松添 弘樹 (マツゾエ ヒロキ)

  • 医学科 医学部講師
Last Updated :2024/04/23

コミュニケーション情報 byコメンテータガイド

  • コメント

    慢性心不全 心エコー図診断 弁膜症 心筋症 構造的心疾患

研究者情報

学位

  • 博士(医学)(2017年03月 神戸大学)

ホームページURL

科研費研究者番号

  • 80991215

ORCID ID

J-Global ID

研究キーワード

  • 循環器内科学   心不全   心臓超音波   心臓弁膜症   心筋症   肺高血圧症   

現在の研究分野(キーワード)

    慢性心不全 心エコー図診断 弁膜症 心筋症 構造的心疾患

研究分野

  • ライフサイエンス / 循環器内科学 / 心臓超音波
  • ライフサイエンス / 循環器内科学 / 心不全
  • ライフサイエンス / 循環器内科学 / 心臓弁膜症
  • ライフサイエンス / 循環器内科学 / 心筋症
  • ライフサイエンス / 循環器内科学 / 肺高血圧症

学歴

  • 2014年04月 - 2017年03月   神戸大学   大学院医学研究科   医科学専攻

研究活動情報

論文

  • Hiroaki Shiraki; Hiroshi Tsunamoto; Tetsuari Onishi; Jun Mukai; Hiroyuki Shimoura; Hiroki Matsuzoe; Fumitaka Soga; Junichi Imanishi; Shun Yokota; Hiroyuki Sano; Yusuke Tanaka; Ken-Ichi Hirata; Hidekazu Tanaka
    Echocardiography (Mount Kisco, N.Y.) 41 1 e15735  2024年01月 

    Objectives

    We previously reported a higher left atrial volume index (LAVI) was independently associated with left atrial (LA) appendage (LAA) thrombus formation in 737 patients with non-valvular atrial fibrillation (NVAF) receiving appropriate oral anticoagulation therapy. Since our previous study was a retrospective single-center study, we designed and conducted a prospective multi-center study to verify our findings for LAVI as a predictor of LAA thrombus in patients with NVAF receiving appropriate oral anticoagulation therapy.

    Methods

    This prospective multi-center study comprised 746 consecutive patients with NVAF recruited between December 2021 and March 2023 from eight institutions in Japan, who were receiving appropriate oral anticoagulation therapy, had undergone transthoracic echocardiography and transesophageal echocardiography (TEE).

    Results

    LAA thrombi were observed in 21 patients (2.8%). The prevalence of LAA thrombus formation in patients with paroxysmal AF (PAF) was significantly lower than that in patients with non-PAF (0.7% vs. 4.1%, p = .006). LAA thrombus formation was detected in none (0/171) of the patients with normal size LA (LAVI ≤ 34 mL/m2 ). The prevalence of LAA thrombus formation in patients with mildly dilated LA (LAVI: 34-49.9 mL/m2 ) was 2.1% (6/283), but that in PAF patients was low at 1.0% (1/104). Furthermore, this prevalence in patients with severely dilated LA (LAVI ≥ 50 mL/m2 ) was high at 5.1% (15/292).

    Conclusions

    The findings of this prospective multi-center study are consistent with those of our previous study. Thus, the need for TEE prior to catheter ablation or electrical cardioversion can be determined by the level of LAVI.
  • Sato Namura; Hiroki Matsuzoe; Mayumi Inaba; Ryo Nishio; Daisuke Matsumoto; Hiroshi Takaishi
    Clinical Case Reports 2023年11月
  • Suehiro W; Nishio R; Noiri JI; Takeshige R; Konishi H; Matsuzoe H; Matsumoto A; Ozawa M; Matsumoto D; Inaba M; Takaishi H
    Journal of cardiology cases 2023年07月 
    Acute myocarditis is a rare complication of Campylobacter jejuni enteritis. Herein, we report the case of a 20-year-old man who presented with chest pain that developed three days after the onset of enteritis. Electrocardiogram, echocardiogram, and cardiac enzyme levels suggested myocarditis. Cardiac magnetic resonance imaging revealed a late gadolinium enhancement in the inferior wall. Degeneration and necrosis of myocardial cells and lymphocyte-dominant inflammatory cell infiltration were found in the tissue obtained by endomyocardial biopsy. Acute myocarditis associated with C. jejuni enteritis was confirmed by these findings and C. jejuni detected in the stool culture. The symptoms of enteritis and myocarditis remitted 10 days after the onset. The left ventricular ejection fraction was improved from 40 % to 57 %.In previous cases, endomyocardial biopsy has not been performed because of mild myocarditis. The lack of pathological reports makes the mechanism of myocarditis associated with C. jejuni enteritis unknown. We report a case of myocarditis associated with C. jejuni enteritis, which was diagnosed using cardiac magnetic resonance imaging and endomyocardial biopsy.

    Learning objective

    Acute myocarditis is a rare but important complication of Campylobacter jejuni enteritis. Cardiac magnetic resonance imaging is useful for diagnosis. Most cases of myocarditis associated with C. jejuni enteritis were mild and remitted without specific treatment. In the present case, endomyocardial biopsy was performed and CD4-positive lymphocytes were predominantly detected in the myocardial tissue.
  • Nao Oda; Hiroki Matsuzoe; Shunsuke Sato; Ryo Nishio; Daisuke Matsumoto; Takashi Azami; Hiroshi Takaishi
    Journal of Echocardiography 2023年05月
  • Jun‐ichi Noiri; Hiroki Konishi; Hiroki Matsuzoe
    Journal of Arrhythmia 39 2 224 - 226 2023年04月 
    Limited studies report on the status of surgical closure patches for atrial septal defect (ASD) in the remote period. In our case, transthoracic echocardiography revealed a fistula of ASD patch before pulmonary vein isolation for atrial fibrillation. Preoperative Imaging examinations aid in evaluating the effect of the needle puncture around the artificial material of the atrial septum and catheter manipulation for patients with a history of ASD closure.
  • Matsuzoe H; Hidekazu Tanaka; Sato S; Otani K
    European heart journal. Case reports 6 12 ytac462  2022年12月 

    Background

    Transthyretin amyloid cardiomyopathy (ATTR-CM) is usually characterized by left ventricular (LV) hypertrophy or LV systolic dysfunction. However, right atrial (RA) amyloidosis without LV hypertrophy, leading to severe functional tricuspid regurgitation (FTR), is extremely rare.

    Case summary

    We present 75-year-old female with exertional dyspnoea and pre-syncope. Transthoracic echocardiography showed a normal LV function and no LV hypertrophy. A sick sinus syndrome and severe FTR due to right ventricular (RV) and RA dilatation were observed. A leadless cardiac pacemaker implantation was performed for sick sinus syndrome and the symptoms improved, but she complained of leg oedema and fatigue on effort again. A repeated transthoracic echocardiogram showed no notable changes in LV function, but progression of RV and RA dilatation was observed, with worsening FTR. Despite treatment of loop diuretics with 30 mg daily of azosemide, symptoms did not improve, and the patient underwent tricuspid valve annuloplasty. Pathological findings from right atrium led to a diagnosis of ATTR-CM, and deoxyribonucleic acid sequence analysis did not indicate any typical mutation, which supported a diagnosis of wild type of ATTR-CM (ATTRwt-CM). She has been asymptomatic after the surgical operation. She has also been treated with 80 mg daily of tafamidis meglumine to prevent further accumulation of transthyretin in the myocardium and potentially improve long-term outcomes.

    Discussion

    Isolated atrial amyloidosis, especially occurring predominantly in the right atrium and caused by ATTRwt-CM without LV hypertrophy, is extremely rare. However, differential diagnosis should be considered for patients with unexplained dilatation of the right-sided heart or bradyarrhythmia.
  • Matsuzoe H; Sato S; Nishio R; Ozawa M; Matsumoto D; Takaishi H
    Journal of cardiology cases 27 2 63 - 66 2022年11月 
    As the clinical manifestations of traumatic tricuspid valve regurgitation vary according to the extent of tricuspid valve injury, this condition can often go unnoticed and be incidentally discovered. Here, we report the case of a 40-year-old man with patent foramen ovale, in which severe tricuspid regurgitation due to tricuspid valve prolapse was incidentally discovered following blunt chest trauma. Further examination revealed that the prolapse had also caused active right ventricular mural infective endocarditis. The patient had no relevant past medical history of chronic debilitating disease or immunosuppression. After evaluation by the cardiology team, emergent surgical tricuspid valvular repair was successfully performed.

    Learning objective

    Tricuspid valve prolapses resulting from chest trauma may occasionally lead to severe tricuspid regurgitation. Furthermore, this may cause active right ventricular infective endocarditis. In the present case, Staphylococcus aureus was detected in blood cultures, which is usually rapidly progressive and often leads to devastating consequences. Early surgical approach should be considered in cases of infection in the left atrium via patent foramen ovale.
  • 下山 由希子; 松添 弘樹; 佐藤 俊輔; 竹重 遼; 小西 弘樹; 松本 晃典; 西尾 亮; 小澤 牧人; 松本 大典; 高石 博史; 莇 隆
    心臓 54 9 1057 - 1064 (公財)日本心臓財団 2022年09月 
    症例は71歳男性。特記すべき通院歴、既往歴なし。約1ヵ月前に他院で肺炎の診断で入院加療を行い、軽快し退院するも、徐々に増悪する全身倦怠感と発熱を主訴に当院救急外来を受診した。胸部単純CTで両側肺野に多発する小浸潤影を認め肺炎の再燃疑いで入院した。血液培養よりメチシリン感受性黄色ブドウ球菌が検出され、心エコー図検査で漏斗部型心室中隔欠損症に加えて、右室流出路に疣贅を疑う像と感染に続発したと思われるValsalva洞の穿孔、肺動脈弁穿孔が疑われた。また左室拡大と軽度から中等度の僧帽弁逆流も認めた。胸部X線画像で肺うっ血を認め右心カテーテル検査で肺体血流比が3.45であるも、肺血管抵抗の著明な上昇はなく体血圧は維持され左心不全症状は軽度であったことから、利尿薬の内服と抗生剤の点滴加療を先行した。第54病日にValsalva洞穿孔部と心室中隔欠損のパッチ閉鎖術および肺動脈弁尖穿孔部の縫合閉鎖術を施行し、術後経過は良好であったため第68病日に自宅退院した。敗血症性肺塞栓症が疑われる場合は、右心系の感染性心内膜炎および背景となる心疾患を疑い、入念に心エコー図検査を行うべきと考える。(著者抄録)
  • Noiri JI; Matsuzoe H; Nagaya S; Nishio R; Matsumoto D; Takaishi H; Morishita E
    Journal of cardiology cases 26 5 360 - 363 2022年08月 
    Hereditary protein C (PC) deficiency is a quantitative or qualitative abnormality of the coagulation regulator PC resulting in a decreased PC activity. It is caused by mutations in the PC gene (PROC) located on chromosome 2q13-q14. Although hereditary PC deficiency is an important risk factor for venous thromboembolism (VTE), it is often overlooked because of difficulties in genetic examination. The low prevalence of this disease has led to a lack of evidence for its treatment. We report the case of a 21-year-old male with VTE caused by hereditary PC deficiency due to a novel PROC gene mutation, c.566G>A, p.Arg 189 Gln. The patient was refractory to treatment with direct oral anticoagulants, but responded to catheter-directed thrombolysis. Further intrafamilial genetic survey revealed the presence of the same mutation in five of the six family members.

    Learning objectives

    Venous thromboembolism (VTE) caused by hereditary protein C deficiency that is refractory to direct oral anticoagulants may respond to catheter-directed thrombolysis. Furthermore, the first VTE in young patients with a strong family history and female family members of childbearing age should be considered for genetic testing. In addition, genetic examination will help establish evidence for the treatment of such patients.
  • Noiri JI; Konishi H; Matsuzoe H; Sato S; Azami T; Teramura K
    HeartRhythm case reports 7 11 773 - 775 2021年09月
  • Ryo Nishio; Matsumoto D; Jun-ichi Noiri; Takeshige R; Konishi H; Matsuzoe H; Ozawa M; Inoue K; Takaishi H
    Journal of cardiology cases 24 6 255 - 258 2021年05月 
    Coral reef aorta is a stenosis of the aorta due to severe calcification. We report the case of a 74-year-old woman with coral reef aorta whose hemodynamics were physiologically similar to those found in patients with renovascular hypertension. The patient had resistant hypertension, refractory edema, and renal dysfunction. Bilateral renal artery stenosis and infrarenal aortic stenosis were suspected after a Doppler ultrasound examination. Evaluation by intravascular ultrasound and pressure wire revealed that the high blood flow caused by infrarenal aortic stenosis derived from the high-flow velocity in a renal artery without stenosis. Angioplasty with balloon improved the stenosis, and the patient was relieved from a spiral of uncontrollable hypertension, edema, and renal dysfunction. This rare case was a patient with coral reef aorta who was diagnosed with uncontrollable hypertension and angioplasty was performed effectively and minimally invasively. .
  • Tanaka H; Tatsumi K; Matsuzoe H; Soga F; Matsumoto K; Hirata KI
    The international journal of cardiovascular imaging 37 4 1333 - 1341 2021年01月 
    The aim of this study was to investigate the association of type 2 diabetes mellitus (T2DM) with the development of new-onset atrial fibrillation (AF) for non-ischemic dilated cardiomyopathy (DCM) patients. We also tested the hypothesis that sodium glucose cotransporter type 2 (SGLT2) inhibitors reduce the risk of development of new-onset AF for non-ischemic DCM patients. We retrospectively studied 210 patients with non-ischemic DCM and sinus rhythm, mean age of 59.0 ± 16.7 years and left ventricular ejection fraction of 31.0 ± 8.2% (all < 45%). T2DM was identified in 60 patients (28.6%), and the remaining 150 patients (71.4%) were classified as non-T2DM patients. New-onset AF occurred in 21 patients (10.0%) over a median follow-up of 6.1 years. Kaplan-Meier curve analysis showed that non-ischemic DCM patients without T2DM experienced fewer occurrences of the development of new-onset AF compared with those with T2DM (log-rank p = 0.0003). Furthermore, global longitudinal strain in patients who showed development of new-onset AF was significantly lower than that in those whose sinus rhythm was preserved (6.4 ± 1.4% vs. 7.7 ± 2.2%, p = 0.01). Of the 60 non-ischemic DCM patients with T2DM, those treated with SGLT2 inhibitors experienced fewer occurrences of the development of new-onset AF than did those not treated with SGLT2 inhibitors (log-rank p = 0.040). T2DM is associated with the development of new-onset AF in non-ischemic DCM patients, and treatment with SGLT2 inhibitors can significantly reduce the development of new-onset AF. Our findings may thus offer a new insight into the management of non-ischemic DCM patients with T2DM.
  • Kubo I; Kazuhiro; Kajisa N; Ryu M; Akasaka H; Ogura A; Kanai M; Matsuzoe H; Matsumoto D
    Heart and vessels 36 1 76 - 84 2020年07月 
    This study aimed to clarify the effects of worsening renal function (WRF) during hospitalization on activities of daily living (ADL) at discharge of elderly heart failure (HF) patients. We included 323 consecutive patients hospitalized for HF who were prescribed phase I cardiac rehabilitation (CR) from November 2017 to April 2019. WRF was defined as a relative increase from baseline in serum creatinine of 25% or that in serum creatinine ≥ 0.3 mg/dL during hospitalization. The indices of ADL and physical function were the functional independence measure (FIM), short physical performance battery (SPPB) and 10-m comfortable gait speed as assessed at discharge. We compared background factors, clinical parameters, walking level before hospitalization, physical function, and FIM in two groups. Multiple regression analysis was performed with FIM at discharge as the dependent variable and items with P < 0.05 in bivariate correlation as independent variables. Ultimately, 160 patients were included and divided into the WRF group (n = 72) and non-WRF group (n = 88). FIM, SPPB, and 10-m comfortable walking speed were significantly lower in the WRF group. Moreover, even after adjustment for confounding factors (age, Hb, eGFR, CKD, GNRI, start day of standing), eGFR on admission (β = 0.12), WRF (β =  - 6.42) and walking level before hospitalization (β = - 10.00) were independent factors of ADL decline at discharge (adjusted R2 = 0.46). WRF during hospitalization of elderly HF patients was a factor affecting ADL decline at discharge along with walking level before hospitalization and renal function at admission.
  • Tanaka H; Tatsumi K; Matsuzoe H; Matsumoto K; Hirata KI
    Cardiovascular diabetology 19 1 84 - 84 2020年06月 

