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MIZUKOSHI Atsushi

    Department of Medicine　Lecturer
Last Updated :2024/04/25

Researcher Information

URL

Research funding number

  • 50520318

ORCID ID

J-Global ID

Research Interests

  • Environmental Medicine   hygiene   Risk assessment   Public health   健康影響(14)   室内環境   分析化学   VOC   

Research Areas

  • Life sciences / Hygiene and public health (non-laboratory)
  • Life sciences / Hygiene and public health (laboratory)
  • Environmental science/Agricultural science / Environmental load reduction/restoration technology
  • Environmental science/Agricultural science / Environmental effects of chemicals
  • Environmental science/Agricultural science / Environmental effects of radiation

Academic & Professional Experience

  • 2024/04 - Today  Kindai University Faculty of MedicineDepartment of Preventive Medicine and Behavioral SciencesLecturer
  • 2018/04 - 2024/03  Kindai University Faculty of MedicineDepartment of Environmental Medicine and Behavioral ScienceLecturer
  • 2014/06 - 2019/03  Waseda UniversityInstitute of Applied Brain SciencesVisiting research scholar
  • 2014/04 - 2018/03  Kindai University Faculty of MedicineDepartment of Environmental Medicine and Behavioral ScienceAssistant Professor
  • 2012/04 - 2014/03  Tokyo Metropolitan Industrial Technology Research InstituteResearch and Development Department, Division II , Environment Technology GroupSub-chief Researcher
  • 2011/12 - 2012/03  Tokyo Metropolitan Industrial Technology Research InstituteResearch and Development Department, Division II , Environment Technology GroupResearcher
  • 2007/07 - 2011/11  The University of TokyoGraduate School of Frontier SciencesCollaborative Researcher
  • 2007/07 - 2011/11  Tokyo Metropolitan Industrial Technology Research InstituteDivision of Regional Entities for the Advancement of Technological ExcellenceResearcher

Education

  • 2002/04 - 2007/06  The University of Tokyo  Graduate School of Frontier Sciences  Department of Environment Systems
  • 1998/04 - 2002/03  Tokyo Institute of Technology  工学部  Department of Inorganic Materials

Association Memberships

  • The Society of Heating, Air-Conditioning and Sanitary Engineers of Japan   The Japanese Society for Hygiene   ARCHITECTURAL INSTITUTE OF JAPAN   THE JAPANESE SOCIETY OF CLINICAL ECOLOGY   JAPAN SOCIETY FOR ATMOSPHERIC ENVIRONMENT   SOCIETY OF INDOOR ENVIRONMENT, JAPAN   日本公衆衛生学会   

Published Papers

  • Masayuki Ohyama; Kenichi Azuma; Chika Minejima; Atsushi Mizukoshi; Shuichi Adachi; Norimichi Takenaka
    Journal of Japan Society for Atmospheric Environment 59 (3) 47 - 61 2024/03 [Refereed]
  • Atsushi Mizukoshi; Jiro Okumura; Kenichi Azuma
    Risk Analysis 1 - 17 2023/11 [Refereed]
  • Xi Lu; Sachiko Hojo; Atsushi Mizukoshi; Takahiko Katoh
    BMC Public Health Springer Science and Business Media LLC 23 (1) 2023/06 [Refereed]
     
    Abstract Background In Japan, there are currently no definitive conclusions regarding the characteristics of multiple chemical sensitivity (MCS) and electromagnetic hypersensitivity (EHS). This study aimed to determine the prevalence and correlation of MCS and EHS with age, sex, and depression in the Japanese population. Methods An anonymous self-report questionnaire was distributed to 2,007 participants. Variables such as MCS, EHS, depression score, and demographic characteristics were individually evaluated using the U-test, chi-squared test, and correlation analyses. Moreover, we performed a covariance structure analysis to build a structural equation model. Results Older individuals and women were more likely to exhibit MCS and EHS symptoms. Moreover, depression was correlated with MCS and EHS. Conclusions Although MCS and EHS are strongly correlated, they exhibit distinct characteristics and symptoms, indicating that they can be regarded as separate conditions.
  • Atsushi Mizukoshi; Sachiko Hojo; Kenichi Azuma; Masami Mizuki; Mikio Miyata; Hideo Ogura; Kou Sakabe; Naomi Tsurikisawa; Chiyako Oshikata; Jiro Okumura
    Environmental Sciences Europe 35 32  2023/04 [Refereed]
  • Shinako Inaida; Atsushi Mizukoshi; Kenich Azuma; Jiro Okumura
    Environmental Health and Preventive Medicine Japanese Society for Hygiene 28 18 - 18 1342-078X 2023/03 [Refereed]
  • Generation of Formaldehyde in Ambient Air from Volatile Organic Compounds Emitted from Waste Plastic Recycling Facilities
    Atsushi Mizukoshi
    JOURNAL OF JAPANESE SCIENTISTS 58 (1) 42 - 46 2023/02 [Invited]
  • シックハウス症候群とは何か
    水越 厚史
    保健の科学 64 (10月) 670 - 675 2022/10 [Invited]
  • Atsushi Mizukoshi; Jiro Okumura; Kenichi Azuma
    Indoor Air 2022 Proceedings 2022/09 [Refereed]
  • The fight or flight response system and the mechanism of stress intolerance.
    黒岩義之; 平井利明; 横田俊平; 水越厚史; 北條祥子
    脳神経内科(神経内科) 96 (5) 637 - 647 2022/05
  • Yoshiyuki Kuroiwa; Toshiaki Hirai; Atsushi Mizukoshi; Naomi Nakasato; Takahiro Suzuki; Shumpei Yokota; Sachiko Hojo
    The Autonomic Nervous System Japan Society of Neurovegetative Research 59 (1) 72 - 81 0288-9250 2022/04 [Refereed][Invited]
     
    There are various types of environmental stress to which humans are exposed: physical sensory stress (light, sound), chemical sensory stress (smell, chemicals), immune-coagulative stress, psychosocial stress, and internal environmental stress. Environmental stress hypersensitivity or intolerance is defined as a condition in which the body exhibits hypersensitivity of the stress sensory input system or insufficiency of the stress response output system to various environmental stresses, and as manifestation of hypothalamic stress intolerant and exhaustive syndrome or periventricular organ dysregulation syndrome, with multilayered autonomic, endocrine, and immunological symptoms, as well as a variety of systemic symptoms such as pain, fatigue, and memory impairment. Two types of environmental stress hypersensitivity or intolerance exist: idiopathic type with no apparent underlying diseases, and symptomatic type with apparent underlying diseases, such as myalgic encephalomyelitis and chronic fatigue syndrome, cerebrospinal fluid leak, HPV vaccination sequelae, COVID-19 chronic sequelae, sick house syndrome, and exposure to neonicotinoid insecticides. The pathogenesis and prevention of the disease were discussed, based on the 3-stage hypothesis. In the first genetic stage, genetic factors should control the ease or difficulty of developing environmental stress sensitivity or intolerance. In the second onset stage, the patient is exposed to environmental factors, and develops a constitutional tendency to be sensitive or intolerant to environmental stress, becoming a susceptible person. In the third trigger stage, environmental stress at a daily level, which is not bothering normal people at all, becomes a trigger factor for excessive stress sensitivity or intolerance, and the person becomes a sensitive or intolerant person.
  • Sachiko Hojo; Atsushi Mizukoshi; Yoshiyuki Kuroiwa
    The Autonomic Nervous System 59 (1) 37 - 50 2022/04 [Refereed][Invited]
  • Atsushi Mizukoshi; Sachiko Hojo; Yoshiyuki Kuroiwa; Kenichi Azuma; Chikako Nakama; Jiro Okumura
    The Autonomic Nervous System Japan Society of Neurovegetative Research 59 (1) 28 - 36 0288-9250 2022/04 [Refereed][Invited]
  • Yoshiyuki Kuroiwa; Toshiaki Hirai; Atsushi Mizukoshi; Naomi Nakasato; Takahiro Suzuki; Shunpei Yokota; Sachiko Hojo
    The Allergy in Practice 41 (14) 0285-6379 2021/12
  • Atsushi Mizukoshi; Chikako Nakama; Jiro Okumura; Kenichi Azuma
    Environment International Elsevier BV 147 106338 - 106338 0160-4120 2021/02 [Refereed]
     
    We assessed the risk of COVID-19 infection in a healthcare worker (HCW) from multiple pathways of exposure to SARS-CoV-2 in a health-care setting of short distance of 0.6 m between the HCW and a patient while caring, and evaluated the effectiveness of a face mask and a face shield using a model that combined previous infection-risk models. The multiple pathways of exposure included hand contact via contaminated surfaces and an HCW's fingers with droplets, droplet spray, and inhalation of inspirable and respirable particles. We assumed a scenario of medium contact time (MCT) and long contact time (LCT) over 1 day of care by an HCW. SARS-CoV-2 in the particles emitted by coughing, breathing, and vocalization (only in the LCT scenario) by the patient were considered. The contribution of the risk of infection of an HCW by SARS-CoV-2 from each pathway to the sum of the risks from all pathways depended on virus concentration in the saliva of the patient. At a virus concentration in the saliva of 101-105 PFU mL-1 concentration in the MCT scenario and 101-104 PFU mL-1 concentration in the LCT scenario, droplet spraying was the major pathway (60%-86%) of infection, followed by hand contact via contaminated surfaces (9%-32%). At a high virus concentration in the saliva (106-108 PFU mL-1 in the MCT scenario and 105-108 PFU mL-1 in the LCT scenario), hand contact via contaminated surfaces was the main contributor (41%-83%) to infection. The contribution of inhalation of inspirable particles was 4%-10% in all assumed cases. The contribution of inhalation of respirable particles increased as the virus concentration in the saliva increased, and reached 5%-27% at the high saliva concentration (107 and 108 PFU mL-1) in the assumed scenarios using higher dose-response function parameter (0.246) and comparable to other pathways, although these were worst and rare cases. Regarding the effectiveness of nonpharmaceutical interventions, the relative risk (RR) of an overall risk for an HCW with an intervention vs. an HCW without intervention was 0.36-0.37, 0.02-0.03, and <4.0 × 10-4 for a face mask, a face shield, and a face mask plus shield, respectively, in the likely median virus concentration in the saliva (102-104 PFU mL-1), suggesting that personal protective equipment decreased the infection risk by 63%->99.9%. In addition, the RR for a face mask worn by the patient, and a face mask worn by the patient plus increase of air change rate from 2 h-1 to 6 h-1 was <1.0 × 10-4 and <5.0 × 10-5, respectively in the same virus concentration in the saliva. Therefore, by modeling multiple pathways of exposure, the contribution of the infection risk from each pathway and the effectiveness of nonpharmaceutical interventions for COVID-19 were indicated quantitatively, and the importance of the use of a face mask and shield was confirmed.
  • 室内空気汚染の健康影響と予防対策
    水越 厚史
    クリーンテクノロジー 31 (1) 52 - 56 2021/01 [Invited]
  • Atsushi Mizukoshi; Naohide Shinohara; Kenichi Azuma; Chikako Nakama; Jiro Okumura
    16th Conference of the International Society of Indoor Air Quality and Climate: Creative and Smart Solutions for Better Built Environments, Indoor Air 2020 ABS-0838 6 pages  2020/11 [Refereed]
     
    Polyvinyl chloride (PVC) sheet containing a plasticizer may emit chemicals, including 2-ethyl-1-hexanol (2EH). There are various ozone sources in indoor and outdoor air. Thus, a time course change of these reaction products of PVC sheet and ozone was monitored using a volatile organic compound (VOC) component monitor in a 20-L chamber with ventilation (air exchange rate was 1.5 air changes per hour). After ozone exposure to the PVC sheet, the peak area of 2EH decreased and the peaks where the area increased were observed in a chromatograph for 3 h, suggesting the generation of oxidation products. The reaction rate constant of 2EH and ozone was 6.5 × 10-7 /ppb/s, and the ozone degradation velocity was 0.033 cm/s. Results suggested a gas-phase reaction of 2EH and ozone, accounting for total ozone decomposition of 2%. Because 2EH and secondary reaction products which were mainly straight-chain aldehyde coexisted with PVC sheet and ozone, PVC sheet may be a source of secondary reaction products, in addition to 2EH, after a certain reaction time.
  • Atsushi Iizuka; Atsushi Mizukoshi; Miyuki Noguchi; Akihiro Yamasaki
    PLOS ONE Public Library of Science (PLoS) 15 (10) e0239458 - e0239458 2020/10 [Refereed]
  • Mizukoshi, Atsushi; Azuma, Kenichi; Sugiyama, Shigehiro; Tanaka, Daisuke; Inoue, Masashi; Tokumura, Masahiro; Okumura, Jiro
    BUILDING AND ENVIRONMENT PERGAMON-ELSEVIER SCIENCE LTD 163 106320  0360-1323 2019/10 [Refereed]
     
    High ozone concentrations often exist under the reduced pressure conditions observed in aircraft cabins during flight. In this study, we measured the concentrations of the products obtained from the reaction of ozone with limonene in a simulated aircraft cabin environment (i.e., vacuum chamber at approximately 70 kPa). The concentration of total volatile organic compounds increased under reduced pressure when compared to that under atmospheric pressure, whereas the ozone concentration decreased during the hour after limonene was injected into the chamber. These changes can be partially explained by the increased evaporation of limonene under reduced pressure. With respect to secondary products, a decrease in particulate matter was observed under reduced pressure for an initial ozone concentration of 0.4-0.5 mg/m(3). In contrast, the effects of reduced pressure on the concentrations of gaseous products, such as formaldehyde and limonene oxide, were small when the initial ozone concentration was approximately 0.3 mg/m(3). These results indicate that the reaction between limonene and ozone under reduced pressure is similar to that occurring under atmospheric pressure.
  • Naohide Shinohara; Atsushi Mizukoshi; Mayumi Uchiyama; Hirofumi Tanaka
    PloS one 14 (9) e0222557  2019/09 [Refereed]
     
    Emission rates of diethylhexyl phthalate (DEHP) from building materials, such as vinyl floorings and wall paper, determined using a passive flux sampler (PFS) were constant over the week-long measurement period. Emission rates for vinyl floorings and wallpaper were linearly correlated to the inverse of diffusion distance, which corresponds to the internal depth of the PFS. Surface-air DEHP concentrations (y0) were estimated as 1.3-2.3 μg/m3 for materials having a boundary layer molecular diffusion rate-limiting step. The partition coefficient (Kmaterial-air) was estimated as 3.3-7.5 × 1010 for these materials. Additionally, emission rates of DEHP from same building materials determined using a micro-chamber were 4.5-6.1 μg/m2/h. Mass transfer coefficients in the micro-chamber (hm) were estimated by comparing the results using the PFS and micro-chamber, and these were 1.1-1.2 × 10-3 and 8.1 × 10-4 m/s for vinyl floorings (smooth surface) and wallpaper (rough surface), respectively. The thickness of boundary layer on the surface of building materials in the micro-chamber were estimated to be 2.5-2.6 and 3.7 mm for vinyl floorings and wallpaper, respectively.
  • Health effects and control of indoor air pollution
    Atsushi Mizukoshi; Satoshi Nakai; Miyuki Noguchi; Kazuhiro Hashimoto
    JAPAN SOCIETY FOR ATMOSPHERIC ENVIRONMENT 54 (5) A103  2019/09 [Invited]
  • Naohide Shinohara; Yukiyo Okazaki; Atsushi Mizukoshi; Shinji Wakamatsu
    Chemosphere Elsevier {BV} 222 923 - 931 2019/05 [Refereed]
  • Sachiko Hojo; Atsushi Mizukoshi
    Japanese Journal of Clinical Ecology 27 (2) 83 - 98 2019/04 [Refereed][Invited]
  • Sachiko Hojo; Atsushi Mizukoshi; Kenichi Azuma; Jiro Okumura; Masami Mizuki; Mikio Miyata
    PLoS ONE 14 (4) e0215144  2019/04 [Refereed]
     
