![](https://www.kindai.ac.jp/data/images/professor/2121.jpg)
稲村 昇(イナムラ ノボル)
医学科 | 教授 |
Last Updated :2024/08/31
■教員コメント
報道関連出演・掲載一覧
<報道関連出演・掲載一覧>
●2021/9/23
読売テレビ「朝生ワイドす・またん!」
5Gを活用し、胎児心臓エコー映像をリアルタイム伝送する実証実験について
●2021/9/22
NHK「ニュースほっと関西」読売テレビ「かんさい情報ネットten.」
朝日放送「キャスト」関西テレビ「報道ランナー」
5Gを活用し、胎児心臓エコー映像をリアルタイム伝送する実証実験が紹介について
●2018/5/30
毎日新聞(下に同じ)
●2018/5/25
読売新聞(下に同じ)
●2018/5/24
産経新聞・日本経済新聞・朝日新聞
・フジサンケイビジネスアイ(下に同じ)
●2018/5/23
共同通信ニュース
胎児遠隔診断で先天性心臓病の早期治療に成功
■研究者基本情報
J-Global ID
プロフィール
- 近畿大学医学部 小児科学教室講師
日本胎児心臓病学会理事長
近畿胎児心臓病研究会代表幹事
クリフム夫マタニテイクリニック顧問
■経歴
委員歴
■研究活動情報
受賞
- 2020年07月 近畿大学医学会 近畿大学医学会賞
Utility of the STIC method for diagnosing tachyarrhythmia in fetuses at 12 weeks’ gestational age - 2020年07月 日本小児循環器学会 Case Report Award
Utility of the STIC method for diagnosing tachyarrhythmia in fetuses at 12 weeks’ gestational age - 2020年04月 近畿大学医学部 2018年度 Good teacher 賞
- 2018年07月 日本小児循環器学会 高尾賞
受賞者: 稲村 昇 - 2011年01月 読売新聞社 第39回大阪府医療功労賞
受賞者: 稲村 昇 - 2010年02月 日本胎児心臓病学会 里見賞 チーム医療部門
受賞者: 稲村 昇 - 2007年11月 大阪府独立行政法人病院機構 優秀職員賞
受賞者: 稲村 昇 - 2007年07月 日本小児循環器学会 最優秀演題賞
受賞者: 稲村 昇 - 2006年10月 旭川医科大学 特別奨励賞
受賞者: 稲村 昇 - 2004年01月 日本Pediatric Interventional Cardiology学会 小池一行賞
受賞者: 稲村 昇
論文
- Keita Terui; Kouji Nagata; Masaya Yamoto; Yoshiaki Sato; Hiroomi Okuyama; Hidehiko Maruyama; Akiko Yokoi; Kiyokazu Kim; Kouji Masumoto; Tadaharu Okazaki; Noboru Inamura; Katsuaki Toyoshima; Yuhki Koike; Yuta Yazaki; Yasunori Sato; Noriaki UsuiPediatric surgery international 40 1 240 - 240 2024年08月PURPOSE: This study aimed to clarify surgical complications associated with open surgery for congenital diaphragmatic hernia (CDH). METHODS: We performed an exploratory data analysis of the clinical characteristics of surgical complications of neonates with CDH who underwent laparotomy or thoracotomy between 2006 and 2021. Data of these patients were obtained from the database of the Japanese CDH Study Group. RESULTS: Among 1,111 neonates with left or right CDH, 852 underwent open surgery (laparotomy or thoracotomy). Of these 852 neonates, 51 had the following surgical complications: organ injury (n = 48; 6% of open surgeries); circulatory failure caused by changes in the organ location (n = 2); and skin burns (n = 1). Injured organs included the spleen (n = 30; 62% of organ injuries), liver (n = 7), lungs (n = 4), intestine (n = 4), adrenal gland (n = 2), and thoracic wall (n = 2). Fourteen of the patients who experienced organ injury required a blood transfusion (2% of open surgeries). The adjusted odds ratio of splenic injury for patients with non-direct closure of the diaphragm was 2.2 (95% confidence interval, 1.1-4.9). CONCLUSION: Of the patients who underwent open surgery for CDH, 2% experienced organ injury that required a blood transfusion. Non-direct closure of the diaphragmatic defect was a risk factor for splenic injury.
- Noboru Inamura; Megumi Machida; Takako Nakamura; Kohtaro Uenishi; Ritsuko K PoohJournal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine 2024年06月BACKGROUND: Although the fetal sphericity index (SI) and fractional shortening (FS) of 24 transverse segments have been previously reported after the 20th gestational week, there have been no reports during the first and early second trimester. OBJECTIVE: This study aimed to clarify the SI and FS of 24 transverse segments in normal fetuses before the 20th gestational week. METHODS: A total of 101 normal fetuses aged between 12 and 20 gestational weeks were examined. The displacement of the ventricular endocardium during the cardiac cycle was computed using speckle-tracking software (GE Healthcare, Milwaukee, WI). We analyzed the length of 24 end-diastolic lateral segments and the end-diastolic basal (seg1-6)- middle (Seg7-15)-apical (Seg16-24) distribution from the base to the apex of each ventricle, according to the method described by DeVore et al. The SI and FS were computed for each of the 24 segments by dividing the mid-basal-apical length by the transverse size. RESULTS: The SI for each segment was independent of the gestational age. The SI of the right ventricle was significantly lower than that of the left ventricle for segments 1-14, suggesting that the right ventricle was more spherical than the left ventricle in the basal segment only. The FS of the right ventricle was significantly lower than that of the left ventricle in segments 1 to 2 and 13 to 24. CONCLUSION: The morphology of the ventricles before 20 weeks of gestation differs from that between 20 and 40 weeks of gestation. This difference may be related to myocardial densification or performance.
- 萩原 智; 上嶋 一臣; 西田 直生志; 依田 広; 三長 孝輔; 南 康範; 田北 雅弘; 青木 智子; 盛田 真弘; 千品 寛和; 松原 卓哉; 大丸 直哉; 稲村 昇; 工藤 正俊肝臓 64 11 567 - 574 (一社)日本肝臓学会 2023年11月症例は30代男性.幼少期に完全大血管転位III型に対してFontan手術が施行され,近医に定期的に通院していた.20XX年7月腹部USで多発肝腫瘤を指摘され当院紹介受診となった.造影CTにて最大13cmの多発肝細胞癌と判明した(BCLC stage B).画像上は門脈圧亢進所見や明らかな肝形態異常を認めなかったが,肝生検でCongestive Hepatic Fibrosis Score 3であり,実際には線維化の進展を認めていた.肝内多発のため外科手術やRFAの適応外であった.また最大径の腫瘍は肝外に突出しており,腹腔内破裂の危険性もあることから,まずTACEを施行した.再発に応じて各種抗癌剤治療を行い,生存中である.画像上は肝線維化を示唆する所見はなかったが,Fontan術後の特殊な循環動態では,肝線維化が進展している可能性があり,本症例を通して肝癌サーベイランスの重要性を再考する.(著者抄録)
- Tadaharu Okazaki; Keita Terui; Kouji Nagata; Masahiro Hayakawa; Hiroomi Okuyama; Shoichiro Amari; Kouji Masumoto; Masaya Yamoto; Noboru Inamura; Katsuaki Toyoshima; Taizo Furukawa; Manabu Okawada; Akiko Yokoi; Yuki Koike; Shuko Nojiri; Yuji Nishizaki; Naotake Yanagisawa; Noriaki UsuiJournal of perinatology : official journal of the California Perinatal Association 43 10 1295 - 1300 2023年10月OBJECTIVE: To assess the reliability of pulmonary artery (PA) parameters as a prognostic marker in neonates with isolated left-sided congenital diaphragmatic hernia (IL-CDH). STUDY DESIGN: A retrospective cohort study conducted by the Japanese CDH Study Group (JCDHSG). RESULTS: 323 IL-CDH patients registered with the JCDHSG were included. 272 patients survived to 90 days of age. Right PA (RPA) and left PA (LPA) diameters and pulmonary artery index (PAIndex) at birth were significantly larger in survivors. The cutoff values of RPA and LPA diameters and PAIndex for survival up to 90 days were 3.2 mm, 2.8 mm and 83.7, respectively, and logistic regression analysis showed that these were significantly related to survival. Multiple logistic regression analysis showed that both the PA parameters and liver herniation were significantly related to survival. CONCLUSIONS: The three PA parameters at birth can predict clinical outcomes and are considered as independent risk factors of liver herniation.
- Yousuke Imanishi; Noriaki Usui; Taizo Furukawa; Kouji Nagata; Masahiro Hayakawa; Shoichiro Amari; Akiko Yokoi; Kouji Masumoto; Masaya Yamoto; Tadaharu Okazaki; Noboru Inamura; Katsuaki Toyoshima; Keita Terui; Hiroomi OkuyamaJournal of perinatology : official journal of the California Perinatal Association 43 7 884 - 888 2023年04月OBJECTIVES: To evaluate the survival and intact-survival rates among preterm infants with congenital diaphragm hernia (CDH). STUDY DESIGN: Multicenter retrospective cohort study of 849 infants born between 2006 and 2020 at 15 Japanese CDH study group facilities. Multivariate logistic regression analysis adjusted using inverse probability treatment weighting (IPTW) method was used. We also compare trends of intact-survival rates among term and preterm infants with CDH. RESULTS: After adjusting using the IPTW method for CDH severity, sex, APGAR score at 5 min, and cesarean delivery, gestational age and survival rates have a significantly positive correlation [coefficient of determination (COEF) 3.40, 95% confidence interval (CI), 1.58-5.21, p value <0.001] and higher intact-survival rate [COEF 2.39, 95% CI, 1.73-4.06, p value 0.005]. Trends of intact-survival rates for both preterm and term infants had significantly changed, but improvement in preterm infants was much smaller than in term infants. CONCLUSION: Prematurity was a significant risk factor for survival and intact-survival among infants with CDH, regardless of adjustment for CDH severity.
- Hidehiko Maruyama; Shoichiro Amari; Yutaka Kanamori; Masahiro Hayakawa; Kouji Nagata; Yuta Yazaki; Yoshihiko Taniyama; Kazunori Masahata; Masaya Yamoto; Keita Terui; Kiyokazu Kim; Yuhki Koike; Tadaharu Okazaki; Noboru Inamura; Noriaki UsuiJournal of pediatric surgery 2023年03月BACKGROUND: Congenital diaphragmatic hernia (CDH) is a severe congenital disease. Some CDH infants suffer from gastro-esophageal reflux disease (GERD), even after surgical correction of gastric position. A transpyloric tube (TPT) is inserted into CDH patients under direct observation intraoperatively in some hospitals in Japan to establish early enteral feeding. This strategy avoids gastric expansion to maintain a better respiratory condition. However, it is unclear whether the strategy has a secure effect for patient prognosis. This study aimed to evaluate the effectiveness of intraoperative TPT insertion on enteral feeding and postoperative weight gain. METHODS: The Japanese CDH Study Group database was used to identify infants with CDH born between 2011 and 2016, who were then divided into two groups: the TPT group and gastric tube (GT) group. In the TPT group, infants underwent intraoperative TPT insertion; postoperative insertion/extraction of TPT was irrelevant to the analysis. Weight growth velocity (WGV) was calculated using the exponential model. Subgroup analysis was performed using Kitano's gastric position classification. RESULTS: We analyzed 204 infants, of which 99 and 105 were in the TPT and GT groups, respectively. Enteral nutrition (EN) in the TPT and GT groups was 52 ± 39 and 44 ± 41 kcal/kg/day (p = 0.17) at age 14 days (EN14), respectively, and 83 ± 40 and 78 ± 45 kcal/kg/day (p = 0.46) at age 21 days (EN21), respectively. WGV30 (WGV from day 0 to day 30) in the TPT and GT groups was 2.3 ± 3.0 and 2.8 ± 3.8 g/kg/day (p = 0.30), respectively, and WGV60 (WGV from day 0 to day 60) was 5.1 ± 2.3 and 6.0 ± 2.5 g/kg/day (p = 0.03), respectively. In infants with Kitano's Grade 2 + 3, EN14 in the TPT and GT groups was 38 ± 35 and 29 ± 35 kcal/kg/day (p = 0.24), respectively, EN21 was 73 ± 40 and 58 ± 45 kcal/kg/day (p = 0.13), respectively, WGV30 was 2.3 ± 3.2 and 2.0 ± 4.3 g/kg/day (p = 0.76), respectively, and WGV60 was 4.6 ± 2.3 and 5.2 ± 2.3 g/kg/day (p = 0.30), respectively. CONCLUSION: Intraoperative TPT insertion did not improve nutritional intake and WGV30. WGV60 in TPT was less than that in GT. In Grade 2 + 3 subgroup analysis, TPT also had no advantage. We could not recommend routine TPT insertion at surgery. LEVEL OF EVIDENCE: III.
- Kana Maeda; Satoshi Marutani; Kohsuke Nishi; Kazushi Ueshima; Nori Imaoka; Keisuke Sugimoto; Noboru InamuraInternal medicine (Tokyo, Japan) 2023年03月We encountered two consecutive cases of adult-onset Kawasaki disease (AKD) that were difficult to diagnose. In both cases, Kawasaki disease was not considered as a differential diagnosis in the early stages. However, it was possible to make a diagnosis by citing the disease as a differential diagnosis and introducing the patients to the pediatrics department. AKD has a minimal incidence rate and may have a clinical course different from that of childhood-onset Kawasaki disease. Therefore, it is necessary to incorporate Kawasaki disease into the differentiation of an adult fever and to consult with a pediatrician for its diagnosis.
- Tomiko Toyokawa; Noboru Inamura; Yukiko Kawazu; Futoshi KayataniPediatrics international : official journal of the Japan Pediatric Society 65 1 e15480 2023年01月
- Y. Matsubara; N. Inamura; N. Takada; T. FujitaUltrasound in Obstetrics & Gynecology 2023年01月
- Nobuyoshi Kusano; Satoshi Marutani; Kazuhiko Ishimaru; Takao Sato; Keisuke Sugimoto; Noboru InamuraPediatric and Developmental Pathology 109352662211396 - 109352662211396 2022年12月Coronary aneurysm secondary to coronary fistula is a rare condition, with no existing report on its pathological examination. We report the case of a patient diagnosed with a right coronary artery fistula with coronary aneurysm during the fetal period. During follow-up after delivery, the aneurysm became larger, even though the shunt size decreased. We were afraid the aneurysm would rupture and therefore, planned elective catheter embolization. At the age of 4 years, the patient underwent surgery, which involved closing the fistula and making the lumen of the aneurysm smaller. However, the surgery was not catheter embolization as planned because segment 3 branched off from the largest aneurysm where we planned to embolize. Pathologically, the structure of the coronary artery differed from that of a healthy one, with thickened intima and media, fewer scattered smooth muscle cells, widely distributed elastic fibers, and mucoid degeneration in the media. The structure of the coronary artery suggested that the vessel wall was weak and that the aneurysm would rupture if not treated. Postoperative coronary angiography showed that segment 2 was obstructed, while the collaterals from the left coronary artery perfused the area. We could have treated the fistula with a catheter as scheduled.
- Keita Terui; Kouji Nagata; Masaya Yamoto; Masahiro Hayakawa; Hiroomi Okuyama; Shoichiro Amari; Akiko Yokoi; Taizo Furukawa; Kouji Masumoto; Tadaharu Okazaki; Noboru Inamura; Katsuaki Toyoshima; Yuhki Koike; Manabu Okawada; Yasunori Sato; Noriaki UsuiPediatric surgery international 39 1 4 - 4 2022年11月PURPOSE: To develop a predictive score for small diaphragmatic defects in infants with congenital diaphragmatic hernia (CDH) for determining thoracoscopic surgery indication. METHODS: The Japanese CDH Study Group cohort was randomly divided into derivation (n = 397) and validation (n = 396) datasets. Using logistic regression, a prediction model and weighted scoring system for small diaphragmatic defects were created from derivation dataset and validated with validation dataset. RESULTS: Six weighted variables were selected: no hydramnios, 1 point; 1 min Apgar score of 5-10, 1 point; apex type of the lung (left lung is detected radiographically in apex area), 1 point; oxygenation index < 8, 1 point; abdominal nasogastric tube (tip of the nasogastric tube is detected radiographically in the abdominal area), 2 points; no right-to-left flow of ductus arteriosus, 1 point. In validation dataset, rates of small diaphragmatic defects for Possible (0-3 points), Probable (4-5 points), and Definite (6-7 points) groups were 36%, 81%, and 94%, respectively (p < 0.001). Additionally, sensitivity, specificity, positive predictive value, and C statistics were 0.78, 0.79, 0.88, 0.76, and 0.45, 0.94, 0.94, 0.70 for Probable and Definite groups, respectively. CONCLUSION: Our scoring system effectively predicted small diaphragmatic defects in infants with CDH.
- T. Miyoshi; Y. Maeno; T. Matsuda; Y. Ito; N. Inamura; K.‐S. Kim; I. Shiraishi; K. Kurosaki; T. Ikeda; H. Sago; H. Horigome; H. Yoda; S. Tsukahara; Y. Teramachi; K. Takahashi; K. Toyoshima; M. Nakai; S. KatsuragiUltrasound in Obstetrics & Gynecology 61 1 49 - 58 2022年11月
- Kota Yoneda; Shoichiro Amari; Masashi Mikami; Keiichi Uchida; Akiko Yokoi; Manabu Okawada; Taizo Furukawa; Katsuaki Toyoshima; Noboru Inamura; Tadaharu Okazaki; Masaya Yamoto; Kouji Masumoto; Keita Terui; Hiroomi Okuyama; Masahiro Hayakawa; Tomoaki Taguchi; Noriaki Usui; Tetsuya IsayamaPediatric pulmonology 58 1 152 - 160 2022年09月BACKGROUND: Mortality prediction of congenital diaphragmatic hernia (CDH) is essential for developing treatment strategies, including fetal therapy. Several researchers have reported prognostic factors for this rare but life-threatening condition; however, the optimal combination of prognostic factors remains to be elucidated. OBJECTIVES: This study aimed to develop the most discriminative prenatal and postnatal models to predict the mortality of infants with an isolated left-sided CDH. METHODS: This multi-institutional retrospective cohort study included infants with CDH born at 15 tertiary hospitals of the Japanese CDH Study Group between 2011 and 2016. We developed multivariable logistic models with every possible combination of predictors and identified models with the highest cross-validated area under the receiver operating characteristic curve (AUC) for prenatal and postnatal predictions. RESULTS: Among 302 eligible infants, 44 died before discharge. The prenatal mortality prediction model was based on the observed/expected lung area to head circumference ratio (O/E LHR), liver herniation, and stomach herniation (AUC, 0.830). The postnatal mortality prediction model was based on O/E LHR, liver herniation, and the lowest oxygenation index (AUC, 0.944). CONCLUSION: Our models can facilitate the prenatal and postnatal mortality prediction of infants with isolated left-sided CDH.
- Jun Kono; Kouji Nagata; Keita Terui; Shoichiro Amari; Katsuaki Toyoshima; Noboru Inamura; Yuhki Koike; Masaya Yamoto; Tadaharu Okazaki; Yuta Yazaki; Hiroomi Okuyama; Masahiro Hayakawa; Taizo Furukawa; Kouji Masumoto; Akiko Yokoi; Noriaki Usui; Tatsuro TajiriPediatric surgery international 38 12 1873 - 1880 2022年09月PURPOSE: The prenatal diagnosis of the stomach position in congenital diaphragmatic hernia (CDH) has been a reliable prognostic factor, but few studies have focused on the postnatal position. We therefore evaluated the significance of the nasogastric (NG) tube position just after birth. METHODS: The Japanese CDH Study Group database enrolled 1037 CDH neonates over 15 years. In our multicenter retrospective study, 464 cases of left-sided isolated CDH with prenatal diagnoses were divided into two groups: NG tube below the diaphragm (BD; n = 190) or above the diaphragm (AD; n = 274). The primary outcome was the 90-day survival rate, and the secondary outcomes were mechanical ventilation duration, hospitalization duration, and recurrence rate. RESULTS: The BD group had a significantly higher 90-day survival rate (98.4 vs. 89.4%, p < 0.001), shorter mechanical ventilation (11 vs. 19 days, p < 0.001), shorter hospitalization (38 vs. 59 days, p < 0.001), and lower recurrence rate (p = 0.002) than the AD group. A multivariate analysis showed that BD (adjusted odds ratio, 3.68; 95% confidence interval 1.02-13.30) was a favorable prognostic factor for the 90-day survival. CONCLUSION: The assessment of the NG tube position revealed it to be a reliable prognostic factor of left-sided isolated CDH. Therefore, it should be included as a routine assessment.
- Kazunori Masahata; Masaya Yamoto; Satoshi Umeda; Kouji Nagata; Keita Terui; Makoto Fujii; Masayuki Shiraishi; Masahiro Hayakawa; Shoichiro Amari; Kouji Masumoto; Tadaharu Okazaki; Noboru Inamura; Katsuaki Toyoshima; Yuki Koike; Taizo Furukawa; Yuta Yazaki; Akiko Yokoi; Masayuki Endo; Yuko Tazuke; Hiroomi Okuyama; Noriaki UsuiPediatric surgery international 38 12 1745 - 1757 2022年09月 [査読有り]
PURPOSE: This study aimed to evaluate prenatal predictors of mortality in fetuses with congenital diaphragmatic hernia (CDH). METHODS: A systematic literature search was performed to identify relevant observational studies that evaluated the ability of lung-to-head ratio (LHR), observed-to-expected LHR (o/e-LHR), observed-to-expected total fetal lung volume (o/e-TFLV), lung-to-thorax transverse area ratio (L/T ratio), intrathoracic herniation of the liver and the stomach, and side of diaphragmatic hernia, using a threshold for the prediction of mortality in fetuses with CDH. Study quality was assessed using the QUADAS-2 tool. Hierarchical summary receiver operating characteristic curves were constructed. RESULTS: A total of 50 articles were included in this meta-analysis. The QUADAS-2 tool identified a high risk of bias in more than one domain scored in all parameters. Among those parameters, the diagnostic odds ratio of mortality with o/e-LHR < 25%, o/e-TFLV < 25%, and L/T ratio < 0.08 were 11.98 [95% confidence interval (CI) 4.65-30.89], 11.14 (95% CI 5.19-23.89), and 10.28 (95% CI 3.38-31.31), respectively. The predictive values for mortality were similar between the presence of liver herniation and retrocardiac fetal stomach position. CONCLUSIONS: This systematic review suggests that o/e-LHR, o/e-TFLV, and L/T ratio are equally good predictors of neonatal mortality in fetuses with isolated CDH. - 胎児心エコー検査ガイドライン改定を今後の診療に活かすために 胎児心エコー検査ガイドライン改定のポイントと活用方法稲村 昇; 堀米 仁志; 瀧聞 浄宏; 渋谷 和彦; 与田 仁志; 河津 由紀子; 廣野 恵一日本小児循環器学会総会・学術集会抄録集 58回 [I - 01] (NPO)日本小児循環器学会 2022年07月
- Yayoi Matsubara; Daisuke Fujita; Noboru Inamura; Tomio FujitaJournal of medical ultrasonics (2001) 49 3 451 - 461 2022年07月PURPOSE: The objective of our study was to compare and consider reference values of fetal atrioventricular (AV) intervals as measured by four different pulsed Doppler wave techniques (left ventricular inflow/outflow [LV in/out], pulmonary vein/pulmonary artery [PV/PA], innominate vein/ascending aorta [InnV/AA], and supra vena cava/ascending aorta [SVC/AA]) in pregnant women with anti-SSA/Ro antibodies. METHODS: Between March 2014 and September 2020, 52 pregnant women with anti-SSA antibodies were enrolled. No bradyarrhythmia was observed in the group. A pulsed Doppler examination of the fetal heart was performed to obtain measurements of the mechanical Doppler AV interval. Doppler measurements were performed using four methods: LV in/out, PV/PA, InnV/AA, and SVC/AA. A statistical analysis was performed to examine the mean, standard deviation, significant difference, and correlation of the four methods. The detection rate of each method was also calculated. RESULTS: There was no significant difference in the AV intervals between any of the four methods. There was also a positive correlation in the AV intervals of each of the four methods. The fetal heart rate and AV interval showed no correlation. The gestational age and AV interval also showed no correlation. The detection rate was highest for LV in/out (62.6%, 95% confidence interval: 56.5-68.4). CONCLUSION: All four pulsed Doppler methods are useful for measuring AV intervals. The most practical method is LV in/out.
- Masaya Yamoto; Kouji Nagata; Keita Terui; Masahiro Hayakawa; Hiroomi Okuyama; Shoichiro Amari; Akiko Yokoi; Kouji Masumoto; Tadaharu Okazaki; Noboru Inamura; Katsuaki Toyoshima; Yuhki Koike; Yuta Yazaki; Taizo Furukawa; Noriaki UsuiChildren (Basel, Switzerland) 9 6 2022年06月BACKGROUND: Treatment modalities for neonates with congenital diaphragmatic hernia (CDH) have greatly improved in recent years, with a concomitant increase in survival. However, long-term outcomes restrict the identification of optimal care pathways for CDH survivors in adolescence and adulthood. Therefore, we evaluated the long-term outcomes within the Japanese CDH Study Group (JCDHSG). METHODS: Participants were born with CDH between 2006 and 2018 according to the JCDHSG. Participants were enrolled in the database at 1.5, 3, 6, and 12 years old. Follow-up items included long-term complications, operations for long-term complication, and home medical care. RESULTS: A total of 747 patients were included in this study, with 626 survivors (83.8%) and 121 non-survivors (16.2%). At 1.5, 3, 6, and 12 years old, 45.4%, 36.5%, 34.8%, and 43.6% developed complications, and 20.1%, 14.7%, 11.5%, and 5.1% of participants required home care, respectively. Recurrence, pneumonia, pneumothorax, gastroesophageal reflux disease, and intestinal obstruction decreased with age, and thoracic deformity increased with age. CONCLUSIONS: As CDH survival rates improve, there is a need for continued research and fine-tuning of long-term care to optimize appropriate surveillance and long-term follow-up.
- 先天性横隔膜ヘルニアに対する重症度予測指標の検討 システマティックレビュー正畠 和典; 矢本 真也; 梅田 聡; 藤井 誠; 白石 真之; 永田 公二; 照井 慶太; 早川 昌弘; 甘利 昭一郎; 増本 幸二; 岡崎 任晴; 稲村 昇; 漆原 直人; 豊島 勝昭; 内田 恵一; 古川 泰三; 岡和田 学; 横井 暁子; 田附 裕子; 奥山 宏臣; 臼井 規朗日本小児外科学会雑誌 58 3 536 - 536 (一社)日本小児外科学会 2022年04月
- Tomohiko Tanaka; Noboru Inamura; Yukiko Kawazu; Futoshi KayataniJournal of Fetal Medicine 2022年03月
- Noboru Inamura; Jun Narita; Futoshi KayataniPediatrics international : official journal of the Japan Pediatric Society 64 1 e15216 2022年01月
- Nobuyoshi Kusano; Satoshi Marutani; Hideki Masumi; Kazushi Ueshima; Nori Takada; Takako Nishino; Osamu Maenishi; Keisuke Sugimoto; Noboru InamuraThe Annals of Thoracic Surgery 2021年12月We report the case of a 4-year-old boy with coarctation of the aorta resulting from persistent fifth aortic arch, a rare abnormality, along with an interrupted fourth aortic arch. When he visited a general practitioner with an upper respiratory infection, a heart murmur was noted. Computed tomography findings led to the diagnosis of persistent fifth aortic arch with an interrupted fourth aortic arch. He underwent aortic arch repair, excision of the fifth aortic arch, and anastomosis of the original arch with the descending aorta. Pathologically, the tissue of the fifth aortic arch was different from that of the normal aortic arch.
- Keita Terui; Taizo Furukawa; Kouji Nagata; Masahiro Hayakawa; Hiroomi Okuyama; Shoichiro Amari; Akiko Yokoi; Kouji Masumoto; Masaya Yamoto; Tadaharu Okazaki; Noboru Inamura; Katsuaki Toyoshima; Keiichi Uchida; Manabu Okawada; Yasunori Sato; Noriaki UsuiPediatric surgery international 37 12 1667 - 1673 2021年09月PURPOSE: Predicting lethal pulmonary hypoplasia in infants with congenital diaphragmatic hernia (CDH) before extracorporeal membrane oxygenation (ECMO) initiation is difficult. This study aimed to predict lethal pulmonary hypoplasia in patients with CDH prior to ECMO. METHODS: This was a multicenter cohort study involving neonates prenatally diagnosed with isolated unilateral CDH (born 2006-2020). Patients who required ECMO due to respiratory insufficiency were included in this study. Patients who underwent ECMO due to transient disorders were excluded from analysis. Blood gas analysis data within 24 h of birth were compared between survivors and non-survivors. Predictive abilities were assessed for factors with significant differences. RESULTS: Overall, 34 patients were included (18 survivors and 16 non-survivors). The best pre-ductal PaO2 was significantly lower in non-survivors than in survivors (50.4 [IQR 30.3-64.5] vs. 67.5 [IQR 52.4-103.2] mmHg, respectively; p = 0.047). A cutoff PaO2 of 42.9 mmHg had a sensitivity, specificity, and positive predictive value of 50.0%, 94.4%, and 88.9%, respectively, to predict mortality. CONCLUSION: The best PaO2 within 24 h after birth predicted mortality following ECMO initiation. This should be shared to families and caregivers to optimize the best interests of the infants with CDH.
