 4, 367, 371,   2018年, 査読有り
  • Lysophosphatidic acid receptor-2 (LPA2) and LPA5 regulate cellular functions during tumor progression in fibrosarcoma HT1080 cells., Takahashi K, Minami K, Otagaki S, Ishimoto K, Fukushima K, Fukushima N, Honoki K, Tsujiuchi T, Biochem Biophys Res Commun., Biochem Biophys Res Commun., 503, 2698, 2703,   2018年, 査読有り
  • Induction of GPR40 positively regulates cell motile and growth activities in breast cancer MCF-7 cells, Fukushima K, Takahashi K, Kusaka M, Ishimoto K, Otagaki S, Minami K, Fukushima N, Honoki K, Tsujiuchi T, J Recept Signal Transduct Res, J Recept Signal Transduct Res, 38, 4, 311, 315,   2018年, 査読有り
  • Involvement of FFA1 and FFA4 in the regulation of cellular functions during tumor progression in colon cancer cells., Takahashi K, Fukushima K, Onishi Y, Minami K, Otagaki S, Ishimoto K, Fukushima N, Honoki K, Tsujiuchi T, Exp Cell Res, Exp Cell Res, 369, 54, 60,   2018年, 査読有り
  • Crossroads of hallmarks in aging and cancer: Anti-aging and anti-cancer target pathways can be shared?, Honoki K, Kuniyasu H, Kishi S, Tanaka Y, Tsujiuchi T, Trends Cancer Res, Trends Cancer Res, 11, 41, 59,   2016年, 査読有り
  • Diverse effects of LPA receptors on cell motile activities of cancer cells., Tsujiuchi T, Hirane M, Dong Y, Fukushima N, J Recept Signal Transduct Res, J Recept Signal Transduct Res, 34, 201, 204,   2014年, 査読有り
  • Comparison of gene expression profiling in sarcoma and mesenchymal stem cells identifies tumorigenic pathways in chemically induced rat sarcoma model., Honoki K, Fujii H, Tohma Y, Tsujiuchi T, Kido A, Tsukamoto S, Mori T, Tanaka Y, ISRN Oncol, ISRN Oncol,   2012年, 査読有り
  • The proteinase inhibitor camostat mesilate suppressed pancreatic pain in rodents., Ishikura H, Nishimura S, Matsunami M, Tsujiuchi T, Ishiki T, Sekiguchi F, Naruse M, Nakatani T, Kamanaka Y, Kawabata A, Life Sci, Life Sci, 98, 1318, 1322,   2007年, 査読有り
  • Molecular aspects during multi-step chemical induced carcinogenesis in the lung and pancreas, Tsujiuchi T, Tsutsumi M, Konishi Y, J Toxicol Pathol, J Toxicol Pathol, 16, 133, 138,   2003年, 査読有り
  • Development of hepatocellular adenomas and carcinomas associated with fibrous in C57BL/6J male mice given a choline-deficient, L-amino acid-defined diet, Denda A, Kitayama W, Kishida H, Murata N, Tsutsumi M, Tsujiuchi T, Nakae D, Konishi Y, Jpn J Cancer Res, Jpn J Cancer Res, 93, 125, 132,   2002年, 査読有り
  • Increased susceptibility of poly(ADP-ribose) polymerase-1 knockout mice to nitrosamine carcinogenicity., Tsutsumi M, Masutani M, Nozaki T, Kusuoka O, Tsujiuchi T, Nakagama H, Suzuki H, Konishi Y, Sugimura T, Carcinogenesis, Carcinogenesis, 22, 16, 22,   2001年, 査読有り
  • Isolation and localization of type IIb Na/Pi cotransporter in the development rat lung., Hashimoto M, Wang DY, Kamo T, Zhu Y, Tsujiuchi T, Konishi Y, Tanaka M, Sugimura H, Am J Pathol, Am J Pathol, 157, 21, 27,   2000年, 査読有り
  • Mutations and reduced expression of the transforming growth factor-b receptor II gene in rat lung adenocarcinomas induced by N-nitrosobis (2-hydroxypropyl) amine., Tsujiuchi T, Sasaki Y, Tsutsumi M, Konishi Y, Jpn J Cancer Res, Jpn J Cancer Res, 91, 1090, 1095,   2000年, 査読有り
