KURAOKA KoujiDepartment of Medicine Lecturer | |||
Last Updated :2024/04/25
Researcher Information
J-Global ID
Education
- 2003/04 - 2006/03 Kyoto University 大学院（博士課程後期 理学研究科
- 2001/04 - 2003/03 Kyoto University 大学院（博士課程前期 理学研究科
- 1997/04 - 2001/03 Kyoto University Faculty of Science
Association Memberships
Published Papers
- K. Kuraoka; N. Konoike; K. NakamuraNEUROSCIENCE PERGAMON-ELSEVIER SCIENCE LTD 304 71 - 80 0306-4522 2015/09 [Refereed]
The ability to categorize social information is essential to survive in a primate's social group. In the monkey brain, there are neural systems to categorize social information. Among these, the relationship between the amygdala and the ventrolateral prefrontal cortex (vlPFC) has recently gained focus with regard to emotion regulation. However, the processing of facial information and the functional differences in these two areas remain unclear. Thus, in this study, we examined the response properties of single neurons in the amygdala and vlPFC while presenting video clips of three types of facial emotions (aggressive threat, coo, and scream) in Macaca mulatta. Neurons in the amygdala were preferentially activated upon presentation of a scream facial expression, which is strongly negative, whereas the neurons in the vlPFC were activated upon presentation of coo, a facial expression with multiple meanings depending on the social context. Information analyses revealed that the amount of information conveyed by the amygdala neurons about the type of emotion transiently increased immediately after stimulus presentation. In contrast, the information conveyed by the vlPFC neurons showed sustained elevation during stimulus presentation. Therefore, our results suggest that the amygdala processes strong emotion roughly but rapidly, whereas the vlPFC spends a great deal of time processing ambiguous facial information in communication, and make an accurate decision from multiple possibilities based on memory. (C) 2015 IBRO. Published by Elsevier Ltd. All rights reserved. - Naho Konoike; Yuka Kotozaki; Shigehiro Miyachi; Carlos Makoto Miyauchi; Yukihito Yomogida; Yoritaka Akimoto; Koji Kuraoka; Motoaki Sugiura; Ryuta Kawashima; Katsuki NakamuraNeuroImage 63 (1) 328 - 38 2012/10Rhythm is an essential element of human culture, particularly in language and music. To acquire language or music, we have to perceive the sensory inputs, organize them into structured sequences as rhythms, actively hold the rhythm information in mind, and use the information when we reproduce or mimic the same rhythm. Previous brain imaging studies have elucidated brain regions related to the perception and production of rhythms. However, the neural substrates involved in the working memory of rhythm remain unclear. In addition, little is known about the processing of rhythm information from non-auditory inputs (visual or tactile). Therefore, we measured brain activity by functional magnetic resonance imaging while healthy subjects memorized and reproduced auditory and visual rhythmic information. The inferior parietal lobule, inferior frontal gyrus, supplementary motor area, and cerebellum exhibited significant activations during both encoding and retrieving rhythm information. In addition, most of these areas exhibited significant activation also during the maintenance of rhythm information. All of these regions functioned in the processing of auditory and visual rhythms. The bilateral inferior parietal lobule, inferior frontal gyrus, supplementary motor area, and cerebellum are thought to be essential for motor control. When we listen to a certain rhythm, we are often stimulated to move our body, which suggests the existence of a strong interaction between rhythm processing and the motor system. Here, we propose that rhythm information may be represented and retained as information about bodily movements in the supra-modal motor brain system.
- Koji Kuraoka; Katsuki NakamuraEUROPEAN JOURNAL OF NEUROSCIENCE WILEY-BLACKWELL 35 (9) 1504 - 1512 0953-816X 2012/05The primate amygdala consists of several subnuclei. Neurons in this brain area have been known to respond to stimuli belonging to specific categories of objects, such as faces, animals, and artifacts. However, little is known about the functional differences among the nuclei of the primate amygdala. To clarify functional differences among these subnuclei in object categorization, we compared the responsiveness of neuronal populations among the lateral, basal and central nuclei of the monkey amygdala. The activity of 203 neurons was recorded while video clips of 13 stimuli belonging to three categories (monkey, human, and artifact) were presented. Of these neurons, 37, 39 and 37 neurons in the lateral, basal and central nuclei, respectively, responded to at least one of the stimuli. We applied a cluster analysis to the neuronal population responses from these nuclei, and also calculated information about the three categories and monkey identity from each neuronal population. We found that the three categories and monkey identity could be more properly classified by neuronal responsiveness in the central nucleus, which is an output gate of the amygdala, than by that in the lateral and basal nuclei. These results suggest that the information about objects suitable for the generation of appropriate emotional response is built up within the primate amygdala via an intra-amygdala network from the lateral nucleus to the central nucleus.