    Background

    Left ventricular (LV) longitudinal dysfunction has been identified in type 2 diabetes mellitus (T2DM) patients with preserved LV ejection fraction (LVEF). However, the impact of T2DM on LV longitudinal function or the association of LV longitudinal function with outcome for dilated cardiomyopathy (DCM) remains unclear.

    Methods

    We retrospectively studied 206 patients with non-ischemic DCM, mean age of 59 ± 17 years and LVEF of 31 ± 8% (all < 45%). All patients underwent a standard echocardiographic examination, and LV longitudinal function was assessed in terms of global longitudinal strain (GLS). Long-term outcomes were assessed, with a median follow-up period of 6.2 years, as primary endpoints of death from or hospitalization for deteriorating heart failure.

    Results

    GLS of DCM patients with T2DM (n = 55) was significantly lower than that in DCM patients without T2DM (n = 151) in spite of similar conventional LV function (7.0 ± 2.0% vs. 7.8 ± 2.2%, p = 0.03). Kaplan-Meier curves indicated that long-term outcomes for DCM patients without T2DM were better than for those with T2DM (log-rank p = 0.001). Subdividing the two groups into four with by using the median value of GLS (7.9%) showed long-term outcome was worst for DCM patients with T2DM and low GLS. Cox proportional hazards analyses demonstrated an independent association of T2DM, GLS and left atrial volume index with long-term outcome. Moreover, multiple regression analysis for the association of GLS showed that T2DM was the independent determinant parameter for GLS as well as for LVEF and left atrial volume index.

    Conclusion

    Management of DCM patients with T2DM may be improved by using GLS guidance.
  • Mukai J; Tanaka H; Sano H; Yokota S; Suto M; Takada H; Soga F; Hatani Y; Matsuzoe H; Hatazawa K; Matsumoto K; Nakayama K; Noriaki Emoto; Hirata KI
    The international journal of cardiovascular imaging 36 7 1261 - 1269 2020年03月 
    Functional tricuspid regurgitation (FTR) is associated with prognosis for various heart diseases, but its association with pulmonary hypertension (PH) remains unclear. We studied 111 PH patients. Mid-term follow-up echocardiography was performed 7.1 ± 4.1 months after PH-specific therapy. The severity of FTR was graded as none or trace, mild, moderate, or severe, while more than moderate TR was defined as significant. Moreover, mid-term improvement in FTR after therapy was defined as an improvement in severity of FTR by a grade of 1 or more. Long-term follow-up to determine the primary endpoint of death or hospitalization for heart failure lasted 39 ± 14 months. Mid-term improvement in FTR after PH-specific treatment was observed in 25 patients (23%), and the primary end points occurred in 27 patients (24%) during the long-term follow-up. The Kaplan-Meier curve indicated that the non-FTR group showed more favorable long-term outcomes than the FTR group (log-rank P = 0.008). It further indicated that patients with mid-term improvement in FTR also had more favorable long-term outcomes than those without such improvement (log-rank P = 0.03). When divided into four sub-groups based on combined assessment of baseline FTR and mid-term improvement in FTR, long-term outcomes for patients without mid-term improvement in their baseline FTR were worse than for the other sub-groups (log-rank P = 0.02). Multiple regression analysis showed that a relative change in tricuspid annular diameter at the mid-term follow-up after PH-specific therapy was the only independent determinant parameters for mid-term improvement in FTR. FTR appears to be a valuable factor for predicting long-term outcomes for PH patients, and combined assessment of baseline FTR and mid-term improvement in FTR after PH-specific therapy may have clinical implications for better management of such patients.
  • Takada H; Tanaka H; Yokota S; Mukai J; Suto M; Soga F; Hatani Y; Matsuzoe H; Hatazawa K; Matsumoto K; Fukuzawa K; Hirata KI
    Circulation journal : official journal of the Japanese Circulation Society 83 11 2312 - 2319 2019年09月 

    Background

    The underlying mechanism of mitral regurgitation (MR) in atrial fibrillation (AF) is an isolated annulus dilation caused by left atrial (LA) remodeling. However, the association of mitral valve (MV) geometry with MR in AF patients remains unclear.Methods and Results:We studied 96 AF patients with preserved left ventricular ejection fraction (LVEF). MV geometry was evaluated with 3-dimensional transesophageal echocardiography (3D-TEE). Mitral annulus area of the MR group (n=11, ≥ moderate) was significantly larger (10.6±1.8 vs. 8.2±1.5 cm2, P<0.0001), and relative posterior mitral leaflet (PML) area (PML area / mitral annulus area) was significantly smaller (0.51±0.06 vs. 0.57±0.01, P=0.002) than in the non-MR group (n=85, ConclusionsA relatively short PML plays an important role in the development of MR in AF patients. Assessment of MV geometry by 3D-TEE may thus have clinical implications for better surgical management of AF patients with significant MR.
  • Hatani Y; Tanaka H; Mochizuki Y; Suto M; Yokota S; Mukai J; Takada H; Soga F; Hatazawa K; Matsuzoe H; Matsumoto K; Hirota Y; Ogawa W; Hirata KI
    Journal of cardiology 75 2 189 - 195 2019年08月 

    Background

    Left ventricular (LV) longitudinal myocardial systolic dysfunction (LVSD) has been identified in type 2 diabetes mellitus (T2DM) patients, and it should be considered the first marker of a preclinical form of DM-related cardiac dysfunction. Overweight has been postulated to contribute to the development of LVSD in T2DM patients, but the impact of amount of body fat mass on LVSD in T2DM patients remains uncertain.

    Methods

    We studied 71 asymptomatic T2DM patients with preserved LV ejection fraction (LVEF) (all ≥55%) without coronary artery disease. LVSD for T2DM patients with preserved LVEF was identified as global longitudinal strain (GLS) <18%. Body fat mass was measured with a commercially available body composition analyzer (In Body S-10, Biospace, Tokyo, Japan), and corrected by body surface area (BFI: body fat index).

    Results

    Univariate logistic regression analysis revealed that body weight, body mass index (BMI), and BFI were all associated with LVSD, whereas multivariate logistic regression analysis showed BFI was the only variable independently associated with LVSD (OR 1.147; 95% CI 1.001-1.314; p = 0.027). For sequential logistic regression models to predict LVSD, clinical variables including age, DM duration, and HbA1c tended to be improved by addition of BMI, but without statistical significance (p = 0.09), while it was significantly improved by addition of BFI (p = 0.047).

    Conclusions

    Using BFI for the control of body compression by means of a bioelectrical impedance assay is simple and easy-to-use, and this may have clinical implications for better management of T2DM patients with preserved LVEF to prevent future development of DM-related cardiac dysfunction.
  • Soga F; Hidekazu Tanaka; Mochizuki Y; Mukai J; Suto M; Takada H; Hatani Y; Matsuzoe H; Hatazawa K; Sano H; Ooka J; Shimoura H; Kensuke Katsumoto; Fukuzawa K; Hirata KI
    Echocardiography (Mount Kisco, N.Y.) 36 5 862 - 869 2019年03月 
    OBJECTIVES:Our aim was to test the hypothesis that comprehensive simplified left atrial (LA) assessment derived from routine echocardiography may be more useful than assessment of LA volume alone for predicting atrial fibrillation (AF) recurrence after pulmonary vein isolation (PVI). METHODS:We studied 156 patients with paroxysmal AF (PAF) who had undergone PVI. Echocardiography was performed within two days before PVI. Maximum (Max-LAVi) and minimum LA volume index (Min-LAVi) were calculated with the biplane modified Simpson's method, and then normalized to the body surface area. On the basis of previous findings, the predefined cutoff value of Max-LAVi for AF recurrence was set at Max-LAVi ≥ 34 mL/m2 . ΔLA volume index (ΔLAVi) was also calculated as Max-LAVi minus Min-LAVi. The follow-up period after PVI was 24 months. RESULTS:AF recurrence was observed in 35 patients. Multivariate logistic regression analysis showed that ΔLAVi (odds ratio [OR]: 1.131; 95% confidence interval [CI]: 1.057-1.221; P < 0.001) was an independent predictor of AF recurrence. Sequential logistic regression models for predicting AF recurrence revealed that a model based on clinical variables including age, gender and AF duration (χ2  = 1.65) was improved by the addition of Max-LAVi ≥ 34 mL/m2 (χ2  = 13.8; P < 0.001), and further improved by the addition of ΔLAVi (χ2  = 18.2; P = 0.036). Of note is that only 1.02 ± 0.10 minutes per patient was needed to obtain a comprehensive LA assessment that included Max-LAVi, Min-LAVi, and ΔLAVi. CONCLUSION:This easy-to-use comprehensive simplified LA approach from routine echocardiography may well have clinical implications for better management of PAF patients.
  • Sano H; Hidekazu Tanaka; Motoji Y; Mukai J; Suto M; Takada H; Soga F; Hatani Y; Matsuzoe H; Hatazawa K; Shimoura H; Ooka J; Nakayama K; Kensuke Katsumoto; Hirotsugu Yamada; Noriaki Emoto; Hirata KI
    Echocardiography (Mount Kisco, N.Y.) 35 12 1997 - 2004 2018年10月 

    Objectives

    Pulmonary hypertension (PH) is characterized by marked and sustained elevation of pulmonary vascular resistance and pulmonary artery pressure, and subsequent right-sided heart failure. Right ventricular (RV) function and exercise capacity have been recognized as important prognostic factors for PH. Our aim was to investigate RV contractile reserve and exercise capacity during a leg-positive pressure (LPP) maneuver.

    Methods

    The study population comprised 43 PH patients and 17 normal controls. All patients underwent echocardiography at rest and during LPP stress. Exercise capacity was assessed by 6-minute walk distance for PH patients. RV relative wall thickness was calculated from dividing by RV free wall thickness by basal RV linear dimensions at end-diastole. RV function was calculated by averaging peak speckle-tracking longitudinal strain from the RV free wall. RV contractile reserve was assessed as the difference in RV free wall strain at rest and during LPP stress. Changes in left ventricular stroke volume (ΔSV) during LPP stress were also calculated.

    Results

    ΔSV and RV contractile reserve of PH patients were significantly lower than of controls (3.6 ± 6.0 mL vs 8.5 ± 2.3 mL, and 8.2 ± 11.9% vs 14.5 ± 6.6%; both P < 0.01). RV contractile reserve of PH patients with ΔSV <3.3 mL was significantly lower than of PH patients with ΔSV >3.3 mL (3.9 ± 13.2% vs 12.3 ± 8.9%; P = 0.02). ΔSV had also significant correlation with 6-minute walk distance (r = 0.42, P = 0.006). Multivariate regression analysis showed that RV relative wall thickness was an independent determinant parameter of ΔSV during LPP stress for PH patients (β = 3.2, P = 0.003).

    Conclusions

    Preload stress echocardiography in response to LPP maneuver, a noninvasive and easy-to-use procedure for routine clinical use, proved to be useful for the assessment of RV contractile reserve and exercise capacity of PH patients.
  • Hatazawa K; Tanaka H; Nonaka A; Takada H; Soga F; Hatani Y; Matsuzoe H; Shimoura H; Ooka J; Sano H; Mochizuki Y; Matsumoto K; Hirata KI
    Circulation journal : official journal of the Japanese Circulation Society 82 10 2566 - 2574 2018年07月 

    Background

    Our aim was to investigate the baseline clinical and echocardiographic parameters for predicting left ventricular (LV) dysfunction after anthracycline chemotherapy and heart failure (HF) hospitalization in a single cancer disease. Methods and Results: We studied 73 patients with malignant lymphoma and preserved LV ejection fraction (LVEF). Echocardiography was performed before and after anthracycline chemotherapy. Global longitudinal strain (GLS) was determined from 3 standard apical views. LV dysfunction after anthracycline chemotherapy was defined according to the current definition of cancer therapeutics-related cardiac dysfunction. Long-term (50-month) unfavorable outcome was prespecified as hospitalization for HF. A total of 10 patients had LV dysfunction after anthracycline chemotherapy. Multivariate logistic regression analysis showed that baseline GLS was the only independent predictor of this dysfunction. Receiver-operating characteristic curve analysis identified the optimal GLS cutoff for predicting LV dysfunction after anthracycline chemotherapy as ≤19% (P=0.008). Furthermore, the Kaplan-Meier curve indicated that fewer patients with GLS >19% were hospitalized for HF than among those with GLS ≤19% (log-rank P=0.02). For sequential logistic models, a model based on baseline clinical variables (χ2=2.9) was improved by the addition of baseline LVEF (χ2=9.0; P=0.01), and further improved by the addition of baseline GLS (χ2=13.1, P=0.04).