- Noboru Inamura; Nori Takada; Satoshi MarutaniJournal of clinical ultrasound : JCU 50 1 86 - 89 2021年06月Absent pulmonary valve syndrome (APVS) with tricuspid atresia is very rare. We report a case of APVS in which the fetus died due to severe hydrops fetalis. In addition to weakened cardiac contraction due to left ventricular noncompaction cardiomyopathy, a circular shunt through a ventricular septal defect exacerbated heart failure. Although APVS with tricuspid valve atresia is not supposed to cause a circular shunt, we herein present the echocardiographic demonstration of a case of circular shunt.
- Masaya Yamoto; Satoko Ohfuji; Naoto Urushihara; Keita Terui; Kouji Nagata; Tomoaki Taguchi; Masahiro Hayakawa; Shoichiro Amari; Kouji Masumoto; Tadaharu Okazaki; Noboru Inamura; Katsuaki Toyoshima; Keiichi Uchida; Taizo Furukawa; Manabu Okawada; Akiko Yokoi; Yukata Kanamori; Noriaki Usui; Yuko Tazuke; Ryuta Saka; Hiroomi OkuyamaSurgery today 51 6 880 - 890 2021年06月PURPOSE: To date, there is no compelling evidence of the optimal timing of surgery for congenital diaphragmatic hernia (CDH). This study aimed to establish the optimal timing of surgery in neonates with isolated left-sided CDH. METHODS: This multicenter cohort study enrolled 276 patients with isolated left-sided CDH at 15 institutions. Based on the timing of surgery, the patients were classified into four groups [< 24 h (G1), 24-47 h (G2), 48-71 h (G3), and ≥ 72 h (G4)]. The clinical outcomes were compared among the groups using a logistic regression model, after adjusting for potential confounders, such as disease severity. RESULTS: Multivariate analyses showed that G2 also had a lower mortality rate than the other groups. In mild and severe cases, there were no significant differences in mortality across the four groups. In moderate cases, G2 resulted in significantly increased survival rates, compared with G1. CONCLUSION: The study results suggest that surgery within 24 h of birth is not recommended for patients with moderate severity CDH, that there is no benefit in the delay of surgery for more than 72 h in mild severity CDH patients, and that there is no definite optimal time to perform surgery in severe cases of CDH.
- Noboru Inamura; Takeshi Taniguchi; Nori TakadaEchocardiography (Mount Kisco, N.Y.) 38 6 1081 - 1083 2021年06月We diagnosed two cases of double aortic arch (DAA) remotely. In both cases, the right aortic arch was suspected, and a remote diagnosis was requested. We performed a remote diagnosis by the spatio-temporal image correlation (STIC) method. DAA was diagnosed by detecting the left aortic arch in an axial transverse section in the three-vessel trachea view. Since the STIC method can make multiple cross sections, making a diagnosis by the STIC method was useful for the remote diagnosis of these patients. In particular, HD flow render mode clearly showed left aortic arch, so it was possible to diagnose DAA.
- Manabu Okawada; Satoko Ohfuji; Masaya Yamoto; Naoto Urushihara; Keita Terui; Kouji Nagata; Tomoaki Taguchi; Masahiro Hayakawa; Shoichirou Amari; Kouji Masumoto; Tadaharu Okazaki; Noboru Inamura; Katsuaki Toyoshima; Mikihiro Inoue; Taizo Furukawa; Akiko Yokoi; Yutaka Kanamori; Noriaki Usui; Yuko Tazuke; Ryuta Saka; Hiroomi OkuyamaSurgery today 51 10 1694 - 1702 2021年04月PURPOSE: We compared the efficacy of thoracoscopic repair (TR) with that of open repair (OR) for neonatal congenital diaphragmatic hernia (CDH). METHODS: The subjects of this multicenter retrospective cohort study were 524 infants with left-sided isolated CDH, diagnosed prenatally, and treated at one of 15 participating hospitals in Japan between 2006 and 2018. The outcomes of infants who underwent TR and those who underwent OR were compared, applying propensity score matching. RESULTS: During the study period, 57 infants underwent TR and 467 underwent OR. Ten of the infants who underwent TR required conversion to OR for technical difficulties and these patients were excluded from the analysis. The survival rate at 180 days was similar in both groups (TR 98%; OR 93%). Recurrence developed after TR in 3 patients and after OR in 15 patients (TR 7%, OR 3%, p = 0.40). The propensity score was calculated using the following factors related to relevance of the surgical procedure: prematurity (p = 0.1), liver up (p < 0.01), stomach position (p < 0.01), and RL shunt (p = 0.045). After propensity score matching, the multivariate analysis adjusted for severity classification and age at surgical treatment revealed a significantly shorter hospital stay (odds ratio 0.50) and a lower incidence of chronic lung disease (odds ratio 0.39) in the TR group than in the OR group. CONCLUSIONS: TR can be performed safely for selected CDH neonates with potentially better outcomes than OR.
- Makiko Fuyuki; Noriaki Usui; Tomoaki Taguchi; Masahiro Hayakawa; Kouji Masumoto; Yutaka Kanamori; Shoichiro Amari; Masaya Yamoto; Naoto Urushihara; Noboru Inamura; Akiko Yokoi; Manabu Okawada; Tadaharu Okazaki; Katsuaki Toyoshima; Taizou Furukawa; Keita Terui; Satoko Ohfuji; Yuko Tazuke; Keiichi Uchida; Hiroomi OkuyamaJournal of perinatology : official journal of the California Perinatal Association 41 4 814 - 823 2021年04月OBJECTIVE: To determine the appropriate initial ventilatory mode for neonatal congenital diaphragmatic hernia (CDH) by comparing patient prognosis following conventional mechanical ventilation (CMV) versus high-frequency oscillatory ventilation (HFO). STUDY DESIGN: This multicenter retrospective cohort study was performed at 15 participating hospitals in Japan between 2011 and 2016. The 328 eligible CDH infants were classified into CMV (n = 78) and HFO groups (n = 250) to compare mortality and incidence of bronchopulmonary dysplasia (BPD). Propensity score matching was applied to reduce confounding by indication. RESULT: While crude mortality was significantly higher in the HFO than the CMV group, adjusted odds ratio (OR) did not show significant difference in mortality between groups (OR of HFO group: 0.98, 95% confidence interval (CI): 0.57-1.67). Adjusted OR of BPD incidence showed no significant difference between groups (OR of HFO group: 1.66, 95%CI: 0.50-5.49). CONCLUSION: Initial ventilatory mode in CDH patients, whether CMV or HFO, does not affect prognosis.
- 胎児診断により動脈管閉鎖に伴う血行動態変化を観察できた左腕頭動脈孤立症の1例前田 崇彰; 加地 剛; 早渕 康信; 中川 竜二; 祖川 英至; 吉田 あつ子; 米谷 直人; 須賀 健一; 稲村 昇; 苛原 稔超音波医学 47 Suppl. S419 - S419 (公社)日本超音波医学会 2020年11月
- Right Ventricular Outflow Obstruction by a Membranous Septal Aneurysm in a Ventricular Septal DefectYuhei Yamashita; Satoshi Marutani; Kosuke Nishi; Kazushi Ueshima; Nori Takata; Takako Nishino; Keisuke Sugimoto; Noboru InamuraPediatric Cardiology and Cardiac Surgery 36 3 252 - 255 2020年10月
- Noboru Inamura; Takeshi Taniguchi; Tatsumi Yamada; Tomohiko Tanaka; Ken Watanabe; Ken Kumagaya; Yoichiro Ishii; Tsubura Ishii; George Hayashi; Nobuko Shiono; Tomoaki IkedaPediatric cardiology 41 5 979 - 984 2020年06月 [査読有り]
We prospectively performed remote fetal cardiac screening using the spatio-temporal image correlation (STIC), and examined the usefulness and problems of remote screening. We performed heart screening for all pregnant women at four obstetrics clinics over the three years from 2009 to 2014. The STIC data from 15,404 examinations in normal pregnancies (16-27 weeks, median 25 weeks) were analyzed. Obstetricians and sonographer collected STIC data from four-chamber view images. Eight pediatric cardiologists analyzed the images offline. A normal heart was diagnosed in 14,002 cases (90.9%), an abnormal heart was diagnosed in 457 cases (3.0%), and poor images were obtained in 945 cases (6.1%). 138 cases had congenital heart disease (CHD) after birth, and severe CHD necessitating hospitalization occurred in 36 cases. We were not able to detect CHD by screening in 12 cases. The sensitivity and specificity of STIC in CHD screening was 50% and 99.5%, respectively. The sensitivity and specificity of STIC in screening for severe CHD was 82% and 99.9%, respectively. The STIC method was useful in fetal remote screening for CHD. However, the fact that > 10% of images that could not be analyzed by this method was a problem. - Kazunori Masahata; Noriaki Usui; Kouji Nagata; Keita Terui; Masahiro Hayakawa; Shoichiro Amari; Kouji Masumoto; Tadaharu Okazaki; Noboru Inamura; Naoto Urushihara; Katsuaki Toyoshima; Keiichi Uchida; Taizo Furukawa; Manabu Okawada; Akiko Yokoi; Hiroomi Okuyama; Tomoaki TaguchiPediatric surgery international 36 6 669 - 677 2020年06月 [査読有り]
PURPOSE: This study aimed to elucidate the clinical characteristics of neonates with congenital diaphragmatic hernia (CDH) associated with pneumothorax and evaluate the risk factors for the development of pneumothorax. METHODS: A retrospective cohort study was conducted in the 15 institutions participating in the Japanese CDH Study Group. A total of 495 neonates with isolated CDH who were born between 2011 and 2018 were analyzed in this study. RESULTS: Among the 495 neonates with isolated CDH, 52 (10.5%) developed pneumothorax. Eighteen (34.6%) patients developed pneumothorax before surgery, while 34 (65.4%) developed pneumothorax after surgery. The log-rank test showed that the cumulative survival rate was significantly lower in patients with pneumothorax than in those without pneumothorax. Univariate analysis revealed significant differences between patients with pneumothorax and those without pneumothorax with regard to the best oxygenation index within 24 h after birth, mean airway pressure (MAP) higher than 16 cmH2O, diaphragmatic defect size, and need for patch closure. Multiple logistic regression analysis indicated that only the MAP was associated with an increased risk of pneumothorax. CONCLUSIONS: The cumulative survival rate was significantly lower in isolated CDH patients with pneumothorax than in those without pneumothorax. A higher MAP was a risk factor for pneumothorax in CDH patients. - Noboru InamuraCASE (Philadelphia, Pa.) 4 2 57 - 58 2020年04月 [査読有り]
- N. Inamura; R. K. PoohUltrasound in Obstetrics & Gynecology 55 2 282 - 283 2020年02月 [査読有り]
- Keita Terui; Kouji Nagata; Masahiro Hayakawa; Hiroomi Okuyama; Shoichirou Amari; Akiko Yokoi; Kouji Masumoto; Naoto Urushihara; Tadaharu Okazaki; Noboru Inamura; Katsuaki Toyoshima; Keiichi Uchida; Taizo Furukawa; Manabu Okawada; Yasunori Sato; Noriaki UsuiEuropean journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie 30 1 51 - 58 2019年10月 [査読有り]
INTRODUCTION: We aimed to establish and validate a risk score for fetuses with congenital diaphragmatic hernia (CDH) using only prenatal ultrasound findings. MATERIAL AND METHODS: Derivation (2011-2016, n = 350) and validation (2006-2010, n = 270) cohorts were obtained from a Japanese CDH study group database. Using a logistic regression analysis, we created a prediction model and weighted scoring system from the derivation dataset and calculated the odds ratio of an unsatisfactory prognosis (death within 90 days of life or hospitalization duration exceeding 180 days). Five adverse prognostic factors obtained using prenatal ultrasound, including an observed/expected lung area-to-head circumference ratio (o/eLHR) <25%, liver herniation occupying more than one-third of the thoracic space, thoracic stomach, right-side CDH, and severe malformations, were used as predictors. The obtained model was validated using the validation cohort. RESULTS: The unsatisfactory prognosis prediction model was obtained based on the adjusted odds ratios. The C statistics of the model were 0.83 and 0.80 in the derivation and validation datasets, respectively. The five variables were weighted proportionally to their adjusted odds ratios for an unsatisfactory prognosis (o/eLHR <25%, 1 point; liver herniation occupying more than one-third of the thoracic space, 1 point; thoracic stomach, 1 point; right-side CDH, 2 points; and severe malformations, 3 points). Unsatisfactory prognosis rates for the low- (0-2 points), intermediate- (3-5 points), and high-risk (6-8 points) groups were 17, 46, and 100%, respectively (p < 0.001), in the validation cohort. CONCLUSION: Our simple risk score effectively predicted the prognosis of fetuses with CDH. - 前田 崇彰; 加地 剛; 早渕 康信; 中川 竜二; 祖川 英至; 吉田 あつ子; 米谷 直人; 須賀 健一; 稲村 昇; 苛原 稔現代産婦人科 68 Suppl. S43 - S43 中国四国産科婦人科学会 2019年09月
- Miyoshi T; Maeno Y; Hamasaki T; Inamura N; Yasukochi S; Kawataki M; Horigome H; Yoda H; Taketazu M; Nii M; Hagiwara A; Kato H; Shimizu W; Shiraishi I; Sakaguchi H; Ueda K; Katsuragi S; Yamamoto H; Sago H; Ikeda T; Japan Fetal Arrhythmia GroupJournal of the American College of Cardiology 74 7 874 - 885 2019年08月 [査読有り]
- 岡田 満; 和田 紀久; 坂田 尚己; 稲村 昇; 鈴木 彩子; 八木 誠; 佐々木 隆士; 近藤 宏樹医学教育 50 Suppl. 117 - 117 (一社)日本医学教育学会 2019年07月 [査読有り]
- Morimoto Y; Inamura N; Takemura TAJP reports 9 3 e235 - e237 2019年07月 [査読有り]
Transposition of the great arteries type I is a severe congenital heart disease that induces serious cyanosis immediately after birth and death within 24 hours, unless proper treatment is administered. A few cases have presented with reversed differential cyanosis, manifesting as separated cyanosis with high SpO 2 values in the lower limbs. However, there have been few reports of survivors of transposition of the great arteries type I presenting with reversed differential cyanosis. We experienced a case of transposition of the great arteries type I presenting with reversed differential cyanosis immediately after birth. The infant was urgently transported because of postnatal SpO 2 of 40% in the upper limbs and 90% in the lower limbs. The echocardiographic diagnosis was transposition of the great arteries type I with a narrow foramen ovale. We immediately performed balloon atrioseptostomy, and the reversed differential cyanosis was improved. The infant seems to have presented with reversed differential cyanosis because of the foramen ovale narrowing and complicating pulmonary hypertension due to fetal circulation and characteristic of transposition of the great arteries type I. Congenital heart disease, presenting with reversed differential cyanosis, is a clinical condition requiring emergency management. - 胎児診断により出生直後の左腕頭動脈肺動脈起始から左腕頭動脈孤立症への経過を観察できた1例加地 剛; 早渕 康信; 中川 竜二; 稲村 昇; 苛原 稔日本小児循環器学会雑誌 35 Suppl.1 s1 - 394 (NPO)日本小児循環器学会 2019年06月
- 胎児頻脈性不整脈に対する経胎盤的抗不整脈薬投与に関する臨床試験 多施設共同試験三好 剛一; 稲村 昇; 安河内 聰; 堀米 仁志; 与田 仁志; 竹田津 未生; 新居 正基; 左合 治彦; 前野 泰樹; 池田 智明; 日本胎児不整脈班超音波医学 46 Suppl. S712 - S712 (公社)日本超音波医学会 2019年04月
- Torigoe F; Ishida H; Ishii Y; Ishii R; Narita J; Kawazu Y; Kayatani F; Inamura NUltrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2019年04月 [査読有り]
- Kawazu Y; Inamura N; Kayatani F; Taniguchi TPrenatal diagnosis 39 3 195 - 199 2019年02月 [査読有り]
- 照井 慶太; 永田 公二; 早川 昌弘; 奥山 宏臣; 甘利 昭一郎; 増本 幸二; 漆原 直人; 岡崎 任晴; 稲村 昇; 豊島 勝昭; 内田 恵一; 古川 泰三; 岡和田 学; 佐藤 泰憲; 田口 智章; 臼井 規朗; 日本先天性横隔膜ヘルニアスタディグループ日本周産期・新生児医学会雑誌 54 別冊 14 - 15 (一社)日本周産期・新生児医学会 2019年01月
- Keiko Ueda; Yasuki Maeno; Takekazu Miyoshi; Noboru Inamura; Motoyoshi Kawataki; Mio Taketazu; Masaki Nii; Akiko Hagiwara; Hitoshi Horigome; Makio Shozu; Wataru Shimizu; Satoshi Yasukochi; Hitoshi Yoda; Isao Shiraishi; Heima Sakaguchi; Shinji Katsuragi; Haruhiko Sago; Tomoaki Ikeda; on behalf of Japan Fetal Arrhythmia GroupJournal of Maternal-Fetal and Neonatal Medicine 31 19 2605 - 2610 2018年10月 [査読有り]
Objectives: To investigate the clinical course of fetal tachycardia and analyze the impact of intrauterine treatment on the postnatal treatment and patient outcomes. Study design: This was a retrospective review of cases of fetal tachycardia that occurred from 2004 to 2006. Data were collected from questionnaires that were sent to all 750 secondary or tertiary perinatal care centers in Japan. Results: Eighty-two cases (14 with fetal hydrops) were analyzed (supraventricular tachycardia [SVT], n = 52 atrial flutter [AFL], n = 23 and ventricular tachycardia, n = 7). The overall mortality was 3.7%. Intrauterine treatment was performed for 41 fetuses (50.0%). Digoxin, flecainide and sotalol were mainly used for SVT and AFL. Fetal tachycardia resolved in 90.0% (27/30) of the cases without fetal hydrops and 90.9% (10/11) of the cases with fetal hydrops. Intrauterine treatment significantly reduced the incidence of cesarean delivery (29.3 vs. 70.7%, p < .01), preterm birth (12.2 vs. 41.5%, p =.02) and neonatal arrhythmias (48.8 vs. 78.0%, p =.01) in comparison to untreated fetuses. Conclusions: This nationwide survey revealed that intrauterine treatment was performed for approximately half of the cases of fetal tachycardia and was associated with lower rates of cesarean delivery, premature birth and neonatal arrhythmias in comparison to untreated fetuses. - Toshiyuki Hata; Megumi Ito; Emiko Nitta; Ritsuko Pooh; Jun Sasahara; Noboru InamuraJournal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine 37 10 2465 - 2467 2018年10月 [査読有り]
- 胎児治療最前線:薬物治療/カテーテル治療 胎児頻脈性不整脈に対する経胎盤的抗不整脈薬投与に関する臨床試験 多施設共同前向き介入試験三好 剛一; 前野 泰樹; 左合 治彦; 稲村 昇; 安河内 聰; 堀米 仁志; 与田 仁志; 竹田津 未生; 新居 正基; 白石 公; 池田 智明; 日本胎児不整脈班日本小児循環器学会雑誌 34 Suppl.1 s1 - 146 (NPO)日本小児循環器学会 2018年07月
- Hiroshi Kawamura; Noboru Inamura; Yuka Inoue; Yukiko Kawazu; Futoshi Kayatani; Nobuaki MitsudaJournal of Medical Ultrasonics 45 3 431 - 435 2018年07月 [査読有り]
Purpose: To validate the relationship between retrograde blood flow in the aortic isthmus (AoI-R) by color Doppler in fetal echocardiography and postnatal coarctation of the aorta (CoA) diagnosed as isthmus narrowing. Methods: This was a retrospective study of 22 cases of prenatally suspected simple CoA or CoA with small ventricular septum defect based on fetal echocardiography performed by pediatric cardiologists in our hospital. Gestational age at the first detection of AoI-R and the optimal cut-off value for the prediction of postnatal CoA were mainly evaluated according to the postnatal diagnosis of CoA. Results: All 22 cases had AoI-R prenatally, and nine of them (40.9%) had isthmus narrowing and were diagnosed as having CoA immediately after birth. The gestational age at the first detection of AoI-R was significantly lower in cases with postnatal CoA than in those without (average 34.4 weeks P = 0.034). The cut-off value for the prediction of postnatal CoA was 35.5 weeks of gestation, with a sensitivity and specificity of 77.8 and 69.2%, respectively. Conclusion: AoI-R determined by color Doppler echocardiography can become a useful tool in the screening of fetal CoA, especially at < 35 weeks of gestation. - Emi M; Inamura NAJP reports 8 3 e174 - e179 2018年07月 [査読有り]
- 三好 剛一; 前野 泰樹; 左合 治彦; 稲村 昇; 川滝 元良; 堀米 仁志; 与田 仁志; 竹田津 未生; 生水 真紀夫; 萩原 聡子; 白石 公; 上田 恵子; 桂木 真司; 池田 智明; 日本胎児不整脈班日本周産期・新生児医学会雑誌 54 2 595 - 595 (一社)日本周産期・新生児医学会 2018年06月
- HDlive Flow Silhouette Mode for Diagnosis of Ectopia Cordis With a Left Ventricular Diverticulum at 15 Weeks' GestationHata T; Ito M; Nitta E; Pooh R; Sasahara J; Inamura NJ Ultrasound Med 2018年03月 [査読有り]
- Yasuhiro Hirano; Noboru Inamura; Yukiko Kawazu; Hisaaki Aoki; Futoshi Kayatani; Shigemitsu Iwai; Hiroaki KawataWorld journal for pediatric & congenital heart surgery 9 1 54 - 59 2018年01月 [査読有り]
BACKGROUND: At our institution, we perform bilateral pulmonary artery banding (BPAB) as the first-stage palliation for interrupted aortic arch (IAA) with low birth weight or severe subaortic stenosis (SAS). The present study aimed to identify factors that may influence the decision regarding the type of second-stage operation, that is, univentricular palliation or biventricular repair, in these patients. METHODS: Cardiac catheterization and angiographic data of nine patients with IAA who underwent initial BPAB and subsequent univentricular or biventricular repair were retrospectively analyzed. RESULTS: Between 2004 and 2014, of nine patients with IAA who underwent initial BPAB, biventricular repair was subsequently performed in six patients (group B) and univentricular repair in three patients (group U). All patients survived. There was no significant intergroup difference in IAA classification, location of ventricular septal defect, presence of 22q11.2 deletion, presence of aberrant right subclavian artery, band diameter, or post-BPAB pulmonary artery pressure and index. Timing of BPAB and the body weight at the time of BPAB, however, differed significantly between the groups ( P = .02). Catheter data before BPAB were not significantly different between the groups, with the exception of the degree of subaortic stenosis (or hypoplasia of the left ventricular outflow tract) expressed as percentage of the normal end-systolic aortic valve annular diameter for patient body surface area. This metric (%SAS before BPAB) was significantly higher in group B (60%-68%) than in group U (47%-60%; P = .04). Among patients for whom baseline %SAS was < 60%, the %SAS did not increase after BPAB. CONCLUSION: The most important factor that allowed biventricular repair was not the pulmonary artery pressure or diameter but the degree of SAS. Patients who initially had more severe SAS ultimately underwent univentricular repair due to lack of substantial improvement in dimensions of the left ventricular outflow tract after BPAB. - Hisaaki Aoki; Misugi Emi; Noboru Inamura; Shigemitsu Iwai; Futoshi KayataniJournal of Arrhythmia 33 6 649 - 651 2017年12月 [査読有り]
Cardiac resychronization therapy (CRT) was performed via transvenous approach in a 2-year-old boy with a tetralogy of Fallot and postoperative severe heart failure, and complete atrioventricular block treated with a dual-chamber pacemaker. Epicardial leads were unavailable because of mediastinitis and the presence of severe bilateral pleural effusions requiring continuous drainage. There were no procedural complications. Biventricular pacing was significantly effective and both mediastinitis and pleural effusions recurred. The transvenous CRT was exchanged for an epicardial CRT after 4 months because of the possibility of a venous obstruction. - Kawamura H; Inamura N; Inoue Y; Kawazu Y; Kayatani F; Mitsuda NJ Med Ultrason (2001) 45 3 431 - 435 2017年11月 [査読有り]
胎児心エコーにおけるカラーDoppler法で観察される大動脈峡部の逆行性血流が、大動脈縮窄症の指標となるか検討した。当院で胎児心エコー検査におけるカラーDoppler法により、3-vessel tracheal view(3VTV)で逆行性血流を有し、単純型大動脈縮窄症もしくは心室中隔欠損合併で大動脈縮窄症疑いであった22例を対象患児とし、後向きに評価した。その結果、出生直後の検査で大動脈縮窄症と診断された患児は9例(40.9%)に認められ、大動脈縮窄群では、逆行性血流が最初に検出された胎齢が非縮窄群よりも有意に早期であり、ROC曲線から、逆行性血流が最初に検出された胎齢が、出生後大動脈縮窄症と関連することが明らかにされた。また、出生後の大動脈縮窄推定に関するカットオフ値は胎齢35.5週で、感度77.8%、特異度69.2%、PPV 63.6%、NPV 81.8%、正確度72.7%であったことから、特に在胎35週未満の場合には、カラーDoppler法により、逆行性血流を評価することは大動脈縮窄症の出生前スクリーニングとして有用と判断された。 - Kosuke Nishi; Noboru Inamura; Satoshi Marutani; Takako Nishino; Tsukasa TakemuraPEDIATRICS INTERNATIONAL 59 10 1091 - 1093 2017年10月 [査読有り]
- Takekazu Miyoshi; Yasuki Maeno; Haruhiko Sago; Noboru Inamura; Satoshi Yasukochi; Motoyoshi Kawataki; Hitoshi Horigome; Hitoshi Yoda; Mio Taketazu; Makio Shozu; Masaki Nii; Akiko Hagiwara; Hitoshi Kato; Wataru Shimizu; Lsao Shiraishi; Heima Sakaguchi; Keiko Ueda; Shinji Katsuragi; Tomoaki Ikeda; Haruko Yamamoto; Toshimitsu HamasakiBMJ OPEN 7 8 e016597 2017年08月 [査読有り]
Introduction Several retrospective or single-centre studies demonstrated the efficacy of transplacental treatment of fetal tachyarrhythmias. Our retrospective nationwide survey showed that the fetal therapy will be successful at an overall rate of 90%. For fetuses with hydrops, the treatment success rate will be 80%. However, standard protocol has not been established. The objective of this study is to evaluate the efficacy and safety of the protocol-defined transplacental treatment of fetal tachyarrhythmias. Participant recruitment began in October 2010. Methods and analysis The current study is a multicentre, single-arm interventional study. A total of 50 fetuses will be enrolled from 15 Japanese institutions. The protocol-defined transplacental treatment is performed for singletons with sustained fetal tachyarrhythmia >= 180 bpm, with a diagnosis of supraventricular tachycardia or atrial flutter. Digoxin, sotalol, flecainide or a combination is used for transplacental treatment. The primary endpoint is disappearance of fetal tachyarrhythmias. The secondary endpoints are fetal death related to tachyarrhythmia, proportion of preterm birth, rate of caesarean section attributable to fetal arrhythmia, improvement in fetal hydrops, neonatal arrhythmia, neonatal central nervous system disorders and neonatal survival. Maternal, fetal and neonatal adverse events are evaluated at 1 month after birth. Growth and development are also evaluated at 18 and 36 months of corrected age. Ethics and dissemination The Institutional Review Board of the National Cerebral and Cardiovascular Center of Japan has approved this study. Our findings will be widely disseminated through conference presentations and peerreviewed publications. - 豊川 富子; 稲村 昇; 萱谷 太; 河津 由紀子; 濱道 裕二; 岡本 伸彦日本小児科学会雑誌 121 8 1333 - 1337 (公社)日本小児科学会 2017年08月歌舞伎症候群37例のうち心疾患を合併した18例(男10例、女8例)を、大動脈狭窄などの左室閉塞性疾患(LOL+)12例とそれ以外の心疾患(LOL-)6例に分けて、後方視的に検討した。初診時年齢はLOL-の1例を除き全例生後0日であり、LOL+のうち7例は出生前に心疾患が診断されていた。合併症は、全例に発達遅滞を認め、口腔外科疾患83.3%、腎疾患61.1%、消化器疾患55.5%、てんかん5.5%であった。LOL+の合併症はLOL-と比較して消化器疾患が多かった。心臓手術はLOL-の6例中1例、LOL+の12例中9例で行われた。死亡例は両群に1例ずつ認め、いずれも感染症が契機であった。
- Terui K; Nagata K; Kanamori Y; Takahashi S; Hayakawa M; Okuyama H; Inamura N; Yoshida H; Taguchi T; Usui NJ Perinatol 37 7 805 - 808 2017年07月 [査読有り]
OBJECTIVE: To establish a simple risk stratification system for patients with congenital diaphragmatic hernia (CDH) based on postnatal information within 24 h after birth. STUDY DESIGN: A multi-institutional retrospective cohort study was conducted including 348 neonates who had isolated CDH born between 2006 and 2010. Based on the two most powerful variables for 90-day survival selected by multivariate analyses, a risk stratification system was established. RESULTS: Multiple logistic regression analysis identified two adverse prognostic factors: an Apgar score at 1 min (Ap1) of 0-4 (odds ratio (OR) 3.3, P = 0.004), and a best oxygenation index (OI) >= 8.0 (OR 11.4, P < 0.001). Based on a combinations of these two factors, patients were classified into three risk categories. The 90-day survival rates in categories 1-3 were 100, 88 and 52%, respectively (P < 0.001). CONCLUSION: Our simple risk stratification system based on Ap1 and best OI was capable of predicting mortality well. - The impact of intrauterine treatment on fetal tachycardia: a nationwide survey in JapanUeda K; Maeno Y; Miyoshi T; Inamura N; Kawataki M; Taketazu M; Nii M; Hagiwara A; Horigome H; Shozu M; Shimizu W; Yasukochi S; Yoda H; Shiraishi I; Sakaguchi H; Katsuragi S; Sago H; Ikeda TJ Matern Fetal Neonatal Med 19 1 - 6 2017年07月 [査読有り]