    BACKGROUND & OBJECTIVES: The Quick Environmental Exposure and Sensitivity Inventory (QEESI) developed by Miller and Prihoda in the USA is used as a questionnaire for patients with multiple chemical sensitivity (MCS) in >10 countries. We developed a Japanese version of QEESI, assessed its reliability and validity, and defined original cut-off values for screening Japanese patients with MCS in 2003. Our recent study revealed that opportunities for exposure to various chemicals had increased for people in Japan, while subjective symptoms of MCS in patients had increased in severity. In this study, we considered new cut-off values that combined QEESI subscale scores based on the current situation in Japan. METHODS: The questionnaire used was a Japanese version of QEESI. The survey was conducted from 2012 to 2015. Participants were 111 patients with MCS (mean age: 46 ± 20, 81% female) initially diagnosed by physicians, and 444 age- and gender-matched controls not diagnosed with MCS by doctors. The discriminatory validity of QEESI scores of patients and controls were evaluated by logistic regression and receiver operating characteristic analyses when considering interactions of the Masking Index (ongoing chemical exposure). New combined cut-off values were then set. RESULTS: New combined cut-off values (meeting conditions of Chemical Intolerances ≥ 30, Symptom Severity ≥ 13, and Life Impacts ≥ 17) showed high sensitivity (82.0%) and specificity (94.4%). Using new criteria when considering ongoing chemical exposure, study participants were categorized as: Very suggestive, Somewhat suggestive, Problematic, and Not suggestive. Participants classified as Very suggestive included 25 (5.6%) controls. CONCLUSIONS: We have set new criteria with combined cut-off values based on current Japanese conditions. Such new criteria can be used for screening and as a diagnostic aid for Japanese patients with MCS and suggest approximately 6% of the Japanese general population may be classified as "Very suggestive people with MCS".
  • Hojo S; Mizukoshi A; Azuma K; Okumura J; Ishikawa S; Miyata M; Mizuki M; Ogura H; Sakabe K
    International journal of hygiene and environmental health 221 (8) 1085 - 1096 1438-4639 2018/09 [Refereed]
     
    © 2018 Elsevier GmbH Background: Recently, with rapid changes in the Japanese lifestyle, the clinical condition of patients with multiple chemical sensitivity (MCS) may also have undergone change. Thus, we conducted a new survey for subjective symptoms, ongoing chemical exposures, the prevalence of allergic diseases, and presumed onset/trigger factors in patients with MCS and compared results with those of an old survey from ten years ago. Methods: The new survey was conducted from 2012 to 2015 and the old survey was independently conducted from 1999 to 2003, meaning it was not a follow-up study. Patients were initially diagnosed by physicians at five medical institutions with MCS specialty outpatient services, with 111 and 103 patients participating in the new and old surveys, respectively. The controls were a general population living in Japan, with 1313 and 2382 participants in the new and old surveys, respectively. Subjective symptoms and ongoing chemical exposure were evaluated using a quick environmental exposure sensitivity inventory. Additionally, from clinical findings recorded by an attending physician, the prevalence of allergic diseases and presumed onset/trigger factors were evaluated. Differences between new and old surveys were analyzed using logistic regression analyses and significance tests. Results: Compared with ten years ago: (1) Regarding factors affecting patients with ongoing chemical exposures, the proportion of patients affected decreased significantly for two items only (insecticides and second-hand smoke). The proportion of controls showing ongoing exposure to 8 out of 10 items changed significantly. (2) In patients, scores for chemical intolerances, other intolerances, and life impacts increased significantly. (3) In terms of the prevalence of allergic diseases among patients with MCS, bronchial asthma (adjusted odds ratio [AOR]: 5.19), atopic dermatitis (AOR: 3.77), allergic rhinitis (AOR: 5.34), and food allergies (AOR: 2.63) increased significantly, while hay fever (AOR: 0.38) and drug allergies (AOR: 0.40) decreased significantly. (4) With regard to construction and renovation, which was the presumed predominant onset/trigger factor for MCS 10 years ago, this decreased from 68.9% to 35.1%; in contrast, electromagnetic fields (0.0%–26.1%), perfume (0.0%–20.7%), and medical treatment (1.9%–7.2%) increased significantly, confirming the diversification of onset/trigger factors. Conclusion: Compared to ten years ago, for patients with MCS, an increase in avoidance behavior toward chemical substance exposures, which were presumed to be aggravating factors for symptoms, was confirmed. It has been suggested that the ongoing chemical exposure of the general population in Japan has largely changed. In addition, for patients with MCS, chemical intolerances and life impacts have become severe, the prevalence of the main allergic diseases has increased, and onset/trigger factors have become diversified.
  • 奥村 二郎; 東 賢一; 水越 厚史
    公衆衛生 株式会社医学書院 82 (8) 626 - 630 0368-5187 2018/08 [Invited]
  • Mizukoshi A; Azuma K; Sugiyama S; Tanaka D; Inoue M; Tokumura M; Okumura J
    Proceedings of the 15th International Conference on Indoor Air Quality and Climate ID498 8 pages  2018/07 [Refereed]
     
    In an aircraft cabin during flight, high ozone concentrations often exist in reduced pressure conditions. We measured the concentration of products from the reaction of ozone with limonene in a vacuum chamber, which was used to simulate an aircraft cabin, at approximately 70 kPa. Results indicated that under reduced pressure, the concentration of total volatile organic compounds increased and ozone concentration decreased in comparison with these concentrations at atmospheric pressure. Evidence suggested that these differences were observed because of the increased evaporation of volatile organic compounds under reduced pressure. Regarding secondary products, a decrease in particulate matter was observed under reduced pressure at approximately 0.5 mg/m3 ozone concentration. In contrast, the influence of total pressure on the concentration of gaseous products like formaldehyde, 6-methyl-5-hepten-2-one, and limonene oxide was small at approximately 0.3 mg/m3 ozone concentration. The reaction between limonene and ozone under reduced pressure is thus suggested to be similar to that under atmospheric pressure.
  • Atsushi Mizukoshi; Yosuke Kurosaki; Naomichi Yamamoto; Miyuki Noguchi; Atsushi Iizuka; Akihiro Yamasaki; Yukio Yanagisawa
    Wood Science and Technology Springer Verlag 52 (2) 567 - 579 0043-7719 2018/03 [Refereed]
     
    High concentrations of acetaldehyde are often observed in indoor environments. One possible source of this is acetaldehyde formation produced by ethanol from wood building materials. To characterize indoor acetaldehyde formation and propose methods for its reduction, chamber-based experiments were conducted in which alcohols were added to pulverized solid woods. The results indicated that acetaldehyde was generated from the ethanol-added wood materials, and softwoods, namely Japanese cedar, Japanese cypress, and Swedish redwood generated more acetaldehyde than the other three woods. The experiments using different types of alcohols of methanol, ethanol, 1-propanol, and 2-propanol revealed a tendency similar to the reported enzymatic profile of the higher plant-derived alcohol dehydrogenase. It was confirmed that acetaldehyde generation was reduced by treatment methods typically used for inactivating enzymes, namely chemical treatments using pyrazole, borate, and urea and thermal treatments. The findings suggest that the chemical and thermal treatment methods are useful to reduce acetaldehyde generation in indoor environments.
  • Development of ETS and odor removal system. Field study of smoking room in an office building
    佐伯寅彦; 岩間裕樹; 穴井俊博; 湯懐鵬; 山北桜子; 坂本裕; 津島健; 野口美由貴; 水越厚史; 柳沢幸雄
    新菱冷熱中央研究所報 24 9 - 13 2017/08 [Refereed]
  • Mizukoshi, A.
    Chemical Sensitivity and Sick-Building Syndrome Chemical Sensitivity and Sick-Building Syndrome 2017
  • 奥村二郎; 東 賢一; 水越厚史
    日本職業・環境アレルギー学会雑誌 日本職業・環境アレルギー学会 24 (2) 11 - 16 1349-5461 2017 [Invited]
  • Kou Sakabe; Minoru Kimura; Hayato Terayama; Masashi Tsunoda; Eriko Miyajima; Hirohisa Takano; Kenichi Azuma; Atsushi Mizukoshi; Tetsuya Matsuda; Chisato Mori; Mikio Miyata; Satoshi Ishikawa; Yoshiharu Aizawa
    Japanese Journal of Clinical Ecology 25 (2) 49 - 54 2016/12 [Refereed][Invited]
  • Miyuki Noguchi; Atsushi Mizukoshi; Yukio Yanagisawa; Akihiro Yamasaki
    International Journal of Environmental Research and Public Health MDPI AG 13 (7) 736 - 736 1660-4601 2016/07
  • Investigation of reaction products of ozone and organic compounds in a simulated aircraft cabin
    Atsushi Mizukoshi; Kenichi Azuma; Daisuke Tanaka; Masashi Inoue; Shinsuke Usui; Jiro Okumura
    Proceedings of the 14th International Conference on Indoor Air Quality and Climate ID358 7 pages  2016/07 [Refereed]
  • 水越厚史; 東賢一
    住まいとでんき 28 (3) 1 - 4 2187-8412 2016/03 [Invited]
  • Masahiro Tokumura; Atsushi Mizukoshi; Miyuki Noguchi; Yuko Wada; Yuri Usami; Takako Yamaki; Yukio Yanagisawa
    AIMS Environmental Science 3 (1) 159 - 167 2016/03 [Refereed]
  • Atsushi Mizukoshi; Kazukiyo Kumagai; Naomichi Yamamoto; Miyuki Noguchi; Kazuhiro Yoshiuchi; Hiroaki Kumano; Kou Sakabe; Yukio Yanagisawa
    INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH MDPI AG 12 (10) 12446 - 12465 1660-4601 2015/10 [Refereed]
     
    In-situ real-time monitoring of volatile organic compound (VOC) exposure and heart rate variability (HRV) were conducted for eight multiple chemical sensitivity (MCS) patients using a VOC monitor, a Holter monitor, and a time-activity questionnaire for 24 h to identify the relationship between VOC exposure, biological effects, and subjective symptoms in actual life. The results revealed no significantly different parameters for averaged values such as VOC concentration, HF (high frequency), and LF (low frequency) to HF ratio compared with previous data from healthy subjects (Int. J. Environ. Res. Public Health2010, 7, 4127-4138). Significant negative correlations for four subjects were observed between HF and amounts of VOC change. These results suggest that some patients show inhibition of parasympathetic activities along with VOC exposure as observed in healthy subjects. Comparing the parameters during subjective symptoms and normal condition, VOC concentration and/or VOC change were high except for one subject. HF values were low for five subjects during subjective symptoms. Examining the time-series data for VOC exposure and HF of each subject showed that the subjective symptoms, VOC exposure, and HF seemed well related in some symptoms. Based on these characteristics, prevention measures of symptoms for each subject may be proposed.
  • Rumi Konuma; Kiwamu Umezawa; Atsushi Mizukoshi; Kensuke Kawarada; Makoto Yoshida
    BIOTECHNOLOGY LETTERS SPRINGER 37 (9) 1845 - 1852 0141-5492 2015/09 [Refereed]
     
    Microbial volatile organic compounds (MVOCs) produced by the brown-rot fungus Fomitopsis palustris and white-rot fungus Trametes versicolor grown on wood chip and potato dextrose agar were analyzed by GC-MS. In total, 110 organic compounds were identified as MVOCs. Among them, only 23 were MVOCs commonly observed in both types of fungi, indicating that the fungi have differential MVOC expression profiles. In addition, F. palustris and T. versicolor produced 38 and 22 MVOCs, respectively, which were detected only after cultivation on wood chip. This suggests that the fungi specifically released these MVOCs when degrading the cell-wall structure of the wood. Time course analysis of MVOC emission showed that both types of fungi produced the majority of MVOCs during the active phase of wood degradation. As both fungi produced specific MVOCs in the course of wood degradation indicates the possibility of the application of MVOCs as detection markers for wood-decay fungus existing in woody materials.
  • MIZUKOSHI ATSUSHI; NOGUCHI MIYUKI; YAMAMOTO SOICHIRO; KAWAKAMI RISA; OTSUKA TOSHIHIRO; YAMAGUCHI MAKOTO; YANAGISAWA YUKIO
    室内環境 Society of Indoor Environment, Japan 18 (1) 3-14 (J-STAGE) - 14 1882-0395 2015/06 [Refereed]
     
    In office buildings, indoor air quality is managed on the basis of an indoor CO2 concentration of 1000ppm or less under the Maintenance of Sanitation in Buildings Act. However, in recent years there have been growing concerns about sick building syndrome, caused by unregulated volatile organic compounds (VOCs) that are not included in the list of indoor concentration guideline compounds defined by the Ministry of Health, Labour and Welfare of Japan. Therefore, the importance of managing indoor total VOC (TVOC) concentration is being recognized. Energy conservation in office buildings is also an important issue, and reducing air conditioning loads by controlling the amount of introduced outdoor air is one promising approach. The objective of this study is to verify the energy conservation potential of air-conditioning control, using indoor CO2 and TVOC concentrations as indicators. We conducted a simulation experiment in an office space in which people were not present and made long-term measurements in actual work environments. The simulation results showed that CO2 concentration increased as the amount of introduced outdoor air decreased, when supply air was introduced normally. However, following the reduction of the supply air, CO2 concentration distribution was generated. Additionally, long-term measurements made in actual work environments showed differing trends in CO2 and TVOC fluctuations. This result indicates the necessity of using two indicators to manage indoor air quality. We estimated the amount of outdoor air introduced by controlling air conditioning based on regulation values 400 μg/m3 for TVOC and 1000ppm for CO2, and this amount could have been reduced by 43% of set value of the amount of introduced outdoor air. Consequently, in buildings with low VOC emissions, it is possible that the amount of introduced outdoor air can be reduced by monitoring CO2 and TVOC concentrations, thereby contributing to energy conservation.
  • Mizukoshi A; Azuma K; Okumura J
    Proceedings of the Healthy Buildings Europe 2015 ID616 1 - 2 2015/05 [Refereed]
  • KONUMA RUMI; MIZUKOSHI ATSUSHI; KAWARADA KENSUKE; YOSHIDA MAKOTO
    木材保存 JAPAN WOOD PRESERVING ASSOCIATION 41 (3) 108 - 118 0287-9255 2015/05 [Refereed]
     