    Conclusions

    Watchful observation or early therapeutic intervention with established cardioprotective medications may be necessary for patients with malignant lymphoma and preserved LVEF but with abnormal GLS.
  • Matsumoto K; Onishi A; Yamada H; Kenya Kusunose; Suto M; Hatani Y; Matsuzoe H; Tatsumi K; Tanaka H; Hirata KI
    Circulation. Cardiovascular imaging 11 5 e007160  2018年05月 
    BACKGROUND:The leg-positive pressure maneuver can safely and noninvasively apply preload stress without increase in total body fluid volume. The purpose of this study was to determine whether preload stress could be useful for risk stratification of patients with heart failure with reduced ejection fraction. METHODS AND RESULTS:For this study, 120 consecutive patients with heart failure with reduced ejection fraction were prospectively recruited. The stroke work index was estimated as product of stroke volume index and mean blood pressure, and the E/e' ratio was calculated to estimate ventricular filling pressure. The echocardiographic parameters were obtained both at rest and during leg-positive pressure stress. During the median follow-up period of 20 months, 30 patients developed adverse cardiovascular events. During preload stress, stroke work index increased significantly (from 3280±1371 to 3857±1581 mm Hg·mL/m2; P<0.001) along with minimal changes in ventricular filling pressure (E/e', from 16±10 to 17±9; P<0.05) in patients without cardiovascular events. However, patients with cardiovascular events showed impairment of Frank-Starling mechanism (stroke work index, from 2863±969 to 2903±1084 mm Hg·mL/m2; P=0.70) and a serious increase in E/e' ratio (from 19±11 to 25±14; P<0.001). Both the patients without contractile reserve and those without diastolic reserve exhibited worse event-free survival than the others (P<0.001). In a Cox proportional-hazards analysis, the changes in stroke work index (hazard ratio: 0.44 per 500 mm Hg·mL/m2 increase; P=0.001) and in E/e' (hazard ratio: 2.58 per 5-U increase; P<0.001) were predictors of cardiovascular events. CONCLUSION:Contractile reserve and diastolic reserve during leg-positive pressure stress are important determinants of cardiovascular outcomes for patients with heart failure with reduced ejection fraction.
  • Matsuzoe H; Tanaka H; Hatazawa K; Hatani Y; Matsumoto K; Shinke T; Hirata KI
    Journal of echocardiography 16 3 150 - 151 2018年01月
  • Hatani Y; Hidekazu Tanaka; Mochizuki Y; Hatazawa K; Matsuzoe H; Shimoura H; Ooka J; Sano H; Sawa T; Motoji Y; Ryo-Koriyama K; Kensuke Katsumoto; Otake H; Shinke T; Hirata KI
    Echocardiography (Mount Kisco, N.Y.) 35 2 218 - 226 2017年11月 
    OBJECTIVES:The closure of atrial septal defect (ASD) results in normalized left ventricular (LV) and right ventricular (RV) geometry, and can increase LV stroke volume (LVSV), but the parameters associated with this increase after the closure of ASD remain uncertain. METHODS:Seventy ASD patients, who underwent transcatheter closure, were studied. Their mean age was 57.80 ± 16.88 years, 42 (60%) were female, and LV ejection fraction (LVEF) was 66.76% ± 7.91% (all ≥55%). Transthoracic echocardiography was performed before and 3 months after the procedure. Global longitudinal strain (GLS) was determined as the average peak speckle tracking strain of 18 segments from the 3 standard apical views, LV dispersion was defined as standard deviation of time-to-peak strain from the same views, and RV systolic function was calculated by averaging the 3-regional peak speckle tracking longitudinal strains from the RV free wall. A significant relative increase in LVSV between before and 3 months after the closure was defined as ∆LVSV ≥15%. Twenty age-, gender-, and LVEF-matched controls served as the control group. RESULTS:Global longitudinal strain (GLS) and RV free wall strain were similar for ASD patients and controls, but LV dispersion in ASD patients was significantly larger. Global longitudinal strain (GLS) remained unchanged after transcatheter closure, whereas RV free wall strain and LV dispersion decreased significantly. An important finding of the multivariate logistic regression analysis showed that ∆LV dispersion was the only independent determinant of increased LVSV after the closure (OR 1.023; 95% CI 1.001-1.046; P < .01). CONCLUSIONS:The assessment of LV dispersion may well have clinical implications for better management of ASD patients after transcatheter closure.
  • Suto M; Tanaka H; Mochizuki Y; Mukai J; Takada H; Soga F; Dokuni K; Hatani Y; Hatazawa K; Matsuzoe H; Sano H; Shimoura H; Ooka J; Matsumoto K; Hirota Y; Ogawa W; Hirata KI
    Cardiovascular diabetology 16 1 145 - 145 2017年11月 
    BACKGROUND:Coexistence of left ventricular (LV) longitudinal myocardial systolic dysfunction with LV diastolic dysfunction could lead to heart failure with preserved ejection fraction (HFpEF). Diabetes mellitus (DM) is known as a significant factor associated with HFpEF. Although the mechanisms of DM-related LV myocardial injury are complex, it has been postulated that overweight contributes to the development of LV myocardial injury in type 2 diabetes mellitus (T2DM) patients. However, the precise impact of overweight on LV longitudinal myocardial systolic function in T2DM patients remains unclear. METHODS:We studied 145 asymptomatic T2DM patients with preserved LV ejection fraction (LVEF) without coronary artery disease. LV longitudinal myocardial systolic function was assessed by global longitudinal strain (GLS), which was defined as the average peak strain of 18-segments obtained from standard apical views. Overweight was defined as body mass index (BMI) ≥ 25 kg/m2. Ninety age-, gender- and LVEF-matched healthy volunteers served as controls. RESULTS:GLS of overweight T2DM patients was significantly lower than that of non-overweight patients (17.9 ± 2.4% vs. 18.9 ± 2.6%, p < 0.05), whereas GLS of both overweight and non-overweight controls was similar (19.8 ± 1.3% vs. 20.4 ± 2.1%, p = 0.38). Furthermore, multiple regression analysis revealed that for T2DM patients, BMI was the independent determinant parameters for GLS as well as LV mass index. CONCLUSIONS:Overweight has a greater effect on LV longitudinal myocardial systolic function in T2DM patients than on that in non-DM healthy subjects. Our finding further suggests that the strict control of overweight in T2DM patients may be associated with prevention of the development of HFpEF.
  • Matsuzoe H; Kensuke Katsumoto; Shumpei; Toba T; Kawamori H; Shimoyama S; Hidekazu Tanaka; Shinke T; Hirata KI
    Echocardiography (Mount Kisco, N.Y.) 34 11 1717 - 1720 2017年10月 
    This report concerns an 83-year-old woman with aortic stenosis (AS) who had a history of repetitive hospitalization due to decompensated heart failure. Although her clinical history was compatible with significant AS, findings for aortic valve area, hemodynamics, and valvular calcium burden were discrepant. Multiplanar reconstruction images revealed the membranous structures attached to a subcommissural lesion, which resulted in severe stenosis. The patient had a favorable clinical course after transcatheter aortic valve replacement. This is the first reported case of severe AS due to the subcommissural adhesions, which were successfully visualized by means of echocardiography and computed tomography.
  • Ooka J; Tanaka H; Hatani Y; Hatazawa K; Matsuzoe H; Shimoura H; Sano H; Sawa T; Motoji Y; Mochizuki Y; Ryo-Koriyama K; Matsumoto K; Fukuzawa K; Hirata KI
    International heart journal 58 5 724 - 730 2017年09月 
    Although right ventricular (RV) pacing is the only effective treatment for patients with symptomatic bradycardia, it creates left ventricular (LV) dyssynchrony, which can induce LV dysfunction and heart failure. The current criterion for consideration of cardiac resynchronization therapy (CRT) is LV ejection fraction (LVEF) ≤ 35%, but indication for CRT in patients required for RV pacing with LVEF > 35% remains unclear.We studied 40 patients, all LVEF ≥ 35%, who had undergone implantable cardioverter-defibrillator implantation with RV pacing < 5%. Echocardiography was performed at baseline and during RV pacing. LV dyssynchrony was defined as anteroseptal-to-posterior wall delay from the mid-LV short-axis view using two-dimensional speckle-tracking radial strain (significant: ≥ 130 ms). Patients were divided into two groups based on baseline LVEF: normal LVEF ( ≥ 50%; n = 20) and mildly reduced LVEF (35-50%; n = 20).LVEF and LV dyssynchrony in patients with mildly reduced LVEF deteriorated significantly during RV pacing compared to those in patients with normal LVEF. Moreover, changes in LV dyssynchrony during RV pacing significantly correlated with changes in LVEF (r = -0.44, P < 0.01). Multivariate logistic regression analysis showed that baseline LVEF was the only independent predictor and baseline LVEF < 48% predictive of significant LV dyssynchrony during RV pacing.The extent of RV pacing-induced LV dysfunction may be associated with baseline LV function. These adverse effects on patients with mildly reduced LVEF of 35-50% and indications for RV pacing due to bradycardia can thus be prevented by CRT.
  • Izawa Y; Shumpei; Tatsuya Nishii; Matsuzoe H; Imada H; Suehiro H; Nakayama K; Matsumoto K; Tanaka H; Fujiwara S; Fukuzawa K; Hirata KI
    Echocardiography (Mount Kisco, N.Y.) 34 7 1073 - 1076 2017年07月 
    Preprocedural recognition of the segment of latest mechanical contraction along with the anatomy of the coronary venous system is important for successful and effective cardiac resynchronization therapy. We present a case of ischemic cardiomyopathy who underwent implantation of a cardiac resynchronization therapy device with a defibrillator, which was facilitated by preprocedural computed tomographic images reconstructed to visualize the left ventricular slab and the coronary venous system simultaneously on the cardiac contour. The present reconstruction method using computed tomography is optimal and feasible method to incorporate the echocardiographic findings into the procedure performed under fluoroscopy appropriately.
  • Matsuzoe H; Matsumoto K; Tanaka H; Hatani Y; Hatazawa K; Shimoura H; Ooka J; Sano H; Ryo-Koriyama K; Shinke T; Yamada H; Okita Y; Hirata KI
    Circulation journal : official journal of the Japanese Circulation Society 81 12 1927 - 1935 2017年06月 

    Background

    Although aortic valve intervention is recommended for virtually all symptomatic patients with aortic stenosis (AS), how urgently the intervention should be performed remains controversial. The aim of this study was thus to determine whether the preload reserve in response to leg-positive pressure (LPP) maneuver could serve for decision-making for AS patients awaiting aortic valve intervention.Methods and Results:Sixty-eight patients with symptomatic AS, who were referred for aortic valve intervention, were recruited. Stroke volume (SV) was assessed by means of pulsed-wave Doppler, and the ratio between transmitral E wave and mitral annular velocity (e') was calculated to estimate ventricular filling pressure. While waiting for intervention, 11 patients experienced preoperative cardiac events. During acute preload stress, forward SV for patients without cardiac events increased significantly (from 43±9 to 49±10 mL/m2, P<0.01) along with a minimal change in filling pressure (E/e': from 20±8 to 21±9, NS). For patients with cardiac events, the Frank-Starling mechanism was significantly impaired (SVi: from 40±9 to 38±7 mL/m2, NS), while filling pressure increased to the critical level (E/e': from 24±8 to 31±8, P<0.001). Both the patients without flow reserve (∆SVi <4.5 mL/m2) and those without diastolic reserve (∆E/e' ≥2.9) exhibited significantly worse event-free survival than the others (P<0.05, respectively).

    Conclusions

    Assessment of preload reserve during LPP stress could facilitate risk stratification of patients with severe AS waiting for aortic valve intervention.
  • Sano H; Tanaka H; Motoji Y; Fukuda Y; Mochizuki Y; Hatani Y; Matsuzoe H; Hatazawa K; Shimoura H; Ooka J; Ryo-Koriyama K; Nakayama K; Matsumoto K; Noriaki Emoto; Hirata KI
    The international journal of cardiovascular imaging 33 3 313 - 321 2016年10月 
    Mid-term right ventricular (RV) reverse remodeling after treatment in patients with pulmonary hypertension (PH) is associated with long-term outcome as well as baseline RV remodeling. However, baseline factors influencing mid-term RV reverse remodeling after treatment and its prognostic capability remain unclear. We studied 54 PH patients. Mid-term RV remodeling was assessed in terms of the RV area, which was traced planimetrically at the end-systole (RVESA). RV reverse remodeling was defined as a relative decrease in the RVESA of at least 15% at 10.2 ± 9.4 months after treatment. Long-term follow-up was 5 years. Adverse events occurred in ten patients (19%) and mid-term RV reverse remodeling after treatment was observed in 37 (69%). Patients with mid-term RV reverse remodeling had more favorable long-term outcomes than those without (log-rank: p = 0.01). Multivariate logistic regression analysis showed that RV relative wall thickness (RV-RWT), as calculated as RV free-wall thickness/RV basal linear dimension at end-diastole, was an independent predictor of mid-term RV reverse remodeling (OR 1.334; 95% CI, 1.039-1.713; p = 0.03). Moreover, patients with RV-RWT ≥0.21 showed better long-term outcomes than did those without (log-rank p = 0.03), while those with RV-RWT ≥0.21 and mid-term RV reverse remodeling had the best long-term outcomes. Patients with RV-RWT <0.21 and without mid-term RV reverse remodeling, on the other hand, had worse long-term outcomes than other sub-groups. In conclusions, RV-RWT could predict mid-term RV reverse remodeling after treatment in PH patients, and was associated with long-term outcomes. Our finding may have clinical implications for better management of PH patients.
  • Shimoura H; Tanaka H; Matsumoto K; Mochizuki Y; Hatani Y; Hatazawa K; Matsuzoe H; Ooka J; Sano H; Sawa T; Motoji Y; Ryo-Koriyama K; Hirata KI
    Heart and vessels 32 5 584 - 590 2016年10月 
    Left ventricular (LV) hypertrophy (LVH) is an independent cardiovascular risk factor for heart failure (HF) patients. The renin-angiotensin system plays a key role in LVH, and since olmesartan increases plasma angiotensin-(1-7) through an increase in angiotensin-converting enzyme-related carboxypeptidase (ACE2) expression, it was hypothesized to reduce LVH, unlike other angiotensin II receptor blockers (ARBs). The objective of this study was therefore to investigate the effects of a changeover from other ARBs to olmesartan on LVH in HF patients. Participants enrolled in this prospective trial were 64 outpatients with stable HF who had received ARBs other than olmesartan for more than 1 year (age: 59 ± 13 years). Transthoracic echocardiography and laboratory tests were performed before and 6 months after administration of olmesartan. Other drugs were not changed during follow-up. The primary end point was defined as a change in LV mass index (LVMI) from baseline up to 6 months after administration of olmesartan. No significant changes were observed in blood pressures and heart rate after administration of olmesartan. LVMI showed a significant decrease from 119 ± 38 to 110 ± 24 g/m2 (p = 0.007) 6 months after administration of olmesartan, and further decreased from 110 ± 24 to 103 ± 35 g/m2 (p = 0.0003) after 12 months. Moreover, this reduction tended to be more prominent in patients with LVH. In conclusions, LVH in HF patients was reduced by the changeover to olmesartan. This finding may well have clinical implications for better management of HF patients.
  • Matsuzoe H; Tanaka H; Matsumoto K; Toki H; Shimoura H; Ooka J; Sano H; Sawa T; Motoji Y; Mochizuki Y; Ryo K; Fukuzawa K; Yoshida A; Hirata K
    European heart journal. Cardiovascular Imaging 17 3 334 - 42 2015年07月 

    Aims

    Current guidelines recommend implantation of prophylactic implantable cardioverter-defibrillators (ICD) in patients with left ventricular (LV) ejection fraction (EF) <35%. We explored the prognostic factors of fatal ventricular arrhythmias for heart failure (HF) patients with LVEF ≥35%.