  • Enhanced expression of tie2, its ligand angiopoietin-1, vascular endothelial factor, and CD31 in human non-small cell lung carcinomas., Takahama M, Tsutsumi M, Tsujiuchi T, Nezu K, Kushibe K, Taniguchi S, Kotake Y, Konishi Y, Clin Cancer Res, Clin Cancer Res, 5, 1506, 1510,   1999年, 査読有り
  • Telomerase activity in experimental animal tumors., Tsujiuchi T, Tsutsumi M, Konishi Y, Exp Toxicol Pathol., Exp Toxicol Pathol., 50,   1998年, 査読有り
  • Inhibitory by green tea extract of diethylnitrosamine- initiated but not a choline deficient, L-amino acid-defined diet- associated development of putative preneoplastic, glutathione S-transferase placental form- positive lesions in rat liver., Tamura K, Nakae D, Horiguchi K, Akai H, Kobayashi Y, Satoh H, Tsujiuchi T, Denda A, Konishi Y, Jpn J Cancer Res, Jpn J Cancer Res, 88, 356, 362,   1997年, 査読有り
  • Increased telomerase activation in human pancreatic duct adenocarcinomas., Tsutsumi M, Tsujiuchi T, Ishikawa O, Majima T, Yoshimoto M, Sasaki Y, Fukuda T, Oohigashi H, Konishi Y, Jpn J Cancer Res, Jpn J Cancer Res, 88, 971, 976,   1997年, 査読有り
  • Mutations of K-ras but not p53 genes in biliary duct and pancreatic duct carcinogenesis induced in hamsters by cholecystoduodenostomy with dissection of the common duct followed by N-nitrosobis (2-oxopropyl) amine., Majima T, Tsujiuchi T, Tsutsumi M, Tsunoda T, Konishi Y, Cancer Lett, Cancer Lett, 118, 47, 53,   1997年, 査読有り
  • Shortend telomere length and increased telomerase activity in hamster pancreatic duct adenocarcinomas and cell lines., Kobitsu K, Tsutsumi M, Tsujiuchi T, Suzuki F, Kido A, Okajima E, Fukuda T, Sakaki T, Konishi Y, Mol Carcinog, Mol Carcinog, 11, 153, 159,   1997年, 査読有り
  • High rates of Ki-ras point mutation in both intra- and extra-hepatic cholangiocarcinomas., Ohashi K, Tsutsumi M, Nakajima Y, Noguchi O, Okita S, Kitada H, Tsujiuchi T, Kobayashi E, Nakano H, Konishi Y, Jpn J Clin Oncol., Jpn J Clin Oncol., 24, 305, 310,   1994年, 査読有り
  • Effects of LPA1 and LPA6 on the regulation of colony formation activity in colon cancer cells treated with anticancer drugs., Takahashi K, Fukushima K, Otagaki S, Ishimoto K, Minami K, Fukushima N, Honoki K, Tsujiuchi T, J Recept Signal Transduct Res., J Recept Signal Transduct Res., 38, 1, 71, 75,   2018年01月02日, 査読有り
  • Involvement of LPA signaling via LPA receptor-2 in the promotion of malignant properties in osteosarcoma cells, Takahashi K, Fukushima K, Tanaka K, Minami K, Ishimoto K, Otagaki S, Fukushima N, Honoki K, Tsujiuchi T, Exp Cell Res, Exp Cell Res, 369, 2, 316, 324,   2018年, 査読有り
  • LPA signaling through LPA receptors regulates cellular functions of endothelial cells treated with anticancer drugs., Mori S, Araki M, Ishii S, Hirane M, Fukushima K, Tomimatsu A, Takahashi K, Fukushima N, Tsujiuchi T, Mol Cell Biochem, Mol Cell Biochem, 408, 1-2, 147, 154,   2015年10月, 査読有り
  • Different roles of GPR120 and GPR40 in the acquisition of malignant properties in pancreatic cancer cells., Fukushima K, Yamasaki E, Ishii S, Tomimatsu A, Takahashi K, Hirane M, Fukushima N, Honoki K, Tsujiuchi T, Biochem Biophys Res Commun., Biochem Biophys Res Commun., 465, 3, 512, 515,   2015年09月, 査読有り