    Microbial volatile organic compounds (MVOCs) could be used to nondestructively detect hidden wood decay fungi in dwellings, because these compounds can diffuse from inside the walls to the indoor environment through the wallpaper. To develop the diagnostic method of MVOCs emitted from wood decay fungi, MVOCs from Fomitopsis palustris, which is the industrial standard of brown rot fungi in Japan, grown on PDA were analyzed by using GC/MS with a thermal desorption system, proton transfer reaction (PTR)-MS, and head space-solid phase micro extraction (HS-SPME)-GC/MS. Total 26 of MVOCs were detected when MVOCs were analyzed by GC/MS with a thermal desorption system. Among them, the amounts of major MVOCs (methyl isobutyrate, 2, 5-dimethylfuran, 1-octene, methyl tiglate, methyl 2-furoate, 3-octanone, and methyl benzoate) were monitored by PTR-MS during 9 days of cultivation time, and a differential emission patterns were observed deperding on the MVOCs. To achieve a small scale determination, MVOCs from F. palustris grown on PDA were analyzed by HS-SPME-GC/MS, and 7 of MVOCs were detected in a short time compared with GC/MS with a thermal desorption system. The information obtained in the present study would be useful to develop the analytical method of MVOCs emitted from wood decay fungi grown in wood materials.
  • Shintaro Shirato; Atsushi Iizuka; Atsushi Mizukoshi; Miyuki Noguchi; Akihiro Yamasaki; Yukio Yanagisawa
    INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH MDPI AG 12 (3) 2950 - 2966 1660-4601 2015/03 [Refereed]
     
    Continuous ambient air monitoring systems have been introduced worldwide. However, such monitoring forces autonomous communities to bear a significant financial burden. Thus, it is important to identify pollutant-monitoring stations that are less efficient, while minimizing loss of data quality and mitigating effects on the determination of spatiotemporal trends of pollutants. This study describes a procedure for optimizing a constant ambient air monitoring system in the Kanto region of Japan. Constant ambient air monitoring stations in the area were topologically classified into four groups by cluster analysis and principle component analysis. Then, air pollution characteristics in each area were reviewed using concentration contour maps and average pollution concentrations. We then introduced three simple criteria to reduce the number of monitoring stations: (1) retain the monitoring station if there were similarities between its data and average data of the group to which it belongs; (2) retain the station if its data showed higher concentrations; and (3) retain the station if the monitored concentration levels had an increasing trend. With this procedure, the total number of air monitoring stations in suburban and urban areas was reduced by 36.5%. The introduction of three new types of monitoring stations is proposed, namely, mobile, for local non-methane hydrocarbon pollution, and O-x-prioritized.
  • MAEDA YASUHIRO; SAEKI TORAHIKO; FUKADA KEN; TANG HUAIPENG; NOGUCHI MIYUKI; MIZUKOSHI ATSUSHI; YANAGISAWA YUKIO
    新菱冷熱中央研究所報 21 85 - 95 2014/08
  • Atsushi Iizuka; Shintaro Shirato; Atsushi Mizukoshi; Miyuki Noguchi; Akihiro Yamasaki; Yukio Yanagisawa
    INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH MDPI AG 11 (7) 6844 - 6855 1660-4601 2014/07 [Refereed]
     
    This study demonstrates an application of cluster analysis to constant ambient air monitoring data of four pollutants in the Kanto region: NOx, photochemical oxidant (O-x), suspended particulate matter, and non-methane hydrocarbons. Constant ambient air monitoring can provide important information about the surrounding atmospheric pollution. However, at the same time, ambient air monitoring can place a significant financial burden on some autonomous communities. Thus, it has been necessary to reduce both the number of monitoring stations and the number of chemicals monitored. To achieve this, it is necessary to identify those monitoring stations and pollutants that are least significant, while minimizing the loss of data quality and mitigating the effects on the determination of any spatial and temporal trends of the pollutants. Through employing cluster analysis, it was established that the ambient monitoring stations in the Kanto region could be clustered topologically for NOx and O-x into eight groups. From the results of this analysis, it was possible to identify the similarities in site characteristics and pollutant behaviors.
  • 奥村二郎; 東賢一; 萬羽郁子; 水越厚史
    アレルギー・免疫 (株)医薬ジャーナル社 21 (5) 816 - 822 1344-6932 2014/04 [Refereed][Invited]
     
    ガイドラインでは、職業性アレルギー疾患は「誰の責任か?」というQuestionに始まり、労働衛生法令における、業務上疾病に対する事業者(使用者)の責任、職場での健康診断、療養・休業補償などの労災保険を取り上げた。本稿では、法律やその施行にあたる行政的な観点を加えて概説した。併せて、今後発見されるアレルギー要因による新規の疾患の認定にあたって、診断精度の向上と症例情報の収集に有用な職業性アレルギー疾患に対する「疾病登録」の構築についても考察を加えた。(著者抄録)
  • 染川正一; 井上潤; 水越厚史; 萩原利哉; 藤井恭子; 小島正行; 篠田勉
    東京都立産業技術研究センター研究報告 東京都立産業技術研究センター 8 (8) 34 - 37 1881-8676 2013/09 [Refereed]
  • 前田康博; 佐伯寅彦; TANG Huaipeng; 野口美由貴; 水越厚史; 柳沢幸雄
    新菱冷熱中央研究所報 20 55 - 62 2013/08
  • N. Shinohara; M. Tokumura; M. Kazama; H. Yoshino; S. Ochiai; A. Mizukoshi
    Indoor Air 23 (4) 332 - 341 0905-6947 2013/08 [Refereed]
     
    This study measured air exchange rates, indoor concentrations of aldehydes and volatile organic compounds (VOCs), and radioactivity levels at 19 temporary houses in different temporary housing estate constructed in Minamisoma City following the Great East Japan Earthquake. The 19 surveyed houses represented all of the companies assigned to construct temporary houses in that Minamisoma City. Data were collected shortly after construction and before occupation, from August 2011 to January 2012. Mean air exchange rates in the temporary houses were 0.28/h, with no variation according to housing types and construction date. Mean indoor concentrations of formaldehyde, acetaldehyde, toluene, ethylbenzene, m/p-xylene, o-xylene, styrene, p-dichlorobenzene, tetradecane, and total VOCs (TVOCs) were 29.2, 72.7, 14.6, 6.35, 3.05, 1.81, 7.29, 14.3, 8.32, and 901 μg/m3, respectively. The levels of acetaldehyde and TVOCs exceeded the indoor guideline (48 μg/m3) and interim target (400 μg/m3) in more than half of the 31 rooms tested. In addition to guideline chemicals, terpenes (α-pinene and d-limonene) and acetic esters (butyl acetate and ethyl acetate) were often detected in these houses. The indoor radiation levels measured by a Geiger-Müller tube (Mean: 0.22 μSv/h) were lower than those recorded outdoors (Mean: 0.42 μSv/h), although the shielding effect of the houses was less than for other types of buildings. © 2013 John Wiley & Sons A/S.
  • Miyuki Noguchi; Atsushi Mizukoshi; Yasuhiro Maeda; Torahiko Saeki; Ken Fukada; Huaipeng Tang; Yukio Yanagisawa
    Indoor Environment Society of Indoor Environment, Japan 15 (2) 125 - 134 1882-0395 2012/12 [Refereed]
     
    Removal efficiencies of environmental tobacco smoke (ETS) and its odor with newly developed ETS removal equipment were evaluated. The developed equipment consists of two units: Particulate and VOC Removal Unit (PVRU) and Odor Removal Unit (ORU) connected in series. The 1st unit is PVRU for removing suspended particulate matter (SPM) and volatile organic compounds (VOC) composed of two air filters (HEPA: High Efficiency Particulate Air filter and activate charcoal filter). The 2nd unit is ORU for removing acetaldehyde and ETS odor composed of a wet element using chemical absorbent containing amino acids mixture. First, removal experiment of acetaldehyde in air was carried out. In the experiment, we measured acetaldehyde concentration at inlet of PVRU, and outlet of ORU. Removal efficiency of acetaldehyde by the developed equipment was higher than 90%. Next, removal experiment of ETS and its odor was carried out during tobacco smoke generating. We found that SPM and most of VOC except oxygenated compounds were almost completely removed by PVRU. The removal efficiencies of acetaldehyde and odor by PVRU were 80%, 90% respectively, and the removal efficiency of acetaldehyde was decreased with time. But the removal efficiencies of these components after ORU were 95%, 99% respectively. Acetaldehyde is considered to be chemically absorbed by amino acids in the chemical absorbent, and its absorption capacity of acetaldehyde was at least 70 mg L-1. The removal efficiency was confirmed to be maintained after treatment of tobacco smoke of 400 cigarettes.
  • Miyuki Noguchi; Atsushi Mizukoshi; Yasuhiro Maeda; Torahiko Saeki; Ken Fukada; Huaipeng Tang; Yukio Yanagisawa
    Indoor Environment Society of Indoor Environment, Japan 15 (2) 135 - 145 1882-0395 2012/12 [Refereed]
     
    We evaluated air quality of a quasi-office (194.4 m3) in which a smoking booth (24.3 m3) was installed with developed ETS removal equipment (Developed Equipment). The ventilation rate of the office was set 1440 m3 h-1 and the tobacco smoke continuously emitted from 8 cigarettes was processed by the developed equipment with circulation air flow at 1200 m3 h-1 to be exhausted into the office. Increase in the concentrations of tobacco smoke ingredients in the office room was prevented by operating the developed equipment even when 8 cigarettes were burned. Concentrations of carbon monoxide (CO), which was included in tobacco smoke but not be removed by the developed equipment, were increased. However, the concentrations were in range of 0 to 2.7 ppm, which are below the indoor standard value at 10 ppm. This is due to the high ventilation rate. The moisture content, which was emitted by the developed equipment were decreased by the ventilation system. Observed distribution of concentrations of the ingredients of ETS in the office room was not affected by the position of the ventilation exhaust, back of the office room or above developed equipment's outlet. Thus, if we can set the ventilation rate high enough for the volume of the office room, the office air quality can be kept clean. Observed concentrations were well agreed with the CFD simulation results. We can estimate the performance of the smoking booth before actual installation.
  • Masahiro Tokumura; Yuko Wada; Yuri Usami; Takako Yamaki; Atsushi Mizukoshi; Miyuki Noguchi; Yukio Yanagisawa
    CHEMOSPHERE PERGAMON-ELSEVIER SCIENCE LTD 89 (10) 1238 - 1242 0045-6535 2012/11 [Refereed]
     
    The photo-Fenton reaction was applied as a novel method for the removal of volatile organic compounds (VOCs) in the gas phase, and its effectiveness was experimentally examined. In conventional VOCs removal methods using a photocatalyst or ozone, VOCs are oxidized in the gas phase. Therefore, incompletely oxidized intermediates, which may have adverse effects on health, are likely to contaminate the treated air. On the other hand, in the VOCs removal method developed in this study, because the VOCs are oxidized in the liquid phase by the photo-Fenton reaction, any incompletely oxidized intermediates produced are confined to the liquid phase. As a result, the contamination of the treated air by these harmful intermediates can be prevented. Using a semi-batch process, it was found that the removal efficiency for toluene in a one-pass test (residence time of 17 s) was 61%, for an inlet toluene gas concentration of 930 ppbv, an initial iron ion concentration of 20 mg L-1. and an initial hydrogen peroxide concentration of 630 mg L-1. The removal efficiency was almost constant as long as H2O2 was present in the solution. Proton transfer reaction mass spectrometry analysis confirmed the absence of any incompletely oxidized intermediates in the treated air. (C) 2012 Elsevier Ltd. All rights reserved.
  • Masahiro Tokumura; Yuko Wada; Yuri Usami; Takako Yamaki; Atsushi Mizukoshi; Miyuki Noguchi; Yukio Yanagisawa
    Indoor Environment Society of Indoor Environment, Japan 15 (1) 27 - 38 1882-0395 2012/06 [Refereed]
     
    Removal of gaseous volatile organic compounds (VOCs) in indoor air by the photo Fenton reaction using a gas-liquid two-phase photoreactor was investigated. In proposed air cleaning process, the removal of VOCs in the gas phase involves mass transfer with simultaneous chemical decomposition. As the first step of the process, the mass transfer of VOCs from the gas phase to the liquid phase occurs in the gas-liquid two-phase photoreactor. This is followed by the oxidative reaction due to highly-reactive hydroxyl radicals generated by the photo Fenton reaction. The decrease in dissolved VOCs concentration by the photo Fenton reaction leads to enhance the mass transfer. In this study, acetaldehyde as a model hydrophilic VOCs and toluene as a hydrophobic VOCs were used. It was found from the results of one-pass tests that 97% of gaseous acetaldehyde and 50% of gaseous toluene could be removed at the inlet acetaldehyde concentration of 1000ppbv and the inlet toluene concentration of 1000ppbv, respectively. In the proposed air cleaning process, because VOCs oxidations occur in the liquid phase, potential harmful incomplete oxidative degradation products could not be detected by PTR-MS.
  • Atsushi Iizuka; Hiroaki Ishizaki; Atsushi Mizukoshi; Miyuki Noguchi; Akihiro Yamasaki; Yukio Yanagisawa
    INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH AMER CHEMICAL SOC 50 (21) 11808 - 11814 0888-5885 2011/11 [Refereed]
     
    Experimental study was conducted on the simultaneous process of decomposition and fixation of fluoride of F-gases. HFC-134a, a hydrofluorocarbon (HFC), used most widely, was selected as a model gas, and its decomposition performances were examined in a tube type reactor with and without waste concrete powder. Decomposition of HFC-134a was observed at temperatures above 500 degrees C, while no thermal decomposition occurred below 750 degrees C without waste concrete. The results for the differential type reactor with high SV demonstrated that the calcium reaction ratio in the waste concrete reached about 50 mol % after 10 min of reaction. Thermal decomposition of HFC-134a was promoted by increasing the reaction temperature. The particle size of the waste concrete within the range studied scarcely affected the decomposition rate. An increase in HFC-134a concentration resulted in a higher calcium reaction ratio of waste concrete. For the integral reactor conditions with packed bed of waste concrete, almost all HFC-134a in the feed gas could be decomposed until 20 min of the reaction time.
  • Miyuki Noguchi; Atsushi Mizukoshi; Yukio Yanagisawa
    AIJ Journal of Technology and Design 日本建築学会 17 (36) 577 - 582 1341-9463 2011/06 [Refereed]
     
    Evaluation of air quality by concentration of just only target compounds has the possibility of a lot of trouble. In this study, we evaluated the air quality of new nursery room. As a result, the TVOC concentrations greatly exceeded the indoor target value (400 μg/m3). Moreover, we verified various ventilation methods such as continuous running of kitchen fan, securing of ventilation routes and introduction of additional ventilating fan, and the concentration drastically decreased to one-tenth compared with opening status after 3 months. In addition, ventilation rates estimated by TVOC concentration change of PID monitor increased.
  • Kentaro Oka; Atsushi Iizuka; Yasuo Inoue; Atsushi Mizukoshi; Miyuki Noguchi; Akihiro Yamasaki; Yukio Yanagisawa
    INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH MDPI AG 7 (12) 4100 - 4110 1660-4601 2010/12 [Refereed]
     