    Methods and results

    We retrospectively studied 72 patients with LVEF of 52 ± 12% (all ≥35%) who had undergone ICD implantation. Heterogeneity of LV regional myocardial contraction was defined as standard deviation of peak strain (dyssynergy index) and time-to-peak strain (dispersion index) from 18 LV segments determined by speckle tracking. Fatal ventricular arrhythmias with appropriate ICD therapy occurred in 34 patients (47%) during a median follow-up of 17 months. Receiver operating characteristic curve analysis identified dispersion index ≥101 ms and dyssynergy index ≥6.1% as predictors of fatal ventricular arrhythmias (P = 0.004 and P = 0.0001, respectively). In addition, the combination of dispersion index ≥101 ms and dyssynergy index ≥6.1% was the most predictive of fatal ventricular arrhythmias with a sensitivity of 77%, specificity of 79%, and area under the curve of 0.795 (P < 0.0001). A sequential Cox model based on clinical and conventional echocardiographic variables including age, gender, HF aetiology, and LVEF (χ(2) = 4.8) was improved, but not statistically significant (χ(2) = 4.9; P = 0.82), by addition of global longitudinal strain, whereas improvement by the addition of the dispersion index (χ(2) = 8.9; P = 0.04) and further improvement by the addition of the dyssynergy index (χ(2) = 20.2; P < 0.005).

    Conclusion

    Combined assessment of LV dyssynergy and dispersion can enhance predictive capability for fatal ventricular arrhythmias in patients with LVEF ≥35% and may have potential for better management of such patients.
  • 松添 弘樹; 清水 宏紀; 畑澤 圭子; 中村 浩彰; 熊谷 寛之; 辻 隆之; 井上 通彦; 則定 加津子; 高見 薫; 七星 雅一; 角谷 誠; 大西 祥男
    心臓 46 1 54 - 60 公益財団法人 日本心臓財団 2014年 
    症例1 : 30歳代, 女性. アルコール依存症, 神経性食思不振症にて精神科外来加療中であったが1 年前より通院を中断していた. 2012年5 月下旬の夕食後, 突然の痙攣様発作で救急要請. 救急隊到着時, 心室細動波形で心肺蘇生を開始, 合計3 回の電気的除細動が施行され当院搬入となった. び漫性左室壁運動低下を認め, 血清カリウム2.2mEq/L, 血清リン1.1mg/dLと電解質異常を認めていた. 入院後電解質補正を行い不整脈は消失したが, 低酸素脳症のため意識レベルの改善なく経過した. 症例2 : 40歳代, 男性. 2012年5 月下旬より下肢筋力低下, 起立困難から脳梗塞を疑われ近医で頭部精査入院となったが, 明らかな脳神経疾患は認めなかった. 前医第2 病日の朝食後, 突然心室細動が出現し心肺蘇生が施行されるも, 難治性心室頻拍となり某院救急センターへ搬送. 冠動脈造影にて有意狭窄はなかったが, 薬剤的, 電気的にもコントロール困難で経皮的心肺補助装置 (percutaneous cardiopulmonary support ; PCPS) 挿入下に当院に紹介搬送となった. 当院では多形性心室頻拍 (torsades de pointes ; TdP) を認め, び漫性に左室壁運動が低下しており, 血清カリウム : 1.6mEq/L, 血清リン : 1.6mg/dLと電解質異常を認めた. 入院後電解質補正によりTdPは消失, PCPS抜去にいたるも低酸素脳症から意識障害が遷延し第10病日に死亡退院となった. 両症例ともアルコール依存症を背景に持ち, カロリー摂取後の致死的不整脈出現からrefeeding症候群の関与が疑われた. 慢性低栄養患者に発症した若年性心肺停止患者ではrefeeding症候群の可能性を常に考慮する必要があると考えられた.
  • 中村 浩彰; 角谷 誠; 畑澤 圭子; 松添 弘樹; 辻 隆之; 井上 通彦; 熊谷 寛之; 則定 加津子; 高見 薫; 伴 親徳; 開發 謙次; 七星 雅一; 清水 宏紀; 大西 祥男
    心臓 45 7 834 - 834 公益財団法人 日本心臓財団 2013年
  • 松添 弘樹; 中村 宏彰; 岡田 武哲; 姜 臣鎬; 石田 明彦; 足立 靖
    心臓 45 7 908 - 910 公益財団法人 日本心臓財団 2013年
  • 松添 弘樹; 姜 臣鎬; 平 和樹; 石田 明彦
    心臓 44 11 1406 - 1411 公益財団法人 日本心臓財団 2012年 
    症例は,37歳,女性.3回経妊3回経産,某院産婦人科にて妊娠管理中36週より血圧上昇と尿蛋白を認め,重症妊娠高血圧症候群と診断された.38週4日に分娩誘発中,胎児心拍低下し緊急帝王切開で女児出産,産褥後,高血圧は改善した.産褥18日目より夜間呼吸困難が出現,産褥36日目に増悪を認め救急搬送され,胸部X線写真で肺うっ血と心胸郭比拡大と,心エコー図上,左室駆出率24%と高度低下を認め,心不全の診断で入院となった.入院後,通常の心不全治療とともに抗プロラクチン療法併用により心不全は改善し,左室壁運動の改善が得られた.妊娠関連の心筋症は本邦においてはいまだ実態が把握されておらず,確立された治療法がない.従来の心不全加療に加え,抗プロラクチン療法の有効性が少数例ながら報告されており,今後症例数を増やした検討が待たれる.