  • Comparative analyses of lysophosphatidic acid receptor-mediated signaling, Fukushima N, Ishii S, Tsujiuchi T, Kagawa N, Katoh K, Cellular and Molecular Life Sciences, Cellular and Molecular Life Sciences, 72, 12, 2377, 2394,   2015年06月, 査読有り
  • Diverse effects of LPA4, LPA5 and LPA6 on the activation of tumor progression in pancreatic cancer cells., Ishii S, Hirane M, Fukushima K, Tomimatsu A, Fukushima N, Tsujiuchi T, Biochem Biophys Res Commun., Biochem Biophys Res Commun., 461, 1, 59, 64,   2015年05月, 査読有り
  • Role of GPR120 in cell motile activity induced by 12-O-tetradecanoylphorbol-13-acetate in liver epithelial WB-F344 cells., Ishii S, Hirane M, Kitamura Y, Mori S, Fukushima N, Honoki K, Tsujiuchi T, Mol Cell Biochem, Mol Cell Biochem, 400, 1-2, 145, 151,   2015年02月, 査読有り
  • Opposite effects of GPR120 and GPR40 on cell motile activity induced by ethionine in liver epithelial cells., Ishii S, Hirane M, Kato S, Fukushima N, Tsujiuchi T, Biochem Biophys Res Commun., Biochem Biophys Res Commun., 456, 1, 135, 138,   2015年01月, 査読有り
  • Ethionine regulates cell motile activity through LPA receptor-3 in liver epithelial WB-F344 cells., Inoue S, Tanabe E, Shibata A, Hirane M, Araki M, Dong Y, Fukushima N, Tsujiuchi T, Mol Cell Biochem, Mol Cell Biochem, 383, 1-2, 173, 177,   2013年11月, 査読有り
  • Inhibitory effects of LPA1 on cell motile activities stimulated by hydrogen peroxide and 2,3-dimethoxy-1,4-naphthoquinone in fibroblast 3T3 cells., Hirane M, Araki M, Dong Y, Honoki K, Fukushima N, Tsujiuchi T, Biochem Biophys Res Commun., Biochem Biophys Res Commun., 441, 1, 47, 52,   2013年11月, 査読有り
  • Downregulation of activation factors of endothelia and fibroblasts via lysophosphatidic acid signaling in a mouse lung cancer LL/2 cell line., Tanabe E, Kitayoshi M, Hirane M, Araki M, Dong Y, Fukushima N, Tsujiuchi T, J Recept Signal Transduct Res, J Recept Signal Transduct Res, 33, 5, 286, 290,   2013年10月, 査読有り
  • Extracellular lipid metabolism influences the survival of ovarian cancer cells, Kuwata S, Ohkubo K, Kumamoto S, Yamaguchi N, Izuka N, Murota K, Tsujiuchi T, Iwamori M, Fukushima N, Biochem. Biophys. Res. Commun., Biochem. Biophys. Res. Commun., 439, 2, 280, 284,   2013年09月, 査読有り
    概要:リゾホスファチジン酸が卵巣がん細胞の細胞死を抑制することを見出した。この作用は細胞外で切断されたオレイン酸によることが分かった。
  • Hydrogen peroxide stimulates cell motile activity through LPA receptor-3 in liver epithelial WB-F344 cells., Shibata A, Tanabe E, Inoue S, Kitayoshi M, Okimoto S, Hirane M, Araki M, Fukushima N, Tsujiuchi T, Biochem Biophys Res Commun., Biochem Biophys Res Commun., 433, 3, 317, 321,   2013年04月12日, 査読有り
  • Lysophosphatidic acid receptor-3 increases tumorigenicity and aggressiveness of rat hepatoma RH7777 cells., Okabe K, Hayashi M, Kato K, Okumura M, Fukui R, Honoki K, Fukushima N, Tsujiuchi T, Mol Carcinog, Mol Carcinog, 52, 4, 247, 254,   2013年04月, 査読有り
  • Involvement of oncogenic K-ras on cell migration stimulated by lysophosphatidic acid receptor-2 in pancreatic cancer cells., Yoshikawa K, Tanabe E, Shibata A, Inoue S, Kitayoshi M, Okimoto S, Fukushima N, Tsujiuchi T, Exp Cell Res, Exp Cell Res, 319, 3, 105, 112,   2013年02月, 査読有り