    A combined integration analysis and real time monitoring (Peak Capture System) system was developed for volatile organic compounds (VOCs). Individual integration analysis and real time monitoring can be used to qualitatively and quantitatively analyze VOCs in the atmosphere and in indoor environments and determine the variation in total VOC (TVOC) concentration with time, respectively. In the Peak Capture System, real time monitoring was used to predict future elevations in the TVOC concentration (peak), and this was used an indicator of when to collect (capture) ambient air samples for integration analysis. This enabled qualitative and quantitative analysis of VOCs when the TVOC concentration was high. We developed an algorithm to predict variation in the TVOC concentration, and constructed an automatic system to initiate air sampling for integration analysis. With the system, auto-sampling and analysis of VOCs in a conventional house were conducted. In comparison with background concentrations, the results of peak analysis enabled identification of compounds whose concentration rose. This also enabled an evaluation of possible VOC emission sources.
  • Atsushi Iizuka; Atsushi Mizukoshi; Kyoko Saito; Takako Yamaki; Miyuki Noguchi; Yuko Yanagisawa
    Indoor Environment Society of Indoor Environment, Japan 13 (2) 155 - 161 1882-0395 2010/12 [Refereed]
     
    The emission flux of styrene monomer from expanded polystyrene beads (EPSB), expanded polystyrene (EPS) and others, such as pillow, cushion and soft toy samples was measured by using passive flux sampler (PFS). The styrene emission flux was measured at 298 K (11-220 μg/m2/h), 309 K (32-620 μg/m2/h), and 323 K (203-2.23×103 μg/m2/h) and it was found that the emission flux increased with increase in temperature. Apparent activation energy for styrene emission flux from samples was measured < 100 kJ/mol. Activation energy for thermal degradation reaction of polystyrene chain was reported 210 kJ/mol. Thus, it is observed that the rate controlling step is not degradation reaction step but may be mass transfer steps. It may face some difficulties for the users of expanded polystyrene-used products as if expose styrene and other chemical compounds.
  • Atsushi Mizukoshi; Kazukiyo Kumagai; Naomichi Yamamoto; Miyuki Noguchi; Kazuhiro Yoshiuchi; Hiroaki Kumano; Yukio Yanagisawa
    INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH MDPI AG 7 (12) 4127 - 4138 1660-4601 2010/12 [Refereed]
     
    While various volatile organic compounds (VOCs) are known to show neurotoxic effects, the detailed mechanisms of the action of VOCs on the autonomic nervous system are not fully understood, partially because objective and quantitative measures to indicate neural abnormalities are still under development. Nevertheless, heart rate variability (HRV) has been recently proposed as an indicative measure of the autonomic effects. In this study, we used HRV as an indicative measure of the autonomic effrects to relate their values to the personal concentrations of VOCs measured by a real-time VOC monitor. The measurements were conducted for 24 hours on seven healthy subjects under usual daily life conditions. The results showed HF powers were significantly decreased for six subjects when the changes of total volatile organic compound (TVOC) concentrations were large, indicating a suppression of parasympathetic nervous activity induced by the exposure to VOCs. The present study indicated these real-time monitoring was useful to characterize the trends of VOC exposures and their effects on autonomic nervous system.
  • Yusuke Ishizuka; Masahiro Tokumura; Atsushi Mizukoshi; Miyuki Noguchi; Yukio Yanagisawa
    INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH MDPI AG 7 (11) 3853 - 3870 1660-4601 2010/11 [Refereed]
     
    Continuous measurements using proton transfer reaction mass spectrometry (PTR-MS) can be used to describe the production processes of secondary products during ozone induced oxidation of terpenes. Terpenes are emitted from woody building materials, and ozone is generated from ozone air purifiers and copy machines in indoor environments. Carbonyl compounds (CCs) are emitted by human activities such as smoking and drinking alcohol. Moreover, CCs are generated during ozone oxidation of terpenes. Therefore, coexistent CCs should affect the ozone oxidation. This study has focused on the measurement of secondary products during the ozone oxidation of terpenes based on the use of PTR-MS analysis and effects of coexistent CCs on oxidized products. Experiments were performed in a fluoroplastic bag containing alpha-pinene or limonene as terpenes, ozone and acetaldehyde or formaldehyde as coexistent CCs adjusted to predetermined concentrations. Continuous measurements by PTR-MS were conducted after mixing of terpenes, ozone and CCs, and time changes of volatile organic compounds (VOCs) concentrations were monitored. Results showed that, high-molecular weight intermediates disappeared gradually with elapsed time, though the production of high-molecular weight intermediates was observed at the beginning. This phenomenon suggested that the ozone oxidation of terpenes generated ultrafine particles. Coexistent CCs affected the ozone oxidation of alpha-pinene more than limonene.
  • Kyoko Yamashita; Miyuki Noguchi; Atsushi Mizukoshi; Yukio Yanagisawa
    INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH MDPI AG 7 (9) 3489 - 3498 1660-4601 2010/09 [Refereed]
     
    The irreversible removal of acetaldehyde from indoor air via a chemical reaction with amino acids was investigated. To compare effectiveness, five types of amino acid (glycine, L-lysine, L-methionine, L-cysteine, and L-cystine) were used as the reactants. First, acetaldehyde-laden air was introduced into aqueous solutions of each amino acid and the removal abilities were compared. Among the five amino acids, L-cysteine solution showed much higher removal efficiency, while the other amino acids solutions didn't show any significant differences from the removal efficiency of water used as a control. Next, as a test of the removal abilities of acetaldehyde by semi-solid L-cysteine, a gel containing L-cysteine solution was put in a fluororesin bag filled with acetaldehyde gas, and the change of acetaldehyde concentration was measured. The L-cysteine-containing gel removed 80% of the acetaldehyde in the air within 24 hours. The removal ability likely depended on the unique reaction whereby acetaldehyde and L-cysteine rapidly produce 2-methylthiazolidine-4-carboxylic acid. These results suggested that the reaction between acetaldehyde and L-cysteine has possibilities for irreversibly removing toxic acetaldehyde from indoor air.
  • Atsushi Mizukoshi; Toshio Kinoshita; Miyuki Noguchi; Kyoko Saito; Yukio Yanagisawa
    Bulletin of Tokyo Metropolitan Industrial Technology Research Institute 東京都立産業技術研究センター (5) 52 - 55 1881-8676 2010/09 [Refereed]
  • Atsushi Mizukoshi; Miyuki Noguchi; Yueyong Ni; Yukio Yanagisawa
    Bulletin of Tokyo Metropolitan Industrial Technology Research Institute 東京都立産業技術研究センター (4) 8 - 11 1881-8676 2009/09 [Refereed]
  • Naohide Shinohara; Yuya Kai; Atsushi Mizukoshi; Minoru Fujii; Kazukiyo Kumagai; Yumiko Okuizumi; Miki Jona; Yukio Yanagisawa
    BUILDING AND ENVIRONMENT PERGAMON-ELSEVIER SCIENCE LTD 44 (5) 859 - 863 0360-1323 2009/05 [Refereed]
     
    In indoor environments with high levels of air pollution, it is desirable to remove major sources of emissions to improve air quality. In order to identify the emission sources that contribute most to the concentrations of indoor air pollutants. we used passive flux samplers (PFSs) to measure emission rates of carbonyl compounds and volatile organic compounds (VOCs) from many of the building materials and furnishings present in a room in a reinforced concrete building in Tokyo, Japan. The emission flux of formaldehyde from a desk was high (125 mu g/m(2)/h). whereas fluxes from a door and flooring were low (21.5 and 16.5 mu g/m(2)/h. respectively). The emission fluxes of toluene from the ceiling and the carpet were high (80.0 and 72.3 mu g/m(2)/h, respectively), whereas that from the flooring was low (9.09 mu g/m(2)/h). The indoor and outdoor concentrations of formaldehyde were 61.5 and 8.64 mu g/m(3), respectively, and those of toluene were 43.2 and 17.5 mu g/m(3), respectively. The air exchange rate of the room as measured by the perfluorocarbon tracer (PFT) method was 1.84/h. Taking into consideration the area of the emission sources, the carpet, ceiling, and walls were identified as the principal emission sources, contributing 24%, 20%, and 22% of the formaldehyde, respectively, and 22%, 27%, and 14% of the toluene, respectively, assuming that the emission rate from every major emission sources could be measured. in contrast, the door, the flooring, and the desk contributed little to the indoor levels of formaldehyde (1.0%. 0.54%, and 4.1%, respectively) and toluene (2.2%, 0.31%, and 0.85%, respectively). (C) 2008 Elsevier Ltd. All rights reserved.
  • Kyoko Yamashita; Naomichi Yamamoto; Atsushi Mizukoshi; Miyuki Noguchi; Yueyong Ni; Yukio Yanagisawa
    JOURNAL OF THE AIR & WASTE MANAGEMENT ASSOCIATION AIR & WASTE MANAGEMENT ASSOC 59 (3) 273 - 278 1047-3289 2009/03 [Refereed]
     
    To characterize potential air pollution issues related to recycling facilities of waste plastics, volatile organic compounds (VOCs) emitted from melted virgin and waste plastics pellets were analyzed. In this study, laboratory experiments were performed to melt virgin and waste plastic pellets under various temperatures (150, 200, and 250 degrees C) and atmospheres (air and nitrogen [N(2) ]). In the study presented here, low-density polyethylene (LIVE), polypropylene (PP), polystyrene (PS) and the recycled waste plastic pellets were used. The VOCs generated from each plastic pellets were collected by Tenax/Carboxen adsorbent tubes and analyzed by thermal desorption-gas chromatography/mass spectrometry (TD-GC/MS).The result showed the higher temperatures generated larger amounts of total VOCs (TVOCs).The VOCs emitted from the virgin plastic pellets likely originated from polymer degradation, Smaller TVOC emissions were observed in N(2) atmosphere than in air atmosphere. In particular, larger amounts of the oxygenated compounds, which are generally hazardous and malodorous, were detected in air than in N(2). In addition to the compounds originating from polymer degradation, the compounds originating from the plastic additives were also detected from LDPE and PS. Furthermore, various species of VOCs likely originating from contaminant inseparate polyvinyl chloride (PVC), food residues, cleaning agents, clegreasers, and so on were detected from the waste plastic. Thus, melting waste plastics, as is conducted in recycling facilities, might generate larger amounts of potentially toxic compounds than producing virgin plastics.
  • 水越厚史; 山本尚理; 飯塚淳; 篠原直秀; 藤井実; 山崎章弘; 柳沢幸雄
    環境情報科学学術研究論文集 環境情報科学センター 22 281 - 286 0389-6633 2008/11 [Refereed]
  • Atsushi Mizukoshi; Kazukiyo Kumagai; Naomichi Yamamoto; Miyuki Noguchi; Kazuhiro Yoshiuchi; Hiroaki Kumano; Yukio Yanagisawa
    IAQVEC 2007 Proceedings - 6th International Conference on Indoor Air Quality, Ventilation and Energy Conservation in Buildings: Sustainable Built Environment 1 519 - 522 2007 
    While various VOCs are known to show neurotoxic effects, the detailed mechanisms of VOCs on autonomic nervous system have not been fully understood partly because objective and quantitative measures to indicate neural abnormalities are still under development. Nevertheless, heart rate variability (HRV) has been recently proposed as an indicative measure of the autonomic defect. In this study, we used HRV as an indicative measure of the autonomic defect to relate their values to the personal concentrations of VOCs measured by a real-time VOC monitor. The measurements were conducted to 7 healthy subjects for 24 hours. The results showed HF powers were decreased for 6 subjects when the TVOC concentration changes were high, indicating the suppression of parasympathetic nervous induced by the exposure to VOCs. The present study indicated these real-time monitoring was useful to characterize the trends of VOC exposures and their effects on autonomic nervous system. Application of the present method is expected to lead to diagnosis and cure for the patients such as MCS and sick building syndrome in the future.
  • Atsushi Mizukoshi; Kazukiyo Kumagai; Takako Matsui; Kou Sakabe; Satoshi Ishikawa; Kanji Tsuchimoto; Yukio Yanagisawa
    Japanese journal of clinical ecology 日本臨床環境医学会 15 (1) 58 - 63 0916-9407 2006/06 [Refereed]
     
    化学物質不耐症患者の呼気中化学物質濃度を測定し、健康影響の評価に応用できるかを検討した。調査対象者は健常者6名と化学物質不耐症患者26名、対象者から呼気を約1.0L採取し、加熱脱着ガスクロマトグラフ質量分析計にて6種類の揮発性有機化合物(以下、VOC)を測定した。化学物質不耐症患者の病態評価は問診と神経眼科的検査、アンケート調査により評価した。化学物質不耐症患者の呼気中ベンゼン、p-ジクロロベンゼン、イソプレン、リモネン、トルエンは、それぞれ健常者の値に比較して高い傾向が認められ、このうちトルエン濃度は健常者に比較して2倍の高値を示した(p<0.01)。今後、呼気中VOC測定は、化学物質不耐症患者の病態や生体影響の評価に役立つ可能性を明らかにした。(著者抄録)
  • N Shinohara; A Mizukoshi; Y Yanagisawa
    JOURNAL OF EXPOSURE ANALYSIS AND ENVIRONMENTAL EPIDEMIOLOGY NATURE PUBLISHING GROUP 14 (1) 84 - 91 1053-4245 2004/01 [Refereed]
     
    Multiple chemical sensitivity (MCS) has become a serious problem as a result of airtight techniques in modern construction. The mechanism of the MCS, however, has not been clarified. Responsible chemicals and their exposure levels for patient's hypersensitive reactions need to be identified. We measured the exposure of 15 MCS patients to both carbonyl compounds and volatile organic compounds (VOCs) that may induce hypersensitive reactions. The exposures of those not suffering from MCS (non-MCS individuals) were also measured at the same time. To characterize the chemicals responsible for MCS symptoms, we applied a new sampling strategy for the measurement of carbonyls and VOCs using active and passive sampling methods. The results of our study clearly demonstrated that the chemicals responsible for such hypersensitive reactions varied from patient to patient. Moreover, the concentrations during hypersensitive symptoms, which were apparent in some of the MCS patients, were far below both the WHO and the Japanese indoor guidelines. The average exposure levels of MCS patients within a 7-day period were lower than those of paired non-MCS individuals except for a few patients who were exposed to chemicals in their work places. This result indicates that the MCS patients try to keep away from exposures to the chemical compounds that cause some symptoms.
  • Passive parallel VOCs and ventilation rate sampler
    Yumiko Okuizumi; Kazukiyo Kumagai; Minoru Fujii; Hiroshi Yoshino; Naohide Shinohara; Atsushi Mizukoshi; Yukio Yanagisawa
    Proceedings of Healthy Buildings 2003 475 - 479 2003/12 [Refereed]