書籍

講演・口頭発表等

  • The Efficacy of Introducing IABP in Patients with ST-elevation Myocardial Infrction of the Right Coronary Artery Due to Thrombus  [通常講演]
    Nao Oda; Hiroki Matsuzoe; Ryo Nishio; Wako Suehiro; Ken Kinugwa; Ryo Takeshige; Atsushi Suzuki; Daisuke Matsumoto; Kunihiko Kiuchi; Hiroshi Takaishi
    第88回日本循環器学会学術集会 2024年03月 ポスター発表
  • 一過性乳頭筋機能不全から急性僧帽弁閉鎖不全症を来した急性冠症候群の一例  [通常講演]
    小田 奈央; 松添 弘樹; 衣川 謙; 末廣 和子; 竹重 遼; 鈴木 敦; 西尾 亮; 松本 大典; 木内 邦彦; 高石 博史
    第136回日本循環器学会近畿地方会 2023年12月 口頭発表(一般)
  • 拡張型心筋症に合併した巨大左室内血栓に対して外科的血栓除去を要した一例  [通常講演]
    衣川 謙; 松添 弘樹; 西尾 亮; 松本 大典; 高石 博史; 藤本 将人; 佐藤 俊輔; 莇 隆; 菅野 天裕; 稲葉 真由美
    第241回 日本内科学会近畿地方会 2023年09月 口頭発表(一般)
  • 心耳腫瘍を疑う形態変化を引き起こし、診断に困難を伴った収縮性心膜炎の1例  [通常講演]
    小田奈央; 松添弘樹; 佃 美奈; 衣川謙; 末廣和子; 竹重遼; 小西弘樹; 西尾亮; 小澤牧人; 松本大典; 佐藤俊輔; 井上享三; 莇隆; 高石博史
    第135回 日本循環器学会近畿地方会 2023年07月 口頭発表(一般)
  • 視野障害で来院し左房粘液腫と鑑別を要した左房原発心臓内膜肉腫の若年女性の一例  [通常講演]
    佃美奈; 松添弘樹; 佐藤俊輔; 菅野天裕; 稲葉真由美; 藤本将人; 井上享三; 高石博史; 莇隆
    第34回 日本心エコー図学会学術集会 2023年04月 口頭発表(一般)
  • A Case Report of Fulminant Eosinophilic Myocarditis in Eosinophilic Granulomatosis with Polyangiitis Followed by Cardiac Multimodality Imaging and Systemic Evaluation  [通常講演]
    Jun-ichi Noiri; Hiroki Matsuzoe; Mina Tsukuda; Sato Namura; Nao Oda; Ken Kinugawa; Wako Suehiro; Ryo Takeshige; Hiroki Konishi; Akinori Matsumoto; Ryo Nishio; Makito Ozawa; Daisuke Matsumoto; Hiroshi Takaishi
    第87回 日本循環器学会学術集会 2023年03月 口頭発表(一般)
  • 重症心不全入院時にイバブラジンの内服で、心不全コントロールが良好となった高度収縮不全心の3例  [通常講演]
    末廣和子; 松添弘樹; 小西弘樹; 西尾亮; 小澤牧人; 松本大典; 高石博史
    第70回 日本心臓病学会学術集会 2022年09月 口頭発表(一般)
  • 強心薬持続投与からの離脱にイバブラジン内服が奏功した高度収縮不全心の一例  [通常講演]
    高橋七海; 松添弘樹; 衣川謙; 末廣和子; 野杁純一; 竹重遼; 小西弘樹; 松本晃典; 西尾亮; 小澤牧人; 松本大典; 高石博史
    第133回 日本循環器学会近畿地方会 2022年06月 口頭発表(一般)
  • “Pseudo Dilated Cardiomyopathy” An autopsy case of nonbacterial thrombotic endocarditis with dilated cardiomyopathy-like changes  [通常講演]
    Sato Namura; Hiroki Matsuzoe; Ken Kinugawa; Wako Suehiro; Junichi Noiri; Ryo Takeshige; Hiroki Konishi; Akinori Matsumoto; Ryo Nishio; Makito Ozawa; Daisuke Matsumoto; Mayumi Inaba; Hiroshi Takaishi
    第86回 日本循環器学会学術集会 2022年03月 口頭発表(一般)
  • A Case of Venous Thromboembolism Caused by Protein C Deficiency due to a Novel Genetic Mutation)  [通常講演]
    Junichi Noiri; Hiroki Matsuzoe; Ryo Takeshige; Hiroki Konishi; Akinori Matsumoto; Ryo Nishio; Makito Ozawa; Daisuke Matsumoto; Hiroshi Takaishi
    第86回 日本循環器学会学術集会 2022年03月 口頭発表(一般)
  • 【臨床症例画像報告集(画論29th The Best Imageより)】感染性心内膜炎精査で肺動脈弁下型心室中隔欠損症の初回同定と、さらに2つの瘻孔部位も同定した一例
    松添 弘樹
    日本放射線技術学会雑誌 78(4付録) 47-47 2022年4月 2021年12月
  • 心室中隔欠損症を原因とした感染性心内膜炎により、心内に複数個所の穿孔を生じた高齢男性の一例  [通常講演]
    下山由希子; 松添弘樹; 佐藤俊輔; 衣川謙; 末廣和子; 野杁純一; 竹重遼; 小西弘樹; 松本晃典; 西尾亮; 小澤牧人; 松本大典; 莇隆; 高石博史
    第132回 日本循環器学会近畿地方会 2021年12月 口頭発表(一般)
  • 抗凝固療法抵抗性深部静脈血栓症に対して血栓溶解療法と静脈ステント留置術の併用が奏功した一例  [通常講演]
    新美 舞; 松添 弘樹; 野杁 純一; 西尾 亮; 高石 博史
    第234回 日本内科学会近畿地方会 2021年12月 口頭発表(一般)
  • Valsalva洞穿孔の成因としてAerococcus urinae (A.urinae) による感染性心内膜炎が疑われた一剖検例
    中辻孝太; 松添弘樹; 西尾亮; 小澤牧人; 松本大典; 高石博史
    第69回 日本心臓病学会学術集会 2021年09月 口頭発表(一般)
  • 僧帽弁置換術後2か月後の急性心不全でstuck valveが判明した維持透析患者の一例
    末廣和子; 松添弘樹; 佐藤俊輔; 河本達也; 中西麻衣; 寺村一裕; 高石博史; 莇隆
    第94回 日本超音波医学会学術集会 2021年05月 口頭発表(一般)
  • A case of acute myocardial infarction caused by isolated occlusion of a septal branch diagnosed by a cardiac MRI  [通常講演]
    Ken Kinugawa; Hiroki Matsuzoe; Yoshinori Nagasawa; Hiroki Konishi; Ryo Nishio; Makito Ozawa; Yasushi Tanaka; Daisuke Matsumoto; Hiroshi Takaishi
    第29回 日本心血管インターベンション治療学会 2021年02月 口頭発表(一般)
  • 心肺運動負荷試験が運動耐容能低下の鑑別に寄与した抗ミトコンドリアM2抗体陽性心不全の一例
    名村 咲音; 松添 弘樹; 庄田 武司; 上田 直子; 高石 博史
    第230回 日本内科学会 近畿地方会 2020年12月 口頭発表(一般)
  • 右室内感染性心内膜炎の一因として外傷性三尖弁閉鎖不全症が疑われた中年男性の1例
    酒井 鷹平; 松添 弘樹; 長澤 圭典; 西尾 亮; 小澤 牧人; 田中 康史; 松本 大典; 佐藤 俊輔; 高石 博史
    第225回 日本内科学会 近畿地方会 2019年09月 口頭発表(一般)
  • Integrated assessment of aortic valve resistance using multi-detector computed tomography and echocardiography reflects aortic valvular burden and has prognostic value in patients with aortic stenosis  [通常講演]
    H. Matsuzoe; K. Matsumoto; H. Tanaka; N. Tahara; Y. Izawa; T. Toba; S. Mori; M. Suto; J. Mukai; H. Takada; F. Soga; Y. Hatani; K. Hatazawa; S. Shimoyama; K. Hirata
    EUROPEAN HEART JOURNAL 39 1376-1376 2018年08月 ポスター発表
  • 重症度の判定に苦慮した大動脈弁狭窄症の一例
    松添 弘樹; 松本 賢亮; 森 俊平; 鳥羽 敬義; 川森 裕之; 下山 真介; 田中 秀和; 新家 俊郎; 平田健一
    第124回 日本循環器学会 近畿地方会 2017年11月 口頭発表(一般)
  • 外科的心房中隔欠損修復後44年後に経皮的心房中隔欠損閉鎖術を施行した高齢女性の一例
    松添弘樹; 田中秀和; 須藤麻貴子; 向井淳; 高田裕基; 曽我文隆; 羽渓優; 畑澤圭子; 松本賢亮; 平田健一
    第44回 日本超音波医学会 近畿地方会 2017年09月 口頭発表(一般)
  • 高度大動脈弁狭窄症患者における前負荷予備能の検討  [通常講演]
    松添 弘樹; 松本 賢亮; 田中 秀和; 曽我 文隆; 高田 裕基; 羽渓 優; 畑澤 圭子; 下浦 広之; 大岡 順一; 佐野 浩之; 望月泰秀; 郡山 恵子; 平田 健一
    第122回日本循環器学会近畿地方会 2016年11月 口頭発表(一般)
  • Significant prognostic value of acute preload stress echocardiography by using leg-positive pressure maneuver in patients with severe aortic stenosis
    Hiroki Matsuzoe; Kensuke Matsumoto; Hidekazu Tanaka; Hiroki Takada; Fumitaka Soga; Yutaka Hatani; Keiko Hatazawa; Hiroyuki Shimoura; Junichi Ooka; Hiroyuki Sano; Keiko Ryo-Koriyama; Ken-ichi. Hirata
    CIRCULATION 134 PJ-180 2016年11月 2016年11月 ポスター発表
  • 症候性大動脈弁狭窄症患者における前負荷予備能の検討
    松添弘樹; 松本賢亮; 田中秀和; 高田裕基; 曽我文隆; 羽渓優; 畑澤圭子; 大岡順一; 下浦広之; 佐野浩之; 佐和琢磨; 望月泰秀; 郡山恵子; 平田健一
    第64回日本心臓病学会学術集会 2016年09月 口頭発表(一般)
  • Left ventricular dyssynergy and dispersion as determinant factors of fatal ventricular arrhythmias in patients with mildly reduced ejection fraction
    Hiroki Matsuzoe; Hidekazu Tanaka; Kensuke Matsumoto; Kumiko Dokuni; Yutaka Hatani; Keiko Hatazawa; Hiromi Toki; Hiroyuki Shimoura; Junichi Ooka; Hiroyuki Sano; Takuma Sawa; Yoshiki Motoji; Yasuhide Mochizuki; Keiko Ryo; Koji Fukuzawa; Ken-ichi Hirata
    CIRCULATION 132 2015年11月 ポスター発表
  • Left Ventricular Dyssynergy and Dispersion as Determinant Factors of Fatal Ventricular Arrhythmias in Patients with Mild Reduced Ejection Fraction  [通常講演]
    Hiroki Matsuzoe; Hidekazu Tanaka; Kensuke Matsumoto; Kumiko Dokuni; Yutaka Hatani; Keiko Hatazawa; Hiromi Toki; Hiroyuki Shimoura; Junichi Ooka; Hiroyuki Sano; Takuma Sawa; Yoshiki Motoji; Yasuhide Mochizuki; Keiko Ryo; Koji Fukuzawa; Akihiro Yoshida; Ken-ichi Hirata
    第 79 回日本循環器学会学術集会 2015年04月 ポスター発表
  • 大動脈解離に合併した感染性動脈内膜炎の1例  [通常講演]
    田中沙苗; 田中秀和; 望月泰秀; 堂國久美子; 羽渓優; 畑澤圭子; 松添弘樹; 下浦広之; 佐野浩之; 大岡順一; 土岐啓己; 佐和琢磨; 元地由樹; 松本賢亮; 松森正術; 大北裕; 平田健一
    第118回 日本循環器学会近畿地方会 2014年11月 口頭発表(一般)
  • Serum and Thrombus Fatty Acid Composition at the Onset of Acute CoronarySyndrome  [通常講演]
    YASUDA Tomoyuki; IRINO Yasuhiro; SHIMIZU Hiroki; MORI Kenta; MORI Takeshige; HATAZAWA Keiko; MATSUZOE Hiroki; TSUJI Takayuki; INOUE Michihiko; KUMAGAI Hiroyuki; TAKAMI Kaoru; NORISADA Kazuko; NAKAMURA Hiroaki; NANAHOSHI Masakazu; KADOTANI Makoto; TOH Ryuji; ISHIDA Tatsuro; HIRATA Ken-ichi; HIRATA Ken-ichi
    第78回日本循環器学会学術集会 2014年03月 口頭発表(一般)
  • Evaluation of the Risk Predictors for In-Hospital Mortality of ST-segment Elevation Myocardial Infarction (STEMI) Associated with Left Main Coronary Artery  [通常講演]
    Matsuzoe H; Kadotani M; Nakamura H; Hatazawa K; Tsuji T; Inoue M; Kumagai H; Norisada K; Takami K; Yasuda T; Nanahoshi M; Shimizu H; Ohnishi Y
    第 78 回日本循環器学会学術集会 2014年03月 口頭発表(一般)
  • 低K 血症および低Mg 血症を契機に多形性心室頻拍を認めた先天性QT 延長症候群の一例  [通常講演]
    矢冨 敦亮; 熊谷 寛之; 清水 宏紀; 高見 薫; 畑澤 圭子; 松添 弘樹; 辻 隆之; 井上 通彦; 則定 加津子; 中村 浩彰; 伴 親徳; 安田 知行; 七星 雅一; 角谷 誠; 大西 祥男
    第116回 日本循環器学会近畿地方会 2013年11月 口頭発表(一般)
  • 難治性心不全患者におけるトルバプタンの使用経験
    三和 圭介; 井上 通彦; 清水 宏紀; 角谷 誠; 七星 雅一; 安田 知行; 中村 浩彰; 則定加 津子; 高見 薫; 熊谷 寛之; 辻 隆之; 松添 弘樹; 畑澤 圭子; 矢富 敦亮; 大西 祥男
    第116回 日本循環器学会近畿地方会 2013年11月 口頭発表(一般)
  • 回旋枝の慢性完全閉塞を有する左前下行枝の急性閉塞に対して前下行枝1枝のみにPCI を行い救命し得た1例  [通常講演]
    矢富 敦亮; 井上 通彦; 清水 宏紀; 角谷 誠; 七星 雅一; 安田 知行; 中村 浩彰; 則定 加津子; 高見 薫; 熊谷 寛之; 辻 隆之; 松添 弘樹; 畑澤 圭子; 三和 圭介; 大西祥男
    第116回 日本循環器学会近畿地方会 2013年11月 口頭発表(一般)
  • 下肢静脈瘤に対する血管内レーザー焼灼術(Endovenous laser ablation: EVLA)の初期成績  [通常講演]
    中村 浩彰; 角谷 誠; 畑澤 圭子; 松添 弘樹; 辻 隆之; 井上通彦; 熊谷 寛之; 高見 薫; 則定 加津子; 安田 知行; 七星雅一; 清水 宏紀; 大西 祥男; 前田 翔; 岩谷 博篤
    第116回 日本循環器学会近畿地方会 2013年11月 口頭発表(一般)
  • 心原性ショックに合併した心房頻拍の治療にドブタミンとランジオロール併用が有効であった一例
    安田 知行; 清水 宏紀; 畑澤 圭子; 松添 弘樹; 辻 隆之; 井上 通彦; 熊谷 寛之; 高見 薫; 則定 加津子; 中村 浩彰; 伴 親徳; 七星 雅一; 角谷 誠; 大西 祥男
    第116回 日本循環器学会近畿地方会 2013年11月 口頭発表(一般)
  • 経時的にJ 波およびQ 波の変化を認め,心室細動を発症した一例
    畑澤 圭子; 清水 宏紀; 松添 弘樹; 辻 隆之; 井上 通彦; 熊谷 寛之; 高見 薫; 則定 加津子; 中村 浩彰; 伴 親徳; 七星 雅一; 角谷 誠; 大西 祥男
    第116回 日本循環器学会近畿地方会 2013年11月
  • 後天性von Willebrand 病を合併し,心不全を繰り返した重症大動脈弁狭窄症の1症例
    辻 隆之; 清水 宏紀; 畑澤 圭子; 松添 弘樹; 井上 通彦; 熊谷 寛之; 高見 薫; 則定 加津子; 中村 浩彰; 安田 知行; 七星 雅一; 角谷 誠; 大西 祥男
    第116回 日本循環器学会近畿地方会 2013年11月 口頭発表(一般)
  • 当院における左主幹部を責任病変とした ACS 症例の検討  [通常講演]
    松添 弘樹; 角谷 誠; 中村 浩彰; 畑澤 圭子; 井上 通彦; 辻 隆之; 熊谷 寛之; 則定 加津子; 高見 薫; 安田 知行; 七星 雅一; 清水 宏紀; 大西 祥男
    第116回 日本循環器学会 近畿地方会 2013年11月 口頭発表(一般)
  • 急性心不全を契機に診断された HDR 症候群の一例  [通常講演]
    松添 弘樹; 井上 通彦; 辻 隆之; 中村 浩彰; 清水 宏紀; 大西 祥男; 難波 多挙; 臼井 健
    第 201回 日本内科学会 近畿地方会 2013年09月 口頭発表(一般)
  • 高度石灰化大動脈狭窄病変に対して、血管内治療が有効であった1例
    中村 浩彰; 角谷 誠; 畑澤 圭子; 松添 弘樹; 辻 隆之; 井上 通彦; 則定 加津子; 高見 薫; 伴 親徳; 七星 雅一; 開發 謙次; 清水 宏紀; 大西 祥男
    第22回日本心血管インターベンション治療学会総会 2013年07月 口頭発表(一般)
  • LMT 病変に留置した biolimus eluting stent(NOBORI) の急性期の recoil が原因と考えられた ステント血栓症 ( の一例  [通常講演]
    松添 弘樹; 角谷; 誠; 伴; 親徳; 七星 雅一
    第22回日本心血管インターベンション治療学会総会 2013年07月 口頭発表(一般)
  • 心肺停止の原因としてRefeeding症候群が考えられた2症例
    松添 弘樹; 辻 隆之; 熊谷 寛之; 中村 浩彰; 開發 謙次; 七星 雅一; 角谷 誠; 清水 宏紀; 大西 祥男
    第198回日本内科学会 近畿地方会 2012年09月 口頭発表(一般)
  • 心電図・心エコー図検査において,たこつぼ型心筋症が疑われた冠動脈塞栓症の一例  [通常講演]
    岡田武哲; 石田明彦; 姜臣鎬; 中村浩彰; 松添弘樹; 矢坂義則
    第111回 日本循環器学会近畿地方会 2011年06月 口頭発表(一般)
  • Bare metal stent(BMS)再狭窄部位の組織をOCTと病理標本で評価した一例
    石田明彦; 姜臣鎬; 岡田武哲; 中村浩彰; 松添弘樹; 矢坂義則
    第111回 日本循環器学会近畿地方会 2011年06月 口頭発表(一般)
  • 慢性心不全における夜間低酸素血症と心房細動の関係
    中村浩彰; 松添弘樹; 岡田武哲; 姜臣鎬; 石田明彦; 矢坂義則
    第111回 日本循環器学会近畿地方会 2011年06月 口頭発表(一般)
  • MPO ANCA 陽性を示した心筋障害の一例  [通常講演]
    松添弘樹; 姜臣鎬; 中村浩彰; 岡田武哲; 石田明彦; 矢坂義則
    第 111 回日本循環器学会 近畿地方会 2011年06月 口頭発表(一般)
  • 抗プロラクチン療法を施行した周産期心筋症の一例  [通常講演]
    松添弘樹 姜臣鎬 中村浩彰 岡田武哲 石田明彦 矢坂義則
    第 110 回日本循環器学会 近畿地方会 2010年11月 口頭発表(一般)