- Hidekazu Ishida; Yukiko Kawazu; Futoshi Kayatani; Noboru InamuraCARDIOLOGY IN THE YOUNG 27 4 634 - 638 2017年05月 [査読有り]
Background: A number of case reports show various outcomes of premature closure of the ductus arteriosus in utero, including persistent pulmonary hypertension of the newborn and fetal or neonatal death; however, no study clarifies the clinical observations that are related to their prognoses. We aimed to clarify the prognostic factors of intrauterine ductal closure by a systematic literature review. Data sources We searched PubMed database (1975-2014) to identify case reports and studies on intrauterine closure of the ductus arteriosus, including maternal, fetal, and neonatal clinical information and their prognoses. Results: We analysed the data of 116 patients from 39 articles. Of these, 12 (10.3%) died after birth or in utero. Fetal or neonatal death was significantly correlated with fetal hydrops (odds ratio = 39.6, 95% confidence interval = 4.6-47.8) and complete closure of the ductus arteriosus (odds ratio = 5.5, 95% confidence interval = 1.2-15.1). Persistent pulmonary hypertension was observed in 33 cases (28.4%), and was also correlated with fetal hydrops (odds ratio = 4.2, 95% confidence interval = 1.3-4.6) and complete closure of the ductus arteriosus (odds ratio = 5.5, 95% confidence interval = 1.6-6.0). Interestingly, maternal drug administration was not correlated with the risk of death and persistent pulmonary hypertension. Conclusions: Fetal hydrops and complete ductal closure are significant risk factors for both death and persistent pulmonary hypertension. Cardiac or neurological prognoses could be favourable if the patients overcome right heart failure during the perinatal period. - T. Hattori; M. Hayakawa; M. Ito; Y. Sato; K. Tamakoshi; Y. Kanamorit; H. Okuyama; N. Inannura; S. Takahashi; Y. Fujino; T. Taguchi; N. UsuiJOURNAL OF PERINATOLOGY 37 3 265 - 269 2017年03月 [査読有り]
OBJECTIVE: To seek a simple approach for prenatally classifying congenital diaphragmatic hernia (CDH) severity using fetal magnetic resonance imaging (MRI) markers. STUDY DESIGN: A retrospective, multicenter study using questionnaires to investigate fetal MRI findings. We included fetuses prenatally diagnosed with isolated left-sided CDH and delivered after 36 weeks of gestation. We focused on three fetal MRI morphological signs: incomplete pulmonary baseline (IPB), liver up (LU) and retrocardiac stomach (RCS). We also evaluated the fetal MRI score defined as the total number of positive signs; the primary outcome was survival at discharge. RESULTS: In 256 patients (from 56 institutions), IPB, LU and RCS findings correlated with lower survival: odds ratio (95% confidence interval), 0.16 (0.08 to 0.33); 0.24 (0.12 to 0.51); and 0.14 (0.07 to 0.28); respectively. Patients with higher fetal MRI scores had a higher mortality rate. CONCLUSION: IPB, LU and RCS on fetal MRI are related to CDH severity. - 平野 恭悠; 稲村 昇; 河津 由紀子; 江見 美杉; 豊川 富子; 松尾 久実代; 田中 智彦; 青木 寿明; 高橋 邦彦; 笹原 淳; 橘 一也; 竹内 宗之; 吉田 佳織; 盤井 成光; 萱谷 太大阪府立母子保健総合医療センター雑誌 32 1-2 9 - 13 (地独)大阪府立病院機構大阪母子医療センター 2017年03月症例は在胎25週に胎児水腫と心拡大を指摘され、当院へ紹介された。胎児心エコー検査で重症大動脈弁狭窄症(critical aortic stenosis:cAS)と診断した。左室機能は極度に低下し、重度の僧帽弁逆流と卵円孔の狭小化を認めた。胎児死亡の可能性のある最重症例であり、小児循環器科、産科、新生児科、心臓血管外科、麻酔科、集中治療科が分娩の時期と方法、出生直後に予測される緊急対応について何度も協議を行った。33週3日に左室機能が更に低下し、帝王切開で分娩となった。体重2,650gで全身浮腫を認めた。出生後、直ちに人工呼吸管理が始まったが、卵円孔の狭小化が強く、酸素飽和度70%台と酸素化不良のため、生後2時間で心房中隔欠損作成術と両側肺動脈絞扼術を施行した。生後2日に経皮的バルーン大動脈弁拡大術を施行した。左室駆出率は34%から44%に改善した。その後、段階的に経皮的バルーン大動脈弁拡大術を施行し、生後51日に大動脈弓峡部の順行性血流を初めて認め、左室駆出率は45%に改善した。生後4ヵ月で2心室修復に到達できた。胎児水腫を伴う致死的疾患な病態のcritical ASに対してチーム医療を行い救命するだけでなく、左室の発育を待ち2心室修復に到達できた。関連各科が医療情報を共有することで迅速な対応が可能であった。(著者抄録)
- T. Hattori; M. Hayakawa; M. Ito; Y. Sato; K. Tamakoshi; Y. Kanamorit; H. Okuyama; N. Inannura; S. Takahashi; Y. Fujino; T. Taguchi; N. UsuiJOURNAL OF PERINATOLOGY 37 3 265 - 269 2017年03月 [査読有り]
OBJECTIVE: To seek a simple approach for prenatally classifying congenital diaphragmatic hernia (CDH) severity using fetal magnetic resonance imaging (MRI) markers. STUDY DESIGN: A retrospective, multicenter study using questionnaires to investigate fetal MRI findings. We included fetuses prenatally diagnosed with isolated left-sided CDH and delivered after 36 weeks of gestation. We focused on three fetal MRI morphological signs: incomplete pulmonary baseline (IPB), liver up (LU) and retrocardiac stomach (RCS). We also evaluated the fetal MRI score defined as the total number of positive signs; the primary outcome was survival at discharge. RESULTS: In 256 patients (from 56 institutions), IPB, LU and RCS findings correlated with lower survival: odds ratio (95% confidence interval), 0.16 (0.08 to 0.33); 0.24 (0.12 to 0.51); and 0.14 (0.07 to 0.28); respectively. Patients with higher fetal MRI scores had a higher mortality rate. CONCLUSION: IPB, LU and RCS on fetal MRI are related to CDH severity. - 重度の呼吸障害とPPHNを呈しECMOで救命し得た静脈管無形性の一例木村 丈; 野崎昌俊; 平野慎也; 白石 淳; 望月成隆; 文 一恵; 稲村 昇; 太田志代; 北島博之周産期・新生児医学雑誌 32 1199 - 1204 2017年 [査読有り]
- Masaya Yamoto; Noboru Inamura; Keita Terui; Kouji Nagata; Yutaka Kanamori; Masahiro Hayakawa; Yuko Tazuke; Akiko Yokoi; Hajime Takayasu; Hiroomi Okuyama; Koji Fukumoto; Naoto Urushihara; Tomoaki Taguchi; Noriaki UsuiJOURNAL OF PEDIATRIC SURGERY 51 12 1926 - 1930 2016年12月 [査読有り]
Background/purpose: The purpose of this study was to investigate echocardiographic parameters in relation to the outcomes of isolated left-sided congenital diaphragmatic hernia (CDH). Methods: This multicenter, retrospective, observational study was conducted among patients with CDH born between 2006 and 2010. Patients in this study did not have severe cardiac malformations or chromosomal aberrations. Patients with incomplete echocardiographic examinations were excluded. In total, 84 patients with left-sided isolated CDH were included in this study. The prognostic parameters were obtained from postnatal echocardiographic images within 24 h after birth. Results: Eight patients died before 90 days of birth. Univariate analysis showed that the presence of continuous right to left shunt at the ductus, left pulmonary artery diameter of <2.7 mm, right pulmonary artery diameter of <3.3 mm, and left ventricular diastolic diameter of <10.8 mm, were the predictors of poor prognosis. Multivariate logistic regression analysis showed that right pulmonary artery diameter of <3.3 mm (adjusted OR 10.28, 95% C.I.: 1.15-249.19) and left ventricular diastolic diameter of <10.8 mm (adjusted OR 7.86, 95% C.I.: 1.01-82.82) were predictors of poor prognosis. Conclusions: This study revealed that the predictors of poor prognosis associated with CDH include smaller right pulmonary artery and left ventricular diastolic diameters. Retrospective Study-Level II. (C) 2016 Published by Elsevier Inc. - Noboru Inamura; Seigo Hira; Shigemitsu IwaiPEDIATRICS INTERNATIONAL 58 12 1375 - 1376 2016年12月 [査読有り]
- 三尖弁異形成およびEbstein病の胎児心エコー検査における予後予測因子の検討鳥越 史子; 稲村 昇; 江見 美杉; 松尾 久実代; 田中 智彦; 平野 恭悠; 青木 寿明; 河津 由紀子; 小垣 滋豊; 大薗 恵一; 萱谷 太日本小児循環器学会雑誌 32 Suppl.1 s1 - 180 (NPO)日本小児循環器学会 2016年07月 [査読有り]
- 三好 剛一; 前野 泰樹; 左合 治彦; 稲村 昇; 川滝 元良; 堀米 仁志; 与田 仁志; 竹田津 未生; 生水 真紀夫; 萩原 聡子; 尾本 暁子; 白石 公; 上田 恵子; 桂木 真司; 池田 智明; 胎児不整脈治療班日本周産期・新生児医学会雑誌 52 2 499 - 499 (一社)日本周産期・新生児医学会 2016年06月
- 森 大樹; 樋渡 勝平; 河島 茉澄; 野村 美緒子; 井深 奏司; 清水 真理子; 平野 恭悠; 稲村 昇; 萱谷 太; 井上 雅美; 奈良 啓悟; 曹 英樹; 臼井 規朗日本小児外科学会雑誌 52 3 676 - 676 (一社)日本小児外科学会 2016年05月 [査読有り]
- Noboru Inamura; Tomohiko Tanaka; Akio Kubota; Yuko Tazuke; Akihiro Yoneda; Hisayuki Kawahara; Futoshi KayataniJournal of Pediatric Surgery Case Reports 6 17 - 19 2016年03月 [査読有り]
We experienced a case of severe congenital diaphragmatic hernia (CDH) with severe deleterious hypoxemia after birth in which we succeeded in saving the patient with radical surgery. Observation of the patient's detailed hemodynamics was possible for the entire perioperative period. The central venous pressure (CVP) was high according to the pressure in the liver. The CVP subsequently decreased after the operation, and the oxygen saturation increased. Therefore, the cardiac diastolic disorder improved. This case suggests that the diastolic dysfunction in severe CDH patients is worsen by compression from herniated visceral organs. - Nao Kanagawa; Noboru Inamura; Yuji TominagaCARDIOLOGY IN THE YOUNG 26 3 612 - 614 2016年03月 [査読有り]
In this study, we present the case of an extremely low birth weight infant with severe coarctation of the aorta after ductus ligation. We treated the patient with balloon angioplasty using the descending aorta as a new access route. This method reduced many complications typically observed during the intervention for extremely low birth weight infants, which may expand the available treatment options for extremely low birth weight infants. - 心筋炎に対する循環補助で救命できなかった新生児コクサッキーB3重症感染症の1例平野 恭悠; 萱谷 太; 杉辺 英世; 江見 美杉; 松尾 久美代; 田中 智彦; 青木 寿明; 河津 由紀子; 稲村 昇; 白石 淳日本小児科学会雑誌 120 2 412 - 412 (公社)日本小児科学会 2016年02月 [査読有り]
- Yoichiro Ishii; Takashi Miyamoto; Kimiko Nakajima; Kensuke Tanaka; Kentaro Ikeda; Noboru Inamura; Takeshi Takagi; Tomio Kobayashi; Hirokazu ArakawaPEDIATRICS INTERNATIONAL 58 2 158 - 161 2016年02月 [査読有り]
Left pulmonary artery sling (LPAS) is a rare vascular anomaly. The left pulmonary artery arises distally from the right pulmonary artery on the right side of the trachea and passes between the trachea and esophagus towards the left lung, compressing the lower trachea. LPAS is associated with congenital tracheal stenosis, which frequently requires early surgical intervention and has a poor prognosis due to severe airway obstruction after birth. Therefore, LPAS should be prenatally diagnosed to prepare for surgical intervention for tracheal stenosis. To the best of our knowledge, there are few reports on prenatal echocardiographic findings in LPAS. We report three prenatal cases of LPAS, which resulted in respiratory symptoms. We discuss fetal ultrasound findings and highlight the abnormal rotation of the fetal cardiac axis to the right as a useful sign in the prenatal screening of LPAS. - Keita Terui; Kouji Nagata; Miharu Ito; Masaya Yamoto; Masayuki Shiraishi; Tomoaki Taguchi; Masahiro Hayakawa; Hiroomi Okuyama; Hideo Yoshida; Kouji Masumoto; Yutaka Kanamori; Keiji Goishi; Naoto Urushihara; Motoyoshi Kawataki; Noboru Inamura; Osamu Kimura; Tadaharu Okazaki; Katsuaki Toyoshima; Noriaki UsuiPEDIATRIC SURGERY INTERNATIONAL 31 10 891 - 897 2015年10月 [査読有り]
Purpose The optimal surgical approach for neonatal congenital diaphragmatic hernia (CDH) remains unclear. We conducted a systematic review and meta-analysis of the effectiveness of endoscopic surgery (ES) for neonatal CDH. Methods A systematic literature search was conducted using MEDLINE and the Cochrane Library. Studies that compared surgical approaches for neonatal CDH were selected. Mortality and recurrence of herniation were analyzed as primary endpoints. Each study was evaluated following the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system. Results Eight observational studies comparing ES and open surgery (OS) met the criteria. As compared with the OS group, the ES group showed both a significantly lower mortality rate [risk ratio (RR) 0.18, 95 % confidence interval (CI) 0.09-0.38, p < 0.0001] and a significantly higher recurrence rate (RR 3.10, 95 % CI 1.95-4.88, p < 0.00001). However, serious selection bias was seen in seven of the eight studies-because the indication of ES had been determined intentionally, the ES groups may have included less severe cases. Conclusion Although the evidence was insufficient, ES was clearly associated with more recurrence than was OS. Therefore, ES should not be the routine treatment for every neonate. It is crucially important to select suitable cases for ES. - Tomohiko Tanaka; Noboru Inamura; Ryo Ishii; Futoshi Kayatani; Akihiro Yoneda; Yuko Tazuke; Akio KubotaPEDIATRIC SURGERY INTERNATIONAL 31 10 905 - 910 2015年10月 [査読有り]
Objective The measurement of diastolic wall strain (DWS), a new method of evaluating cardiac diastolic function, was employed to evaluate ventricular diastolic function in patients with congenital diaphragmatic hernia (CDH). Materials and methods Eighteen neonates with a CDH who were born and treated in our hospital between September 2009 and January 2013 were studied. The left ventricular posterior wall thickness during the systolic phase (PWs) and diastolic (PWd) phase was measured using M-mode imaging, and the DWS was calculated as (PWs-PWd)/PWs. The Tei index, the isovolumic relaxation time (IRT), and the fraction shortening (FS) were measured as indices of cardiac function in 14, 15, and 18 cases, respectively. Cardiac function was measured before and after surgery. Statistical analyses were performed using the paired t test. Results The pre- and postoperative DWS, Tei index, IRT and FS values were 0.19 +/- A 0.06 and 0.26 +/- A 0.11 (P < 0.01), 0.40 +/- A 0.12 and 0.31 +/- A 0.11 (P < 0.05), 48 +/- A 14 and 39 +/- A 5.0 ms (P < 0.05), 30 +/- A 7.7 and 34 +/- A 7.4 % (P < 0.05), respectively. Conclusion The diastolic and systolic functions were not only measured by the Tei index, IRT and FS values, but also by the DWS value, which improved after surgery. The measurement of DWS is an easy and useful method for evaluating the diastolic function of CDH patients. - Ryota Higeno; Noboru Inamura; Futoshi KayataniCARDIOLOGY IN THE YOUNG 25 7 1399 - 1402 2015年10月 [査読有り]
We recently diagnosed two cases of isolated unilateral absence of the pulmonary artery just after birth. Through the therapy, we could not prevent obstruction of the pulmonary artery and lead to complications. There have been no symptoms attributed to isolated unilateral absence of the pulmonary artery so far. We should carefully consider the strategy for therapeutic intervention for asymptomatic cases. - Noboru Inamura; Noriaki Usui; Hiroomi Okuyama; Kouji Nagata; Yutaka Kanamori; Yuji Fujino; Shigehiro Takahashi; Masahiro Hayakawa; Tomoaki TaguchiPEDIATRICS INTERNATIONAL 57 4 682 - 686 2015年08月 [査読有り]
BackgroundThe aim of this study was to clarify how extracorporeal membrane oxygenation (ECMO) is used to treat congenital diaphragmatic hernia (CDH) in Japan. MethodsWe completed a nationwide survey of CDH involving 614 infants. The subjects included 43 patients who underwent ECMO. We compared the clinical data of the patients who did and did not survive 90 days, and analyzed the 24h blood gas data in isolated CDH cases in both groups. ResultsOf the 43 CDH patients, non-isolated CDH associated with other life-threatening or chromosomal anomalies was diagnosed in six patients. Only one of these six patients was able to discontinue ECMO and survived, and the other five died shortly after birth. The other 37 patients all had isolated CDH. The reason for initiating ECMO in 31 of these patients was persistent pulmonary hypertension of the newborn (PPHN). In the 37 patients with isolated CDH, ECMO was initiated within 24h after birth. Sixteen patients (37%) survived 90 days, and intact discharge was possible in eight cases. Among the isolated CDH patients, on ROC analysis of the lowest oxygenation index (OI) to predict 90 day survival, the cut-off was 15. ConclusionsECMO is used to treat PPHN starting from an early period after birth, but the mortality and morbidity are not favorable. For lowest OI, the index used to predict survival following ECMO, the cut-off was 15. - 田中 智彦; 稲村 昇; 萱谷 太; 臼井 規朗; 曹 英樹; 田附 裕子日本小児外科学会雑誌 51 3 568 - 568 (一社)日本小児外科学会 2015年05月
- Yukiko Kawazu; Noboru Inamura; Ryo Ishii; Yoshino Terashima; Yuji Hamamichi; Futoshi Kayatani; Shigemitsu Iwai; Hiroaki Kawata; Hidefumi KishimotoPEDIATRICS INTERNATIONAL 57 2 210 - 216 2015年04月 [査読有り]
BackgroundTetralogy of Fallot with absent pulmonary valve (TF/APV) is a rare and severe congenital heart disease with high mortality. The aim of this study was to assess whether TF/APV prognosis is related to fetal and postnatal clinical course and pulmonary artery (PA) configuration. MethodsThe fetal and postnatal echocardiograms and clinical outcomes of 13 patients with TF/APV (diagnosed antenatally in 9 patients and postnatally in 4) were reviewed, and divided into two groups: group A (n = 6), alive; and group D (n = 7), dead. ResultsFetal period: group A, polyhydramnios n = 0, hydrops fetalis (HF) n = 0, patent ductus arteriosus (PDA) n = 2; group D, polyhydramnios n = 3, HFn = 2, PDAn = 0. Postnatal period: group A, five patients underwent intracardiac repair, including one requiring artificial ventilation (AV). A further AV patient required three operations before extubation. Postoperative courses were all good. Group D, excluding the two intrauterine fetal deaths, four patients required AV (three of whom died neonatally or in early childhood) and one underwent intracardiac repair. PA configuration: all group A patients had bulbous expansion of left and right PA (clover type). Three patients in group D had bulbous expansion of main PA (balloon type). ConclusionsPDA was a factor associated with good prognosis. Hydramnion and HF were factors associated with poor prognosis. Given that there was a higher rate of postnatal AV and poorer prognosis in balloon type than in clover type PA (P < 0.05), PA configuration is also considered an important factor to predict postnatal outcome in TF/APV. - Takekazu Miyoshi; Yasuki Maeno; Haruhiko Sago; Noboru Inamura; Satoshi Yasukouchi; Motoyoshi Kawataki; Hitoshi Horigome; Hitoshi Yoda; Mio Taketazu; Makio Shozu; Masaki Nii; Hitoshi Kato; Akiko Hagiwara; Akiko Omoto; Wataru Shimizu; Isao Shiraishi; Heima Sakaguchi; Kunihiro Nishimura; Michikazu Nakai; Keiko Ueda; Shinji Katsuragi; Tomoaki IkedaCIRCULATION JOURNAL 79 4 854 - 861 2015年04月 [査読有り]
Background: Because there is limited information on fetal bradyarrhythmia associated with congenital heart defects (CHD), we investigated its prognosis and risk factors. Methods and Results: In our previous nationwide survey of fetal bradyarrhythmia from 2002 to 2008, 38 fetuses had associated CHD. Detailed clinical data were collected from secondary questionnaires on 29 fetuses from 18 institutions, and were analyzed. The 29 fetuses included 22 with isomerism, 4 with corrected transposition of the great arteries (TGA) and 3 with critical pulmonary stenosis; 14 had complete atrioventricular block (AVB), 8 had second-degree AVB, and 16 had sick sinus syndrome; 5 died before birth, and 10 died after birth (5 in the neonatal period). Neonatal and overall survival rates for fetal bradyarrhythmia with CHD were 66% and 48%, respectively. Pacemaker implantation was needed in 17 cases (89%). Beta-sympathomimetics were administered in utero in 13 cases and were effective in 6, but were not associated with prognosis. All cases of corrected TGA or ventricular rate >= 70 beats/min survived. A ventricular rate <55 beats/min had significant effects on fetal myocardial dysfunction (P=0.02) and fetal hydrops (P=0.04), resulting in high mortality. Conclusions: The prognosis of fetal bradyarrhythmia with CHD is still poor. The type of CHD, fetal myocardial dysfunction, and fetal hydrops were associated with a poor prognosis, depending on the ventricular rate. - 両側肺動脈絞扼術後のNorwood-Glenn術を経てFontanに達した群の肺循環と臨床的特徴豊川 富子; 浜道 裕二; 金川 奈央; 田中 智彦; 平野 恭悠; 青木 寿明; 河津 由紀子; 稲村 昇; 萱谷 太日本小児科学会雑誌 119 2 279 - 279 (公社)日本小児科学会 2015年02月 [査読有り]
- gamma-glutamyl transpeptidase値の上昇によるFontan術後における肝障害の原因の推定浜道 裕二; 金川 奈央; 豊川 富子; 田中 智彦; 平野 恭悠; 青木 寿明; 河津 由紀子; 稲村 昇; 萱谷 太日本小児科学会雑誌 119 2 451 - 451 (公社)日本小児科学会 2015年02月 [査読有り]
- 胎児心エコーにおける「小さな左室」の経過河津 由紀子; 稲村 昇; 金川 奈央; 豊川 冨子; 田中 智彦; 平野 恭悠; 青木 寿明; 浜道 裕二; 萱谷 太日本小児科学会雑誌 119 2 452 - 452 (公社)日本小児科学会 2015年02月 [査読有り]
- 乳児心室中隔欠損におけるcreatinine上昇の原因の推定浜道 裕二; 金川 奈央; 豊川 富子; 田中 智彦; 平野 恭悠; 青木 寿明; 河津 由紀子; 稲村 昇; 萱谷 太日本小児科学会雑誌 119 2 453 - 453 (公社)日本小児科学会 2015年02月 [査読有り]
- Fontan術前のstressとAntithrombin活性値の低下浜道 裕二; 金川 奈央; 豊川 富子; 田中 智彦; 平野 恭悠; 青木 寿明; 河津 由紀子; 稲村 昇; 萱谷 太日本小児科学会雑誌 119 2 497 - 497 (公社)日本小児科学会 2015年02月 [査読有り]
- 稲村 昇Journal of Pediatr Surg Case Report 6 17 - 19 2015年 [査読有り]
- Y. Kawazu; N. Inamura; N. Shiono; N. Kanagawa; J. Narita; Y. Hamamichi; F. KayataniULTRASOUND IN OBSTETRICS & GYNECOLOGY 44 6 682 - 687 2014年12月 [査読有り]
Objectives To review the fetal echocardiograms of patients with total anomalous pulmonary venous connection (TAPVC) in order to determine whether the distance between the left atrium and the descending aorta would be useful in the prenatal diagnosis of fetal TAPVC. Methods We reviewed the fetal echocardiograms of eight cases of TAPVC (five supracardiac type and three infracardiac type) with no other cardiac malformations. We evaluated the ratio of the left atrium-descending aorta distance to the diameter of the descending aorta ('post-LA space index') in 101 normal and eight TAPVC fetuses, and compared the values between groups. In addition, we examined the tricuspid valve/mitral valve diameter ratio (TVD/MVD) and the right ventricular end-diastolic diameter/left ventricular end-diastolic diameter ratio (RVDd/LVDd). Results The echocardiograms for fetuses with TAPVC and normal fetuses were performed at mean gestational ages of 27.5weeks and 29.6 weeks, respectively. There were no significant differences in the TVD/MVD and RVDd/LVDd ratios between the groups. However, the post-LA space index was significantly higher in the TAPVC cases (mean, 1.51) than it was in the normal fetuses (mean, 0.71 +/- 0.23) (P < 0.0001). On an analysis of the receiver-operating characteristics curve, a post-LA space index cut-off of 1.27 was found to be optimal for distinguishing between TAPVC and normal hearts, with a sensitivity of 100% and specificity of 99%. Conclusions The novel post-LA space index could potentially be used for the prenatal diagnosis of TAPVC. A diagnosis of TAPVC is very likely in cases with a post-LA space index of >1.27. Copyright (c) 2014 ISUOG. Published by John Wiley & Sons Ltd. - Yoichiro Ishii; Noboru Inamura; Futoshi Kayatani; Shigemitsu Iwai; Hiroaki Kawata; Hirokazu Arakawa; Hidefumi KishimotoINTERACTIVE CARDIOVASCULAR AND THORACIC SURGERY 19 5 807 - 811 2014年11月 [査読有り]
Bilateral pulmonary artery banding is considered as 'first-stage' palliation for neonates who have hypoplastic left heart syndrome. This study aimed to identify risk factors that influence outcome before the bidirectional Glenn operation. This retrospective evaluation involved 30 consecutive patients with hypoplastic left heart syndrome, or a variant, who underwent bilateral pulmonary artery banding between August 2005 and December 2011 at our institution. Clinical echocardiographic, operative and catheter examination data were reviewed. This study included 9 patients with hypoplastic left heart syndrome and 21 patients with variants. Bilateral pulmonary artery banding was performed at a median age of 7 days. Finally, 19 patients had the bidirectional Glenn operation performed (Group A), and the remaining 11 patients died before the bidirectional Glenn procedure (Group NA). Catheter evaluations before the bidirectional Glenn procedure were carried out at 97 +/- 34 days. The mean pulmonary venous wedge pressure was significantly lower (Group A: 13.1 +/- 3.1 mmHg vs Group NA: 22.9 +/- 3.7 mmHg, P < 0.01), systemic ventricular ejection fraction was higher (54.4 +/- 10.7 vs 41.7 +/- 9.9%, P < 0.05), systemic ventricular end-diastolic pressure was lower (6.1 +/- 2.4 vs 10.5 +/- 3.6 mmHg, P < 0.05) and the rate of patients with more than mild systemic atrioventricular valve regurgitation was lower in Group A than in Group NA (15.7 vs 62.5%, P < 0.05). Multivariate logistic regression analysis showed that mean pulmonary venous wedge pressure was the most significant predictor of attaining the bidirectional Glenn anastomosis (odds ratio: 2.35, P < 0.01). Postoperative atrioventricular valve regurgitation, cardiac function and mean pulmonary venous wedge pressure are closely correlated with mortality after bilateral pulmonary artery banding. Additional treatments, including operations, are considered to maintain cardiac function and not to raise pulmonary venous wedge pressure before the bidirectional Glenn procedure. - Noboru Inamura; Akio Kubota; Ryo Ishii; Yoichiro Ishii; Yukiko Kawazu; Yuji Hamamichi; Akihiro Yoneda; Hisayuki Kawahara; Hiroomi Okuyama; Futoshi KayataniPEDIATRIC SURGERY INTERNATIONAL 30 9 889 - 894 2014年09月 [査読有り]
The purpose of this study is to evaluate the outcome of our therapeutic strategy for antenatally diagnosed congenital diaphragmatic hernia (ADCDH). We treated 61 cases of ADCDH according to our strategy. Prostaglandin E1 was required to be maintained the patency of the ductus arteriosus (PDA) in 39 cases (Group I) while it was not administered in 22 cases (Group II). Left ventricular end-diastolic dimension (LVDD) and Tei index were measured with echocardiography on days 0, 2, and 7 after birth. Radical surgery was performed on all cases by day 2. On day 0, Group I showed smaller LVDD and Tei index than those in Group II. Between day 0 and day 2, these parameters increased significantly in Group I, but not in Group II. On day 7, no significant difference in these parameters was observed between the two groups. Five patients died of cardiac and respiratory failure, resulting in a survival rate of 92 %. Our therapeutic strategy improves the clinical outcome of ADCDH. This can be attributed to two factors: earlier surgery resulting in improved LV function. The latter attenuates pulmonary hypertension and maintains PDA with a consequent decrease in right ventricular afterload to compensate for the low cardiac output resulting from PDA. - Nobuko Shiono; Noboru Inamura; Shigehiro Takahashi; Kouji Nagata; Yuji Fujino; Masahiro Hayakawa; Noriaki Usui; Hiroomi Okuyama; Yutaka Kanamori; Tomoaki Taguchi; Hisanori MinakamiPEDIATRICS INTERNATIONAL 56 4 553 - 558 2014年08月 [査読有り]