- Koji Kuraoka; Katsuki NakamuraPHYSIOLOGY & BEHAVIOR PERGAMON-ELSEVIER SCIENCE LTD 102 (3-4) 347 - 355 0031-9384 2011/03Using an infrared thermographic system, we have demonstrated, as previously reported, that temperatures in the nasal region of macaque monkeys decrease during negative emotional states, such as when facing a threatening person. In this study, we explored the usefulness of measuring nasal skin temperatures in studies of monkey emotions as manifested by conspecific emotional behaviors and expressions. We measured nasal skin temperatures of rhesus monkeys (Macaca mulatto) in response to video clips, all showing monkeys: a raging individual (Experiment 1), three distinct emotional expressions (Experiment 2), and only faces or voices representing a threat (Experiment 3). We found that nasal skin temperatures significantly decreased in response to a threatening stimulus, even when the stimulus was a 20 image with digitized sound, similar to those used in many psychological or neurophysiological studies on animal emotion. Moreover, species-specific aggressive threats invariably elicited a decrease in nasal skin temperatures and skin conductance responses; however, screams or coos did not elicit this response. Simultaneous perception of both facial expressions and vocalizations induced a more prominent decrease in nasal skin temperatures than did the perception of facial expressions or vocalizations alone. Taken together, these data suggest that decreased nasal skin temperatures should be added to the list of indicators of emotional states in animals. (C) 2010 Elsevier Inc. All rights reserved.
- Koji Kuraoka; Katsuki NakamuraJOURNAL OF NEUROPHYSIOLOGY AMER PHYSIOLOGICAL SOC 97 (2) 1379 - 1387 0022-3077 2007/02The face and voice can independently convey the same information about emotion. When we see an angry face or hear an angry voice, we can perceive a person's anger. These two different sensory cues are interchangeable in this sense. However, it is still unclear whether the same group of neurons process signals for facial and vocal emotions. We recorded neuronal activity in the amygdala of monkeys while watching nine video clips of species-specific emotional expressions: three monkeys showing three emotional expressions (aggressive threat, scream, and coo). Of the 227 amygdala neurons tested, 116 neurons (51%) responded to at least one of the emotional expressions. These "monkey-responsive" neurons - that is, neurons that responded to monkey-specific emotional expression - preferred the scream to other emotional expressions irrespective of identity. To determine the element crucial to neuronal responses, the activity of 79 monkey-responsive neurons was recorded while a facial or vocal element of a stimulus was presented alone. Although most neurons (61/79, 77%) strongly responded to the visual but not to the auditory element, about one fifth (16/79, 20%) maintained a good response when either the facial or vocal element was presented. Moreover, these neurons maintained their stimulus-preference profiles under facial and vocal conditions. These neurons were found in the central nucleus of the amygdala, the nucleus that receives inputs from other amygdala nuclei and in turn sends outputs to other emotion-related brain areas. These supramodal responses to emotion would be of use in generating appropriate responses to information regarding either facial or vocal emotion.
- K Kuraoka; K NakamuraNEUROREPORT LIPPINCOTT WILLIAMS & WILKINS 17 (1) 9 - 12 0959-4965 2006/01The amygdala has been implicated in the processing of emotional expressions. Who makes the emotion and the type of emotion are important in producing appropriate responses. How amygdala neurons are affected by facial identity and type of emotion, however, has not yet been systematically examined. We examined the activity of amygdala neurons using nine monkey stimuli: 3 monkeys x 3 types of emotion. Of the 227 neurons tested, 77 responded to the monkey stimuli. The effects of facial identity and type of emotion on the response magnitude were significant in 48 and 57 neurons, respectively. Both effects were significant in 38 neurons. These results indicate that both facial identity and type of emotion have strong impacts on amygdala functions.
