UEMATSU Yugo

    Department of Pharmacy Research associate
Last Updated :2024/05/19

Researcher Information

URL

ORCID ID

J-Global ID

Research Interests

  • 医療薬学   環境衛生学   公衆衛生学   

Research Areas

  • Life sciences / Clinical pharmacy
  • Life sciences / Pharmaceuticals - health and biochemistry

Academic & Professional Experience

  • 2024/04 - Today  Kindai UniversityFaculty of Pharmacy Department of PharmacyAssistant Professor
  • 2023/04 - 2024/03  Kindai University HospitalDepartment of PharmacyPharmacist
  • 2020/04 - 2023/03  Kindai University HospitalDepartment of PharmacyResident of Pharmacist

Education

  • 2019/04 - 2023/03  Kindai University  Graduate School of Pharmacy
  • 2013/04 - 2019/03  Kindai University  Faculty of Pharmacy  Department of Pharmacy

Association Memberships

  • 大阪府病院薬剤師会   日本病院薬剤師会   医療薬学会   日本公衆衛生学会   日本薬学会   

Published Papers

  • Yugo Uematsu; Fumihiko Ogata; Riko Okamoto; Mineaki Kabayama; Naohito Kawasaki
    Heliyon Elsevier BV 10 (8) e29649 - e29649 2405-8440 2024/04 [Refereed]
  • Yuri Mizuno; Fumihiko Ogata; Yugo Uematsu; Naohito Kawasaki
    Chemical and Pharmaceutical Bulletin 72 (3) 286 - 293 0009-2363 2024 
    To explore drug interactions involving sodium zirconium cyclosilicate hydrate (SZC) and concomitant drugs like calcium antagonists (amlodipine and nifedipine) and β-blockers (carvedilol and bisoprolol), we investigate how these concomitant drugs influenced the administration of SZC in an artificial intestinal juice. Initially, we assessed the potassium ion adsorption capacity, ranking it as follows: calcium polystyrene sulfonate (CPS, 54.9mg/g)
  • Fumihiko Ogata; Noriaki Nagai; Yugo Uematsu; Yuhei Kobayashi; Nanako Kitamura; Chalermpong Saenjum; Naohito Kawasaki
    RSC Sustainability 2024 
    Fine Na-type zeolite grains (ZE) were prepared by dry milling treatment (D-ZE) or wet milling treatment (W-ZE). Then, the prepared samples were characterized. The effective parameters of adsorption capacities including the initial concentration, adsorption temperature, pH, and contact time for lead-ion adsorption were determined. The results revealed that the adsorption capacity of lead ions was in the order of ZE (32.7 mg g-1) < D-ZE (70.7 mg g-1) < W-ZE (166.9 mg g-1). The results of the adsorption processes exhibited increased adsorption temperature, an increased pH of up to 5.0, and increased contact time. Pseudo-second-order model kinetic was observed, and the lead adsorbent isotherm followed the Langmuir and Freundlich models. Finally, one of the adsorption mechanisms was elucidated by analyzing the binding energy of lead (Pb) and lead (Pb) distribution before and after adsorption. Thus, the results serve as useful information for the adsorption of lead ions from aqueous solutions using ZE samples.
  • Fumihiko Ogata; Yugo Uematsu; Noriaki Nagai; Ibuki Kobata; Ayako Tabuchi; Chalermpong Saenjum; Takehiro Nakamura; Naohito Kawasaki
    Heliyon Elsevier BV 9 (3) e14503 - e14503 2405-8440 2023/03 [Refereed]
  • Yuri Mizuno; Yugo Uematsu; Kyohei Nishida; Fumihiko Ogata; Naohito Kawasaki
    Chemical & pharmaceutical bulletin 71 (9) 751 - 755 2023 [Refereed]
     