BackgroundThe aim of this study was to clarify the outcome of patients with cardiovascular malformation (CVM) among those with congenital diaphragmatic hernia (CDH) who are indicated for the Fontan procedure. MethodsThe subjects included 76 CDH patients with CVM recruited from a national survey of 614 CDH patients. The outcomes were evaluated between two groups divided according to indication for the Fontan procedure. Patients with functional univentricular disease were considered to be candidates for the Fontan procedure. ResultsSixteen (21.1%) of the 76 patients were candidates for the Fontan procedure, accounting for 2.6% of all 614 patients with CDH. None of these patients, however, underwent the Fontan procedure. Among the 16 patients, the absence of obstruction of the left ventricular outflow tract (LVOTO) was significantly associated with better 90day survival (71.4%, 5/7, for those without LVOTO vs 0.0%, 0/9, for those with LVOTO, P = 0.0007). After excluding 22 patients with chromosomal and/or genetic abnormalities or syndromes, the 90day survival rate was significantly better in neonates without than with indication for the Fontan procedure (62.5%, 25/40 vs 28.6%, 4/14, P = 0.0271). ConclusionsPatients with indications for the Fontan procedure are rare, and the outcome of patients with LVOTO among those with CDH is especially poor. - Noriaki Usui; Hiroomi Okuyama; Yutaka Kanamori; Kouji Nagata; Masahiro Hayakawa; Noboru Inamura; Shigehiro Takahashi; Tomoaki TaguchiJOURNAL OF PEDIATRIC SURGERY 49 8 1191 - 1196 2014年08月 [査読有り]
Background/Purpose: The purpose of this study was to clarify the relationship between the lung to thorax transverse area ratio (L/T ratio) and the observed to expected lung area to head circumference ratio (O/E LHR), based on the results of a nationwide Japanese survey conducted in 2011, and to evaluate the compatibility of these prognostic predictors of fetal CDH. Methods: Two hundred and forty-two prenatally diagnosed isolated CDH patients born between 2006 and 2010 were included in the present analysis. A regression analysis was conducted to investigate the relationship between the L/T ratio and the O/E LHR based on 191 simultaneous measurements of these parameters in 120 patients. Results: The linear regression equation between the L/T ratio and the O/E LHR was: L/T ratio = 0.0233 + (0.00222 x O/E LHR), (R = 0.847, p < 0.0001). According to this equation, 25% of the O/E LHR, the cut-off value used in the fetal intervention for CDH, was equivalent to an L/T ratio of 0.08, a commonly accepted cut-off value for identifying the most severe cases of fetal CDH. Conclusions: As there is a positive correlation between the L/T ratio and the O/E LHR, these two parameters proved to be used interchangeably according to the linear regression equation. (C) 2014 Elsevier Inc. All rights reserved. - 三好 剛一; 前野 泰樹; 左合 治彦; 稲村 昇; 川滝 元良; 堀米 仁志; 与田 仁志; 生水 真紀夫; 萩原 聡子; 尾本 暁子; 白石 公; 上田 恵子; 桂木 真司; 池田 智明日本周産期・新生児医学会雑誌 50 2 775 - 775 (一社)日本周産期・新生児医学会 2014年06月
- 三好 剛一; 前野 泰樹; 左合 治彦; 稲村 昇; 安河内 聰; 川滝 元良; 堀米 仁志; 与田 仁志; 竹田津 未生; 新居 正基; 生水 真紀夫; 賀藤 均; 白石 公; 坂口 平馬; 上田 恵子; 桂木 真司; 池田 智明日本小児循環器学会雑誌 30 Suppl. s253 - s253 (NPO)日本小児循環器学会 2014年06月
- Noriaki Usui; Kouji Nagata; Masahiro Hayakawa; Hiroomi Okuyama; Yutaka Kanamori; Shigehiro Takahashi; Noboru Inamura; Tomoaki TaguchiEUROPEAN JOURNAL OF PEDIATRIC SURGERY 24 1 31 - 38 2014年02月 [査読有り]
IntroductionPneumothorax remains a life-threatening complication that occurs in congenital diaphragmatic hernia (CDH), even under respiratory management with gentle ventilation. The aim of this study was to evaluate the prevalence of pneumothoraces as a fatal complication during the management of CDH based on the results of a nationwide Japanese survey conducted in the era of gentle ventilation. Materials and MethodsA retrospective cohort study was performed as part of a nationwide Japanese survey of CDH. A total of 510 neonates with isolated CDH born between 2006 and 2010 were included in this study. The patients were divided into four groups according to operative findings related to the diaphragmatic defect size and operability, which represents the disease severity: defects less than 25%, defects more than 25% but less than 75%, defects more than 75%, and a patient group that was unable to undergo surgery. The prevalence of pneumothorax and the survival rate were compared with respect to each disease severity group. Each case was evaluated to determine whether the development of a pneumothorax was the primary cause of death. ResultsOf the 510 neonates with isolated CDH, 69 patients developed a pneumothorax before and/or after surgical intervention. Of the 69 patients 38 patients died, and only 26 patients were discharged from the hospital without any major morbidity that requires home treatment (intact discharge). The prevalence of pneumothorax increased and the survival rate and intact discharge rate decreased as the severity of the disease worsened. The number of patients whose pneumothorax was presumed to be the primary cause of death also increased as the severity of the disease worsened. The survival rate of the patients with pneumothorax was significantly lower than that of the patients without pneumothorax among the groups with 25 to 75% defects and 75% or more defects. ConclusionsPneumothoraces was found to more likely occur in neonates with CDH associated with a large defect of the diaphragm. The survival rate and intact discharge rate decreased as the severity of the disease worsened, especially among the patients who developed pneumothorax accompanied by large diaphragmatic defects. No other risk factors related to pneumothorax occurrence were found, except for the severity of the disease itself, thus suggesting that pneumothorax was associated with a lethal outcome in neonates with CDH associated with a large defect of the diaphragm. - 高安肇; 増本幸二; 田口智章; 臼井規朗; 奥山宏臣; 早川昌弘; 金森豊; 吉田英生; 稲村昇; 中村知夫; 五石圭司胎児・新生児肺低形成の診断・治療実態に関する調査研究 平成25年度 総括・分担研究報告書 91 - 99 2014年
- Ryo Ishii; Noboru Inamura; Akio Kubota; Futoshi Kayatani; Mayumi Shimada; Keisuke Ishii; Nobuhiro Hidaka; Nobuaki MitsudaJournal of Pediatric Surgery Case Reports 2 1 15 - 19 2014年 [査読有り]
We report a case of severe congenital diaphragmatic hernia accompanied by hydrops fetalis in a fetus conceived by a 33-year-old woman. Fetal magnetic resonance imaging performed at 27 weeks of gestation revealed herniation of the stomach, bowel, and left liver into the thoracic cavity, confirming severe left-sided CDH. Presence of hydrops fetalis at 32 weeks of gestation and its progression over the next 2 weeks was confirmed by fetal echography. Subsequently, fetal echocardiography revealed severe tricuspid regurgitation and reverse flow in the inferior vena cava at 33 weeks, with abnormal left and right ventricular Tei indices, extended left ventricular isovolumetric relaxation time, and increased preload index. Maternal hyperoxygenation (MHO) therapy was initiated at 35 weeks of gestation to increase pulmonary blood flow and promote venous return to the left ventricle. The hydrops was attenuated by MHO for 2 weeks, and fetal echocardiography demonstrated improved cardiac performance. A female infant was born at 37 weeks of gestation and underwent diaphragmatic repair shortly after birth. She survived surgery and was discharged at 4 months of age with no adverse sequelae. This case report suggests that MHO may be a potential therapy for severe congenital diaphragmatic hernia associated with hydrops fetalis. Crown Copyright © 2014 Published by Elsevier Inc. - シリコン栓での気管支充填術により救命しえたFontan術後難治性気道出血の小児例林 麻子[中田]; 河津 由紀子; 稲村 昇; 石井 良; 浜道 裕二; 萱谷 太大阪府立母子保健総合医療センター雑誌 29 1 57 - 61 (地独)大阪府立病院機構大阪母子医療センター 2013年12月症例は5歳女児。先天性心疾患に対し3歳時にFontan手術が行われ、術後経過は良好であった。散歩中に血液の大量嘔吐を認め、救急搬送。気道出血と診断されたが出血を繰り返すため、ヘリコプターで当センターへ緊急搬送となった。側副血管に対しコイル塞栓術を何度も行ったが大量出血が継続したため、救命的にシリコン製のEndobronchial Watanabe Spigot(EWS)による気管支充填術を施行した。難治性の気道出血であったが、側副血管へのコイル塞栓術およびEWSによる気管支充填術の併用により救命することができた。本症例は小児で初めてのEWSによる気管支充填術施行例である。術後急性期にEWSの脱落および再充填などを要したが以後は明らかな合併症なく経過しており、EWSは難治性の気道出血においてコイル塞栓術との併用も考慮すべき治療法であると考えた。今後はEWSの長期留置に伴う合併症に注意しながら経過観察の予定である。(著者抄録)
- Shigehiro Takahashi; Haruhiko Sago; Yutaka Kanamori; Masahiro Hayakawa; Hiroomi Okuyama; Noboru Inamura; Yuji Fujino; Noriaki Usui; Tomoaki TaguchiPEDIATRICS INTERNATIONAL 55 4 492 - 497 2013年08月 [査読有り]
Background: Congenital diaphragmatic hernia is associated with cardiovascular malformation. Many prognostic factors have been identified for isolated congenital diaphragmatic hernia; however, reports of concurrent congenital diaphragmatic hernia and cardiovascular malformation in infants are limited. This study evaluated congenital diaphragmatic hernia associated with cardiovascular malformation in infants. Factors associated with prognosis for patients were also identified. Methods: This retrospective cohort study was based on a Japanese survey of congenital diaphragmatic hernia patients between 2006 and 2010. Frequency and outcome of cardiovascular malformation among infants with congenital diaphragmatic hernia were examined. Severity of congenital diaphragmatic hernia and cardiovascular malformation were compared as predictors of mortality and morbidity. Results: Cardiovascular malformation was identified in 76 (12.3%) of 614 infants with congenital diaphragmatic hernia. Mild cardiovascular malformation was detected in 19 (33.9%) and severe cardiovascular malformation in 37 (66.1%). Their overall survival rate at discharge was 46.4%, and the survival rate without morbidity was 23.2%. Mortality and morbidity at discharge were more strongly associated with severity of cardiovascular malformation (adjusted OR 7.69, 95% CI 1.96-30.27; adjusted OR 7.93, 95% CI 1.76-35.79, respectively) than with severity of congenital diaphragmatic hernia. Conclusions: The prognosis for infants with both congenital diaphragmatic hernia and cardiovascular malformation remains poor. Severity of cardiovascular malformation is a more important predictive factor for mortality and morbidity than severity of congenital diaphragmatic hernia. - Tetsuya Isayama; Noboru Inamura; Nobuko Shiono; Hiroyuki KitajimaPediatrics International 55 4 521 - 524 2013年08月 [査読有り]
Complete congenital heart block (CCHB) accompanied with neonatal lupus erythematosus is caused by an immune reaction between maternal anti-Ro/SSA antibodies and the fetal heart and is generally considered an irreversible process. This reaction mostly occurs before 30 weeks' gestation, especially between the 20th and 24th week. Reported here is an atypical case of neonatal lupus erythematosus with CCHB detected after 32 weeks' gestation that showed postnatal improvement in the degree of heart block after preterm delivery and immunoglobulin use. The clinical condition of the infant worsened with an increase in heart rate due to possible cardiomyopathy induced by the immune reaction. © 2013 The Authors. - 田附 裕子; 窪田 昭男; 川原 央好; 米田 光宏; 谷 岳人; 稲村 昇; 竹内 宗之; 木内 恵子; 光田 信明; 北島 博之日本周産期・新生児医学会雑誌 49 2 582 - 582 (一社)日本周産期・新生児医学会 2013年06月
- 田中 智彦; 稲村 昇; 鳥越 史子; 成田 淳; 塩野 展子; 河津 由紀子; 濱道 裕二; 萱谷 太; 窪田 昭男; 川原 央好; 米田 光宏; 田附 裕子日本周産期・新生児医学会雑誌 49 2 639 - 639 (一社)日本周産期・新生児医学会 2013年06月
- 鳥越 史子; 稲村 昇; 田中 智彦; 成田 淳; 塩野 展子; 河津 由紀子; 濱道 裕二; 萱谷 太; 米田 光宏; 田附 裕子; 川原 央好; 窪田 昭男日本周産期・新生児医学会雑誌 49 2 718 - 718 (一社)日本周産期・新生児医学会 2013年06月
- 田中 智彦; 稲村 昇; 鳥越 史子; 成田 淳; 塩野 展子; 河津 由紀子; 濱道 裕二; 萱谷 太; 窪田 昭男; 川原 央好; 米田 光宏; 田附 裕子日本周産期・新生児医学会雑誌 49 2 821 - 821 (一社)日本周産期・新生児医学会 2013年06月
- 臼井 規朗; 早川 昌弘; 奥山 宏臣; 金森 豊; 高橋 重裕; 稲村 昇; 藤野 裕士; 田口 智章日本周産期・新生児医学会雑誌 = Journal of Japan Society of Perinatal and Neonatal Medicine 49 1 149 - 152 (一社)日本周産期・新生児医学会 2013年05月主要施設における新生児横隔膜ヘルニアの治療成績と治療方針の施設間差異について検討した。対象は10例以上の症例を治療した経験のある22施設で、症例調査票を用いて各症例に対する診断、治療、転帰に関する調査を実施した。その結果、出生前診断率、横隔膜ヘルニア単独(Isolated)症例の割合とも施設間により大きな差があり、重症度も施設によって重症例の占める割合に偏りがあった。出生前診断例に対する治療方針についても施設間で異なり、全例帝王切開分娩を施行した施設は9施設あった一方、帝王切開症例の割合が50%未満の施設も4施設あった。胎児麻酔については9施設で全く行っていなかったが、1施設で全例に施行していた。呼吸・循環管理については、全施設で原則としてgentle ventilationの考え方に基づき呼吸管理を行っており、心臓超音波検査を治療方針決定の参考にしていた。一方、人工呼吸器管理上容認できるpre PaCO2の最高値と最低値には開きがあり、NO吸入療法の使用頻度やECMOについても施設間に差異があった。また一定期間待機してから手術を行う施設は11施設、一定のstabilizationの基準を満たせば手術をする施設は10施設、なるべく早期に手術をするのは1施設であったが、実際に待機した時間の中央値には明らかな差はなかった。Isolated症例において比較的早期に手術をしている施設では生存率がやや高い傾向であった。合併症については、気胸、胃食道逆流症などの発症率に施設間差異を認め、Isolated症例の生存率が低かった施設で気胸の発生率が高い傾向であった。
- Masahiro Hayakawa; Miharu Ito; Tetsuo Hattori; Yutaka Kanamori; Hiroomi Okuyama; Noboru Inamura; Shigehiro Takahashi; Kouji Nagata; Tomoaki Taguchi; Noriaki UsuiPEDIATRICS INTERNATIONAL 55 2 190 - 196 2013年04月 [査読有り]
Background During the last decade, new supportive modalities and new therapeutic strategies to treat congenital diaphragmatic hernia (CDH) have been introduced. In Japan, the large number of hospitals prevents centralizing infants with CDH in tertiary centers. The aim of this study was to evaluate the correlations between the number of CDH patients, survival rates, and the current strategies employed to treat CDH at the individual hospitals. Methods Eighty-three hospitals with 674 CDH cases were analyzed using questionnaires. We classified the hospitals into three groups according to the number of CDH patients treated: Group 1 (G1; more than 21 patients), Group 2 (G2; 1120 patients), and Group 3 (G3; fewer than 10 patients). Results The median number of CDH patients in G1, G2, and G3 were 28, 14, and 4, respectively. The overall survival rate was 74.5%. When only the isolated CDH cases with a prenatal diagnosis were included, the overall survival rate was 79.3%. The survival rate of isolated CDH cases with a prenatal diagnosis was significantly higher in G1 than that in G2 or G3 (87.2% vs 75.2% vs 74.3%; P < 0.001). There were no differences in perinatal therapeutic strategies among the three groups. Conclusions We concluded that it might therefore be important to centralize infants with CDH, especially those with isolated CDH with a prenatal diagnosis, to tertiary centers in Japan in order to improve the survival rates. - Kouji Nagata; Noriaki Usui; Yutaka Kanamori; Shigehiro Takahashi; Masahiro Hayakawa; Hiroomi Okuyama; Noboru Inamura; Yuji Fujino; Tomoaki TaguchiJOURNAL OF PEDIATRIC SURGERY 48 4 738 - 744 2013年04月 [査読有り]
Background/Purpose: Few nationwide surveys have been reported regarding the perinatal status, clinical course and postnatal outcome of cases with congenital diaphragmatic hernia (CDH). The aim of this study was to review the current profile and the outcomes of a large cohort of CDH cases in Japan. Methods: A nationwide retrospective cohort study was conducted on neonates diagnosed to have CDH between January 2006 and December 2010. The questionnaires were sent to 159 representative regional institutions and 109 (68.6%) institutions responded to the preliminary survey which had 674 cases. Eleven institutions which had 60 CDH neonates did not respond to the second questionnaire, and 26 institutions had no cases. Finally, 614 CDH neonates from 72 institutions had been collected and were used in the detailed survey. The perinatal status, clinical course and the postnatal outcome were reviewed. Survival was defined as infants alive at hospital discharge, at the time of transfer or still in the hospital at the time of questionnaire, which was confirmed during the period from July 2011 to November 2011 by the investigators. Results: Four hundred sixty-three (75.4%) of 614 CDH neonates survived in this study. The overall survival rate of neonates with isolated CDH was 84.0%. A total of 444 (72.0%) patients were prenatally diagnosed, and had a survival rate of 70.8%. Four hundred thirty-three (70.9%) patients were treated with high-frequency oscillatory ventilation (HFOV) as the initial ventilation, 344 (56.0%) patients received inhaled nitric oxide (iNO) and 43 (7.0%) required extracorporeal membrane oxygenation (ECMO). The overall survival rates of the CDH neonates who had been treated using HFOV, iNO and ECMO were 74.3%, 68.3% and 37.2%, respectively. Conclusions: This study demonstrated that the current status for CDH treatment in Japan and the overall survival rate were comparable to those of recent reports from other countries. (c) 2013 Elsevier Inc. All rights reserved. - 田口智章; 永田公二; 臼井規朗; 奥山宏臣; 早川昌弘; 金森豊; 稲村昇; 中村知夫; 高橋重裕胎児・新生児肺低形成の診断・治療実態に関する調査研究 平成24年度 総括・分担研究報告書 17 - 36 2013年
- Yoichiro Ishii; Noboru Inamura; Futoshi KayataniPEDIATRIC CARDIOLOGY 33 7 1227 - 1229 2012年10月 [査読有り]
- 河津 由紀子; 稲村 昇; 石井 陽一郎; 塩野 展子; 成田 淳; 寺嶋 佳乃; 石井 良; 浜道 裕二; 萱谷 太日本小児循環器学会雑誌 28 Suppl. s235 - s235 (NPO)日本小児循環器学会 2012年06月
- 三好 剛一; 前野 泰樹; 賀藤 均; 稲村 昇; 安河内 聰; 川滝 元良; 堀米 仁志; 与田 仁志; 竹田津 未生; 新居 正基; 白石 公; 坂口 平馬; 上田 恵子; 桂木 真司; 池田 智明日本小児循環器学会雑誌 28 Suppl. s149 - s149 (NPO)日本小児循環器学会 2012年06月
- Yukiko Kawazu; Noboru Inamura; Futoshi Kayatani; Nobuhiko Okamoto; Hiroko MorisakiCARDIOLOGY IN THE YOUNG 22 1 116 - 119 2012年02月 [査読有り]
We report an infantile case of Loeys-Dietz syndrome prenatally diagnosed with congenital complex heart disease - double outlet right ventricle and interruption of the aortic arch. The patient also showed prominent dilatation of the main pulmonary artery. Emergency bilateral pulmonary artery banding was performed on the 9th day. However, on the 21st day, the patient died of massive bleeding due to rupture of the right pulmonary artery. Subsequently, a mutation of the TGEBR1 gene was detected. As cardiovascular lesions of Loeys-Dietz syndrome appear early and progress rapidly, the prognosis is generally poor. Patients require periodic examination and early intervention with medical therapy such as Losartan administration and surgical therapy. Early genetic screening is thought to be useful for the prediction of complications as well as vascular disease. - Miyoshi T; Maeno Y; Sago H; Inamura N; Yasukohchi S; Kawataki M; Horigome H; Yoda H; Taketazu M; Shozu M; Nii M; Kato H; Hayashi S; Hagiwara A; Omoto A; Shimizu W; Shiraishi I; Sakaguchi H; Nishimura K; Ueda K; Katsuragi S; Ikeda TCirculation journal : official journal of the Japanese Circulation Society 76 2 469 - 476 2012年02月 [査読有り]
Background: There are few large studies of fetal congenital bradyarrhythmia. The aim of the present study was to investigate the effects and risks of transplacental treatment for this condition. Methods and Results: Using questionnaires, 128 cases of fetal bradyarrhythmia were identified at 52 Japanese institutions from 2002 to 2008. Of the 128 fetuses, 90 had structurally normal hearts. Among these 90 fetuses, 61 had complete atrioventricular block (CAVB), 16 had second-degree AVB, 8 had sinus bradycardia, and 5 had other conditions. The 61 CAVB fetuses were divided into those who did (n=38) and those who did not (n=23) receive transplacental medication. Monotherapy with beta-sympathomimetics, steroid monotherapy, and combination therapy with these agents was given in 11, 5 and 22 cases, respectively. Beta-sympathomimetics improved bradycardia (P<0.001), but no medication could significantly improve the survival rate. Fetal hydrops was associated with a 14-fold increased risk of perinatal death (P=0.001), and myocardial dysfunction was a significant risk factor for poor prognosis (P=0.034). Many adverse effects were observed with steroid treatment, with fetal growth restriction increasing significantly after >10 weeks on steroids (P=0.043). Conclusions: Treatment with beta-sympathomimetics improved bradycardia, but survival rate did not differ significantly in fetuses with and without transplacental medication. It is recommended that steroid use should be limited to <10 weeks to avoid maternal and fetal adverse effects, especially fetal growth restriction and oligohydramnios. (Circ J 2012; 76: 469-476) - George Hayashi; Noboru Inamura; Futoshi Kayatani; Yukiko Kawazu; Yuuji Hamamichi; Aoki HisaakiPRENATAL DIAGNOSIS 32 2 194 - 196 2012年02月 [査読有り]
- 石井 良; 稲村 昇; 窪田 昭男; 田附 裕子; 米田 光宏; 川原 央好; 萱谷 太日本小児外科学会雑誌 48 3 480 - 480 特定非営利活動法人 日本小児外科学会 2012年
- 稲村 昇; 臼井 規朗; 奧山 宏臣; 田口 智章; 金森 豊; 高橋 繁裕; 早川 昌弘; 藤野 裕士日本小児外科学会雑誌 48 3 479 - 479 特定非営利活動法人 日本小児外科学会 2012年
- 臼井 規朗; 田口 智章; 奥山 宏臣; 金森 豊; 早川 昌弘; 稲村 昇; 高橋 重裕; 藤野 裕士日本小児外科学会雑誌 48 3 479 - 479 特定非営利活動法人 日本小児外科学会 2012年
- 木戸 高志; 岸本 英文; 川田 博昭; 盤井 成光; 小澤 秀登; 萱谷 太; 稲村 昇; 濱道 裕二; 河津 由紀子; 石井 良日本小児循環器学会雑誌 28 6 306 - 310 Japanese Society of Pediatric Cardiology and Cardiac Surgery 2012年背景:扁桃肥大は小児の上気道狭窄の最多原因であり, 上気道狭窄による低酸素血症, 高二酸化炭素血症は, 肺動脈圧の上昇, 慢性肺性心を惹起させる可能性からFontan循環に悪影響を及ぼす可能性がある.
対象:1993年から2009年までの, いわゆるFontan trackにのった全207例中, 扁桃腺摘出術(以下, 扁摘)を行った9例.
方法:扁桃肥大を合併し上気道狭窄が疑われるFontan candidateおよびFontan術後患者に対する扁摘の臨床的効果を, 扁摘前後の, 経皮的動脈血酸素飽和度(SpO2), 扁摘前後に心臓カテーテル検査を行った4例での, 動脈血二酸化炭素分圧(PaCO2), 平均肺動脈圧(mPAP)を用いて検討した.
結果:9例中8例はFontan手術に到達し, 1例は両方向性Glenn術後Fontan待機中である. 扁摘前後のSpO2は, 術前81±7%から術後85±6%に, 全例で上昇した. 扁摘の前後でPaCO2は, 術前41±4 mmHgから術後37±4 mmHgに, 1例を除いて低下し, mPAPは, 術前22±12 mmHgから術後13±4 mmHgに, 全例で低下した.
結論:扁桃肥大を合併し上気道狭窄が疑われるFontan track症例に対する扁摘は, 肺血管抵抗を低下させた可能性があり, Glenn・Fontan循環を改善させることが示唆された. - 林 中田 麻子; 河津 由紀子; 稲村 昇; 石井 良; 浜道 裕二; 萱谷 太日本小児科学会雑誌 116 1 92 - 96 日本小児科学会 2012年01月症例は5歳2ヵ月女児、純型肺動脈閉鎖と胎児診断を受け、段階手術、最終的には3歳時にFontan手術を経てチアノーゼが消失した。無治療の静脈管開存症を合併していたが肝機能に異常はなく、良好な外来経過であった。5歳2ヵ月時、散歩中に突然大量の血液を吐き、救命センターに搬送され、直ちに気管挿管が行われ、気道出血と診断された。到着時、顔面蒼白、頻脈、血圧低下の出血性ショック状態であった。造影CTで右下葉S6と上葉S2を中心とした肺出血が認められた。転院後も出血が続くため、直ちに下行大動脈から右上葉に向かう側副血管にコイル塞栓術を行った。しかし、気道出血が再発し、気管支ファイバースコピーで左肺からの出血を確認したため、左内胸動脈と左鎖骨下動脈から派生する側副血管にコイル塞栓術を行った。気道出血は止まったが、4日後に再度出血を認め、3回の塞栓術でコイル塞栓が可能な側副血管は全て塞栓できたと考えられた。しかし、その後も大量の気道出血を繰り返し、循環動態も悪化するため、気管支側からの止血処置として気管支充填術を選択した。その後も気道出血が継続し、左側からの出血が疑われ、4回目のコイル塞栓術を施行したが著効せず、左下甲状腺動脈より派生する側副血管に対する5回目のコイル塞栓術を施行した。その後は出血を認めず、人工呼吸器から離脱できた。急性期の影響で低酸素性虚血性脳症を呈したが全身状態は良好で、約4ヵ月後に退院した。1年経過したが現在まで気道出血の再発はみられていない。
- Noriaki Usui; Yoshihiro Kitano; Hiroomi Okuyama; Mari Saito; Kouji Masumoto; Nobuyuki Morikawa; Hajime Takayasu; Tomoo Nakamura; Satoshi Hayashi; Motoyoshi Kawataki; Hiroshi Ishikawa; Keisuke Nose; Noboru Inamura; Haruhiko SagoJOURNAL OF PEDIATRIC SURGERY 46 10 1873 - 1880 2011年10月 [査読有り]
Background/Purpose: The aim of this study was to establish a prenatal prognostic classification system for risk-stratified management in fetuses with isolated congenital diaphragmatic hernia (CDH). Methods: Amulti-institutional retrospective cohort study of isolated CDH, diagnosed prenatally in fetuses delivered during the 2002 to 2007 period at 5 participating institutions in Japan, was conducted. The risk stratification system was formulated based on the odds ratios of prenatal parameters for mortality at 90 days. The clinical severity in CDH infants were compared among the stratified risk groups. Results: Patients were classified into the 3 risk groups: group A (n = 48) consisted of infants showing liver-down with contralateral lung-to-thorax transverse area ratio (L/T) ratio >= 0.08; group B of infants showing liver-down with L/T ratio <0.08 or liver-up with L/T ratio >= 0.08 (n = 35), and group C of infants showing liver-up with L/T ratio <0.08 (n = 20). The mortality at 90 days in groups A, B, and C were 0.0%, 20.0%, and 65.0%, respectively. The intact discharge rates were 95.8%, 60.0%, and 5.0%, respectively. This system also accurately reflected the clinical severity in CDH infants. Conclusions: Our prenatal risk stratification system, which demonstrated a significant difference in postnatal status and final outcome, would allow for accurate estimation of the severity of disease in fetuses with isolated CDH, although it needs prospective validation in a different population. (C) 2011 Elsevier Inc. All rights reserved. - 石井 陽一郎; 稲村 昇; 萱谷 太; 濱道 裕二; 河津 由紀子; 高橋 邦彦; 石井 良; 寺嶋 佳乃日本小児循環器学会雑誌 27 Suppl. s210 - s210 (NPO)日本小児循環器学会 2011年06月
- Hisaaki Aoki; Noboru Inamura; Yukiko Kawazu; Masahiro Nakayama; Futoshi KayataniCIRCULATION JOURNAL 75 5 1215 - 1221 2011年05月 [査読有り]
Background: There are few reports describing the features of maternal anti-SSA antibody-associated congenital complete heart block (CCHB) patients developing endocardial fibroelastosis (EFE). The aim of this study was to describe the clinical features and the outcome of patients with CCHB, with or without EFE. Methods and Results: Over a 20-year period, 12 consecutive patients diagnosed with maternal anti-SSA antibody-associated CCHB were identified. The maternal anti-SSA antibody levels were measured and fetal echocardiographic findings were reviewed. The ratios of the thickness of the endocardium to that of the whole wall of the left ventricle (LE/W) and right ventricle (RE/W) were measured to investigate the degree of endocardial thickening. A total of 7 patients survived (living group) and were not diagnosed as having EFE. The remaining 5 patients died and were diagnosed with EFE during autopsy (dead group). Fetal echocardiography of the patients showed differences in the thickening and hyperintensity of the endocardium. The RE/W value was significantly higher in the dead group than in the living group. The titers of both maternal anti-52-kDa and anti-60-kDa SSA antibodies were high, but showed no significant differences between the 2 patient groups. Conclusions: EFE was the major negative prognostic factor for CCHB. Myocardial damage, predominantly in the right ventricle, was related to the outcome of CCHB associated with EFE. (Circ J 2011; 75: 1215-1221) - Hiroomi Okuyama; Yoshihiro Kitano; Mari Saito; Noriaki Usui; Nobuyuki Morikawa; Kouji Masumoto; Hajime Takayasu; Tomoo Nakamura; Hiroshi Ishikawa; Motoyoshi Kawataki; Satoshi Hayashi; Noboru Inamura; Keisuke Nose; Haruhiko SagoPEDIATRIC SURGERY INTERNATIONAL 27 4 373 - 378 2011年04月 [査読有り]
To review the recent Japanese experience with prenatally diagnosed congenital diaphragmatic hernia (CDH) based on a multi-institutional survey. A multicenter, retrospective cohort study was conducted on 117 patients born between 2002 and 2007 with isolated prenatally diagnosed CDH. All patients were managed by maternal transport, planned delivery, immediate resuscitation and gentle ventilation. The primary outcome measurements were the 90-day survival and intact discharge. The examined prenatal factors included gestational age (GA) at diagnosis, lung-to-head ratio (LHR), lung-to-thorax transverse area ratio (L/T) and liver position. Physical growth and motor/speech development were evaluated at 1.5 and 3 years of age. Data were expressed as the median (range). The mean GA at diagnosis was 29 (17-40) weeks. The LHR and L/T were 1.56 (0.37-4.23) and 0.11 (0.04-0.25), respectively. There were 48 patients with liver up. The mean GA at birth was 38 (28-42) weeks. The 90-day survival rate and intact discharge rate were 79 and 63%, respectively. Twelve patients had major morbidity at discharge, and 71% of these patients had physical growth or developmental retardation at 3 years of age. This multicenter study demonstrated that the 90-day survival rate of isolated prenatally diagnosed CDH was 79%, and that subsequent morbidity remained high. A new treatment strategy is needed to reduce the mortality and morbidity of severe CDH. - Kitano Y; Okuyama H; Saito M; Usui N; Morikawa N; Masumoto K; Takayasu H; Nakamura T; Ishikawa H; Kawataki M; Hayashi S; Inamura N; Nose K; Sago HUltrasound Obstet Gynecol 37 3 277 - 282 2011年03月 [査読有り]
OBJECTIVES:
To document outcome and to explore prognostic factors in fetal left congenital diaphragmatic hernia (CDH).