- K Nakayama; S Goto; K Kuraoka; K NakamuraPHYSIOLOGY & BEHAVIOR PERGAMON-ELSEVIER SCIENCE LTD 84 (5) 783 - 790 0031-9384 2005/04We established an infrared thermographic system for the detection of emotion-related temperature changes in rhesus monkeys (Macaca mulatta). We continuously measured temperatures of various facial regions of four rhesus monkeys during the presentation of a potentially 'threatening' person, i.e., a person in a laboratory coat with a catching net, who entered the experimental room and approached the monkeys. The temperatures were also measured before and after the presentation of the 'stimulation period.' The temperature of the nasal region decreased significantly within 10-30 s, and continued to decrease throughout the stimulation period. During this period, the monkeys frequently expressed silent bared-teeth face, staring open-mouth face, and lip-smacking, all of which were expressions of a negative emotion. Assuming that the monkeys experience the negative emotion when viewing the potentially threatening stimulus, we conclude that the decrease in nasal skin temperature is relevant to the alteration of the emotional state. The present findings suggest that nasal temperature can be a reliable and accurate indicator of a change from neutral to negative in emotional state of non-human primates. (c) 2005 Elsevier Inc. All rights reserved.
- Akihiro Izumi; Koji Kuraoka; Shozo Kojima; Katsuki NakamuraCOGNITIVE AFFECTIVE & BEHAVIORAL NEUROSCIENCE SPRINGER 1 (3) 266 - 269 1530-7026 2001/09We trained 2 monkeys to display facial actions in response to corresponding arbitrary visual cues. Each monkey executed the task successfully, and each displayed two different facial actions corresponding to either hand-sign or color cues. More than 90% of the responses were correct for each monkey. These results provide evidence that monkeys can execute facialactions in response to conditioned visual cues in the absence of social context. These data suggest that facial actions of monkeys are flexible enough for use in further laboratory investigations-for example, in studies on the neural mechanisms underlying the execution of actions.
Books etc
- 「カールソン神経科学テキスト」泰羅雅登; 中村克樹; 泉明宏; 臼井信男; 永福智志; 大石高生; 大木紫; 功刀浩; 倉岡康治; 齋藤慈子; 佐伯恵里奈; 筒井健一郎; 中村徳子; 野瀬出; 花沢明俊; 村田哲; 山下晶子 (Joint translation4章)丸善出版 2013/05 103-136
- 「日本のサル学のあした」中川尚史; 伊藤 毅; 森本直記; 山田一憲; 井上英治; 寺川眞理; 松田一希; 郷 もえ; 佐藤宏樹; 山田 彩; 澤田晶子; 風張喜子; 岩田有史; 坂牧はるか; 服部裕子; 小倉匡俊; 酒井朋子; 齋藤慈子; 山本真也; 倉岡康治; 林 美里; 友永雅己; 足立幾磨; 早川卓志; 松下裕香; 東島沙弥佳; 西岡佑一郎; 西川真理; 川添達朗; 松本卓也; 張 鵬; 山梨裕美; 山極寿一; 不破紅樹; 瀧本彩加; 齋藤亜矢; 兼子峰明; 郷 康広; 高井正成; 浅葉慎介; 藤田志歩; 杉浦秀樹; 中村美知夫; 松平一成; 松井 淳; 鈴木南美; 小薮大輔; 日暮泰男 (Joint work)京都通信社 2012/12 196-201
Conference Activities & Talks
- サル扁桃体の社会的情報と報酬情報の処理において、興奮性応答は抑制性応答よりも優位である倉岡康治; 中村加枝第43回日本神経科学大会 2020/07
- Segregated and overlapped processing of social and reward information in primate amygdalaK. KURAOKA; K. NAKAMURASociety for Neuroscience 2019/10