    This study evaluated the interaction between sodium polystyrene sulfonate (SPS) and several commonly used concomitant drugs, such as carvedilol, bisoprolol, imidapril, atorvastatin and azilsartan. The residual rate of adsorption 6 h after starting the experiment followed the order carvedilol (0.36%) < bisoprolol (19.7%) < imidapril (81.2%) < atorvastatin (86.5%) < azilsartan (87.9%) in artificial intestinal juice (pH 6.8). In addition, the pKa of carvedilol and bisoprolol was 8.0 and 9.6 and that of atorvastatin, azilsartan, and imidapril was 4.5, 6.1, and 2.4, respectively. These results indicate that the form (ionic or uncharged) of each drug is important to its reaction with SPS. Moreover, we demonstrated the effect of potassium ions (concentration of 1000 or 2000 mg/L) on the adsorption of concomitant drugs onto SPS in artificial intestinal juice. Our results show that the residual rate of adsorption of carvedilol and bisoprolol increases with increasing concentration of potassium ions whereas adsorption of potassium ions onto SPS was unaffected by carvedilol and bisoprolol under our experimental conditions. Finally, the obtained results revealed that interactions between SPS and carvedilol or bisoprolol readily occur in artificial intestinal juice.
  • Yugo Uematsu; Fumihiko Ogata; Kyohei Nishida; Yuri Mizuno; Masashi Yanae; Manabu Takegami; Takehiro Nakamura; Naohito Kawasaki
    Chemical and Pharmaceutical Bulletin Pharmaceutical Society of Japan 70 (12) 876 - 884 0009-2363 2022/12 [Refereed]
  • Fumihiko Ogata; Yugo Uematsu; Noriaki Nagai; Misaki Nakamura; Ayako Tabuchi; Chalermpong Saenjum; Takehiro Nakamura; Naohito Kawasaki
    Bioresource Technology Reports Elsevier BV 20 101238 - 101238 2589-014X 2022/12 [Refereed]
  • Ayako Tabuchi; Fumihiko Ogata; Yugo Uematsu; Megumu Toda; Masashi Otani; Chalermpong Saenjum; Takehiro Nakamura; Naohito Kawasaki
    Molecules MDPI AG 27 (8) 2392 - 2392 2022/04 [Refereed]
     
    We combined a nickel–aluminum–zirconium complex hydroxide (NAZ) with colloidal silica as a binder to prepare a granulated agent for adsorbing heavy metals from aqueous media. Three samples with different particle diameters were prepared to evaluate the effects on the properties: small (NAZ-S), medium (NAZ-M), and large (NAZ-L). We confirmed the granulation of the prepared samples at a binder content of 25%. NAZ-S had the largest specific surface area and number of hydroxyl groups, followed by NAZ-M and then NAZ-L. Regarding the adsorption capacity, NAZ-S adsorbed the most chromium(VI) ions followed by NAZ-M and then NAZ-L. The binding energy of Cr(2p) at 575–577 eV was detected after adsorption, and the effects of the temperature, contact time, and pH on the adsorption of chromium(VI) ions were evaluated. We identified the following adsorption mechanism: ion exchange with sulfate ions in the interlayer region of the NAZ samples. Finally, the chromium(VI) ions adsorbed by the NAZ samples were easily desorbed using a desorption solution. The results showed that NAZ offers great potential for the removal of chromium(VI) ions from aqueous solutions.
  • Fumihiko Ogata; Yugo Uematsu; Ayako Tabuchi; Takehiro Nakamura; Naohito Kawasaki
    BPB Reports Pharmaceutical Society of Japan 5 (3) 42 - 44 2022 [Refereed]
  • Yugo Uematsu; Masashi Yanae; Manabu Takegami; Fumihiko Ogata; Takehiro Nakamura; Naohito Kawasaki
    BPB Reports Pharmaceutical Society of Japan 5 (3) 33 - 38 2022 [Refereed]
  • Yugo Uematsu; Fumihiko Ogata; Noriaki Nagai; Chalermpong Saenjum; Takehiro Nakamura; Naohito Kawasaki
    Heliyon Elsevier BV 7 (7) e07644 - e07644 2405-8440 2021/07 [Refereed]
  • Fumihiko Ogata; Yugo Uematsu; Yuhei Kobayashi; Yuuka Izutani; Chalermpong Saenjum; Megumu Toda; Masashi Otani; Takehiro Nakamura; Naohito Kawasaki
    Chemical and Pharmaceutical Bulletin Pharmaceutical Society of Japan 69 (1) 86 - 91 0009-2363 2021/01 [Refereed]
  • Fumihiko Ogata; Yugo Uematsu; Takehiro Nakamura; Naohito Kawasaki
    YAKUGAKU ZASSHI Pharmaceutical Society of Japan 140 (12) 1463 - 1470 0031-6903 2020/12 [Refereed]
  • Fumihiko Ogata; Yuhei Kobayashi; Yugo Uematsu; Titikan Mongkolsiri; Chalermpong Saenjum; Takehiro Nakamura; Naohito Kawasaki
    Bioresource Technology Reports Elsevier BV 12 100563 - 100563 2589-014X 2020/12 [Refereed]
  • Fumihiko Ogata; Yugo Uematsu; Mako Fukuda; Chalermpong Saenjum; Mineaki Kabayama; Takehiro Nakamura; Naohito Kawasaki
    Journal of Environmental Chemical Engineering Elsevier BV 8 (5) 104385 - 104385 2213-3437 2020/10 [Refereed]
  • Fumihiko Ogata; Yuhei Kobayashi; Yugo Uematsu; Takehiro Nakamura; Naohito Kawasaki
    YAKUGAKU ZASSHI Pharmaceutical Society of Japan 140 (5) 729 - 737 0031-6903 2020/05 [Refereed]
  • Yugo Uematsu; Fumihiko Ogata; Chalermpong Saenjum; Takehiro Nakamura; Naohito Kawasaki
    Sustainability MDPI AG 12 (7) 2895 - 2895 2020/04 [Refereed]
     