METHODS:
This was a multicenter retrospective study of 109 patients with prenatally diagnosed isolated left CDH born between 2002 and 2007. The primary outcome was intact discharge, defined as discharge from hospital without major morbidities, such as a need for respiratory support including oxygen supplementation, tube feeding, parenteral nutrition or vasodilators. All patients were managed at perinatal centers with immediate resuscitation, gentle ventilation (mostly with high-frequency oscillatory ventilation) and surgery after stabilization. Prenatal data collected included liver and stomach position, lung-to-head ratio, gestational age at diagnosis and presence or absence of polyhydramnios. Stomach position was classified into four grades: Grade 0, abdominal; Grade 1, left thoracic; Grade 2, less than half of the stomach herniated into the right chest; and Grade 3, more than half of the stomach herniated into the right chest.
RESULTS:
Overall intact discharge and 90-day survival rates were 65.1% and 79.8%, respectively. Stomach herniation was classified as Grade 0 in 19.3% of cases, Grade 1 in 45.9%, Grade 2 in 13.8% and Grade 3 in 21.1%. Multivariate analysis revealed that liver position was the strongest prognostic variable for intact discharge, followed by stomach position. Based on our results, we divided patients into three groups according to liver (up vs. down) and stomach (Grade 0-2 vs. Grade 3) position. Intact discharge rates declined significantly from liver-down (Group I), to liver-up with stomach Grade 0-2 (Group II), to liver-up with stomach Grade 3 (Group III) (87.0%, 47.4% and 9.5% of cases, respectively).
CONCLUSION:
Current status and outcomes of prenatally diagnosed left CDH in Japan were surveyed. Stomach herniation into the right chest was not uncommon and its grade correlated with outcome. The combination of liver and stomach positions was useful to stratify patients into three groups (Group I-III) with different prognoses. - Morikawa Nobuyuki; Kitano Yoshihiro; Okuyama Hiroomi; Saito Mari; Usui Noriaki; Masumoto Kouji; Takayasu Hajime; Hayashi Satoshi; Nakamura Tomoo; Ishikawa Hiroshi; Kawataki Motoyoshi; Nose Keisuke; Inamura Noboru; Sago Haruhiko日本小児外科学会雑誌 47 4 540 - 540 特定非営利活動法人 日本小児外科学会 2011年
- Noriaki Usui; Yoshihiro Kitano; Hiroomi Okuyama; Mari Saito; Nobuyuki Morikawa; Hajime Takayasu; Tomoo Nakamura; Satoshi Hayashi; Motoyoshi Kawataki; Hiroshi Ishikawa; Keisuke Nose; Noboru Inamura; Kouji Masumoto; Haruhiko SagoPEDIATRIC SURGERY INTERNATIONAL 27 1 39 - 45 2011年01月 [査読有り]
Purpose An accurate prenatal assessment of the patients' severity is essential for the optimal treatment of individuals with congenital diaphragmatic hernia (CDH). The purpose of this study was to clarify the reliability of the lung to thorax transverse area ratio (L/T) as a prenatal predictive parameter. Methods A multicenter retrospective cohort study was conducted on 114 isolated CDH fetuses with a prenatal diagnosis during the period between 2002 and 2007 at five participating centers in Japan. The relationship between the gestational age and the L/T was analyzed. The most powerful measurement point and accurate cutoff value of the L/T was determined by an analysis of a receiver operating characteristic curve, which was verified by comparing the patients' severity. Results There was a negative correlation between the gestational age and the L/T in the non-survivors, and no correlation in the survivors. There were significant differences in the parameters which represented the patients' severity including the respiratory and circulatory status, the surgical findings, and the final outcomes between the groups divided at 0.080 in the minimum value of the L/T during gestation. Conclusion The L/T was not strongly influenced by the gestational age, and it was found to be a reliable prenatal predictive parameter in fetuses with isolated CDH. - Hidekazu Ishida; Noboru Inamura; Yukiko Kawazu; Futoshi KayataniCONGENITAL HEART DISEASE 6 1 51 - 56 2011年01月 [査読有り]
Objective. Prenatal constriction of the ductus arteriosus associated with maternal drug ingestion was reported several decades ago. There are fewer reports of the complete closure of the ductus arteriosus; therefore, the clinical features of the latter are poorly understood. The aim of this study is to clarify the clinical features of complete ductal closure and postnatal pulmonary hypertension by performing echocardiography of the fetus. Patients. We diagnosed four fetuses with complete ductal closure by performing fetal echocardiography and reviewed the prenatal and postnatal medical records of the mother and fetus. Results. One mother each had bronchial asthma, ulcerative colitis, and idiopathic thrombocytopenic purpura, and they had received nonsteroidal anti-inflammatory drugs and/or corticosteroids during pregnancy. The fourth mother did not have basal disease and had not ingested any drugs. Fetal diagnosis was performed at 32-38 weeks of gestation. All fetuses had right heart dilatation with tricuspid regurgitation in the absence of any cardiac defects, and Doppler echocardiography indicated that the right ventricular pressure was elevated. Two of the fetuses had fetal hydrops, which suggested severe right heart dysfunction. All fetuses were delivered by emergent cesarean delivery. After birth, all the infants developed persistent pulmonary hypertension and required oxygen inhalation. Of these, three required mechanical ventilation, and two, nitric oxide inhalation. All infants improved within 2 weeks, and they had no neurological and cardiac complications after discharge. Conclusion. Right heart dilatation and severe tricuspid regurgitation in the absence of a cardiac defect in the fetus strongly suggested ductal dysfunction. Careful evaluation of ductal patency and right ventricular function can lead to precise early diagnosis and good prognosis. - 北野 良博; 奥山 宏臣; 臼井 規朗; 森川 信行; 増本 幸二; 高安 肇; 中村 知夫; 石川 浩史; 川滝 元良; 林 聡; 稲村 昇; 野瀬 恵介; 左合 治彦日本周産期・新生児医学会雑誌 = Journal of Japan Society of Perinatal and Neonatal Medicine 46 4 1123 - 1126 (一社)日本周産期・新生児医学会 2010年12月2002年1月〜2007年12月に出生した、胎児横隔膜ヘルニア(CDH)と出生前に診断された、単胎である、当該疾患以外の重篤な胎児奇形(染色体異常、致命的な心疾患)がない、出生直後からgentle ventilationによる呼吸管理を含む集中治療が行われた各調査実施5施設で出生した新生児を対象に、後方視的に検討し、治療成績を明らかにして、出生前評価から予後不良群を予測する可否を検討した。調査の結果、117例の登録が得られた。病変は左109例、右6例、両側2例で、左CDHのみを対象にした。全体の治療成績は90日生存87例(79.8%)、退院81例(74.3%)、合併症なき退院71例(65.1%)であった。胃が左胸腔から右胸腔にまで脱出している症例が34.9%もあったことは予想外で、胃泡の右胸腔内脱出が左横隔膜ヘルニアではまれでないことが判明した。約半数が帝王切開で娩出され、殆どの症例で高頻度人工換気(HFO)が使用されていた。NO吸入療法も80%の症例で使用されていた。ECMOは16例(15%)の症例で施行されていた。横隔膜の修復には約半数の症例で人口布が使用されていた。肝脱出の有無、胃の位置、LHRが有意なリスク因子であった。肝脱出のない群の90日生存率と合併症なき退院率はそれぞれ95.7%、87.0%と良好であった。肝脱出群の予後を左右する因子としては胃の位置の方がLHRより強力であることが示唆された。
- 石川 浩史; 川滝 元良; 左合 治彦; 北野 良博; 林 聡; 中村 知夫; 高安 肇; 森川 信行; 臼井 規朗; 稲村 昇; 野瀬 恵介; 奥山 宏臣; 増本 幸二日本周産期・新生児医学会雑誌 = Journal of Japan Society of Perinatal and Neonatal Medicine 46 4 1070 - 1072 2010年12月2001年1月〜2007年12月に研究班参加5施設で在胎36週以降に出生した先天性横隔膜ヘルニア(CDH)110例について後方視的に検討した。また、出生直後からgentle ventilationによる呼吸管理を含む集中治療が行われた症例を分娩方針により2群に分類し、予定帝王切開(帝切)群46例と予定経腟分娩群64例に分け両群の背景、胎児超音波所見および出生前治療内容について検討した。在胎週数は予定帝切群で僅かに早い傾向を認めた。出生体重、男女比については有意差を認めなかった。胎児超音波所見では重症度の指標とされるL/T比は有意差を認めなかったが、LHR(肝臓が胸腔内に脱出する所見(liver up所見))を伴うものの頻度、胃胞が胸腔内で半分以上患側に偏位するものの頻度は予定帝切群で多かった。両群の新生児予後については、主評価項目である生後90日の生存、合併症なき退院については両群間で有意差を認めなかったが、予定帝切群でより新生児予後が不良の傾向を認めた。それ以外の副評価項目では両群間に有意差を認めなかった。予定帝切群では新生児予後がより不良との結果と同時に胎児超音波所見で重症度が高いと予想される症例が多かった。
- 稲村 昇; 北野 良博; 奥山 宏臣; 斎藤 真梨; 臼井 規朗; 森川 信行; 増本 幸二; 高安 肇; 中村 知夫; 石川 浩史; 川滝 元良; 林 聡; 野瀬 恵介; 左合 治彦日本周産期・新生児医学会雑誌 = Journal of Japan Society of Perinatal and Neonatal Medicine 46 4 1131 - 1134 2010年12月
- 奥山 宏臣; 北野 良博; 斉藤 真梨; 臼井 規朗; 森川 信行; 増本 幸二; 高安 肇; 中村 知夫; 石川 浩史; 川滝 元良; 林 聡; 稲村 昇; 野瀬 恵介; 左合 治彦日本周産期・新生児医学会雑誌 = Journal of Japan Society of Perinatal and Neonatal Medicine 46 4 1138 - 1142 (一社)日本周産期・新生児医学会 2010年12月2002年〜2007年の6年間に国立成育医療研究センター、神奈川県立こども医療センター、大阪大学医学部附属病院、大阪府立母子保健総合医療センター、九州大学病院の5施設で出生し、出生前診断された先天性横隔膜ヘルニア(CDH)117例について後方視的に検討した。最初に出生前診断された在胎週数は29(17〜40)週で、24例に羊水過多を認めた。出生週数は38週(28〜42)週、出生体重は2.78(1.04〜4.04)kgで分娩方法は経腟55例、帝王切開62例であった。高頻度人工換気(HFO)は116例(99%)、一酸化窒素(NO)は94例(80%)に、膜型人工肺体外酸循環(ECMO)は19例(16%)に使用され90日生存7例で合併症なしで退院は2例であった。平均気道内圧(MAP)最高値は14(12〜15)cmH2Oで、病変部位は左109、右6、両側2であった。全症例の生存曲線は生後90日でほぼプラトーに達し、90日生存は92例(78.6%)、そのうち4例は90日以降に入院死、2例はそれぞれ18ヵ月、24ヵ月で生存入院中である。これら6例を除く86例(73.5%)が生存退院し、うち12例は退院時に重篤な合併症を伴っていた。退院時に合併症を認めた12例中、1.5歳および3歳時に身体発育遅延または精神・運動発達遅延を認めた割合はそれぞれ80%、71%であった。一方合併症なし退院例のそれぞれの割合は44%、27%と合併症あり退院例に比べ有意に低かった。
- Hitoshi Horigome; Masami Nagashima; Naokata Sumitomo; Masao Yoshinaga; Hiroya Ushinohama; Mari Iwamoto; Junko Shiono; Koh Ichihashi; Satoshi Hasegawa; Tadahiro Yoshikawa; Tamotsu Matsunaga; Hiroko Goto; Kenji Waki; Masaki Arima; Hisashi Takasugi; Yasuhiko Tanaka; Nobuo Tauchi; Masanobu Ikoma; Noboru Inamura; Hideto Takahashi; Wataru Shimizu; Minoru HorieCIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY 3 1 10 - 17 2010年02月 [査読有り]
Background-Data on the clinical presentation and genotype-phenotype correlation of patients with congenital long-QT syndrome (LQTS) diagnosed at perinatal through infantile period are limited. A nationwide survey was conducted to characterize how LQTS detected during those periods is different from that in childhood or adolescence. Methods and Results-Using questionnaires, 58 cases were registered from 33 institutions. Diagnosis (or suspicion) of LQTS was made during fetal life (n = 18), the neonatal period (n = 31, 18 of them at 0 to 2 days of life), and beyond the neonatal period (n = 9). Clinical presentation of LQTS included sinus bradycardia (n = 37), ventricular tachycardia/torsades de pointes (n = 27), atrioventricular block (n = 23), family history of LQTS (n = 21), sudden cardiac death/aborted cardiac arrest (n = 14), convulsion (n = 5), syncope (n = 5), and others. Genetic testing was available in 41 (71%) cases, and the genotype was confirmed in 29 (71%) cases, consisting of LQT1 (n = 11), LQT2 (n = 11), LQT3 (n = 6), and LQT8 (n = 1). Ventricular tachycardia/torsades de pointes and atrioventricular block were almost exclusively observed in patients with LQT2, LQT3, and LQT8, as well as in those with no known mutation. In LQT1 patients, clues to diagnosis were mostly sinus bradycardia or family history of LQTS. Sudden cardiac death/aborted cardiac arrest (n = 14) was noted in 4 cases with no known mutations as well as in 4 genotyped cases, although the remaining 6 did not undergo genotyping. Their subsequent clinical course after aborted cardiac arrest was favorable with administration of beta-blockers and mexiletine and with pacemaker implantation/implantable cardioverter-defibrillator. Conclusions-Patients with LQTS who showed life-threatening arrhythmias at perinatal periods were mostly those with LQT2, LQT3, or no known mutations. Independent of the genotype, aggressive intervention resulted in effective suppression of arrhythmias, with only 7 deaths recorded. (Circ Arrhythm Electrophysiol. 2010; 3: 10-17.) - George Hayashi; Noboru Inamura; Futoshi Kayatani; Yukiko Kawazu; Yuuji HamamichiFETAL DIAGNOSIS AND THERAPY 27 2 97 - 100 2010年 [査読有り]
We report the first case of prenatally diagnosed aortopulmonary window (APW) with interrupted aortic arch. The mother was referred for fetal echocardiography at 29 weeks' gestation because of suspected congenital heart disease. On the short-axis view, we clearly imaged the aortopulmo nary septal defect at the proximal pulmonary artery and type A interrupted aortic arch. The window was 4 mm and the shunt flow detected by color flow Doppler was right-to-left in systole and early diastole. All aortic arch branches originated from the aorta proximal to the interruption. The well-developed ascending aorta was not continuous with the descending aorta in the sagittal view of the aortic arch. Visualization of the direction of the shunt flow across the APW and each origin of subclavian arteries was useful for the diagnosis of APW with interrupted aortic arch. Copyright (C) 2009 S. Karger AG, Basel - 臼井 規朗; 奥山 宏臣; 澤井 利夫; 鎌田 振吉; 福澤 正洋; 窪田 昭男; 金川 武司; 木村 正; 稲村 昇; 濱中 拓郎; 末原 則幸日本周産期・新生児医学会雑誌 = Journal of Japan Society of Perinatal and Neonatal Medicine 44 4 1059 - 1063 2008年12月
- 胎児動脈管早期閉鎖の1例石田 秀和; 稲村 昇; 河津 由紀子; 濱道 裕二; 萱谷 太大阪府立母子保健総合医療センター雑誌 24 1 13 - 16 (地独)大阪府立病院機構大阪母子医療センター 2008年09月母体は32歳、潰瘍性大腸炎に対しmesalazine,prednisoloneを内服していた。36週1日の健診にて、胎児の心拡大と三尖弁逆流を指摘され、翌日、胎児心エコーにて動脈管早期閉鎖と診断、緊急帝王切開となった。出生後の心エコーで肺高血圧を認め、推定右室圧は70mmHgであった。人工呼吸管理行い、一酸化窒素の投与も開始した。肺血圧は次第に低下し日齢5に一酸化窒素を中止し、日齢8に抜管できた。日齢11の心エコーでは肺高血圧を認めず退院となった。その後の心機能は問題なく精神運動発達も正常である。(著者抄録)
- Yukiko Kawazu; Noboru Inamura; Futoshi KayataniCIRCULATION JOURNAL 72 9 1471 - 1475 2008年09月 [査読有り]
Background The therapeutic strategy for pulmonary atresia (PA) and severe pulmonary stenosis (PS) with intact ventricular septum is controversial. Recent improvements in prenatal detection necessitate the identification of predictors of outcome for appropriate counseling and prenatal management planning. Methods and Results Echocardiograms of 18 fetuses antenatally diagnosed with PA (n=14) and PS (n=4) were reviewed and the total cardiac dimension (TCD) and tricuspid valve diameter (TVD) were measured. The right ventricular end-diastolic volume (RVEDV) was calculated from the right ventriculogram of the neonatal period by the percentage of the predicted normal value (%RVEDV). There was a positive correlation between TVD/TCD and %RVEDV (p < 0.001). As the initial treatment, balloon atrioseptostomy was performed in 13 cases of TVD/TCD < 0.26. As the final treatment, patients with TVD/TCD < 0.17 underwent or were planned for the Fontan procedure. Patients with TVD/TCD > 0.21 underwent or were planned for biventricular repair. Patients whose TVD/TCD was between 0.17 and 0.21 underwent or were planned for 1.5 ventricular repairs. Conclusion TVD/TCD is a useful index for selecting the postnatal initial treatment for PA/PS and to predict the final status of the fetus. Prenatal detection and prediction of the future status is helpful for family counseling Furthermore, it will help to decide the postnatal management prenatally. - 石田 秀和; 稲村 昇; 青木 寿明; 河津 由紀子; 北 知子; 萱谷 太; 斎藤 哲也; 石丸 和彦; 盤井 成光; 川田 博昭; 岸本 英文日本小児循環器学会雑誌 24 1 64 - 64 (NPO)日本小児循環器学会 2008年01月
- 石田 秀和; 稲村 昇; 青木 寿明; 河津 由紀子; 北 知子; 萱谷 太; 斎藤 哲也; 石丸 和彦; 盤井 成光; 川田 博昭; 岸本 英文; 芳本 潤; 中村 好秀日本小児循環器学会雑誌 24 1 65 - 65 (NPO)日本小児循環器学会 2008年01月
- 青木 寿明; 稲村 昇; 石田 秀和; 河津 由紀子; 北 知子; 萱谷 太; 斎藤 哲也; 石丸 和彦; 盤井 成光; 川田 博昭; 岸本 英文日本小児循環器学会雑誌 24 1 67 - 67 (NPO)日本小児循環器学会 2008年01月
- 石丸 和彦; 岸本 英文; 川田 博昭; 盤井 成光; 齊藤 哲也; 萱谷 太; 稲村 昇; 北 知子; 河津 由紀子; 青木 寿明; 石田 秀和日本小児循環器学会雑誌 24 1 68 - 68 (NPO)日本小児循環器学会 2008年01月
- 齊藤 哲也; 岸本 英文; 川田 博昭; 盤井 成光; 石丸 和彦; 萱谷 太; 稲村 昇; 北 知子; 河津 由紀子; 青木 寿明; 石田 秀和日本小児循環器学会雑誌 24 1 68 - 68 (NPO)日本小児循環器学会 2008年01月
- 高度房室弁逆流を伴う多脾症候群に2段式肺動脈絞扼術と経皮的バルーン血管形成術を行った1例青木 寿明; 稲村 昇; 石田 秀和; 河津 由紀子; 北 知子; 萱谷 太; 盤井 成光; 川田 博昭; 岸本 英文大阪府立母子保健総合医療センター雑誌 23 1 52 - 57 (地独)大阪府立病院機構大阪母子医療センター 2007年11月高度房室弁逆流を伴う多脾症候群に、2段式肺動脈絞扼術と経皮的バルーン血管形成術を行った事例(1歳2ヵ月・女児)を報告した。高度房室弁逆流に対して7ヵ月時にグレン手術、2段式肺動脈絞扼術を、1歳2ヵ月時にチアノーゼの改善と肺動静脈瘻の予防を目的に、絞扼部に対して経皮的バルーン血管形成術を行った。治療後、房室弁逆流の増加を認めず、フォンタン手術の待機中である。
- 上野 豪久; 窪田 昭男; 稲村 昇; 川原 央好; 長谷川 利路; 奥山 宏臣日本周産期・新生児医学会雑誌 43 2 572 - 572 (一社)日本周産期・新生児医学会 2007年06月
- 石田 秀和; 稲村 昇; 青木 寿明; 河津 由紀子; 北 知子; 萱谷 太; 齋藤 哲也; 石丸 和彦; 磐井 成光; 川田 博昭; 岸本 英文日本小児循環器学会雑誌 23 3 254 - 254 (NPO)日本小児循環器学会 2007年05月
- 青木 寿明; 稲村 昇; 石田 秀和; 河津 由紀子; 北 知子; 萱谷 太; 岸本 英文日本小児循環器学会雑誌 23 3 270 - 270 (NPO)日本小児循環器学会 2007年05月
- 盤井 成光; 岸本 英文; 川田 博昭; 石丸 和彦; 齋藤 哲也; 萱谷 太; 稲村 昇; 北 知子; 河津 由紀子; 青木 寿明; 石田 秀和日本小児循環器学会雑誌 23 3 282 - 282 (NPO)日本小児循環器学会 2007年05月
- 青木 寿明; 稲村 昇; 石田 秀和; 河津 由紀子; 北 知子; 萱谷 太日本小児循環器学会雑誌 23 3 323 - 323 (NPO)日本小児循環器学会 2007年05月
- 川田 博昭; 岸本 英文; 盤井 成光; 石丸 和彦; 齋藤 哲也; 萱谷 太; 稲村 昇; 北 知子; 河津 由紀子; 青木 寿明; 石田 秀和日本小児循環器学会雑誌 23 3 325 - 325 (NPO)日本小児循環器学会 2007年05月
- 石丸 和彦; 岸本 英文; 川田 博昭; 盤井 成光; 齋藤 哲也; 萱谷 太; 稲村 昇; 北 知子; 河津 由紀子; 青木 寿明; 石田 秀和日本小児循環器学会雑誌 23 3 327 - 327 (NPO)日本小児循環器学会 2007年05月
- 先天性心疾患児におけるパリビズマブ投与の検討 ガイドラインの適正な運用を目指して北 知子; 萱谷 太; 稲村 昇; 河津 由紀子; 青木 寿明; 石田 秀和; 中島 徹日本小児科学会雑誌 111 2 305 - 305 (公社)日本小児科学会 2007年02月
- 心室-大血管の再建術 DKS手術 Damus-Kaye-Stansel手術後の心室機能および半月弁機能の検討盤井 成光; 岸本 英文; 川田 博昭; 石丸 和彦; 齋藤 哲也; 萱谷 太; 稲村 昇; 北 知子; 河津 由紀子; 青木 寿明; 石田 秀和日本心臓血管外科学会雑誌 36 Suppl. 152 - 152 (NPO)日本心臓血管外科学会 2007年01月
- 心室-大血管の再建術 右室流出路再建 二心室修復を施行した純型肺動脈閉鎖、重症肺動脈弁狭窄症例の遠隔期QOLの規定因子川田 博昭; 岸本 英文; 盤井 成光; 石丸 和彦; 齊藤 哲也; 萱谷 太; 稲村 昇; 北 知子; 河津 由紀子; 青木 寿明; 石田 秀和日本心臓血管外科学会雑誌 36 Suppl. 167 - 167 (NPO)日本心臓血管外科学会 2007年01月
- 川田 博昭; 岸本 英文; 盤井 成光; 石丸 和彦; 斎藤 哲也; 萱谷 太; 稲村 昇; 北 知子; 角 由紀子; 青木 寿明; 石田 秀和The Japanese Journal of THORACIC AND CARDIOVASCULAR SURGERY 54 Suppl. 354 - 354 シュプリンガー・ジャパン(株) 2006年09月
- M Takeuchi; M Nakayama; Y Kuwae; K Hamana; N Inamura; N SueharaAMERICAN JOURNAL OF PERINATOLOGY 23 2 89 - 92 2006年02月 [査読有り]
We describe the clinical course and autopsy findings of a female fetus with hydrops fetalis due to a huge pericardial rhabdomyoma. Fetal echocardiography at 21 weeks gestation demonstrated a huge tumor in the left ventricle. The fetus died of hydrops fetalis due to cardiac dysfunction at 24 weeks gestation. Autopsy demonstrated that the tumor protruded from the epicardial region of the apex into the pericardial cavity and induced a hypoplastic left ventricle and lung. Microscopically, the cardiac tumor showed characteristics of rhabdomyoma. This localization of cardiac rhabdomyoma is rare, but we remain aware of the possibility of an unusual and rapid progression of cardiac rhabdomyoma. - M Iida; N Inamura; M TakeuchiCIRCULATION JOURNAL 70 1 147 - 149 2006年01月 [査読有り]
Newborn case of maternal anti-SSA antibody-induced congenital complete heart block (CCHB) accompanying cardiomyopathy is presented. Unexpectedly, she died of ventricular tachycardia, not bradycardia, 6 days after birth. Autopsy revealed left ventricular cardiomyopathy with endocardial fibroelastosis. Thus, when evaluating fetal cardiac performance in cases of maternal anti-SSA antibody-induced CCHB, it is necessary to pay attention to myocardial attributes such as endocardial hyperplasia. - N Inamura; A Kubota; T Nakajima; F Kayatani; H Okuyama; T Oue; H KawaharaJOURNAL OF PEDIATRIC SURGERY 40 8 1315 - 1319 2005年08月 [査読有り]
Purpose: The prognosis of antenatally diagnosed congenital diaphragmatic hernia (ADCDH) is still very poor despite of innovation of various therapeutics. The authors reviewed their new therapeutic strategy of ADCDH from a viewpoint of cardiologic function. Methods: The cardiac function in 19 cases of ADCDH was reviewed. The patients, at the age of 0 days, were divided into 2 groups, PG (+) and PG (-), according to the requirement of prostaglandin El (PGE(1)) to attenuate pulmonary hypertension. The left ventricular (LV) end-diastolic dimension (LV diastolic diameter index [LVDI]) and bilateral pulmonary arterial diameters (total pulmonary artery index [TPAI]) were measured on days 0 and 2. Result: Only I patient died of cardiac or respiratory failure, and the survivors' postoperative course was uneventful. Eleven patients needed inhalation of nitric oxide (NO), and in 9 of those, PGE(1) was administered. The LVDI and TPAI of day 0 in PG (+) were significantly smaller than those in PG (-) and the controls. The LVDI increased from postnatal day 0 to day 2 in both PG (+) and PG (-). Although the LV was too small to output enough volume, the right ventricle successfully compensated for the low output through the ductus arteriosus, kept patent by NO and PGE(1). Conclusion: For ADCDH with sever pulmonary hypertension, keeping patent ductus arteriosus with NO and PGEI plays a critical role in obtaining excellent clinical outcome. Thus, the authors proposed a new therapeutic strategy for ADCDH based on a circulatory management. (c) 2005 Elsevier Inc. All rights reserved. - N Inamura; Y Kado; T Nakajima; F KayataniAMERICAN JOURNAL OF PERINATOLOGY 22 4 199 - 204 2005年05月 [査読有り]
Tetralogy of Fallot with absent pulmonary valve (TOF/APV) is a rare form of congenital heart disease with a high risk of perinatal mortality, particularly when diagnosed before birth. We aimed to assess whether global left and right ventricular function in fetal TOF/APV, using the Tei index, correlate with outcome. We reviewed the fetal echocardiogram and clinical outcome of eight fetuses diagnosed with TOF/APV. Of the eight cases, four developed cardiovascular compromise, leading to intrauterine death in two fetuses and neonatal demise in two fetuses, and four fetuses survived the neonatal period. The right ventricular (RV) Tei index was significantly greater and the left ventricular (LV) Tei index tended to be greater in nonsurvivors compared with survivors with TOF/APV (RV Tel, 0.90 +/- 0.17 versus 0.30 +/- 0.28, p < 0.05; LV Tei, 0.97 +/- 0.42 versus 0.54 +/- 0.21). The global LV and RV function can be affected in TOF/APV. Furthermore, more severe pulmonary insufficiency and worse biventricular function as assessed by Tei index likely contribute to the high perinatal mortality associated with this disease. - N Inamura; M Taketazu; JF Smallhorn; LK HornbergerAMERICAN JOURNAL OF PERINATOLOGY 22 2 91 - 97 2005年02月 [査読有り]
We sought to determine whether left ventricular (LV) function is abnormal in a fetus with severe tricuspid valve disease (TVD), and whether it may contribute to the outcome. We measured the LV Tei index (including isovolumic relaxation [IRT], contraction, and ejection times) in 31 fetuses with TVD, compared the data with measurements from 32 normal fetuses, and correlated these measurements with pulmonary morphology and outcome. LV Tei index was significantly greater, ejection times shorter, and IRT longer in TVD compared with controls. The Tei index was highest in fetuses with either pulmonary insufficiency or atresia compared with those with forward flow. Finally, LV Tei index was significantly greater in fetuses with fetal (n = 5) or neonatal (n = 9) demise than in neonatal survivors (n = 7). Global LV performance as assessed by the Tei index is abnormal in TVD and likely contribute to the high mortality associated with TVD. - N Inamura; T Nakajima; F Kayatani; H KawataCIRCULATION JOURNAL 68 12 1227 - 1229 2004年12月 [査読有り]
Transcatheter coil embolization for coronary artery to left ventricular fistula was successfully performed in a neonate. At 30 weeks' gestation, fetal echocardiography showed a hypoplastic right ventricle with intact ventricular septum, absent pulmonary valve, tricuspid atresia, and marked distension of the right coronary artery. After birth. the neonate had congestive heart failure and the electrocardiogram showed myocardial ischemic changes in the left ventricular area. Aortography showed a dilated right coronary artery arising from the ascending aorta and draining into the left ventricle. Transcatheter coil embolization was carried out on the 9th day after birth. Since the procedure, no myocardial ischemic changes have been detected. Transcatheter coil embolization is a useful therapy for coronary artery fistula associated with myocardial ischemia. - N Inamura; T Nakajima; F Kayatani; H Kawata; M TakeuchiPEDIATRICS INTERNATIONAL 45 4 481 - 483 2003年08月 [査読有り]
- 稲村 昇; 松下 享; 福並 正剛; 佐野 哲也; 竹内 真; 黒飛 俊二; 三浦 拓也; 松田 暉; 岡田 伸太郎Journal of cardiology 39 2 101 - 107 2002年02月Objectives. Supraventricular arrhythmias are one of the most common and fatal sequelae of the Fontan operation. P wave triggered signal averaged electrocardiography was performed in patients undergoing the Fontan operation to evaluate the presence of atrial degeneration, and to clarify which factors affected the development of atrial arrhythmias. Methods. P wave triggered signal averaged electrocardiography was recorded in 14 patients after the Fontan-type operation (conventional atriopulmonary connection in 5 and total cavopulmonary connection in 9) and 15 healthy controls. The duration and area of the filtered P wave, and the signal magnitudes (M20, M30)at 20 Hz and 30 Hz obtained from the frequency domain analysis of the P wave(M20, M30) were evaluated and compared with the hemodynamic data. Results. The duration and area of the filtered P wave, M20 and M30 in patients after atriopulmonary connection were significantly greater than in those after total cavopulmonary connection and the control subjects (p < 0.05). M20 was significantly greater in patients after total cavopulmonary connection than in the control subjects. Right atrial volume in patients after atriopulmonary connection was significantly (p < 0.001) larger than in patients after total cavopulmonary connection (p < 0.05). There were no significant differences in other indices including atrial pressure between the two groups. Conclusions. Our results suggest that the substrate for atrial arrhythmias such as atrial myocardial degeneration and fibrosis is frequently present in patients after the Fontan operation, especially after atriopulmonary connection. Thus, the enlarged right atrium may be involved in the presence of a substrate for atrial arrhythmias. The developmental risk for late atrial arrhythmias seems to be present even in patients after total cavopulmonary connection.