Books etc

  • 室内環境学会 (Contributor3-26 二次生成)朝倉書店 2023/09 9784254266528 xiii,439, 7p, 図版8p
  • 大気環境の事典
    水越厚史; 柳沢幸雄 (Contributor4-13 シックハウス症候群)朝倉書店 2019/09
  • 大気環境の事典
    水越厚史 (Contributor3-24 室内発生源)朝倉書店 2019/09 9784254180541
  • アレルギー総合ガイドライン2019
    奥村二郎; 水越 厚史 (Contributor12-6法律面)協和企画 2019/06
  • Yukio Yanagisawa; Hiroshi Yoshino; Satoshi Ishikawa; Mikio Miyata (ContributorChapter 13 Methods for Measurement of Indoor Pollution)CRC Press 2017/01 9781466556348 218 127-138
  • 職業性アレルギー疾患診療ガイドライン2016
    奥村 二郎; 水越 厚史 (Contributor第6章 法律面)協和企画 2016/07 9784877941826
  • 膠原病・リウマチ・アレルギー 研修ノート
    奥村二郎; 水越 厚史 (Contributor第７章 諸制度を使いこなす ２．法律の知識)診断と治療社 2016/04
  • 日本建築学会環境基準 AIJES-A0001-2014 ホルムアルデヒドによる室内空気汚染に関する設計・施工等規準・同解説
    日本建築学会 (Contributor3章, 6章)丸善出版株式会社 2014/03 9784818936232 76
  • VOC排出対策ガイド―基礎から実践・評価法まで―
    環境評価分科会 (Contributor)東京都立産業技術研究センター 2011/10
  • Advanced Topics in Environmental Health and Air Pollution Case Studies
    Naohide Shinohara; Atsushi Mizukoshi; Toshiyuki Kataoka; Koichi Takamine; Masashi Gamo; Yukio Yanagisawa; A.M. Moldoveanu Edi (ContributorDistribution of indoor concentrations and emission sources of formaldehyde in Japanese residences)InTech 2011/08 9789533075259 482 329-338
  • 日本建築学会環境基準 AIJES-A006-2010 総揮発性有機化合物による室内空気汚染防止に関する濃度等規準・同解説
    日本建築学会 (Contributor)丸善株式会社 2010/03 9784818936133 48
  • 日本建築学会環境基準 AIJES-A005-2010 トルエンによる室内空気汚染防止に関する設計・施工等規準・同解説
    日本建築学会 (Contributor)丸善株式会社 2010/03 9784818936126 58
  • カークオスマー 科学技術・環境ハンドブック グリーン・サステイナブルケミストリー
    柳沢幸雄; 水越厚史 (Joint translation44章 室内大気汚染とその対策)丸善株式会社 2009/07 9784621081068 1600 Ⅱ-119-133

