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Youjirou Koutake


FacultyDepartment of Biological and Environmental Chemistry / Graduate School of Industory
Commentator Guide
Last Updated :2018/07/22

Research Activities

Research Areas

  • Oncology, Tumor biology

Research Interests

  • ARF, p16, p53, ANRIL

Published Papers

  • A novel resveratrol derivative selectively inhibits the proliferation of colorectal cancer cells with KRAS mutation., Okamoto H, Matsukawa T, Doi S, Tsunoda T, Sawata Y, Naemura M, Ohnuki K, Shirasawa S, Kotake Y., Mol Cell Biochem., 442, 39 - 45, May 2018 , Refereed
  • The Long Noncoding RNA OIP5-AS1 Is Involved in the Regulation of Cell Proliferation., yojiro KotakeNaemura M, Kuroki M, Tsunoda T, Arikawa N, Sawata Y, Shirasawa S, Kotake Y., Anticancer Res. , 38(1), 77 - 81, Jan. 2018 , Refereed
  • Homeobox Transcription Factor NKX2-1 Promotes Cyclin D1 Transcription in Lung Adenocarcinomas., Harada M, Sakai S, Ohhata T, Kitagawa K, Mikamo M, Nishimoto K, Uchida C, Niida H, Kotake Y, Sugimura H, Suda T, Kitagawa M., Mol Cancer Res. , 15(10), 1388 - 1397, Oct. 2017 , Refereed
  • Silencing of BCR/ABL Chimeric Gene in Human Chronic Myelogenous Leukemia Cell Line K562 by siRNA-Nuclear Export Signal Peptide Conjugates., Shinkai Y, Kashihara S, Minematsu G, Fujii H, Naemura M, Kotake Y, Morita Y, Ohnuki K, Fokina AA, Stetsenko DA, Filichev VV, Fujii M., Nucleic Acid Ther, 27(3), 168 - 175, Jun. 2017 , Refereed
  • Y-box Binding Protein 1 Is Involved in Regulating the G2/M Phase of the Cell Cycle., Anticancer Res, 37(4), 1603 - 1608, Apr. 2017 , Refereed
  • Long Noncoding RNA PANDA Positively Regulates Proliferation of Osteosarcoma Cells., Kotake Y, Goto T, Naemura M, Inoue Y, Okamoto H, Tahara K., Anticancer Res, 37(1), 81 - 85, Jan. 2017 , Refereed
  • YB-1 promotes transcription of cyclin D1 in human non-small-cell lung cancers., HARADA Masanori, KOTAKE Yojiro, KOTAKE Yojiro, OHHATA Tatsuya, KITAGAWA Kyoko, NIIDA Hiroyuki, MATSUURA Shun, FUNAI Kazuhito, SUGIMURA Haruhiko, SUDA Takafumi, KITAGAWA Masatoshi, Genes to Cells, 19(6), 504 - 516, Jun. 2014 , Refereed
  • Cell cycle regulation by long non-coding RNAs., KITAGAWA Masatoshi, KITAGAWA Kyoko, KOTAKE Yojiro, KOTAKE Yojiro, NIIDA Hiroyuki, OHHATA Tatsuya, Cell Mol Life Sci, 70(24), 4785 - 4794, Dec. 2013 , Refereed
  • YB1 binds to and represses the p16 tumor suppressor gene., KOTAKE Yojiro, OZAWA Yuichi, HARADA Masanori, KITAGAWA Kyoko, NIIDA Hiroyuki, MORITA Yasutaka, TANAKA Kenji, SUDA Takafumi, KITAGAWA Masatoshi, Genes Cells, 18(11), 999 - 1006, Nov. 2013 , Refereed
  • Long Non-coding RNAs Involved in Cancer Development and Cell Fate Determination., Kitagawa M., Ohhata T., Kotake Y., Curr Drug Targets., 13(13), 1616 - 1621, Dec. 2012 , Refereed
  • The amelioration of renal damage in Skp2-deficient mice canceled by p27 Kip1 deficiency in Skp2-/- p27-/- mice., Nakayama K.I., Nakayama K., Kitagawa M., Yamamoto T., Suzuki S., Misaki T., Fukasawa H., Ohashi N., Togawa A., Kotake Y., Kitagawa K., Niida H., Liu N., PLoS One, 7(4), Apr. 2012 , Refereed
  • Chk1 phosphorylates the tumour suppressor Mig-6, regulating the activation of EGF signalling., LIU Ning, LIU Ning, MATSUMOTO Masaki, KITAGAWA Kyoko, KOTAKE Yojiro, SUZUKI Sayuri, SHIRASAWA Senji, NAKAYAMA Keiichi I, NAKANISHI Makoto, NIIDA Hiroyuki, KITAGAWA Masatoshi, EMBO J, 31(10), 2365 - 2377, Apr. 2012 , Refereed
  • Up-regulation of Cks1 and Skp2 with TNFα/NF-κB Signaling in Chronic Progressive Nephropathy., SUZUKI Sayuri, FUKASAWA Hirotaka, MISAKI Taro, TOGAWA Akashi, OHASHI Naro, KITAGAWA Kyoko, KOTAKE Yojiro, NIIDA Hiroyuki, HISHIDA Akira, YAMAMOTO Tatsuo, KITAGAWA Masatoshi, Genes to Cells, 16(11), 1110 - 1120, Nov. 2011 , Refereed

Conference Activities & Talks

  • The regulation of RB/p53 pathway by long noncoding RNAs,   2013 12 12
  • Elucidation of the action mechanism of long non-coding RNA, ANRIL which regulates cell proliferation,   2013 12 12
  • Recent progress of long non-coding RNA research,   2012 09
  • Chk1 phosphorylates the tumor suppressor Mig-6, regulating the activation of EGF signaling,   2012 05