- N Inamura; T Nakajima; H Kawata; H KishimotoPEDIATRIC CARDIOLOGY 23 1 106 - 107 2002年01月 [査読有り]
- Y Kawahira; H Kishimoto; H Kawata; S Ikawa; H Ueda; T Nakajima; F Kayatani; N Inamura; T MoriJOURNAL OF CARDIAC SURGERY 14 4 259 - 265 1999年07月 [査読有り]
Background:Operative survival after the Fontan procedure is good; however, there are some patients with disappointing results, especially those with atrial isomerism. Objectives: We tested whether the diameter of the pulmonary veins, which is reported as a useful indicator of pulmonary blood flow, predicts operative results after the Fontan operation. Patients and Methods: We evaluated 30 consecutive patients undergoing either the bidirectional Glenn anastomosis (BDG) or the Fontan operation. Age at operation ranged from 3 to 81 months (mean 30). Diagnosis was right or left isomeric heart in 15 patients, double-outlet right ventricle in 4 and various other malformations in 11. BDG was performed in 16 patients and the Fontan operation in 14 patients. The diameters of the pulmonary veins were measured proximal to the entrance into the atrium in the late phase of a pulmonary arteriogram. The pulmonary vein (PV) index (in mm(2)/m(2)) was calculated from the sum of the cross-sectional areas of these veins divided by the body surface area. Results: Of the patients undergoing BDG (+/- ancillary procedures), 12 had successful results and 4 had unsuccessful results. The PV index for hemodynamically successful patients was 361 +/- 153 and 275 +/- 60 mm2/m2 (mean +/- SD) for unsuccessful patients (p = 0.30). Of the patients who underwent the Fontan operation, 13 had successful and 1 had unsuccessful results. The PV index for successful patients was >285 mm(2)/m(2) and 137 mm(2)/m(2) for the nonsuccessful patients. The new pulmonary vascular resistance (PVR) calculated by using the PV index (mean pressure difference between the pulmonary artery and the atrium/PV index) for BDG patients with successful or unsuccessful results was 2.0 +/- 0.5 or 3.5 +/- 0.2 mmHg/mm(2) per m(2), respectively (p < 0.01). The new PVR for Fontan patients with successful results was <2.0 mmHg/mm(2) per m(2), while that for the patient with an unsuccessful result was 4.4. The new PVR completely separated patients into successful and unsuccessful groups, while conventionally calculated PVR did not (p = 0.63). Conclusions: PV index appears to be a useful morphological indicator of pulmonary blood flow and "new" PVR may improve the decision-making strategy for patients presenting with univentricular heart, especially those associated with isomeric heart. - H Kawata; H Kishimoto; S Ikawa; T Ueno; T Nakajima; F Kayatani; N Inamura; T NakadaCARDIOLOGY IN THE YOUNG 8 3 290 - 294 1998年07月 [査読有り]
Hepatic venous blood has been thought to play some role as a vasoactive agent in the development of pulmonary arteriovenous fistulas in patients with congenital heart disease. During the last 15 years, we have observed pulmonary arteriovenous fistulas in 3, and systemic arteriovenous fistulas in 2, patients from our 16 cases of left isomerism. During the same period, neither pulmonary nor systemic arteriovenous fistulas were detected among 50 patients with right isomerism. Pulmonary arteriovenous fistulas had developed in the absence of surgery in I of the patients. Both pulmonary and systemic fistulas were detected in an another patient, in whom the hepatic venous blood bypassed the pulmonary circulation. The level of somatostatin, which is known to reduce splanchnic blood flow was high in the systemic venous blood of this patient. Although the mechanism of development of the fistulas has yet to be clarified, we should be aware that not only pulmonary, but also systemic arteriovenous fistulas can be found in patients with left isomerism, even prior to any surgical intervention. - Y Kawahira; H Kishimoto; H Kawata; S Ikawa; H Ueda; T Nakajima; F Kayatani; N Inamura; T NakadaJOURNAL OF CARDIAC SURGERY 12 4 253 - 260 1997年07月 [査読有り]
Objectives: This study was done to clarify which diameter, that of the pulmonary arteries (PAs) or that of the pulmonary veins (PVs), more precisely reflects pulmonary blood flow (PBF) bilaterally and unilaterally. Methods: To evaluate bilateral PBF, we studied 15 consecutive patients with Kawasaki disease as normal patients and 30 patients with tetralogy of Fallot who received cardiac catheterization. To evaluate unilateral PBF, 20 patients with various congenital heart diseases undergoing cineangiography and lung perfusion scintigraphy were studied. The diameter of PA was measured immediately proximal to the origin of the first lobar branches bilaterally, and right PA area, left PA area, PA area (mm(2)), and PA index (mm(2)/m(2)) were calculated. The diameter of PV was also measured distal to the junction with the left atrium. Right PV area, left PV area, PV area (mm(2)), and PV index (mm(2)/m(2)) were calculated from these diameters. Pulmonary blood flow (PBF) was obtained by the Pick method during catheterization. To evaluate unilateral PBF, PBF was divided into right and left PBF according to the right/left perfusion ratio measured by lung perufusion scintigraphy. Results: Evaluation of bilateral PBF was as follows: in normal patients, PA and PV areas were correlated with body surface area (r = 0.88, p = 0.0001 and r = 0.93, p = 0.0001); PA index and PV index ranged from 248 to 436 (mean = 343) mm(2)/m(2) and from 346 to 595 (mean = 466) mm(2)/m(2), respectively, and were constant irrespective of body surface area; PA and PV areas were correlated with PBF in normal patients, as well as in patients with tetralogy of Fallot. There was a better correlation between PV area and PBF than between PA area and PBF in normal patients, as well as a significantly better correlation in patients with tetralogy of Fallot. Evaluation of unilateral PBF was as follows: right PV area was correlated with right PBF (p = 0.0002), while right PA area was not; left PV area and left PA area were correlated with left PBF; right/left PV area ratio was correlated with the right/left perfusion ratio with better agreement than right/left PA area ratio. Conclusion: Our data suggest that the size of PVs in patients with congenital heart disease may be more useful than the size of PAs to indicate bilateral and unilateral PBF than the size of PAs. Differences in PV area of each lung may be a suitable indicator of discrepancy in blood flow to each lung. - Y Kawahira; H Kishimoto; H Kawata; S Ikawa; H Ueda; T Nakajima; F Kayatani; N Inamura; T NakadaPEDIATRIC CARDIOLOGY 18 2 107 - 111 1997年03月 [査読有り]
The objective of the study was to examine the relation between the morphology of the common atrioventricular valve and regurgitation of the valve in patients with right atrial isomerism, We examined seven consecutive patients with documented right atrial isomerism who subsequently underwent postmortem examination during a 10-year period. The degree of regurgitation and the diameters of the common valve were evaluated via cineangiography, and the site of regurgitation was evaluated by echocardiography. The morphology of the common atrioventricular valve was assessed further at autopsy. Cineangiography revealed valve diameters ranging from 14.8 to 27.8 mm (mean 20.9 mm). Valvar regurgitation was revealed within 2 months of birth in all patients. Regurgitation abruptly worsened in three patients after placement of a Blalock-Taussig shunt or a central shunt and postintubation. Autopsies revealed that the common atrioventricular valve consisted of four leaflets in five patients, and three leaflets in two. The anterior leaflets were large and protruding in all patients, and the lateral leaflets were thickened in six, All patients had a mass consisting of the left lateral leaflets and chordae with direct attachment of the chordae to the ventricular muscle (the right lateral leaflet was attached to the ventricular muscle and immobile in one patient). The lateral leaflets clung to the ventricular wall and exhibited poor movement in six patients, Leaflets with poor mobility corresponded to the regurgitant valvar site as assessed by echocardiography in six patients; and the regurgitation in three patients with acute deterioration occurred at the valvar side with poor mobility. It is concluded that the common atrioventricular valve in patients with right atrial isomerism has morphologic characteristics that may be associated with valvar regurgitation and malignant potential for abrupt deterioration after replacement of systemic-pulmonary shunting. - H Kawata; H Kishimoto; T Ueno; T Nakajima; N Inamura; T NakadaANNALS OF THORACIC SURGERY 62 6 1843 - 1845 1996年12月 [査読有り]
Although transaortic patch repair under cardiopulmonary bypass is a suitable procedure for aortopulmonary window, another method without cardiopulmonary bypass may be the only one for an infant with extremely low birth weight. We describe a successful repair of an infant with extremely low birth weight (758 g) by closing the window with a clip through a left thoracotomy. Cardiac catheterization 7 months after the operation showed no residual shunt and no stenosis of ascending aorta, pulmonary artery, or coronary arteries in the patient, whom we believe to be one of the smallest with successful repair. - Youichi Kawahira; Hidefumi Kishimoto; Hiroaki Kawata; Seiichiro Ikawa; Hideki Ueda; Takayoshi Ueno; Tohru Nakajima; Futoshi Kayatani; Noboru Inamura; Takashi Miwatani; Takeshi NakadaThe American Journal of Cardiology 76 12 979 - 982 1995年11月These findings suggest that PA banding may be suitable in children with congenital heart disease and excessive pulmonary flow, and that best results are obtained when the band circumference is < 90% of the standard pulmonary valve-ring circumference, as calculated from an equation derived from normal pulmonary valve dimensions. This guideline applies equally well to small infants weighing < 3 kg and to larger patients. © 1995.
- Y. Kawahira; H. Kishimoto; M. Iio; S. Ikawa; H. Ueda; T. Maeno; F. Kayatani; N. Inamura; T. Nakada[Zasshi] [Journal]. Nihon Kyōbu Geka Gakkai 42 7 1003 - 1006 1994年Surgical treatment for a hypoplastic aortic arch associated with coarctation or interruption of the aorta is controversial. We evaluate the changes of diameter of proximal transverse aortic arch after surgery in 28 patients. Proximal transverse aortic arch in all patients was preoperatively 3.5 +/- 0.9 mm (2.5 to 7 mm), and 54 +/- 12% (36 to 84%) to the normal aortic valve dimension (n-AVD: 16.6 X BSA0.6). While postoperative proximal transverse aortic arch was 6.5 +/- 1.8 mm, and 76 +/- 12% to the n-AVD, and significantly grew more than the preoperative arch dimension (p = 0.0001). In 18 patients having two times cardiac catheterization postoperatively, proximal transverse aortic arch was 6.5 +/- 1.6 mm, and 75 +/- 13% to n-AVD on the 1st postoperative examination. On the 2nd examination, the arch was 9.9 +/- 1.9 mm, and 88 +/- 12% to n-AVD, and significantly grew with increasing years (p < or = 0.0003). We concluded that the proximal transverse aortic arch, which was more than 36% to n-AVD in diameter, if not dilated surgically, grew with increasing years after aortic arch repair.
- 飯尾 雅彦; 宮本 勝彦; 黒田 修; 中川 正; 稲村 昇; 松田 暉日本心臓血管外科学会雑誌 20 9 1524 - 1527 The Japanese Society for Cardiovascular Surgery 1991年生後31日目の総肺静脈還流異常症Darling分類1-A型症例に対する根治手術後に人工心肺からの離脱が困難な左心不全をきたした.垂直静脈を開放することにより人工心肺からの離脱および閉胸が可能となった.術後3日目に垂直静脈に通していた糸を引き上げることにより垂直静脈の経皮的二期的閉鎖を行った.閉鎖前後において左房圧,体動脈圧に変化はなく術後経過は良好であった.垂直静脈の経皮的二期的閉鎖は本症の術後左心不全に対する有用な一手段と考えられたので報告する.
- Youichi Kawahira; Hidefumi Kishimoto; Hiroaki Kawata; Seiichro Ikawa; Hideki Ueda; Tohru Nakajima; Futoshi Kayatani; Noboru Inamura; Toru MoriEchocardiography 2 4 259 - 265 1985年 [査読有り]
Abstract Background:Operative survival after the Fontan procedure is good however, there are some patients with disappointing results, especially those with atrial isomerism. Objectives: We tested whether the diameter of the pulmonary veins, which is reported as a useful indicator of pulmonary blood flow, predicts operative results after the Fontan operation. Patients and Methods: We evaluated 30 consecutive patients undergoing either the bidirectional Glenn anastomosis (BDG) or the Fontan operation. Age at operation ranged from 3 to 81 months (mean 30). Diagnosis was right or left isomeric heart in 15 patients, double‐outlet right ventricle in 4 and various other malformations in 11. BDG was performed in 16 patients and the Fontan operation in 14 patients. The diameters of the pulmonary veins were measured proximal to the entrance into the atrium in the late phase of a pulmonary arteriogram. The pulmonary vein (PV) index (in mm2/m2) was calculated from the sum of the cross‐sectional areas of these veins divided by the body surface area. Results: Of the patients undergoing BDG (± ancillary procedures), 12 had successful results and 4 had unsuccessful results. The PV index for hemodynamically successful patients was 361 ± 153 and 275 ± 60 mm2/m2 (mean 5 SD) for unsuccessful patients (p = 0.30). Of the patients who underwent the Fontan operation, 13 had successful and 1 had unsuccessful results. The PV index for successful patients was > 285 mm2/m2 and 137 mm2/m2 for the nonsuccessful patients. The new pulmonary vascular resistance (PVR) calculated by using the PV index (mean pressure difference between the pulmonary artery and the atrium/PV index) for BDG patients with successful or unsuccessful results was 2.0 ± 0.5 or 3.5 ± 0.2 mmHg/mm2 per m2, respectively (p < 0.01). The new PVR for Fontan patients with successful results was < 2.0 mmHg/mm2 per m2, while that for the patient with an unsuccessful result was 4.4. The new PVR completely separated patients into successful and unsuccessful groups, while conventionally calculated PVR did not (p = 0.63). Conclusions: PV index appears to be a useful morphological indicator of pulmonary blood flow and “new” PVR may improve the decision‐making strategy for patients presenting with univentricular heart, especially those associated with isomeric heart. Copyright © 1985, Wiley Blackwell. All rights reserved
MISC
- 萩原 智; 上嶋 一臣; 西田 直生志; 依田 広; 三長 孝輔; 南 康範; 田北 雅弘; 青木 智子; 盛田 真弘; 千品 寛和; 松原 卓哉; 大丸 直哉; 稲村 昇; 工藤 正俊 肝臓 64 (11) 567 -574 2023年11月
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- 真菌性感染性心内膜炎によるバルサルバ洞破裂の1例西 孝輔; 稲村 昇; 草野 信義; 今岡 のり; 丸谷 怜; 杉本 圭相; 小田 晋一郎 日本小児循環器学会総会・学術集会抄録集 59回 [II -07] 2023年07月
- 「CDH難治例手術の要点と盲点(重症症例・合併症症例の対応と胸腔鏡手技の実際)」 胸腔鏡下先天性横隔膜ヘルニア手術の開腹移行と再発例についての検討矢本 真也; 照井 慶太; 永田 公二; 岡崎 任晴; 豊島 勝昭; 稲村 昇; 佐藤 義朗; 丸山 秀彦; 横井 暁子; 増本 幸二; 矢崎 悠太; 小池 勇樹; 奥山 宏臣; 臼井 規朗 日本周産期・新生児医学会雑誌 59 (Suppl.1) P120 -P120 2023年06月
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- 先天性横隔膜ヘルニアの胎児期循環器パラメータの推移と予後との関連性矢本 真也; 照井 慶太; 豊島 勝昭; 稲村 昇; 岡崎 任晴; 永田 公二; 早川 昌弘; 奥山 宏臣; 甘利 昭一郎; 横井 暁子; 増本 幸二; 小池 勇樹; 矢崎 悠太; 臼井 規朗 日本周産期・新生児医学会雑誌 59 (Suppl.1) P271 -P271 2023年06月