  • Enhancement of Drug Resistance by Lysophosphatidic Acid Receptor-3 in Mouse Mammary Tumor FM3A Cells., Fukui R, Kato K, Okabe K, Kitayoshi M, Tanabe E, Fukushima N, Tsujiuchi T, Journal of toxicologic pathology, Journal of toxicologic pathology, 25, 3, 225, 228,   2012年, 査読有り
  • No involvement of lysophosphatidic acid receptor-3 in cell migration of mouse lung tumor cells stimulated by 12-O-tetradecanoylphorbol-13-acetate., Okumura M, Kato K, Fukui R, Fukushima N, Tsujiuchi T, J Toxicol Pathol, J Toxicol Pathol, 24, 3, 183, 186,   2011年10月13日, 査読有り
  • Genetic and epigenetic alterations of lysophosphatidic acid receptor genes in rodent tumors by experimental models., Tsujiuchi T, Okabe K, Fukushima N, J Toxicol Pathol, J Toxicol Pathol, 24, 3, 143, 148,   2011年10月13日, 査読有り
  • Mutations of LKB1 gene in pancreatic ductal adenocarcinomas induced by N-nitrosobis(2-oxopropyl)amine in hamsters., Furukawa M, Yamasaki A, Yoshida J, Tsujino M, Wakabayashi N, Honoki K, Tsujiuchi T, Anticancer Res, Anticancer Res, 29, 10, 4047, 4050,   2009年10月, 査読有り
  • Hydrogen sulfide as a novel mediator for pancreatic pain in rodents., Nishimura S, Fukushima O, Ishikura H, Takahashi T, Matsunami M, Tsujiuchi T, Sekiguchi F, Naruse M, Kamanaka Y, Kawabata A, Gut, Gut, 58, 6, 762, 770,   2009年06月, 査読有り
  • Post-translational modifications of tubulin in the nervous system., Fukushima N, Furuta D, Hidaka Y, Moriyama R, Tsujiuchi T, J Neurochem., J Neurochem., 109, 3, 683, 693,   2009年05月, 査読有り
  • Sphere-forming stem-like cell populations with drug resistance in human sarcoma cell lines., Fujii H, Honoki K, Tsujiuchi T, Kido A, Yoshitani K, Takakura Y, Int J Oncol, Int J Oncol, 34, 5, 1381, 1386,   2009年05月, 査読有り
  • Post-trasnlational modification of tubilin in the nervous system, FUKUSHIMA Nobuyuki, FURUTA Daisuke, HIDAKA Yuji, MORIYAMA Ryutaro, TSUJIUCHI Toshifumi, Journal of Neurochemistry, Journal of Neurochemistry, 109, 3, 683, 693,   2009年05月
  • Frequent mutations of lysophosphatidic acid receptor-1 gene in rat liver tumors, Obo Y, Yamada T, Furukawa M, Hotta M, Honoki K, Fukushima N, Tsujiuchi T, Mutat Res, Mutat Res, 660, 1-2, 47, 50,   2009年01月, 査読有り
  • Mutations of lysophosphatidic acid receptor-1 gene during progression of lung tumors in rats., Yamada T, Obo Y, Furukawa M, Hotta M, Yamasaki A, Honoki K, Fukushima N, Tsujiuchi T, Biochem Biophys Res Commun., Biochem Biophys Res Commun., 378, 3, 424, 427,   2009年01月, 査読有り
  • Infrequent mutation of lysophosphatidic acid receptor-1 gene in hamster pancreatic duct adenocarcinomas and established cell lines., Tsujiuchi T, Furukawa M, Obo Y, Yamasaki A, Hotta M, Kusunoki C, Suyama N, Mori T, Honoki K, Fukushima N, J Toxicol Pathol, J Toxicol Pathol, 22, 1, 89, 92,   2009年, 査読有り
  • A lysophosphatidic acid receptor lacking the PDZ-binding domain is constitutively active and stimulates cell proliferation., Shano S, Hatanaka K, Ninose S, Moriyama R, Tsujiuchi T, Fukushima N, Biochim Biophys Acta, Biochim Biophys Acta, 1783, 5, 748, 759,   2008年05月, 査読有り