- Representation of social and emotional information in primate amygdala [Not invited]Koji Kuraoka; Kae Nakamura第42回日本神経科学大会 2019/07
- Neuronal activity related to preference of visual stimuli monkey amygdaia. [Not invited]K Kuraoka; M InaseSociety for Neuroscience meeting 2017 2017/11 Washington D.C，USA Society for Neuroscience
- 好ましい視覚情報に応答するサル扁桃体ニューロン [Not invited]倉岡 康治; 稲瀬 正彦第40回日本神経科学大会 2017/07 千葉
MISC
- Neural substrates for maintenance of rhythm informationKonoike N; Kotozaki Y; Miyachi S; Miyauchi CM; Yomogida Y; Akimoto Y; Kuraoka K; Sugiura M; Kawashima R; Nakamura K The 35th Annual Meeting of the Japan Neuroscience Society (2012/09-18-21, Nagoya) 2012 [Refereed]
- Koji Kuraoka; Katsuki Nakamura NEUROSCIENCE RESEARCH 71- E283 -E283 2011
- Different contributions of frontal, parietal, and temporal cortices to working memory of rhythm.Konoike N; Kotozaki Y; Miyachi S; Miyachi CM; Yomogida Y; Akimoto Y; Kuraoka K; Sugiura M; Kawashima R; Nakamura K 41th Annual meeting, Society for Neuroscience (2011/11, Washington, DC). 2011 [Refereed]
- Categorical representation of social information in the central nucleus of monkey amygdale.Kuraoka K; Nakamura K 41th Annual meeting, Society for Neuroscience (2011/11, Washington, DC). 2011 [Refereed]
- サルの扁桃体と腹外側前頭前皮質で異なる表情情報表現の時間的変化.倉岡康治; 中村克樹 第34回日本神経科学大会 (2011/09/14-17, 横浜) 2011 [Refereed]
- A subject with complete agenesis of the corpus callosumshowing interhemispheric functional connectivity.内田信也; 中原 潔; 緑川晶; 倉岡康治; 齋藤慈子; 河村満; 中村克樹 脳梁完全欠損者における半球間機能的結合性. Neuro2010 (2010年09月02日, 神戸市)． 2010/09 [Refereed]
- Interhemispheric functional connectivity in a subject with complete agenesis of the corpus callosum.Uchida S; Nakahara K; Midorikawa A; Kuraoka K; Saito A; Takemoto A; Kawamura M; Nakamura K 16th Annual Meeting of the Organization for Human Brain Mapping(HBM) (2010/06/06-10, Barcelona, Spain). 2010 [Refereed]
- Neural substrates to enhance social relationships.Kuraoka K; Uchida S; Nakamura K 16th Annual Meeting of the Organization for Human Brain Mapping (HBM) (2010/06/06-10, Barcelona, Spain). 2010 [Refereed]
- Vocalization as a specific trigger of emotional responsesKuraoka K; Nakamura K In SM. Brudzynski (Ed.), HANDBOOK OF MAMMALIAN VOCALIZATION 167 -175 2009 [Refereed][Invited]
- Koji Kuraoka; Katsuki Nakamura NEUROSCIENCE RESEARCH 58- S229 -S229 2007
- Katsuki Nakamura; Koji Kuraoka NEUROSCIENCE RESEARCH 58- S14 -S14 2007
- The primate amygdala integrates the face and voice emotion.Kuraoka, K; Nakamura, K Society for Neuroscience 35th Annual meeting (Nov. 2005, Washington, DC, USA). 2005 [Refereed]
- アカゲザルにおける情動刺激に対する自律神経応答倉岡康治; 中村克樹 第19回日本霊長類学会大会 (2003年6月, 仙台). 予稿集 : 47. 2003 [Refereed]
- K Nakayama; S Goto; K Kuraoka; M Tomonaga; K Nakamura ANTHROPOLOGICAL SCIENCE 110- (1) 132 -132 2002/01
- KURAOKA KOJI; IZUMI AKIHIRO; NAKAMURA KATSUKI 日本神経科学大会プログラム・抄録集 24th- 355 2001/09
- KURAOKA KOJI; IZUMI AKIHIRO; NAKAMURA KATSUKI 神経化学 40- (2/3) 411 2001/09