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- 外科医療におけるビッグデータの有効活用 希少難治性疾患におけるビッグデータを用いたエビデンス創出 日本先天性横隔膜ヘルニア研究グループ(JCDHSG)と国際共同研究の比較近藤 琢也; 永田 公二; 照井 慶太; 奥山 宏臣; 甘利 昭一郎; 稲村 昇; 小池 勇樹; 矢本 真也; 岡崎 任晴; 矢崎 悠太; 金森 豊; 豊島 勝昭; 早川 昌弘; 古川 泰三; 増本 幸二; 横井 暁子; 臼井 規朗; 田尻 達郎 日本外科学会定期学術集会抄録集 123回 PD -8 2023年04月
- 重症先天性横隔膜ヘルニアにおける胎児鏡下気管閉塞術の適応と診療ガイドライン掲載に向けた今後の課題永田 公二; 近藤 琢也; 照井 慶太; 矢本 真也; 増本 幸二; 甘利 昭一郎; 金森 豊; 岡崎 任晴; 矢崎 悠太; 豊島 勝昭; 小池 勇樹; 金 聖和; 横井 暁子; 稲村 昇; 早川 昌弘; 臼井 規朗; 奥山 宏臣; 田尻 達郎 日本外科学会定期学術集会抄録集 123回 DP -1 2023年04月
- STIC法による胎児心臓遠隔診断稲村 昇; 高田 のり 超音波医学 50 (Suppl.) S669 -S669 2023年04月
- Spatiotemporal image correlation(STIC)による胎児心臓遠隔診断の有用性と課題点今岡 のり; 稲村 昇 日本小児科学会雑誌 127 (2) 220 -220 2023年02月
- 冠動脈瘤を伴った冠動脈瘻の一例 病理学的検討も含めて草野 信義; 丸谷 怜; 西 孝輔; 今岡 のり; 石丸 和彦; 佐藤 隆夫; 杉本 圭相; 稲村 昇 日本小児科学会雑誌 127 (2) 377 -377 2023年02月
- レベルII胎児心臓超音波検査オンライン多施設間全国登録について瀧聞 浄宏; 池田 智明; 武井 黄太; 加地 剛; 河津 由紀子; 川崎 有希子; 稲村 昇; 日本胎児心臓病学会総務委員会 日本小児循環器学会総会・学術集会抄録集 58回 [I -04] 2022年07月
- ECMOで改善しない肺高血圧を呈した大動脈縮窄合併の1男児例今岡 のり; 丸谷 怜; 益海 英樹; 草野 信義; 上嶋 和史; 杉本 圭相; 夫 律子; 稲村 昇 日本小児循環器学会総会・学術集会抄録集 58回 [I -10] 2022年07月
- 15歳以上で川崎病と診断した3症例草野 信義; 丸谷 怜; 益海 英樹; 西 孝輔; 上嶋 和史; 高田 のり; 稲村 昇 日本小児循環器学会総会・学術集会抄録集 58回 [II -08] 2022年07月
- 胎児心エコー検査ガイドライン改定を今後の診療に活かすために 胎児心エコー検査ガイドライン改定のポイントと活用方法稲村 昇; 堀米 仁志; 瀧聞 浄宏; 渋谷 和彦; 与田 仁志; 河津 由紀子; 廣野 恵一 日本小児循環器学会総会・学術集会抄録集 58回 [I -01] 2022年07月
- レベルII胎児心臓超音波検査オンライン多施設間全国登録について瀧聞 浄宏; 池田 智明; 武井 黄太; 加地 剛; 河津 由紀子; 川崎 有希子; 稲村 昇; 日本胎児心臓病学会総務委員会 日本小児循環器学会総会・学術集会抄録集 58回 [I -04] 2022年07月
- ECMOで改善しない肺高血圧を呈した大動脈縮窄合併の1男児例今岡 のり; 丸谷 怜; 益海 英樹; 草野 信義; 上嶋 和史; 杉本 圭相; 夫 律子; 稲村 昇 日本小児循環器学会総会・学術集会抄録集 58回 [I -10] 2022年07月
- 15歳以上で川崎病と診断した3症例草野 信義; 丸谷 怜; 益海 英樹; 西 孝輔; 上嶋 和史; 高田 のり; 稲村 昇 日本小児循環器学会総会・学術集会抄録集 58回 [II -08] 2022年07月
- Masumi Hideki; Marutani Satoshi; Kusano Nobuyoshi; Uesima Kazushi; Takada Nori; Sugimoto Keisuke; Inamura Noboru; Mizutani Kazuki Acta Medica Kinki University 47 (1) 5 -10 2022年06月
- 丸谷 怜; 西 孝輔; 上嶋 和史; 高田 のり; 西野 貴子; 城 玲央奈; 中松 清志; 法里 慧; 杉本 圭相; 稲村 昇 日本成人先天性心疾患学会雑誌 11 (2) 24 -28 2022年05月
- 集学的治療を要した子宮体癌を合併したEbstein病成人例丸谷 怜; 西 孝輔; 上嶋 和史; 高田 のり; 西野 貴子; 城 玲央奈; 中松 清志; 法里 慧; 杉本 圭相; 稲村 昇 日本成人先天性心疾患学会雑誌 11 (2) 24 -28 2022年05月
- 産婦人科における3D-4D超音波の役割 Spatiotemporal image correlation法による胎児心臓遠隔診断の有用性と課題点今岡 のり; 稲村 昇 超音波医学 49 (Suppl.) S346 -S346 2022年04月
- 総肺静脈還流異常症を疑いスクリーニングし,その後三心房心と診断された1例松原 弥生; 稲村 昇; 高田 のり; 藤田 富雄 超音波医学 49 (Suppl.) S757 -S757 2022年04月
- STIC法による胎児心臓遠隔診断稲村 昇; 高田 のり 超音波医学 49 (Suppl.) S760 -S760 2022年04月
- 小林 聡; 中谷 弥生; 猪飼 央子; 鍵谷 雅彦; 稲村 幹夫 臨床眼科 76 (4) 457 -462 2022年04月
- 近藤 琢也; 永田 公二; 奥山 宏臣; 早川 昌弘; 豊島 勝昭; 甘利 昭一郎; 照井 慶太; 古川 泰三; 臼井 規朗; 増本 幸二; 稲村 昇; 岡崎 任晴; 岡和田 学; 矢本 真也; 内田 恵一; 横井 暁子; 田尻 達郎 日本小児外科学会雑誌 58 (3) 431 -431 2022年04月
- 河野 淳; 永田 公二; 照井 慶太; 甘利 昭一郎; 稲村 昇; 小池 勇樹; 漆原 直人; 岡崎 任晴; 矢崎 悠太; 奥山 宏臣; 金森 豊; 豊島 勝昭; 早川 昌弘; 古川 泰三; 増本 幸二; 横井 暁子; 臼井 規朗; 田尻 達郎 日本小児外科学会雑誌 58 (3) 447 -447 2022年04月
- 永田 公二; 照井 慶太; 近藤 琢也; 増本 幸二; 甘利 昭一郎; 金森 豊; 矢本 真也; 岡崎 任晴; 矢崎 悠太; 豊島 勝昭; 小池 勇樹; 古川 泰三; 横井 暁子; 稲村 昇; 早川 昌弘; 臼井 規朗; 奥山 宏臣; 田尻 達郎 日本小児外科学会雑誌 58 (3) 535 -535 2022年04月
- 正畠 和典; 矢本 真也; 梅田 聡; 藤井 誠; 白石 真之; 永田 公二; 照井 慶太; 早川 昌弘; 甘利 昭一郎; 増本 幸二; 岡崎 任晴; 稲村 昇; 漆原 直人; 豊島 勝昭; 内田 恵一; 古川 泰三; 岡和田 学; 横井 暁子; 田附 裕子; 奥山 宏臣; 臼井 規朗 日本小児外科学会雑誌 58 (3) 536 -536 2022年04月
- 産婦人科における3D-4D超音波の役割 Spatiotemporal image correlation法による胎児心臓遠隔診断の有用性と課題点今岡 のり; 稲村 昇 超音波医学 49 (Suppl.) S346 -S346 2022年04月
- 総肺静脈還流異常症を疑いスクリーニングし,その後三心房心と診断された1例松原 弥生; 稲村 昇; 高田 のり; 藤田 富雄 超音波医学 49 (Suppl.) S757 -S757 2022年04月
- STIC法による胎児心臓遠隔診断稲村 昇; 高田 のり 超音波医学 49 (Suppl.) S760 -S760 2022年04月
- 稲村 昇 超音波医学 49 (2) 119 -128 2022年03月
- 第5咽頭弓動脈遺残に第4咽頭弓動脈離断を合併した大動脈縮窄の4歳児例草野 信義; 丸谷 怜; 益海 英樹; 上嶋 和史; 高田 のり; 西野 貴子; 前西 修; 稲村 昇 日本小児科学会雑誌 126 (2) 355 -355 2022年02月
- 心雑音の可視化による無害性心雑音の診断稲村 昇; 丸谷 怜; 河津 由起子; 高田 のり 日本小児科学会雑誌 126 (2) 390 -390 2022年02月
- 三心房心の胎児診断例高田 のり; 稲村 昇; 益海 英樹; 草野 信義; 上嶋 和史; 丸谷 怜; 杉本 圭相 日本小児科学会雑誌 126 (2) 420 -420 2022年02月
- MEFV遺伝子変異を伴った難治性neutrophilic urticariaの1例稲村 衣美; 藤田 靖幸; 須貝 達朗; 冨田 智子; 清水 聡子 市立札幌病院医誌 81 (1) 53 -58 2022年01月
- AMPLATZERTM Duct Occluder IIを用いた動脈管開存に対するカテーテル治療の経験益海 英樹; 丸谷 怜; 草野 信義; 上嶋 和史; 高田 のり; 杉本 圭相; 稲村 昇; 水谷 一輝 大阪小児科学会誌 38 (4) 11 -11 2021年12月
- 上嶋 和史; 丸谷 怜; 西 孝輔; 高田 のり; 杉本 圭相; 稲村 昇 日本小児循環器学会雑誌 37 (4) 307 -311 2021年12月
- 飯島 紅祐; 山田 久美子; 和田 恭直; 稲村 昌輝; 北村 典子; 井垣 歩; 小柴 賢洋 医学検査 70 (3) 583 -587 2021年07月
- レベルII胎児心エコー検査のオンライン多施設間全国登録について瀧聞 浄宏; 池田 智明; 武井 黄太; 加地 剛; 河津 由紀子; 川崎 有希子; 稲村 昇; 日本胎児心臓病学会総務委員会 日本小児循環器学会総会・学術集会抄録集 57回 [OR4 -2] 2021年07月
- ACTA2遺伝子に変異を認めた若年性大動脈解離の1例丸谷 怜; 西 孝輔; 益海 英樹; 高田 のり; 上嶋 和史; 西野 貴子; 稲村 昇 日本小児循環器学会総会・学術集会抄録集 57回 [P5 -2] 2021年07月
- 稀なcircular shuntを呈した胎児肺動脈弁欠損症候群の1例高田 のり; 稲村 昇; 丸谷 怜; 杉本 圭相 日本小児循環器学会総会・学術集会抄録集 57回 [P6 -6] 2021年07月
- 罹患後2ヵ月で心筋梗塞を発症した川崎病巨大冠動脈瘤の1幼児例草野 信義; 西 孝輔; 上嶋 和史; 高田 のり; 丸谷 怜; 稲村 昇; 藤崎 拓也; 松尾 久実代; 高橋 邦彦; 萱谷 太 日本小児循環器学会総会・学術集会抄録集 57回 [P44 -9] 2021年07月
- 佐藤 一正; 平田 悠; 稲村 衣美; 山口 泰之; 古屋 和彦; 畑中 一映 臨床皮膚科 75 (7) 485 -490 2021年06月
- 照井 慶太; 古川 泰三; 永田 公二; 早川 昌弘; 奥山 宏臣; 甘利 昭一郎; 横井 暁子; 増本 幸二; 矢本 真也; 岡崎 任晴; 稲村 昇; 豊島 勝昭; 内田 恵一; 岡和田 学; 臼井 規朗; 日本CDH研究グループ 日本小児外科学会雑誌 57 (2) 326 -326 2021年04月
- 若年型大動脈解離の1例丸谷 怜; 西 孝輔; 益海 英樹; 高田 のり; 有馬 智之; 上嶋 和史; 稲村 昇 日本小児科学会雑誌 125 (2) 209 -209 2021年02月
- 稀なcircular shuntを呈した肺動脈弁欠損症候群の胎児診断例稲村 昇; 高田 のり; 丸谷 怜; 上嶋 和史; 西 孝輔 日本小児科学会雑誌 125 (2) 318 -318 2021年02月
- ST上昇型心筋梗塞を有する院外心停止患者の1年後の死亡率と神経学的転帰(Mortality and Neurological Outcome at 1-year in Out-of-hospital Cardiac Arrest Patients with ST-segment Elevation Myocardial Infarction)矢野 弘崇; 新田 義一; 松田 隼治; 田村 洋平; 成田 岳; 加藤 駿一; 高野 寿一; 池ノ内 孝; 村田 和也; 狩野 実希; 高宮 智正; 稲村 幸洋; 根木 謙; 佐藤 明; 大和 恒博; 稲葉 理; 松村 穣 日本心血管インターベンション治療学会抄録集 29回 1109 -1109 2021年02月
- ST上昇を伴わない院外心停止患者の1年後の死亡率と神経学的転帰(Mortality and Neurological Outcome at 1-year in Out-of-hospital Cardiac Arrest Patients without ST-segment Elevation)田村 洋平; 新田 義一; 松田 隼治; 成田 岳; 矢野 弘崇; 加藤 駿一; 高野 寿一; 池ノ内 孝; 村田 和也; 羽田 泰晃; 狩野 実希; 高宮 智正; 稲村 幸洋; 根木 謙; 佐藤 明; 大和 恒博; 稲葉 理; 松村 穣 日本心血管インターベンション治療学会抄録集 29回 1113 -1113 2021年02月
- Takada Nori; Marutani Satoshi; Ueshima Kazushi; Nishi Kousuke; Sugimoto Keisuke; Inamura Noboru Journal of Pediatric Cardiology and Cardiac Surgery 5 (1) 7 -11 2021年
- Nishi Kosuke; Marutani Satoshi; Takada Nori; Ueshima Kazushi; Sugimoto Keisuke; Inamura Noboru Acta Medica Kinki University 45 (2) 39 -46 2020年12月
- 妊娠12-20週胎児心筋における24分割Sphericity index(SI)とFractional shortening(FS)町田 めぐみ; 夫 律子; 中村 貴子; 上西 功太郎; 稲村 昇 超音波医学 47 (Suppl.) S172 -S172 2020年11月
- 改訂版 胎児心エコー検査ガイドラインの紹介 推奨する根拠について石井 陽一郎; 金 基成; 川崎 有希; 永田 弾; 漢 伸彦; 高橋 美穂; 稲村 昇; 日本胎児心臓病学会CQ班 超音波医学 47 (Suppl.) S362 -S362 2020年11月
- 胎児心臓病学「胎児治療へつなぐ先天性心疾患の胎児診断」 胎児重症三尖弁閉鎖不全症例の胎児期治療適応症例の層別化の可能性石井 陽一郎; 稲村 昇; 橋本 和久; 森 雅啓; 廣瀬 将樹; 松尾 久実代; 青木 寿明; 高橋 邦彦; 萱谷 太 日本小児循環器学会雑誌 36 (Suppl.2) s2 -142 2020年11月
- 日本における多施設胎児心エコー検査登録の分析(The analysis of multicenter fetal echocardiography registration in Japan)瀧聞 浄宏; 池田 智明; 武井 黄太; 加地 剛; 河津 由紀子; 川崎 有希子; 稲村 昇; 日本胎児心臓病学会総務委員会 日本小児循環器学会雑誌 36 (Suppl.2) s2 -199 2020年11月
- 小心臓症候群患児におけるMRIを用いた心機能評価の検討西 孝輔; 稲村 昇; 丸谷 怜; 杉本 圭相 日本小児循環器学会雑誌 36 (Suppl.2) s2 -256 2020年11月
- 稲村 昇 産婦人科の実際 69 (12) 1325 -1327 2020年11月
- 稲村 昇 産婦人科の実際 69 (12) 1328 -1330 2020年11月
- 山下 雄平; 丸谷 怜; 西 孝輔; 上嶋 和史; 高田 のり; 西野 貴子; 杉本 圭相; 稲村 昇 日本小児循環器学会雑誌 36 (3) 252 -255 2020年10月
- 稲村 和俊; 松井 祐興; 伊藤 吏; 窪田 俊憲; 欠畑 誠治 Audiology Japan 63 (4) 234 -241 2020年08月
- 稲村 昇 周産期医学 50 (7) 1059 -1063 2020年07月
- 小林 聡; 稲村 幹夫; 鍵谷 雅彦; 田岡 梨奈; 猪飼 央子 あたらしい眼科 37 (7) 865 -868 2020年07月
- 草野 信義; 稲村 昇; 西 孝輔; 上嶋 和史; 高田 のり; 丸谷 怜; 西野 貴子 心臓 52 (3) 338 -343 2020年03月
- 稲村 昇 日本臨床 別冊 (循環器症候群IV) 375 -377 2020年03月
- 小心臓症候群患児に対するMRIを用いた心機能評価の検討西 孝輔; 稲村 昇; 丸谷 怜; 杉本 圭相 日本小児科学会雑誌 124 (2) 328 -328 2020年02月
- 膜様部中隔瘤による右室流出路狭窄を呈した心室中隔欠損の一例山下 雄平; 稲村 昇; 丸谷 怜; 西 孝輔; 上嶋 和史; 高田 のり; 西野 貴子; 坂口 元一; 杉本 圭相 日本小児科学会雑誌 124 (2) 435 -435 2020年02月
- 小心臓症候群患児に対するMRIを用いた心機能評価の検討西 孝輔; 稲村 昇; 丸谷 怜; 杉本 圭相 日本小児科学会雑誌 124 (2) 328 -328 2020年02月
- 肺動脈の瘤状変化を来したファロー四徴術後の成人例丸谷 怜; 高田 のり; 西 孝輔; 上嶋 和史; 西野 貴子; 稲村 昇 日本成人先天性心疾患学会雑誌 9 (1) 252 -252 2020年01月
- 腹水貯留で発見された集学的治療を要した子宮体癌とEbstein病の成人例丸谷 怜; 高田 のり; 西 孝輔; 上嶋 和史; 稲村 昇 日本成人先天性心疾患学会雑誌 9 (1) 256 -256 2020年01月
- 上嶋 和史; 丸谷 怜; 高田 のり; 岡野 意浩; 宮崎 紘平; 竹村 豊; 井庭 慶典; 稲村 昇; 坂田 尚己; 岡田 満; 杉本 圭相 近畿大学医学雑誌 44 (3-4) 19A -19A 2019年12月
- レベルII胎児心臓超音波検査オンライン多施設間全国登録の解析武井 黄太; 池田 智明; 加地 剛; 河津 由紀子; 川崎 有希子; 稲村 昇; 瀧聞 浄宏; 日本胎児心臓病学会総務委員会 日本小児循環器学会雑誌 35 (Suppl.1) s1 -166 2019年06月
- 当院における成人先天性心疾患外来の現状丸谷 怜; 稲村 昇; 高田 のり; 上嶋 和史; 西 孝輔; 杉本 圭相 日本小児循環器学会雑誌 35 (Suppl.1) s1 -243 2019年06月
- MRIと心エコーによるPR評価の検討西 孝輔; 稲村 昇; 丸谷 怜; 杉本 圭相 日本小児循環器学会雑誌 35 (Suppl.1) s1 -326 2019年06月
- 胎児重複大動脈弓7例の検討高田 のり; 稲村 昇; 西 孝輔; 上嶋 和史; 丸谷 怜; 塩野 展子; 杉本 圭相 日本小児循環器学会雑誌 35 (Suppl.1) s1 -346 2019年06月
- 9歳発症の冠攣縮性狭心症の男児例上嶋 和史; 稲村 昇; 丸谷 怜; 高田 のり; 西 孝輔; 杉本 圭相 日本小児循環器学会雑誌 35 (Suppl.1) s1 -406 2019年06月
- 冬木 真規子; 奥山 宏臣; 臼井 規朗; 田口 智章; 早川 昌弘; 増本 幸二; 金森 豊; 漆原 直人; 稲村 昇; 横井 暁子; 岡崎 任晴; 豊島 勝昭; 古川 泰三; 照井 慶太; 内田 恵一; AMED難治性疾患実用化研究事業「先天性横隔膜ヘルニアにおける最適な人工換気法・手術時期・手術方法に関する研究」 日本周産期・新生児医学会雑誌 55 (2) 468 -468 2019年06月
- 近藤 琢也; 永田 公二; 伊藤 美春; 甘利 昭一郎; 稲村 昇; 内田 恵一; 漆原 直人; 岡崎 任晴; 岡和田 学; 奥山 宏臣; 金森 豊; 照井 慶太; 豊島 勝昭; 早川 昌弘; 古川 泰三; 増本 幸二; 横井 暁子; 臼井 規朗; 田口 智章; 新生児先天性横隔膜ヘルニア研究グループ 日本小児外科学会雑誌 55 (3) 481 -481 2019年05月
- 稲村 昇 心臓 51 (3) 284 -289 2019年03月
- 僧帽弁逆流を契機に発見できなかった左冠動脈口閉鎖症の1女児例高田 のり; 稲村 昇; 西 孝輔; 上嶋 和史; 丸谷 怜; 杉本 圭相 日本小児科学会雑誌 123 (2) 248 -248 2019年02月
- 川崎病冠動脈病変の心エコー分類「A-1」患児における経過観察期間の検討西 孝輔; 丸谷 怜; 稲村 昇; 杉本 圭相 日本小児科学会雑誌 123 (2) 362 -362 2019年02月
- 学校検診で発見された大動脈縮窄症の11歳男児例上嶋 和史; 稲村 昇; 杉本 圭相 日本小児科学会雑誌 123 (2) 412 -412 2019年02月
- Kusano Nobuyoshi; Marutani Satoshi; Nishino Takako; Inamura Noboru Journal of Pediatric Cardiology and Cardiac Surgery 3 (2) 103 -107 2019年
- Masumi Hideki; Takada Nori; Marutani Satoshi; Sugimoto Keisuke; Inamura Noboru Journal of Pediatric Cardiology and Cardiac Surgery 3 (2) 108 -112 2019年
- Takada Nori; Sugimoto Keisuke; Inamura Noboru Acta Medica Kinki University 43 (2) 75 -80 2018年12月
- 稲村 昇 Neonatal Care (2018秋季増刊) 113 -123 2018年09月
- 先天性心疾患を有する新生児が救急車に乗らずにすむ周産期医療の実現稲村 昇 日本小児循環器学会雑誌 34 (Suppl.1) s1 -98 2018年07月
- 胎児治療最前線:薬物治療/カテーテル治療 抗SS-A抗体陽性妊娠のステロイド投与について今岡 のり; 稲村 昇; 藤田 富雄; 夫 律子; 竹村 司 日本小児循環器学会雑誌 34 (Suppl.1) s1 -147 2018年07月
- レベルII胎児心臓超音波検査 オンライン多施設間全国登録について瀧聞 浄宏; 池田 智明; 武井 黄太; 加地 剛; 河津 由紀子; 川崎 有希; 稲村 昇; 日本胎児心臓病学会総務委員会 日本小児循環器学会雑誌 34 (Suppl.1) s1 -245 2018年07月
- 川崎病急性期におけるDWS(Diastolic wall strain)の検討西 孝輔; 稲村 昇; 丸谷 怜; 竹村 司 日本小児循環器学会雑誌 34 (Suppl.1) s1 -290 2018年07月
- diastolic wall strain(DWS)の小児における基準値の検討丸谷 怜; 稲村 昇; 西 孝輔; 竹村 司 日本小児循環器学会雑誌 34 (Suppl.1) s1 -315 2018年07月
- WPW症候群に対するアブレーション術後ATP急速静注による再伝導の誘発上嶋 和史; 中村 好秀; 稲村 昇; 竹村 司 日本小児循環器学会雑誌 34 (Suppl.1) s1 -376 2018年07月
- 小児期左側房室弁置換症例の遠隔期成績西野 貴子; 北山 仁士; 佐賀 俊彦; 篠原 徹; 丸谷 怜; 稲村 昇 日本小児循環器学会雑誌 34 (Suppl.1) s1 -382 2018年07月
- 稲村 昇 超音波検査技術 43 (Suppl.) S70 -S70 2018年06月
- 臼井 規朗; 奥山 宏臣; 照井 慶太; 早川 昌弘; 増本 幸二; 豊島 勝昭; 甘利 昭一郎; 漆原 直人; 稲村 昇; 横井 暁子; 岡崎 任晴; 岡和田 学; 古川 泰三; 内田 恵一; 田口 智章 日本周産期・新生児医学会雑誌 54 (2) 498 -498 2018年06月
- 稲村 昇 産科と婦人科 85 (Suppl) 114 -121 2018年04月
- 稲村 昇 産科と婦人科 85 (1) 31 -37 2018年01月
- 診断および治療方針について討論が必要な胎児心臓病をどのように対応するべきか 異なる経過を辿った胎児診断Critical ASの2例田中 智彦; 稲村 昇; 江見 美杉; 松尾 久実代; 平野 恭悠; 青木 寿明; 高橋 邦彦; 河津 由紀子; 萱谷 太 日本小児循環器学会雑誌 33 (Suppl.1) s1 -148 2017年07月
- Single-source dual-energy CTによる川崎病冠動脈病変の石灰化組成の検討草野 信義; 丸谷 怜; 稲村 昇; 篠原 徹; 竹村 司 日本小児循環器学会雑誌 33 (Suppl.1) s1 -209 2017年07月
- レベルII胎児心臓超音波検査の多施設間全国登録について瀧聞 浄宏; 池田 智明; 武井 黄太; 加地 剛; 河津 由紀子; 稲村 昇; 日本胎児心臓病学会総務委員会 日本小児循環器学会雑誌 33 (Suppl.1) s1 -272 2017年07月
- 稲村 昇 周産期医学 47 (4) 477 -481 2017年04月
- 稲村 昇 日本小児循環器学会雑誌 32 (6) 451 -461 2016年11月
- 完全大血管転位症1型における胎児期超音波所見と出生後経過の検討金 基成; 稲村 昇; 川瀧 元良; 江見 美杉; 河津 由紀子; 上田 秀明 日本小児循環器学会雑誌 32 (Suppl.1) s1 -181 2016年07月
- 本邦の多施設間レベルII胎児心臓超音波検査登録について瀧聞 浄宏; 池田 智明; 武井 黄太; 加地 剛; 河津 由紀子; 稲村 昇; 日本胎児心臓病学会総務委員会 日本小児循環器学会雑誌 32 (Suppl.1) s1 -182 2016年07月
- 胎児診断を受けた完全大血管転位の臨床像江見 美杉; 稲村 昇; 金 基成; 川滝 元良; 河津 由紀子; 上田 秀明 日本小児循環器学会雑誌 32 (Suppl.1) s1 -184 2016年07月
- 先天性心疾患術後の接合部頻拍にはアミオダロン、あるいはニフェカラントか?青木 寿明; 杉辺 英世; 江見 美杉; 松尾 久美代; 田中 智彦; 平野 恭悠; 河津 由紀子; 稲村 昇; 山内 早苗; 盤井 成光; 萱谷 太 日本小児循環器学会雑誌 32 (Suppl.1) s1 -202 2016年07月
- Fontan術後女性の卵巣機能松尾 久実代; 稲村 昇; 杉辺 英世; 江見 美杉; 田中 智彦; 平野 恭悠; 川口 晴菜; 青木 寿明; 河津 由紀子; 萱谷 太 日本小児循環器学会雑誌 32 (Suppl.1) s1 -219 2016年07月
- 同じ心臓の形態異常を有した2組の双胎の例杉辺 英世; 稲村 昇; 江見 美杉; 松尾 久美代; 田中 智彦; 平野 恭悠; 青木 寿明; 河津 由紀子; 萱谷 太 日本小児循環器学会雑誌 32 (Suppl.1) s1 -248 2016年07月
- 胎児頻脈性不整脈に対する経胎盤的抗不整脈薬投与に関する臨床試験 副作用報告(第2報)三好 剛一; 前野 泰樹; 左合 治彦; 稲村 昇; 安河内 聰; 川滝 元良; 堀米 仁志; 与田 仁志; 竹田津 未生; 新居 正基; 生水 真紀夫; 賀藤 均; 白石 公; 坂口 平馬; 上田 恵子; 桂木 真司; 池田 智明 日本小児循環器学会雑誌 32 (Suppl.1) s1 -256 2016年07月
- 胎児診断のピットホール「総肺静脈還流異常」の経験河津 由紀子; 稲村 昇; 杉辺 英世; 江見 美杉; 松尾 久実代; 平野 恭悠; 田中 智彦; 青木 智彦; 萱谷 太 日本小児循環器学会雑誌 32 (Suppl.1) s1 -257 2016年07月
- 出生後左室を胎児期に予測する因子の検討江見 美杉; 稲村 昇; 杉辺 英世; 松尾 久実代; 田中 智彦; 平野 恭悠; 青木 寿明; 河津 由紀子; 萱谷 太 日本小児循環器学会雑誌 32 (Suppl.1) s1 -258 2016年07月
- 胎児診断で単純大動脈縮窄が疑われた16例の検討田中 智彦; 稲村 昇; 杉辺 英世; 江見 美杉; 松尾 久実代; 平野 恭悠; 青木 寿明; 河津 由紀子; 萱谷 太 日本小児循環器学会雑誌 32 (Suppl.1) s1 -259 2016年07月
- Fontan型手術(ec-TCPC)の導管径が心機能や肝機能に及ぼす影響平野 恭悠; 稲村 昇; 杉辺 英世; 江見 美杉; 松尾 久美代; 田中 智彦; 青木 寿明; 河津 由紀子; 萱谷 太 日本小児循環器学会雑誌 32 (Suppl.1) s1 -324 2016年07月
- 当センターにおけるFontan術後死亡例の危険因子河津 由紀子; 稲村 昇; 萱谷 太; 杉辺 英世; 江見 美杉; 松尾 久実代; 平野 恭悠; 田中 智彦; 青木 寿明 日本小児循環器学会雑誌 32 (Suppl.1) s1 -327 2016年07月
- 機能的単心室における房室弁形成術の検討盤井 成光; 川田 博昭; 山内 早苗; 小森 元貴; 富永 佑児; 萱谷 太; 稲村 昇; 河津 由紀子; 青木 寿明 日本小児循環器学会雑誌 32 (Suppl.1) s1 -377 2016年07月
- 大動脈縮窄・大動脈弓離断複合に対する二期的修復術山内 早苗; 盤井 成光; 小森 元貴; 富永 佑児; 萱谷 太; 稲村 昇; 河津 由紀子; 青木 寿明; 川田 博昭 日本小児循環器学会雑誌 32 (Suppl.1) s1 -391 2016年07月
- 小児科に必要な胎児循環生理稲村 昇 大阪小児科学会誌 33 (2) 7 -7 2016年06月
- 稲村 昇 小児外科 48 (5) 481 -487 2016年05月
- 富永佑児; 川田博昭; 盤井成光; 山内早苗; 小森元貴; 萱谷太; 稲村昇; 河津由紀子 日本心臓血管外科学会学術総会(Web) 46th 2016年
- 富永佑児; 川田博昭; 盤井成光; 山内早苗; 小森元貴; 萱谷太; 稲村昇; 河津由紀子; 青木寿明 日本小児循環器学会雑誌 32 (Supplement 1) 2016年
- 河津 由紀子; 稲村 昇; 田中 智彦; 浜道 裕二; 萱谷 太 日本小児循環器学会雑誌 32 (1) 31 -37 2016年01月
- 稲村 昇 日本小児科学会雑誌 = The journal of the Japan Pediatric Society 119 (12) 1695 -1708 2015年12月
- 稲村 昇 Fetal & neonatal medicine 7 (2) 75 -81,46 2015年08月
- 照井慶太; 永田公二; 伊藤美春; 矢本真也; 白石真之; 田口智章; 早川昌弘; 奥山宏臣; 吉田英生; 増本幸二; 金森豊; 五石圭司; 漆原直人; 川瀧元良; 稲村昇; 木村修; 岡崎任晴; 豊島勝昭; 臼井規朗 日本小児外科学会雑誌 51 (3) 456 2015年05月
- 永田公二; 照井慶太; 伊藤美春; 白石真之; 矢本真也; 早川昌弘; 奥山宏臣; 稲村昇; 金森豊; 五石圭司; 田附裕子; 横井暁子; 川瀧元良; 漆原直人; 岡崎任晴; 木村修; 増本幸二; 豊島勝昭; 臼井規朗; 田口智章 日本小児外科学会雑誌 51 (3) 412 -412 2015年05月
- 山内 早苗; 川田 博昭; 盤井 成光; 小森 元貴; 富永 佑児; 萱谷 太; 稲村 昇; 岸本 英文 日本小児循環器学会雑誌 31 (3) 102 -107 2015年05月
- 山内 早苗; 川田 博昭; 盤井 成光; 上仲 永純; 荒木 幹太; 萱谷 太; 稲村 昇; 岸本 英文 日本小児循環器学会雑誌 31 (3) 119 -123 2015年05月
- 稲村 昇 日本小児外科学会雑誌 51 (3) 570 -570 2015年05月
- 稲村 昇 日本小児放射線学会雑誌 31 (1) 8 -13 2015年03月
- 病的新生児の予後2015 先天性心疾患の予後(胎児診断の効果)稲村 昇 日本小児科学会雑誌 119 (2) 209 -209 2015年02月
- 富永佑児; 川田博昭; 盤井成光; 奥田直樹; 小森元貴; 小渡亮介; 萱谷太; 稲村昇; 濱道裕二; 河津由紀子; 岸本英文 日本心臓血管外科学会雑誌 44 (Supplement) 2015年
- 富永佑児; 川田博昭; 盤井成光; 奥田直樹; 小渡亮介; 小森元貴; 萱谷太; 稲村昇; 濱道裕二; 河津由紀子 日本小児循環器学会雑誌 31 (Supplement 1) 2015年
- 小森元貴; 盤井成光; 奥田直樹; 小渡亮介; 富永佑児; 萱谷太; 稲村昇; 濱道裕二; 川田博昭 日本小児循環器学会雑誌 31 (Supplement 1) 2015年
- 金川奈央; 稲村昇; 豊川富子; 田中智彦; 髭野亮太; 濱道裕二; 萱谷太; 阪上美寿々; 富永佑児; 盤井成光 日本Pediatric Interventional Cardiology学会学術集会プログラム抄録集 26th 2015年
- 小渡亮介; 川田博昭; 盤井成光; 奥田直樹; 小森元貴; 富永祐児; 萱谷太; 稲村昇; 濱道裕二; 河津由紀子 日本心臓血管外科学会雑誌 44 (Supplement) 2015年
- 奥田直樹; 川田博昭; 盤井成光; 小森元貴; 小渡亮介; 富永佑児; 萱谷太; 稲村昇; 濱道裕二; 河津由紀子 日本心臓血管外科学会雑誌 44 (Supplement) 2015年
- 稲村 昇 超音波検査技術 39 (6) 591 -592 2014年12月
- 膠原病合併妊婦における52-kDa SSA/Ro p200抗体のavidityならびにIgGサブクラスについての研究宮野 章; 中山 雅弘; 和栗 雅子; 中西 功; 稲村 昇 大阪府立母子保健総合医療センター雑誌 30 (2) 97 -101 2014年12月