Conference Activities & Talks

  • 永吉雅人; 北條祥子; 水越厚史; 黒岩義之
    2023年室内環境学会学術大会  2023/12
  • 環境過敏症分科会 2022 年度活動報告  [Invited]
    北條 祥子; 水越 厚史; 黒岩 義之
    第31回日本臨床環境医学会学術集会  2023/06
  • A Neuroscientist’s Hypothesis of the Pathogenesis of Environmental Hypersensitivity and Future Prospects  [Invited]
    Yoshiyuki Kuroiwa; Toshiaki Hirai; Sachiko Hojo; Atsushi Mizukoshi; Naomi Nakasato; Takahiro Suzuki; Masato Nagayoshi; Tetsuro Yanagida; Shinya Urano; Shumpei Yokota
    The 31st Annual Meeting of The Japanese Society of Clinical Ecology  2023/06
  • Environmental Hypersensitivity in Japan Current Status and Future Prospects from an Epidemiological Perspective  [Invited]
    Sachiko Hojo; Yoshiyuki Kuroiwa; Atsushi Mizukoshi; Kentaro Watai; Masato Nagayoshi; Minoru Osawa; Hideo Ogura; Tetsuya Kondo; Gen Kobashi; Yasuo Haruyama; Naomi Nakasato; Takahiro Suzuki; Xi Lu; Naomi Tsurikisawa; Kou Sakabe
    The 31st Annual Meeting of The Japanese Society of Clinical Ecology  2023/06
  • 化学物質過敏・電磁過敏の合併の疑いがある喘息患者の臨床所見の特徴  [Not invited]
    北條 祥子; 釣木澤 尚実; 金谷 久美子; 水越 厚史; 高木 愛理; 黒岩 義之
    第31回日本臨床環境医学会学術集会  2023/06
  • 中枢神経感作症候群としての環境過敏症 ―化学物質過敏症および自己申告電磁過敏症患者の合併症に関する調査―  [Not invited]
    北條 祥子; 黒岩 義之; 春山 康夫; 水越 厚史; 永吉 雅人; 近藤 哲哉; 中吉 隆之; 小橋 元
    第31回日本臨床環境医学会学術集会  2023/06
  • 児童生徒の環境過敏（香害など）に関する全国規模の実態調査 ―保護者の認識が与える影響―  [Not invited]
    永吉 雅人; 北條 祥子; 水越 厚史; 黒岩 義之
    第31回日本臨床環境医学会学術集会  2023/06
  • 児童生徒の環境過敏（香害など）に関する全国規模の実態調査 ―環境過敏を評価するための簡易版調査票の検討―  [Not invited]
    永吉 雅人; 北條 祥子; 菅原 正則; 水越 厚史; 黒岩 義之
    第31回日本臨床環境医学会学術集会  2023/06
  • 脳科学者から見た環境過敏症の発症メカニズム仮説と今後の展望  [Not invited]
    黒岩 義之; 平井 利明; 北條 祥子; 水越 厚史; 中里 直美; 鈴木 高弘; 永吉 雅人; 柳田 徹郎; 浦野 真弥; 横田 俊平
    第31回日本臨床環境医学会学術集会  2023/06
  • 環境過敏症・自己免疫疾患・癌・生活習慣病：有病率の性差から何が見えてくるのか  [Not invited]
    黒岩 義之; 平井 利明; 北條 祥子; 水越 厚史; 中里 直美; 鈴木 高弘; 永吉 雅人; 柳田 徹郎; 浦野 真弥; 横田 俊平
    第31回日本臨床環境医学会学術集会  2023/06
  • 環境と医学の接点：物理環境、化学環境、生物環境、心理社会的環境の健康との関わり  [Not invited]
    黒岩 義之; 平井 利明; 北條 祥子; 水越 厚史; 中里 直美; 鈴木 高弘; 永吉 雅人; 柳田 徹郎; 浦野 真弥; 横田 俊平
    第31回日本臨床環境医学会学術集会  2023/06
  • 水越 厚史; 北條 祥子; 東 賢一; 中間 千香子; 奥村 二郎
    第31回日本臨床環境医学会学術集会  2023/06
  • 治療薬の処方履歴、薬剤への不耐性から見えてくる脳脊髄液漏出症患者の臨床像  [Not invited]
    中里 直美; 黒岩 義之; 北條 祥子; 鈴木 高弘; 水越 厚史; 平井 利明; 横田 俊平; 菅野 洋; 篠永 正道
    第31回日本臨床環境医学会学術集会  2023/06
  • 脳脊髄液減少症患者の電磁過敏反応に関する検討  [Not invited]
    鈴木 高弘; 北條 祥子; 中里 直美; 黒岩 義之; 水越 厚史; 篠永 正道
    第31回日本臨床環境医学会学術集会  2023/06
  • 地域住民を対象としたスマートウォッチを用いた健康管理の取り組みと課題について  [Not invited]
    中間 千香子; 髙井 逸史; 水越 厚史
    第31回日本臨床環境医学会学術集会  2023/06
  • 水越厚史; 東賢一
    2023年室内環境学会シンポジウム： 新型コロナウイルスの感染対策に有用な室内環境研究の最新情報  2023/03
  • 水越 厚史; 北條 祥子; 東 賢一; 中間 千香子; 奥村 二郎
    第93回日本衛生学会学術総会  2023/03
  • Report on Electromagnetic Hypersensitivity Reactions Associated with 20 patients with Cerebrospinal Fluid Hypovolemia  [Not invited]
    Takahiro SUZUKI; Sachiko HOJO; Naomi NAKAZATO; Atsushi MIZUKOSHI; Masamichi SHINONAGA; Hiroshi KANNO; Yoshiyuki KUROIWA
    Proceedings of 2022 Annual Meeting of the Society of Indoor Environment, Japan  2022/12
  • Environmental Hypersensitivity Symptoms in Cerebrospinal Fluid Hypovolemia as Learned From a Pharmacist Survey.  [Not invited]
    Naomi NAKAZATO; Sachiko HOJO; Takahiro SUZUKI; Atsushi MIZUKOSHI; Masamichi SHINONAGA; Hiroshi KANNO; Toshiaki HIRAI; Yoshiyuki KUROIWA
    Proceedings of 2022 Annual Meeting of the Society of Indoor Environment, Japan  2022/12
  • Yoshiyuki KUROIWA; Toshiaki HIRAI; Shumpei YOKOTA; Atsushi MIZUKOSHI; Naomi NAKAZATO; Takahiro SUZUKI; Sachiko HOJO
    Proceedings of 2022 Annual Meeting of the Society of Indoor Environment, Japan  2022/12
  • Yoshiyuki KUROIWA; Toshiaki HIRAI; Shumpei YOKOTA; Atsushi MIZUKOSHI; Naomi NAKAZATO; Takahiro SUZUKI; Sachiko HOJO
    Proceedings of 2022 Annual Meeting of the Society of Indoor Environment, Japan  2022/12
  • Comparative Survey of Lifestyle and Health Status of University Students Before and After COVID-19  [Not invited]
    Sachiko HOJO; Masanori SUGAWARA; Momoka KOYAMA; Atsushi MIZUKOSHI; Takao YAMANAKA; Yoshiyuki KUROIWA
    Proceedings of 2022 Annual Meeting of the Society of Indoor Environment, Japan  2022/12
  • Sachiko HOJO; Naomi NAKAZATO; Atsushi MIZUKOSHI; Takahiro SUZUKI; Masanori SUGAWARA; Takao YAMANAKA; Yoshiyuki KUROIWA
    Proceedings of 2022 Annual Meeting of the Society of Indoor Environment, Japan  2022/12
  • 生活の場に溢れる化学物質や「香り」について考える 空気汚染の健康影響と予防  [Invited]
    水越厚史
    第29回環境学校  2022/11
  • 水越厚史; 奥村二郎; 東賢一
    第81回 近畿大学医学会学術講演会  2022/07
  • 北條 祥子; 水越 厚史; 黒岩 義之
    第30回日本臨床環境医学会学術集会  2022/06
  • コロナ禍における大学生の生活スタイルと環境過敏関連症状に関する実態調査  [Not invited]
    菅原 正則; 北條 祥子; 水越 厚史; 小山 桃花
    第30回日本臨床環境医学会学術集会  2022/06
  • 化学物質過敏症患者の嗅覚特性：同定能力とにおいの種類の告知が 評価に及ぼす影響  [Not invited]
    萬羽 郁子; 東 賢一; 東 実千代; 水越 厚史; 谷川 真理; 内山 巌雄
    第30回日本臨床環境医学会学術集会  2022/06
  • 黒岩 義之; 平井 利明; 水越 厚史; 中里 直美; 鈴木 高弘; 横田 俊平; 北條 祥子
    第30回日本臨床環境医学会学術集会  2022/06
  • 薬剤師による脳脊髄液減少症患者の環境過敏反応に関する調査（その 2） 〜電磁過敏反応を中心に〜  [Not invited]
    中里 直美; 北條 祥子; 鈴木 高弘; 篠永 正道; 菅野 洋; 水越 厚史; 平井 利明; 横田 俊平; 黒岩 義之
    第30回日本臨床環境医学会学術集会  2022/06
  • 薬剤師による脳脊髄液減少症患者の環境過敏反応に関する調査（その１） 〜化学物質過敏反応を中心に〜  [Not invited]
    中里 直美; 北條 祥子; 鈴木 高弘; 篠永 正道; 菅野 洋; 水越 厚史; 平井 利明; 横田 俊平; 黒岩 義之
    第30回日本臨床環境医学会学術集会  2022/06
  • 黒岩 義之; 平井 利明; 水越 厚史; 中里 直美; 鈴木 高弘; 横田 俊平; 北條 祥子
    第30回日本臨床環境医学会学術集会  2022/06
  • 化学物質過敏用問診票（QEESI）と電磁過敏評価用問診票（EHS 問診票）を用いた 脳脊髄液減少症患者の環境過敏反応に関する調査  [Not invited]
    鈴木 高弘; 北條 祥子; 中里 直美; 水越 厚史; 菅野 洋; 篠永 正道; 平井 利明; 黒岩 義之
    第30回日本臨床環境医学会学術集会  2022/06
  • 問診票得点と臨床所見に基づく化学物質過敏症・電磁過敏症とアレルギー疾患の比較  [Not invited]
    北條 祥子; 水越 厚史; 金谷 久美子; 宮田 幹夫; 小倉 英郎; 釣木澤 尚実; 押方 智也子; 渡井 健太; 山中 隆夫; 小澤 麻紀; 相場 節也; 角田 和彦; 黒岩 義之
    第30回日本臨床環境医学会学術集会  2022/06
  • 北條 祥子; 水越 厚史; 中里 直美; 鈴木 高弘; 角田 和彦; 西影 京子; 渡井 健太郎; 山中 隆夫; 近藤 哲哉; 平井 利幸; 黒岩 義之
    第30回日本臨床環境医学会学術集会  2022/06
  • 水越 厚史; 北條 祥子; 東 賢一; 中間 千香子; 黒岩 義之; 奥村 二郎
    第30回日本臨床環境医学会学術集会  2022/06
  • Atsushi Mizukoshi; Jiro Okumura; Kenichi Azuma
    The 17th International Conference of the International Society of Indoor Air Quality & Climate  2022/06
  • Atsushi Mizukoshi; Jiro Okumura; Kenichi Azuma
    The 92nd Annual Meeting of the Japanese Society for Hygiene  2022/03
  • 水越厚史; 奥村二郎; 東賢一
    第80回日本公衆衛生学会総会  2021/12
  • Atsushi Mizukoshi; Jiro Okumura; Kenichi Azuma
    Healthy Buildings America 2021  2022/01
  • Survey on University Students' Conditions for Environmental Hypersensitivity Using QEESI/EHS Questionnaires  [Not invited]
    Momoka Koyam; Sachiko Hojo; Atsushi Mizukoshi; Masanori Sugawara
    2021 Annual Meeting of the Society of Indoor Environment, Japan  2021/12
  • Characteristics of Olfactory Identification Ability in Multiple Chemical Sensitivity patients  [Not invited]
    Ikuko Bamba; Kenichi Azuma; Michiyo Azuma; Atsushi Mizukoshi; Mari Tanigawa; Iwao Uchiyama
    2021 Annual Meeting of the Society of Indoor Environment, Japan  2021/12
  • Air exchange rates in buildings that are expected to be used as shelters during disasters  [Not invited]
    Working Group on COVID-19 Infection Control, Society of Indoor Environment, Japan; Naohide Shinohara; Naoki Kagi; Hoon Kim; Yoshika Sekine; Masafumi Oikawa; Kouichi Tatsu; Kazuhiro Hashimoto; Jun Sakaguchi; Yasuhiko Ota; Akihiro Nagata; Futoshi Yoshimura; Etsuo Kimura
    2021 Annual Meeting of the Society of Indoor Environment, Japan  2021/12
  • 篠原直秀; 青柳玲児; 池田四郎; 石坂閣啓; 光崎 純; 中井里史; 野口美由貴; 水越厚史
    第62回 大気環境学会年会  2021/09
  • Atsushi Mizukoshi; Kenichi Azuma
    Architecture Institute of Japan  2021/09
  • 脳脊髄液減少症患者の薬剤師調査報告 ～院内問診票と服用薬調査から見た視床下部症候群との関連性を中心に～  [Not invited]
    中里 直美; 黒岩 義之; 水越 厚史; 菅野 洋; 平井 利明; 横田 俊平; 鈴木 高弘; 北條 祥子
    第29回日本臨床環境医学会学術集会  2021/06
  • 世界共通問診票を用いた脳脊髄液減少症患者の症状・環境過敏反応に関する調査  [Not invited]
    鈴木 高弘; 中里 直美; 菅野 洋; 黒岩 義之; 水越 厚史; 北條 祥子
    第29回日本臨床環境医学会学術集会  2021/06
  • 黒岩 義之, 平井 利明, 横田 俊平, 中里 直美, 水越 厚史, 鈴木 高弘, 山田 昌興, 北條 祥子
    第29回日本臨床環境医学会学術集会  2021/06
  • A survey report on sensory and immune hypersensitivity in cerebrospinal fluid hypovolemia from a pharmacist’s perspective  [Not invited]
    Naomi Nakazato; Sachiko Hojo; Takahiro Suzuki; Atsushi Mizukoshi; Masamichi Shinonaga; Hiroshi Kanno; Toshiaki Hirai; Shumpei Yokota; Yoshiyuki Kuroiwa
    2020 Annual meeting of the society of indoor environment, Japan  2020/12
  • Environmental hypersensitivity is a condition in which emergency-type hypothalamic activity is activated even in normal conditions  [Not invited]
    Yoshiyuki Kuroiwa; Toshiaki Hirai; Naomi Nakazato; Takahiro Suzuki; Atsushi Mizukoshi; Masamichi Shinonaga; Hiroshi Kanno; Shumpei Yokota; Sachiko Hojo
    2020 Annual meeting of the society of indoor environment, Japan  2020/12
  • Survey of environmental hypersensitivity using QEESI and EHS questionnaire (Comparison of scores among multiple chemical sensitivity patients, electromagnetic hypersensitivity complainants, patients with cerebrospinal fluid hypovolemia, asthma patients, atopic dermatitis patients, and the general population)
    Sachiko Hojo, Atsushi Mizukoshi, Takahiko Katoh, Mikiko Tokiya, Yoshiyuki Kuroiwa
    2020 Annual meeting of the society of indoor environment, Japan  2020/12
  • A survey of environmental hypersensitivity reactions in patients with cerebrospinal fluid hypovolemia using the universal questionnaire (Report 2)  [Not invited]
    Takahiro Suzuki; Sachiko Hojo; Naomi Nakazato; Atsushi Mizukoshi; Yoshiyuki Kuroiwa; Hiroshi Kanno; Masamichi Shinonaga; Noriyasu Hirasawa
    2020 Annual meeting of the society of indoor environment, Japan  2020/12
  • 環境過敏症：環境過敏を評価する疫学ツールとしての国際共通問診票（日本語簡易版）の開発  [Invited]
    水越 厚史
    第73回日本自律神経学会総会  2020/11
  • Atsushi Mizukoshi; Naohide Shinohara; Kenichi Azuma; Chikako Nakama; Jiro Okumura
    Indoor Air 2020  2020/11
  • 水越厚史; 中間千香子; 奥村二郎; 東 賢一
    第61回 大気環境学会年会室内環境分科会  2020/09
  • Activity report (2019) on subcommittee of Environmental Hypersensitivity  [Invited]
    Sachiko HOJO; Atsushi MIZUKOSHI; Masahiro TOKUMURA; Miwako NYUI
    2019 Annual Meeting of the Society of Indoor Environment, Japan  2019/12
  • Research on questionnaires for environmental intolerance assessment  [Not invited]
    Atsushi MIZUKOSHI; Sachiko HOJO; Kenichi AZUMA; Chikako NAKAMA; Jiro OKUMURA
    2019 Annual Meeting of the Society of Indoor Environment、Japan  2019/12
  • 地方自治体と検疫所の協力・連携に係る現状や制度上の課題及びその論点  [Invited]
    奥村二郎; 東 賢一; 水越厚史; 中間千香子
    第78回日本公衆衛生学会総会  2019/10
  • Environmental Chemical Sensitizers ; Evaluation of the legal and policy issues  [Invited]
    Jiro Okumura; Kenichi Azuma; Atsushi Mizukoshi
    The 78th Annual Meeting of Japanese Society of Public Health  2019/10
  • Sensing in in a simulated aircraft cabin environment  [Invited]
    Atsushi Mizukoshi; Kenichi Azuma; Shigehiro Sugiyama; Daisuke Tanaka; Masashi Inoue; Masahiro Tokumura; Jiro Okumura
    The 60th Annual Meeting of Japan Society for Atmospheric Environment  2019/09
  • “環境過敏度評価用簡略版問診票”の作成  [Invited]
    水越 厚史; 北條祥子
    合同研究会2019（生活環境と健康研究会他）  2019/09
  • Temporal change of formaldehyde concentration in outdoor environments  [Not invited]
    Atsushi Mizukoshi; Akira Nagano; Kenichi Azuma; Jiro Okumura
    ISES ISIAQ 2019  2019/08
  • QEESIのMCS患者スクリーニング用新基準値によるMCS患者、喘息患者、EHS有訴者、一般人の比較  [Not invited]
    水越厚史; 北條祥子; 東賢一; 奥村二郎; 水城まさみ; 宮田幹夫; 小倉英郎; 釣木澤尚実; 押方智也子; 加藤貴彦; 角田和彦; 西影京子; 坂部貢
    第28回日本臨床環境医学会学術集会  2019/06
  • 脳脊髄液減少症と環境過敏反応（化学物質過敏反応/電磁過敏反応）に関連性に関する調査  [Not invited]
    鈴木高弘; 北條祥子; 中里直美; 水越厚史; 野村彩衣; 菅野洋; 平澤典保; 篠永正道
    第28回日本臨床環境医学会学術集会  2019/06
  • Evaluation of the legal and policy issues associated with the treatment of allergic disorders by environmental chemicals in Japan.  [Not invited]
    Jiro Okumura; Kenichi Azuma; Atsushi Mizukoshi
    The 68th Annual Meeting of Japanese Society of Allergology  2019/06
  • フォトフェントン反応による気中2-エチル-1-ヘキサノールの除去  [Not invited]
    水越 厚史; 徳村 雅弘; 東 賢一; 奥村 二郎
    平成30年室内環境学会学術大会  2018/12
  • 塩ビシートからのDEHPのハウスダストへの移行 ～PFSを用いた移行速度と実環境中ダスト濃度～  [Not invited]
    篠原 直秀; 内野 加奈子; 水越 厚史
    平成30年室内環境学会学術大会  2018/12
  • QEESI とEHS 問診票を用いた環境過敏症患者と一般人の自覚症状・過敏反応の比較  [Not invited]
    北條祥子; 水越厚史; 水城まさみ; 宮田幹夫; 加藤貴彦; 東 賢一; 小倉英郎; 乳井美和子; 坂部 貢
    平成30年室内環境学会学術大会  2018/12
  • QEESI と統計データからみた日本人の日常化学物質曝露状況の変化と今後の課題  [Invited]
    水越 厚史
    平成30年室内環境学会学術大会  2018/12
  • Activity report (2019) on subcommittee of Environmental Hypersensitivity  [Not invited]
    Sachiko HOJO; Atsushi MIZUKOSHI; Masahiro TOKUMURA; Miwako NYUI
    平成30年室内環境学会学術大会  2018/12
  • 環境化学物質及びそれによるアレルギー疾患に対する行政施策について  [Not invited]
    奥村二郎; 東 賢一; 水越厚史
    第77回日本公衆衛生学会総会  2018/10
  • 検疫に関係する我が国における法律や制度及びその方向性について  [Invited]
    奥村二郎; 東 賢一; 水越厚史; 柏樹悦郎
    第77回日本公衆衛生学会総会  2018/10
  • Trends of scented products in indoor environment and odor measurement methods by olfaction  [Invited]
    Atsushi Mizukoshi; Kenichi Azuma; Jiro Okumura
    The 59th Annual Meeting of Japan Society for Atmospheric Environment  2018/09
  • Reaction between ozone and limonene under reduced pressure conditions simulating an aircraft cabin environment  [Not invited]
    Atsushi Mizukoshi; Kenichi Azuma; Shigehiro Sugiyama; Daisuke Tanaka; Masashi Inoue; Masahiro Tokumura; Jiro Okumura
    Indoor Air 2018  2018/07
  • 日本人の日常生活からの化学物質曝露状況の10年間の変化 ― QEESIのMasking Indexと統計データを比較して ―  [Not invited]
    水越厚史; 北條祥子; 東 賢一; 奥村二郎; 石川 哲; 宮田幹夫; 水城まさみ; 小倉英郎; 乳井美和子; 坂部 貢
    第27回日本臨床環境医学会学術集会  2018/07
  • 環境化学物質によるアレルギー疾患に対する、我が国の行政施策について  [Invited]
    奥村 二郎; 東 賢一; 水越 厚史
    第76回日本公衆衛生学会総会  2017/11
  • 都市部における戸建住居や集合住宅への診療所からの往診等に関する検討  [Not invited]
    奥村 二郎; 東 賢一; 水越 厚史
    第76回日本公衆衛生学会総会  2017/10
  • QEESIの化学物質不耐症患者スクリーニング用新基準値の検討  [Not invited]
    水越 厚史; 東 賢一; 奥村 二郎; 北條 祥子
    第76回日本公衆衛生学会総会  2017/10
  • Measurement of reaction products of emitted gas from melted plastic pellets and ambient ozone  [Not invited]
