ANO YusukeDepartment of Biotechnology and Chemistry Lecturer |
The fluoride anion-initiated reaction of phenyl aromatic carboxylates with (trifluoromethyl)trimethylsilane (Me3SiCF3) that results in the formation of
The nickel-catalyzed reductive cleavage of esters in the absence of an external reductant, which involves the cleavage of an inert acyl C–O bond in O-alkyl esters is reported.
The reaction of ortho-methyl-substituted aromatic amides with maleimides in the presence of Pd(OAc)2 and AgOAc results in C–H alkylation only at the ortho-methyl C–H bond.
A computational methodology was used to collect detailed mechanistic information on the cobalt-catalyzed C–H iodination of aromatic amides with molecular iodine using an N,N′-bidentate directing group.
The reaction of N-heteroaromatic compounds, such as 2-aryl-pyrrole, benzimidazole, imidazole, indole, and pyrazole derivatives, with alkynes in the presence of a catalytic amount of a nickel complex results in C–H/N–H oxidative annulation.