- 先天性心疾患の子どもの家族への支援活動 ピアサポートの充実岡山 佳奈; 吉田 佳織; 山本 大輝; 里美 夏菜恵; 大西 加奈子; 田中 はるみ; 河津 由紀子; 稲村 昇; 萱谷 太 大阪府立母子保健総合医療センター雑誌 30 (2) 123 -124 2014年12月
- 塩野 展子; 稲村 昇 小児内科 46 (増刊) 329 -333 2014年11月
- Y. Hamamichi; N. Kanagawa; T. Toyokawa; R. Higeno; T. Tanaka; Y. Kawazu; N. Inamura; F. Kayatani; H. Kawata; H. Kishimoto EUROPEAN HEART JOURNAL 35 238 -238 2014年09月
- Y. Hamamichi; N. Kanagawa; T. Toyokawa; R. Higeno; T. Tanaka; Y. Kawazu; N. Inamura; F. Kayatani; H. Kawata; H. Kishimoto EUROPEAN HEART JOURNAL 35 849 -849 2014年09月
- 先天性疾患の胎児画像診断 今とこれから 先天性心疾患の胎児画像診断稲村 昇 日本小児放射線学会雑誌 30 (Suppl.) 7 -7 2014年06月
- 田附 裕子; 窪田 昭男; 川原 央好; 米田 光宏; 谷 岳人; 稲村 昇; 竹内 宗之; 木内 恵子; 光田 信明; 北島 博之 日本周産期・新生児医学会雑誌 50 (1) 90 -92 2014年05月
- 三好 剛一; 前野 泰樹; 左合 治彦; 稲村 昇; 安河内 聰; 川滝 元良; 堀米 仁志; 与田 仁志; 竹田津 未生; 生水 真紀夫; 新居 正基; 賀藤 均; 萩原 聡子; 尾本 暁子; 白石 公; 坂口 平馬; 西村 邦宏; 上田 恵子; 桂木 真司; 池田 智明 日本周産期・新生児医学会雑誌 50 (1) 136 -138 2014年05月
- 塩野 展子; 稲村 昇; 鳥越 史子; 田中 智彦; 三原 聖子; 成田 淳; 河津 由紀子; 濱道 裕二; 萱谷 太 日本小児循環器学会雑誌 30 (3) 306 -315 2014年05月
- 照井慶太; 永田公二; 臼井規朗; 金森豊; 早川昌弘; 奥山宏臣; 稲村昇; 五石圭司; 増本幸二; 漆原直人; 川滝元良; 木村修; 横井暁子; 田附裕子; 吉田英生; 田口智章 日本小児外科学会雑誌 50 (3) 391 -391 2014年04月
- 稲村 昇 日本医事新報 (4690) 62 -63 2014年03月
- 富永佑児; 川田博昭; 盤井成光; 山内早苗; 小森元貴; 萱谷太; 稲村昇; 濱道裕二; 河津由紀子; 岸本英文 日本小児循環器学会雑誌 30 (Supplement) 2014年
- 小森元貴; 川田博昭; 盤井成光; 山内早苗; 富永佑児; 萱谷太; 稲村昇; 濱道裕二; 河津由紀子; 岸本英文 日本小児循環器学会雑誌 30 (Supplement) 2014年
- 太田 志代; 日高 庸博; 山本 亮; 笹原 淳; 石井 桂介; 米田 光宏; 川原 央好; 窪田 昭男; 稲村 昇; 光田 信明 超音波医学 41 (1) 17 -23 2014年01月
- 盤井 成光; 川田 博昭; 上仲 永純; 山内 早苗; 荒木 幹太; 萱谷 太; 稲村 昇; 岸本 英文 日本小児循環器学会雑誌 30 (2) 147 -152 2014年
- 山下 美智子; 光田 信明; 日高 庸博; 林 周作; 入江 明美; 宮城 晶子; 河津 由紀子; 稲村 昇; 萱谷 太; 石井 桂介 日本小児循環器学会雑誌 30 (2) 166 -172 2014年
- Loeys-Dietz症候群の乳児3例河津 由紀子; 稲村 昇; 石井 良; 萱谷 太; 岡本 伸彦; 望月 成隆; 南條 浩輝; 森崎 裕子 大阪府立母子保健総合医療センター雑誌 29 (1) 49 -56 2013年12月
- 河津 由紀子; 萱谷 太; 稲村 昇 大阪府立母子保健総合医療センター雑誌 29 (1) 113 -114 2013年12月
- 稲村 昇 周産期医学 43 (12) 1587 -1590 2013年12月
- 河津 由紀子; 稲村 昇 小児内科 45 (6) 1120 -1121 2013年06月
- 永田公二; 臼井規朗; 金森豊; 早川昌弘; 奥山博臣; 稲村昇; 中村智夫; 高橋重裕; 増本幸二; 漆原直人; 川滝元良; 木村修; 横井暁子; 照井慶太; 田附裕子; 田口智章 日本小児外科学会雑誌 49 (3) 829 -829 2013年05月
- <治療に活かす>胎児治療の次のステップ 治療適応・術後管理に超音波をどのように応用していくか 胎児頻脈性不整脈胎児診断・治療における超音波の役割稲村 昇 超音波医学 40 (Suppl.) S325 -S325 2013年04月
- 妊娠中期における胎児心臓スクリーニング稲村 昇 超音波医学 40 (Suppl.) S332 -S332 2013年04月
- 盤井 成光; 川田 博昭; 小澤 秀登; 山内 早苗; 金谷 知潤; 萱谷 太; 稲村 昇; 岸本 英文 日本小児循環器学会雑誌 = Acta cardiologica paediatrica Japonica 29 (2) 92 -97 2013年03月
- 河津 由紀子; 岡本 伸彦; 稲村 昇; 石井 良; 南條 浩輝; 望月 成隆; 森崎 裕子; 萱谷 太 日本小児科学会雑誌 117 (1) 122 -128 2013年01月
- Ishii, Y; Inamura, N; Kawazu, Y; Kayatani, F; Arakawa, H ULTRASOUND IN OBSTETRICS & GYNECOLOGY 41 (6) 667 -671 2013年
- 塩野 展子; 河津 由紀子; 稲村 昇; 石井 陽一郎; 萱谷 太; 白石 淳; 北島 博之; 石井 桂介; 光田 信明 日本周産期・新生児医学会雑誌 = Journal of Japan Society of Perinatal and Neonatal Medicine 48 (4) 934 -938 2012年12月
- 稲村 昇 Fetal & neonatal medicine 4 (3) 136 -141,100 2012年12月
- 稲村 昇 周産期医学 42 (10) 1329 -1332 2012年10月
- Y. Hamamichi; J. Narita; Y. Kawazu; N. Inamura; F. Kayatani; H. Kawata; H. Kishimoto EUROPEAN HEART JOURNAL 33 271 -271 2012年08月
- 稲村 昇 日本小児循環器学会雑誌 = Acta cardiologica paediatrica Japonica 28 (4) 230 -232 2012年07月
- 岸本 英文; 川田 博昭; 盤井 成光; 上仲 永純; 山内 早苗; 荒木 幹太; 萱谷 太; 稲村 昇 日本外科学会雑誌 113 (2) 206 -206 2012年03月
- 金森 豊; 臼井 規朗; 田口 智明; 稲村 昇; 奥山 宏臣; 高橋 重裕; 早川 昌弘 日本小児外科学会雑誌 48 (6) 898 -898 2012年
- 伊藤 麻衣; 後藤 真千子; 小杉 恵; 稲村 昇; 窪田 昭男 日本小児外科学会雑誌 48 (1) 161 -161 2012年
- 田附 裕子; 北島 博之; 橘 一也; 竹内 宗之; 木内 恵子; 窪田 昭男; 川原 央好; 米田 光宏; 谷 岳人; 合田 太郎; 梅田 聡; 平野 勝久; 稲村 昇 日本小児外科学会雑誌 48 (6) 897 -898 2012年
- 奥山 宏臣; 臼井 規朗; 藤野 裕士; 田口 智章; 金森 豊; 高橋 繁裕; 早川 昌弘; 稲村 昇 日本小児外科学会雑誌 48 (3) 498 -498 2012年
- 門田 茜; 稲村 昇; 濱道 裕二; 河津 由紀子; 萱谷 太 日本小児循環器学会雑誌 = Acta cardiologica paediatrica Japonica 27 (6) 286 -289 2011年12月
- 河津 由紀子; 稲村 昇; 石井 良; 寺嶋 佳乃; 青木 寿明; 浜道 裕二; 萱谷 太; 盤井 成光; 川田 博昭; 岸本 英文 日本小児循環器学会雑誌 = Acta cardiologica paediatrica Japonica 27 (2) 88 -95 2011年03月
- 石井 良; 稲村 昇; 萱谷 太; 窪田 昭男 日本小児外科学会雑誌 47 (4) 577 -577 2011年
- 高安 肇; 林 聡; 稲村 昇; 野瀬 恵介; 左合 治彦; 北野 良博; 奥山 宏臣; 臼井 規朗; 森川 信行; 増本 幸二; 中村 知夫; 石川 浩史; 川滝 元良 日本小児外科学会雑誌 47 (4) 728 -728 2011年
- 稲村 昇; 萱谷 太; 河津 由紀子; 濱道 裕二; 光田 信明 日本周産期・新生児医学会雑誌 = Journal of Japan Society of Perinatal and Neonatal Medicine 46 (4) 1067 -1069 2010年12月
- 北野 良博; 稲村 昇 日本周産期・新生児医学会雑誌 = Journal of Japan Society of Perinatal and Neonatal Medicine 46 (4) 1121 -1122 2010年12月
- 石井 良; 稲村 昇; 萱谷 太; 窪田 昭男; 光田 信明 日本周産期・新生児医学会雑誌 = Journal of Japan Society of Perinatal and Neonatal Medicine 46 (4) 1143 -1146 2010年12月
- 中田 麻子; 石井 良; 河津 由紀子; 井坂 華奈子; 石井 陽一郎; 寺嶋 佳乃; 高橋 邦彦; 浜道 裕二; 稲村 昇; 萱谷 太; 津田 雅世; 橘 一也; 竹内 宗之; 笹田 真滋; 石川 秀雄 日本小児呼吸器疾患学会雑誌 21 (Suppl.) 96 -96 2010年09月
- 川田 博昭; 岸本 英文; 盤井 成光; 小澤 秀登; 木戸 高志; 萱谷 太; 稲村 昇; 窪田 昭男; 川原 央好 日本外科学会雑誌 111 (2) 127 -127 2010年03月
- 中澤 誠; 西畠 信; 稲村 昇 Fetal & neonatal medicine 2 (1) 4 -13 2010年03月
- 青木 寿明; 稲村 昇; 河津 由紀子; 萱谷 太 日本小児循環器学会雑誌 = Acta cardiologica paediatrica Japonica 26 (2) 99 -105 2010年03月
- 奥山宏臣; 清水義之; 佐々木隆士; 内田薫; 柳原格; 稲村昇 日本周産期・新生児医学会雑誌 46 (2) 2010年
- 奥山 宏臣; 川滝 元良; 林 聡; 稲村 昇; 野瀬 恵介; 左合 治彦; 北野 良博; 斉藤 真梨; 臼井 規朗; 森川 信行; 増本 幸二; 高安 肇; 中村 知夫; 石川 浩史 日本小児外科学会雑誌 46 (3) 556 -556 2010年
- 北野 良博; 川滝 元良; 林 聡; 稲村 昇; 野瀬 恵介; 佐合 治彦; 奥山 宏臣; 斉藤 真梨; 臼井 規朗; 森川 信行; 増本 幸二; 高安 肇; 中村 知夫; 石川 浩史 日本小児外科学会雑誌 46 (3) 557 -557 2010年
- 臼井 規朗; 石川 浩史; 川滝 元良; 稲村 昇; 野瀬 恵介; 佐合 治彦; 北野 良博; 奥山 宏臣; 斉藤 真梨; 森川 信行; 高安 肇; 中村 知夫; 林 聡; 増本 幸二 日本小児外科学会雑誌 46 (3) 557 -557 2010年
- 稲村 昇; 萱谷 太; 北 知子; 河津 由紀子; 川田 博昭; 盤井 成光; 岸本 英文 日本小児循環器学会雑誌 = Acta cardiologica paediatrica Japonica 25 (6) 800 -807 2009年11月
- 稲村 昇; 青木 寿明 産婦人科治療 98 (5) 865 -869 2009年05月
- Kawazu Yukiko; Inamura Noboru; Hamamichi Yuji; Kayatani Futoshi Circulation journal : official journal of the Japanese Circulation Society 73 741 -742 2009年03月
- 稲村昇 小児外科誌 41 481 -485 2009年
- 臼井 規朗; 奥山 宏臣; 澤井 利夫; 福澤 正洋; 窪田 昭男; 金川 武司; 木村 正; 稲村 昇; 濱中 拓郎; 末原 則幸 日本周産期・新生児医学会雑誌 = Journal of Japan Society of Perinatal and Neonatal Medicine 44 (2) 322 -322 2008年06月
- 川田 博昭; 岸本 英文; 盤井 成光; 石丸 和彦; 齊藤 哲也; 萱谷 太; 稲村 昇; 北 知子; 河津 由紀子; 青木 寿明 日本小児循環器学会雑誌 = Acta cardiologica paediatrica Japonica 24 (2) 129 -137 2008年03月
- 稲村 昇; 萱谷 太; 窪田 昭男; 奥山 宏臣; 川原 央好; 長谷川 利路 日本小児外科学会雑誌 44 (4) 648 -649 2008年
- 盤井 成光; 岸本 英文; 川田 博昭; 石丸 和彦; 齊藤 哲也; 萱谷 太; 稲村 昇 日本小児循環器学会雑誌 = Acta cardiologica paediatrica Japonica 24 (1) 53 -58 2008年01月
- Aoki Hisaaki; Inamura Noboru; Ishida Hidekazu; Kawazu Yukiko; Kita Tomoko; Kayatani Futoshi Circulation journal : official journal of the Japanese Circulation Society 71 554 -554 2007年03月
- Kawazu Yukiko; inamura noboru; Kayatani Futoshi; kita tomoko Circulation journal : official journal of the Japanese Circulation Society 71 556 -556 2007年03月
- 稲村 昇 小児科診療 70 (2) 189 -196 2007年02月
- 稲村 昇 日本小児循環器学会雑誌 = Acta cardiologica paediatrica Japonica 23 (1) 4 -13 2007年01月
- 河津 由紀子; 稲村 昇; 萱谷 太; 北 知子; 那須野 明香; 中島 徹 日本小児循環器学会雑誌 = Acta cardiologica paediatrica Japonica 22 (6) 643 -647 2006年11月
- 河津 由紀子; 稲村 昇; 北 知子; 萱谷 太 日本小児科学会雑誌 110 (8) 1122 -1125 2006年08月
- 永田 多恵子; 稲村 昇; 白石 淳; 北島 博之 日本未熟児新生児学会雑誌 = Journal of Japan Society for Premature and Newborn Medicine 18 (2) 71 -74 2006年06月
- N Inamura; Y Kado; T Kita; F Kayatani PEDIATRIC CARDIOLOGY 27 (3) 391 -392 2006年06月
- KADO Y; Inamura Noboru; Kayatani Futoshi; Kita Tomoko Circ J 70 470 -470 2006年
- Y Kado; N Inamura; F Kayatani; T Kita JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 45 (3) 316A -316A 2005年02月
- 稲村昇 日小循誌 21 545 -550 2005年
- 稲村 昇; 窪田 昭男; 川原 央好; 奥山 宏臣; 中井 弘; 萱谷 太; 北 知子 日本小児外科学会雑誌 41 (3) 388 -388 2005年
- 吉田 英樹; 窪田 昭男; 川原 央好; 奥山 宏臣; 中井 弘; 高間 勇一; 稲村 昇 日本小児外科学会雑誌 41 (3) 527 -527 2005年
- 川田 博昭; 岸本 英文; 三浦 拓也; 帆足 孝也; 中島 徹; 萱谷 太; 稲村 昇; 角 由紀子 日本小児循環器学会雑誌 = Acta cardiologica paediatrica Japonica 20 (6) 601 -607 2004年11月
- 三浦 拓也; 角 由紀子; 岸本 英文; 川田 博昭; 帆足 孝也; 塩満 大樹; 中島 徹; 萱谷 太; 稲村 昇; 北 知子 日本小児外科学会雑誌 40 (3) 341 -341 2004年
- 稲村 昇; 中島 徹; 萱谷 太; 窪田 昭男; 田原 央好; 奥山 宏臣; 中井 弘 日本小児外科学会雑誌 40 (6) 753 -753 2004年
- 上田 素子; 稲村 昇; 阪口 理恵; 川井 小百合; 金子 みどり; 清水 啓子; 宮澤 隆博; 太田 剛弘; 中川 昌子 Journal of medical ultrasonics = 超音波医学 30 (6) J719 -J724 2003年11月
- 稲村 昇; 中島 徹; 萱谷 太; 窪田 昭男; 川原 央好; 奥山 宏臣; 大植 孝治 日本小児外科学会雑誌 39 (3) 67 -67 2003年
- N Inamura; J Smallhorn; LK Hornberger JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 39 (5) 414A -414A 2002年03月
- 前畠 慶人; 角由 紀子; 奥山 宏臣; 窪田 昭男; 森 透; 岸本 英文; 川田 博昭; 三浦 拓也; 秦 雅寿; 中島 徹; 萱谷 太; 稲村 昇; 石井 円 日本小児外科学会雑誌 38 (3) 440 -440 2002年
- 小野 正道; 岸本 英文; 川田 博昭; 三浦 拓也; 舩津 俊宏; 盤井 成光; 森 透; 中島 徹; 萱谷 太; 高田 慶応; 稲村 昇; 北 知子 日本小児循環器学会雑誌 = Acta cardiologica paediatrica Japonica 17 (5) 709 -714 2001年12月
- 竹内 真; 中山 雅弘; 稲村 昇; 中島 徹; 川田 博昭; 岸本 英文 日本小児循環器学会雑誌 = Acta cardiologica paediatrica Japonica 17 (4) 542 -547 2001年07月
- 川田 博昭; 稲村 昇; 石井 円; 北島 博之; 森 透; 岸本 英文; 三浦 拓也; 近藤 晴彦; 安政 啓吾; 前畠 慶人; 中島 徹; 萱谷 太; 高田 慶応 日本小児外科学会雑誌 37 (3) 452 -452 2001年
- 奥山 宏臣; 稲村 昇; 窪田 昭男; 大植 孝治; 黒田 征加; 池上 玲一; 神山 雅史; 北村 征治; 木内 恵子; 福光 一夫 日本小児外科学会雑誌 37 (3) 492 -492 2001年
- 三浦 拓也; 稲村 昇; 石井 円; 森 透; 岸本 英文; 川田 博昭; 近藤 晴彦; 安政 啓吾; 前畠 慶人; 中島 徹; 萱谷 太; 高田 慶応 日本小児外科学会雑誌 37 (3) 502 -502 2001年
- 岸本 英文; 稲村 昇; 石井 円; 森 透; 川田 博昭; 三浦 拓也; 近藤 晴彦; 安政 啓吾; 前畠 慶人; 中島 徹; 萱谷 太; 高田 慶応 日本小児外科学会雑誌 37 (3) 509 -509 2001年
- 川田 博昭; 岸本 英文; 三浦 拓也; 盤井 成光; 小野 正道; 近藤 晴彦; 中島 徹; 萱谷 太; 高田 慶応; 稲村 昇; 川上 展弘; 森 透 日本小児循環器学会雑誌 = Acta cardiologica paediatrica Japonica 16 (2) 133 -139 2000年03月
- 岸本 英文; 稲村 昇; 川上 展弘; 森 透; 川田 博昭; 三浦 拓也; 盤井 成光; 近藤 晴彦; 安政 啓吾; 中島 徹; 萱谷 太; 高田 慶応 日本小児外科学会雑誌 36 (3) 107 -107 2000年
- 川田 博昭; 木内 恵子; 福光 一夫; 谷口 晃啓; 井村 賢治; 岸本 英文; 三浦 拓也; 盤井 成光; 森 透; 中島 徹; 萱谷 太; 高田 慶応; 稲村 昇 日本小児外科学会雑誌 35 (6) 818 -819 1999年
- 川田 博昭; 川上 展弘; 森 透; 岸本 英文; 三浦 拓也; 盤井 成光; 近藤 晴彦; 中島 徹; 萱谷 太; 高田 慶応; 稲村 昇 日本小児外科学会雑誌 35 (3) 547 -547 1999年
- 竹内 真; 荒井 洋; 中山 雅弘; 稲村 昇; 中島 徹; 小池 麻子; 飯谷 秀美 日本小児科学会雑誌 102 (11) 1206 -1209 1998年11月
- 岸本 英文; 川田 博昭; 三浦 拓也; 上野 高義; 舩津 俊宏; 盤井 成光; 中島 徹; 萱谷 太; 高田 慶応; 稲村 昇; 北 知子; 中田 健 日本胸部外科学会雑誌 = The Japanese journal of thoracic and cardiovascular surgery 46 138 -139 1998年04月
- 位田 忍; 虫明 聡太郎; 中山 雅弘; 倉橋 浩樹; 高橋 まり; 吉村 文一; 稲村 昇; 田附 裕子; 曹 英樹; 川原 央好; 八木 誠; 井村 賢治 日本小児外科学会雑誌 34 (2) 393 -393 1998年
- 稲村 昇; 中島 徹; 萱谷 太; 高田 慶応; 北 知子 日本小児循環器学会雑誌 = Acta cardiologica paediatrica Japonica 13 (6) 799 -804 1997年12月
- 舩津 俊宏; 稲村 昇; 北 知子; 中田 健; 岸本 英文; 川田 博昭; 三浦 拓也; 上野 高義; 盤井 成光; 中島 徹; 萱谷 太; 高田 慶応 日本小児外科学会雑誌 33 (3) 522 -522 1997年
- 川田 博昭; 稲村 昇; 北 知子; 中田 健; 岸本 英文; 三浦 拓也; 上野 高義; 舩津 俊宏; 盤井 成光; 中島 徹; 萱谷 太; 高田 慶応 日本小児外科学会雑誌 33 (3) 553 -553 1997年
- 稲村 昇; 中島 徹; 萱谷 太; 前野 敏也; 岸本 英文; 川田 博昭; 井川 誠一郎; 川平 洋一; 上田 秀樹; 中田 健 日本小児循環器学会雑誌 = Acta cardiologica paediatrica Japonica 13 (1) 22 -29 1997年01月
- 稲村 昇; 中島 徹; 萱谷 太; 高田 慶応; 北 知子; 岸本 英文; 川田 博昭; 井川 誠一郎; 上野 高義; 西川 正則; 森本 静夫; 中田 健 日本小児循環器学会雑誌 = Acta cardiologica paediatrica Japonica 12 (6) 749 -754 1996年12月
- 藤村 正哲; 川本 豊; 末原 則幸; 井村 賢治; 森本 一良; 島田 憲次; 中島 徹; 稲村 昇; 岸本 英文; 中山 雅弘 日本新生児学会雑誌 32 (1) 19 -25 1996年03月
- 川平 洋一; 岸本 英文; 飯尾 雅彦; 井川 誠一郎; 上田 秀樹; 前野 敏也; 萱谷 太; 稲村 昇; 中田 健 日本心臓血管外科学会雑誌 25 (2) 131 -134 1996年03月
- 岸本 英文; 川田 博昭; 井川 誠一郎; 上野 高義; 中島 徹; 萱谷 太; 稲村 昇; 中田 健 日本小児外科学会雑誌 32 (3) 555 -555 1996年
- 三浦 拓也; 中埜 粛; 島崎 靖久; 加藤 寛; 松田 暉; 稲村 昇; 佐野 哲也 Japanese circulation journal 58 (0) 685 -685 1994年04月
- 井川 誠一郎; 岸本 英文; 飯尾 雅彦; 川平 洋一; 上田 秀樹; 前野 敏也; 萱谷 太; 稲村 昇; 中田 健 日本小児外科学会雑誌 30 (3) 477 -477 1994年
- 川平 洋一; 岸本 英文; 飯尾 雅彦; 井川 誠一郎; 上田 秀樹; 前野 敏也; 萱谷 太; 稲村 昇; 中田 健 日本小児外科学会雑誌 30 (3) 556 -556 1994年
- 滝 悦子; 稲村 昇; 中川 正; 小川 實; 飯尾 雅彦; 黒田 修; 宮本 勝彦 Japanese circulation journal 57 (0) 689 -689 1993年05月
- 小川 實; 稲村 昇; 中川 正; 飯尾 雅彦; 黒田 修; 宮本 勝彦 Japanese circulation journal 57 (0) 690 -690 1993年05月
- 稲村 昇; 中川 正; 小川 實; 飯尾 雅彦; 黒田 修; 宮本 勝彦 Japanese circulation journal 57 (0) 690 -690 1993年05月
- 飯尾 雅彦; 岸本 英文; 井川 誠一郎; 久米 庸一; 川平 洋一; 前野 敏也; 松下 享; 稲村 昇; 中田 建 日本小児外科学会雑誌 29 (3) 548 -548 1993年
- 久米 庸一; 岸本 英文; 飯尾 雅彦; 井川 誠一郎; 川平 洋一; 前野 敏也; 松下 享; 稲村 昇; 中田 健 日本小児外科学会雑誌 29 (3) 562 -562 1993年
- 川平 洋一; 岸本 英文; 飯尾 雅彦; 井川 誠一郎; 久米 庸一; 前野 達也; 松下 享; 稲村 昇; 中田 健 日本小児外科学会雑誌 29 (3) 698 -698 1993年
- 黒田 修; 宮本 勝彦; 飯尾 雅彦; 小川 實; 中川 正; 稲村 昇 Japanese circulation journal 56 (0) 641 -641 1992年05月
- 黒田 修; 宮本 勝彦; 飯尾 雅彦; 田山 雅雄; 小川 實; 中川 正; 稲村 昇 日本小児外科学会雑誌 27 (4) 787 -787 1991年
- 飯尾 雅彦; 宮本 勝彦; 黒田 修; 小川 實; 中川 正; 稲村 昇 日本小児外科学会雑誌 26 (2) 396 -396 1990年
- 宮本 勝彦; 飯尾 雅彦; 黒田 修; 小川 實; 中川 正; 稲村 昇 日本小児外科学会雑誌 26 (2) 458 -458 1990年
- 高野 右嗣; 瀬口 利信; 吉岡 俊昭; 小出 卓出; 中野 悦次; 檜垣 潤; 井村 賢治; 鎌田 振吉; 岡田 正; 中野 敦子; 稲村 昇; 泉 裕; 河 敬世 日本泌尿器科學會雜誌 80 (3) 476 -476 1989年03月
書籍等出版物
- 窪田, 昭男; 奥山, 宏臣 ぱーそん書房 2019年02月 ISBN: 9784907095505 viii, 310, ixp
- 日本新生児成育医学会 メディカ出版 2018年12月 ISBN: 9784840468473 xiii, 849p
- 日本小児循環器学会 診断と治療社 2018年07月 ISBN: 9784787822888 xx, 701p
- 胎児心エコーのすべて稲村 昇 (担当:分担執筆範囲:)2017年02月
- 稲村, 昇 金芳堂 2016年07月 ISBN: 9784765316804 111p
- 胎児心臓病の診断と治療稲村 昇 (担当:分担執筆範囲:)2016年07月
- 先天性心疾患稲村 昇 (担当:分担執筆範囲:)2014年04月
- 系統小児外科稲村 昇 (担当:分担執筆範囲:)2013年03月
- 新生児の臨床検査基準値ディクショナリー稲村 昇 (担当:分担執筆範囲:)2012年07月
講演・口頭発表等
- 12. WPW症候群に対するアブレーション術後ATP急速静注による再伝導の誘発 [通常講演]稲村 昇第22回日本小児心電学会 2017年11月
- 11. ウリナスタチン併用IVIG単回投与変法におけるIVIG必要量の指標に関する検討 [通常講演]稲村 昇第37回日本川崎病学会学術集会 2017年10月
- 10. 遠隔期川崎病冠動脈石灰化病変の体積と遠隔期の患者背景の検討 [通常講演]稲村 昇第37回日本川崎病学会学術集会 2017年10月
- 9. Case report of Ebstein anomaly which dynamic slow-motion display was useful for a diagnosis of the functional pulmonary atresia [通常講演]稲村 昇International Society of Ultrasound in Obstetrics and Gynecology 2017 2017年09月
- 8. Postnatal clinical course of the fetal vascular ring [通常講演]稲村 昇International Society of Ultrasound in Obstetrics and Gynecology 2017 2017年09月
- 7. Analysis of the composition of coronary arterial calcification post-Kawasaki disease with Single-source dual-energy CT [通常講演]稲村 昇6th Scientific Meeting of the World Society for Pediatric and Congenital Heart Surgery 2017年07月
- 6. Long-term results after radiofrequency catheter ablation of Atrioventricular nodal reentrant tachycardia in children [通常講演]稲村 昇6th Scientific Meeting of the World Society for Pediatric and Congenital Heart Surgery 2017年07月
- 5. Dual-energy CTを用いた川崎病後の冠動脈石灰化の組成の検討 [通常講演]稲村 昇第53回日本小児循環器学会学術集会 2017年07月
- 4. 子どもの権利を守るために日頃から色々工夫して行っていること [通常講演]稲村 昇第5回日本子ども療養支援研究会 2017年06月
- 3. 特異な動脈管起始を伴った第5大動脈弓遺残の1例 [通常講演]稲村 昇第120回日本小児科学会 2017年04月
- 2. 冠状動脈狭窄を認めたWilliams症候群の1例 [通常講演]稲村 昇第30回近畿小児科学会 2017年03月
- 1. 当院における10年間の18トリソミー、13トリソミー患児の手術経験 [通常講演]稲村 昇2017年03月
- 胎児心臓スクリーニング [通常講演]稲村 昇国立循環器病研究センター周産期科サマーセミナー 2016年08月
- 胎児循環生理 [通常講演]稲村 昇南大阪医学教育セミナー 2016年08月
- 小児科医に必要な胎児循環生理 [通常講演]稲村 昇大阪小児科学会 2016年06月
- 胎児・新生児の基本断面 [通常講演]稲村 昇阪神心エコー図カンファレンス 2016年04月
所属学協会
共同研究・競争的資金等の研究課題
- 日本学術振興会:科学研究費助成事業 基盤研究(C)研究期間 : 2022年04月 -2025年03月代表者 : 稲村 昇; 丸谷 怜; 石井 陽一郎現代の電子診療録には視覚情報は多いが聴覚情報は少ない。本研究では昔から重要視されていた聴診所見を可視化することで客観的情報として診療録に掲載することで聴診所見を有効に活用することを目指す。方法は先天性心疾患に認める心雑音を電子聴診器でデジタル録音し、音の構成要素(最強点、信号強度、時間、広がり、周波数)を解析する。次に各構成要素と心エコー法で診断する心疾患の重症度との関係を調べ、音の構成要素をsevere, moderate, mild, trivialに序列化する。この序列化した要素をレーダーチャートに組みなおし電子診療録に音源と共に掲載できるようにする。 研究の進め方は【2022年度】心雑音の収集と解析(録音、心エコーによる重症度判定), 【2023年度】心雑音の解析と心エコーの重症度とのマッチング、【2024年度】レーダーチャートの作成である。2023年4月まで、心雑音60名の登録を完了した。登録した内容は、収縮期駆出性雑音48例(肺動脈弁狭窄38例、大動脈弁狭窄10例)、収縮期逆流性雑音6例(僧帽弁逆流)、拡張期逆流性雑音6例(大動脈弁逆流1例、肺動脈弁逆流5例)である。 疾患の程度は、収縮期駆出性雑音がtrivial 2例、mild 23例、moderate 20例、severe3例、収縮期逆流性雑音がmild 5例、moderate 1例、拡張期逆流性雑音がmild 1例、moderate 5例であった。 症例数の多かった収縮期駆出性雑音について心雑音の解析を行い、疾患の程度と比較した。最大RMSはmild -29.9±4.3dB、moderate -30.0±3.4dB、severe -25.6±2.0dB最大周波数はmild 15.6±2.1Hz、moderate 21.9±4.9Hz、severe 28.1±2.0Hzでいずれも統計学的有意差は認めなかった。
- 電子聴診器を使用した心雑音の可視化日本学術振興会:基盤研究C研究期間 : 2019年04月 -2022年03月代表者 : 稲村 昇
- 先天性横隔膜ヘルニアにおける最適な人工換気・手術時期・手術方法に関する研究日本医療研究開発機構:難治性疾患実用化研究事業代表者 : 奥山宏臣