    To confirm the capability and mechanisms of Sr(II) and Cs(I) adsorption from the aqueous phase using basil seed (BS), virgin BS, calcined BS (BS500 and BS1000), and enzymatically treated BS, namely Mannanase BGM (M-BS), Pectinase G (P-BS), Hemicellulase (H-BS), and Cellulase A (C-BS) was evaluated. The adsorption capabilities of Sr(II) and Cs(I) of various BS adsorbents were also evaluated. The quantity of Sr(II) and Cs(I) adsorbed onto BS was greater than that of BS500 or BS1000, suggesting that the physicochemical characteristics of the BS surface affected Sr(II) and Cs(I) removal from the aqueous phase. Furthermore, the quantity of Sr(II) and Cs(I) adsorbed onto virgin BS was greater than that of enzymatically treated BS, indicating that glucomannan or (1,4)-xylan in the cellulosic hydrocolloid of the BS strongly affected the adsorption capability of Cs(I) or Sr(II) (except for M-BS in Sr(II) adsorption). Our obtained results indicate that, as an adsorbent, BS was capable of removing Sr(II) and Cs(I) from the aqueous solution.

Awards & Honors

  • 2023/03 公益社団法人 日本薬学会 学生優秀発表賞(ポスター賞)
     水酸化マグネシウムによる水環境中からのリン酸イオン回収機構の解明 
    受賞者: 植松 勇伍;福田 真子;緒方 文彦;中村 武浩;川﨑 直人
  • 2022/03 公益社団法人 日本薬学会 学生優秀発表賞(口頭発表)
     ポリスチレンスルホン酸ナトリウムを用いた併用薬の吸着に関する基礎的検討 
    受賞者: 植松 勇伍;緒方 文彦;栁江 正嗣;淺野 肇;吉年 正宏;竹上 学;中村 武浩;川﨑 直人
  • 2019/10 日本公衆衛生学会 優秀ポスター賞
     ココヤシファイバーによるメチレンブルー除去 
    受賞者: 植松 勇伍;緒方 文彦;中村 武浩;山城 海渡;川﨑 直人


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