    Kenichi Azuma; Miyuki Noguchi; Akihiro Yamasaki; Masahiro Tokumura; Jiro Okumra
    The 58th Annual Meeting of Japan Society for Atmospheric Environment  2017/09
  • 北條祥子; 水越厚史; 宮田幹夫; 水城まさみ; 大友守; 小倉英郎; 釣木澤尚実; 押方智也子; 坂部貢; 東賢一; 石川哲
    第26回臨床環境医学会学術集会  2017/06
  • 水越厚史; 北條祥子; 東賢一; 奥村二郎; 宮田幹夫; 坂部貢; 水城まさみ; 小倉英郎; 大友守; 石川哲
    第26回臨床環境医学会学術集会  2017/06
  • たばこ煙および臭気除去システムの開発 ―その 5 事務所ビルの喫煙ブースでの長期測定  [Not invited]
    佐伯寅彦; 岩間裕樹; 穴井俊博; 湯懐鵬; 津島健; 野口美由貴; 水越厚史; 柳沢幸雄
    平成28年室内環境学会学術大会  2016/12
  • Reaction analysis of products in an aircraft cabin and ozone gas  [Not invited]
    Atsushi Mizukoshi; Azuma Kenichi; Shigehiro Sugiyama; Daisuke Tanaka; Masashi Inoue; Masahiro Tokumura; Jiro Okumura
    平成28年室内環境学会学術大会  2016/12
  • 本態性環境不耐症に関する質問紙調査－化学物質と電磁界への不耐症と既往歴との関係－  [Not invited]
    水越厚史; 東賢一; 奥村二郎; 北條祥子
    第75回日本公衆衛生学会総会  2016/10
  • 篠原直秀; 岡崎友紀代; 水越厚史; 若松伸司
    大気環境学会年会講演要旨集  2016/08
  • Investigation of reaction products of ozone and organic compounds in a simulated aircraft cabin  [Not invited]
    Atsushi Mizukoshi; Kenichi Azuma; Daisuke Tanaka; Masashi Inoue; Shinsuke Usui; Jiro Okumura
    THE 14TH INTERNATIONAL CONFERENCE OF INDOOR AIR QUALITY AND CLIMATE  2016/07
  • QEESI問診票およびEHS問診票を用いた調査（その３）―化学物質過敏性と電磁過敏性を同時評価する問診票作成―  [Not invited]
    水越厚史; 東賢一; 奥村二郎; 水城まさみ; 宮田幹夫; 小倉英郎; 熊野宏昭; 坂部貢; 青木真一; 今井奈妙; 須藤京子; 角田和彦; 宮田英威; 乳井美和子; 吉富邦明; 徳村雅弘; 野口美由貴; 北條祥子
    第25回日本臨床環境医学会学術集会  2016/06
  • QEESI問診票およびEHS問診票を用いた調査（その２）―化学物質過敏症患者、喘息患者、自己申告電磁過敏症有訴者、および一般人の症状・反応の比較―  [Not invited]
    水越厚史; 水城まさみ; 宮田幹夫; 大友守; 小倉英郎; 釣木澤尚実; 押方智也子; 熊野宏昭; 坂部貢; 青木真一; 東賢一; 奥村二郎; 金谷久美子; 今井奈妙; 宮田英威; 北條祥子
    第25回日本臨床環境医学会学術集会  2016/06
  • QEESI問診票およびEHS問診票を用いた調査（その１）―化学物質過敏症専門医による症状経過からの患者のタイプ分類―  [Not invited]
    北條祥子; 水越厚史; 水城まさみ; 宮田幹夫; 大友守; 小倉英郎; 坂部貢; 東賢一; 奥村二郎; 角田和彦; 乳井美和子; 熊野宏昭
    第25回日本臨床環境医学会学術集会  2016/06
  • 50ヘルツ磁場に曝露されたマクロファージにおけるスーパーオキシドアニオン産生  [Not invited]
    西垣千尋; 中山希祐; 中村文; 水越厚史; 北條祥子; 宮田英威
    早稲田大学応用脳科学研究所シンポジウム2016  2016/03
  • QEESI及びEHS問診票を合体簡略化した化学物質過敏性および電磁過敏性を評価するための問診票作成の検討  [Not invited]
    水越 厚史; 熊野 宏昭; 辻内 琢也; 宮田 英威; 北條 祥子
    早稲田大学応用脳科学研究所シンポジウム2016  2016/03
  • Investigation of reaction products of ozone and organic compounds in a simulated aircraft cabin environment  [Not invited]
    Atsushi Mizukoshi; Kenichi Azuma; Daisuke Tanaka; Masashi Inoue; Jiro Okumura
    平成27年室内環境学会学術大会  2015/12
  • Development of ETS and Odor Removal System IV Field Study of Smoking Booth in an Office Building  [Not invited]
    Torahiko SAEKI; Hiroki IWAMA; Toshihiro ANAI; Huaipeng TANG; Sakurako YAMAKITA; Yuu SAKAMOTO; Takeshi TSUSHIMA; Miyuki NOGUCHI; Atsushi MIZUKOSHI; Yukio YANAGISAWA
    平成27年室内環境学会学術大会  2015/12
  • 平成27年度室内環境学会賞・論文賞 受賞講演「省エネルギーとシックビル対策を配慮した室内CO2及びTVOC濃度を指標とする空調制御の検討」  [Invited]
    水越厚史; 野口美由貴; 山本総一朗; 川上梨沙; 大塚俊裕; 山口一; 柳沢幸雄
    平成27年室内環境学会学術大会  2015/12
  • 消費者製品に含有されるSVOCの皮膚移行、経皮吸収に関する文献調査  [Not invited]
    水越厚史; 東賢一; 萬羽郁子; 奥村二郎
    第24回日本臨床環境医学会学術集会  2015/06
  • Review of dermal exposure factors concerning the phtalates in consumer products  [Not invited]
    Atsushi Mizukoshi; Kenichi Azuma; Ikuko Bamba; Jiro Okumura
    Healthy Buildings Europe 2015  2015/05
  • 日常生活における化学物質過敏症患者のVOC曝露と心拍変動モニタリング  [Not invited]
    水越厚史; 熊谷一清; 山本尚理; 野口美由貴; 吉内一浩; 熊野宏昭; 小沢学; 松井孝子; 坂部貢; 柳沢幸雄
    早稲田大学応用脳科学研究所シンポジウム2015  2015/03
  • 消費者製品に含有されるSVOC の経皮吸収の暴露係数に関する調査  [Not invited]
    水越厚史; 東賢一
    平成26年室内環境学会学術大会  2014/12
  • たばこ煙および臭気除去システムの開発―その３ 据置型喫煙ブースを設置した模擬オフィスの音環境の評価  [Not invited]
    佐伯寅彦; 白木秀児; 前田康博; 湯懐鵬; 野口美由貴; 水越厚史; 柳沢幸雄
    平成26年室内環境学会学術大会  2014/12
  • 化学物質過敏症患者の揮発性有機化合物への曝露と症状との関係について  [Not invited]
    水越厚史; 萬羽郁子; 東賢一; 奥村二郎
    第73回近畿大学医学会学術講演会  2014/07
  • 飯田孝彦; 小沼ルミ; 浜野智子; 水越厚史; 瓦田研介
    東京都立産業技術研究センター研究成果発表会要旨集  2014/06
  • 北條祥子; 秋山一男; 水城まさみ; 宮田幹夫; 石川哲; 坂部貢; 相澤好治; 小倉英郎; 山中隆夫; 角田和彦; 吉野博; 釣木澤尚実; 長谷川眞紀; 大友守; 押方智也子; 水越厚史; 今井奈妙; 加藤貴彦; 木俣肇; 辻内琢也; 熊野宏昭
    第23回日本臨床環境医学会学術集会  2014/06
  • 北條祥子; 秋山一男; 水城まさみ; 小倉英郎; 宮田幹夫; 石川哲; 坂部貢; 釣木澤尚実; 押方智也子; 長谷川眞紀; 大友守; 今井奈妙; 土器屋美貴子; 乳井美和子; 角田和彦; 木俣肇; 加藤貴彦; 五十嵐公英; 井上博之; 青木真一; 高塚俊治; 近藤加代子; 吉富邦明; 水越厚史; 辻内琢也; 宮田英威; 熊野宏昭
    第23回日本臨床環境医学会学術集会  2014/06
  • 小沼ルミ; 瓦田研介; 水越厚史; 飯田孝彦; 吉田誠
    公益社団法人日本木材保存協会 第30回年次大会  2014/05
  • 小沼ルミ; 瓦田研介; 水越厚史; 飯田孝彦; 吉田誠
    第64回日本木材学会大会  2014/03
  • 野口美由貴; 水越厚史; 柳沢幸雄; 山崎章弘
    平成25年室内環境学会学術大会  2013/12
  • Kensuke Kawarada; Tomoko Hamano; Atsushi Mizukoshi; Rumi Konuma; Takahiko Iida; Hideaki Korai
    International Conference on Wood Adhesives 2013  2013/10
  • 小沼ルミ; 瓦田研介; 水越厚史; 飯田孝彦; 浜野智子; 吉田誠
    日本きのこ学会第17 回大会  2013/09
  • 水越厚史; 飯田孝彦; 小沼ルミ; 濱野智子; 瓦田研介; 野口美由貴; 柳沢幸雄
    Separation Sciences 2013  2013/08
  • Toxicity Evaluation of Organophosphate Flame Retardants in terms of Cholinesterase Inhibition  [Not invited]
    Miyuki Noguchi; Atsushi Mizukoshi; Akira Nishimura; Yukio Yanagisa; Akihiro Yamasaki
    Environment and Health  2013/08
  • Risk assessments of TVOC compositions in new buildings  [Not invited]
    Atsushi Mizukoshi; Takahiko Iida; Rumi Konuma; Tomoko Hamano; Kensuke Kawarada; Miyuki Noguchi; Yukio Yanagisawa
    Environment and Health  2013/08  Basel, Switzerland
  • 小沼ルミ; 水越厚史; 飯田孝彦; 浜野智子; 瓦田研介
    東京都立産業技術研究センター平成25年度研究成果発表会  2013/06
  • 水越厚史; 瓦田研介; 田井洋雄; 小林秀樹; 冨士森みつ; 下垣彰; 安城泰雄
    東京都立産業技術研究センター平成25年度研究成果発表会  2013/06
  • 佐々木直里; 中澤亮二; 田中真美; 水越厚史
    東京都立産業技術研究センター平成25年度研究成果発表会  2013/06
  • 染川正一; 井上潤; 萩原利哉; 藤井恭子; 水越厚史; 小島正行; 篠田勉
    東京都立産業技術研究センター平成25年度研究成果発表会  2013/06
  • 浜野智子; 飯田孝彦; 小沼ルミ; 水越厚史; 瓦田研介
    第63回日本木材学会大会  2013/03
  • 萩原利哉; 水越厚史; 染川正一
    環境科学会年会プログラム  2012/09
  • 水越厚史; 萩原利哉; 染川正一; 井上潤; 小島正行
    環境科学会2012年会  2012/09
  • NOGUCHI Miyuki; MIZUKOSHI Atsushi; MURAKAMI Eizo; SAKAI Yuka; SHIMANAKA Ayumi; YAMASAKI Akihiro
    学術講演会論文集  2012/09
  • Kawakami Risa; Yamagchi Makoto; Otsuka Toshihiro; Yanagisawa Yukio; Noguchi Miyuki; Mizukoshi Atsushi
    学術講演会論文集  2012/09
  • SHINOHARA Naohide; YANAGI U; TOKUMURA Masahiro; MIZUKOSHI Atsushi; YOSHINO Hiroshi
    2012年度日本建築学会大会  2012/09
  • 瓦田研介; 浜野智子; 水越厚史; 飯田孝彦; 小沼ルミ; 高麗秀昭
    東京都立産業技術研究センター平成24年度研究成果発表会  2012/06
  • Phtalate emissions from building materials  [Not invited]
    Naohide Shinohara; Atsushi Mizukoshi
    Healthy Buildings 2012  2012
  • 野口美由貴; 水越厚史; 前田康博; 佐伯寅彦; 湯懐鵬; 柳沢幸雄
    平成23年度室内環境学会学術大会  2011/12
  • 前田康博; 佐伯寅彦; 湯懐鵬; 野口美由貴; 水越厚史; 柳沢幸雄
    平成23年度室内環境学会学術大会  2011/12
  • 篠原直秀; 徳村雅弘; 風間美冴; 吉野寛之; 畑山瑠莉香; 落合聖史; 水越厚史; 柳宇
    平成23年度室内環境学会学術大会  2011/12
  • 落合聖史; 野口美由貴; 水越厚史; 柳沢幸雄
    平成23年度室内環境学会学術大会  2011/12
  • 萩原利哉; 小島正行; 染川正一; 藤井恭子; 水越厚史
    東京都立産業技術研究センター平成23年度研究成果発表会  2011/11
  • 水越厚史; 井上潤; 篠田勉
    東京都立産業技術研究センター平成23年度研究成果発表会  2011/11
  • 水越厚史; 野口美由貴; 徳村雅弘; 石塚祐輔; 和田友布子; 柳沢幸雄
    東京都立産業技術研究センター平成23年度研究成果発表会  2011/11
  • 野口美由貴; 水越厚史; 柳沢幸雄
    大気環境学会年会  2011/09
  • 宇佐美友理; 和田友布子; 徳村雅弘; 八巻高子; 水越厚史; 野口美由貴; 山崎章弘; 柳沢幸雄
    化学工学会第76年会  2011/03
  • 和田友布子; 宇佐美友理; 徳村雅弘; 八巻高子; 水越厚史; 野口美由貴; 山崎章弘; 柳沢幸雄
    化学工学会第76年会  2011/03
  • 西村知; 水越厚史; 徳村雅弘; 野口美由貴; 山崎章弘; 柳沢幸雄
    化学工学会第76年会  2011/03
  • 石塚祐輔; 野口美由貴; 水越厚史; 酒井裕香; 山崎章弘; 柳沢幸雄
    化学工学会第76年会  2011/03
  • フォトフェントン反応を用いた新規空気清浄法の開発  [Not invited]
    宇佐美友理; 和田友布子; 徳村雅弘; 水越厚史; 野口美由貴; 柳沢幸雄
    第11回グリーン・サステイナブルケミストリーシンポジウム  2011
  • Innovative air cleaning method using photo-Fenton reaction in ultrasonic mist  [Not invited]
    Yuri Usami; Masahiro Tokumura; Atsushi Mizukoshi; Miyuki Noguchi; Yukio Yanagisawa
    The 3rd Asia-Oceania Conference on Green & Sustainable Chemistry  2011
  • Novel air cleaning method using photo-Fenton reaction in ultrasonic mist  [Not invited]
    Yuri Usami; Yuko Wada; Masahiro Tokumura; Atsushi Mizukoshi; Miyuki Noguchi; Yukio Yanagisawa
    The 1st international symposium on Multiscale Multiphase Process Engineering  2011
  • Removal of VOC from indoor environment using photo Fenton reaction  [Not invited]
    Masahiro Tokumura; Yuko Wada; Yuri Usami; Atsushi Mizukoshi; Miyuki Noguchi; Yukio Yanagisawa
    The 1st international symposium on Multiscale Multiphase Process Engineering  2011
  • Generation of fine particles and secondary oxidation compounds during terpenes ozonolysis  [Not invited]
    Miyuki Noguchi; Yusuke Ishizuka; Atsushi Mizukoshi; Yuka Sakai; Akihiro Yamasaki; Yukio Yanagisawa
    Indoor Air 2011  2011
  • Concentration and constitution of TVOC in recent new building  [Not invited]
    Atsushi Mizukoshi; Noguchi Miyuki; Yamki Takako; Yanagisawa Yukio
    Indoor Air 2011  2011
  • 柳沢幸雄; 水越厚史; 八巻高子; 野口美由貴
    平成22年度室内環境学会学術大会  2010/12
  • 野口美由貴; 水越厚史; 八巻高子; 村上栄造; 堀雅宏; 柳沢幸雄
    平成22年度室内環境学会学術大会  2010/12
  • 小林徳和; 湯懐鵬; 野口美由貴; 水越厚史; 柳沢幸雄
    平成22年度室内環境学会学術大会  2010/12
  • 水越厚史; 篠原直秀; 野口美由貴; 内富男; 柳沢幸雄
    平成22年度室内環境学会学術大会  2010/12
  • 徳村雅弘; 宇佐美友理; 和田友布子; 八巻高子; 水越厚史; 野口美由貴; 柳沢幸雄
    平成22年度室内環境学会学術大会  2010/12
  • 八巻高子; 野口美由貴; 水越厚史; 柳沢幸雄
    平成22年度室内環境学会学術大会  2010/12
  • 篠原直秀; 水越厚史; 野口美由貴; 柳澤幸雄
    平成22年度室内環境学会学術大会  2010/12
  • 石塚祐輔; 野口美由貴; 水越厚史; 酒井裕香; 山崎章弘; 柳沢幸雄
    平成22年度室内環境学会学術大会  2010/12
  • 野口美由貴; 水越厚史; 小林徳和; 湯懐鵬; 柳沢幸雄
    平成22年度室内環境学会学術大会  2010/12
  • 水越厚史; 木下稔夫; 野口美由貴; 齋藤京子; 柳沢幸雄
    第51回大気環境学会年会  2010/09
  • 野口美由貴; 八巻高子; 水越厚史; 柳沢幸雄
    第51回大気環境学会年会  2010/09
  • 水越厚史; 野口美由貴; 飯塚淳; 井上靖雄; 齋藤京子; 柳沢幸雄
    第19回日本臨床環境医学会学術集会  2010/07
  • 野口美由貴; 水越厚史; 八巻高子; 柳沢幸雄
    第19回日本臨床環境医学会学術集会  2010/07
  • 水越厚史; 木下稔夫; 野口美由貴; 齋藤京子; 柳沢幸雄
    東京都立産業技術研究センター平成22年度研究発表会  2010/06
  • 石崎浩明; 飯塚淳; 水越厚史; 野口美由貴; 山崎章弘; 柳沢幸雄
    化学工学会第75年会  2010/03
  • 塗装シミュレータによる塗装工程ごとのVOC成分の調査  [Not invited]
    水越厚史; 木下稔夫; 野口美由貴; 齋藤京子; 柳沢幸雄
    千葉県産業支援技術研究所平成22年度研究成果発表会  2010
  • Exposure assessment of hazardous chemical during running along a road  [Not invited]
    Naohide Shinohara; Atsushi Mizukoshi; Yukio Yanagisawa
    The 8th International Symposium on Advanced Environmental Monitoring  2010
  • Association between Volatile Organic Compounds and Particulate Matters in Microenvironments  [Not invited]
    Intan Nadrah Zulkamar; Atsushi Mizukoshi; Miyuki Noguchi; Yukio Yanagisawa
    ISES-ISEE 2010  2010
  • 飯塚淳; 水越厚史; 齋藤京子; 八巻高子; 野口美由貴; 柳沢幸雄
    平成21年度室内環境学会学術大会  2009/12
  • 石塚祐輔; 野口美由貴; 水越厚史; 柳沢幸雄
    平成21年度室内環境学会学術大会  2009/12
  • 野口美由貴; 八巻高子; 水越厚史; 柳沢幸雄
    平成21年度室内環境学会学術大会  2009/12
  • 水越厚史; 野口美由貴; 柳田秀隆; 柳沢幸雄
    平成21年度室内環境学会学術大会  2009/12
  • 山下喬子; 野口美由貴; 水越厚史; 柳沢幸雄
    第46回環境工学研究フォーラム  2009/11
  • SHIRATO Shintaro; NOGUCHI Miyuki; MIZUKOSHI Atsushi; IIZUKA Atsushi; YAMASAKI Akihiro; YANAGISAWA Yukio
    創立50周年第50回大気環境学会年会  2009/09
  • MIZUKOSHI Atsushi; NOGUCHI Miyuki; IIZUKA Atsushi; INOUE Yasuo; YANAGISAWA Yukio
    創立50周年第50回大気環境学会年会  2009/08
  • Decreasing method of VOCs emission from building materials using ozonolysis  [Not invited]
    Miyuki Noguchi; Atsushi Mizukoshi; Yukio Yanagisawa
    Healthy Buildings  2009
  • 篠原直秀; 大西允人; 水越厚史; 柳沢幸雄
    平成20年度室内環境学会総会  2008/12
  • 山川陽; 熊谷一清; 野口美由貴; 水越厚史; 柳沢幸雄
    平成20年度室内環境学会総会  2008/12
  • OKA Kentaro; MIZUKOSHI Atsushi; INOUE Yasuo; NOGUCHI Miyuki; KUMAGAI Kazukiyo; YANAGISAWA Yukio
    第49回大気環境学会年会  2008/09
  • NOGUCHI Miyuki; MIZUKOSHI Atsushi; YAMASHITA Kyoko; KUMAGAI Kazukiyo; YANAGISAWA Yukio
    第49回大気環境学会年会  2008/09
  • MIZUKOSHI Atsushi; NOGUCHI Miyuki; YANAGIDA Hidetaka; YAMASHITA Kyoko; YANAGISAWA Yukio
    第49回大気環境学会年会  2008/09
  • YAMASHITA Kyoko; MIZUKOSHI Atsushi; NOGUCHI Miyuki; KUMAGAI Kazukiyo; YANAGISAWA Yukio
    第49回大気環境学会年会  2008/09
  • 水越厚史; 熊谷一清; 山本尚理; 野口美由貴; 吉内一浩; 熊野宏昭; 小沢学; 松井孝子; 坂部貢; 柳沢幸雄
    第17回日本臨床環境医学会学術集会  2008/07
  • 黒崎陽介; 熊谷一清; 野口美由貴; 山本尚理; 水越厚史; 柳沢幸雄
    第17回日本臨床環境医学会学術集会  2008/07
  • A simple investigation method for screening of indoor air quality  [Not invited]
    Miyuki Noguchi; Atsushi Mizukoshi; Yosuke Kurosaki; Kazukiyo Kumagai; Yukio Yanagisawa
    Indoor Air  2008
  • 黒崎陽介; 熊谷一清; 野口美由貴; 山本尚理; 水越厚史; 柳沢幸雄
    平成19年度室内環境学会総会  2007/12
  • 水越厚史; 野口美由貴; 黒崎陽介; 柳沢幸雄
    第48回大気環境学会年会  2007/09
  • Kyoko Yamashita; Kazukiyo Kumagai; Myuki Noguchi; Naomichi Yamamoto; Yueyong Ni; Atsushi Mizukoshi; Yukio Yanagisawa
    The 6th International Conference on Indoor Air Quality Ventilation & Energy Conservation in Buildings  2007
  • Real-time measurements of VOC exposure and heart rate variability in indoor and outdoor environments  [Not invited]
    Atsushi Mizukoshi; Naomichi Yamamoto; Kumagai Kumagai; Kazuhiro Yoshiuchi; Hiroaki Kumano; Yukio Yanagisawa
    The 6th International Conference on Indoor Air Quality Ventilation & Energy Conservation in Buildings  2007
  • 倪悦勇; 水越厚史; 熊谷一清; 野口美由貴; 柳沢幸雄
    2006年度室内環境学会総会  2006/12
  • 水越厚史; 野口美由貴; 熊谷一清; 柳沢幸雄
    第15回日本臨床環境医学会学術集会  2006
  • TAKAUE KOSUKE; KUMAGAI KAZUKIYO; MIZUKOSHI ATSUSHI; NOGUCHI MIYUKI; YANAGISAWA YUKIO
    第23回空気清浄とコンタミネーションコントロール研究大会  2006
  • 水越厚史; 熊谷一清; 柳沢幸雄
    2005年度室内環境学会総会  2005/12
  • The commuters' exposure to volatile organic compounds in the transportation in Tokyo, Japan  [Not invited]
    Atsushi Mizukoshi; Naohide Shinohara; Yukio Yanagisawa
    15th Ann. Conf. of the Int. Society of Exposure Analysis  2005
  • 水越厚史; 熊谷一清; 松井孝子; 坂部貢; 宮田幹夫; 石川哲; 土本寛二; 柳沢幸雄
    第14回日本臨床環境医学会総会  2005
  • Exposure Assessment to VOCs by Breath Analysis  [Not invited]
    Atsushi Mizukoshi; Kazukiyo Kumagai; Naohide Shinohara; Minoru Fujii; Yukio Yanagisawa
    14th Ann. Conf. of the Int. Society of Exposure Analysis  2004
  • 水越厚史; 熊谷一清; 篠原直秀; 藤井実; 柳沢幸雄
    第13回日本臨床環境医学会総会  2004
  • 篠原直秀; 甲斐雄也; 常名美貴; 水越厚史; 奥泉裕美子; 熊谷一清; 柳沢幸雄
    平成15年度室内環境学会総会  2003/12
  • 水越厚史; 熊谷一清; 篠原直秀; 奥泉裕美子; 藤井実; 柳沢幸雄
    平成15年度室内環境学会総会  2003/12
  • 水越厚史; 熊谷一清; 篠原直秀; 藤井実; 柳沢幸雄
    平成15年度室内環境学会総会  2003/12
  • Passive parallel VOCs and ventilation rate sampler  [Not invited]
    Yumiko Okuizumi; Kazukiyo Kumagai; Minoru Fujii; Hiroshi Yoshino; Naohide Shinohara; Atsushi Mizukoshi; Yukio Yanagisawa
    Healthy Buildings 2003  2003
  • 水越厚史; 熊谷一清; 篠原直秀; 藤井実; 柳沢幸雄
    第13回日本臨床環境医学会総会  2003