  • Reduced expression of the Rassf1a gene and its aberrant DNA methylation in pancreatic duct adenocarcinomas induced by N-nitrosobis(2-oxopropyl)amine in hamsters., Shimizu K, Itsuzaki Y, Fujii H, Honoki K, Tsujiuchi T, Mol Carcinog, Mol Carcinog, 47, 2, 80, 87,   2008年02月, 査読有り
  • Numerical changes in the mitochondrial DNA displacement loop in lung lesions induced by N-nitrosobis(2-hydroxypropyl)amine in rats, Onishi M, Saito M, Sokuza Y, Mori C, Nishikawa T, Shimizu K, Sugata E, Tsujiuchi T, Mutat Res, Mutat Res, 638, 1-2, 133, 138,   2008年02月, 査読有り
  • Absence of mitochondrial DNA displacement loop mutations in hamster pancreatic duct adenocarcinomas and established cell lines, Onishi M, Saito M, Sokuza Y, Mori C, Nishikawa T, Mori T, Tsujiuchi T, J Toxicol Patho, J Toxicol Patho, 20, 4, 263, 266,   2008年01月08日, 査読有り
  • Growth inhibition and induction of apoptosis by 2-methoxyestradiol in rat osteosarcoma and malignant fibrous histiocytoma cell lines., Fujii H, Honoki K, Tsujiuchi T, Kido A, Yoshitani K, Takakura Y, In Vivo, In Vivo, 22, 1, 21, 25,   2008年01月, 査読有り
  • Reduced Expression of the Pcdh20 Gene and Its Aberrant DNA Methylation in Lung Adenocarcinomas Induced by N-nitrosobis(2-hydroxypropyl)amine in Rats., Sokuza Y, Yamada T, Obo Y, Furukawa M, Hotta M, Yamasaki A, Honoki K, Tsujiuchi T, J Toxicol Pathol, J Toxicol Pathol, 21, 4, 257, 260,   2008年, 査読有り
  • Aberrant expressions of lysophosphatidic acid receptor genes in lung and liver tumors of rats., Tsujiuchi T, Shimizu K, Onishi M, shigemura M, Shano S, Honoki K, Fukushima N, J Toxicol Pathol, J Toxicol Pathol, 19, 3, 137, 141,   2006年10月10日, 査読有り
  • Possible lack of carcinogenic potential of 9-(4'- aminophenyl)- 9H- pyrido [3,4-b] indole (aminophenylnorharman) for the pancreatic duct epithelium in hamsters., Kubozoe T, Tsutsumi M, Murata N, Tsujiuchi T, Tsunoda T, Sugimura T, Wakabayashi K, Konishi Y, J Toxicol Pathol, J Toxicol Pathol, 15, 1, 7, 12,   2002年, 査読有り
  • FHIT alterations in lung adenocarcinomas induced by N-nitrosobis (2-hydroxypropyl)amine in rats., Tsujiuchi T, Sasaki Y, Murata N, Tsutsumi M, Konishi Y, Nakae D, Carcinogenesis, Carcinogenesis, 22, 12, 2017, 2022,   2001年12月, 査読有り
  • Elevated expression of transforming growth factor beta and the tumor necrosis factor family in lung adenocarcinomas induced by N-nitrosobis (2-hydroxypropyl)amine in rats., Tsujiuchi T, Sasaki Y, Murata N, Tsutsumi M, Nakae D, Konishi Y, Exp Toxcol Pathol, Exp Toxcol Pathol, 53, 4, 291, 295,   2001年09月, 査読有り
  • Absence of beta-catenin gene mutations in pancreatic duct lesions induced by N-nitrosobis(2-oxopropyl)amine in hamsters., Kubozoe T, Tsujiuchi T, Murata N, Sasaki Y, Tsunoda T, Konishi Y, Tsutsumi M, Cancer Lett., Cancer Lett., 168, 1, 1, 6,   2001年07月, 査読有り
  • Absence of PTEN/MMAC1 gene mutations in lung adenocarcinomas induced by N-nitrosobis (2-hydroxypropyl)amine in rats., Tsujiuchi T, Sasaki Y, Tsutsumi M, Konishi Y, Cancer Lett, Cancer Lett, 162, 2, 207, 211,   2001年01月, 査読有り
  • Interleukin-15 expression is associated with malignant potential in colon cancer cells., Kuniyasu H, Oue N, Nakae D, Tsutsumi M, Denda A, Tsujiuchi T, Yokozaki H, Yasui W, Pathobiology, Pathobiology, 69, 2, 86, 95,   2001年, 査読有り