MISC

  • A Minimally Invasive Coil Embolization for Significant Left-to-Right Shunts Due to Giant Coronary-to-Pulmonary Artery Fistulas(タイトル和訳中)
    名村 咲音; 小西 弘樹; 小田 奈央; 野杁 純一; 竹重 遼; 松添 弘樹; 松本 晃典; 西尾 亮; 小澤 牧人; 松本 大典; 高石 博史; 山本 浩詞 日本循環器学会学術集会抄録集 87回 CROJ17 -1 2023年03月
  • 急性心不全患者の入院後72時間尿量と入院後ADL低下についての検討
    名村 咲音; 西尾 亮; 野杁 純一; 竹重 遼; 小西 弘樹; 松添 弘樹; 松本 晃典; 小澤 牧人; 松本 大典; 高石 博史 日本心臓病学会学術集会抄録 70回 O -4 2022年09月
  • 遺伝性プロテインC欠乏症2症例に同定された2つの新規遺伝子変異
    大森 健聖; 長屋 聡美; 冨樫 朋貴; 上田 凌央; 森屋 羽瑠雅; 目黒 牧子; 今井 湧太; 牧田 友香; 石束 光司; 松添 弘樹; 堀家 慎一; 森下 英理子 日本血栓止血学会誌 33 (2) 239 -239 2022年05月
  • 剖検で巨細胞性心筋炎の診断に至った難治性多形性心室頻拍の一例
    衣川 謙; 小西 弘樹; 松添 弘樹; 松本 大典; 高石 博史 日本心臓病学会学術集会抄録 69回 O -221 2021年09月
  • 下壁心筋梗塞後のVSDによるショックを起こし、救命できた1例
    長澤 圭典; 松本 大典; 松添 弘樹; 小西 弘樹; 西尾 亮; 小澤 牧人; 田中 康史; 佐藤 俊輔; 莇 隆; 高石 博史 日本心血管インターベンション治療学会抄録集 29回 546 -546 2021年02月
  • Hidekazu Tanaka; Kazuhiro Tatsumi; Hiroki Matsuzoe; Kensuke Matsumoto; Ken-ichi Hirata JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 75 (11) 731 -731 2020年03月
  • 静脈血栓塞栓症に対する抗凝固療法におけるビタミンK拮抗薬(warfarin)と直接作用型経口抗凝固薬(DOAC)の比較検討
    野杁 純一; 西尾 亮; 長澤 圭典; 松添 弘樹; 小澤 牧人; 田中 康史; 松本 大典; 高石 博史 日本心臓病学会学術集会抄録 67回 O -127 2019年09月
  • 浅大腿動脈のバイアバーン留置後にdistal edgeにfocalな閉塞を起こし、血栓を伴わない閉塞を生じた1例
    長澤 圭典; 松本 大典; 松添 弘樹; 西尾 亮; 小澤 牧人; 田中 康史; 佐藤 俊輔; 莇 隆; 高石 博史 日本心血管インターベンション治療学会抄録集 28回 [MO147 -004] 2019年09月
  • 肺高血圧症における三尖弁閉鎖不全症と長期予後との関係
    向井 淳; 田中 秀和; 佐野 浩之; 高田 裕基; 曽我 文隆; 羽溪 優; 畑澤 圭子; 松添 弘樹; 松本 賢亮; 平田 健一 日本心臓病学会学術集会抄録 66回 EP -220 2018年09月
  • M. Suto; K. Matsumoto; N. Shibata; S. Yokota; J. Mukai; E. Hisamatsu; H. Takada; F. Soga; K. Dokuni; Y. Hatani; K. Hatazawa; H. Matsuzoe; H. Tanaka; K. Hirata EUROPEAN HEART JOURNAL 39 314 -314 2018年08月
  • 肺高血圧症における三尖弁閉鎖不全症と長期予後との関係
    向井 淳; 田中 秀和; 佐野 浩之; 高田 裕基; 曽我 文隆; 羽渓 優; 畑澤 圭子; 松添 弘樹; 松本 賢亮; 平田 健一 超音波医学 45 (Suppl.) S556 -S556 2018年04月
  • 透析用シャントを閉鎖することで劇的な僧帽弁閉鎖不全症の改善が得られた一例
    羽渓 優; 田中 秀和; 須藤 麻貴子; 向井 淳; 曽我 文隆; 高田 裕基; 畑澤 圭子; 松添 弘樹; 松本 賢介; 平田 健一 超音波医学 45 (Suppl.) S799 -S799 2018年04月
  • 2型糖尿病における体脂肪量と左室心筋長軸方向収縮機能障害の関連性(Association of Body Fat Mass with Left Ventricular Myocardial Systolic Longitudinal Dysfunction in Type 2 Diabetes Mellitus)
    羽渓 優; 田中 秀和; 望月 泰秀; 須藤 麻貴子; 横田 駿; 柴田 奈緒; 向井 淳; 高田 裕基; 曽我 文隆; 畑澤 圭子; 堂國 久美子; 松添 弘樹; 久松 恵理子; 松本 賢亮; 平田 健一 日本循環器学会学術集会抄録集 82回 OJ10 -3 2018年03月
  • 心房細動および著しい僧帽弁逆流を有する患者の短縮した僧帽弁後尖(Shortened Posterior Mitral Leaflet in Patients with Atrial Fibrillation and Significant Mitral Regurgitation)
    高田 裕基; 田中 秀和; 横田 駿; 柴田 奈緒; 向井 淳; 須藤 麻貴子; 曽我 文隆; 堂國 久美子; 羽渓 優; 松添 弘樹; 畑澤 圭子; 久松 恵理子; 松本 賢亮; 平田 健一 日本循環器学会学術集会抄録集 82回 PJ078 -1 2018年03月
  • Junichi Ooka; Hidekazu Tanaka; Kensuke Matsumoto; Jun Mukai; Makiko Suto; Hiroki Takada; Fumitaka Soga; Yutaka Hatani; Keiko Hatazawa; Hiroki Matsuzoe; Hiroyuki Sano; Yasuhide Mochizuki; Ken-ichi Hirata CIRCULATION 136 OJ -022 2017年11月
  • Hiroyuki Sano; Hidekazu Tanaka; Yoshiki Motoji; Jun Mukai; Makiko Suto; Hiroki Takada; Fumitaka Soga; Kumiko Dokuni; Yutaka Hatani; Hiroki Matsuzoe; Keiko Hatazawa; Junichi Ooka; Kensuke Matsumoto; Kazuhiko Nakayama; Noriaki Emoto; Ken-ichi Hirata CIRCULATION 136 2017年11月
  • Fumitaka Soga; Hidekazu Tanaka; Yasuhide Mochizuki; Jun Mukai; Makiko Suto; Hiroki Takada; Kumiko Dokuni; Yutaka Hatani; Hiroki Matsuzoe; Keiko Hatazawa; Junichi Ooka; Hiroyuki Sano; Eriko Hisamatsu; Kensuke Matsumoto; Ken-ichi Hirata CIRCULATION 136 PJ040 -2 2017年11月
  • 肺高血圧症患者における下肢陽圧負荷心エコー図検査の有用性
    佐野 浩之; 田中 秀和; 向井 淳; 須藤 麻貴子; 高田 裕基; 曽我 文隆; 堂國 久美子; 羽渓 優; 畑澤 圭子; 松添 弘樹; 大岡 順一; 松本 賢亮; 中山 和彦; 江本 憲昭; 平田 健一 日本心臓病学会学術集会抄録 65回 P -147 2017年09月
  • 血清リン値は重度大動脈弁狭窄症患者の総大動脈石灰化負荷量を予測する(Serum Phosphate Level Predicts Total Aortic Calcification Burden in Patients with Severe Aortic Stenosis)
    Terashita Daisuke; Mori Shunpei; Tahara Natsuko; Izawa Yu; Toba Takayoshi; Matsuzoe Hiroki; Matsumoto Kensuke; Tanaka Hidekazu; Ohtake Hiromasa; Shinke Toshiro; Nishii Tatsuya; Kono Atsushi; Fujiwara Sei; Hirata Ken-ichi 日本循環器学会学術集会抄録集 81回 OE -322 2017年03月
  • 経胸壁心エコーでの推定とCTでの計測による左室流出路面積の比較(Comparison of the Left Ventricular Outflow Tract Area Estimated by Transthoracic Echocardiography and Measured by Computed Tomography)
    Izawa Yu; Mori Shunpei; Tahara Natsuko; Terashita Daisuke; Toba Takayoshi; Fujiwara Sei; Matsuzoe Hiroki; Matsumoto Kensuke; Tanaka Hidekazu; Ohtake Hiromasa; Shinke Toshiro; Nishii Tatsuya; Kohno Atsushi; Hirata Ken-ichi 日本循環器学会学術集会抄録集 81回 PE -193 2017年03月
  • 駆出率が保持されたリンパ腫患者における左室機能と癌の病期および合併症との関連性(Association of Left Ventricular Function with Stages of Cancer and Concomitant Diseases in Patients with Lymphoma and Preserved Ejection Fraction)
    畑澤 圭子; 田中 秀和; 野中 顕子; 大菊 麻貴子; 向井 淳; 久松 恵理子; 曽我 文隆; 高田 裕基; 堂國 久美子; 羽渓 優; 松添 弘樹; 下浦 広之; 大岡 順一; 佐野 浩之; 望月 泰秀; 郡山 恵子; 松本 賢亮; 平田 健一 日本循環器学会学術集会抄録集 81回 PJ -232 2017年03月
  • 大動脈弁石灰化の密度は大動脈弁口面積に依存することなく大動脈弁狭窄の血行動態的重症度を予測する(Aortic Valve Calcification Density Predicts the Hemodynamic Severity of Aortic Stenosis Independently of Aortic Valve Area)
    鳥羽 敬義; 森 俊平; 田原 奈津子; 伊澤 有; 寺下 大輔; 松添 弘樹; 松本 賢亮; 田中 秀和; 大竹 寛雅; 藤原 征; 新家 俊郎; 西井 達矢; 河野 淳; 平田 健一 日本循環器学会学術集会抄録集 81回 PJ -386 2017年03月
  • 糖尿病において肥満が左室長軸方向の機能に及ぼす影響(Impact of Obesity on Left Ventricular Longitudinal Function in Diabetes Mellitus)
    須藤 麻貴子; 田中 秀和; 望月 泰秀; 向井 淳; 久松 恵理子; 高田 裕基; 曽我 文隆; 羽渓 優; 畑澤 圭子; 松添 弘樹; 下浦 広之; 大岡 順一; 佐野 浩之; 郡山 恵子; 松本 賢亮; 平田 健一 日本循環器学会学術集会抄録集 81回 PJ -503 2017年03月
  • 重症大動脈弁逆流症を有し左室駆出率が保持されている患者の術後左室機能不全の予測における心室-動脈カップリングの有用性(Utility of Ventriculo-arterial Coupling to Predict Post-operative Left Ventricular dysfunction in Patients with Severe Aortic Regurgitation and Preserved Left ventricular Ejection Fraction)
    大岡 順一; 田中 秀和; 松本 賢亮; 須藤 麻貴子; 向井 淳; 久松 恵理子; 高田 裕基; 曽我 文隆; 羽渓 優; 畑澤 圭子; 松添 弘樹; 下浦 広之; 佐野 浩之; 望月 泰秀; 郡山 恵子; 平田 健一 日本循環器学会学術集会抄録集 81回 PJ -506 2017年03月
  • Yasuhide Mochiduki; Hidekazu Tanaka; Hiroki Takada; Fumitaka Soga; Kumiko Dokuni; Yutaka Hatani; Keiko Hatazawa; Hiroki Matsuzoe; Hiroyuki Shimoura; Junichi Ooka; Hiroyuki Sano; Keiko Ryo-Koriyama; Kensuke Matsumoto; Ken-ichi Hirata CIRCULATION 134 2016年11月
  • Hiroyuki Sano; Hidekazu Tanaka; Yoshiki Motoji; Yuko Fukuda; Hiroki Takada; Fumitaka Soga; Yutaka Hatani; Hiroki Matsuzoe; Keiko Hatazawa; Hiroyuki Shimoura; Junichi Ooka; Keiko Ryo-Koriyama; Kensuke Matsumoto; Noriaki Emoto; Ken-ichi Hirata CIRCULATION 134 2016年11月
  • Yasuhide Mochizuki; Hidekazu Tanaka; Hiroki Takada; Fumitaka Soga; Kumiko Dokuni; Yutaka Hatani; Keiko Hatazawa; Hiroki Matsuzoe; Hiroyuki Shimoura; Junichi Ooka; Hiroyuki Sano; Keiko Ryo -Koriyama; Kensuke Matsumoto; Ken-ichi Hirata CIRCULATION 134 2016年11月
  • Yasuhide Mochiduki; Hidekazu Tanaka; Hiroki Takada; Fumitaka Soga; Kumiko Dokuni; Yutaka Hatani; Keiko Hatazawa; Hiroki Matsuzoe; Hiroyuki Shimoura; Junichi Ooka; Hiroyuki Sano; Keiko Ryo-Koriyama; Kensuke Matsumoto; Ken-ichi Hirata CIRCULATION 134 2016年11月
  • Yasuhide Mochizuki; Hidekazu Tanaka; Hiroki Takada; Fumitaka Soga; Kumiko Dokuni; Yutaka Hatani; Keiko Hatazawa; Hiroki Matsuzoe; Hiroyuki Shimoura; Junichi Ooka; Hiroyuki Sano; Keiko Ryo-Koriyama; Kensuke Matsumoto; Ken-ichi Hirata CIRCULATION 134 2016年11月
  • Junichi Ooka; Hidekazu Tanaka; Kensuke Matsumoto; Hiroki Takada; Fumitaka Soga; Yutaka Hatani; Keiko Hatazawa; Hiroki Matsuzoe; Hiroyuki Shimoura; Hiroyuki Sano; Yasuhide Mochizuki; Keiko Ryo-Koriyama; Ken-ichi Hirata CIRCULATION 134 2016年11月
  • Junichi Ooka; Hidekazu Tanaka; Kensuke Matsumoto; Hiroki Takada; Fumitaka Soga; Yutaka Hatani; Keiko Hatazawa; Hiroki Matsuzoe; Hiroyuki Shimoura; Hiroyuki Sano; Yasuhide Mochizuki; Keiko Ryo-Koriyama; Ken-ichi Hirata CIRCULATION 134 2016年11月
  • Hiroyuki Sano; Hidekazu Tanaka; Yoshiki Motoji; Yuko Fukuda; Hiroki Takada; Fumitaka Soga; Yutaka Hatani; Hiroki Matsuzoe; Keiko Hatazawa; Hiroyuki Shimoura; Junichi Ooka; Keiko Ryo-Koriyama; Kensuke Matsumoto; Noriaki Emoto; Ken-ichi Hirata CIRCULATION 134 2016年11月
  • 肺高血圧症患者における治療後の右室reverse remodelingを予測する因子の検討
    佐野 浩之; 田中 秀和; 福田 優子; 高田 裕基; 曽我 文隆; 羽渓 優; 畑澤 圭子; 松添 弘樹; 大岡 順一; 下浦 広之; 佐和 琢磨; 望月 泰秀; 郡山 恵子; 松本 賢亮; 江本 憲昭; 平田 健一 日本心臓病学会学術集会抄録 64回 P -083 2016年09月
  • 2次元スペックルトラッキング法でみた左室-左房連関に及ぼす糖尿病性腎症の影響
    望月 泰秀; 田中 秀和; 高田 裕基; 曽我 文隆; 堂國 久美子; 羽渓 優; 畑澤 圭子; 松添 弘樹; 大岡 順一; 佐野 浩之; 下浦 広之; 郡山 恵子; 松本 賢亮; 平田 健一 日本心臓病学会学術集会抄録 64回 P -282 2016年09月
  • 経カテーテル閉鎖術後の心房中隔欠損症患者の両室相互作用(Bi-ventricular Interaction in Patients with Atrial Septal Defect Following Transcatheter Closure)