MISC

Industrial Property Rights

Awards & Honors

  • 2023/07 近畿大学医学部 2022年度 Good Support Teacher 賞
     
    受賞者: 水越 厚史
  • 2022/12 室内環境学会 2022年度 室内環境学会査読者賞
     
    受賞者: 水越厚史
  • 2021/07 近畿大学医学会 2021年度近畿大学医学会賞
     
    受賞者: 水越厚史
  • 2020/07 近畿大学医学会 2020年度近畿大学医学会賞
     
    受賞者: 水越厚史
  • 2016/06 近畿大学医学会 平成28年近畿大学医学会賞
     
    受賞者: 水越 厚史
  • 2015/12 室内環境学会 平成27年度室内環境学会賞・論文賞
     省エネルギーとシックビル対策を配慮した室内CO2及びTVOC濃度を指標とする空調制御の検討 
    受賞者: 水越厚史;野口美由貴;山本総一朗;川上梨沙;大塚俊裕;山口一;柳沢幸雄
  • 2012/12 室内環境学会 室内環境学会論文賞
     フォトフェントン反応を用いた気液接触型の新規空気清浄法の開発 
    受賞者: 徳村雅弘;和田友布子;宇佐美友理;水越厚史;野口美由貴;柳沢幸雄
  • 2011/12 室内環境学会 平成22年度室内環境学会学術大会大会長奨励賞
     室内環境における有機化合物のオゾン酸化反応による粒子生成 
    受賞者: 石塚祐輔;野口美由貴;水越厚史;酒井裕香;山崎章弘;柳沢幸雄
  • 2011 分離技術会 分離技術会奨励賞
     反応吸収を用いた空気清浄法の開発 
    受賞者: 宇佐美友理;和田友布子;徳村雅弘;水越厚史;野口美由貴;柳沢幸雄
  • 2008/12 室内環境学会 平成19年度室内環境学会総会大会長奨励賞
     スギ材を介したアセトアルデヒドの生成－酵素反応の検証実験－ 
    受賞者: 黒崎陽介;熊谷一清;野口美由貴;山本尚理;水越厚史;柳沢幸雄

Research Grants & Projects

  • Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)
    Date (from‐to) : 2020/04 -2023/03 
    Author : 水越 厚史; 奥村 二郎; 東 賢一; 中間 千香子; 北條 祥子
     
    環境過敏症は、通常、問題にならない僅かなレベルの化学物質への曝露や物理的影響などの環境因子により、全身の様々な症状が生じる病態である。近年、生活環境は急速に変化し、コロナ禍も相まって、環境過敏症の発症や病態に関係する環境因子は多様化している。そこで本研究では、環境過敏症に関係する環境因子を把握するための質問票を開発し、質問票を用いた実態調査を行うことで、環境過敏症の症状を訴える人の割合や発症・症状発現に関係する環境因子、日常生活における環境バリアを明らかにすることを目的としている。 本年度は引き続き文献調査を基に質問票を精査し、環境過敏症の発症と病態の機序を明らかにすることに主眼を置いて、発症の原因（きっかけ）と症状を誘発する環境因子について明確に区別して回答が得られるように改変した。また、環境過敏症の発症予防に関する最新の研究の情報を集約するため、日本臨床環境医学会および室内環境学会の環境過敏症分科会と生活環境と健康研究会の主催で合同研究会を2回オンラインにて開催し、研究会での情報、議論を質問票に反映させた。上記の作業から派生して、環境過敏症に関する国際共通の質問票やそれらを用いた調査研究、環境過敏症の定義や仮説についてまとめた総説が日本自律神経学会の学会誌「自律神経」に掲載された。また、次年度発刊の室内環境学会誌「室内環境」に特集「マルチ異分野の研究者からみた室内環境と環境過敏症：科学的究明と発症予防を目指して」の企画をした。
  • Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B)
    Date (from‐to) : 2019/04 -2022/03 
    Author : 篠原 直秀; 鍵 直樹; 関根 嘉香; 水越 厚史; 東 賢一; 金 勲
  • Kindai University：2021 All-Kindai University support project against COVID-19
    Date (from‐to) : 2021/07 -2022 
    Author : Kenichi Azuma; Atsushi Mizukoshi; Jiro Okumura
  • Kindai University：ALL-KINDAI UNIVERSITY SUPPORT PROJECT AGAINST COVID-19
    Date (from‐to) : 2020/07 -2021/06 
    Author : 東 賢一; 水越厚史; 中間千香子; 奥村二郎; 林 基哉; 金 勲; 鍵 直樹; 柳 宇
  • Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B)
    Date (from‐to) : 2016/04 -2019/03 
    Author : Shinohara Naohide
     
    Emission and transfer of diethylhexyl phthalate (DEHP) from PVC sheet to air and house dust were determined for 1, 3, 7, and 14 days using passive flux sampler (PFS). The diffusion distances were set as 0.9, 1.85, 2.75, 3.8, 5.75 mm. As the house dust, 0.3, 1, 3, and 12 mg/cm2 of JIS standard dust 15, polyethylene particle, and soda lime glass particle were used. DEHP transfer to dust increase until 14 days. The transfer rate to dust from PVC sheet were not different among the different diffusion distanses.The transfer rates to dust were several tens times to several hundreds times higher than the emission rates to indoor air.
  • Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (B)
    Date (from‐to) : 2016/04 -2019/03 
    Author : MIZUKOSHI Atsushi; AZUMA kenichi; OKUMURA jiro; TOKUMURA masahiro; NAGANO akira; NOGUCHI miyuki; HOJO sachiko; YANAGISAWA yukio; YAMASAKI akihiro
     
    To clarify the atmospheric behavior of chemical compounds exhausted in material recycling of waste plastics, the effects of atmospheric chemical reactions on chemical compounds generated during plastic melting were investigated by simulation experiments, and the concentration change of an atmospheric chemical reaction product was observed in field surveys. In addition, to evaluate the health effects of exposure to environmental chemical compounds such as exhausted compounds, the standard values of the QEESI questionnaire were reset according to the current situation in Japan. Furthermore, we demonstrated the possibility of removing a volatile organic compound in air by the advanced oxidation process as a treatment method for exhausted chemical compounds.
  • Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (B)
    Date (from‐to) : 2013/04 -2016/03 
    Author : KONUMA Rumi; YOSHIDA Makoto; MIZUKOSHI Atsushi; KAWARADA Kensuke; IIDA Takahiko
     
    Wood decay leads to a significant increase of the risk of collapse in wood structures such as wood houses and exterior wood constructions, and a reduction in commercial value of the material itself by discoloration and staining. Microbial volatile organic compounds (MVOCs) could be used to nondestructively detect hidden wood decay fungi in dwellings. In this study, MVOCs emitted from wood decay fungi were analyzed by three methods (GC/MS with a thermal desorption system, PTR/MS, and HS/SPME/GC/MS), and it was clarified that the characteristics of each analytical methods. The relationships between the stages of wood-decay and MVOCs produced by wood rotting fungi were also obtained. MVOCs can be used as a tracer for the presence of wood-decay fungi for early detection of wood decay.
  • 消費者製品に含有されるSVOCの経皮経路の暴露評価に関する調査
    経済産業省：平成26年度 「化学物質管理分野における科学的知見の充実に向けた調査」
    Date (from‐to) : 2014/07 -2015/03 
    Author : 東 賢一
     
    SVOCの経皮経路の暴露評価を目標とし、必要な情報のうち、特に、皮膚移行、皮膚吸収に関わる暴露係数に注目してデータの収集・整理した。現存する暴露評価モデルやツールに基づき、必要となる暴露係数をリストアップして、文献調査により報告値をまとめた。事例研究としてこれらの値を用いて暴露シナリオを想定し、リスク評価を行った。また、より正確なSVOCの経皮経路の暴露評価を行うための今後の課題についてまとめた。
  • 室内空気中の準揮発性有機化合物の定量的評価と個人暴露量推定に関する調査
    経済産業省：化学物質のリスク評価手法の開発・改良に資する科学的知見の充実に向けた調査
    Date (from‐to) : 2013 -2014 
    Author : 野口美由貴
  • Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B)
    Date (from‐to) : 2009 -2011 
    Author : YANAGISAWA Yukio; MIZUKOSHI Atsushi; OCHIAI Seiji
     
    Organophosphorous compounds, which are used as insecticide and flame retardant, have delayed neurological toxicity and are suggested to be a cause of Chemical Sensitivity. In this study, the apparatus which can measure the emission amount of organophosphorous compounds in a real environment was developed. Emission amount can be known visually by enzyme inhibition reaction and color reaction. Detection by absorbance measurement is possible by 6-hour sampling, and visual judgment is possible by 24-hour sampling.
  • 化学物質過敏症患者の症状と化学物質濃度
    昭和シェル石油環境研究助成財団：
    Date (from‐to) : 2005 -2006 
    Author : 水越厚史

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