  • Lack of effects of bisphenol A in maternal rats or treatment on response of their offspring to N-nitrosobis (2-hydroxypropyl) amine in rats., Takashima Y, Tsutsumi M, Sasaki Y, Tsujiuchi T, Kusuoka O, Konishi Y, J Toxicol Pathol, J Toxicol Pathol, 14, 2, 87, 98,   2001年, 査読有り
  • Alterations of the transforming growth factor-beta signaling pathway in hepatocellular carcinomas induced endogenously and exogenously in rats., Sasaki Y, Tsujiuchi T, Murata N, Tsutsumi M, Konishi Y, Jpn J Cancer Res., Jpn J Cancer Res., 92, 1, 16, 22,   2001年01月, 査読有り
  • Lack of significant tumor induction by endogenously formed N- nitrosobis (2-hydroxypropyl) amine in rats fed tris (2-hydroxypropyl) amine and sodium nitrite., Yamamoto K, Tsutsumi M, Tsujiuchi T, Kobitsu K, Okajima E, Takahama M, Mori Y, Konishi Y, J Toxicol Pathol, J Toxicol Pathol, 9, 2, 199, 204,   1996年, 査読有り
  • Effects of 3-aminobenzamide on the post-initiation phase of N-nitrosobis(2-oxopropyl)amine induced pancreatic carcinogenesis in Syrian hamsters., Tsujiuchi T, Mizumoto K, Tsutsumi M, Denda A, Amanuma T, Kondoh S, Konishi Y, Cancer Lett., Cancer Lett., 61, 1, 61, 66,   1991年12月, 査読有り
  • Effects of 3-aminobenzamide on induction of multiorgan carcinogenesis by N-nitrosobis(2-hydroxypropyl)amine in hamsters., Tsujiuchi T, Tsutsumi M, Denda A, Amanuma T, Kondoh S, Kamino K, Konishi Y, Jpn J Cancer Res., Jpn J Cancer Res., 82, 7, 793, 799,   1991年07月, 査読有り
  • Effects of catechol and its analogs on pancreatic carcinogenesis initiated by N-nitrosobis(2-oxopropyl)amine in Syrian hamsters., Maruyama H, Amanuma T, Nakae D, Tsutsumi M, Kondo S, Tsujiuchi T, Denda A, Konishi Y, Carcinogenesis, Carcinogenesis, 12, 7, 1331, 1334,   1991年07月, 査読有り
  • Initiating activity of diethylnitrosamine in a rapid production model for pancreatic carcinomas in Syrian hamsters., Amanuma T, Mizumoto K, Tsutsumi M, Tsujiuchi T, Kitazawa S, Hasegawa K, Denda A, Maruyama H, Konishi Y, Jpn J Cancer Res, Jpn J Cancer Res, 82, 6, 632, 637,   1991年06月, 査読有り
  • Induction of 8-hydroxydeoxyguanosine but not initiation of carcinogenesis by redox enzyme modulations with or without menadione in rat liver., Denda A, Sai KM, Tang Q, Tsujiuchi T, Tsutsumi M, Amanuma T, Murata Y, Nakae D, Maruyama H, Kurokawa Y, Carcinogenesis, Carcinogenesis, 12, 4, 719, 726,   1991年04月, 査読有り

書籍等出版物

  • ミネルヴァ書房, 『ケアマネジメント用語辞典(改訂版)』, 南 武志, 吉田 繁, 巽 純子, 辻内 俊文, 和田 哲幸, 今西 孝至, 共著,   2007年
  • ミネルヴァ書房, 『ケアマネジメント用語辞典』, 南 武志, 吉田 繁, 巽 純子, 辻内 俊文, 和田 哲幸, 今西 孝至, 共著,   2005年

講演・口頭発表等

  • 膵炎関連痛モデルにおけるメシル酸カモスタットの抗侵害受容的作用., 西村 幸容, 川畑 篤史, 関口 富美子, 辻内 俊文, 松波 真帆, 第79回日本薬理学会年会,   2010年, 第79回日本薬理学会年会
  • Involvement of endogenous hydrogen sulfide in acute pancreatitis-related pain., 西村 幸容, 川畑 篤史, 辻内 俊文, 関口 富美子, 松波 真帆, 6th FENS Forum of European Neuroscience,   2008年07月, 6th FENS Forum of European Neuroscience
  • Hydrogen sulfide as a nociceptive messenger in rat and mouse pancreata., 川畑 篤史, 関口 富美子, 松波 真帆, 辻内 俊文, 西村 幸容, Neuroscience 2007,   2007年11月, Neuroscience 2007
    概要:4. Kawabata, A., Nishimura, S. 西村幸容, Fukushima, O., Ishikura, H., Takahashi, T., Matsunami, M., Tsujiuchi, T., Sekiguchi, F., Naruse, M., Kamanaka, Y. , 2007, 11, 3-7, Dan Diego, USA.