    Hatani Yutaka; Tanaka Hidekazu; Sawa Takuma; Takada Hiroki; Soga Fumitaka; Hatazawa Keiko; Dokuni Kumiko; Matsuzoe Hiroki; Shimoura Hiroyuki; Ooka Junichi; Sano Hiroyuki; Mochizuki Yasuhide; Ryo Keiko; Matsumoto Kensuke; Ohtake Hiromasa; Shinke Toshiro; Hirata Ken-ichi Circulation Journal 80 (Suppl.I) 1282 -1282 2016年03月
  • 心不全患者の左室肥大に対する他のangiotensin II receptor blockerからolmesartanへの切換の効果(Effects of a Change-Over from Other Angiotensin II Receptor Blockers to Olmesartan on Left Ventricular Hypertrophy in Heart Failure Patients)
    Shimoura Hiroyuki; Tanaka Hidekazu; Matsumoto Kensuke; Mochizuki Yasuhide; Takada Hiroki; Soga Fumitaka; Hatani Yutaka; Hatazawa Keiko; Dokuni Kumiko; Matsuzoe Hiroki; Ooka Junichi; Sano Hiroyuki; Sawa Takuma; Ryo Keiko; Hirata Ken-ichi Circulation Journal 80 (Suppl.I) 1472 -1472 2016年03月
  • Bi-ventricular Interaction in Patients with Atrial Septal Defect Following Transcatheter Closure
    Yutaka Hatani; Hidekazu Tanaka; Takuma Sawa; Keiko Hatazawa; Kumiko Dokuni; Hiroki Matsuzoe; Hiroyuki Shimoura; Junichi Ooka; Hiroyuki Sano; Yoshiki Motoji; Yasuhide Mochizuki; Keiko Ryo; Kensuke Matsumoto; Hiromasa Otake; Toshiro Shinke; Ken-ichi Hirata 日本循環器学会学術集会抄録集 80回 2016年03月 [査読有り]
  • Effects of a Change-Over from Other Angiotensin II Receptor Blockers to Olmesartan on Left Ventricular Hypertrophy in Heart Failure Patients
    Hiroyuki Shimoura; Hidekazu Tanaka; Kensuke Matsumoto; Yasuhide Mochizuki; Hiroki Takada; Fumitaka Soga; Yutaka Hatani; Keiko Hatazawa; Kumiko Dokuni; Hiroki Matsuzoe; Junichi Ooka; Hiroyuki Sano; Takuma Sawa; Keiko Ryo; Ken-ichi Hirata 日本循環器学会学術集会抄録集 80回 2016年03月 [査読有り]
  • 経皮的心房中隔欠損閉鎖術前後における両心室間の相互作用について(Ventricular Interaction in Patients with Atrial Septal Defect Following Transcatheter Closure)
    羽渓 優; 松本 賢亮; 田中 秀和; 佐和 琢磨; 高田 裕基; 曽我 文隆; 畑澤 圭子; 松添 弘樹; 下浦 広之; 大岡 順一; 佐野 浩之; 望月 泰秀; 漁 恵子; 新家 俊郎; 平田 健一 日本成人先天性心疾患学会雑誌 5 (1) 135 -135 2016年01月
  • Increasing Stimulus Strength of Coronary Sinus Pacing Improved Left Ventricular Mechanical Dyssynchrony and Contractile Function in Patients with Reduced Ejection Fraction
    Kazuhiro Tatsumi; Hidekazu Tanaka; Kensuke Matsumoto; Dokuni Kumiko; Yutaka Hatani; Keiko Hatazawa; Hiroaki Matsuzoe; Junichi Ooka; Hiroyuki Sano; Hiroyuki Shimoura; Takuma Sawa; Yoshiki Motoji; Yasuhide Mochizuki; Keiko Ryo; Koji Fukuzawa; Ken-ichi Hirata CIRCULATION 132 2015年11月
  • Junichi Ooka; Hidekazu Tanaka; Yutaka Hatani; Keiko Hatazawa; Kumiko Dokuni; Hiroki Matsuzoe; Hiroyuki Shimoura; Hiroyuki Sano; Yoshiki Motoji; Yasuhide Mochizuki; Keiko Ryo; Kensuke Matsumoto; Ken-ichi Hirata CIRCULATION 132 2015年11月
  • Keiko Ryo; Hidekazu Tanaka; Kumiko Dokuni; Yutaka Hatani; Hiroki Matsuzoe; Keiko Hatazawa; Hiroyuki Shimoura; Hiroyuki Sano; Takuma Sawa; Yasuhide Mochizuki; Yoshiki Motoji; Kazuhiro Tatsumi; Kensuke Matsumoto; Ken-ichi Hirata CIRCULATION 132 2015年11月
  • 骨形成不全症に合併した大動脈弁閉鎖不全症の1例
    曽我文隆; 田中秀和; 望月泰秀; 高田裕基; 羽渓優; 松添弘樹; 畑澤圭子; 堂國久美子; 下浦広之; 佐野浩之; 大岡順一; 佐和琢磨; 元地由樹; 漁恵子; 松本賢亮; 平田健一 第42回日本超音波医学会関西地方会抄録 2015年09月 [査読有り]
  • 心臓突然死の予知と予防の最前線 軽度心機能低下症例における致死性心室性不整脈の予測 左室心筋収縮の不均一性の評価
    田中 秀和; 松添 弘樹; 平田 健一 日本心臓病学会学術集会抄録 63回 305 -305 2015年09月 [査読有り]
  • 糖尿病性心筋症と糖尿病性神経症との関連性
    望月 泰秀; 田中 秀和; 堂國 久美子; 羽渓 優; 畑澤 圭子; 松添 弘樹; 下浦 広之; 佐野 浩之; 大岡 順一; 佐和 琢磨; 元地 由樹; 漁 恵子; 松本 賢亮; 平田 健一 日本心臓病学会学術集会抄録 63回 346 -346 2015年09月 [査読有り]
  • 軽度左室収縮能低下患者における右室ペーシングの影響
    大岡 順一; 田中 秀和; 堂國 久美子; 羽渓 優; 畑澤 圭子; 松添 弘樹; 下浦 広之; 佐野 浩之; 佐和 琢磨; 元地 由樹; 望月 泰秀; 漁 恵子; 松本 賢亮; 福沢 公二; 平田 健一 日本心臓病学会学術集会抄録 63回 712 -712 2015年09月
  • 右室中隔ペーシングにより高度左室心筋障害ならびに三尖弁閉鎖不全症を来した1例
    羽渓 優; 田中 秀和; 堂國 久美子; 畑澤 圭子; 松添 弘樹; 下浦 広之; 大岡 順一; 佐野 浩之; 土岐 啓己; 佐和 琢磨; 望月 泰秀; 元地 由樹; 漁 恵子; 松本 賢亮; 福沢 公二; 平田 健一 日本心臓病学会学術集会抄録 63回 1127 -1127 2015年09月
  • Impact of Albuminuria on Subclinical Left Ventricular Dysfunction in Patients with Diabetic Mellitus and Preserved Left Ventricular Ejection Fraction
    Yasuhide Mochizuki; Hidekazu Tanaka; Kumiko Dokumi; Yutaka Hatani; Keiko Hatazawa; Hiroki Matsuzoe; Hiromi Toki; Hiroyuki Shimoura; Junichi Ooka; Hiroyuki Sano; Takuma Sawa; Yoshiki Motoji; Keiko Ryo; Kensuke Matsumoto; Ken-ichi Hirata 日本循環器学会学術集会抄録集 82回 2015年04月 [査読有り]
  • Association of Microvascular Complications with Left Ventricular Longitudinal Function in Patients with Diabetes Mellitus and Preserved Left Ventricular Ejection Fraction
    Yasuhide Mochizuki; Hidekazu Tanaka; Kumiko Dokumi; Yutaka Hatani; Keiko Hatazawa; Hiroki Matsuzoe; Hiromi Toki; Hiroyuki Shimoura; Junichi Ooka; Hiroyuki Sano; Takuma Sawa; Yoshiki Motoji; Keiko Ryo; Kensuke Matsumoto; Ken-ichi Hirata 日本循環器学会学術集会抄録集 82回 2015年04月 [査読有り]
  • Combining of Right Ventricular Function with Mid-Term Reverse Remodeling in Right-Sided Heart Enhances Prognostic Capability for Pulmonary Hypertension Patient Outcome after Medical Treatment
    Hiroyuki Sano; Hidekazu Tanaka; Yoshiki Motoji; Yuko Fukuda; Kumiko Dokumi; Yutaka Hatani; Keiko Hatazawa; Hiroki Matsuzoe; Hiromi Toki; Hiroyuki Shimoura; Junichi Ooka; Takuma Sawa; Yasuhide Mochizuki; Keiko Ryo; Kensuke Matsumoto; Noriaki Emoto; Ken-ichi Hirata 日本循環器学会学術集会抄録集 82回 2015年04月 [査読有り]
  • Utility of Isovolumic Contraction Peak Velocity for Evaluation of Patient Status after Transcatheter Closure of Atrial Septal Defect in Adults
    Takuma Sawa; Hidekazu Tanaka; Mana Hiraishi; Yoshiki Motoji; Kumiko Dokuni; Yutaka Hatani; Keiko Hatazawa; Hiroki Matsuzoe; Hiromi Toki; Hiroyuki Shimoura; Junichi Ooka; Hiroyuki Sano; Yasuhide Mochizuki; Keiko Ryo; Kensuke Matsumoto; Toshiro Shinke; Ken-ichi Hirata 日本循環器学会学術集会抄録集 82回 2015年04月 [査読有り]
  • Association of Tricuspid Valve Geometry with Functional Tricuspid Regurgitation: Insights from Three-Dimensional Echocardiographic Analysis
    Keiko Ryo; Hidekazu Tanaka; Kumiko Dokuni; Yutaka Hanani; Hiroki Matsuzoe; Keiko Hatazawa; Hiroyuki Shimoura; Junichi Ooka; Hiromi Toki; Hiroyuki Sano; Takuma Sawa; Yasuhide Mochizuki; Yoshiki Motoji; Kensuke Matsumoto; Ken-ichi Hirata 日本循環器学会学術集会抄録集 82回 2015年04月 [査読有り]
  • 高電位冠状静脈洞ペーシングは駆出率低下患者の左室機械的同期不全を改善した(High Voltage Coronary Sinus Pacing Improved Left Ventricular Mechanical Dyssynchrony in Patients with Reduced Ejection Fraction)
    Tatsumi Kazuhiro; Tanaka Hidekazu; Matsumoto Kensuke; Inomata Kumiko; Hatani Yu; Hatazawa Keiko; Matsuzoe Hiroki; Ooka Junichi; Sano Hiroyuki; Shimoura Hiroyuki; Toki Hiromi; Sawa Takuma; Motoji Yoshiki; Mochizuki Yasuhide; Fukuda Yuko; Norisada Kazuko; Yoshida Akihiro; Hirata Ken-ichi Circulation Journal 79 (Suppl.I) 793 -793 2015年03月
  • 右室機能と中期的逆リモデリングを組み合わせることで肺高血圧症患者の内科治療後の転帰に関する予後予測能は向上する(Combining of Right Ventricular Function with Mid-Term Reverse Remodeling Enhances Prognostic Capability for Pulmonary Hypertension Patient Outcome after Medical Treatment)
    Sano Hiroyuki; Tanaka Hidekazu; Motoji Yoshiki; Fukuda Yuko; Doukuni Kumiko; Hatani Yutaka; Hatazawa Keiko; Matsuzoe Hiroki; Toki Hiromi; Shimoura Hiroyuki; Ooka Junichi; Sawa Takuma; Mochizuki Yasuhide; Ryo Keiko; Matsumoto Kensuke; Emoto Noriaki; Hirata Ken-ichi Circulation Journal 79 (Suppl.I) 1327 -1327 2015年03月
  • 左室駆出率が保持された糖尿病患者における微小血管合併症の左室長軸方向機能との関連性(Association of Microvascular Complications with Left Ventricular Longitudinal Function in Patients with Diabetes Mellitus and Preserved Left Ventricular Ejection Fraction)
    Mochizuki Yasuhide; Tanaka Hidekazu; Doukuni Kumiko; Hatani Yutaka; Hatazawa Keiko; Matsuzoe Hiroki; Toki Hiromi; Shimoura Hiroyuki; Ooka Junichi; Sano Hiroyuki; Sawa Takuma; Motoji Yoshiki; Ryo Keiko; Matsumoto Kensuke; Hirata Ken-ichi Circulation Journal 79 (Suppl.I) 1630 -1630 2015年03月
  • 三尖弁輪変形における機能的三尖弁閉鎖不全との関連性 三次元心エコー解析から得られた洞察(Association in the Tricuspid Annular Deformation with Functional Tricuspid Regurgitation: Insights from Three Dimensional Echocardiographic Analysis)
    Ryo Keiko; Tanaka Hidekazu; Inomata Kumiko; Hatani Yu; Hatazawa Keiko; Matsuzoe Hiroki; Shimoura Hiroyuki; Ooka Junichi; Toki Hiromi; Sano Hiroyuki; Sawa Takuma; Mochizuki Yasuhide; Motoji Yoshiki; Matsumoto Kensuke; Hirata Ken-ichi Circulation Journal 79 (Suppl.I) 1893 -1893 2015年03月
  • 左室駆出率が保持された糖尿病患者におけるアルブミン尿が無症候性左室機能不全に及ぼす影響(Impact of Albuminuria on Subclinical Left Ventricular Dysfunction in Patients with Diabetic Mellitus and Preserved Left Ventricular Ejection Fraction)
    Mochizuki Yasuhide; Tanaka Hidekazu; Doukuni Kumiko; Hatani Yutaka; Hatazawa Keiko; Matsuzoe Hiroki; Toki Hiromi; Shimoura Hiroyuki; Ooka Junichi; Sano Hiroyuki; Sawa Takuma; Motoji Yoshiki; Ryo Keiko; Matsumoto Kensuke; Hirata Ken-ichi Circulation Journal 79 (Suppl.I) 2405 -2405 2015年03月