MISC

  • 培養海馬神経細胞におけるLPA3を介する軸索分岐形成の分子メカニズム(Molecular mechanism of LPA3-Mediated axonal branching formation in cultured hippocampal neurons), 古田 大祐, 山根 昌之, 森山 隆太郎, 藤田 典久, 辻内 俊文, 福嶋 伸之, 日本生化学会大会・日本分子生物学会年会合同大会講演要旨集, 83回・33回, 2P, 0682,   2010年12月
  • LPA3受容体活性化は海馬神経細胞の軸索分岐形成を引き起こす(Lysophosphatidic acid receptor 3 activation induces axonal branch formation in cultured hippocampal neurons), 福嶋 伸之, 古田 大祐, 山根 昌之, 辻内 俊文, 森山 隆太郎, 神経化学, 49, 2-3, 540, 540,   2010年08月
  • 培養海馬ニューロンにおいてリゾホスファチジン酸受容体3は神経突起分枝と関係がある(Lysophosphatidic acid receptor 3 is involved in neurite branching formation in cultured hippocampal neurons), 古田 大祐, 山根 昌之, 森山 隆太郎, 辻内 俊文, 福嶋 伸之, 日本生化学会大会プログラム・講演要旨集, 82回, 4P, 415,   2009年09月
  • ユーイング肉腫細胞株HTB166における化学療法抵抗性幹細胞様細胞の単離(Identification of sphere forming chemo-resistant stem-like cells in human Ewing sarcoma HTB166 cell line), 朴木 寛弥, 藤井 宏真, 城戸 顕, 辻内 俊文, 日本癌学会総会記事, 67回, 329, 329,   2008年09月
  • 骨・軟部腫瘍における分子・細胞標的 ヒト肉腫細胞における腫瘍幹細胞の単離の試み, 藤井 宏真, 朴木 寛弥, 城戸 顕, 芳谷 和洋, 辻内 俊文, 高倉 義典, 日本整形外科学会雑誌, 82, 8, S921, S921,   2008年08月
  • BHPによるラット肺腺癌発生におけるTSLC cascade異常の関与(Involvement of TSLC cascade in the development of rat lung adenocarcinomas by N-nitrosobis(2-hydroxypropyl)amine), 清水 恭子, 藤井 宏真, 朴木 寛弥, 辻内 俊文, 日本癌学会総会記事, 66回, 112, 112,   2007年08月
  • ラット肉腫細胞株における幹細胞様細胞の存在とINK4a-ARF遺伝子発現欠失(Stem-like Subpopulation with Silenced INK4a-ARF Locus Genes in Rat Sarcoma Cell Lines), 朴木 寛弥, 藤井 宏真, 芳谷 和洋, 城戸 顕, 辻内 俊文, 森 俊雄, 日本癌学会総会記事, 66回, 196, 196,   2007年08月
  • Inhibition of pancreatic carcinogenesis by shark cartilage proteoglycan in hamsters, Kitahashi T, Sato K, Oka Y, Tsujiuchi T, Sakamoto A, Mitsui M, Mori T, Nakamura Y, Otsuki K, Tsutsumi M, J toxicol Pathol., 19, 4, 179, 184,   2006年12月15日, 10.1293/tox.19.179

競争的資金

  • 化学発癌機構の解析