  • 肺高血圧患者における右室収縮機能と左室充満の相互依存および転帰との関連(Interdependence of Right Ventricular Systolic Function and Left Ventricular Filling and its Association with Outcome in Patients with Pulmonary Hypertension)
    Motoji Yoshiki; Tanaka Hidekazu; Fukuda Yuko; Sano Hiroyuki; Ryo Keiko; Hatani Yu; Hatazawa Keiko; Matsuzoe Hiroki; Shimoura Hiroyuki; Toki Hiromi; Ooka Junichi; Sawa Takuma; Mochizuki Yasuhide; Matsumoto Kensuke; Emoto Noriaki; Hirata Ken-ichi Circulation Journal 79 (Suppl.I) 2882 -2882 2015年03月
  • 駆出率が軽度低下した患者における致死的心室性不整脈の決定因子としての左室協調運動障害と分散(Left Ventricular Dyssynergy and Dispersion as Determinant Factors of Fatal Ventricular Arrhythmias in Patients with Mild Reduced Ejection Fraction)
    Matsuzoe Hiroki; Tanaka Hidekazu; Matsumoto Kensuke; Dokuni Kumiko; Hatani Yutaka; Hatazawa Keiko; Toki Hiromi; Shimoura Hiroyuki; Ooka Junichi; Sano Hiroyuki; Sawa Takuma; Motoji Yoshiki; Mochizuki Yasuhide; Ryo Keiko; Fukuzawa Koji; Yoshida Akihiro; Hirata Ken-ichi Circulation Journal 79 (Suppl.I) 2942 -2942 2015年03月
  • 糖尿病患者における潜在性左室心筋障害と微小血管合併症との関連性
    望月泰秀; 田中秀和; 堂國久美子; 羽渓優; 畑澤圭子; 松添弘樹; 下浦広之; 佐野浩之; 大岡順一; 土岐啓己; 佐和琢磨; 元地由樹; 漁恵子; 松本賢亮; 平田健一 第26回 日本心エコー図学会学術集会抄録 2015年03月 [査読有り]
  • Yasuhide Mochizuki; Hidekazu Tanaka; Kumiko Doukuni; Yutaka Hatani; Keiko Hatazawa; Hiroki Matsuzoe; Hiromi Toki; Hiroyuki Shimoura; Junichi Ooka; Hiroyuki Sano; Takuma Sawa; Yoshiki Motoji; Keiko Ryo; Kensuke Matsumoto; Ken-ichi Hirata JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 65 (10) A1234 -A1234 2015年03月
  • Yoshiki Motoji; Hidekazu Tanaka; Yuko Fukuda; Keiko Ryo; Hiroyuki Sano; Kumiko Dokuni; Yutaka Hatani; Hiroyuki Shimoura; Keiko Hatazawa; Hiroki Matsuzoe; Hiromi Toki; Junichi Ooka; Takuma Sawa; Yasuhide Mochizuki; Kazuhiro Tatsumi; Kensuke Matsumoto; Noriaki Emoto; Ken-ichi Hirata JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 65 (10) A1532 -A1532 2015年03月
  • Hiroyuki Sano; Hidekazu Tanaka; Yoshiki Motoji; Yuko Fukuda; Kumiko Dokuni; Yutaka Hatani; Keiko Hatazawa; Hiroki Matsuzoe; Hiromi Toki; Hiroyuki Shimoura; Junichi Ooka; Takuma Sawa; Yasuhide Mochizuki; Keiko Ryo; Kensuke Matsumoto; Noriaki Emoto; Ken-ichi Hirata JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 65 (10) A1557 -A1557 2015年03月
  • 異なる治療戦略を選択した高齢者動脈管開存症の2症例
    松本 賢亮; 大岡 順一; 田中 秀和; 堂國 久美子; 羽渓 優; 畑澤 圭子; 松添 弘樹; 下浦 広之; 佐野 浩之; 土岐 啓己; 佐和 琢磨; 元地 由樹; 望月 泰秀; 漁 恵子; 平田 健一 日本成人先天性心疾患学会雑誌 4 (1) 154 -154 2015年01月
  • 血液培養陰性の疣腫により多発性脳梗塞と高度僧帽弁閉鎖不全症をきたした一例
    堂國 久美子; 松本 賢亮; 田中 秀和; 羽渓 優; 畑澤 圭子; 松添 弘樹; 下浦 広之; 大岡 順一; 佐野 浩之; 土岐 啓己; 佐和 琢磨; 元地 由樹; 望月 泰秀; 漁 恵子; 井上 武; 大北 裕; 平田 健一 第5回 日本心臓弁膜症学会学術集会抄録 2014年11月 [査読有り]
  • Efficacy of Combining Assessment of Right Ventricular Function and Right Atrial Remodeling as Prognostic Factor in Patients with Pulmonary Hypertension
    Yuko Fukuda; Hidekazu Tanaka; Yoshiki Motoji; Keiko Ryo; Hiroki Matsuzoe; Keiko Hatazawa; Yutaka Hatani; Kumiko Dokuni; Hiromi Toki; Hiroyuki Shimoura; Junichi Ooka; Hiroyuki Sano; Takuma Sawa; Yasuhide Mochizuki; Kazuhiro Tatsumi; Kensuke Matsumoto; Noriaki Emoto; Ken-ichi Hirata CIRCULATION 130 2014年11月 [査読有り]
  • Yuko Fukuda; Hidekazu Tanaka; Yoshiki Motoji; Keiko Ryo; Hiroki Matsuzoe; Keiko Hatazawa; Yutaka Hatani; Kumiko Dokuni; Hiromi Toki; Hiroyuki Shimoura; Junichi Ooka; Hiroyuki Sano; Takuma Sawa; Yasuhide Mochizuki; Kazuhiro Tatsumi; Kensuke Matsumoto; Noriaki Emoto; Ken-ichi Hirata CIRCULATION 130 2014年11月
  • Hiroyuki Sano; Hidekazu Tanaka; Yoshiki Motoji; Yuko Fukuda; Kumiko Dokuni; Yutaka Hatani; Keiko Hatazawa; Hiroki Matsuzoe; Hiromi Toki; Hiroyuki Shimoura; Junichi Ooka; Takuma Sawa; Yasuhide Mochizuki; Kazuhiro Tatsumi; Kensuke Matsumoto; Noriaki Emoto; Ken-ichi Hirata CIRCULATION 130 2014年11月
  • Hidekazu Tanaka; Yasunori Tsuboi; Kensuke Matsumoto; Kuniko Dokuni; Yutaka Hatani; Hiroki Matsuzoe; Keiko Hatazawa; Hiromi Toki; Hiroyuki Shimoura; Junichi Ooka; Hiroyuki Sano; Takuma Sawa; Yoshiki Motoji; Yasuhide Mochizuki; Kazuhiro Tatsumi; Yoshitada Sakai; Ken-ichi Hirata CIRCULATION 130 2014年11月
  • 大腿膝窩動脈領域における血管内治療の中期安全性と有効性(Safety and effectiveness of endovascular treatment for femoropopliteal lesions at 1year follow up period)
    Nakamura Hiroaki; Kadotani Makoto; Matsuzoe Hiroki; Hatazawa Keiko; Tsuji Takayuki; Inoue Mithihiko; Yasuda Tomoyuki; Nanahoshi Masakazu; Shimizu Hiroki; Ohnishi Yoshio 日本心血管インターベンション治療学会抄録集 23回 MP094 -MP094 2014年07月
  • 近位側深部静脈血栓症に対するカテーテル血栓溶解療法の安全性と中期有効性(Safety and effectiveness of catheter directed thrombolysis for proximal deep vein thrombosis at 12 months follow up period)
    Nakamura Hiroaki; Kadotani Makoto; Matsuzoe Hiroki; Tsuji Takayuki; Inoue Mitihiko; Yasuda Tomoyuki; Nanahoshi Masakazu; Shimizu Hiroki; Ohnishi Yoshio 日本心血管インターベンション治療学会抄録集 23回 MP301 -MP301 2014年07月
  • 特定の持続性心房細動患者における肺静脈隔離術のみによる良好な臨床成績(Favorable Clinical Outcome Only by Pulmonary Vein Isolation in Selected Persistent Atrial Fibrillation Patients)
    Takami Kaoru; Shimizu Hiroki; Kumagai Hiroyuki; Matsuzoe Hiroki; Hatazawa Keiko; Ohnishi Yoshio 心電図 34 (Suppl.3) 510 -510 2014年06月
  • 急性冠症候群発症時の血清および血栓中の脂肪酸組成(Serum and Thrombus Fatty Acid Composition at the Onset of Acute Coronary Syndrome)
    Yasuda Tomoyuki; Irino Yasuhiro; Shimizu Hiroki; Mori Kenta; Mori Takeshige; Hatazawa Keiko; Matsuzoe Hiroki; Tsuji Takayuki; Inoue Michihiko; Kumagai Hiroyuki; Takami Kaoru; Norisada Kazuko; Nakamura Hiroaki; Nanahoshi Masakazu; Kadotani Makoto; Toh Ryuji; Ishida Tatsuro; Hirata Ken-ichi; Ohnishi Yoshio Circulation Journal 78 (Suppl.I) 31 -32 2014年03月
  • 高血圧性心不全患者に対する全身性血管病変の検討
    井上 通彦; 清水 宏紀; 角谷 誠; 七星 雅一; 安田 知行; 伴 親徳; 中村 浩彰; 高見 薫; 則定 加津子; 熊谷 寛之; 辻 隆之; 松添 弘樹; 畑澤 圭子; 大西 祥男 日本心臓病学会誌 8 (Suppl.I) 482 -482 2013年09月
  • 末梢動脈疾患における腎機能障害の頻度
    中村 浩彰; 角谷 誠; 畑澤 圭子; 松添 弘樹; 辻 隆之; 井上 通彦; 熊谷 寛之; 高見 薫; 則定 加津子; 伴 親徳; 安田 知行; 七星 雅一; 清水 宏紀; 大西 祥男 日本心臓病学会誌 8 (Suppl.I) 495 -495 2013年09月
  • 重症石灰化を伴う大動脈狭窄に対して血管内治療が有効であった1症例(A case of endovascular therapy was effective for aorta stenosis with severe calcification)
    Nakamura Hiroaki; Kadotani Makoto; Hatazawa Keiko; Matsuzoe Hiroki; Tsuji Takayuki; Inoue Michihiko; Ban Chikanori; Kaihotsu Kenji; Nanahoshi Masakazu 日本心血管インターベンション治療学会誌 5 (Suppl.I) 609 -609 2013年05月
  • Biolimus溶出性ステント留置後の遅発性LMTステント血栓症の1症例(A case with late LMT stent thrombosis after biolimus-eluting stent implantation)
    Matsuzoe Hiroki; Kadotani Makoto; Nakamura Hiroaki; Ban Chikanori; Kaihotsu Kenji; Nanahoshi Masakazu 日本心血管インターベンション治療学会誌 5 (Suppl.I) 631 -631 2013年05月
  • 重度石灰化RCA CTOの治療は困難であった(It has been difficult to treat heavy calcified RCA CTO)
    Ban Chikanori; Kadotani Makoto; Kaihotsu Kenji; Hatazawa Keiko; Matsuzoe Hiroki; Tsuji Takayuki; Inoue Michihiko; Kumagai Hiroyuki; Takami Kaoru; Norisada Kazuko; Nakamura Hiroaki; Nanahoshi Masakazu; Shimizu Hiroki; Oonishi Yoshio 日本心血管インターベンション治療学会誌 5 (Suppl.I) 694 -694 2013年05月
  • 末梢動脈疾患患者における慢性閉塞性肺疾患の有病率(The Prevalence of Chronic Obstructive Pulmonary Disease in Patients with Peripheral Artery Disease)
    Nakamura Hiroaki; Shimizu Hiroki; Hatazawa Keiko; Matsuzoe Hiroki; Tsuji Takayuki; Inoue Michihiko; Kumagai Hiroyuki; Takami Kaoru; Norisada Kazuko; Ban Chikanori; Kaihotsu Kenji; Nanahoshi Masakazu; Kadotani Makoto; Ohnishi Yoshio Circulation Journal 77 (Suppl.I) 225 -225 2013年03月
  • 心房細動に対する高周波アブレーション施行患者におけるdabigatranとwarfarinの有効性と安全性(Efficacy and Safety of Dabigatran Versus Warfarin in Patients with Undergoing Radiofrequency Ablation for Atrial Fibrillation)
    Takahasi Tomohisa; Shimizu Hiroki; Hatazawa Keiko; Matsuzoe Hiroki; Tsuji Takayuki; Inoue Michihiko; Kumagai Hiroyuki; Takami Kaoru; Norisada Kazuko; Nakamura Hiroaki; Ban Chikanori; Nanahoshi Masakazu; Kadotani Makoto; Shimizu Hiroki; Ohnishi Yoshio Circulation Journal 77 (Suppl.I) 237 -237 2013年03月
  • 巨大右心房内血栓症から両肺の肺動脈血栓塞栓症をきたした1例
    足立 靖; 松添 弘樹; 川田 交俊; 高津 宏樹; 生田 寿彦; 石田 明彦; 中野 麗香; 山内 壮作; 下 智比古; 池原 進 日本病理学会会誌 101 (2) 62 -62 2012年09月

受賞

  • 2016年11月 日本循環器学会 第122回日本循環器学会近畿地方会 YIA 優秀賞
  • 2013年03月 日本循環器学会/日本心臓財団 2012年「心臓」賞 優秀賞

共同研究・競争的資金等の研究課題

  • 日本学術振興会:科学研究費助成事業
    研究期間 : 2016年10月 -2019年03月 
    代表者 : 松本 賢亮; 田中 秀和; 松添 弘樹
     
    120名の心不全患者および20名の正常者に対して下肢陽圧負荷エコー検査を施行した。正常者では、下肢陽圧に対して充満圧の上昇なしに20%の駆出血流の増大が得られた。一方心不全患者では、負荷に対して充満圧の上昇といった犠牲を払いながら駆出量の10%の増大反応を示した。経過観察期間の20ヶ月間において、120名の心不全患者のうち、30名の患者において心血管イベントが発生した。イベントを起こさなかった心不全群では、下肢陽圧負荷により軽度の左室充満圧上昇はあるものの、前方駆出量の有意な増大反応が見られた。一方、イベントを起こした群では、左室充満圧の著明な上昇と、前方駆出量増大反応の低下が認められた。

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